EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000138399 (Gene tree)
Gene ID: 79675
Gene Symbol: FASTKD1
Alias: FLJ21901
Full Name: FAST kinase domains 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 46,042 bases
Position: chr2:169,527,880-169,573,921
Accession: 26150
RBP type: canonical RBP
Summary: (FAST Kinase Domains 1) is a Protein Coding gene. Diseases associated with FASTKD1 include Glaucoma 1, Open Angle, B. Gene Ontology (GO) annotations related to this gene include protein kinase activity. An important paralog of this gene is FASTKD3.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000403229	RAP	PF08373.10	4e-13	1	1
ENSP00000400513	RAP	PF08373.10	4.3e-13	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000490590	FASTKD1-209	493	-	-	- (aa)	-	-
ENST00000487293	FASTKD1-206	681	-	-	- (aa)	-	-
ENST00000453153	FASTKD1-204	2967	XM_006712750	ENSP00000400513	847 (aa)	XP_006712813	Q53R41
ENST00000488516	FASTKD1-207	468	-	-	- (aa)	-	-
ENST00000438035	FASTKD1-202	1045	-	ENSP00000396769	253 (aa)	-	E7EW60
ENST00000417376	FASTKD1-201	687	-	ENSP00000408667	104 (aa)	-	C9JMM4
ENST00000445210	FASTKD1-203	1850	-	ENSP00000399551	276 (aa)	-	C9JTP4
ENST00000495505	FASTKD1-210	591	-	-	- (aa)	-	-
ENST00000488951	FASTKD1-208	541	-	-	- (aa)	-	-
ENST00000453929	FASTKD1-205	2791	XM_017004912	ENSP00000403229	804 (aa)	XP_016860401	Q53R41

Gene Model

Click here to download ENSG00000138399's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000138399	Platelet Function Tests	1.2845000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000138399's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000138399	FASTKD1	98	45.718	ENSAPOG00000003378	fastkd1	99	45.718	Acanthochromis_polyacanthus
ENSG00000138399	FASTKD1	99	76.105	ENSAMEG00000010599	FASTKD1	99	76.105	Ailuropoda_melanoleuca
ENSG00000138399	FASTKD1	98	45.597	ENSAOCG00000002464	fastkd1	99	45.597	Amphiprion_ocellaris
ENSG00000138399	FASTKD1	98	45.838	ENSAPEG00000020266	fastkd1	99	45.838	Amphiprion_percula
ENSG00000138399	FASTKD1	98	44.604	ENSATEG00000017168	fastkd1	99	44.604	Anabas_testudineus
ENSG00000138399	FASTKD1	100	45.192	ENSAPLG00000006739	FASTKD1	100	46.163	Anas_platyrhynchos
ENSG00000138399	FASTKD1	98	48.197	ENSACAG00000017101	-	99	48.197	Anolis_carolinensis
ENSG00000138399	FASTKD1	100	90.385	ENSANAG00000026119	FASTKD1	100	88.207	Aotus_nancymaae
ENSG00000138399	FASTKD1	100	40.385	ENSACLG00000010999	fastkd1	97	47.273	Astatotilapia_calliptera
ENSG00000138399	FASTKD1	98	40.505	ENSAMXG00000005842	fastkd1	99	40.505	Astyanax_mexicanus
ENSG00000138399	FASTKD1	99	77.670	ENSBTAG00000010743	FASTKD1	100	76.082	Bos_taurus
ENSG00000138399	FASTKD1	100	90.385	ENSCJAG00000006566	FASTKD1	100	87.004	Callithrix_jacchus
ENSG00000138399	FASTKD1	99	78.641	ENSCAFG00000012344	FASTKD1	100	75.601	Canis_familiaris
