EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000137200 (Gene tree)
Gene ID: 23070
Gene Symbol: CMTR1
Alias: MTr1|ISG95|KIAA0082|FTSJD2
Full Name: cap methyltransferase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 49,697 bases
Position: chr6:37,433,131-37,482,827
Accession: 21077
RBP type: canonical RBP
Summary: (Cap Methyltransferase 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and mRNA (nucleoside-2'-O-)-methyltransferase activity. An important paralog of this gene is CMTR2.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000362550	FtsJ	PF01728.19	1.4e-36	1	1
ENSP00000414233	FtsJ	PF01728.19	1.3e-24	1	1
ENSP00000414233	G-patch	PF01585.23	9e-13	1	1
ENSP00000362550	G-patch	PF01585.23	1.8e-12	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18533109	The human interferon-regulated ISG95 protein interacts with RNA polymerase II and shows methyltransferase activity.	Biochem Biophys Res Commun	2008 Aug 8	Haline-Vaz T	doi: 10.1016/j.bbrc.2008.05.137

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000373451	CMTR1-201	4033	XM_005248955	ENSP00000362550	835 (aa)	XP_005249012	Q8N1G2
ENST00000475364	CMTR1-205	1032	-	ENSP00000432114	113 (aa)	-	H0YCQ1
ENST00000457419	CMTR1-203	769	-	ENSP00000393893	156 (aa)	-	H0Y4T0
ENST00000471097	CMTR1-204	457	-	-	- (aa)	-	-
ENST00000493656	CMTR1-206	550	-	-	- (aa)	-	-
ENST00000455891	CMTR1-202	1280	-	ENSP00000414233	372 (aa)	-	Q5T7F5

Gene Model

Click here to download ENSG00000137200's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000137200	Myocardial Infarction	5.0323934E-004	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000137200	rs369566109	6	37468054	?	Cognitive empathy	28584286	[0.18-0.45] unit increase	0.3132	EFO_0009183

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000137200's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000137200	CMTR1	93	75.862	ENSAPOG00000006151	cmtr1	99	73.575	Acanthochromis_polyacanthus
ENSG00000137200	CMTR1	100	97.076	ENSAMEG00000015322	CMTR1	94	94.911	Ailuropoda_melanoleuca
ENSG00000137200	CMTR1	92	75.694	ENSACIG00000005878	cmtr1	83	73.684	Amphilophus_citrinellus
ENSG00000137200	CMTR1	80	73.037	ENSAOCG00000010042	cmtr1	93	68.296	Amphiprion_ocellaris
ENSG00000137200	CMTR1	93	76.552	ENSAPEG00000005034	cmtr1	99	70.012	Amphiprion_percula
ENSG00000137200	CMTR1	93	75.172	ENSATEG00000010704	cmtr1	96	73.775	Anabas_testudineus
ENSG00000137200	CMTR1	99	82.992	ENSAPLG00000014262	CMTR1	99	82.992	Anas_platyrhynchos
ENSG00000137200	CMTR1	99	81.032	ENSACAG00000014369	CMTR1	99	81.032	Anolis_carolinensis
ENSG00000137200	CMTR1	100	100.000	ENSANAG00000020879	CMTR1	100	98.802	Aotus_nancymaae
ENSG00000137200	CMTR1	93	77.241	ENSACLG00000015901	cmtr1	99	70.322	Astatotilapia_calliptera
ENSG00000137200	CMTR1	93	72.414	ENSAMXG00000012891	cmtr1	96	59.429	Astyanax_mexicanus
ENSG00000137200	CMTR1	100	95.210	ENSBTAG00000017091	CMTR1	100	95.210	Bos_taurus
ENSG00000137200	CMTR1	75	58.537	WBGene00013160	Y53F4B.13	85	42.533	Caenorhabditis_elegans
