EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000140955 (Gene tree)
Gene ID: 161931
Gene Symbol: ADAD2
Alias: TENRL|FLJ00337
Full Name: adenosine deaminase domain containing 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 6,052 bases
Position: chr16:84,191,117-84,197,168
Accession: 30714
RBP type: canonical RBP
Summary: (Adenosine Deaminase Domain Containing 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA binding and adenosine deaminase activity. An important paralog of this gene is ADAD1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000454950	dsrm	PF00035.26	1.1e-07	1	1
ENSP00000325153	dsrm	PF00035.26	3.7e-07	1	1
ENSP00000268624	dsrm	PF00035.26	5.1e-05	1	1
ENSP00000325153	A_deamin	PF02137.18	9.2e-70	1	1
ENSP00000268624	A_deamin	PF02137.18	1.4e-69	1	1
ENSP00000454950	A_deamin	PF02137.18	3e-25	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
26184879	Dynamic profiling of double-stranded RNA binding proteins.	Nucleic Acids Res	2015 Sep 3	Wang X	doi: 10.1093/nar/gkv726

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000567413	ADAD2-207	571	-	-	- (aa)	-	-
ENST00000564169	ADAD2-204	571	-	-	- (aa)	-	-
ENST00000569221	ADAD2-209	553	-	-	- (aa)	-	-
ENST00000315906	ADAD2-202	1995	XM_005255814	ENSP00000325153	583 (aa)	XP_005255871	Q8NCV1
ENST00000567685	ADAD2-208	801	-	ENSP00000454950	267 (aa)	-	H3BNP6
ENST00000566526	ADAD2-206	2542	-	-	- (aa)	-	-
ENST00000563849	ADAD2-203	533	-	-	- (aa)	-	-
ENST00000564430	ADAD2-205	2558	-	-	- (aa)	-	-
ENST00000268624	ADAD2-201	2283	XM_011522919	ENSP00000268624	665 (aa)	XP_011521221	Q8NCV1

Gene Model

Click here to download ENSG00000140955's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000140955	Iron	8.9390000E-004	19880490

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000140955	rs8049634	16	84192073	G	Small cell lung carcinoma	28604730	[1.102930622-1.260860039]	1.1792545	EFO_0000702

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000140955's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000140955	ADAD2	80	32.186	ENSG00000164113	ADAD1	86	32.186
ENSG00000140955	ADAD2	63	30.570	ENSG00000197381	ADARB1	61	30.193
ENSG00000140955	ADAD2	79	30.631	ENSG00000160710	ADAR	51	37.500

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000140955	ADAD2	99	72.727	ENSAMEG00000006263	ADAD2	100	72.727	Ailuropoda_melanoleuca
ENSG00000140955	ADAD2	64	40.420	ENSACAG00000000939	-	99	40.420	Anolis_carolinensis
ENSG00000140955	ADAD2	100	89.880	ENSANAG00000021501	ADAD2	100	90.749	Aotus_nancymaae
ENSG00000140955	ADAD2	98	71.256	ENSBTAG00000034283	ADAD2	99	79.412	Bos_taurus
