EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000138709 (Gene tree)
Gene ID: 55132
Gene Symbol: LARP1B
Alias: FLJ10378|DKFZp434K245|DKFZp686E0316|LARP2
Full Name: La ribonucleoprotein domain family member 1B
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 161,666 bases
Position: chr4:128,061,266-128,222,931
Accession: 24704
RBP type: canonical RBP
Summary: This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000377829	La	PF05383.17	1.1e-21	1	1
ENSP00000390395	La	PF05383.17	1.3e-21	1	1
ENSP00000424383	La	PF05383.17	2.1e-21	1	1
ENSP00000422850	La	PF05383.17	2.5e-21	1	1
ENSP00000321997	La	PF05383.17	2.8e-21	1	1
ENSP00000497514	La	PF05383.17	3e-21	1	1
ENSP00000497312	La	PF05383.17	3.2e-21	1	1
ENSP00000497192	La	PF05383.17	4.4e-21	1	1
ENSP00000427281	La	PF05383.17	5.7e-21	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000507259	LARP1B-206	1513	-	ENSP00000423686	25 (aa)	-	H0Y9B4
ENST00000508648	LARP1B-208	1104	-	-	- (aa)	-	-
ENST00000506199	LARP1B-205	1412	-	-	- (aa)	-	-
ENST00000507377	LARP1B-207	1593	-	ENSP00000424383	491 (aa)	-	H0Y9K3
ENST00000394288	LARP1B-202	2151	XM_017008353	ENSP00000377829	335 (aa)	XP_016863842	Q659C4
ENST00000648358	LARP1B-211	2563	XM_017008352	ENSP00000497514	536 (aa)	XP_016863841	UPI000387DF46
ENST00000649983	LARP1B-212	4606	XM_011532057	ENSP00000497192	1115 (aa)	XP_011530359	UPI0007DC57B6
ENST00000650359	LARP1B-213	3139	XM_011532072	ENSP00000497312	559 (aa)	XP_011530374	-
ENST00000512292	LARP1B-210	3105	XM_017008348	ENSP00000422850	518 (aa)	XP_016863837	D6R9W6
ENST00000508819	LARP1B-209	1891	-	ENSP00000427281	574 (aa)	-	D6RJB0
ENST00000503725	LARP1B-204	1181	-	-	- (aa)	-	-
ENST00000326639	LARP1B-201	4891	XM_011532067	ENSP00000321997	914 (aa)	XP_011530369	Q659C4
ENST00000432347	LARP1B-203	2707	-	ENSP00000390395	358 (aa)	-	G3V0E9

Gene Model

Click here to download ENSG00000138709's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000138709's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000138709	LARP1B	96	59.670	ENSG00000155506	LARP1	99	54.355

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000138709	LARP1B	97	56.742	ENSAPOG00000020101	larp1b	88	55.388	Acanthochromis_polyacanthus
ENSG00000138709	LARP1B	96	95.833	ENSAMEG00000002748	LARP1B	100	91.642	Ailuropoda_melanoleuca
ENSG00000138709	LARP1B	99	52.397	ENSACIG00000023890	larp1b	86	52.658	Amphilophus_citrinellus
ENSG00000138709	LARP1B	99	52.676	ENSAOCG00000014268	larp1b	88	53.080	Amphiprion_ocellaris
ENSG00000138709	LARP1B	98	57.375	ENSAPEG00000004126	larp1b	88	56.155	Amphiprion_percula
ENSG00000138709	LARP1B	99	56.124	ENSATEG00000017849	larp1b	89	55.176	Anabas_testudineus
ENSG00000138709	LARP1B	98	67.793	ENSAPLG00000010129	LARP1B	100	67.996	Anas_platyrhynchos
ENSG00000138709	LARP1B	98	74.319	ENSACAG00000011338	LARP1B	88	76.077	Anolis_carolinensis
ENSG00000138709	LARP1B	96	100.000	ENSANAG00000034618	LARP1B	100	78.151	Aotus_nancymaae