ENSG00000137200	CMTR1	100	100.000	ENSCJAG00000005567	CMTR1	100	98.922	Callithrix_jacchus
ENSG00000137200	CMTR1	100	96.886	ENSCAFG00000001477	CMTR1	100	96.886	Canis_familiaris
ENSG00000137200	CMTR1	100	96.886	ENSCAFG00020007413	CMTR1	100	96.886	Canis_lupus_dingo
ENSG00000137200	CMTR1	100	95.210	ENSCHIG00000024476	CMTR1	99	95.210	Capra_hircus
ENSG00000137200	CMTR1	100	94.132	ENSTSYG00000001508	CMTR1	100	94.132	Carlito_syrichta
ENSG00000137200	CMTR1	99	95.833	ENSCAPG00000009501	CMTR1	99	90.734	Cavia_aperea
ENSG00000137200	CMTR1	99	95.833	ENSCPOG00000010298	CMTR1	99	90.614	Cavia_porcellus
ENSG00000137200	CMTR1	100	93.533	ENSCCAG00000033509	CMTR1	100	99.187	Cebus_capucinus
ENSG00000137200	CMTR1	100	99.880	ENSCATG00000043987	CMTR1	100	99.880	Cercocebus_atys
ENSG00000137200	CMTR1	99	97.024	ENSCLAG00000012181	CMTR1	99	91.367	Chinchilla_lanigera
ENSG00000137200	CMTR1	100	99.880	ENSCSAG00000010493	CMTR1	100	99.880	Chlorocebus_sabaeus
ENSG00000137200	CMTR1	94	94.083	ENSCHOG00000004736	CMTR1	100	93.026	Choloepus_hoffmanni
ENSG00000137200	CMTR1	99	85.474	ENSCPBG00000025335	CMTR1	99	85.474	Chrysemys_picta_bellii
ENSG00000137200	CMTR1	89	51.200	ENSCING00000024328	-	99	49.685	Ciona_intestinalis
ENSG00000137200	CMTR1	100	99.880	ENSCANG00000019286	CMTR1	100	99.880	Colobus_angolensis_palliatus
ENSG00000137200	CMTR1	99	91.357	ENSCGRG00001022818	Cmtr1	99	91.357	Cricetulus_griseus_chok1gshd
ENSG00000137200	CMTR1	99	91.357	ENSCGRG00000014364	Cmtr1	99	91.357	Cricetulus_griseus_crigri
ENSG00000137200	CMTR1	99	68.383	ENSCSEG00000020697	cmtr1	99	68.383	Cynoglossus_semilaevis
ENSG00000137200	CMTR1	93	76.552	ENSCVAG00000021132	cmtr1	99	69.378	Cyprinodon_variegatus
ENSG00000137200	CMTR1	93	81.379	ENSDARG00000030830	cmtr1	99	70.913	Danio_rerio
ENSG00000137200	CMTR1	100	94.371	ENSDNOG00000048634	CMTR1	100	94.371	Dasypus_novemcinctus
ENSG00000137200	CMTR1	97	94.932	ENSDORG00000005445	Cmtr1	100	94.949	Dipodomys_ordii
ENSG00000137200	CMTR1	89	38.781	FBgn0029693	CG6379	96	38.262	Drosophila_melanogaster
ENSG00000137200	CMTR1	100	96.450	ENSETEG00000003670	CMTR1	100	83.713	Echinops_telfairi
ENSG00000137200	CMTR1	97	58.940	ENSEBUG00000007471	cmtr1	91	58.931	Eptatretus_burgeri
ENSG00000137200	CMTR1	100	97.006	ENSEASG00005021434	CMTR1	100	97.006	Equus_asinus_asinus
ENSG00000137200	CMTR1	100	96.766	ENSECAG00000014822	CMTR1	100	97.396	Equus_caballus
ENSG00000137200	CMTR1	93	93.103	ENSEEUG00000008073	CMTR1	90	95.122	Erinaceus_europaeus
ENSG00000137200	CMTR1	93	77.931	ENSELUG00000004404	cmtr1	99	73.924	Esox_lucius
ENSG00000137200	CMTR1	100	97.605	ENSFCAG00000006744	CMTR1	100	97.605	Felis_catus
ENSG00000137200	CMTR1	99	81.633	ENSFALG00000011244	CMTR1	99	81.633	Ficedula_albicollis
ENSG00000137200	CMTR1	99	95.833	ENSFDAG00000013513	CMTR1	99	92.197	Fukomys_damarensis
ENSG00000137200	CMTR1	93	76.552	ENSFHEG00000001086	cmtr1	99	72.096	Fundulus_heteroclitus
ENSG00000137200	CMTR1	93	77.241	ENSGMOG00000014482	cmtr1	99	66.468	Gadus_morhua
