EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000138617 (Gene tree)
Gene ID: 54956
Gene Symbol: PARP16
Alias: FLJ20509|FLJ25281|pART15|C15orf30
Full Name: poly(ADP-ribose) polymerase family member 16
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 66,159 bases
Position: chr15:65,234,460-65,300,618
Accession: 26040
RBP type: canonical RBP
Summary: PARP16 (Poly(ADP-Ribose) Polymerase Family Member 16) is a Protein Coding gene. Among its related pathways are Metabolism of water-soluble vitamins and cofactors and Apoptosis Modulation and Signaling. Gene Ontology (GO) annotations related to this gene include kinase binding and protein serine/threonine kinase activator activity. An important paralog of this gene is PARP8.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000496935	PARP	PF00644.20	7e-33	1	1
ENSP00000261888	PARP	PF00644.20	7.1e-33	1	1
ENSP00000396118	PARP	PF00644.20	4.8e-15	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000558873	PARP16-203	838	-	-	- (aa)	-	-
ENST00000444347	PARP16-202	2352	-	ENSP00000396118	207 (aa)	-	Q8N5Y8
ENST00000261888	PARP16-201	2731	XM_006720589	ENSP00000261888	323 (aa)	XP_006720652	Q8N5Y8
ENST00000649807	PARP16-206	2343	XM_006720590	ENSP00000496935	322 (aa)	XP_006720653	UPI0000141647
ENST00000560149	PARP16-205	823	-	-	- (aa)	-	-
ENST00000559805	PARP16-204	678	-	ENSP00000457982	72 (aa)	-	H3BV75

Gene Model

Click here to download ENSG00000138617's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000138617's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000138617	PARP16	93	70.455	ENSAPOG00000011225	parp16	94	61.736	Acanthochromis_polyacanthus
ENSG00000138617	PARP16	99	93.333	ENSAMEG00000002861	PARP16	86	90.625	Ailuropoda_melanoleuca
ENSG00000138617	PARP16	93	72.727	ENSACIG00000017326	parp16	94	62.379	Amphilophus_citrinellus
ENSG00000138617	PARP16	93	70.455	ENSAOCG00000007399	parp16	84	61.736	Amphiprion_ocellaris
ENSG00000138617	PARP16	84	52.574	ENSAOCG00000001382	-	82	52.574	Amphiprion_ocellaris
ENSG00000138617	PARP16	81	53.612	ENSAOCG00000011431	-	80	53.612	Amphiprion_ocellaris
ENSG00000138617	PARP16	93	70.455	ENSAPEG00000000410	parp16	94	61.736	Amphiprion_percula
ENSG00000138617	PARP16	70	75.248	ENSAPEG00000005885	-	83	62.500	Amphiprion_percula
ENSG00000138617	PARP16	100	69.333	ENSATEG00000015087	parp16	100	61.934	Anabas_testudineus
ENSG00000138617	PARP16	88	83.784	ENSAPLG00000015958	PARP16	92	74.247	Anas_platyrhynchos
ENSG00000138617	PARP16	94	69.388	ENSACAG00000004437	-	97	64.103	Anolis_carolinensis
ENSG00000138617	PARP16	100	97.101	ENSANAG00000026820	PARP16	100	97.987	Aotus_nancymaae
ENSG00000138617	PARP16	93	68.182	ENSACLG00000006576	parp16	94	61.812	Astatotilapia_calliptera
