EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000143319 (Gene tree)
Gene ID: 81875
Gene Symbol: ISG20L2
Alias: FLJ12671
Full Name: interferon stimulated exonuclease gene 20 like 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 6,909 bases
Position: chr1:156,721,891-156,728,799
Accession: 25745
RBP type: canonical RBP
Summary: This gene encodes a 3'-5' exoribonuclease that may be involved in the processing of the 12S pre-rRNA. Pseudogenes have been identified on chromosomes 6 and 11. [provided by RefSeq, Dec 2014]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000323424	RNase_T	PF00929.24	1.4e-11	1	1
ENSP00000357202	RNase_T	PF00929.24	1.4e-11	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000368219	ISG20L2-202	2310	XM_005245516	ENSP00000357202	353 (aa)	XP_005245573	Q9H9L3
ENST00000469074	ISG20L2-203	594	-	-	- (aa)	-	-
ENST00000496538	ISG20L2-206	872	-	-	- (aa)	-	-
ENST00000313146	ISG20L2-201	3303	XM_006711561	ENSP00000323424	353 (aa)	XP_006711624	Q9H9L3
ENST00000470713	ISG20L2-204	635	-	-	- (aa)	-	-
ENST00000472824	ISG20L2-205	3178	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000143319's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000143319's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000143319	ISG20L2	51	61.453	ENSG00000181026	AEN	55	61.453

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000143319	ISG20L2	50	63.068	ENSAPOG00000021246	ISG20L2	54	63.068	Acanthochromis_polyacanthus
ENSG00000143319	ISG20L2	100	85.269	ENSAMEG00000014923	ISG20L2	100	85.269	Ailuropoda_melanoleuca
ENSG00000143319	ISG20L2	57	51.923	ENSACIG00000006718	ISG20L2	89	63.636	Amphilophus_citrinellus
ENSG00000143319	ISG20L2	52	60.989	ENSAOCG00000010441	ISG20L2	57	60.317	Amphiprion_ocellaris
ENSG00000143319	ISG20L2	54	60.317	ENSAPEG00000003143	ISG20L2	57	60.317	Amphiprion_percula
ENSG00000143319	ISG20L2	50	64.773	ENSATEG00000020411	ISG20L2	56	64.773	Anabas_testudineus
ENSG00000143319	ISG20L2	100	47.837	ENSACAG00000015444	ISG20L2	100	47.837	Anolis_carolinensis
ENSG00000143319	ISG20L2	100	92.918	ENSANAG00000026649	ISG20L2	100	92.918	Aotus_nancymaae
ENSG00000143319	ISG20L2	100	87.006	ENSBTAG00000001518	ISG20L2	100	87.006	Bos_taurus
ENSG00000143319	ISG20L2	100	92.918	ENSCJAG00000006126	ISG20L2	100	92.918	Callithrix_jacchus
ENSG00000143319	ISG20L2	100	86.686	ENSCAFG00000016753	ISG20L2	100	86.686	Canis_familiaris
ENSG00000143319	ISG20L2	100	86.686	ENSCAFG00020005209	-	100	86.686	Canis_lupus_dingo
ENSG00000143319	ISG20L2	100	87.819	ENSCHIG00000024024	ISG20L2	100	87.819	Capra_hircus
ENSG00000143319	ISG20L2	100	90.678	ENSTSYG00000035073	ISG20L2	100	90.678	Carlito_syrichta
ENSG00000143319	ISG20L2	99	71.507	ENSCAPG00000002077	ISG20L2	99	72.603	Cavia_aperea
ENSG00000143319	ISG20L2	99	76.602	ENSCPOG00000038074	ISG20L2	99	77.716	Cavia_porcellus
ENSG00000143319	ISG20L2	100	92.351	ENSCCAG00000023874	ISG20L2	100	92.351	Cebus_capucinus
