EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000138050 (Gene tree)
Gene ID: 80745
Gene Symbol: THUMPD2
Alias: MGC2454|C2orf8
Full Name: THUMP domain containing 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 43,217 bases
Position: chr2:39,736,060-39,779,276
Accession: 14890
RBP type: canonical RBP
Summary: (THUMP Domain Containing 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA binding and methyltransferase activity. An important paralog of this gene is THUMPD3.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000423933	THUMP	PF02926.17	3.5e-07	1	1
ENSP00000423933	MTS	PF05175.14	9.9e-06	1	1
ENSP00000423933	UPF0020	PF01170.18	1.2e-25	1	1
ENSP00000423933	Methyltransf_31	PF13847.6	1.4e-09	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000530095	THUMPD2-207	662	-	-	- (aa)	-	-
ENST00000378727	THUMPD2-201	2089	-	ENSP00000368001	303 (aa)	-	Q9BTF0
ENST00000403537	THUMPD2-202	961	-	-	- (aa)	-	-
ENST00000531687	THUMPD2-209	230	-	-	- (aa)	-	-
ENST00000460072	THUMPD2-203	3148	-	-	- (aa)	-	-
ENST00000527689	THUMPD2-206	210	-	-	- (aa)	-	-
ENST00000530522	THUMPD2-208	1561	-	ENSP00000434844	88 (aa)	-	H0YE26
ENST00000510781	THUMPD2-205	996	-	ENSP00000426202	291 (aa)	-	H7C5V1
ENST00000505747	THUMPD2-204	1970	XM_011533119	ENSP00000423933	503 (aa)	XP_011531421	Q9BTF0

Gene Model

Click here to download ENSG00000138050's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000138050	Triglycerides	1.13278273006227E-7	17903299
ENSG00000138050	Atrial Natriuretic Factor	1.60565106145409E-22	17903293
ENSG00000138050	Echocardiography	1.52239438652088E-6	17903301
ENSG00000138050	Platelet Function Tests	2.4593100E-005	-
ENSG00000138050	Platelet Function Tests	8.9867582E-006	-
ENSG00000138050	Platelet Function Tests	1.0121200E-005	-
ENSG00000138050	Platelet Function Tests	1.3181600E-005	-
ENSG00000138050	Child Development Disorders, Pervasive	4.3000000E-005	-
ENSG00000138050	Asthma	6E-7	23829686

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000138050's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000138050	THUMPD2	78	50.725	ENSAPOG00000001802	-	69	42.857	Acanthochromis_polyacanthus
ENSG00000138050	THUMPD2	91	80.694	ENSAMEG00000008664	THUMPD2	99	80.694	Ailuropoda_melanoleuca
ENSG00000138050	THUMPD2	98	36.577	ENSACIG00000011677	THUMPD2	90	36.215	Amphilophus_citrinellus
ENSG00000138050	THUMPD2	90	46.835	ENSAOCG00000000927	THUMPD2	77	40.541	Amphiprion_ocellaris
ENSG00000138050	THUMPD2	90	46.835	ENSAPEG00000000981	thumpd2	99	32.328	Amphiprion_percula
ENSG00000138050	THUMPD2	72	56.250	ENSATEG00000012329	thumpd2	67	45.130	Anabas_testudineus
ENSG00000138050	THUMPD2	94	51.143	ENSAPLG00000008775	THUMPD2	99	51.245	Anas_platyrhynchos
ENSG00000138050	THUMPD2	92	49.587	ENSACAG00000000538	THUMPD2	97	49.587	Anolis_carolinensis
