EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000139579 (Gene tree)
Gene ID: 79035
Gene Symbol: NABP2
Alias: MGC2731|SSB1|hSSB1|SOSS-B1|OBFC2B
Full Name: nucleic acid binding protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 7,840 bases
Position: chr12:56,222,015-56,229,854
Accession: 28412
RBP type: canonical RBP
Summary: Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2B, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM, Jun 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000413902	tRNA_anti-codon	PF01336.25	2.4e-06	1	1
ENSP00000408616	tRNA_anti-codon	PF01336.25	2.7e-06	1	1
ENSP00000267023	tRNA_anti-codon	PF01336.25	5.6e-06	1	1
ENSP00000368862	tRNA_anti-codon	PF01336.25	5.6e-06	1	1
ENSP00000369545	tRNA_anti-codon	PF01336.25	5.6e-06	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
2121740	SSB-1 of the yeast Saccharomyces cerevisiae is a nucleolar-specific, silver-binding protein that is associated with the snR10 and snR11 small nuclear RNAs.	J Cell Biol	1990 Nov	Clark MW	-
2823109	Saccharomyces cerevisiae SSB1 protein and its relationship to nucleolar RNA-binding proteins.	Mol Cell Biol	1987 Aug	Jong AY	-
29150435	Biochemical characterization of INTS3 and C9ORF80, two subunits of hNABP1/2 heterotrimeric complex in nucleic acid binding.	Biochem J	2018 Jan 2	Vidhyasagar V	doi: 10.1042/BCJ20170351.
1482680	Purification of ribonucleoproteins by a novel approach: isolation of the SSB1 ribonucleoprotein from yeast and demonstration that it has no role in mRNA splicing.	Biochim Biophys Acta	1992 Dec 29	Cusick ME	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000341463	NABP2-202	1411	XM_005269147	ENSP00000368862	211 (aa)	XP_005269204	Q9BQ15
ENST00000479016	NABP2-206	1031	-	-	- (aa)	-	-
ENST00000267023	NABP2-201	1417	XM_005269146	ENSP00000267023	211 (aa)	XP_005269203	Q9BQ15
ENST00000380198	NABP2-203	1775	XM_005269149	ENSP00000369545	211 (aa)	XP_005269206	Q9BQ15
ENST00000447747	NABP2-205	770	-	ENSP00000413902	144 (aa)	-	C9JT95
ENST00000399713	NABP2-204	663	-	ENSP00000408616	151 (aa)	-	C9JMP5

Gene Model

Click here to download ENSG00000139579's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000139579's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000139579	NABP2	100	96.209	ENSAMEG00000003630	NABP2	100	96.209	Ailuropoda_melanoleuca
ENSG00000139579	NABP2	98	86.620	ENSACAG00000007650	NABP2	100	76.852	Anolis_carolinensis
ENSG00000139579	NABP2	100	99.306	ENSANAG00000020737	NABP2	100	98.104	Aotus_nancymaae
ENSG00000139579	NABP2	100	94.444	ENSBTAG00000002798	NABP2	100	94.313	Bos_taurus
ENSG00000139579	NABP2	100	99.306	ENSCJAG00000011455	NABP2	100	98.104	Callithrix_jacchus
ENSG00000139579	NABP2	100	95.735	ENSCAFG00000023084	NABP2	100	95.735	Canis_familiaris
ENSG00000139579	NABP2	100	95.735	ENSCAFG00020024920	NABP2	94	95.735	Canis_lupus_dingo
ENSG00000139579	NABP2	100	95.833	ENSTSYG00000029063	NABP2	100	95.261	Carlito_syrichta
ENSG00000139579	NABP2	100	94.444	ENSCPOG00000014895	NABP2	100	93.839	Cavia_porcellus
ENSG00000139579	NABP2	100	99.306	ENSCATG00000031131	NABP2	100	98.578	Cercocebus_atys
ENSG00000139579	NABP2	96	93.103	ENSCLAG00000012948	NABP2	100	93.103	Chinchilla_lanigera
ENSG00000139579	NABP2	100	99.306	ENSCSAG00000005199	NABP2	100	98.578	Chlorocebus_sabaeus
ENSG00000139579	NABP2	100	89.655	ENSCPBG00000013768	NABP2	100	84.579	Chrysemys_picta_bellii