ENSG00000138617	PARP16	93	72.093	ENSAMXG00000037093	parp16	100	58.006	Astyanax_mexicanus
ENSG00000138617	PARP16	100	95.302	ENSBTAG00000012352	PARP16	100	92.547	Bos_taurus
ENSG00000138617	PARP16	100	98.137	ENSCJAG00000006929	PARP16	100	98.137	Callithrix_jacchus
ENSG00000138617	PARP16	100	93.960	ENSCAFG00000017142	PARP16	100	91.950	Canis_familiaris
ENSG00000138617	PARP16	92	92.617	ENSCAFG00020008773	PARP16	100	92.617	Canis_lupus_dingo
ENSG00000138617	PARP16	100	95.973	ENSCHIG00000011861	PARP16	100	92.857	Capra_hircus
ENSG00000138617	PARP16	95	82.736	ENSTSYG00000006046	PARP16	95	92.830	Carlito_syrichta
ENSG00000138617	PARP16	74	96.226	ENSCAPG00000013008	PARP16	100	94.954	Cavia_aperea
ENSG00000138617	PARP16	100	95.302	ENSCPOG00000025232	PARP16	100	91.615	Cavia_porcellus
ENSG00000138617	PARP16	100	97.333	ENSCCAG00000032095	PARP16	100	97.987	Cebus_capucinus
ENSG00000138617	PARP16	100	100.000	ENSCATG00000029968	PARP16	100	100.000	Cercocebus_atys
ENSG00000138617	PARP16	96	95.302	ENSCLAG00000012092	PARP16	100	92.652	Chinchilla_lanigera
ENSG00000138617	PARP16	99	98.592	ENSCSAG00000012842	PARP16	99	99.672	Chlorocebus_sabaeus
ENSG00000138617	PARP16	94	76.712	ENSCPBG00000014669	PARP16	94	73.871	Chrysemys_picta_bellii
ENSG00000138617	PARP16	95	41.925	ENSCING00000008693	-	98	41.925	Ciona_intestinalis
ENSG00000138617	PARP16	90	52.273	ENSCSAVG00000002311	-	97	42.628	Ciona_savignyi
ENSG00000138617	PARP16	100	99.329	ENSCANG00000034719	PARP16	100	99.329	Colobus_angolensis_palliatus
ENSG00000138617	PARP16	100	94.631	ENSCGRG00001011381	Parp16	100	90.373	Cricetulus_griseus_chok1gshd
ENSG00000138617	PARP16	93	91.304	ENSCGRG00000016969	Parp16	100	90.373	Cricetulus_griseus_crigri
ENSG00000138617	PARP16	93	70.455	ENSCSEG00000012872	parp16	94	62.821	Cynoglossus_semilaevis
ENSG00000138617	PARP16	92	64.179	ENSCVAG00000008328	parp16	94	51.282	Cyprinodon_variegatus
ENSG00000138617	PARP16	100	66.000	ENSDARG00000018593	parp16	100	61.027	Danio_rerio
ENSG00000138617	PARP16	100	96.644	ENSDNOG00000004137	PARP16	81	93.789	Dasypus_novemcinctus
ENSG00000138617	PARP16	96	91.290	ENSDORG00000028265	Parp16	98	91.139	Dipodomys_ordii
ENSG00000138617	PARP16	82	92.453	ENSETEG00000012936	PARP16	100	92.453	Echinops_telfairi
ENSG00000138617	PARP16	94	55.714	ENSEBUG00000001358	parp16	82	51.587	Eptatretus_burgeri
ENSG00000138617	PARP16	100	95.973	ENSEASG00005006476	PARP16	100	94.099	Equus_asinus_asinus
ENSG00000138617	PARP16	100	95.973	ENSECAG00000011251	PARP16	100	93.789	Equus_caballus
ENSG00000138617	PARP16	93	68.000	ENSELUG00000005526	parp16	94	62.179	Esox_lucius
ENSG00000138617	PARP16	100	96.000	ENSFCAG00000011463	PARP16	100	96.644	Felis_catus
ENSG00000138617	PARP16	92	81.818	ENSFALG00000010108	PARP16	98	73.115	Ficedula_albicollis