ENSG00000138050	THUMPD2	100	93.651	ENSANAG00000034298	THUMPD2	100	93.651	Aotus_nancymaae
ENSG00000138050	THUMPD2	92	45.679	ENSACLG00000025840	thumpd2	90	48.052	Astatotilapia_calliptera
ENSG00000138050	THUMPD2	84	51.351	ENSAMXG00000011080	thumpd2	99	34.661	Astyanax_mexicanus
ENSG00000138050	THUMPD2	100	74.754	ENSBTAG00000004722	THUMPD2	99	75.498	Bos_taurus
ENSG00000138050	THUMPD2	100	93.849	ENSCJAG00000014891	THUMPD2	100	93.849	Callithrix_jacchus
ENSG00000138050	THUMPD2	100	82.341	ENSCAFG00000006471	THUMPD2	100	82.341	Canis_familiaris
ENSG00000138050	THUMPD2	94	83.544	ENSCAFG00020021695	THUMPD2	100	83.544	Canis_lupus_dingo
ENSG00000138050	THUMPD2	99	75.896	ENSCHIG00000013921	THUMPD2	99	75.896	Capra_hircus
ENSG00000138050	THUMPD2	92	81.720	ENSTSYG00000010555	THUMPD2	99	81.463	Carlito_syrichta
ENSG00000138050	THUMPD2	88	89.610	ENSCPOG00000003368	THUMPD2	100	72.871	Cavia_porcellus
ENSG00000138050	THUMPD2	100	93.651	ENSCCAG00000034405	THUMPD2	100	93.651	Cebus_capucinus
ENSG00000138050	THUMPD2	100	95.040	ENSCATG00000012396	THUMPD2	100	95.620	Cercocebus_atys
ENSG00000138050	THUMPD2	89	89.744	ENSCLAG00000003029	THUMPD2	99	75.397	Chinchilla_lanigera
ENSG00000138050	THUMPD2	82	95.134	ENSCSAG00000012431	THUMPD2	100	95.134	Chlorocebus_sabaeus
ENSG00000138050	THUMPD2	74	79.204	ENSCHOG00000000360	THUMPD2	100	75.989	Choloepus_hoffmanni
ENSG00000138050	THUMPD2	100	58.835	ENSCPBG00000018272	THUMPD2	97	58.835	Chrysemys_picta_bellii
ENSG00000138050	THUMPD2	100	93.452	ENSCANG00000032596	THUMPD2	100	93.452	Colobus_angolensis_palliatus
ENSG00000138050	THUMPD2	100	71.032	ENSCGRG00001009939	Thumpd2	95	71.032	Cricetulus_griseus_chok1gshd
ENSG00000138050	THUMPD2	88	70.270	ENSCGRG00000006284	Thumpd2	94	70.270	Cricetulus_griseus_crigri
ENSG00000138050	THUMPD2	84	54.667	ENSCSEG00000000512	-	97	33.333	Cynoglossus_semilaevis
ENSG00000138050	THUMPD2	74	39.037	ENSCVAG00000007942	THUMPD2	80	40.374	Cyprinodon_variegatus
ENSG00000138050	THUMPD2	96	35.458	ENSDARG00000093070	thumpd2	98	36.585	Danio_rerio
ENSG00000138050	THUMPD2	98	80.847	ENSDNOG00000019834	THUMPD2	98	80.847	Dasypus_novemcinctus
ENSG00000138050	THUMPD2	91	64.565	ENSETEG00000001300	THUMPD2	99	64.565	Echinops_telfairi
ENSG00000138050	THUMPD2	56	41.237	ENSEBUG00000010906	THUMPD2	85	41.237	Eptatretus_burgeri
ENSG00000138050	THUMPD2	100	80.754	ENSEASG00005005106	THUMPD2	95	81.855	Equus_asinus_asinus
ENSG00000138050	THUMPD2	100	80.682	ENSECAG00000010799	THUMPD2	97	80.159	Equus_caballus
ENSG00000138050	THUMPD2	91	56.277	ENSEEUG00000000105	THUMPD2	100	56.277	Erinaceus_europaeus
ENSG00000138050	THUMPD2	96	37.475	ENSELUG00000003735	thumpd2	94	36.965	Esox_lucius
ENSG00000138050	THUMPD2	89	91.026	ENSFCAG00000006809	THUMPD2	100	78.770	Felis_catus