ENSG00000143319	ISG20L2	100	96.893	ENSCATG00000003077	-	100	96.893	Cercocebus_atys
ENSG00000143319	ISG20L2	100	87.006	ENSCATG00000044219	-	100	87.006	Cercocebus_atys
ENSG00000143319	ISG20L2	99	80.057	ENSCLAG00000003281	ISG20L2	100	79.603	Chinchilla_lanigera
ENSG00000143319	ISG20L2	100	97.450	ENSCSAG00000002177	ISG20L2	100	97.450	Chlorocebus_sabaeus
ENSG00000143319	ISG20L2	99	49.030	ENSCPBG00000026287	ISG20L2	99	50.139	Chrysemys_picta_bellii
ENSG00000143319	ISG20L2	100	96.610	ENSCANG00000034018	-	100	96.610	Colobus_angolensis_palliatus
ENSG00000143319	ISG20L2	100	89.518	ENSCANG00000032356	-	100	89.518	Colobus_angolensis_palliatus
ENSG00000143319	ISG20L2	100	75.067	ENSCGRG00001020551	Isg20l2	100	73.656	Cricetulus_griseus_chok1gshd
ENSG00000143319	ISG20L2	100	75.067	ENSCGRG00000015836	Isg20l2	100	73.656	Cricetulus_griseus_crigri
ENSG00000143319	ISG20L2	51	57.459	ENSCSEG00000000743	ISG20L2	98	58.621	Cynoglossus_semilaevis
ENSG00000143319	ISG20L2	98	44.034	ENSCVAG00000019762	-	99	41.834	Cyprinodon_variegatus
ENSG00000143319	ISG20L2	100	87.006	ENSDNOG00000018167	ISG20L2	100	87.006	Dasypus_novemcinctus
ENSG00000143319	ISG20L2	100	76.771	ENSDORG00000013737	Isg20l2	100	75.354	Dipodomys_ordii
ENSG00000143319	ISG20L2	100	87.571	ENSEASG00005018271	ISG20L2	100	87.571	Equus_asinus_asinus
ENSG00000143319	ISG20L2	100	87.853	ENSECAG00000015891	ISG20L2	100	87.853	Equus_caballus
ENSG00000143319	ISG20L2	98	47.309	ENSELUG00000001149	-	98	47.042	Esox_lucius
ENSG00000143319	ISG20L2	100	85.836	ENSFCAG00000006559	ISG20L2	100	85.836	Felis_catus
ENSG00000143319	ISG20L2	100	78.754	ENSFDAG00000008285	ISG20L2	90	78.754	Fukomys_damarensis
ENSG00000143319	ISG20L2	58	57.820	ENSGAFG00000012507	-	96	63.953	Gambusia_affinis
ENSG00000143319	ISG20L2	99	50.140	ENSGAGG00000023201	ISG20L2	99	47.792	Gopherus_agassizii
ENSG00000143319	ISG20L2	100	99.153	ENSGGOG00000016482	ISG20L2	100	99.153	Gorilla_gorilla
ENSG00000143319	ISG20L2	99	80.342	ENSHGLG00000019533	ISG20L2	100	79.887	Heterocephalus_glaber_female
ENSG00000143319	ISG20L2	99	79.487	ENSHGLG00100014241	ISG20L2	100	79.037	Heterocephalus_glaber_male
ENSG00000143319	ISG20L2	99	45.634	ENSIPUG00000006645	isg20l2	57	67.816	Ictalurus_punctatus
ENSG00000143319	ISG20L2	99	80.912	ENSSTOG00000007733	ISG20L2	100	79.603	Ictidomys_tridecemlineatus
ENSG00000143319	ISG20L2	55	62.051	ENSKMAG00000016622	ISG20L2	59	62.051	Kryptolebias_marmoratus
ENSG00000143319	ISG20L2	100	82.768	ENSLAFG00000016415	ISG20L2	100	82.203	Loxodonta_africana
ENSG00000143319	ISG20L2	100	97.175	ENSMFAG00000044153	-	100	97.175	Macaca_fascicularis
ENSG00000143319	ISG20L2	91	86.997	ENSMFAG00000032348	-	100	86.997	Macaca_fascicularis
ENSG00000143319	ISG20L2	100	97.175	ENSMMUG00000000037	ISG20L2	100	97.175	Macaca_mulatta
ENSG00000143319	ISG20L2	100	85.876	ENSMMUG00000044752	-	100	85.876	Macaca_mulatta
ENSG00000143319	ISG20L2	100	96.893	ENSMNEG00000038472	-	100	96.893	Macaca_nemestrina