ENSG00000137200	CMTR1	99	84.154	ENSGALG00000010149	CMTR1	88	84.154	Gallus_gallus
ENSG00000137200	CMTR1	93	76.552	ENSGAFG00000010629	cmtr1	98	71.673	Gambusia_affinis
ENSG00000137200	CMTR1	93	75.862	ENSGACG00000011365	cmtr1	99	69.820	Gasterosteus_aculeatus
ENSG00000137200	CMTR1	99	85.354	ENSGAGG00000023136	CMTR1	99	85.354	Gopherus_agassizii
ENSG00000137200	CMTR1	100	100.000	ENSGGOG00000005640	CMTR1	100	100.000	Gorilla_gorilla
ENSG00000137200	CMTR1	93	77.241	ENSHBUG00000010146	cmtr1	99	70.322	Haplochromis_burtoni
ENSG00000137200	CMTR1	99	95.238	ENSHGLG00000019562	CMTR1	99	90.528	Heterocephalus_glaber_female
ENSG00000137200	CMTR1	99	95.238	ENSHGLG00100009312	CMTR1	99	91.837	Heterocephalus_glaber_male
ENSG00000137200	CMTR1	99	69.111	ENSHCOG00000011866	cmtr1	97	71.184	Hippocampus_comes
ENSG00000137200	CMTR1	99	71.703	ENSIPUG00000012160	cmtr1	99	71.823	Ictalurus_punctatus
ENSG00000137200	CMTR1	99	94.838	ENSSTOG00000016546	CMTR1	99	94.838	Ictidomys_tridecemlineatus
ENSG00000137200	CMTR1	100	91.497	ENSJJAG00000018982	Cmtr1	99	91.497	Jaculus_jaculus
ENSG00000137200	CMTR1	93	76.552	ENSKMAG00000011344	cmtr1	99	70.012	Kryptolebias_marmoratus
ENSG00000137200	CMTR1	93	76.552	ENSLBEG00000021019	cmtr1	97	71.120	Labrus_bergylta
ENSG00000137200	CMTR1	99	91.667	ENSLACG00000006958	CMTR1	99	77.612	Latimeria_chalumnae
ENSG00000137200	CMTR1	93	75.172	ENSLOCG00000017052	cmtr1	99	72.021	Lepisosteus_oculatus
ENSG00000137200	CMTR1	99	96.279	ENSLAFG00000017287	CMTR1	100	96.296	Loxodonta_africana
ENSG00000137200	CMTR1	100	99.880	ENSMFAG00000002390	CMTR1	100	99.880	Macaca_fascicularis
ENSG00000137200	CMTR1	100	100.000	ENSMMUG00000011573	CMTR1	100	100.000	Macaca_mulatta
ENSG00000137200	CMTR1	100	99.880	ENSMNEG00000039572	CMTR1	100	99.880	Macaca_nemestrina
ENSG00000137200	CMTR1	100	98.802	ENSMLEG00000037397	CMTR1	100	98.802	Mandrillus_leucophaeus
ENSG00000137200	CMTR1	93	75.172	ENSMAMG00000020706	cmtr1	99	69.065	Mastacembelus_armatus
ENSG00000137200	CMTR1	93	77.241	ENSMZEG00005017018	cmtr1	99	70.322	Maylandia_zebra
ENSG00000137200	CMTR1	99	84.034	ENSMGAG00000010739	CMTR1	99	84.034	Meleagris_gallopavo
ENSG00000137200	CMTR1	100	96.168	ENSMICG00000003366	CMTR1	99	96.168	Microcebus_murinus
ENSG00000137200	CMTR1	99	86.915	ENSMOCG00000014109	Cmtr1	99	86.915	Microtus_ochrogaster
ENSG00000137200	CMTR1	93	75.862	ENSMMOG00000015984	cmtr1	97	69.975	Mola_mola
ENSG00000137200	CMTR1	93	77.241	ENSMALG00000003836	cmtr1	99	68.383	Monopterus_albus
ENSG00000137200	CMTR1	99	90.276	MGP_CAROLIEiJ_G0021350	Cmtr1	99	90.276	Mus_caroli
ENSG00000137200	CMTR1	99	90.276	ENSMUSG00000024019	Cmtr1	100	92.121	Mus_musculus
ENSG00000137200	CMTR1	99	90.156	MGP_PahariEiJ_G0023669	Cmtr1	99	90.156	Mus_pahari
ENSG00000137200	CMTR1	99	90.156	MGP_SPRETEiJ_G0022264	Cmtr1	99	90.156	Mus_spretus
ENSG00000137200	CMTR1	100	97.605	ENSMPUG00000013910	CMTR1	100	97.605	Mustela_putorius_furo
ENSG00000137200	CMTR1	100	95.569	ENSMLUG00000006730	-	100	95.569	Myotis_lucifugus
ENSG00000137200	CMTR1	100	90.180	ENSMLUG00000024254	-	100	90.180	Myotis_lucifugus
