EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000142207 (Gene tree)
Gene ID: 9875
Gene Symbol: URB1
Alias: KIAA0539|NPA1|C21orf108
Full Name: URB1 ribosome biogenesis homolog
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 82,009 bases
Position: chr21:32,311,018-32,393,026
Accession: 17344
RBP type: canonical RBP
Summary: (URB1 Ribosome Biogenesis Homolog) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000372199	Npa1	PF11707.8	6.8e-86	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000382751	URB1-201	10832	-	ENSP00000372199	2271 (aa)	-	O60287
ENST00000492603	URB1-203	551	-	-	- (aa)	-	-
ENST00000480196	URB1-202	479	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000142207's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000142207's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000142207	URB1	99	42.870	ENSAPOG00000020308	urb1	99	43.285	Acanthochromis_polyacanthus
ENSG00000142207	URB1	100	82.306	ENSAMEG00000011998	URB1	99	82.501	Ailuropoda_melanoleuca
ENSG00000142207	URB1	94	44.677	ENSACIG00000003248	urb1	96	44.677	Amphilophus_citrinellus
ENSG00000142207	URB1	99	40.670	ENSAOCG00000010364	urb1	99	41.057	Amphiprion_ocellaris
ENSG00000142207	URB1	97	53.221	ENSAPEG00000010758	urb1	98	53.221	Amphiprion_percula
ENSG00000142207	URB1	99	43.383	ENSATEG00000011790	urb1	96	44.330	Anabas_testudineus
ENSG00000142207	URB1	97	56.428	ENSAPLG00000012791	URB1	100	56.428	Anas_platyrhynchos
ENSG00000142207	URB1	99	53.704	ENSACAG00000002817	URB1	98	53.656	Anolis_carolinensis
ENSG00000142207	URB1	100	93.486	ENSANAG00000024617	URB1	99	93.548	Aotus_nancymaae
ENSG00000142207	URB1	99	45.033	ENSACLG00000024865	urb1	99	45.011	Astatotilapia_calliptera
ENSG00000142207	URB1	99	40.141	ENSAMXG00000012306	urb1	98	40.374	Astyanax_mexicanus
ENSG00000142207	URB1	99	77.641	ENSBTAG00000012412	URB1	99	77.871	Bos_taurus
ENSG00000142207	URB1	100	92.571	ENSCJAG00000009118	URB1	99	92.586	Callithrix_jacchus
ENSG00000142207	URB1	100	82.405	ENSCAFG00000008892	URB1	99	82.555	Canis_familiaris
ENSG00000142207	URB1	100	82.322	ENSCAFG00020025987	-	99	82.472	Canis_lupus_dingo
ENSG00000142207	URB1	100	81.354	ENSCAFG00020025994	-	99	81.501	Canis_lupus_dingo
ENSG00000142207	URB1	99	77.071	ENSCHIG00000015645	URB1	99	77.299	Capra_hircus
ENSG00000142207	URB1	100	86.570	ENSTSYG00000013286	URB1	99	86.649	Carlito_syrichta
ENSG00000142207	URB1	98	79.622	ENSCAPG00000015589	URB1	99	79.684	Cavia_aperea
ENSG00000142207	URB1	99	80.810	ENSCPOG00000006748	URB1	99	80.919	Cavia_porcellus
ENSG00000142207	URB1	100	93.659	ENSCCAG00000021299	URB1	99	93.722	Cebus_capucinus
ENSG00000142207	URB1	100	95.156	ENSCATG00000042630	URB1	99	95.181	Cercocebus_atys
ENSG00000142207	URB1	100	81.055	ENSCLAG00000005262	URB1	99	81.156	Chinchilla_lanigera
ENSG00000142207	URB1	100	93.512	ENSCSAG00000009584	URB1	99	93.530	Chlorocebus_sabaeus
ENSG00000142207	URB1	99	59.379	ENSCPBG00000006454	URB1	99	59.309	Chrysemys_picta_bellii
ENSG00000142207	URB1	100	95.288	ENSCANG00000031088	URB1	99	95.314	Colobus_angolensis_palliatus
ENSG00000142207	URB1	99	77.441	ENSCGRG00001010616	Urb1	99	77.249	Cricetulus_griseus_chok1gshd
ENSG00000142207	URB1	98	77.003	ENSCGRG00000015840	Urb1	99	77.051	Cricetulus_griseus_crigri