ENSG00000143319	ISG20L2	91	86.687	ENSMNEG00000005740	-	100	86.687	Macaca_nemestrina
ENSG00000143319	ISG20L2	100	96.893	ENSMLEG00000027957	-	100	96.893	Mandrillus_leucophaeus
ENSG00000143319	ISG20L2	71	68.045	ENSMAUG00000017352	Isg20l2	100	67.669	Mesocricetus_auratus
ENSG00000143319	ISG20L2	100	92.090	ENSMICG00000008929	ISG20L2	100	92.090	Microcebus_murinus
ENSG00000143319	ISG20L2	100	71.618	ENSMOCG00000000875	Isg20l2	100	70.292	Microtus_ochrogaster
ENSG00000143319	ISG20L2	99	55.028	ENSMODG00000016797	ISG20L2	99	55.028	Monodelphis_domestica
ENSG00000143319	ISG20L2	50	63.636	ENSMALG00000005859	ISG20L2	56	61.957	Monopterus_albus
ENSG00000143319	ISG20L2	100	71.622	MGP_CAROLIEiJ_G0025147	Isg20l2	100	72.162	Mus_caroli
ENSG00000143319	ISG20L2	100	71.816	ENSMUSG00000048039	Isg20l2	100	71.274	Mus_musculus
ENSG00000143319	ISG20L2	100	72.703	MGP_PahariEiJ_G0026590	Isg20l2	100	72.703	Mus_pahari
ENSG00000143319	ISG20L2	100	70.000	MGP_SPRETEiJ_G0026088	Isg20l2	100	70.000	Mus_spretus
ENSG00000143319	ISG20L2	100	82.436	ENSMPUG00000004066	ISG20L2	100	82.436	Mustela_putorius_furo
ENSG00000143319	ISG20L2	100	83.616	ENSMLUG00000026163	ISG20L2	100	83.616	Myotis_lucifugus
ENSG00000143319	ISG20L2	99	79.487	ENSNGAG00000000756	Isg20l2	100	78.470	Nannospalax_galili
ENSG00000143319	ISG20L2	100	97.175	ENSNLEG00000012742	ISG20L2	100	97.175	Nomascus_leucogenys
ENSG00000143319	ISG20L2	100	77.183	ENSOPRG00000000639	ISG20L2	100	78.028	Ochotona_princeps
ENSG00000143319	ISG20L2	99	77.493	ENSODEG00000009003	ISG20L2	99	76.989	Octodon_degus
ENSG00000143319	ISG20L2	100	82.153	ENSOCUG00000001459	ISG20L2	100	82.153	Oryctolagus_cuniculus
ENSG00000143319	ISG20L2	95	47.929	ENSORLG00020000438	-	93	47.929	Oryzias_latipes_hni
ENSG00000143319	ISG20L2	95	46.131	ENSORLG00015022560	ISG20L2	93	45.833	Oryzias_latipes_hsok
ENSG00000143319	ISG20L2	96	47.788	ENSOMEG00000022394	-	94	47.493	Oryzias_melastigma
ENSG00000143319	ISG20L2	100	88.136	ENSOGAG00000016818	ISG20L2	100	88.136	Otolemur_garnettii
ENSG00000143319	ISG20L2	100	87.535	ENSOARG00000006234	ISG20L2	100	87.535	Ovis_aries
ENSG00000143319	ISG20L2	100	99.433	ENSPPAG00000031075	ISG20L2	100	99.433	Pan_paniscus
ENSG00000143319	ISG20L2	100	84.986	ENSPPRG00000017476	ISG20L2	100	84.986	Panthera_pardus
ENSG00000143319	ISG20L2	100	84.986	ENSPTIG00000020421	ISG20L2	100	84.986	Panthera_tigris_altaica
ENSG00000143319	ISG20L2	100	99.717	ENSPTRG00000001471	ISG20L2	100	99.717	Pan_troglodytes
ENSG00000143319	ISG20L2	100	96.893	ENSPANG00000019805	-	100	96.893	Papio_anubis
ENSG00000143319	ISG20L2	100	87.571	ENSPANG00000024433	-	100	87.571	Papio_anubis
ENSG00000143319	ISG20L2	99	43.902	ENSPKIG00000010547	ISG20L2	98	43.956	Paramormyrops_kingsleyae
ENSG00000143319	ISG20L2	99	48.011	ENSPSIG00000007349	ISG20L2	99	48.011	Pelodiscus_sinensis
ENSG00000143319	ISG20L2	100	73.190	ENSPEMG00000005960	Isg20l2	100	73.995	Peromyscus_maniculatus_bairdii