ENSG00000138617	PARP16	90	93.103	ENSFDAG00000016096	PARP16	100	93.103	Fukomys_damarensis
ENSG00000138617	PARP16	100	67.333	ENSFHEG00000009652	parp16	98	62.112	Fundulus_heteroclitus
ENSG00000138617	PARP16	94	68.613	ENSGMOG00000018820	parp16	99	60.635	Gadus_morhua
ENSG00000138617	PARP16	95	73.973	ENSGALG00000007365	PARP16	96	70.701	Gallus_gallus
ENSG00000138617	PARP16	93	72.727	ENSGAFG00000014534	parp16	94	61.538	Gambusia_affinis
ENSG00000138617	PARP16	93	70.455	ENSGACG00000006315	parp16	94	61.812	Gasterosteus_aculeatus
ENSG00000138617	PARP16	94	76.027	ENSGAGG00000005709	PARP16	94	73.548	Gopherus_agassizii
ENSG00000138617	PARP16	100	100.000	ENSGGOG00000022851	PARP16	100	100.000	Gorilla_gorilla
ENSG00000138617	PARP16	93	68.182	ENSHBUG00000003280	parp16	94	61.812	Haplochromis_burtoni
ENSG00000138617	PARP16	100	93.960	ENSHGLG00000010657	PARP16	100	89.752	Heterocephalus_glaber_female
ENSG00000138617	PARP16	100	93.960	ENSHGLG00100018347	PARP16	100	89.752	Heterocephalus_glaber_male
ENSG00000138617	PARP16	92	69.388	ENSHCOG00000017214	parp16	93	62.092	Hippocampus_comes
ENSG00000138617	PARP16	92	73.171	ENSIPUG00000020282	parp16	93	61.364	Ictalurus_punctatus
ENSG00000138617	PARP16	100	95.973	ENSSTOG00000008979	PARP16	100	93.168	Ictidomys_tridecemlineatus
ENSG00000138617	PARP16	82	88.636	ENSJJAG00000019303	Parp16	100	88.636	Jaculus_jaculus
ENSG00000138617	PARP16	93	75.556	ENSKMAG00000000762	parp16	94	62.939	Kryptolebias_marmoratus
ENSG00000138617	PARP16	92	68.919	ENSLBEG00000013968	parp16	94	57.325	Labrus_bergylta
ENSG00000138617	PARP16	92	75.000	ENSLACG00000016410	PARP16	93	71.242	Latimeria_chalumnae
ENSG00000138617	PARP16	98	72.789	ENSLOCG00000013778	parp16	95	64.396	Lepisosteus_oculatus
ENSG00000138617	PARP16	100	96.552	ENSLAFG00000014938	PARP16	71	95.031	Loxodonta_africana
ENSG00000138617	PARP16	100	100.000	ENSMFAG00000036137	PARP16	100	94.099	Macaca_fascicularis
ENSG00000138617	PARP16	100	100.000	ENSMMUG00000005749	PARP16	100	100.000	Macaca_mulatta
ENSG00000138617	PARP16	100	100.000	ENSMNEG00000028481	PARP16	100	100.000	Macaca_nemestrina
ENSG00000138617	PARP16	93	100.000	ENSMLEG00000035171	PARP16	100	100.000	Mandrillus_leucophaeus
ENSG00000138617	PARP16	93	68.182	ENSMAMG00000001037	parp16	94	62.179	Mastacembelus_armatus
ENSG00000138617	PARP16	93	68.182	ENSMZEG00005004556	parp16	94	61.812	Maylandia_zebra
ENSG00000138617	PARP16	93	70.149	ENSMGAG00000009579	PARP16	98	71.264	Meleagris_gallopavo
ENSG00000138617	PARP16	93	93.960	ENSMAUG00000014432	Parp16	100	90.062	Mesocricetus_auratus
ENSG00000138617	PARP16	100	98.000	ENSMICG00000004993	PARP16	100	98.658	Microcebus_murinus
ENSG00000138617	PARP16	95	91.176	ENSMOCG00000014635	Parp16	99	90.343	Microtus_ochrogaster