ENSG00000138050	THUMPD2	92	49.578	ENSFALG00000008655	THUMPD2	97	48.069	Ficedula_albicollis
ENSG00000138050	THUMPD2	97	35.782	ENSFHEG00000011402	thumpd2	97	35.782	Fundulus_heteroclitus
ENSG00000138050	THUMPD2	99	44.828	ENSGMOG00000002236	-	100	33.916	Gadus_morhua
ENSG00000138050	THUMPD2	82	51.659	ENSGALG00000009119	THUMPD2	99	51.659	Gallus_gallus
ENSG00000138050	THUMPD2	96	37.524	ENSGAFG00000012683	thumpd2	99	37.403	Gambusia_affinis
ENSG00000138050	THUMPD2	75	52.430	ENSGAGG00000001325	THUMPD2	98	52.430	Gopherus_agassizii
ENSG00000138050	THUMPD2	100	99.205	ENSGGOG00000001608	THUMPD2	100	99.205	Gorilla_gorilla
ENSG00000138050	THUMPD2	58	42.857	ENSHBUG00000011780	-	59	43.182	Haplochromis_burtoni
ENSG00000138050	THUMPD2	91	87.500	ENSHGLG00000019145	THUMPD2	99	76.786	Heterocephalus_glaber_female
ENSG00000138050	THUMPD2	88	42.400	ENSIPUG00000015283	thumpd2	97	42.400	Ictalurus_punctatus
ENSG00000138050	THUMPD2	100	80.754	ENSSTOG00000027472	THUMPD2	100	80.754	Ictidomys_tridecemlineatus
ENSG00000138050	THUMPD2	91	69.518	ENSJJAG00000020374	Thumpd2	97	69.518	Jaculus_jaculus
ENSG00000138050	THUMPD2	89	41.026	ENSLBEG00000007585	THUMPD2	83	39.610	Labrus_bergylta
ENSG00000138050	THUMPD2	96	41.517	ENSLOCG00000015747	THUMPD2	97	45.050	Lepisosteus_oculatus
ENSG00000138050	THUMPD2	99	79.070	ENSLAFG00000005383	-	99	79.070	Loxodonta_africana
ENSG00000138050	THUMPD2	100	94.841	ENSMFAG00000031464	THUMPD2	100	94.841	Macaca_fascicularis
ENSG00000138050	THUMPD2	100	95.040	ENSMMUG00000011841	THUMPD2	100	95.040	Macaca_mulatta
ENSG00000138050	THUMPD2	100	95.040	ENSMNEG00000037438	THUMPD2	100	95.040	Macaca_nemestrina
ENSG00000138050	THUMPD2	92	95.022	ENSMLEG00000031490	THUMPD2	100	95.022	Mandrillus_leucophaeus
ENSG00000138050	THUMPD2	98	33.779	ENSMAMG00000022090	thumpd2	83	38.221	Mastacembelus_armatus
ENSG00000138050	THUMPD2	95	45.238	ENSMZEG00005027354	-	67	43.506	Maylandia_zebra
ENSG00000138050	THUMPD2	94	53.445	ENSMGAG00000007605	THUMPD2	99	53.445	Meleagris_gallopavo
ENSG00000138050	THUMPD2	100	71.089	ENSMAUG00000012866	Thumpd2	95	71.089	Mesocricetus_auratus
ENSG00000138050	THUMPD2	97	86.299	ENSMICG00000008042	THUMPD2	100	85.516	Microcebus_murinus
ENSG00000138050	THUMPD2	100	69.246	ENSMOCG00000018094	Thumpd2	95	69.246	Microtus_ochrogaster
ENSG00000138050	THUMPD2	82	43.056	ENSMMOG00000007356	thumpd2	95	38.384	Mola_mola
ENSG00000138050	THUMPD2	92	65.733	ENSMODG00000009129	THUMPD2	100	66.164	Monodelphis_domestica
ENSG00000138050	THUMPD2	76	47.761	ENSMALG00000020471	thumpd2	99	32.283	Monopterus_albus
ENSG00000138050	THUMPD2	89	83.333	MGP_CAROLIEiJ_G0021912	Thumpd2	95	68.651	Mus_caroli
ENSG00000138050	THUMPD2	89	82.051	ENSMUSG00000024246	Thumpd2	95	68.651	Mus_musculus
ENSG00000138050	THUMPD2	88	81.818	MGP_PahariEiJ_G0020902	Thumpd2	95	68.254	Mus_pahari
