EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Expression

Transcripts

Gene Model

Click here to download 's gene model file

Pathways

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000140987	Blood Pressure	2.5080000E-005	-
ENSG00000140987	Platelet Function Tests	2.1151280E-006	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000140987	rs1878931	16	3400907	G	Body mass index (adult)	28430825	[-0.1228-0.1908] unit increase	0.034	EFO_0004340

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000140987's network

Orthologs

Gene Ontology

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr16	3390134	Splice_Site	novel	X210_splice	0.55
BLCA	chr16	3382795	3'UTR	novel		0.12
BLCA	chr16	3382908	Missense_Mutation	novel	Q680E	0.11
BLCA	chr16	3382731	3'UTR	novel		0.08
BLCA	chr16	3384677	Missense_Mutation	novel	S339L	0.36
BRCA	chr16	3384862	Silent	NA	L277L	0.16
BRCA	chr16	3382925	Missense_Mutation	novel	S674C	0.06
BRCA	chr16	3382953	Missense_Mutation	NA	H665Y	0.32
BRCA	chr16	3382988	Missense_Mutation	novel	K653R	0.17
BRCA	chr16	3383091	Missense_Mutation	NA	Q619E	0.24
CESC	chr16	3383401	Silent	NA	L515L	0.24
CESC	chr16	3384879	Missense_Mutation	novel	Q272E	0.64
CESC	chr16	3393738	Missense_Mutation	novel	R148T	0.29
CESC	chr16	3393715	Nonsense_Mutation	NA	Q156*	0.4
CESC	chr16	3384520	Silent	NA	F391F	0.31
CESC	chr16	3383177	Missense_Mutation	rs780953755	S590F	0.27
CESC	chr16	3383480	Missense_Mutation	novel	A489V	0.32
CESC	chr16	3383373	Missense_Mutation	novel	E525Q	0.39
CESC	chr16	3383649	Missense_Mutation	novel	E433K	0.13
CESC	chr16	3384624	Nonsense_Mutation	novel	E357*	0.19	zf-C2H2
CESC	chr16	3383692	Missense_Mutation	NA	E418D	0.36
CESC	chr16	3397208	Missense_Mutation	novel	R117K	0.1
COAD	chr16	3390089	Missense_Mutation	NA	Q224H	0.23
COAD	chr16	3400972	5'UTR	novel		0.52
COAD	chr16	3393701	Silent	novel	P160P	0.38
COAD	chr16	3382863	Missense_Mutation	novel	D695Y	0.18
COAD	chr16	3383642	Missense_Mutation	NA	N435S	0.21
COAD	chr16	3397717	5'UTR	novel		0.39
COAD	chr16	3383524	Missense_Mutation	novel	E474D	0.11
COAD	chr16	3382697	3'UTR	rs537919319		0.59
COAD	chr16	3382859	Missense_Mutation	rs542853125	A696V	0.2
COAD	chr16	3397448	Missense_Mutation	novel	R37H	0.42
COAD	chr16	3383126	Missense_Mutation	rs111430390	C607Y	0.35
COAD	chr16	3383789	Intron	novel		0.12
COAD	chr16	3382859	Missense_Mutation	rs542853125	A696V	0.3
COAD	chr16	3384605	Missense_Mutation	novel	A363V	0.3
COAD	chr16	3397246	Silent	rs770824607	N104N	0.37
COAD	chr16	3384753	Nonsense_Mutation	novel	Q314*	0.1
COAD	chr16	3383571	Missense_Mutation	novel	P459S	0.25
COAD	chr16	3382997	Missense_Mutation	NA	A650V	0.16
COAD	chr16	3384774	Missense_Mutation	rs200152894	R307C	0.28
COAD	chr16	3383774	Intron	novel		0.2
