EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000139160 (Gene tree)
Gene ID: 254013
Gene Symbol: ETFBKMT
Alias: DKFZp451L235|MGC50559|C12orf72|METTL20
Full Name: electron transfer flavoprotein subunit beta lysine methyltransferase
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 25,955 bases
Position: chr12:31,647,160-31,673,114
Accession: 28739
RBP type: canonical RBP
Summary: ETFBKMT (Electron Transfer Flavoprotein Subunit Beta Lysine Methyltransferase) is a Protein Coding gene. Among its related pathways are Protein methylation and Metabolism of proteins. An important paralog of this gene is HEMK1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000350353	Met_10	PF02475.16	0.00062	1	1
ENSP00000379112	Met_10	PF02475.16	0.00062	1	1
ENSP00000396123	Met_10	PF02475.16	0.00062	1	1
ENSP00000441421	Met_10	PF02475.16	0.00062	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000539633	ETFBKMT-206	554	-	ENSP00000445165	72 (aa)	-	F5H481
ENST00000538463	ETFBKMT-205	1862	-	ENSP00000441421	262 (aa)	-	Q8IXQ9
ENST00000412352	ETFBKMT-203	1083	-	ENSP00000396123	262 (aa)	-	Q8IXQ9
ENST00000357721	ETFBKMT-201	6128	XM_024448923	ENSP00000350353	262 (aa)	XP_024304691	Q8IXQ9
ENST00000395763	ETFBKMT-202	2055	-	ENSP00000379112	262 (aa)	-	Q8IXQ9
ENST00000538391	ETFBKMT-204	1067	-	ENSP00000437442	114 (aa)	-	G5EA40

Gene Model

Click here to download ENSG00000139160's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000139160	rs183745979	12	31665598	C	Familial squamous cell lung carcinoma	29924316	[2.48-10.33]	5.06	EFO_0000708\|EFO_0006953

