EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000141994 (Gene tree)
Gene ID: 56931
Gene Symbol: DUS3L
Alias: DUS3|FLJ13896
Full Name: dihydrouridine synthase 3 like
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 6,407 bases
Position: chr19:5,784,832-5,791,238
Accession: 26920
RBP type: canonical RBP
Summary: (Dihydrouridine Synthase 3 Like) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include tRNA dihydrouridine synthase activity. An important paralog of this gene is DUS1L.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000315558	Dus	PF01207.17	2.7e-59	1	1
ENSP00000311977	Dus	PF01207.17	8.4e-59	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000320699	DUS3L-202	1355	-	ENSP00000315558	408 (aa)	-	Q96G46
ENST00000593229	DUS3L-215	249	-	-	- (aa)	-	-
ENST00000589841	DUS3L-205	453	-	-	- (aa)	-	-
ENST00000589854	DUS3L-206	566	-	-	- (aa)	-	-
ENST00000585587	DUS3L-203	895	-	ENSP00000468233	37 (aa)	-	K7ERF2
ENST00000590087	DUS3L-207	379	-	-	- (aa)	-	-
ENST00000592673	DUS3L-214	701	-	-	- (aa)	-	-
ENST00000590343	DUS3L-209	833	-	ENSP00000466351	169 (aa)	-	K7EM42
ENST00000592468	DUS3L-212	797	-	ENSP00000468075	139 (aa)	-	K7ER20
ENST00000589085	DUS3L-204	2301	-	-	- (aa)	-	-
ENST00000590110	DUS3L-208	977	-	ENSP00000465369	217 (aa)	-	K7EJX8
ENST00000592491	DUS3L-213	806	-	ENSP00000467302	77 (aa)	-	K7EPA4
ENST00000590681	DUS3L-210	869	-	-	- (aa)	-	-
ENST00000309061	DUS3L-201	2113	XM_017027020	ENSP00000311977	650 (aa)	XP_016882509	Q96G46
ENST00000591560	DUS3L-211	768	-	ENSP00000467987	171 (aa)	-	K7EQU9

Gene Model

Click here to download ENSG00000141994's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000141994's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000141994	DUS3L	93	74.843	ENSAPOG00000016764	dus3l	97	60.190	Acanthochromis_polyacanthus
ENSG00000141994	DUS3L	93	89.308	ENSAMEG00000012423	-	99	84.074	Ailuropoda_melanoleuca
ENSG00000141994	DUS3L	93	74.214	ENSAOCG00000004343	dus3l	97	60.601	Amphiprion_ocellaris
ENSG00000141994	DUS3L	93	74.214	ENSAPEG00000005828	dus3l	97	60.443	Amphiprion_percula
ENSG00000141994	DUS3L	93	73.585	ENSATEG00000011064	dus3l	100	59.846	Anabas_testudineus
ENSG00000141994	DUS3L	94	79.112	ENSAPLG00000004636	-	100	67.203	Anas_platyrhynchos
ENSG00000141994	DUS3L	88	55.866	ENSACAG00000012955	-	98	45.867	Anolis_carolinensis
ENSG00000141994	DUS3L	100	94.853	ENSANAG00000021997	DUS3L	100	94.853	Aotus_nancymaae
ENSG00000141994	DUS3L	88	76.751	ENSACLG00000011576	dus3l	97	60.952	Astatotilapia_calliptera
ENSG00000141994	DUS3L	98	49.691	ENSAMXG00000043269	dus3l	97	50.391	Astyanax_mexicanus
ENSG00000141994	DUS3L	100	93.714	ENSBTAG00000011842	DUS3L	100	85.474	Bos_taurus
ENSG00000141994	DUS3L	87	57.967	WBGene00021377	Y37E11B.5	88	49.813	Caenorhabditis_elegans