ENSG00000142207	URB1	97	48.663	ENSCSEG00000012616	urb1	99	50.877	Cynoglossus_semilaevis
ENSG00000142207	URB1	96	51.937	ENSCVAG00000009076	urb1	97	53.024	Cyprinodon_variegatus
ENSG00000142207	URB1	99	43.108	ENSDARG00000060308	urb1	99	43.692	Danio_rerio
ENSG00000142207	URB1	85	81.376	ENSDNOG00000015586	URB1	99	81.376	Dasypus_novemcinctus
ENSG00000142207	URB1	100	81.030	ENSDORG00000006735	Urb1	99	81.175	Dipodomys_ordii
ENSG00000142207	URB1	92	80.663	ENSETEG00000009080	URB1	92	80.663	Echinops_telfairi
ENSG00000142207	URB1	100	82.218	ENSEASG00005007711	URB1	99	82.252	Equus_asinus_asinus
ENSG00000142207	URB1	97	88.889	ENSECAG00000013206	URB1	99	88.713	Equus_caballus
ENSG00000142207	URB1	58	86.250	ENSEEUG00000003626	-	57	86.250	Erinaceus_europaeus
ENSG00000142207	URB1	99	44.858	ENSELUG00000020516	urb1	98	44.947	Esox_lucius
ENSG00000142207	URB1	100	82.050	ENSFCAG00000002177	URB1	99	82.369	Felis_catus
ENSG00000142207	URB1	98	51.394	ENSFALG00000004636	URB1	99	51.375	Ficedula_albicollis
ENSG00000142207	URB1	100	81.124	ENSFDAG00000007288	URB1	95	81.261	Fukomys_damarensis
ENSG00000142207	URB1	99	41.225	ENSFHEG00000000202	urb1	98	42.052	Fundulus_heteroclitus
ENSG00000142207	URB1	93	47.350	ENSGMOG00000001838	urb1	93	47.268	Gadus_morhua
ENSG00000142207	URB1	99	56.466	ENSGALG00000015887	URB1	99	56.506	Gallus_gallus
ENSG00000142207	URB1	98	42.552	ENSGAFG00000020694	urb1	96	52.489	Gambusia_affinis
ENSG00000142207	URB1	99	44.221	ENSGACG00000011703	urb1	99	44.327	Gasterosteus_aculeatus
ENSG00000142207	URB1	99	58.566	ENSGAGG00000022544	URB1	99	58.497	Gopherus_agassizii
ENSG00000142207	URB1	100	98.635	ENSGGOG00000000285	URB1	100	98.635	Gorilla_gorilla
ENSG00000142207	URB1	99	45.077	ENSHBUG00000001904	urb1	99	45.055	Haplochromis_burtoni
ENSG00000142207	URB1	99	79.671	ENSHGLG00000004907	URB1	99	79.774	Heterocephalus_glaber_female
ENSG00000142207	URB1	99	80.369	ENSHGLG00100010749	URB1	99	80.476	Heterocephalus_glaber_male
ENSG00000142207	URB1	74	47.750	ENSHCOG00000018683	urb1	97	48.141	Hippocampus_comes
ENSG00000142207	URB1	99	40.939	ENSIPUG00000014721	urb1	99	41.003	Ictalurus_punctatus
ENSG00000142207	URB1	100	83.473	ENSSTOG00000004539	URB1	99	83.672	Ictidomys_tridecemlineatus
ENSG00000142207	URB1	99	45.195	ENSKMAG00000006001	urb1	99	47.443	Kryptolebias_marmoratus
ENSG00000142207	URB1	94	51.109	ENSLBEG00000027208	urb1	98	51.668	Labrus_bergylta
ENSG00000142207	URB1	99	48.312	ENSLACG00000017059	URB1	99	48.312	Latimeria_chalumnae
ENSG00000142207	URB1	99	45.945	ENSLOCG00000009190	urb1	99	46.322	Lepisosteus_oculatus
ENSG00000142207	URB1	99	78.860	ENSLAFG00000010407	URB1	99	78.980	Loxodonta_africana
ENSG00000142207	URB1	100	95.288	ENSMFAG00000034391	URB1	96	95.314	Macaca_fascicularis
ENSG00000142207	URB1	100	95.200	ENSMMUG00000010295	URB1	99	95.225	Macaca_mulatta
ENSG00000142207	URB1	100	93.835	ENSMNEG00000032981	URB1	99	93.855	Macaca_nemestrina
ENSG00000142207	URB1	100	95.597	ENSMLEG00000041435	URB1	99	95.623	Mandrillus_leucophaeus
ENSG00000142207	URB1	99	43.163	ENSMAMG00000011238	urb1	98	43.442	Mastacembelus_armatus
ENSG00000142207	URB1	99	40.526	ENSMZEG00005011862	urb1	99	42.161	Maylandia_zebra
ENSG00000142207	URB1	98	57.143	ENSMGAG00000014512	URB1	99	57.162	Meleagris_gallopavo