ENSG00000140955	ADAD2	99	92.105	ENSCJAG00000003981	ADAD2	100	90.088	Callithrix_jacchus
ENSG00000140955	ADAD2	99	73.649	ENSCAFG00000019959	ADAD2	99	79.121	Canis_familiaris
ENSG00000140955	ADAD2	99	72.864	ENSCAFG00020003352	ADAD2	99	79.121	Canis_lupus_dingo
ENSG00000140955	ADAD2	100	73.333	ENSCHIG00000014498	ADAD2	99	79.515	Capra_hircus
ENSG00000140955	ADAD2	99	66.314	ENSTSYG00000032035	ADAD2	99	67.559	Carlito_syrichta
ENSG00000140955	ADAD2	96	66.308	ENSCAPG00000009751	ADAD2	85	69.981	Cavia_aperea
ENSG00000140955	ADAD2	98	64.107	ENSCPOG00000008685	ADAD2	98	70.763	Cavia_porcellus
ENSG00000140955	ADAD2	100	89.365	ENSCCAG00000020693	ADAD2	100	90.088	Cebus_capucinus
ENSG00000140955	ADAD2	100	95.540	ENSCATG00000032653	ADAD2	100	95.540	Cercocebus_atys
ENSG00000140955	ADAD2	99	72.148	ENSCLAG00000001531	ADAD2	99	78.194	Chinchilla_lanigera
ENSG00000140955	ADAD2	100	95.540	ENSCSAG00000003310	ADAD2	100	95.540	Chlorocebus_sabaeus
ENSG00000140955	ADAD2	64	44.236	ENSCPBG00000009418	ADAD2	79	43.011	Chrysemys_picta_bellii
ENSG00000140955	ADAD2	100	94.340	ENSCANG00000039751	ADAD2	100	94.340	Colobus_angolensis_palliatus
ENSG00000140955	ADAD2	98	68.205	ENSCGRG00001022301	Adad2	99	68.205	Cricetulus_griseus_chok1gshd
ENSG00000140955	ADAD2	89	71.654	ENSCGRG00000015879	Adad2	99	75.625	Cricetulus_griseus_crigri
ENSG00000140955	ADAD2	98	71.210	ENSDNOG00000005196	ADAD2	98	71.817	Dasypus_novemcinctus
ENSG00000140955	ADAD2	98	63.452	ENSDORG00000003555	Adad2	99	69.365	Dipodomys_ordii
ENSG00000140955	ADAD2	85	72.751	ENSETEG00000007853	ADAD2	79	73.280	Echinops_telfairi
ENSG00000140955	ADAD2	100	71.453	ENSECAG00000020331	ADAD2	100	79.515	Equus_caballus
ENSG00000140955	ADAD2	100	67.083	ENSEEUG00000007760	ADAD2	100	67.239	Erinaceus_europaeus
ENSG00000140955	ADAD2	99	71.681	ENSFCAG00000030183	ADAD2	100	66.863	Felis_catus
ENSG00000140955	ADAD2	94	66.906	ENSFDAG00000001594	ADAD2	97	72.490	Fukomys_damarensis
ENSG00000140955	ADAD2	66	43.210	ENSGAGG00000018507	ADAD2	84	42.857	Gopherus_agassizii
ENSG00000140955	ADAD2	93	93.939	ENSGGOG00000000944	ADAD2	100	100.000	Gorilla_gorilla
ENSG00000140955	ADAD2	99	67.905	ENSHGLG00000014351	ADAD2	98	76.327	Heterocephalus_glaber_female
ENSG00000140955	ADAD2	94	67.384	ENSHGLG00100002205	ADAD2	91	72.447	Heterocephalus_glaber_male
ENSG00000140955	ADAD2	88	77.600	ENSSTOG00000008305	ADAD2	99	82.105	Ictidomys_tridecemlineatus
ENSG00000140955	ADAD2	88	71.600	ENSJJAG00000019640	Adad2	99	74.790	Jaculus_jaculus
ENSG00000140955	ADAD2	83	41.841	ENSLACG00000006309	-	96	38.200	Latimeria_chalumnae
ENSG00000140955	ADAD2	89	73.518	ENSLAFG00000006071	ADAD2	100	79.289	Loxodonta_africana