ENSG00000141994	DUS3L	100	94.118	ENSCJAG00000016997	DUS3L	100	94.398	Callithrix_jacchus
ENSG00000141994	DUS3L	99	84.691	ENSCAFG00000018762	DUS3L	100	85.168	Canis_familiaris
ENSG00000141994	DUS3L	99	84.691	ENSCAFG00020018976	-	100	85.168	Canis_lupus_dingo
ENSG00000141994	DUS3L	100	92.437	ENSCHIG00000021327	-	100	85.474	Capra_hircus
ENSG00000141994	DUS3L	94	78.105	ENSCAPG00000012525	DUS3L	100	78.105	Cavia_aperea
ENSG00000141994	DUS3L	100	90.756	ENSCPOG00000021236	DUS3L	100	79.692	Cavia_porcellus
ENSG00000141994	DUS3L	97	94.962	ENSCCAG00000036889	DUS3L	100	94.958	Cebus_capucinus
ENSG00000141994	DUS3L	100	98.529	ENSCATG00000040809	DUS3L	100	98.529	Cercocebus_atys
ENSG00000141994	DUS3L	100	90.756	ENSCLAG00000008470	DUS3L	100	84.000	Chinchilla_lanigera
ENSG00000141994	DUS3L	100	96.919	ENSCSAG00000009883	DUS3L	100	95.566	Chlorocebus_sabaeus
ENSG00000141994	DUS3L	92	82.278	ENSCPBG00000011136	-	98	64.207	Chrysemys_picta_bellii
ENSG00000141994	DUS3L	95	64.815	ENSCING00000004940	zf(c3h)-5	98	53.616	Ciona_intestinalis
ENSG00000141994	DUS3L	88	70.112	ENSCSAVG00000000525	-	100	57.040	Ciona_savignyi
ENSG00000141994	DUS3L	100	98.284	ENSCANG00000036677	DUS3L	100	98.284	Colobus_angolensis_palliatus
ENSG00000141994	DUS3L	93	89.937	ENSCGRG00001023361	Dus3l	96	83.732	Cricetulus_griseus_chok1gshd
ENSG00000141994	DUS3L	93	89.937	ENSCGRG00000005214	Dus3l	96	83.732	Cricetulus_griseus_crigri
ENSG00000141994	DUS3L	93	72.956	ENSCSEG00000014994	dus3l	99	60.097	Cynoglossus_semilaevis
ENSG00000141994	DUS3L	90	72.727	ENSCVAG00000007874	dus3l	97	56.418	Cyprinodon_variegatus
ENSG00000141994	DUS3L	99	73.267	ENSDARG00000099528	dus3l	100	81.250	Danio_rerio
ENSG00000141994	DUS3L	87	86.577	ENSDNOG00000048551	-	95	75.745	Dasypus_novemcinctus
ENSG00000141994	DUS3L	100	92.877	ENSDORG00000006754	Dus3l	95	86.189	Dipodomys_ordii
ENSG00000141994	DUS3L	86	58.523	FBgn0032819	CG10463	100	45.354	Drosophila_melanogaster
ENSG00000141994	DUS3L	100	59.740	ENSETEG00000004749	-	57	93.103	Echinops_telfairi
ENSG00000141994	DUS3L	86	74.571	ENSEBUG00000010532	dus3l	78	60.993	Eptatretus_burgeri
ENSG00000141994	DUS3L	95	74.699	ENSEASG00005023094	-	97	75.212	Equus_asinus_asinus
ENSG00000141994	DUS3L	100	89.916	ENSECAG00000019359	-	100	82.459	Equus_caballus
ENSG00000141994	DUS3L	93	74.843	ENSELUG00000015033	dus3l	98	60.531	Esox_lucius
ENSG00000141994	DUS3L	94	93.766	ENSFCAG00000027534	-	100	92.892	Felis_catus
ENSG00000141994	DUS3L	93	82.390	ENSFALG00000001343	-	99	63.730	Ficedula_albicollis
ENSG00000141994	DUS3L	96	78.470	ENSFDAG00000014182	DUS3L	100	65.443	Fukomys_damarensis
ENSG00000141994	DUS3L	88	77.031	ENSFHEG00000010091	dus3l	100	60.000	Fundulus_heteroclitus
ENSG00000141994	DUS3L	92	73.418	ENSGMOG00000011366	dus3l	98	76.190	Gadus_morhua
ENSG00000141994	DUS3L	99	75.485	ENSGALG00000001800	-	99	63.516	Gallus_gallus