ENSG00000142207	URB1	93	80.584	ENSMAUG00000010516	Urb1	99	80.707	Mesocricetus_auratus
ENSG00000142207	URB1	99	86.085	ENSMICG00000016424	URB1	99	86.125	Microcebus_murinus
ENSG00000142207	URB1	99	75.419	ENSMOCG00000012613	Urb1	99	75.463	Microtus_ochrogaster
ENSG00000142207	URB1	99	64.768	ENSMODG00000021076	URB1	99	64.895	Monodelphis_domestica
ENSG00000142207	URB1	94	52.160	ENSMALG00000017411	urb1	97	52.576	Monopterus_albus
ENSG00000142207	URB1	99	75.891	MGP_CAROLIEiJ_G0020948	Urb1	99	76.004	Mus_caroli
ENSG00000142207	URB1	99	76.419	ENSMUSG00000039929	Urb1	99	76.533	Mus_musculus
ENSG00000142207	URB1	99	76.375	MGP_PahariEiJ_G0016653	Urb1	99	76.533	Mus_pahari
ENSG00000142207	URB1	99	76.100	MGP_SPRETEiJ_G0021854	Urb1	99	76.224	Mus_spretus
ENSG00000142207	URB1	100	80.378	ENSMPUG00000001123	URB1	99	80.521	Mustela_putorius_furo
ENSG00000142207	URB1	99	77.905	ENSNGAG00000001905	Urb1	99	77.910	Nannospalax_galili
ENSG00000142207	URB1	82	45.942	ENSNBRG00000001049	urb1	98	46.229	Neolamprologus_brichardi
ENSG00000142207	URB1	100	94.760	ENSNLEG00000026872	URB1	100	94.760	Nomascus_leucogenys
ENSG00000142207	URB1	93	67.176	ENSMEUG00000010828	URB1	95	60.026	Notamacropus_eugenii
ENSG00000142207	URB1	99	74.824	ENSOPRG00000013482	URB1	99	74.967	Ochotona_princeps
ENSG00000142207	URB1	100	79.648	ENSODEG00000002587	URB1	99	79.700	Octodon_degus
ENSG00000142207	URB1	99	45.094	ENSONIG00000005599	urb1	99	45.358	Oreochromis_niloticus
ENSG00000142207	URB1	99	81.085	ENSOCUG00000009381	URB1	99	81.256	Oryctolagus_cuniculus
ENSG00000142207	URB1	99	43.482	ENSORLG00000003429	urb1	99	43.582	Oryzias_latipes
ENSG00000142207	URB1	99	43.294	ENSORLG00020013785	urb1	99	43.392	Oryzias_latipes_hni
ENSG00000142207	URB1	99	42.451	ENSORLG00015019421	urb1	97	46.575	Oryzias_latipes_hsok
ENSG00000142207	URB1	77	50.585	ENSOMEG00000002094	urb1	98	50.585	Oryzias_melastigma
ENSG00000142207	URB1	99	85.374	ENSOGAG00000017140	URB1	99	85.411	Otolemur_garnettii
ENSG00000142207	URB1	97	77.929	ENSOARG00000013679	URB1	99	77.844	Ovis_aries
ENSG00000142207	URB1	100	99.031	ENSPPAG00000003423	URB1	100	99.031	Pan_paniscus
ENSG00000142207	URB1	100	82.130	ENSPPRG00000023131	URB1	99	82.324	Panthera_pardus
ENSG00000142207	URB1	92	80.237	ENSPTIG00000016125	URB1	98	80.237	Panthera_tigris_altaica
ENSG00000142207	URB1	100	98.987	ENSPTRG00000013852	URB1	100	98.987	Pan_troglodytes
ENSG00000142207	URB1	100	95.641	ENSPANG00000021964	URB1	99	95.668	Papio_anubis
ENSG00000142207	URB1	99	45.519	ENSPKIG00000003683	urb1	96	46.181	Paramormyrops_kingsleyae
ENSG00000142207	URB1	99	77.038	ENSPEMG00000021205	Urb1	99	77.130	Peromyscus_maniculatus_bairdii
ENSG00000142207	URB1	73	37.273	ENSPMAG00000009733	URB1	100	34.139	Petromyzon_marinus
ENSG00000142207	URB1	99	64.301	ENSPCIG00000016350	URB1	99	64.536	Phascolarctos_cinereus
ENSG00000142207	URB1	96	42.811	ENSPLAG00000004371	urb1	99	42.811	Poecilia_latipinna
ENSG00000142207	URB1	98	43.525	ENSPMEG00000006634	urb1	98	43.585	Poecilia_mexicana
ENSG00000142207	URB1	98	43.722	ENSPREG00000013453	urb1	98	43.828	Poecilia_reticulata
ENSG00000142207	URB1	100	96.609	ENSPPYG00000011359	URB1	100	96.609	Pongo_abelii
ENSG00000142207	URB1	99	68.051	ENSPCAG00000007430	URB1	99	68.037	Procavia_capensis