ENSG00000143319	ISG20L2	99	58.217	ENSPCIG00000024239	ISG20L2	99	58.217	Phascolarctos_cinereus
ENSG00000143319	ISG20L2	50	64.972	ENSPMEG00000012377	ISG20L2	98	64.972	Poecilia_mexicana
ENSG00000143319	ISG20L2	94	42.012	ENSPREG00000018640	-	93	42.029	Poecilia_reticulata
ENSG00000143319	ISG20L2	100	98.588	ENSPPYG00000000706	ISG20L2	100	98.588	Pongo_abelii
ENSG00000143319	ISG20L2	90	79.811	ENSPCAG00000012592	ISG20L2	100	79.811	Procavia_capensis
ENSG00000143319	ISG20L2	100	91.525	ENSPCOG00000017546	ISG20L2	100	91.525	Propithecus_coquereli
ENSG00000143319	ISG20L2	90	81.013	ENSPVAG00000007510	ISG20L2	100	81.013	Pteropus_vampyrus
ENSG00000143319	ISG20L2	98	44.382	ENSPNAG00000002285	ISG20L2	98	44.886	Pygocentrus_nattereri
ENSG00000143319	ISG20L2	100	72.533	ENSRNOG00000011402	Isg20l2	100	72.162	Rattus_norvegicus
ENSG00000143319	ISG20L2	100	90.960	ENSRBIG00000030897	-	100	90.960	Rhinopithecus_bieti
ENSG00000143319	ISG20L2	100	91.808	ENSRBIG00000034100	-	99	96.181	Rhinopithecus_bieti
ENSG00000143319	ISG20L2	100	96.610	ENSRROG00000036240	ISG20L2	100	96.610	Rhinopithecus_roxellana
ENSG00000143319	ISG20L2	100	92.351	ENSSBOG00000035666	ISG20L2	100	92.351	Saimiri_boliviensis_boliviensis
ENSG00000143319	ISG20L2	99	57.103	ENSSHAG00000015943	ISG20L2	99	56.983	Sarcophilus_harrisii
ENSG00000143319	ISG20L2	56	58.376	ENSSMAG00000016020	-	62	58.376	Scophthalmus_maximus
ENSG00000143319	ISG20L2	64	56.195	ENSSDUG00000015054	-	55	61.140	Seriola_dumerili
ENSG00000143319	ISG20L2	64	56.195	ENSSLDG00000017835	-	55	61.140	Seriola_lalandi_dorsalis
ENSG00000143319	ISG20L2	100	75.637	ENSSARG00000000088	ISG20L2	100	75.071	Sorex_araneus
ENSG00000143319	ISG20L2	50	65.169	ENSSPAG00000006538	ISG20L2	55	65.169	Stegastes_partitus
ENSG00000143319	ISG20L2	100	85.836	ENSSSCG00000006471	ISG20L2	100	85.836	Sus_scrofa
ENSG00000143319	ISG20L2	50	63.068	ENSTNIG00000012980	ISG20L2	56	63.068	Tetraodon_nigroviridis
ENSG00000143319	ISG20L2	100	80.791	ENSTBEG00000015022	ISG20L2	100	80.791	Tupaia_belangeri
ENSG00000143319	ISG20L2	100	79.603	ENSTTRG00000014509	ISG20L2	100	79.320	Tursiops_truncatus
ENSG00000143319	ISG20L2	100	84.986	ENSUAMG00000013421	ISG20L2	100	84.986	Ursus_americanus
ENSG00000143319	ISG20L2	100	84.986	ENSUMAG00000017767	ISG20L2	100	84.986	Ursus_maritimus
ENSG00000143319	ISG20L2	81	91.892	ENSVPAG00000007483	ISG20L2	81	91.892	Vicugna_pacos
ENSG00000143319	ISG20L2	100	86.686	ENSVVUG00000006071	ISG20L2	100	86.686	Vulpes_vulpes
ENSG00000143319	ISG20L2	51	63.333	ENSXCOG00000004522	ISG20L2	89	63.333	Xiphophorus_couchianus
ENSG00000143319	ISG20L2	58	56.667	ENSXMAG00000013246	-	52	64.535	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000175	3'-5'-exoribonuclease activity	18065403.	EXP	Function
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	16189514.17474147.19060904.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IEA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	-	IEA	Process