EuRBPDB

Description

Ensembl ID: ENSG00000139233 (Gene tree)
Gene ID: 84298
Gene Symbol: LLPH
Alias: MGC14817|hLLP|C12orf31
Full Name: LLP homolog, long-term synaptic facilitation factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 14,214 bases
Position: chr12:66,116,555-66,130,768
Accession: 28229
RBP type: non-canonical RBP
Summary: (LLP Homolog, Long-Term Synaptic Facilitation Factor) is a Protein Coding gene.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000446587	LLPH-202	1177	-	ENSP00000437372	129 (aa)	-	Q9BRT6
ENST00000266604	LLPH-201	7746	-	ENSP00000266604	129 (aa)	-	Q9BRT6

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000139233	Creatinine	3.5760000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000139233	rs113866309	12	66123168	C	Pulse pressure	28498854	[1.15-3.28] unit decrease	2.2172	EFO_0005763

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000139233	LLPH	100	78.519	ENSMUSG00000020224	Llph	100	78.519	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001099	basal RNA polymerase II transcription machinery binding	21873635.	IBA	Function
GO:0001099	basal RNA polymerase II transcription machinery binding	-	ISS	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005694	chromosome	20813266.	IDA	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0060999	positive regulation of dendritic spine development	-	ISS	Process
GO:0097484	dendrite extension	21873635.	IBA	Process
GO:0097484	dendrite extension	-	ISS	Process