ENSG00000138709	LARP1B	96	56.460	ENSACLG00000011948	larp1b	87	55.410	Astatotilapia_calliptera
ENSG00000138709	LARP1B	100	50.242	ENSAMXG00000006805	larp1b	89	50.681	Astyanax_mexicanus
ENSG00000138709	LARP1B	100	92.000	ENSBTAG00000012135	LARP1B	98	89.442	Bos_taurus
ENSG00000138709	LARP1B	96	100.000	ENSCJAG00000003338	LARP1B	100	95.946	Callithrix_jacchus
ENSG00000138709	LARP1B	96	95.833	ENSCAFG00000003831	LARP1B	100	90.949	Canis_familiaris
ENSG00000138709	LARP1B	100	92.239	ENSCAFG00020018899	LARP1B	100	92.239	Canis_lupus_dingo
ENSG00000138709	LARP1B	100	92.000	ENSCHIG00000023144	LARP1B	100	89.286	Capra_hircus
ENSG00000138709	LARP1B	98	85.106	ENSTSYG00000002037	-	98	87.234	Carlito_syrichta
ENSG00000138709	LARP1B	76	91.964	ENSCPOG00000034668	-	93	91.964	Cavia_porcellus
ENSG00000138709	LARP1B	100	96.525	ENSCCAG00000021948	LARP1B	100	96.525	Cebus_capucinus
ENSG00000138709	LARP1B	100	96.499	ENSCATG00000013541	LARP1B	100	96.499	Cercocebus_atys
ENSG00000138709	LARP1B	100	86.866	ENSCLAG00000006448	-	100	86.866	Chinchilla_lanigera
ENSG00000138709	LARP1B	100	97.162	ENSCSAG00000003582	LARP1B	100	97.162	Chlorocebus_sabaeus
ENSG00000138709	LARP1B	96	100.000	ENSCHOG00000005354	LARP1B	99	81.114	Choloepus_hoffmanni
ENSG00000138709	LARP1B	96	83.333	ENSCPBG00000017480	LARP1B	93	73.447	Chrysemys_picta_bellii
ENSG00000138709	LARP1B	96	100.000	ENSCANG00000026958	LARP1B	99	97.629	Colobus_angolensis_palliatus
ENSG00000138709	LARP1B	100	89.552	ENSCGRG00001004660	-	100	89.552	Cricetulus_griseus_chok1gshd
ENSG00000138709	LARP1B	100	89.254	ENSCGRG00000001914	-	100	89.254	Cricetulus_griseus_crigri
ENSG00000138709	LARP1B	96	54.575	ENSCSEG00000013519	larp1b	90	52.637	Cynoglossus_semilaevis
ENSG00000138709	LARP1B	97	55.484	ENSCVAG00000005046	larp1b	91	53.095	Cyprinodon_variegatus
ENSG00000138709	LARP1B	97	53.564	ENSDARG00000061169	larp1b	85	52.324	Danio_rerio
ENSG00000138709	LARP1B	100	88.462	ENSDNOG00000018765	-	100	87.867	Dasypus_novemcinctus
ENSG00000138709	LARP1B	96	83.333	ENSETEG00000012497	LARP1B	89	83.193	Echinops_telfairi
ENSG00000138709	LARP1B	94	51.676	ENSEBUG00000003668	larp1b	90	51.789	Eptatretus_burgeri
ENSG00000138709	LARP1B	100	96.000	ENSEASG00005018106	LARP1B	98	94.681	Equus_asinus_asinus
ENSG00000138709	LARP1B	96	100.000	ENSECAG00000001088	LARP1B	99	86.494	Equus_caballus
ENSG00000138709	LARP1B	100	45.617	ENSELUG00000023774	larp1b	87	43.896	Esox_lucius
ENSG00000138709	LARP1B	100	91.642	ENSFCAG00000014650	-	100	91.642	Felis_catus
ENSG00000138709	LARP1B	100	68.152	ENSFALG00000008098	LARP1B	99	69.348	Ficedula_albicollis
ENSG00000138709	LARP1B	97	55.901	ENSFHEG00000010264	larp1b	84	55.106	Fundulus_heteroclitus
ENSG00000138709	LARP1B	75	66.667	ENSGMOG00000005207	larp1b	80	67.347	Gadus_morhua
ENSG00000138709	LARP1B	98	69.909	ENSGALG00000010207	LARP1B	92	67.562	Gallus_gallus
ENSG00000138709	LARP1B	91	58.053	ENSGAFG00000012012	larp1b	93	58.324	Gambusia_affinis
ENSG00000138709	LARP1B	97	52.086	ENSGACG00000004609	larp1b	88	52.761	Gasterosteus_aculeatus