ENSG00000138399	FASTKD1	99	78.641	ENSCAFG00020002841	FASTKD1	100	75.601	Canis_lupus_dingo
ENSG00000138399	FASTKD1	99	77.670	ENSCHIG00000016701	FASTKD1	100	76.202	Capra_hircus
ENSG00000138399	FASTKD1	100	68.269	ENSCPOG00000004972	FASTKD1	100	66.752	Cavia_porcellus
ENSG00000138399	FASTKD1	100	91.346	ENSCCAG00000031410	FASTKD1	99	87.831	Cebus_capucinus
ENSG00000138399	FASTKD1	100	92.029	ENSCATG00000031285	FASTKD1	100	91.006	Cercocebus_atys
ENSG00000138399	FASTKD1	100	69.231	ENSCLAG00000005581	FASTKD1	100	68.953	Chinchilla_lanigera
ENSG00000138399	FASTKD1	100	91.304	ENSCSAG00000015219	FASTKD1	100	88.402	Chlorocebus_sabaeus
ENSG00000138399	FASTKD1	69	72.632	ENSCHOG00000004746	-	59	80.287	Choloepus_hoffmanni
ENSG00000138399	FASTKD1	100	52.885	ENSCPBG00000006645	FASTKD1	99	54.106	Chrysemys_picta_bellii
ENSG00000138399	FASTKD1	100	88.462	ENSCANG00000024789	FASTKD1	99	91.099	Colobus_angolensis_palliatus
ENSG00000138399	FASTKD1	100	71.154	ENSCGRG00001022041	Fastkd1	100	70.468	Cricetulus_griseus_chok1gshd
ENSG00000138399	FASTKD1	100	71.154	ENSCGRG00000007662	Fastkd1	100	70.468	Cricetulus_griseus_crigri
ENSG00000138399	FASTKD1	98	39.568	ENSCSEG00000012089	fastkd1	100	39.568	Cynoglossus_semilaevis
ENSG00000138399	FASTKD1	98	45.608	ENSCVAG00000021458	fastkd1	99	45.608	Cyprinodon_variegatus
ENSG00000138399	FASTKD1	98	45.913	ENSDARG00000056128	fastkd1	99	45.913	Danio_rerio
ENSG00000138399	FASTKD1	98	75.933	ENSDNOG00000008867	FASTKD1	100	75.933	Dasypus_novemcinctus
ENSG00000138399	FASTKD1	100	69.231	ENSDORG00000023855	Fastkd1	100	68.269	Dipodomys_ordii
ENSG00000138399	FASTKD1	98	78.726	ENSEASG00005022845	FASTKD1	100	78.726	Equus_asinus_asinus
ENSG00000138399	FASTKD1	98	78.553	ENSECAG00000020558	FASTKD1	100	78.553	Equus_caballus
ENSG00000138399	FASTKD1	98	45.943	ENSELUG00000020744	fastkd1	99	45.943	Esox_lucius
ENSG00000138399	FASTKD1	99	80.583	ENSFCAG00000030802	FASTKD1	100	77.524	Felis_catus
ENSG00000138399	FASTKD1	98	46.386	ENSFALG00000000910	FASTKD1	99	46.386	Ficedula_albicollis
ENSG00000138399	FASTKD1	99	70.694	ENSFDAG00000009914	FASTKD1	100	70.694	Fukomys_damarensis
ENSG00000138399	FASTKD1	98	42.640	ENSFHEG00000023142	fastkd1	99	42.640	Fundulus_heteroclitus
ENSG00000138399	FASTKD1	100	35.577	ENSGMOG00000002850	fastkd1	87	47.181	Gadus_morhua
ENSG00000138399	FASTKD1	98	46.739	ENSGALG00000009841	FASTKD1	99	46.739	Gallus_gallus
ENSG00000138399	FASTKD1	96	43.780	ENSGAFG00000002575	fastkd1	98	45.335	Gambusia_affinis
ENSG00000138399	FASTKD1	99	43.042	ENSGACG00000005168	fastkd1	100	43.405	Gasterosteus_aculeatus
ENSG00000138399	FASTKD1	100	53.846	ENSGAGG00000016973	FASTKD1	99	54.348	Gopherus_agassizii
ENSG00000138399	FASTKD1	100	99.038	ENSGGOG00000016965	FASTKD1	100	94.333	Gorilla_gorilla