ENSG00000138617	PARP16	93	68.182	ENSMMOG00000012735	parp16	94	61.859	Mola_mola
ENSG00000138617	PARP16	99	80.952	ENSMODG00000010285	PARP16	98	78.438	Monodelphis_domestica
ENSG00000138617	PARP16	93	68.182	ENSMALG00000008263	parp16	94	61.859	Monopterus_albus
ENSG00000138617	PARP16	100	90.604	MGP_CAROLIEiJ_G0032354	Parp16	100	89.752	Mus_caroli
ENSG00000138617	PARP16	100	91.946	ENSMUSG00000032392	Parp16	100	90.373	Mus_musculus
ENSG00000138617	PARP16	100	92.617	MGP_PahariEiJ_G0015219	Parp16	100	90.683	Mus_pahari
ENSG00000138617	PARP16	100	91.946	MGP_SPRETEiJ_G0033493	Parp16	100	90.373	Mus_spretus
ENSG00000138617	PARP16	100	92.617	ENSMPUG00000000505	PARP16	100	92.260	Mustela_putorius_furo
ENSG00000138617	PARP16	100	95.973	ENSMLUG00000008817	-	96	92.857	Myotis_lucifugus
ENSG00000138617	PARP16	100	93.289	ENSMLUG00000027763	-	91	89.752	Myotis_lucifugus
ENSG00000138617	PARP16	100	92.617	ENSNGAG00000004884	Parp16	100	91.925	Nannospalax_galili
ENSG00000138617	PARP16	93	68.182	ENSNBRG00000002822	parp16	94	61.812	Neolamprologus_brichardi
ENSG00000138617	PARP16	100	99.517	ENSNLEG00000012643	-	100	100.000	Nomascus_leucogenys
ENSG00000138617	PARP16	99	81.081	ENSMEUG00000001881	PARP16	98	79.751	Notamacropus_eugenii
ENSG00000138617	PARP16	82	91.667	ENSOPRG00000010193	PARP16	100	95.890	Ochotona_princeps
ENSG00000138617	PARP16	100	95.302	ENSODEG00000016601	PARP16	100	91.615	Octodon_degus
ENSG00000138617	PARP16	93	68.182	ENSONIG00000008404	parp16	94	61.812	Oreochromis_niloticus
ENSG00000138617	PARP16	99	67.606	ENSOANG00000008180	PARP16	99	71.374	Ornithorhynchus_anatinus
ENSG00000138617	PARP16	100	95.666	ENSOCUG00000007306	PARP16	99	95.666	Oryctolagus_cuniculus
ENSG00000138617	PARP16	93	70.455	ENSORLG00000004989	parp16	94	61.489	Oryzias_latipes
ENSG00000138617	PARP16	93	70.455	ENSORLG00020012000	parp16	94	61.165	Oryzias_latipes_hni
ENSG00000138617	PARP16	93	70.455	ENSORLG00015005215	parp16	94	61.489	Oryzias_latipes_hsok
ENSG00000138617	PARP16	93	67.391	ENSOMEG00000014528	parp16	94	62.783	Oryzias_melastigma
ENSG00000138617	PARP16	100	98.000	ENSOGAG00000013641	PARP16	91	87.926	Otolemur_garnettii
ENSG00000138617	PARP16	100	95.973	ENSOARG00000017858	PARP16	99	92.857	Ovis_aries
ENSG00000138617	PARP16	100	100.000	ENSPPAG00000030232	PARP16	100	100.000	Pan_paniscus
ENSG00000138617	PARP16	100	96.667	ENSPPRG00000022890	PARP16	100	97.315	Panthera_pardus
ENSG00000138617	PARP16	99	94.366	ENSPTIG00000004433	PARP16	99	97.315	Panthera_tigris_altaica
ENSG00000138617	PARP16	100	100.000	ENSPTRG00000007178	PARP16	100	100.000	Pan_troglodytes
ENSG00000138617	PARP16	100	100.000	ENSPANG00000016725	PARP16	100	100.000	Papio_anubis
ENSG00000138617	PARP16	96	68.667	ENSPKIG00000015906	parp16	96	61.270	Paramormyrops_kingsleyae