ENSG00000137200	CMTR1	99	90.636	ENSNGAG00000010259	Cmtr1	99	90.636	Nannospalax_galili
ENSG00000137200	CMTR1	93	76.552	ENSNBRG00000017272	cmtr1	98	74.093	Neolamprologus_brichardi
ENSG00000137200	CMTR1	100	99.760	ENSNLEG00000011192	CMTR1	100	99.760	Nomascus_leucogenys
ENSG00000137200	CMTR1	93	82.759	ENSMEUG00000008971	CMTR1	85	86.621	Notamacropus_eugenii
ENSG00000137200	CMTR1	100	93.054	ENSOPRG00000012930	CMTR1	100	93.054	Ochotona_princeps
ENSG00000137200	CMTR1	99	90.396	ENSODEG00000017441	CMTR1	99	90.396	Octodon_degus
ENSG00000137200	CMTR1	93	76.552	ENSONIG00000013469	cmtr1	99	70.441	Oreochromis_niloticus
ENSG00000137200	CMTR1	95	80.726	ENSOANG00000013822	CMTR1	100	80.726	Ornithorhynchus_anatinus
ENSG00000137200	CMTR1	90	95.629	ENSOCUG00000008098	CMTR1	95	95.629	Oryctolagus_cuniculus
ENSG00000137200	CMTR1	97	76.159	ENSORLG00000013819	cmtr1	99	69.461	Oryzias_latipes
ENSG00000137200	CMTR1	97	76.316	ENSORLG00020012086	cmtr1	99	69.461	Oryzias_latipes_hni
ENSG00000137200	CMTR1	97	76.159	ENSORLG00015006909	cmtr1	99	69.461	Oryzias_latipes_hsok
ENSG00000137200	CMTR1	93	78.621	ENSOMEG00000008016	cmtr1	99	70.419	Oryzias_melastigma
ENSG00000137200	CMTR1	99	95.918	ENSOGAG00000000916	CMTR1	99	95.918	Otolemur_garnettii
ENSG00000137200	CMTR1	100	95.210	ENSOARG00000014698	CMTR1	99	95.210	Ovis_aries
ENSG00000137200	CMTR1	100	100.000	ENSPPAG00000035778	CMTR1	100	100.000	Pan_paniscus
ENSG00000137200	CMTR1	100	96.048	ENSPPRG00000022660	CMTR1	100	96.048	Panthera_pardus
ENSG00000137200	CMTR1	100	95.928	ENSPTIG00000020536	CMTR1	100	95.928	Panthera_tigris_altaica
ENSG00000137200	CMTR1	100	100.000	ENSPTRG00000018122	CMTR1	100	100.000	Pan_troglodytes
ENSG00000137200	CMTR1	100	99.760	ENSPANG00000021276	CMTR1	100	99.760	Papio_anubis
ENSG00000137200	CMTR1	93	75.172	ENSPKIG00000005638	cmtr1	99	70.144	Paramormyrops_kingsleyae
ENSG00000137200	CMTR1	99	86.074	ENSPSIG00000018204	CMTR1	99	86.074	Pelodiscus_sinensis
ENSG00000137200	CMTR1	92	75.524	ENSPMGG00000008947	cmtr1	100	69.299	Periophthalmus_magnuspinnatus
ENSG00000137200	CMTR1	99	91.597	ENSPEMG00000006218	Cmtr1	99	91.597	Peromyscus_maniculatus_bairdii
ENSG00000137200	CMTR1	90	66.356	ENSPMAG00000005418	cmtr1	95	66.095	Petromyzon_marinus
ENSG00000137200	CMTR1	99	85.594	ENSPCIG00000024459	CMTR1	99	85.594	Phascolarctos_cinereus
ENSG00000137200	CMTR1	93	75.862	ENSPFOG00000001587	cmtr1	99	70.131	Poecilia_formosa
ENSG00000137200	CMTR1	93	75.862	ENSPLAG00000015883	cmtr1	99	70.012	Poecilia_latipinna
ENSG00000137200	CMTR1	93	75.862	ENSPMEG00000014227	cmtr1	99	70.012	Poecilia_mexicana
ENSG00000137200	CMTR1	93	75.172	ENSPREG00000001500	cmtr1	99	69.773	Poecilia_reticulata
ENSG00000137200	CMTR1	100	100.000	ENSPPYG00000016562	CMTR1	100	100.000	Pongo_abelii
ENSG00000137200	CMTR1	93	93.103	ENSPCAG00000016015	CMTR1	100	83.493	Procavia_capensis
ENSG00000137200	CMTR1	99	94.484	ENSPCOG00000022141	CMTR1	98	94.484	Propithecus_coquereli
ENSG00000137200	CMTR1	100	94.850	ENSPVAG00000016511	CMTR1	100	94.850	Pteropus_vampyrus