ENSG00000138709	LARP1B	96	79.167	ENSGAGG00000017209	LARP1B	93	73.373	Gopherus_agassizii
ENSG00000138709	LARP1B	100	99.421	ENSGGOG00000015900	LARP1B	100	99.421	Gorilla_gorilla
ENSG00000138709	LARP1B	96	56.318	ENSHBUG00000009730	larp1b	87	55.522	Haplochromis_burtoni
ENSG00000138709	LARP1B	97	74.540	ENSHGLG00000013922	-	96	73.700	Heterocephalus_glaber_female
ENSG00000138709	LARP1B	100	85.546	ENSHGLG00000006728	-	98	87.063	Heterocephalus_glaber_female
ENSG00000138709	LARP1B	100	86.269	ENSHGLG00100014041	-	99	86.186	Heterocephalus_glaber_male
ENSG00000138709	LARP1B	97	74.540	ENSHGLG00100016491	-	96	73.700	Heterocephalus_glaber_male
ENSG00000138709	LARP1B	76	59.348	ENSHCOG00000000918	larp1b	96	59.915	Hippocampus_comes
ENSG00000138709	LARP1B	100	51.133	ENSIPUG00000012138	larp1b	85	53.800	Ictalurus_punctatus
ENSG00000138709	LARP1B	100	88.988	ENSSTOG00000008596	-	100	88.988	Ictidomys_tridecemlineatus
ENSG00000138709	LARP1B	91	66.340	ENSSTOG00000033183	-	95	75.403	Ictidomys_tridecemlineatus
ENSG00000138709	LARP1B	96	74.143	ENSSTOG00000034510	-	92	70.000	Ictidomys_tridecemlineatus
ENSG00000138709	LARP1B	99	80.967	ENSSTOG00000021917	-	94	80.967	Ictidomys_tridecemlineatus
ENSG00000138709	LARP1B	99	85.586	ENSJJAG00000022360	Larp1b	99	85.586	Jaculus_jaculus
ENSG00000138709	LARP1B	96	54.057	ENSKMAG00000011589	larp1b	89	53.878	Kryptolebias_marmoratus
ENSG00000138709	LARP1B	97	56.082	ENSLBEG00000005655	larp1b	90	53.982	Labrus_bergylta
ENSG00000138709	LARP1B	99	71.319	ENSLACG00000015247	LARP1B	100	68.448	Latimeria_chalumnae
ENSG00000138709	LARP1B	96	70.833	ENSLOCG00000010684	larp1b	96	64.857	Lepisosteus_oculatus
ENSG00000138709	LARP1B	99	91.667	ENSLAFG00000008473	-	99	92.169	Loxodonta_africana
ENSG00000138709	LARP1B	70	93.793	ENSMFAG00000003306	-	94	93.793	Macaca_fascicularis
ENSG00000138709	LARP1B	100	98.263	ENSMFAG00000002218	LARP1B	100	98.263	Macaca_fascicularis
ENSG00000138709	LARP1B	100	98.209	ENSMMUG00000021347	LARP1B	100	98.209	Macaca_mulatta
ENSG00000138709	LARP1B	96	100.000	ENSMNEG00000030406	LARP1B	100	98.333	Macaca_nemestrina
ENSG00000138709	LARP1B	65	94.406	ENSMNEG00000027747	-	94	94.406	Macaca_nemestrina
ENSG00000138709	LARP1B	96	100.000	ENSMLEG00000009306	LARP1B	100	93.654	Mandrillus_leucophaeus
ENSG00000138709	LARP1B	99	55.861	ENSMAMG00000000081	larp1b	90	55.611	Mastacembelus_armatus
ENSG00000138709	LARP1B	88	53.744	ENSMZEG00005002545	larp1b	94	60.733	Maylandia_zebra
ENSG00000138709	LARP1B	94	62.930	ENSMGAG00000004809	LARP1B	100	62.567	Meleagris_gallopavo
ENSG00000138709	LARP1B	100	88.657	ENSMAUG00000007879	-	100	88.657	Mesocricetus_auratus
ENSG00000138709	LARP1B	100	92.000	ENSMICG00000028052	-	99	70.949	Microcebus_murinus
ENSG00000138709	LARP1B	96	100.000	ENSMICG00000036111	LARP1B	100	93.433	Microcebus_murinus
ENSG00000138709	LARP1B	99	76.389	ENSMICG00000037883	-	98	76.111	Microcebus_murinus
ENSG00000138709	LARP1B	79	90.875	ENSMOCG00000001490	Larp1b	95	90.875	Microtus_ochrogaster