ENSG00000142207	URB1	100	87.142	ENSPCOG00000022695	URB1	99	87.179	Propithecus_coquereli
ENSG00000142207	URB1	100	80.678	ENSPVAG00000000889	URB1	99	80.778	Pteropus_vampyrus
ENSG00000142207	URB1	99	43.584	ENSPNYG00000010589	urb1	99	43.556	Pundamilia_nyererei
ENSG00000142207	URB1	99	40.791	ENSPNAG00000019324	urb1	99	40.617	Pygocentrus_nattereri
ENSG00000142207	URB1	99	76.033	ENSRNOG00000002080	Urb1	99	76.235	Rattus_norvegicus
ENSG00000142207	URB1	100	94.672	ENSRBIG00000033122	URB1	99	94.695	Rhinopithecus_bieti
ENSG00000142207	URB1	100	94.716	ENSRROG00000040237	URB1	99	94.739	Rhinopithecus_roxellana
ENSG00000142207	URB1	100	92.694	ENSSBOG00000027672	URB1	99	92.797	Saimiri_boliviensis_boliviensis
ENSG00000142207	URB1	99	63.860	ENSSHAG00000005140	URB1	99	63.979	Sarcophilus_harrisii
ENSG00000142207	URB1	93	46.201	ENSSFOG00015000339	urb1	99	46.035	Scleropages_formosus
ENSG00000142207	URB1	98	44.102	ENSSMAG00000003782	urb1	99	43.928	Scophthalmus_maximus
ENSG00000142207	URB1	99	44.725	ENSSDUG00000012313	urb1	99	44.861	Seriola_dumerili
ENSG00000142207	URB1	99	44.710	ENSSLDG00000023179	urb1	99	44.585	Seriola_lalandi_dorsalis
ENSG00000142207	URB1	99	55.139	ENSSPUG00000012447	URB1	99	55.342	Sphenodon_punctatus
ENSG00000142207	URB1	99	44.222	ENSSPAG00000006325	urb1	99	44.586	Stegastes_partitus
ENSG00000142207	URB1	100	79.429	ENSSSCG00000032024	URB1	99	79.523	Sus_scrofa
ENSG00000142207	URB1	73	58.313	ENSTGUG00000013442	URB1	100	57.980	Taeniopygia_guttata
ENSG00000142207	URB1	99	44.328	ENSTRUG00000009372	urb1	98	44.444	Takifugu_rubripes
ENSG00000142207	URB1	99	43.254	ENSTNIG00000016277	urb1	99	43.359	Tetraodon_nigroviridis
ENSG00000142207	URB1	81	85.217	ENSTBEG00000010044	URB1	81	85.217	Tupaia_belangeri
ENSG00000142207	URB1	91	79.289	ENSTTRG00000007712	URB1	92	79.498	Tursiops_truncatus
ENSG00000142207	URB1	100	81.954	ENSUAMG00000012231	URB1	99	82.103	Ursus_americanus
ENSG00000142207	URB1	95	82.115	ENSUMAG00000017419	URB1	97	83.325	Ursus_maritimus
ENSG00000142207	URB1	68	88.889	ENSVPAG00000001164	URB1	68	88.889	Vicugna_pacos
ENSG00000142207	URB1	100	82.030	ENSVVUG00000000551	URB1	99	82.179	Vulpes_vulpes
ENSG00000142207	URB1	99	50.238	ENSXETG00000009895	urb1	99	50.701	Xenopus_tropicalis
ENSG00000142207	URB1	99	40.731	ENSXCOG00000005500	urb1	98	41.019	Xiphophorus_couchianus
ENSG00000142207	URB1	99	40.803	ENSXMAG00000007253	urb1	98	41.092	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0001650	fibrillar center	-	IDA	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	16963496.	IDA	Component
GO:0005730	nucleolus	12429849.	NAS	Component
GO:0008150	biological_process	-	ND	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr21	32344693	Missense_Mutation	novel	W1378C	0.34
BRCA	chr21	32393307	5'Flank	NA		0.24
BRCA	chr21	32314905	3'UTR	novel		0.19
BRCA	chr21	32316667	Missense_Mutation	rs372120737	V2145M	0.31
BRCA	chr21	32359899	Missense_Mutation	NA	S589C	0.45
BRCA	chr21	32363293	In_Frame_Del	novel	T454_L458delinsI	0.15
BRCA	chr21	32361927	Missense_Mutation	novel	D535V	0.05
BRCA	chr21	32337423	Silent	NA	G1534G	0.33
BRCA	chr21	32347798	Missense_Mutation	novel	V1009G	0.25
BRCA	chr21	32393423	5'Flank	novel		0.17