ENSG00000138050	THUMPD2	89	82.051	MGP_SPRETEiJ_G0022828	Thumpd2	95	68.254	Mus_spretus
ENSG00000138050	THUMPD2	98	80.120	ENSMPUG00000010563	THUMPD2	98	80.120	Mustela_putorius_furo
ENSG00000138050	THUMPD2	94	80.591	ENSMLUG00000009688	THUMPD2	100	80.591	Myotis_lucifugus
ENSG00000138050	THUMPD2	99	71.856	ENSNGAG00000016396	Thumpd2	97	71.856	Nannospalax_galili
ENSG00000138050	THUMPD2	100	97.614	ENSNLEG00000016562	THUMPD2	100	97.614	Nomascus_leucogenys
ENSG00000138050	THUMPD2	94	62.368	ENSMEUG00000014815	THUMPD2	99	62.368	Notamacropus_eugenii
ENSG00000138050	THUMPD2	84	73.438	ENSOPRG00000013478	THUMPD2	99	65.727	Ochotona_princeps
ENSG00000138050	THUMPD2	89	47.436	ENSONIG00000001165	thumpd2	95	40.534	Oreochromis_niloticus
ENSG00000138050	THUMPD2	94	59.091	ENSOANG00000004028	-	97	60.497	Ornithorhynchus_anatinus
ENSG00000138050	THUMPD2	99	77.535	ENSOCUG00000003257	THUMPD2	100	80.101	Oryctolagus_cuniculus
ENSG00000138050	THUMPD2	98	36.770	ENSORLG00000002138	thumpd2	99	36.770	Oryzias_latipes
ENSG00000138050	THUMPD2	80	36.493	ENSORLG00020018792	thumpd2	96	36.493	Oryzias_latipes_hni
ENSG00000138050	THUMPD2	96	37.030	ENSORLG00015005237	thumpd2	97	36.759	Oryzias_latipes_hsok
ENSG00000138050	THUMPD2	94	36.513	ENSOMEG00000023563	thumpd2	97	34.749	Oryzias_melastigma
ENSG00000138050	THUMPD2	91	82.391	ENSOGAG00000010890	THUMPD2	99	82.391	Otolemur_garnettii
ENSG00000138050	THUMPD2	98	76.431	ENSOARG00000007841	THUMPD2	99	70.693	Ovis_aries
ENSG00000138050	THUMPD2	98	98.371	ENSPPAG00000033850	THUMPD2	100	98.371	Pan_paniscus
ENSG00000138050	THUMPD2	89	91.026	ENSPPRG00000003874	THUMPD2	100	79.167	Panthera_pardus
ENSG00000138050	THUMPD2	92	79.437	ENSPTIG00000004118	THUMPD2	96	79.437	Panthera_tigris_altaica
ENSG00000138050	THUMPD2	100	99.404	ENSPTRG00000011860	THUMPD2	100	99.404	Pan_troglodytes
ENSG00000138050	THUMPD2	100	94.048	ENSPANG00000004807	THUMPD2	100	94.048	Papio_anubis
ENSG00000138050	THUMPD2	96	37.449	ENSPKIG00000022207	THUMPD2	89	37.449	Paramormyrops_kingsleyae
ENSG00000138050	THUMPD2	92	57.569	ENSPSIG00000003159	THUMPD2	99	57.569	Pelodiscus_sinensis
ENSG00000138050	THUMPD2	89	81.013	ENSPEMG00000009015	Thumpd2	95	69.643	Peromyscus_maniculatus_bairdii
ENSG00000138050	THUMPD2	88	36.059	ENSPMAG00000006922	thumpd2	99	40.260	Petromyzon_marinus
ENSG00000138050	THUMPD2	89	76.923	ENSPCIG00000022621	THUMPD2	96	63.052	Phascolarctos_cinereus
ENSG00000138050	THUMPD2	99	36.538	ENSPFOG00000006461	thumpd2	99	36.762	Poecilia_formosa
ENSG00000138050	THUMPD2	99	33.399	ENSPLAG00000010700	THUMPD2	99	33.597	Poecilia_latipinna
ENSG00000138050	THUMPD2	99	36.364	ENSPMEG00000009573	-	99	36.595	Poecilia_mexicana
ENSG00000138050	THUMPD2	85	41.379	ENSPREG00000001603	THUMPD2	89	43.667	Poecilia_reticulata