ENSG00000140955	ADAD2	100	95.585	ENSMFAG00000044274	ADAD2	100	95.369	Macaca_fascicularis
ENSG00000140955	ADAD2	100	95.364	ENSMMUG00000019188	ADAD2	100	95.197	Macaca_mulatta
ENSG00000140955	ADAD2	100	95.364	ENSMNEG00000036258	ADAD2	100	95.197	Macaca_nemestrina
ENSG00000140955	ADAD2	100	95.369	ENSMLEG00000042324	ADAD2	100	95.369	Mandrillus_leucophaeus
ENSG00000140955	ADAD2	98	67.295	ENSMAUG00000018979	Adad2	99	67.295	Mesocricetus_auratus
ENSG00000140955	ADAD2	99	78.351	ENSMICG00000012378	ADAD2	99	81.182	Microcebus_murinus
ENSG00000140955	ADAD2	98	68.458	ENSMOCG00000002402	Adad2	99	74.617	Microtus_ochrogaster
ENSG00000140955	ADAD2	95	55.926	ENSMODG00000004888	-	98	52.332	Monodelphis_domestica
ENSG00000140955	ADAD2	98	66.954	MGP_CAROLIEiJ_G0031624	Adad2	99	74.833	Mus_caroli
ENSG00000140955	ADAD2	98	68.990	ENSMUSG00000024266	Adad2	99	74.890	Mus_musculus
ENSG00000140955	ADAD2	98	69.164	MGP_PahariEiJ_G0023222	Adad2	99	75.330	Mus_pahari
ENSG00000140955	ADAD2	98	68.870	MGP_SPRETEiJ_G0032742	Adad2	99	75.330	Mus_spretus
ENSG00000140955	ADAD2	99	72.137	ENSMPUG00000008901	ADAD2	99	78.982	Mustela_putorius_furo
ENSG00000140955	ADAD2	99	70.930	ENSMLUG00000003054	ADAD2	99	71.096	Myotis_lucifugus
ENSG00000140955	ADAD2	99	68.793	ENSNGAG00000000370	Adad2	99	76.715	Nannospalax_galili
ENSG00000140955	ADAD2	100	94.714	ENSNLEG00000011048	ADAD2	100	94.714	Nomascus_leucogenys
ENSG00000140955	ADAD2	96	76.327	ENSOPRG00000007920	ADAD2	88	76.770	Ochotona_princeps
ENSG00000140955	ADAD2	99	67.918	ENSODEG00000000488	ADAD2	98	74.779	Octodon_degus
ENSG00000140955	ADAD2	56	59.877	ENSOANG00000007303	-	100	59.574	Ornithorhynchus_anatinus
ENSG00000140955	ADAD2	90	74.510	ENSOCUG00000024782	ADAD2	99	78.958	Oryctolagus_cuniculus
ENSG00000140955	ADAD2	99	74.874	ENSOGAG00000009335	ADAD2	99	74.874	Otolemur_garnettii
ENSG00000140955	ADAD2	54	60.588	ENSOARG00000010532	-	96	59.504	Ovis_aries
ENSG00000140955	ADAD2	100	98.799	ENSPPAG00000028878	ADAD2	100	98.799	Pan_paniscus
ENSG00000140955	ADAD2	100	73.773	ENSPPRG00000000054	ADAD2	100	73.773	Panthera_pardus
ENSG00000140955	ADAD2	100	99.142	ENSPTRG00000008412	ADAD2	100	99.142	Pan_troglodytes
ENSG00000140955	ADAD2	100	95.585	ENSPANG00000010332	ADAD2	100	95.540	Papio_anubis
ENSG00000140955	ADAD2	98	67.130	ENSPEMG00000004734	Adad2	99	67.130	Peromyscus_maniculatus_bairdii
ENSG00000140955	ADAD2	98	56.627	ENSPCIG00000013589	-	99	62.138	Phascolarctos_cinereus
ENSG00000140955	ADAD2	100	97.137	ENSPPYG00000007601	ADAD2	100	95.489	Pongo_abelii
ENSG00000140955	ADAD2	98	74.229	ENSPCAG00000002032	ADAD2	99	67.226	Procavia_capensis
ENSG00000140955	ADAD2	99	71.814	ENSPCOG00000016890	ADAD2	99	72.264	Propithecus_coquereli