BRCA	chr21	32337150	Missense_Mutation	NA	K1543N	0.32
BRCA	chr21	32353955	Silent	novel	L798L	0.09
BRCA	chr21	32393263	5'Flank	NA		0.36
BRCA	chr21	32393423	5'Flank	novel		0.17
BRCA	chr21	32338737	Missense_Mutation	rs758188685	G1494R	0.08
BRCA	chr21	32324565	Missense_Mutation	rs763947089	R1720Q	0.27
BRCA	chr21	32384440	Missense_Mutation	NA	E103K	0.13	Npa1
BRCA	chr21	32393204	5'Flank	novel		0.49
BRCA	chr21	32378516	Missense_Mutation	NA	Y198S	0.19	Npa1
BRCA	chr21	32334165	Frame_Shift_Ins	novel	*E1619Rfs17**	0.09
CESC	chr21	32333329	Silent	novel	L1650L	0.11
CESC	chr21	32320612	Missense_Mutation	novel	A1838V	0.12
CESC	chr21	32321852	Silent	NA	F1811F	0.38
CESC	chr21	32322570	Silent	NA	L1750L	0.48
CESC	chr21	32378511	Nonsense_Mutation	NA	Q200*	0.37	Npa1
CESC	chr21	32352905	Splice_Region	rs752139552	A806A	0.48
CESC	chr21	32383523	Missense_Mutation	NA	A156T	0.4	Npa1
CESC	chr21	32337411	Silent	rs547910594	S1538S	0.11
CESC	chr21	32320641	Splice_Site	NA	X1829_splice	0.56
CESC	chr21	32359819	Frame_Shift_Del	novel	*L612Vfs18**	0.19
CESC	chr21	32352881	Silent	NA	T814T	0.17
COAD	chr21	32314935	Missense_Mutation	novel	A2267T	0.45
COAD	chr21	32325371	Missense_Mutation	NA	R1660Q	0.37
COAD	chr21	32366738	Silent	novel	P405P	0.32
COAD	chr21	32314520	3'UTR	NA		0.49
COAD	chr21	32316784	Missense_Mutation	rs763847056	R2106W	0.08
COAD	chr21	32373695	Silent	rs192355871	S276S	0.23
COAD	chr21	32347719	Silent	novel	T1035T	0.41
COAD	chr21	32384328	Missense_Mutation	novel	Y140F	0.34	Npa1
COAD	chr21	32354026	Missense_Mutation	novel	D775N	0.4
COAD	chr21	32314520	3'UTR	NA		0.06
COAD	chr21	32338769	Missense_Mutation	novel	S1483L	0.45
COAD	chr21	32384424	Missense_Mutation	novel	R108Q	0.26	Npa1
COAD	chr21	32349310	Missense_Mutation	novel	N1002K	0.4
COAD	chr21	32384430	Nonsense_Mutation	novel	L106*	0.14	Npa1
COAD	chr21	32347317	Silent	NA	L1169L	0.32
COAD	chr21	32363313	Missense_Mutation	novel	V451A	0.26
COAD	chr21	32384317	Missense_Mutation	NA	Y144H	0.25	Npa1
COAD	chr21	32325322	Silent	novel	S1676S	0.53
COAD	chr21	32347064	Nonsense_Mutation	novel	Q1254*	0.08
COAD	chr21	32344743	Missense_Mutation	NA	D1362N	0.53
COAD	chr21	32347615	Missense_Mutation	novel	G1070V	0.2
COAD	chr21	32321862	Missense_Mutation	novel	R1808H	0.2
COAD	chr21	32321906	Silent	novel	R1793R	0.11
COAD	chr21	32322559	Silent	novel	S1753S	0.69
COAD	chr21	32346967	Missense_Mutation	novel	R1286H	0.2
COAD	chr21	32324517	Missense_Mutation	novel	K1736R	0.16
COAD	chr21	32333408	Silent	NA	E1623E	0.17
COAD	chr21	32337422	Missense_Mutation	novel	A1535T	0.23
COAD	chr21	32345500	Missense_Mutation	NA	S1315N	0.22
COAD	chr21	32352888	Missense_Mutation	novel	Y812C	0.56
COAD	chr21	32317066	Splice_Site	NA	X2012_splice	0.43
COAD	chr21	32333389	Missense_Mutation	NA	S1630C	0.42
COAD	chr21	32350710	Silent	rs769221746	F942F	0.39
COAD	chr21	32345429	Missense_Mutation	novel	S1339C	0.7
COAD	chr21	32347602	Silent	NA	R1074R	0.29
COAD	chr21	32324565	Missense_Mutation	rs763947089	R1720Q	0.28
COAD	chr21	32344653	Missense_Mutation	rs564985567	V1392M	0.18
COAD	chr21	32316514	Nonsense_Mutation	NA	E2196*	0.43
DLBC	chr21	32375420	In_Frame_Del	novel	L244del	0.1	Npa1
DLBC	chr21	32366674	Missense_Mutation	novel	M427V	0.08
ESCA	chr21	32392896	Missense_Mutation	novel	K5N	0.38