ENSG00000138617	PARP16	99	76.027	ENSPSIG00000013215	PARP16	98	71.827	Pelodiscus_sinensis
ENSG00000138617	PARP16	93	70.455	ENSPMGG00000006621	parp16	94	62.783	Periophthalmus_magnuspinnatus
ENSG00000138617	PARP16	100	93.289	ENSPEMG00000022071	Parp16	100	90.994	Peromyscus_maniculatus_bairdii
ENSG00000138617	PARP16	95	62.329	ENSPMAG00000000919	parp16	97	58.917	Petromyzon_marinus
ENSG00000138617	PARP16	92	84.091	ENSPCIG00000024110	PARP16	98	79.012	Phascolarctos_cinereus
ENSG00000138617	PARP16	93	72.727	ENSPFOG00000003537	parp16	94	62.179	Poecilia_formosa
ENSG00000138617	PARP16	93	72.727	ENSPLAG00000009118	parp16	94	62.179	Poecilia_latipinna
ENSG00000138617	PARP16	93	70.455	ENSPMEG00000016623	parp16	94	61.859	Poecilia_mexicana
ENSG00000138617	PARP16	93	72.727	ENSPREG00000015760	parp16	94	60.897	Poecilia_reticulata
ENSG00000138617	PARP16	100	98.762	ENSPPYG00000006565	PARP16	100	98.762	Pongo_abelii
ENSG00000138617	PARP16	100	94.828	ENSPCAG00000003599	PARP16	100	92.570	Procavia_capensis
ENSG00000138617	PARP16	100	98.667	ENSPCOG00000019309	PARP16	100	99.329	Propithecus_coquereli
ENSG00000138617	PARP16	100	87.931	ENSPVAG00000004875	PARP16	100	79.876	Pteropus_vampyrus
ENSG00000138617	PARP16	93	68.182	ENSPNYG00000021598	parp16	94	61.812	Pundamilia_nyererei
ENSG00000138617	PARP16	93	72.093	ENSPNAG00000016973	parp16	87	58.805	Pygocentrus_nattereri
ENSG00000138617	PARP16	100	91.275	ENSRNOG00000029127	Parp16	76	89.130	Rattus_norvegicus
ENSG00000138617	PARP16	100	99.329	ENSRBIG00000040761	PARP16	100	99.329	Rhinopithecus_bieti
ENSG00000138617	PARP16	100	99.071	ENSRROG00000043358	PARP16	100	99.329	Rhinopithecus_roxellana
ENSG00000138617	PARP16	100	96.635	ENSSBOG00000032698	PARP16	100	97.333	Saimiri_boliviensis_boliviensis
ENSG00000138617	PARP16	99	82.313	ENSSHAG00000012032	PARP16	98	79.375	Sarcophilus_harrisii
ENSG00000138617	PARP16	93	70.667	ENSSFOG00015015435	parp16	93	64.630	Scleropages_formosus
ENSG00000138617	PARP16	93	68.182	ENSSMAG00000010948	parp16	81	61.859	Scophthalmus_maximus
ENSG00000138617	PARP16	92	68.657	ENSSDUG00000021721	parp16	92	63.696	Seriola_dumerili
ENSG00000138617	PARP16	93	70.455	ENSSLDG00000007648	parp16	94	63.462	Seriola_lalandi_dorsalis
ENSG00000138617	PARP16	50	83.478	ENSSARG00000008852	-	60	83.478	Sorex_araneus
ENSG00000138617	PARP16	99	74.150	ENSSPUG00000009787	PARP16	98	70.245	Sphenodon_punctatus
ENSG00000138617	PARP16	92	70.455	ENSSPAG00000001323	parp16	91	61.688	Stegastes_partitus
ENSG00000138617	PARP16	100	97.987	ENSSSCG00000004929	PARP16	100	95.342	Sus_scrofa
ENSG00000138617	PARP16	92	69.595	ENSTGUG00000009103	PARP16	99	69.595	Taeniopygia_guttata
ENSG00000138617	PARP16	93	72.727	ENSTRUG00000006022	parp16	94	58.879	Takifugu_rubripes
