EuRBPDB

Description

Ensembl ID: ENSG00000139613 (Gene tree)
Gene ID: 6601
Gene Symbol: SMARCC2
Alias: BAF170|Rsc8|CRACC2
Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 27,716 bases
Position: chr12:56,161,852-56,189,567
Accession: 11105
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000267064	SMARCC2-201	4076	XM_005269103	ENSP00000267064	1214 (aa)	XP_005269160	Q8TAQ2
ENST00000552931	SMARCC2-215	608	-	-	- (aa)	-	-
ENST00000394023	SMARCC2-203	4271	XM_005269104	ENSP00000377591	1152 (aa)	XP_005269161	Q8TAQ2
ENST00000550859	SMARCC2-211	656	-	-	- (aa)	-	-
ENST00000549757	SMARCC2-207	1062	-	-	- (aa)	-	-
ENST00000552566	SMARCC2-212	534	-	-	- (aa)	-	-
ENST00000549209	SMARCC2-206	439	-	-	- (aa)	-	-
ENST00000550164	SMARCC2-209	4114	XM_005269102	ENSP00000449396	1245 (aa)	XP_005269159	F8VXC8
ENST00000347471	SMARCC2-202	3839	XM_017019884	ENSP00000302919	1130 (aa)	XP_016875373	Q8TAQ2
ENST00000552674	SMARCC2-214	3730	-	ENSP00000447680	105 (aa)	-	F8VZW6
ENST00000547356	SMARCC2-204	741	-	-	- (aa)	-	-
ENST00000552627	SMARCC2-213	409	-	-	- (aa)	-	-
ENST00000548130	SMARCC2-205	1238	-	-	- (aa)	-	-
ENST00000550519	SMARCC2-210	789	-	ENSP00000449429	105 (aa)	-	F8VZW6
ENST00000550150	SMARCC2-208	3244	-	-	- (aa)	-	-

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa04714	Thermogenesis	KEGG
hsa05225	Hepatocellular carcinoma	KEGG

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000790	nuclear chromatin	16217013.	HDA	Component
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	16217013.	HDA	Function
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	16217013.	HDA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003713	transcription coactivator activity	8804307.	NAS	Function
GO:0005515	protein binding	12192000.12917342.20130577.21044950.28533407.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006337	nucleosome disassembly	8895581.	IDA	Process
GO:0006338	chromatin remodeling	10078207.11018012.11726552.	IDA	Process
GO:0006357	regulation of transcription by RNA polymerase II	8804307.	NAS	Process
GO:0007399	nervous system development	-	IEA	Process
GO:0016514	SWI/SNF complex	8804307.10078207.11078522.	IDA	Component
GO:0031492	nucleosomal DNA binding	16217013.	HDA	Function
GO:0032991	protein-containing complex	16217013.	HDA	Component
GO:0043044	ATP-dependent chromatin remodeling	16217013.	HDA	Process
GO:0045892	negative regulation of transcription, DNA-templated	12192000.	IDA	Process
GO:0045893	positive regulation of transcription, DNA-templated	11018012.	IDA	Process
GO:0071564	npBAF complex	-	ISS	Component
GO:0071565	nBAF complex	-	ISS	Component