ENSG00000138399	FASTKD1	98	45.718	ENSHBUG00000006424	fastkd1	99	45.718	Haplochromis_burtoni
ENSG00000138399	FASTKD1	99	71.868	ENSHGLG00000008510	FASTKD1	99	71.868	Heterocephalus_glaber_female
ENSG00000138399	FASTKD1	99	71.749	ENSHGLG00100004453	FASTKD1	99	71.749	Heterocephalus_glaber_male
ENSG00000138399	FASTKD1	96	44.268	ENSHCOG00000018893	fastkd1	98	44.268	Hippocampus_comes
ENSG00000138399	FASTKD1	98	43.389	ENSIPUG00000010285	fastkd1	99	43.389	Ictalurus_punctatus
ENSG00000138399	FASTKD1	100	75.000	ENSSTOG00000011651	FASTKD1	100	76.923	Ictidomys_tridecemlineatus
ENSG00000138399	FASTKD1	100	64.423	ENSJJAG00000023087	Fastkd1	99	64.783	Jaculus_jaculus
ENSG00000138399	FASTKD1	98	43.541	ENSKMAG00000015786	fastkd1	100	43.541	Kryptolebias_marmoratus
ENSG00000138399	FASTKD1	98	45.324	ENSLBEG00000017104	fastkd1	99	45.324	Labrus_bergylta
ENSG00000138399	FASTKD1	100	49.038	ENSLACG00000012404	FASTKD1	99	48.379	Latimeria_chalumnae
ENSG00000138399	FASTKD1	98	48.255	ENSLOCG00000008010	fastkd1	99	48.255	Lepisosteus_oculatus
ENSG00000138399	FASTKD1	98	75.120	ENSLAFG00000016410	FASTKD1	100	75.120	Loxodonta_africana
ENSG00000138399	FASTKD1	100	92.029	ENSMFAG00000035847	FASTKD1	100	91.243	Macaca_fascicularis
ENSG00000138399	FASTKD1	100	92.754	ENSMMUG00000020511	FASTKD1	100	91.576	Macaca_mulatta
ENSG00000138399	FASTKD1	100	92.391	ENSMNEG00000043635	FASTKD1	100	91.124	Macaca_nemestrina
ENSG00000138399	FASTKD1	100	91.700	ENSMLEG00000023795	FASTKD1	100	88.402	Mandrillus_leucophaeus
ENSG00000138399	FASTKD1	98	47.002	ENSMAMG00000004655	fastkd1	100	47.002	Mastacembelus_armatus
ENSG00000138399	FASTKD1	100	40.385	ENSMZEG00005005844	fastkd1	97	47.273	Maylandia_zebra
ENSG00000138399	FASTKD1	100	45.667	ENSMGAG00000010393	FASTKD1	100	45.667	Meleagris_gallopavo
ENSG00000138399	FASTKD1	100	79.710	ENSMICG00000030856	FASTKD1	99	79.929	Microcebus_murinus
ENSG00000138399	FASTKD1	98	68.547	ENSMOCG00000006012	Fastkd1	100	68.547	Microtus_ochrogaster
ENSG00000138399	FASTKD1	98	43.608	ENSMMOG00000002104	fastkd1	100	43.608	Mola_mola
ENSG00000138399	FASTKD1	100	56.731	ENSMODG00000008073	FASTKD1	99	57.177	Monodelphis_domestica
ENSG00000138399	FASTKD1	98	43.285	ENSMALG00000007745	fastkd1	100	43.285	Monopterus_albus
ENSG00000138399	FASTKD1	100	69.231	MGP_CAROLIEiJ_G0023624	Fastkd1	100	69.231	Mus_caroli
ENSG00000138399	FASTKD1	100	68.269	ENSMUSG00000027086	Fastkd1	100	68.510	Mus_musculus
ENSG00000138399	FASTKD1	100	67.308	MGP_PahariEiJ_G0025076	Fastkd1	100	68.510	Mus_pahari
ENSG00000138399	FASTKD1	100	68.269	MGP_SPRETEiJ_G0024546	Fastkd1	100	69.111	Mus_spretus
ENSG00000138399	FASTKD1	99	76.699	ENSMPUG00000000777	FASTKD1	100	75.481	Mustela_putorius_furo
ENSG00000138399	FASTKD1	99	75.325	ENSMLUG00000003567	FASTKD1	99	75.325	Myotis_lucifugus