ENSG00000138709	LARP1B	99	85.169	ENSMODG00000012300	LARP1B	94	78.373	Monodelphis_domestica
ENSG00000138709	LARP1B	99	55.626	ENSMALG00000003638	larp1b	89	55.035	Monopterus_albus
ENSG00000138709	LARP1B	100	87.463	MGP_CAROLIEiJ_G0024962	Larp1b	100	87.463	Mus_caroli
ENSG00000138709	LARP1B	100	88.657	ENSMUSG00000025762	Larp1b	100	88.657	Mus_musculus
ENSG00000138709	LARP1B	100	88.358	MGP_PahariEiJ_G0026403	Larp1b	100	88.358	Mus_pahari
ENSG00000138709	LARP1B	100	88.657	MGP_SPRETEiJ_G0025897	Larp1b	100	88.657	Mus_spretus
ENSG00000138709	LARP1B	96	95.833	ENSMPUG00000017365	LARP1B	99	86.750	Mustela_putorius_furo
ENSG00000138709	LARP1B	100	86.301	ENSMLUG00000010229	LARP1B	100	82.391	Myotis_lucifugus
ENSG00000138709	LARP1B	76	56.815	ENSNBRG00000023846	larp1b	84	54.762	Neolamprologus_brichardi
ENSG00000138709	LARP1B	100	98.507	ENSNLEG00000013819	LARP1B	100	98.507	Nomascus_leucogenys
ENSG00000138709	LARP1B	96	83.333	ENSMEUG00000010308	LARP1B	88	81.731	Notamacropus_eugenii
ENSG00000138709	LARP1B	98	73.556	ENSOPRG00000005478	LARP1B	99	71.507	Ochotona_princeps
ENSG00000138709	LARP1B	100	87.164	ENSODEG00000001292	-	100	87.164	Octodon_degus
ENSG00000138709	LARP1B	96	55.496	ENSONIG00000012386	larp1b	99	54.343	Oreochromis_niloticus
ENSG00000138709	LARP1B	98	91.489	ENSOCUG00000013330	LARP1B	98	87.541	Oryctolagus_cuniculus
ENSG00000138709	LARP1B	97	55.844	ENSORLG00000017954	larp1b	87	54.842	Oryzias_latipes
ENSG00000138709	LARP1B	97	55.736	ENSORLG00020013081	larp1b	87	54.425	Oryzias_latipes_hni
ENSG00000138709	LARP1B	97	55.965	ENSORLG00015009580	larp1b	87	54.740	Oryzias_latipes_hsok
ENSG00000138709	LARP1B	97	55.640	ENSOMEG00000004210	larp1b	87	54.286	Oryzias_melastigma
ENSG00000138709	LARP1B	99	89.279	ENSOGAG00000005771	LARP1B	100	89.174	Otolemur_garnettii
ENSG00000138709	LARP1B	96	95.833	ENSOARG00000015300	LARP1B	100	88.865	Ovis_aries
ENSG00000138709	LARP1B	100	99.701	ENSPPAG00000030439	LARP1B	100	99.701	Pan_paniscus
ENSG00000138709	LARP1B	100	92.000	ENSPPRG00000002743	-	100	91.642	Panthera_pardus
ENSG00000138709	LARP1B	100	92.000	ENSPTIG00000011225	LARP1B	100	91.642	Panthera_tigris_altaica
ENSG00000138709	LARP1B	100	99.421	ENSPTRG00000016437	LARP1B	100	99.421	Pan_troglodytes
ENSG00000138709	LARP1B	100	97.921	ENSPANG00000012488	LARP1B	100	97.921	Papio_anubis
ENSG00000138709	LARP1B	96	50.895	ENSPKIG00000014360	larp1b	95	49.475	Paramormyrops_kingsleyae
ENSG00000138709	LARP1B	96	79.167	ENSPSIG00000012885	LARP1B	99	75.000	Pelodiscus_sinensis
ENSG00000138709	LARP1B	79	60.276	ENSPMGG00000007207	larp1b	84	60.138	Periophthalmus_magnuspinnatus
ENSG00000138709	LARP1B	94	52.102	ENSPMAG00000002700	larp1b	97	53.340	Petromyzon_marinus
ENSG00000138709	LARP1B	99	84.222	ENSPCIG00000026516	LARP1B	98	84.780	Phascolarctos_cinereus
ENSG00000138709	LARP1B	97	55.987	ENSPFOG00000019519	larp1b	87	54.554	Poecilia_formosa
ENSG00000138709	LARP1B	98	51.193	ENSPFOG00000022837	-	86	49.172	Poecilia_formosa