ENSG00000138050	THUMPD2	94	97.257	ENSPPYG00000012470	THUMPD2	100	97.805	Pongo_abelii
ENSG00000138050	THUMPD2	92	63.341	ENSPCAG00000007326	THUMPD2	99	63.341	Procavia_capensis
ENSG00000138050	THUMPD2	97	87.090	ENSPCOG00000000396	-	100	86.508	Propithecus_coquereli
ENSG00000138050	THUMPD2	98	78.523	ENSPCOG00000028456	-	100	73.214	Propithecus_coquereli
ENSG00000138050	THUMPD2	94	80.591	ENSPVAG00000008101	THUMPD2	100	80.591	Pteropus_vampyrus
ENSG00000138050	THUMPD2	90	46.835	ENSPNYG00000009804	THUMPD2	97	30.039	Pundamilia_nyererei
ENSG00000138050	THUMPD2	97	37.323	ENSPNAG00000023224	thumpd2	98	37.323	Pygocentrus_nattereri
ENSG00000138050	THUMPD2	89	82.051	ENSRNOG00000008291	Thumpd2	90	67.337	Rattus_norvegicus
ENSG00000138050	THUMPD2	100	86.680	ENSRBIG00000034978	THUMPD2	100	86.680	Rhinopithecus_bieti
ENSG00000138050	THUMPD2	98	94.295	ENSRROG00000031707	THUMPD2	100	95.359	Rhinopithecus_roxellana
ENSG00000138050	THUMPD2	100	92.460	ENSSBOG00000015419	THUMPD2	100	92.460	Saimiri_boliviensis_boliviensis
ENSG00000138050	THUMPD2	94	66.173	ENSSHAG00000010785	THUMPD2	99	66.173	Sarcophilus_harrisii
ENSG00000138050	THUMPD2	80	57.143	ENSSFOG00015006959	THUMPD2	96	46.535	Scleropages_formosus
ENSG00000138050	THUMPD2	77	44.118	ENSSDUG00000019898	THUMPD2	68	40.968	Seriola_dumerili
ENSG00000138050	THUMPD2	77	44.118	ENSSLDG00000016788	-	80	40.968	Seriola_lalandi_dorsalis
ENSG00000138050	THUMPD2	82	53.012	ENSSPUG00000006316	THUMPD2	97	53.012	Sphenodon_punctatus
ENSG00000138050	THUMPD2	99	77.183	ENSSSCG00000008470	THUMPD2	98	77.935	Sus_scrofa
ENSG00000138050	THUMPD2	88	49.438	ENSTGUG00000012782	THUMPD2	100	56.041	Taeniopygia_guttata
ENSG00000138050	THUMPD2	96	36.187	ENSTRUG00000022712	THUMPD2	97	36.187	Takifugu_rubripes
ENSG00000138050	THUMPD2	88	35.075	ENSTNIG00000009817	-	100	35.075	Tetraodon_nigroviridis
ENSG00000138050	THUMPD2	54	64.599	ENSTBEG00000008269	-	59	64.599	Tupaia_belangeri
ENSG00000138050	THUMPD2	94	81.780	ENSTTRG00000005603	THUMPD2	99	81.780	Tursiops_truncatus
ENSG00000138050	THUMPD2	99	80.716	ENSUAMG00000011048	THUMPD2	97	80.716	Ursus_americanus
ENSG00000138050	THUMPD2	97	75.615	ENSUMAG00000013316	THUMPD2	95	78.355	Ursus_maritimus
ENSG00000138050	THUMPD2	88	76.779	ENSVPAG00000007570	THUMPD2	86	76.779	Vicugna_pacos
ENSG00000138050	THUMPD2	94	82.526	ENSVVUG00000018628	THUMPD2	100	82.526	Vulpes_vulpes
ENSG00000138050	THUMPD2	96	44.071	ENSXETG00000018494	thumpd2	99	44.664	Xenopus_tropicalis
ENSG00000138050	THUMPD2	83	44.444	ENSXCOG00000013456	-	91	44.803	Xiphophorus_couchianus
ENSG00000138050	THUMPD2	99	36.773	ENSXMAG00000017249	thumpd2	99	36.961	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	-	IEA	Function
GO:0016423	tRNA (guanine) methyltransferase activity	21873635.	IBA	Function
GO:0030488	tRNA methylation	21873635.	IBA	Process