EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000140259 (Gene tree)
Gene ID: 4236
Gene Symbol: MFAP1
Alias: AMP
Full Name: microfibril associated protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 20,311 bases
Position: chr15:43,804,492-43,824,802
Accession: 7032
RBP type: non-canonical RBP
Summary: (Microfibril Associated Protein 1) is a Protein Coding gene. Among its related pathways are Elastic fibre formation and Canonical and Non-canonical Notch signaling.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28837687	The spliceosome-associated protein Mfap1 binds to VCP in Drosophila.	PLoS One	2017 Aug 24	Rode S	doi: 10.1371/journal.pone.0183733

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000267812	MFAP1-201	2155	-	ENSP00000267812	439 (aa)	-	P55081
ENST00000484386	MFAP1-202	839	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000140259's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000140259	Platelet Count	4.649e-005	-
ENSG00000140259	Platelet Count	4.649e-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000140259's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000140259	MFAP1	100	99.544	ENSMUSG00000048222	Mfap1b	100	99.544	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	28781166.	IDA	Process
GO:0001527	microfibril	1374398.	IDA	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	22365833.25416956.	IPI	Function
GO:0005576	extracellular region	-	TAS	Component
GO:0005634	nucleus	28781166.	IDA	Component
GO:0071005	U2-type precatalytic spliceosome	28781166.	IDA	Component