ENSG00000141994	DUS3L	93	72.327	ENSGAFG00000008857	dus3l	97	61.189	Gambusia_affinis
ENSG00000141994	DUS3L	93	72.327	ENSGACG00000004109	dus3l	100	61.120	Gasterosteus_aculeatus
ENSG00000141994	DUS3L	92	82.278	ENSGAGG00000005527	-	99	66.560	Gopherus_agassizii
ENSG00000141994	DUS3L	100	96.610	ENSGGOG00000027433	DUS3L	100	96.610	Gorilla_gorilla
ENSG00000141994	DUS3L	88	76.751	ENSHBUG00000022232	dus3l	97	60.952	Haplochromis_burtoni
ENSG00000141994	DUS3L	100	92.437	ENSHGLG00000013475	DUS3L	100	85.692	Heterocephalus_glaber_female
ENSG00000141994	DUS3L	100	92.717	ENSHGLG00100007077	DUS3L	100	85.846	Heterocephalus_glaber_male
ENSG00000141994	DUS3L	88	78.711	ENSHCOG00000016072	dus3l	97	60.938	Hippocampus_comes
ENSG00000141994	DUS3L	93	74.843	ENSIPUG00000004025	dus3l	97	63.975	Ictalurus_punctatus
ENSG00000141994	DUS3L	100	91.036	ENSSTOG00000025017	DUS3L	97	86.443	Ictidomys_tridecemlineatus
ENSG00000141994	DUS3L	98	91.202	ENSJJAG00000023742	Dus3l	100	81.077	Jaculus_jaculus
ENSG00000141994	DUS3L	93	73.585	ENSKMAG00000009675	dus3l	97	60.539	Kryptolebias_marmoratus
ENSG00000141994	DUS3L	93	73.585	ENSLBEG00000015795	dus3l	95	59.547	Labrus_bergylta
ENSG00000141994	DUS3L	90	81.169	ENSLACG00000001204	dus3l	97	59.883	Latimeria_chalumnae
ENSG00000141994	DUS3L	93	77.500	ENSLOCG00000010531	dus3l	99	59.827	Lepisosteus_oculatus
ENSG00000141994	DUS3L	97	90.476	ENSLAFG00000027552	-	100	81.543	Loxodonta_africana
ENSG00000141994	DUS3L	100	98.529	ENSMFAG00000031910	DUS3L	100	98.529	Macaca_fascicularis
ENSG00000141994	DUS3L	100	98.284	ENSMMUG00000031027	DUS3L	100	98.284	Macaca_mulatta
ENSG00000141994	DUS3L	95	91.781	ENSMNEG00000036509	DUS3L	100	96.476	Macaca_nemestrina
ENSG00000141994	DUS3L	100	98.529	ENSMLEG00000043222	DUS3L	100	98.529	Mandrillus_leucophaeus
ENSG00000141994	DUS3L	93	73.585	ENSMAMG00000015637	dus3l	97	62.599	Mastacembelus_armatus
ENSG00000141994	DUS3L	88	76.751	ENSMZEG00005026661	dus3l	97	60.794	Maylandia_zebra
ENSG00000141994	DUS3L	93	80.503	ENSMGAG00000001547	-	100	67.666	Meleagris_gallopavo
ENSG00000141994	DUS3L	93	89.308	ENSMAUG00000008347	Dus3l	100	83.077	Mesocricetus_auratus
ENSG00000141994	DUS3L	94	92.717	ENSMICG00000007097	DUS3L	100	88.361	Microcebus_murinus
ENSG00000141994	DUS3L	93	89.937	ENSMOCG00000021796	Dus3l	100	83.231	Microtus_ochrogaster
ENSG00000141994	DUS3L	88	77.591	ENSMMOG00000018377	dus3l	97	61.234	Mola_mola
ENSG00000141994	DUS3L	100	82.005	ENSMODG00000001339	-	93	68.460	Monodelphis_domestica
ENSG00000141994	DUS3L	93	73.585	ENSMALG00000007559	dus3l	95	59.486	Monopterus_albus
ENSG00000141994	DUS3L	99	91.317	MGP_CAROLIEiJ_G0021789	Dus3l	97	82.935	Mus_caroli
ENSG00000141994	DUS3L	99	91.317	ENSMUSG00000007603	Dus3l	97	82.775	Mus_musculus
ENSG00000141994	DUS3L	99	91.317	MGP_PahariEiJ_G0020778	Dus3l	99	83.101	Mus_pahari