ENSG00000140955	ADAD2	98	67.123	ENSRNOG00000015690	Adad2	99	75.056	Rattus_norvegicus
ENSG00000140955	ADAD2	98	89.170	ENSRBIG00000040564	ADAD2	100	85.517	Rhinopithecus_bieti
ENSG00000140955	ADAD2	100	94.511	ENSRROG00000030471	ADAD2	100	94.511	Rhinopithecus_roxellana
ENSG00000140955	ADAD2	100	81.167	ENSSBOG00000017902	ADAD2	100	87.234	Saimiri_boliviensis_boliviensis
ENSG00000140955	ADAD2	98	58.419	ENSSHAG00000012759	ADAD2	98	58.419	Sarcophilus_harrisii
ENSG00000140955	ADAD2	100	73.630	ENSSSCG00000034385	ADAD2	99	80.833	Sus_scrofa
ENSG00000140955	ADAD2	99	66.967	ENSTTRG00000012830	ADAD2	99	66.967	Tursiops_truncatus
ENSG00000140955	ADAD2	98	71.044	ENSUAMG00000005340	ADAD2	99	78.794	Ursus_americanus
ENSG00000140955	ADAD2	99	68.367	ENSUMAG00000015841	ADAD2	99	78.170	Ursus_maritimus
ENSG00000140955	ADAD2	76	81.858	ENSVPAG00000002149	ADAD2	78	76.505	Vicugna_pacos
ENSG00000140955	ADAD2	76	77.419	ENSVVUG00000030274	ADAD2	85	77.419	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003725	double-stranded RNA binding	21873635.	IBA	Function
GO:0003726	double-stranded RNA adenosine deaminase activity	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0006382	adenosine to inosine editing	21873635.	IBA	Process
GO:0006396	RNA processing	21873635.	IBA	Process
GO:0008251	tRNA-specific adenosine deaminase activity	21873635.	IBA	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr16	84191212	5'UTR	novel		0.38
BLCA	chr16	84194443	Frame_Shift_Ins	novel	*C142Pfs23**	0.22
BLCA	chr16	84196673	In_Frame_Del	novel	L518_K520delinsQ	0.34
BRCA	chr16	84194503	Silent	NA	T160T	0.42
BRCA	chr16	84194108	Intron	rs571312243		0.68
BRCA	chr16	84195054	Intron	rs377393194		0.2
CESC	chr16	84195842	Silent	NA	L360L	0.2
CESC	chr16	84195577	Missense_Mutation	novel	G311D	0.14
CESC	chr16	84197044	3'UTR	novel		1
CESC	chr16	84193927	Intron	novel		0.15
CESC	chr16	84195413	Missense_Mutation	novel	H284L	0.13
CESC	chr16	84195414	Missense_Mutation	novel	H284Q	0.12
CESC	chr16	84196349	Missense_Mutation	novel	A502V	0.35
CESC	chr16	84197039	3'UTR	novel		0.26
COAD	chr16	84197002	3'UTR	rs773125900		0.26
COAD	chr16	84195819	Frame_Shift_Del	novel	*T355Pfs22**	0.26
COAD	chr16	84195112	Silent	rs146515699	S217S	0.12
COAD	chr16	84194539	Silent	rs541603528	A172A	0.32
COAD	chr16	84195427	Missense_Mutation	rs779661898	A289T	0.54
COAD	chr16	84196944	Silent	rs776276942	S574S	0.15
COAD	chr16	84196358	Missense_Mutation	NA	R505H	0.38
COAD	chr16	84196650	Silent	rs139489791	A510A	0.41
COAD	chr16	84194966	Frame_Shift_Del	novel	L200*	0.19	dsrm
COAD	chr16	84194107	Intron	rs78344060		0.35