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000139160's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000139160	ETFBKMT	100	86.090	ENSAMEG00000009039	ETFBKMT	100	86.090	Ailuropoda_melanoleuca
ENSG00000139160	ETFBKMT	100	91.985	ENSANAG00000028612	ETFBKMT	100	91.985	Aotus_nancymaae
ENSG00000139160	ETFBKMT	100	82.824	ENSBTAG00000000877	ETFBKMT	100	82.824	Bos_taurus
ENSG00000139160	ETFBKMT	100	92.748	ENSCJAG00000042849	ETFBKMT	100	92.748	Callithrix_jacchus
ENSG00000139160	ETFBKMT	100	85.338	ENSCAFG00000010675	ETFBKMT	100	85.338	Canis_familiaris
ENSG00000139160	ETFBKMT	100	85.338	ENSCAFG00020019091	ETFBKMT	100	85.338	Canis_lupus_dingo
ENSG00000139160	ETFBKMT	94	73.171	ENSCAPG00000000171	ETFBKMT	99	73.171	Cavia_aperea
ENSG00000139160	ETFBKMT	94	75.610	ENSCPOG00000003949	ETFBKMT	94	75.610	Cavia_porcellus
ENSG00000139160	ETFBKMT	100	92.748	ENSCCAG00000032994	ETFBKMT	100	92.748	Cebus_capucinus
ENSG00000139160	ETFBKMT	100	97.328	ENSCATG00000043080	ETFBKMT	100	97.328	Cercocebus_atys
ENSG00000139160	ETFBKMT	100	96.947	ENSCSAG00000007414	ETFBKMT	100	96.947	Chlorocebus_sabaeus
ENSG00000139160	ETFBKMT	100	96.947	ENSCANG00000037265	ETFBKMT	100	96.947	Colobus_angolensis_palliatus
ENSG00000139160	ETFBKMT	100	79.008	ENSCGRG00001018178	Etfbkmt	100	79.008	Cricetulus_griseus_chok1gshd
ENSG00000139160	ETFBKMT	100	79.008	ENSCGRG00000001780	Etfbkmt	100	79.008	Cricetulus_griseus_crigri
ENSG00000139160	ETFBKMT	100	84.962	ENSECAG00000005690	ETFBKMT	100	84.962	Equus_caballus
ENSG00000139160	ETFBKMT	100	98.611	ENSGGOG00000003722	ETFBKMT	100	98.473	Gorilla_gorilla
ENSG00000139160	ETFBKMT	100	86.260	ENSSTOG00000026094	ETFBKMT	100	86.260	Ictidomys_tridecemlineatus
ENSG00000139160	ETFBKMT	100	85.714	ENSLAFG00000028045	ETFBKMT	100	85.714	Loxodonta_africana
ENSG00000139160	ETFBKMT	100	97.328	ENSMFAG00000039974	ETFBKMT	100	97.328	Macaca_fascicularis
ENSG00000139160	ETFBKMT	100	97.328	ENSMMUG00000011179	ETFBKMT	100	97.328	Macaca_mulatta
ENSG00000139160	ETFBKMT	100	96.947	ENSMNEG00000005928	ETFBKMT	100	96.947	Macaca_nemestrina
ENSG00000139160	ETFBKMT	100	96.947	ENSMLEG00000044160	ETFBKMT	100	96.947	Mandrillus_leucophaeus
ENSG00000139160	ETFBKMT	100	79.389	ENSMAUG00000005207	Etfbkmt	100	79.389	Mesocricetus_auratus
ENSG00000139160	ETFBKMT	100	77.099	MGP_CAROLIEiJ_G0029076	Etfbkmt	100	80.240	Mus_caroli
ENSG00000139160	ETFBKMT	100	76.718	ENSMUSG00000039958	Etfbkmt	100	79.641	Mus_musculus
ENSG00000139160	ETFBKMT	100	77.099	MGP_PahariEiJ_G0022837	Etfbkmt	100	80.240	Mus_pahari
ENSG00000139160	ETFBKMT	100	77.099	MGP_SPRETEiJ_G0030132	Etfbkmt	100	80.240	Mus_spretus
ENSG00000139160	ETFBKMT	100	85.338	ENSMPUG00000000211	ETFBKMT	100	85.338	Mustela_putorius_furo
ENSG00000139160	ETFBKMT	100	79.008	ENSNGAG00000023022	Etfbkmt	100	79.008	Nannospalax_galili
ENSG00000139160	ETFBKMT	55	63.380	ENSNBRG00000014653	ETFBKMT	62	60.839	Neolamprologus_brichardi
ENSG00000139160	ETFBKMT	100	98.611	ENSNLEG00000016520	ETFBKMT	100	97.710	Nomascus_leucogenys
ENSG00000139160	ETFBKMT	100	87.023	ENSOGAG00000007571	ETFBKMT	100	87.023	Otolemur_garnettii
ENSG00000139160	ETFBKMT	100	100.000	ENSPPAG00000027904	ETFBKMT	100	99.237	Pan_paniscus
ENSG00000139160	ETFBKMT	100	82.707	ENSPTIG00000011790	ETFBKMT	100	82.707	Panthera_tigris_altaica
ENSG00000139160	ETFBKMT	100	100.000	ENSPTRG00000004812	ETFBKMT	100	99.237	Pan_troglodytes
ENSG00000139160	ETFBKMT	100	97.328	ENSPANG00000036031	ETFBKMT	100	97.328	Papio_anubis
ENSG00000139160	ETFBKMT	100	98.092	ENSPPYG00000004399	ETFBKMT	100	98.092	Pongo_abelii
ENSG00000139160	ETFBKMT	100	88.593	ENSPCOG00000008785	ETFBKMT	100	88.593	Propithecus_coquereli
ENSG00000139160	ETFBKMT	100	84.962	ENSPVAG00000014250	ETFBKMT	100	84.962	Pteropus_vampyrus
ENSG00000139160	ETFBKMT	100	78.626	ENSRNOG00000036918	Etfbkmt	100	78.626	Rattus_norvegicus
ENSG00000139160	ETFBKMT	100	96.565	ENSRBIG00000032721	ETFBKMT	100	96.565	Rhinopithecus_bieti
ENSG00000139160	ETFBKMT	100	96.565	ENSRROG00000034511	ETFBKMT	100	96.565	Rhinopithecus_roxellana
ENSG00000139160	ETFBKMT	60	91.720	ENSSBOG00000021796	ETFBKMT	100	91.720	Saimiri_boliviensis_boliviensis
ENSG00000139160	ETFBKMT	60	88.535	ENSTBEG00000012188	ETFBKMT	100	88.535	Tupaia_belangeri
ENSG00000139160	ETFBKMT	100	86.641	ENSTTRG00000004875	ETFBKMT	100	86.641	Tursiops_truncatus
ENSG00000139160	ETFBKMT	100	84.962	ENSUAMG00000005520	ETFBKMT	100	84.962	Ursus_americanus
ENSG00000139160	ETFBKMT	100	84.962	ENSUMAG00000002612	ETFBKMT	100	84.962	Ursus_maritimus
ENSG00000139160	ETFBKMT	60	87.898	ENSVPAG00000004367	ETFBKMT	100	87.898	Vicugna_pacos
ENSG00000139160	ETFBKMT	100	86.090	ENSVVUG00000012506	ETFBKMT	100	86.090	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005737	cytoplasm	23349634.	IDA	Component
GO:0005759	mitochondrial matrix	25416781.	IDA	Component
GO:0005759	mitochondrial matrix	-	TAS	Component
GO:0006479	protein methylation	-	TAS	Process
GO:0016279	protein-lysine N-methyltransferase activity	25023281.25416781.	IMP	Function
GO:0016279	protein-lysine N-methyltransferase activity	-	TAS	Function
GO:0018022	peptidyl-lysine methylation	25416781.	IMP	Process
GO:0018023	peptidyl-lysine trimethylation	25023281.	IMP	Process
GO:0031072	heat shock protein binding	23349634.	IPI	Function
GO:0032991	protein-containing complex	23349634.	IDA	Component
GO:1904733	negative regulation of electron transfer activity	25416781.	IMP	Process
GO:1904736	negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	25416781.	IMP	Process