ENSG00000141994	DUS3L	99	91.317	MGP_SPRETEiJ_G0022700	Dus3l	97	82.775	Mus_spretus
ENSG00000141994	DUS3L	100	91.877	ENSMPUG00000006188	-	100	82.748	Mustela_putorius_furo
ENSG00000141994	DUS3L	95	92.997	ENSMLUG00000007159	-	100	84.098	Myotis_lucifugus
ENSG00000141994	DUS3L	97	92.571	ENSNGAG00000017157	Dus3l	99	80.000	Nannospalax_galili
ENSG00000141994	DUS3L	90	72.727	ENSNBRG00000015011	dus3l	96	55.151	Neolamprologus_brichardi
ENSG00000141994	DUS3L	100	98.284	ENSNLEG00000013734	DUS3L	100	98.284	Nomascus_leucogenys
ENSG00000141994	DUS3L	93	88.679	ENSMEUG00000014401	-	100	79.074	Notamacropus_eugenii
ENSG00000141994	DUS3L	78	87.946	ENSOPRG00000000954	DUS3L	81	87.946	Ochotona_princeps
ENSG00000141994	DUS3L	100	91.597	ENSODEG00000015771	DUS3L	99	83.204	Octodon_degus
ENSG00000141994	DUS3L	88	77.031	ENSONIG00000019793	dus3l	97	60.952	Oreochromis_niloticus
ENSG00000141994	DUS3L	93	87.421	ENSOANG00000004386	-	96	67.963	Ornithorhynchus_anatinus
ENSG00000141994	DUS3L	88	78.711	ENSORLG00000030245	dus3l	95	62.480	Oryzias_latipes
ENSG00000141994	DUS3L	93	75.472	ENSOMEG00000023500	dus3l	96	62.480	Oryzias_melastigma
ENSG00000141994	DUS3L	100	93.838	ENSOGAG00000016549	DUS3L	100	81.595	Otolemur_garnettii
ENSG00000141994	DUS3L	87	93.289	ENSOARG00000007052	-	99	79.223	Ovis_aries
ENSG00000141994	DUS3L	100	99.265	ENSPPAG00000038054	DUS3L	100	99.265	Pan_paniscus
ENSG00000141994	DUS3L	94	92.987	ENSPPRG00000000633	-	100	92.157	Panthera_pardus
ENSG00000141994	DUS3L	100	99.020	ENSPTRG00000010343	DUS3L	100	99.020	Pan_troglodytes
ENSG00000141994	DUS3L	100	91.525	ENSPANG00000015039	DUS3L	100	91.525	Papio_anubis
ENSG00000141994	DUS3L	93	76.730	ENSPKIG00000018035	dus3l	96	63.854	Paramormyrops_kingsleyae
ENSG00000141994	DUS3L	93	82.390	ENSPSIG00000004965	-	98	68.000	Pelodiscus_sinensis
ENSG00000141994	DUS3L	90	77.273	ENSPMGG00000021422	dus3l	93	60.287	Periophthalmus_magnuspinnatus
ENSG00000141994	DUS3L	93	89.308	ENSPEMG00000020784	Dus3l	100	82.308	Peromyscus_maniculatus_bairdii
ENSG00000141994	DUS3L	93	77.987	ENSPMAG00000007671	dus3l	97	62.857	Petromyzon_marinus
ENSG00000141994	DUS3L	93	89.308	ENSPCIG00000008483	-	96	89.881	Phascolarctos_cinereus
ENSG00000141994	DUS3L	88	76.751	ENSPFOG00000006750	dus3l	97	60.876	Poecilia_formosa
ENSG00000141994	DUS3L	88	76.751	ENSPLAG00000011636	dus3l	97	61.453	Poecilia_latipinna
ENSG00000141994	DUS3L	88	76.751	ENSPMEG00000011343	dus3l	94	60.737	Poecilia_mexicana
ENSG00000141994	DUS3L	88	76.471	ENSPREG00000012315	dus3l	97	61.033	Poecilia_reticulata
ENSG00000141994	DUS3L	100	96.610	ENSPPYG00000009435	DUS3L	100	94.343	Pongo_abelii
ENSG00000141994	DUS3L	95	71.795	ENSPCAG00000005233	-	67	71.818	Procavia_capensis
ENSG00000141994	DUS3L	100	93.277	ENSPCOG00000026203	DUS3L	100	89.417	Propithecus_coquereli