COAD	chr16	84196270	Missense_Mutation	rs754189973	E476K	0.47
COAD	chr16	84195056	Intron	novel		0.07
COAD	chr16	84195590	Silent	novel	S315S	0.14
COAD	chr16	84196670	Missense_Mutation	rs374328634	R517H	0.28
COAD	chr16	84195112	Silent	rs146515699	S217S	0.42
COAD	chr16	84191149	5'Flank	novel		0.34
COAD	chr16	84194426	Intron	novel		0.19
COAD	chr16	84195680	Silent	rs146308441	G345G	0.14
DLBC	chr16	84194460	Missense_Mutation	rs774334290	S146L	0.18
ESCA	chr16	84195174	Missense_Mutation	rs768521238	A238V	0.08	dsrm
ESCA	chr16	84196911	Silent	novel	L563L	0.08
ESCA	chr16	84195055	Intron	novel		0.17
ESCA	chr16	84195093	Missense_Mutation	rs568492054	R211H	0.13	dsrm
GBM	chr16	84191167	5'Flank	rs555632317		0.41
GBM	chr16	84191193	5'UTR	rs771632230		0.41
HNSC	chr16	84195906	Missense_Mutation	novel	V382L	0.13
HNSC	chr16	84195590	Silent	novel	S315S	0.19
KIRC	chr16	84196721	Missense_Mutation	NA	V534A	0.12
KIRC	chr16	84195642	Missense_Mutation	NA	V333F	0.34
KIRC	chr16	84194721	Intron	rs562515455		0.28
KIRC	chr16	84194234	Intron	novel		0.27
KIRC	chr16	84194136	Intron	novel		0.18
KIRP	chr16	84195103	Silent	rs369199969	A214A	0.24
KIRP	chr16	84195338	Missense_Mutation	NA	L259Q	0.37
LIHC	chr16	84196926	Silent	NA	G568G	0.26
LIHC	chr16	84195054	Intron	rs377393194		0.09
LIHC	chr16	84195845	Silent	rs754051500	P361P	0.33
LIHC	chr16	84196721	Missense_Mutation	NA	V534A	1
LIHC	chr16	84195368	Missense_Mutation	rs749009923	C269Y	0.52
LIHC	chr16	84195130	Silent	novel	L223L	0.65
LIHC	chr16	84195570	Missense_Mutation	novel	P309S	0.78
LIHC	chr16	84196361	Missense_Mutation	novel	V506E	0.36
LIHC	chr16	84194035	Intron	novel		0.49
LIHC	chr16	84194280	Intron	novel		0.53
LUAD	chr16	84194125	Intron	novel		0.47
LUAD	chr16	84196027	Missense_Mutation	NA	S422N	0.71
LUAD	chr16	84196739	Missense_Mutation	novel	L540R	0.13
LUAD	chr16	84196251	Silent	NA	G469G	0.15
LUAD	chr16	84195283	Intron	novel		0.33
LUSC	chr16	84195934	In_Frame_Del	novel	G392_L394del	0.2
LUSC	chr16	84195063	Splice_Region	novel		0.44
LUSC	chr16	84191190	5'UTR	novel		0.32
LUSC	chr16	84191375	Frame_Shift_Del	novel	*A50Rfs15**	0.29
LUSC	chr16	84194079	Intron	novel		0.16
LUSC	chr16	84196716	Silent	novel	R532R	0.28
LUSC	chr16	84191363	Missense_Mutation	NA	P45T	0.6
LUSC	chr16	84195444	Splice_Region	novel	L294L	0.3
LUSC	chr16	84195303	Silent	rs374108586	P247P	0.36
OV	chr16	84191255	In_Frame_Ins	novel	D9delinsGSSYAPASSLSH	0.9
OV	chr16	84194956	Missense_Mutation	rs767727592	P195S	0.94	dsrm
OV	chr16	84195633	Missense_Mutation	novel	K330Q	0.17
OV	chr16	84195542	Silent	novel	R299R	0.14
PAAD	chr16	84195906	Missense_Mutation	rs142081193	V382M	0.08
PAAD	chr16	84194539	Silent	rs541603528	A172A	0.55