ESCA	chr21	32345394	Silent	novel	H1350H	0.18
ESCA	chr21	32393175	5'Flank	novel		0.2
ESCA	chr21	32321937	Missense_Mutation	novel	T1783K	0.4
GBM	chr21	32377188	Intron	novel		0.13
HNSC	chr21	32312081	3'UTR	novel		0.26
KIRC	chr21	32325251	Missense_Mutation	NA	A1700V	0.13
KIRC	chr21	32350776	Silent	novel	S920S	0.14
KIRC	chr21	32350777	Missense_Mutation	novel	S920Y	0.14
KIRC	chr21	32372518	Silent	NA	G330G	0.32
KIRC	chr21	32316650	Silent	NA	F2150F	0.19
KIRP	chr21	32372535	Missense_Mutation	novel	Y325H	0.58	Npa1
KIRP	chr21	32315047	Silent	novel	A2229A	0.47
KIRP	chr21	32317718	Frame_Shift_Del	novel	*E1996Dfs6**	0.15
KIRP	chr21	32355556	Missense_Mutation	NA	D667Y	0.71
LIHC	chr21	32314968	Missense_Mutation	novel	A2256T	0.42
LIHC	chr21	32333364	Missense_Mutation	novel	Y1638C	0.27
LIHC	chr21	32316783	Missense_Mutation	novel	R2106L	0.43
LIHC	chr21	32319273	Silent	NA	A1912A	0.27
LUAD	chr21	32384462	Splice_Region	novel	T95T	1
LUSC	chr21	32311624	3'UTR	novel		0.14
READ	chr21	32325368	Missense_Mutation	NA	K1661T	0.14
READ	chr21	32355559	Missense_Mutation	rs371125131	R666W	0.32
READ	chr21	32314776	3'UTR	novel		0.21
READ	chr21	32314404	3'UTR	novel		0.53
READ	chr21	32372587	Frame_Shift_Del	novel	*V303Afs2**	0.35	Npa1
SARC	chr21	32347401	Silent	rs770282430	T1141T	0.06
SARC	chr21	32334245	Missense_Mutation	novel	D1592G	0.24
SARC	chr21	32368497	Missense_Mutation	rs759025984	P368L	0.33	Npa1
SKCM	chr21	32314657	3'UTR	rs771307206		0.3
SKCM	chr21	32377264	Intron	novel		0.22
SKCM	chr21	32377297	Intron	novel		0.31
SKCM	chr21	32377293	Intron	novel		0.24
STAD	chr21	32311520	3'UTR	novel		0.75
STAD	chr21	32373695	Silent	rs192355871	S276S	0.5
UCEC	chr21	32314506	3'UTR	novel		0.3
UCEC	chr21	32345548	Missense_Mutation	NA	R1299M	0.26
UCEC	chr21	32314506	3'UTR	novel		0.46
UCEC	chr21	32314935	Missense_Mutation	novel	A2267T	0.41
UCEC	chr21	32316669	Missense_Mutation	NA	A2144V	0.22
UCEC	chr21	32316823	Missense_Mutation	rs556682663	V2093I	0.42
UCEC	chr21	32317900	Missense_Mutation	novel	V1937A	0.17
UCEC	chr21	32322544	Silent	novel	S1758S	0.43
UCEC	chr21	32344622	Missense_Mutation	novel	D1402G	0.07
UCEC	chr21	32359906	Missense_Mutation	novel	V587L	0.16
UCEC	chr21	32372517	Missense_Mutation	novel	T331A	0.32	Npa1
UCEC	chr21	32383458	Missense_Mutation	novel	K177N	0.39	Npa1
UCEC	chr21	32317838	Nonsense_Mutation	novel	Q1958*	0.37
UCEC	chr21	32345413	Missense_Mutation	rs374160696	R1344H	0.53
UCEC	chr21	32350845	Silent	novel	A897A	0.46
UCEC	chr21	32324565	Missense_Mutation	rs763947089	R1720Q	0.21
UCEC	chr21	32311646	3'UTR	novel		0.67
UCEC	chr21	32317836	Missense_Mutation	novel	Q1958H	0.33
UCEC	chr21	32337113	Missense_Mutation	novel	L1556F	0.35
UCEC	chr21	32347409	Nonsense_Mutation	novel	Q1139*	0.58
UCEC	chr21	32373762	Missense_Mutation	novel	N254T	0.41	Npa1
UCEC	chr21	32314519	3'UTR	rs775646260		0.67
UCEC	chr21	32314999	Silent	novel	A2245A	0.34
UCEC	chr21	32321878	Missense_Mutation	NA	E1803K	0.34
UCEC	chr21	32325371	Missense_Mutation	NA	R1660Q	0.44
UCEC	chr21	32333397	Missense_Mutation	NA	K1627R	0.42
UCEC	chr21	32383523	Missense_Mutation	NA	A156T	0.42	Npa1
UCEC	chr21	32344613	Frame_Shift_Del	novel	*Q1405Rfs11**	0.37
UCEC	chr21	32337134	Nonsense_Mutation	novel	R1549*	0.27