COAD	chr16	3397496	Missense_Mutation	rs760946411	G21D	0.41
COAD	chr16	3384512	Missense_Mutation	novel	P394H	0.31
COAD	chr16	3384406	Intron	novel		0.13
DLBC	chr16	3383530	Silent	novel	S472S	0.19
DLBC	chr16	3384848	Missense_Mutation	novel	Q282R	0.25
GBM	chr16	3384791	Missense_Mutation	rs368707453	R301Q	0.29
GBM	chr16	3383159	Missense_Mutation	novel	Q596L	0.05
GBM	chr16	3384258	Intron	novel		0.69
GBM	chr16	3384413	Intron	novel		0.06
HNSC	chr16	3390148	Intron	novel		0.29
HNSC	chr16	3383182	Missense_Mutation	novel	Q588H	0.23
HNSC	chr16	3384561	Missense_Mutation	novel	D378N	0.12
LAML	chr16	3384584	Missense_Mutation	novel	N370S	0.04
LGG	chr16	3383778	Intron	novel		0.18
LGG	chr16	3384792	Missense_Mutation	rs566315752	R301W	0.34
LIHC	chr16	3383548	Missense_Mutation	NA	R466S	0.4
LUAD	chr16	3383208	Missense_Mutation	novel	G580R	0.45
LUAD	chr16	3384572	Missense_Mutation	novel	T374K	0.19
LUAD	chr16	3384811	Silent	NA	L294L	0.3
LUAD	chr16	3384417	Intron	novel		0.09
LUSC	chr16	3384804	Nonsense_Mutation	novel	Q297*	0.17
LUSC	chr16	3384805	Missense_Mutation	novel	E296D	0.17
LUSC	chr16	3390125	Silent	novel	A212A	0.37
LUSC	chr16	3384510	Missense_Mutation	novel	G395S	0.17
LUSC	chr16	3384809	Missense_Mutation	NA	W295S	0.48
LUSC	chr16	3384703	Missense_Mutation	NA	I330M	0.32
LUSC	chr16	3383224	Missense_Mutation	NA	E574D	0.13
OV	chr16	3383207	Missense_Mutation	NA	G580E	0.26
OV	chr16	3384733	Silent	novel	V320V	0.05
OV	chr16	3390161	Intron	rs373598484		0.48
OV	chr16	3382856	Nonsense_Mutation	novel	L697*	0.12
OV	chr16	3384788	Missense_Mutation	NA	T302I	0.4
OV	chr16	3383531	Frame_Shift_Ins	novel	*S472Mfs2**	0.06
OV	chr16	3384261	Intron	novel		0.15
OV	chr16	3390120	Missense_Mutation	rs756325936	R214H	0.15
PAAD	chr16	3382681	3'UTR	novel		0.16
READ	chr16	3382780	3'UTR	novel		0.42
SARC	chr16	3384294	Intron	novel		0.38
SKCM	chr16	3383091	Missense_Mutation	NA	Q619K	0.21
SKCM	chr16	3384770	Missense_Mutation	novel	T308N	0.36
SKCM	chr16	3382961	Missense_Mutation	rs745517954	R662K	0.34
SKCM	chr16	3382960	Missense_Mutation	rs372402522	R662S	0.23
SKCM	chr16	3384409	Intron	novel		0.28
SKCM	chr16	3383301	Missense_Mutation	NA	H549Y	0.15
STAD	chr16	3384756	Missense_Mutation	NA	L313I	0.34
STAD	chr16	3383333	Missense_Mutation	rs375567911	R538Q	0.39
STAD	chr16	3384740	Missense_Mutation	rs199811024	R318H	0.07
STAD	chr16	3383514	Frame_Shift_Ins	novel	*S478Ifs48**	0.41
STAD	chr16	3384841	Silent	NA	S284S	0.13
STAD	chr16	3383705	Missense_Mutation	novel	E414G	0.38
STAD	chr16	3390105	Missense_Mutation	novel	V219A	0.12
UCEC	chr16	3383363	Missense_Mutation	NA	K528T	0.35
UCEC	chr16	3384405	Intron	novel		0.18
UCEC	chr16	3382697	3'UTR	rs537919319		0.41
UCEC	chr16	3390468	Silent	novel	L194L	0.27