PAAD	chr16	84191181	5'UTR	novel		0.06
PAAD	chr16	84194505	Missense_Mutation	rs577228328	A161V	0.07
PRAD	chr16	84196231	Missense_Mutation	NA	A463T	0.15
PRAD	chr16	84196694	Missense_Mutation	rs142962765	R525Q	0.44
PRAD	chr16	84195615	Missense_Mutation	rs201035894	G324R	0.1
PRAD	chr16	84196231	Missense_Mutation	NA	A463T	0.37
READ	chr16	84195116	Missense_Mutation	rs200062226	G219S	0.2	dsrm
READ	chr16	84196916	Missense_Mutation	NA	D565G	0.3
READ	chr16	84194197	Intron	rs749673827		0.38
SARC	chr16	84196743	Silent	novel	A541A	0.76
SARC	chr16	84196670	Missense_Mutation	rs374328634	R517H	0.56
SKCM	chr16	84191182	5'UTR	rs756343617		0.42
SKCM	chr16	84191202	5'UTR	novel		0.36
SKCM	chr16	84196224	Silent	NA	V460V	0.29
SKCM	chr16	84196133	Missense_Mutation	rs753412548	S430L	0.34
SKCM	chr16	84191373	Missense_Mutation	rs769891679	A48V	0.33
SKCM	chr16	84195056	Intron	novel		0.52
SKCM	chr16	84191193	5'UTR	rs771632230		0.24
SKCM	chr16	84196336	Missense_Mutation	NA	V498I	0.11
SKCM	chr16	84195594	Silent	rs377399416	L317L	0.51
SKCM	chr16	84195829	Missense_Mutation	rs531531110	S356L	0.63
SKCM	chr16	84196657	Missense_Mutation	NA	G513R	0.45
SKCM	chr16	84191316	Missense_Mutation	rs759599115	P29L	0.47
SKCM	chr16	84194453	Missense_Mutation	NA	P144S	0.29
SKCM	chr16	84196295	Missense_Mutation	rs775453617	G484D	0.92
SKCM	chr16	84196944	Silent	rs776276942	S574S	0.52
SKCM	chr16	84196914	Silent	NA	L564L	0.29
SKCM	chr16	84191359	Nonsense_Mutation	novel	W43*	0.41
SKCM	chr16	84191356	Silent	NA	A42A	0.44
SKCM	chr16	84193956	Intron	novel		0.38
SKCM	chr16	84195295	Splice_Site	NA	X245_splice	0.64
SKCM	chr16	84191220	5'UTR	rs768049958		0.16
SKCM	chr16	84194041	Intron	NA		0.4
SKCM	chr16	84191220	5'UTR	rs768049958		0.43
SKCM	chr16	84195429	Silent	NA	A289A	0.5
SKCM	chr16	84191288	Missense_Mutation	NA	A20T	0.48
SKCM	chr16	84195970	Nonsense_Mutation	novel	W403*	0.35
SKCM	chr16	84194096	Intron	NA		0.38
SKCM	chr16	84196737	Silent	NA	L539L	0.35
SKCM	chr16	84195165	Missense_Mutation	rs769973396	G235E	0.48	dsrm
SKCM	chr16	84196040	Silent	NA	I426I	0.56
SKCM	chr16	84195266	Intron	novel		0.2
SKCM	chr16	84196664	Missense_Mutation	novel	P515L	0.4
STAD	chr16	84191328	Missense_Mutation	rs531866972	R33Q	0.27
STAD	chr16	84196270	Missense_Mutation	rs754189973	E476K	0.2
STAD	chr16	84194007	Intron	novel		0.11
STAD	chr16	84195845	Silent	rs754051500	P361P	0.47
STAD	chr16	84191331	Missense_Mutation	rs377587969	P34L	0.36
STAD	chr16	84196163	Missense_Mutation	novel	A440V	0.29
STAD	chr16	84191208	5'UTR	novel		0.39
STAD	chr16	84195844	Missense_Mutation	rs766729531	P361L	0.63
STAD	chr16	84195598	Missense_Mutation	novel	A318V	0.41