UCEC	chr21	32316864	Missense_Mutation	novel	P2079H	0.09
UCEC	chr21	32311511	3'UTR	novel		0.56
UCEC	chr21	32312008	3'UTR	rs199770057		0.52
UCEC	chr21	32338854	Missense_Mutation	rs762722774	V1455I	0.32
UCEC	chr21	32337437	Missense_Mutation	novel	L1530I	0.37
UCEC	chr21	32368591	Missense_Mutation	novel	N337H	0.43	Npa1
UCEC	chr21	32385622	Missense_Mutation	novel	E69K	0.27
UCEC	chr21	32325368	Missense_Mutation	NA	K1661T	0.24
UCEC	chr21	32368429	Silent	novel	L391L	0.12
UCEC	chr21	32361016	Missense_Mutation	NA	L583F	0.12
UCEC	chr21	32347028	Missense_Mutation	novel	D1266N	0.4
UCEC	chr21	32385589	Missense_Mutation	novel	E80K	0.42	Npa1
UCEC	chr21	32349472	Silent	NA	S948S	0.38
UCEC	chr21	32363234	Missense_Mutation	NA	E477D	0.08
UCEC	chr21	32344753	Nonsense_Mutation	NA	W1358*	0.24
UCEC	chr21	32368496	Silent	rs750787853	P368P	0.21
UCEC	chr21	32350921	Missense_Mutation	novel	L872P	0.28
UCEC	chr21	32350847	Missense_Mutation	novel	A897S	0.2
UCEC	chr21	32383496	Missense_Mutation	novel	A165T	0.13	Npa1
UCEC	chr21	32385641	Missense_Mutation	NA	E62D	0.41
UCEC	chr21	32378474	Missense_Mutation	novel	S212N	0.11	Npa1
UCEC	chr21	32361929	Silent	rs748524385	S534S	0.1
UCEC	chr21	32357641	Nonsense_Mutation	novel	E629*	0.38
UCEC	chr21	32314913	3'UTR	novel		0.48
UCEC	chr21	32317014	Missense_Mutation	novel	P2029L	0.26
UCEC	chr21	32317796	Missense_Mutation	novel	V1972M	0.21
UCEC	chr21	32322569	Missense_Mutation	novel	L1750P	0.23
UCEC	chr21	32337507	Silent	novel	L1506L	0.26
UCEC	chr21	32344653	Missense_Mutation	rs564985567	V1392M	0.5
UCEC	chr21	32347271	Missense_Mutation	novel	G1185W	0.19
UCEC	chr21	32377209	Intron	novel		0.22
UCEC	chr21	32317793	Missense_Mutation	novel	L1973F	0.22
UCEC	chr21	32322565	Silent	NA	K1751K	0.31
UCEC	chr21	32354070	Missense_Mutation	novel	G760V	0.44
UCEC	chr21	32321896	Missense_Mutation	novel	R1797C	0.39
UCEC	chr21	32384328	Missense_Mutation	novel	Y140C	0.44	Npa1
UCEC	chr21	32393313	5'Flank	rs368033889		0.4
UCEC	chr21	32314962	Missense_Mutation	novel	V2258M	0.22
UCEC	chr21	32314529	3'UTR	novel		0.32
UCEC	chr21	32311612	3'UTR	novel		0.55
UCEC	chr21	32320550	Missense_Mutation	novel	L1859V	0.18
UCEC	chr21	32350908	Missense_Mutation	novel	Q876H	0.27
UCEC	chr21	32352881	Silent	NA	T814T	0.45
UCEC	chr21	32320574	Missense_Mutation	novel	D1851Y	0.51
UCEC	chr21	32334295	Missense_Mutation	novel	K1575N	0.4
UCEC	chr21	32347289	Missense_Mutation	novel	E1179K	0.57
UCEC	chr21	32392826	Nonsense_Mutation	novel	E29*	0.31
UCEC	chr21	32347785	Frame_Shift_Del	novel	*A1012Sfs28**	0.15
UCEC	chr21	32314535	3'UTR	novel		0.24
UCEC	chr21	32314520	3'UTR	NA		0.54
UCEC	chr21	32384462	Splice_Region	NA	T95T	0.33
UCEC	chr21	32350721	Missense_Mutation	NA	V939L	0.36
UCEC	chr21	32325343	Silent	novel	G1669G	0.26
UCEC	chr21	32354973	Missense_Mutation	NA	P711S	0.33
UCEC	chr21	32384329	Missense_Mutation	novel	Y140H	0.33	Npa1
UCEC	chr21	32347147	Missense_Mutation	novel	R1226H	0.35
UCEC	chr21	32334183	Missense_Mutation	novel	R1613W	0.38
UCEC	chr21	32366690	Silent	novel	R421R	0.41
UCEC	chr21	32347479	Missense_Mutation	novel	M1115I	0.36
UCEC	chr21	32377289	Intron	novel		0.21
UCEC	chr21	32321936	Silent	novel	T1783T	0.41
UCEC	chr21	32347289	Missense_Mutation	novel	E1179K	0.38