ENSG00000138617	PARP16	100	68.000	ENSTNIG00000013709	parp16	100	60.671	Tetraodon_nigroviridis
ENSG00000138617	PARP16	82	93.333	ENSTBEG00000010101	PARP16	100	92.453	Tupaia_belangeri
ENSG00000138617	PARP16	93	95.588	ENSTTRG00000005004	PARP16	100	95.094	Tursiops_truncatus
ENSG00000138617	PARP16	99	91.946	ENSUAMG00000016988	PARP16	99	91.875	Ursus_americanus
ENSG00000138617	PARP16	99	87.324	ENSUMAG00000012504	PARP16	100	92.333	Ursus_maritimus
ENSG00000138617	PARP16	82	93.333	ENSVPAG00000008504	PARP16	74	97.333	Vicugna_pacos
ENSG00000138617	PARP16	94	92.787	ENSVVUG00000014214	PARP16	100	92.787	Vulpes_vulpes
ENSG00000138617	PARP16	97	68.027	ENSXETG00000006648	parp16	87	64.038	Xenopus_tropicalis
ENSG00000138617	PARP16	93	72.727	ENSXCOG00000016475	parp16	94	57.622	Xiphophorus_couchianus
ENSG00000138617	PARP16	93	72.727	ENSXMAG00000007454	parp16	93	61.538	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003950	NAD+ ADP-ribosyltransferase activity	21873635.	IBA	Function
GO:0003950	NAD+ ADP-ribosyltransferase activity	22701565.23103912.	IMP	Function
GO:0005515	protein binding	22701565.25416956.	IPI	Function
GO:0005635	nuclear envelope	21873635.	IBA	Component
GO:0005635	nuclear envelope	22701565.	IDA	Component
GO:0005783	endoplasmic reticulum	21873635.	IBA	Component
GO:0005783	endoplasmic reticulum	23103912.	IMP	Component
GO:0005789	endoplasmic reticulum membrane	-	IEA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006471	protein ADP-ribosylation	21873635.	IBA	Process
GO:0006471	protein ADP-ribosylation	22701565.23103912.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0019900	kinase binding	21873635.	IBA	Function
GO:0019900	kinase binding	23103912.	IPI	Function
GO:0030968	endoplasmic reticulum unfolded protein response	21873635.	IBA	Process
GO:0030968	endoplasmic reticulum unfolded protein response	23103912.	IMP	Process
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	-	TAS	Process
GO:0036498	IRE1-mediated unfolded protein response	23103912.	IMP	Process
GO:0043539	protein serine/threonine kinase activator activity	21873635.	IBA	Function
GO:0043539	protein serine/threonine kinase activator activity	23103912.	IMP	Function
GO:0060548	negative regulation of cell death	23103912.	IMP	Process
GO:0070213	protein auto-ADP-ribosylation	25043379.	IDA	Process
GO:0070213	protein auto-ADP-ribosylation	22701565.23103912.	IMP	Process
GO:0071782	endoplasmic reticulum tubular network	21873635.	IBA	Component
GO:0071782	endoplasmic reticulum tubular network	22701565.	IMP	Component
GO:0071902	positive regulation of protein serine/threonine kinase activity	23103912.	IMP	Process
GO:1990404	protein ADP-ribosylase activity	25043379.	IDA	Function
GO:1990830	cellular response to leukemia inhibitory factor	-	IEA	Process