ENSG00000138399	FASTKD1	100	71.154	ENSNGAG00000013543	Fastkd1	100	68.630	Nannospalax_galili
ENSG00000138399	FASTKD1	98	45.597	ENSNBRG00000012972	fastkd1	99	45.597	Neolamprologus_brichardi
ENSG00000138399	FASTKD1	100	96.104	ENSNLEG00000004866	FASTKD1	100	96.104	Nomascus_leucogenys
ENSG00000138399	FASTKD1	100	59.615	ENSMEUG00000000438	-	74	61.667	Notamacropus_eugenii
ENSG00000138399	FASTKD1	99	70.874	ENSOPRG00000005401	FASTKD1	99	73.611	Ochotona_princeps
ENSG00000138399	FASTKD1	98	69.591	ENSODEG00000011766	FASTKD1	100	69.591	Octodon_degus
ENSG00000138399	FASTKD1	99	45.789	ENSONIG00000008787	fastkd1	99	45.789	Oreochromis_niloticus
ENSG00000138399	FASTKD1	98	75.841	ENSOCUG00000002198	FASTKD1	100	75.841	Oryctolagus_cuniculus
ENSG00000138399	FASTKD1	98	43.373	ENSORLG00000017160	fastkd1	100	43.373	Oryzias_latipes
ENSG00000138399	FASTKD1	98	43.494	ENSORLG00020022566	fastkd1	100	43.494	Oryzias_latipes_hni
ENSG00000138399	FASTKD1	98	42.212	ENSORLG00015016755	fastkd1	100	42.212	Oryzias_latipes_hsok
ENSG00000138399	FASTKD1	98	43.614	ENSOMEG00000003077	fastkd1	100	43.614	Oryzias_melastigma
ENSG00000138399	FASTKD1	99	78.081	ENSOGAG00000003722	FASTKD1	100	78.081	Otolemur_garnettii
ENSG00000138399	FASTKD1	99	78.641	ENSOARG00000003284	FASTKD1	99	75.598	Ovis_aries
ENSG00000138399	FASTKD1	100	100.000	ENSPPAG00000033920	FASTKD1	100	99.528	Pan_paniscus
ENSG00000138399	FASTKD1	99	80.583	ENSPPRG00000008130	FASTKD1	100	77.644	Panthera_pardus
ENSG00000138399	FASTKD1	99	80.583	ENSPTIG00000017377	FASTKD1	100	77.885	Panthera_tigris_altaica
ENSG00000138399	FASTKD1	100	100.000	ENSPTRG00000012616	FASTKD1	100	99.528	Pan_troglodytes
ENSG00000138399	FASTKD1	100	90.217	ENSPANG00000011789	FASTKD1	100	90.178	Papio_anubis
ENSG00000138399	FASTKD1	98	45.553	ENSPKIG00000003497	fastkd1	99	45.553	Paramormyrops_kingsleyae
ENSG00000138399	FASTKD1	86	51.176	ENSPMGG00000020008	fastkd1	99	51.268	Periophthalmus_magnuspinnatus
ENSG00000138399	FASTKD1	100	70.192	ENSPEMG00000023334	Fastkd1	100	69.628	Peromyscus_maniculatus_bairdii
ENSG00000138399	FASTKD1	97	31.938	ENSPMAG00000005599	fastkd1	98	31.938	Petromyzon_marinus
ENSG00000138399	FASTKD1	100	57.692	ENSPCIG00000026730	FASTKD1	100	58.213	Phascolarctos_cinereus
ENSG00000138399	FASTKD1	99	43.381	ENSPFOG00000009118	fastkd1	100	43.321	Poecilia_formosa
ENSG00000138399	FASTKD1	98	43.201	ENSPLAG00000000642	fastkd1	100	43.201	Poecilia_latipinna
ENSG00000138399	FASTKD1	98	43.442	ENSPMEG00000001059	fastkd1	100	43.442	Poecilia_mexicana
ENSG00000138399	FASTKD1	98	43.682	ENSPREG00000003336	fastkd1	100	43.682	Poecilia_reticulata
ENSG00000138399	FASTKD1	100	100.000	ENSPPYG00000012913	FASTKD1	98	96.805	Pongo_abelii
ENSG00000138399	FASTKD1	100	71.154	ENSPCAG00000015890	-	68	74.359	Procavia_capensis