UCEC	chr21	32350872	Silent	novel	S888S	0.45
UCEC	chr21	32354009	Silent	rs372511273	T780T	0.39
UCEC	chr21	32366635	Missense_Mutation	rs765229685	F440L	0.31
UCEC	chr21	32312008	3'UTR	rs199770057		0.47
UCEC	chr21	32349466	Silent	novel	G950G	0.44
UCEC	chr21	32368599	Splice_Site	novel	X334_splice	0.44
UCEC	chr21	32316544	Missense_Mutation	rs758730332	R2186W	0.36
UCEC	chr21	32322565	Missense_Mutation	NA	K1751N	0.1
UCEC	chr21	32354978	Missense_Mutation	rs190315797	A709V	0.23
UCEC	chr21	32314776	3'UTR	novel		0.47
UCEC	chr21	32354977	Silent	NA	A709A	0.1
UCEC	chr21	32368407	Missense_Mutation	novel	N398T	0.26
UCEC	chr21	32378492	Missense_Mutation	novel	L206S	0.19	Npa1
UCEC	chr21	32385608	Missense_Mutation	novel	K73N	0.33
UCEC	chr21	32341514	Missense_Mutation	novel	N1423S	0.32
UCEC	chr21	32345465	Missense_Mutation	novel	A1327S	0.35
UCEC	chr21	32350896	Silent	rs373405149	S880S	0.24
UCEC	chr21	32368463	Silent	rs375489185	T379T	0.34
UCEC	chr21	32372510	Missense_Mutation	NA	G333D	0.08	Npa1
UCEC	chr21	32350862	Missense_Mutation	novel	A892T	0.33
UCEC	chr21	32393256	5'Flank	novel		0.28
UCEC	chr21	32345468	Missense_Mutation	novel	L1326M	0.11
UCEC	chr21	32359825	Missense_Mutation	novel	A614T	0.29
UCEC	chr21	32316812	Silent	rs766723889	A2096A	0.17
UCEC	chr21	32373773	Splice_Site	novel	X251_splice	0.41
UCEC	chr21	32377209	Intron	novel		0.43
UCEC	chr21	32366739	Missense_Mutation	rs187485893	P405L	0.21
UCEC	chr21	32314511	3'UTR	rs778506666		0.44
UCEC	chr21	32316468	Missense_Mutation	NA	Q2211P	0.67
UCEC	chr21	32316839	Silent	NA	S2087S	0.45
UCEC	chr21	32325356	Nonsense_Mutation	NA	S1665*	0.36
UCEC	chr21	32375427	Missense_Mutation	NA	N241D	0.39	Npa1
UCEC	chr21	32350830	Silent	rs368432855	A902A	0.62
UCEC	chr21	32344750	Silent	rs747425388	I1359I	0.4
UCEC	chr21	32353968	Missense_Mutation	NA	R794M	0.28
UCEC	chr21	32366753	Splice_Region	NA	I400I	0.21
UCEC	chr21	32312177	3'UTR	novel		0.43
UCEC	chr21	32314706	3'UTR	novel		0.19
UCEC	chr21	32341512	Nonsense_Mutation	novel	E1424*	0.46
UCEC	chr21	32375422	Missense_Mutation	novel	I242M	0.42	Npa1
UCEC	chr21	32314360	3'UTR	novel		0.57
UCEC	chr21	32314520	3'UTR	NA		0.37
UCEC	chr21	32338825	Silent	rs146193643	S1464S	0.36
UCEC	chr21	32377220	Intron	rs755282545		0.32
UCEC	chr21	32352818	Silent	novel	Q835Q	0.43
UCEC	chr21	32334183	Missense_Mutation	novel	R1613W	0.4
UCEC	chr21	32347391	Missense_Mutation	rs551799266	G1145R	0.35
UCEC	chr21	32352762	Missense_Mutation	rs764653010	R854Q	0.34
UCEC	chr21	32372529	Missense_Mutation	novel	A327T	0.35	Npa1
UCEC	chr21	32319281	Missense_Mutation	rs764738571	R1910W	0.36
UCEC	chr21	32393525	5'Flank	novel		0.35

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.1593	0.19516
PAAD	DEL	0.1793	0.10872

Survival Analysis

Cancer	P-value	Q-value
MESO	0.009	Kaplan-Meier Survival Analysis
SKCM	0.018	Kaplan-Meier Survival Analysis
ESCA	0.001	Kaplan-Meier Survival Analysis
PAAD	0.045	Kaplan-Meier Survival Analysis
PCPG	0.043	Kaplan-Meier Survival Analysis
CESC	0.011	Kaplan-Meier Survival Analysis
UCEC	0.024	Kaplan-Meier Survival Analysis
LIHC	0.0019	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
UVM	0.0033	Kaplan-Meier Survival Analysis
OV	0.0018	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742