ENSG00000137200	CMTR1	93	77.241	ENSPNYG00000009903	cmtr1	99	70.203	Pundamilia_nyererei
ENSG00000137200	CMTR1	93	75.136	ENSPNAG00000028223	cmtr1	91	72.572	Pygocentrus_nattereri
ENSG00000137200	CMTR1	99	90.156	ENSRNOG00000000532	Cmtr1	99	90.156	Rattus_norvegicus
ENSG00000137200	CMTR1	100	99.880	ENSRBIG00000027057	CMTR1	100	99.880	Rhinopithecus_bieti
ENSG00000137200	CMTR1	100	99.880	ENSRROG00000025840	CMTR1	100	99.880	Rhinopithecus_roxellana
ENSG00000137200	CMTR1	100	100.000	ENSSBOG00000031128	CMTR1	100	98.922	Saimiri_boliviensis_boliviensis
ENSG00000137200	CMTR1	99	91.566	ENSSHAG00000015917	CMTR1	99	84.652	Sarcophilus_harrisii
ENSG00000137200	CMTR1	99	71.942	ENSSFOG00015016868	cmtr1	99	72.542	Scleropages_formosus
ENSG00000137200	CMTR1	99	69.424	ENSSMAG00000014027	cmtr1	99	69.424	Scophthalmus_maximus
ENSG00000137200	CMTR1	93	75.862	ENSSDUG00000016830	cmtr1	99	69.544	Seriola_dumerili
ENSG00000137200	CMTR1	93	75.862	ENSSLDG00000006047	cmtr1	99	70.876	Seriola_lalandi_dorsalis
ENSG00000137200	CMTR1	92	93.056	ENSSARG00000005374	CMTR1	99	90.482	Sorex_araneus
ENSG00000137200	CMTR1	99	83.453	ENSSPUG00000017427	CMTR1	99	83.313	Sphenodon_punctatus
ENSG00000137200	CMTR1	93	76.552	ENSSPAG00000007506	cmtr1	99	70.012	Stegastes_partitus
ENSG00000137200	CMTR1	93	94.483	ENSSSCG00000001579	CMTR1	100	95.754	Sus_scrofa
ENSG00000137200	CMTR1	99	80.912	ENSTGUG00000007924	CMTR1	99	81.753	Taeniopygia_guttata
ENSG00000137200	CMTR1	93	75.172	ENSTRUG00000014780	cmtr1	99	69.193	Takifugu_rubripes
ENSG00000137200	CMTR1	77	66.959	ENSTNIG00000012235	cmtr1	100	70.495	Tetraodon_nigroviridis
ENSG00000137200	CMTR1	93	95.862	ENSTBEG00000012457	CMTR1	92	96.464	Tupaia_belangeri
ENSG00000137200	CMTR1	100	96.048	ENSTTRG00000002801	CMTR1	100	96.048	Tursiops_truncatus
ENSG00000137200	CMTR1	100	96.766	ENSUAMG00000027934	CMTR1	100	96.766	Ursus_americanus
ENSG00000137200	CMTR1	97	93.973	ENSUMAG00000009577	CMTR1	100	92.010	Ursus_maritimus
ENSG00000137200	CMTR1	100	78.972	ENSVPAG00000003389	CMTR1	100	86.591	Vicugna_pacos
ENSG00000137200	CMTR1	100	96.766	ENSVVUG00000026447	CMTR1	100	96.766	Vulpes_vulpes
ENSG00000137200	CMTR1	93	77.241	ENSXETG00000009964	cmtr1	99	67.900	Xenopus_tropicalis
ENSG00000137200	CMTR1	93	75.172	ENSXCOG00000004583	cmtr1	99	69.295	Xiphophorus_couchianus
ENSG00000137200	CMTR1	92	76.224	ENSXMAG00000007486	cmtr1	99	69.415	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity	21873635.	IBA	Function
GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity	20713356.21310715.	IDA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	21310715.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006370	7-methylguanosine mRNA capping	21873635.	IBA	Process
GO:0006370	7-methylguanosine mRNA capping	21310715.	IDA	Process
GO:0006370	7-methylguanosine mRNA capping	20713356.	IMP	Process
GO:0080009	mRNA methylation	20713356.	IDA	Process
GO:0097309	cap1 mRNA methylation	21873635.	IBA	Process
GO:0097309	cap1 mRNA methylation	21310715.	IDA	Process