ENSG00000139579	NABP2	100	99.306	ENSCANG00000043770	NABP2	100	98.578	Colobus_angolensis_palliatus
ENSG00000139579	NABP2	100	93.750	ENSCGRG00001022709	Nabp2	93	91.943	Cricetulus_griseus_chok1gshd
ENSG00000139579	NABP2	100	93.750	ENSCGRG00000018023	Nabp2	100	91.943	Cricetulus_griseus_crigri
ENSG00000139579	NABP2	100	89.671	ENSDNOG00000013517	NABP2	93	89.671	Dasypus_novemcinctus
ENSG00000139579	NABP2	100	75.355	ENSDORG00000012936	Nabp2	100	75.355	Dipodomys_ordii
ENSG00000139579	NABP2	86	100.000	ENSETEG00000007056	NABP2	100	100.000	Echinops_telfairi
ENSG00000139579	NABP2	100	95.261	ENSEASG00005004905	NABP2	100	95.261	Equus_asinus_asinus
ENSG00000139579	NABP2	100	95.261	ENSECAG00000008042	NABP2	100	95.261	Equus_caballus
ENSG00000139579	NABP2	100	91.391	ENSEEUG00000001325	-	100	84.834	Erinaceus_europaeus
ENSG00000139579	NABP2	100	95.261	ENSFCAG00000012015	NABP2	100	95.261	Felis_catus
ENSG00000139579	NABP2	65	95.699	ENSFALG00000009257	-	80	95.699	Ficedula_albicollis
ENSG00000139579	NABP2	100	93.377	ENSFDAG00000012266	NABP2	100	93.365	Fukomys_damarensis
ENSG00000139579	NABP2	83	96.667	ENSGALG00000031958	NABP2	100	69.668	Gallus_gallus
ENSG00000139579	NABP2	100	90.345	ENSGAGG00000007253	NABP2	100	84.112	Gopherus_agassizii
ENSG00000139579	NABP2	100	100.000	ENSGGOG00000009050	NABP2	100	100.000	Gorilla_gorilla
ENSG00000139579	NABP2	100	94.040	ENSHGLG00000017829	NABP2	100	93.365	Heterocephalus_glaber_female
ENSG00000139579	NABP2	100	94.040	ENSHGLG00100019193	NABP2	100	93.365	Heterocephalus_glaber_male
ENSG00000139579	NABP2	100	96.209	ENSSTOG00000015937	NABP2	100	96.209	Ictidomys_tridecemlineatus
ENSG00000139579	NABP2	100	95.833	ENSJJAG00000024279	Nabp2	100	95.333	Jaculus_jaculus
ENSG00000139579	NABP2	97	83.688	ENSLACG00000010866	-	100	68.372	Latimeria_chalumnae
ENSG00000139579	NABP2	100	96.528	ENSLAFG00000000193	NABP2	100	95.305	Loxodonta_africana
ENSG00000139579	NABP2	100	99.306	ENSMFAG00000000354	NABP2	100	98.578	Macaca_fascicularis
ENSG00000139579	NABP2	100	99.306	ENSMMUG00000038453	NABP2	100	98.578	Macaca_mulatta
ENSG00000139579	NABP2	100	99.306	ENSMNEG00000027879	NABP2	100	98.578	Macaca_nemestrina
ENSG00000139579	NABP2	100	99.306	ENSMLEG00000042811	NABP2	100	98.578	Mandrillus_leucophaeus
ENSG00000139579	NABP2	100	93.056	ENSMAUG00000002611	Nabp2	100	92.667	Mesocricetus_auratus
ENSG00000139579	NABP2	100	95.833	ENSMICG00000046909	NABP2	100	95.735	Microcebus_murinus
ENSG00000139579	NABP2	100	93.750	ENSMOCG00000020813	Nabp2	100	93.365	Microtus_ochrogaster
ENSG00000139579	NABP2	100	94.079	MGP_CAROLIEiJ_G0015936	Nabp2	100	94.156	Mus_caroli
ENSG00000139579	NABP2	100	94.079	ENSMUSG00000025374	Nabp2	100	94.156	Mus_musculus
ENSG00000139579	NABP2	100	93.103	MGP_PahariEiJ_G0031148	Nabp2	100	92.857	Mus_pahari
ENSG00000139579	NABP2	100	94.079	MGP_SPRETEiJ_G0016761	Nabp2	100	94.156	Mus_spretus
ENSG00000139579	NABP2	100	96.209	ENSMPUG00000001297	-	100	96.209	Mustela_putorius_furo
ENSG00000139579	NABP2	100	95.139	ENSMLUG00000006646	NABP2	100	94.366	Myotis_lucifugus
ENSG00000139579	NABP2	100	96.528	ENSNGAG00000020105	Nabp2	100	95.735	Nannospalax_galili
ENSG00000139579	NABP2	100	90.972	ENSMEUG00000004485	NABP2	100	89.573	Notamacropus_eugenii
ENSG00000139579	NABP2	100	94.444	ENSODEG00000005221	-	93	93.365	Octodon_degus
ENSG00000139579	NABP2	100	95.139	ENSOCUG00000007200	NABP2	100	94.366	Oryctolagus_cuniculus
ENSG00000139579	NABP2	100	93.464	ENSOGAG00000026514	NABP2	100	93.427	Otolemur_garnettii