UCEC	chr16	3397701	5'UTR	novel		0.18
UCEC	chr16	3384783	Nonsense_Mutation	novel	E304*	0.05
UCEC	chr16	3383642	Missense_Mutation	NA	N435S	0.25
UCEC	chr16	3384774	Missense_Mutation	rs200152894	R307C	0.3
UCEC	chr16	3384278	Intron	novel		0.33
UCEC	chr16	3384578	Frame_Shift_Ins	rs759070342	*E372Gfs17**	0.43
UCEC	chr16	3384673	Silent	NA	G340G	0.14
UCEC	chr16	3384571	Silent	rs770827118	T374T	0.28
UCEC	chr16	3383683	Frame_Shift_Del	novel	*E422Kfs3**	0.32
UCEC	chr16	3382859	Missense_Mutation	rs542853125	A696V	0.13
UCEC	chr16	3393757	Missense_Mutation	novel	A142T	0.53
UCEC	chr16	3383265	Missense_Mutation	rs375098698	R561C	0.42
UCEC	chr16	3393778	Missense_Mutation	novel	K135E	0.49
UCEC	chr16	3383309	Missense_Mutation	novel	E546V	0.06
UCEC	chr16	3384310	Intron	novel		0.12
UCEC	chr16	3383438	Missense_Mutation	novel	C503Y	0.34
UCEC	chr16	3384428	Intron	novel		0.27
UCEC	chr16	3383132	Missense_Mutation	novel	Y605C	0.23
UCEC	chr16	3384643	Silent	rs537182061	S350S	0.13
UCEC	chr16	3384856	Silent	rs767241263	T279T	0.21
UCEC	chr16	3382697	3'UTR	rs537919319		0.43
UCEC	chr16	3384774	Missense_Mutation	rs200152894	R307C	0.36
UCEC	chr16	3393648	Splice_Site	novel	X178_splice	0.38
UCEC	chr16	3383192	Frame_Shift_Ins	novel	*S585Kfs61**	0.07
UCEC	chr16	3384689	Missense_Mutation	novel	M335T	0.09
UCEC	chr16	3382684	3'UTR	novel		0.5
UCEC	chr16	3384786	Missense_Mutation	novel	P303T	0.35
UCEC	chr16	3390064	Nonsense_Mutation	novel	Q233*	0.24
UCEC	chr16	3390080	Missense_Mutation	novel	M227I	0.32
UCEC	chr16	3384628	Silent	novel	G355G	0.42
UCEC	chr16	3383639	Frame_Shift_Del	novel	*K436Rfs47**	0.31
UCEC	chr16	3384407	Intron	novel		0.32
UCEC	chr16	3383324	Missense_Mutation	NA	R541I	0.25
UCEC	chr16	3390117	Missense_Mutation	novel	D215G	0.32
UCEC	chr16	3382722	3'UTR	novel		0.15
UCEC	chr16	3382865	Missense_Mutation	novel	R694I	0.18
UCEC	chr16	3383229	Missense_Mutation	novel	G573W	0.21
UCEC	chr16	3384673	Silent	NA	G340G	0.17
UCEC	chr16	3383057	Missense_Mutation	novel	E630G	0.39
UCEC	chr16	3397238	Missense_Mutation	novel	E107G	0.33
UCEC	chr16	3397473	Missense_Mutation	rs748350796	N29D	0.41
UCEC	chr16	3383537	Missense_Mutation	rs148491043	G470E	0.34

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	AMP	0.5222	0.22898
CHOL	DEL	0.1111	0.23475

Survival Analysis

Cancer	P-value	Q-value
STAD	0.025	Kaplan-Meier Survival Analysis
HNSC	0.008	Kaplan-Meier Survival Analysis
PRAD	0.037	Kaplan-Meier Survival Analysis
LUSC	0.028	Kaplan-Meier Survival Analysis
COAD	0.022	Kaplan-Meier Survival Analysis
READ	0.0072	Kaplan-Meier Survival Analysis
LAML	0.048	Kaplan-Meier Survival Analysis
GBM	0.019	Kaplan-Meier Survival Analysis
THCA	0.046	Kaplan-Meier Survival Analysis
LUAD	0.00023	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742