ENSG00000138399	FASTKD1	99	81.455	ENSPCOG00000024955	FASTKD1	100	77.751	Propithecus_coquereli
ENSG00000138399	FASTKD1	99	77.670	ENSPVAG00000012734	FASTKD1	90	78.231	Pteropus_vampyrus
ENSG00000138399	FASTKD1	98	45.115	ENSPNYG00000006151	fastkd1	99	45.115	Pundamilia_nyererei
ENSG00000138399	FASTKD1	98	45.913	ENSPNAG00000002217	fastkd1	99	45.913	Pygocentrus_nattereri
ENSG00000138399	FASTKD1	100	66.346	ENSRNOG00000024335	Fastkd1	100	66.947	Rattus_norvegicus
ENSG00000138399	FASTKD1	100	92.391	ENSRBIG00000028416	FASTKD1	100	91.124	Rhinopithecus_bieti
ENSG00000138399	FASTKD1	100	92.391	ENSRROG00000045404	FASTKD1	100	91.243	Rhinopithecus_roxellana
ENSG00000138399	FASTKD1	100	87.500	ENSSBOG00000023109	FASTKD1	100	86.402	Saimiri_boliviensis_boliviensis
ENSG00000138399	FASTKD1	100	59.615	ENSSHAG00000017737	FASTKD1	100	57.177	Sarcophilus_harrisii
ENSG00000138399	FASTKD1	98	44.737	ENSSFOG00015022149	fastkd1	99	44.737	Scleropages_formosus
ENSG00000138399	FASTKD1	98	41.986	ENSSMAG00000013724	fastkd1	99	41.986	Scophthalmus_maximus
ENSG00000138399	FASTKD1	98	45.564	ENSSDUG00000020043	fastkd1	100	45.564	Seriola_dumerili
ENSG00000138399	FASTKD1	98	45.444	ENSSLDG00000003148	fastkd1	100	45.444	Seriola_lalandi_dorsalis
ENSG00000138399	FASTKD1	99	70.874	ENSSARG00000009332	FASTKD1	100	69.008	Sorex_araneus
ENSG00000138399	FASTKD1	98	44.337	ENSSPAG00000005563	fastkd1	100	44.337	Stegastes_partitus
ENSG00000138399	FASTKD1	98	45.783	ENSTGUG00000007867	FASTKD1	99	45.783	Taeniopygia_guttata
ENSG00000138399	FASTKD1	96	45.665	ENSTRUG00000017868	fastkd1	98	45.665	Takifugu_rubripes
ENSG00000138399	FASTKD1	98	45.803	ENSTNIG00000016922	fastkd1	100	45.803	Tetraodon_nigroviridis
ENSG00000138399	FASTKD1	100	78.846	ENSTBEG00000002127	FASTKD1	89	71.429	Tupaia_belangeri
ENSG00000138399	FASTKD1	99	77.670	ENSTTRG00000002137	FASTKD1	76	77.665	Tursiops_truncatus
ENSG00000138399	FASTKD1	99	76.699	ENSUAMG00000018993	FASTKD1	99	75.355	Ursus_americanus
ENSG00000138399	FASTKD1	99	75.728	ENSUMAG00000013794	FASTKD1	100	75.692	Ursus_maritimus
ENSG00000138399	FASTKD1	99	80.583	ENSVPAG00000007171	FASTKD1	89	84.348	Vicugna_pacos
ENSG00000138399	FASTKD1	99	79.612	ENSVVUG00000016627	FASTKD1	100	75.481	Vulpes_vulpes
ENSG00000138399	FASTKD1	100	46.154	ENSXETG00000018929	fastkd1	99	47.222	Xenopus_tropicalis
ENSG00000138399	FASTKD1	98	43.682	ENSXMAG00000014336	fastkd1	100	43.682	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000959	mitochondrial RNA metabolic process	28335001.	IMP	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0004672	protein kinase activity	-	IEA	Function
GO:0005739	mitochondrion	20869947.28335001.	IDA	Component
GO:0006468	protein phosphorylation	-	IEA	Process
GO:0044528	regulation of mitochondrial mRNA stability	28335001.	IMP	Process
GO:0045333	cellular respiration	20869947.	ISS	Process