ENSG00000139579	NABP2	100	95.139	ENSOARG00000009774	NABP2	100	93.506	Ovis_aries
ENSG00000139579	NABP2	100	100.000	ENSPPAG00000000812	NABP2	100	100.000	Pan_paniscus
ENSG00000139579	NABP2	100	95.261	ENSPPRG00000001294	NABP2	100	95.261	Panthera_pardus
ENSG00000139579	NABP2	100	95.261	ENSPTIG00000011222	NABP2	100	95.261	Panthera_tigris_altaica
ENSG00000139579	NABP2	100	100.000	ENSPTRG00000050931	NABP2	100	100.000	Pan_troglodytes
ENSG00000139579	NABP2	100	99.306	ENSPANG00000026357	NABP2	100	98.104	Papio_anubis
ENSG00000139579	NABP2	100	89.655	ENSPSIG00000003187	NABP2	100	83.645	Pelodiscus_sinensis
ENSG00000139579	NABP2	100	94.444	ENSPEMG00000013415	Nabp2	100	93.839	Peromyscus_maniculatus_bairdii
ENSG00000139579	NABP2	100	91.391	ENSPCIG00000024649	-	95	90.521	Phascolarctos_cinereus
ENSG00000139579	NABP2	100	74.882	ENSPCAG00000009311	NABP2	100	74.882	Procavia_capensis
ENSG00000139579	NABP2	100	97.156	ENSPCOG00000014721	NABP2	100	97.156	Propithecus_coquereli
ENSG00000139579	NABP2	100	93.839	ENSPVAG00000007578	NABP2	100	93.839	Pteropus_vampyrus
ENSG00000139579	NABP2	100	94.444	ENSRNOG00000023480	Nabp2	100	92.417	Rattus_norvegicus
ENSG00000139579	NABP2	100	99.306	ENSRBIG00000039231	NABP2	100	98.578	Rhinopithecus_bieti
ENSG00000139579	NABP2	100	99.306	ENSRROG00000044063	NABP2	100	98.578	Rhinopithecus_roxellana
ENSG00000139579	NABP2	100	99.306	ENSSBOG00000010714	NABP2	100	97.156	Saimiri_boliviensis_boliviensis
ENSG00000139579	NABP2	100	88.742	ENSSHAG00000002240	NABP2	100	88.816	Sarcophilus_harrisii
ENSG00000139579	NABP2	100	88.966	ENSSPUG00000002441	NABP2	100	80.374	Sphenodon_punctatus
ENSG00000139579	NABP2	100	96.209	ENSSSCG00000000384	NABP2	100	96.209	Sus_scrofa
ENSG00000139579	NABP2	100	95.139	ENSTTRG00000007083	NABP2	100	93.839	Tursiops_truncatus
ENSG00000139579	NABP2	100	96.209	ENSUAMG00000027231	NABP2	100	96.209	Ursus_americanus
ENSG00000139579	NABP2	100	95.364	ENSUMAG00000016815	NABP2	100	86.321	Ursus_maritimus
ENSG00000139579	NABP2	90	93.122	ENSVVUG00000021962	NABP2	81	93.122	Vulpes_vulpes
ENSG00000139579	NABP2	90	88.372	ENSXETG00000024652	nabp2	99	80.822	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000724	double-strand break repair via homologous recombination	19605351.	IMP	Process
GO:0000784	nuclear chromosome, telomeric region	25589350.	IDA	Component
GO:0003697	single-stranded DNA binding	18449195.19683501.	IDA	Function
GO:0005515	protein binding	18449195.19683501.21242961.21659603.	IPI	Function
GO:0005634	nucleus	18449195.19683501.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006281	DNA repair	18449195.19683501.	IMP	Process
GO:0006281	DNA repair	-	ISS	Process
GO:0006974	cellular response to DNA damage stimulus	18449195.19683501.	IMP	Process
GO:0007093	mitotic cell cycle checkpoint	19683501.	IMP	Process
GO:0010212	response to ionizing radiation	19605351.19683501.	IMP	Process
GO:0042795	snRNA transcription by RNA polymerase II	-	TAS	Process
GO:0051972	regulation of telomerase activity	25589350.	IMP	Process
GO:0061730	C-rich strand telomeric DNA binding	25589350.	IDA	Function
GO:0070182	DNA polymerase binding	25589350.	IPI	Function
GO:0070200	establishment of protein localization to telomere	25589350.	IMP	Process
GO:0070876	SOSS complex	18449195.19683501.	IDA	Component
GO:0098505	G-rich strand telomeric DNA binding	25589350.	IDA	Function
GO:1904355	positive regulation of telomere capping	25589350.	IMP	Process