ENSG00000141994	DUS3L	84	94.386	ENSPVAG00000010503	-	77	94.386	Pteropus_vampyrus
ENSG00000141994	DUS3L	88	76.751	ENSPNYG00000009052	dus3l	97	61.111	Pundamilia_nyererei
ENSG00000141994	DUS3L	93	76.101	ENSPNAG00000022347	dus3l	97	64.031	Pygocentrus_nattereri
ENSG00000141994	DUS3L	100	83.960	ENSRNOG00000050381	Dus3l	100	81.692	Rattus_norvegicus
ENSG00000141994	DUS3L	91	97.333	ENSRBIG00000025322	DUS3L	100	97.581	Rhinopithecus_bieti
ENSG00000141994	DUS3L	100	98.039	ENSRROG00000037008	DUS3L	100	98.039	Rhinopithecus_roxellana
ENSG00000141994	DUS3L	92	42.857	YLR401C	-	93	36.909	Saccharomyces_cerevisiae
ENSG00000141994	DUS3L	100	94.398	ENSSBOG00000020402	DUS3L	100	94.678	Saimiri_boliviensis_boliviensis
ENSG00000141994	DUS3L	93	87.421	ENSSHAG00000014156	-	97	71.473	Sarcophilus_harrisii
ENSG00000141994	DUS3L	93	77.358	ENSSFOG00015008797	dus3l	99	59.209	Scleropages_formosus
ENSG00000141994	DUS3L	93	71.698	ENSSMAG00000004896	dus3l	98	60.995	Scophthalmus_maximus
ENSG00000141994	DUS3L	93	73.585	ENSSDUG00000013517	dus3l	98	62.539	Seriola_dumerili
ENSG00000141994	DUS3L	93	74.214	ENSSLDG00000016115	dus3l	98	62.166	Seriola_lalandi_dorsalis
ENSG00000141994	DUS3L	99	64.474	ENSSARG00000001454	-	55	82.673	Sorex_araneus
ENSG00000141994	DUS3L	92	81.013	ENSSPUG00000011128	-	100	80.966	Sphenodon_punctatus
ENSG00000141994	DUS3L	93	74.843	ENSSPAG00000018660	dus3l	97	59.609	Stegastes_partitus
ENSG00000141994	DUS3L	94	93.557	ENSSSCG00000040968	-	100	85.845	Sus_scrofa
ENSG00000141994	DUS3L	99	76.471	ENSTGUG00000001021	-	100	69.206	Taeniopygia_guttata
ENSG00000141994	DUS3L	89	84.868	ENSTGUG00000014885	-	100	70.659	Taeniopygia_guttata
ENSG00000141994	DUS3L	88	76.471	ENSTRUG00000013055	dus3l	97	60.443	Takifugu_rubripes
ENSG00000141994	DUS3L	93	72.956	ENSTNIG00000017537	dus3l	99	60.794	Tetraodon_nigroviridis
ENSG00000141994	DUS3L	93	87.421	ENSTTRG00000013600	-	71	92.580	Tursiops_truncatus
ENSG00000141994	DUS3L	94	90.751	ENSUAMG00000024269	-	100	87.085	Ursus_americanus
ENSG00000141994	DUS3L	93	87.578	ENSUMAG00000010831	-	100	78.733	Ursus_maritimus
ENSG00000141994	DUS3L	94	92.717	ENSVVUG00000013781	-	100	84.709	Vulpes_vulpes
ENSG00000141994	DUS3L	100	82.633	ENSXETG00000027405	dus3l	97	67.504	Xenopus_tropicalis
ENSG00000141994	DUS3L	88	76.190	ENSXCOG00000019852	dus3l	92	75.258	Xiphophorus_couchianus
ENSG00000141994	DUS3L	93	71.698	ENSXMAG00000015252	dus3l	98	58.485	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002943	tRNA dihydrouridine synthesis	-	IEA	Process
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0017150	tRNA dihydrouridine synthase activity	21873635.	IBA	Function
GO:0046872	metal ion binding	-	IEA	Function
GO:0050660	flavin adenine dinucleotide binding	-	IEA	Function
GO:0055114	oxidation-reduction process	-	IEA	Process