STAD	chr16	84195354	Silent	rs372344589	T264T	0.47
STAD	chr16	84195145	Silent	rs73252701	S228S	0.48
STAD	chr16	84191335	Silent	NA	L35L	0.25
STAD	chr16	84196222	Missense_Mutation	rs369743783	V460I	0.2
STAD	chr16	84191191	5'UTR	rs748035688		0.33
TGCT	chr16	84194206	Intron	novel		0.16
UCEC	chr16	84194400	Intron	novel		0.31
UCEC	chr16	84195406	Missense_Mutation	rs756983411	D282N	0.21
UCEC	chr16	84194502	Missense_Mutation	NA	T160I	0.34
UCEC	chr16	84193993	Intron	novel		0.53
UCEC	chr16	84195057	Intron	NA		0.55
UCEC	chr16	84196944	Silent	rs776276942	S574S	0.52
UCEC	chr16	84195670	Frame_Shift_Del	novel	*K344Rfs33**	0.27
UCEC	chr16	84196257	Silent	novel	P471P	0.2
UCEC	chr16	84194538	Missense_Mutation	rs756625312	A172V	0.23	dsrm
UCEC	chr16	84196257	Silent	novel	P471P	0.15
UCEC	chr16	84194629	Intron	novel		0.12
UCEC	chr16	84194401	Intron	rs767536050		0.41
UCEC	chr16	84194547	Missense_Mutation	novel	A175V	0.11	dsrm
UCEC	chr16	84195136	Silent	rs148697513	D225D	0.33
UCEC	chr16	84196270	Missense_Mutation	rs754189973	E476K	0.34
UCEC	chr16	84196751	Missense_Mutation	novel	T544I	0.29
UCEC	chr16	84193801	Intron	novel		0.33
UCEC	chr16	84194653	Intron	novel		0.24
UCEC	chr16	84195057	Intron	NA		0.39
UCEC	chr16	84195052	Intron	novel		0.28
UCEC	chr16	84194965	Missense_Mutation	NA	A198P	0.51	dsrm
UCEC	chr16	84196651	Missense_Mutation	rs200997815	A511T	0.35
UCEC	chr16	84195393	Silent	NA	G277G	0.27
UCEC	chr16	84196743	Silent	novel	A541A	0.5
UCEC	chr16	84193904	Intron	novel		0.53
UCEC	chr16	84194259	Intron	novel		0.42
UCEC	chr16	84194109	Intron	novel		0.34
UCEC	chr16	84195640	Missense_Mutation	rs371012828	R332H	0.38
UCEC	chr16	84195529	Splice_Site	novel	X295_splice	0.42
UCEC	chr16	84194108	Intron	rs571312243		0.29
UCEC	chr16	84195331	Missense_Mutation	novel	Y257H	0.42	dsrm
UVM	chr16	84196270	Missense_Mutation	rs754189973	E476K	0.14

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.0889	0.061428
CHOL	DEL	0.1667	0.23475
GBM	DEL	0.1161	0.023089
KIRP	DEL	0.0382	0.0042101
LAML	DEL	0.0314	0.0010312
MESO	DEL	0.2414	0.001069
PRAD	DEL	0.3963	4.2517e-39
SKCM	DEL	0.2997	0.0077444
TGCT	DEL	0.3733	0.00015997
THCA	DEL	0.01	0.026572

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.043	Kaplan-Meier Survival Analysis
MESO	0.0013	Kaplan-Meier Survival Analysis
HNSC	0.012	Kaplan-Meier Survival Analysis
COAD	0.0056	Kaplan-Meier Survival Analysis
PAAD	0.029	Kaplan-Meier Survival Analysis
CESC	0.018	Kaplan-Meier Survival Analysis
KICH	0.033	Kaplan-Meier Survival Analysis
UCEC	0.043	Kaplan-Meier Survival Analysis
LIHC	0.028	Kaplan-Meier Survival Analysis
UVM	0.011	Kaplan-Meier Survival Analysis