ENSG00000138709	LARP1B	97	57.035	ENSPLAG00000007115	larp1b	87	55.499	Poecilia_latipinna
ENSG00000138709	LARP1B	97	56.818	ENSPMEG00000001224	larp1b	86	55.295	Poecilia_mexicana
ENSG00000138709	LARP1B	80	55.594	ENSPREG00000005955	-	93	53.535	Poecilia_reticulata
ENSG00000138709	LARP1B	96	95.833	ENSPCAG00000007546	LARP1B	99	84.699	Procavia_capensis
ENSG00000138709	LARP1B	100	92.537	ENSPCOG00000021874	LARP1B	99	93.793	Propithecus_coquereli
ENSG00000138709	LARP1B	96	91.667	ENSPVAG00000005373	LARP1B	99	82.495	Pteropus_vampyrus
ENSG00000138709	LARP1B	76	62.410	ENSPNYG00000017357	larp1b	94	61.257	Pundamilia_nyererei
ENSG00000138709	LARP1B	96	55.740	ENSPNAG00000008823	larp1b	85	55.603	Pygocentrus_nattereri
ENSG00000138709	LARP1B	100	89.851	ENSRNOG00000038366	Larp1b	100	89.851	Rattus_norvegicus
ENSG00000138709	LARP1B	100	96.332	ENSRBIG00000039982	-	100	96.332	Rhinopithecus_bieti
ENSG00000138709	LARP1B	100	88.358	ENSRBIG00000038568	-	98	83.427	Rhinopithecus_bieti
ENSG00000138709	LARP1B	100	98.263	ENSRROG00000030771	LARP1B	100	98.263	Rhinopithecus_roxellana
ENSG00000138709	LARP1B	100	78.806	ENSRROG00000038525	-	94	89.046	Rhinopithecus_roxellana
ENSG00000138709	LARP1B	98	86.667	ENSSHAG00000014474	LARP1B	100	84.478	Sarcophilus_harrisii
ENSG00000138709	LARP1B	96	55.940	ENSSMAG00000006347	larp1b	94	55.087	Scophthalmus_maximus
ENSG00000138709	LARP1B	96	56.754	ENSSDUG00000004182	larp1b	86	55.499	Seriola_dumerili
ENSG00000138709	LARP1B	99	47.432	ENSSLDG00000014613	larp1b	86	59.508	Seriola_lalandi_dorsalis
ENSG00000138709	LARP1B	100	76.000	ENSSPUG00000011837	LARP1B	97	67.503	Sphenodon_punctatus
ENSG00000138709	LARP1B	97	56.297	ENSSPAG00000017772	larp1b	87	55.186	Stegastes_partitus
ENSG00000138709	LARP1B	100	96.000	ENSSSCG00000034280	LARP1B	99	91.753	Sus_scrofa
ENSG00000138709	LARP1B	73	55.967	ENSSSCG00000040491	-	99	75.862	Sus_scrofa
ENSG00000138709	LARP1B	96	66.129	ENSTGUG00000002098	-	96	66.932	Taeniopygia_guttata
ENSG00000138709	LARP1B	98	52.511	ENSTRUG00000005612	larp1b	87	52.809	Takifugu_rubripes
ENSG00000138709	LARP1B	99	51.884	ENSTNIG00000012398	larp1b	99	53.353	Tetraodon_nigroviridis
ENSG00000138709	LARP1B	96	95.833	ENSTBEG00000004177	LARP1B	88	82.692	Tupaia_belangeri
ENSG00000138709	LARP1B	96	95.833	ENSTTRG00000012984	LARP1B	99	79.803	Tursiops_truncatus
ENSG00000138709	LARP1B	100	81.791	ENSUAMG00000016938	-	100	81.548	Ursus_americanus
ENSG00000138709	LARP1B	96	100.000	ENSUMAG00000007373	LARP1B	98	90.273	Ursus_maritimus
ENSG00000138709	LARP1B	96	100.000	ENSVPAG00000007223	LARP1B	99	77.949	Vicugna_pacos
ENSG00000138709	LARP1B	100	96.000	ENSVVUG00000011307	LARP1B	100	90.588	Vulpes_vulpes
ENSG00000138709	LARP1B	97	60.177	ENSXETG00000022512	larp1b	92	58.793	Xenopus_tropicalis
ENSG00000138709	LARP1B	73	58.963	ENSXCOG00000004435	larp1b	68	59.314	Xiphophorus_couchianus
ENSG00000138709	LARP1B	97	56.742	ENSXMAG00000008150	larp1b	86	55.228	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005634	nucleus	21630459.	HDA	Component