EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000143373 (Gene tree)
Gene ID: 57592
Gene Symbol: ZNF687
Alias: KIAA1441
Full Name: zinc finger protein 687
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 10,626 bases
Position: chr1:151,281,555-151,292,180
Accession: 29277
RBP type: canonical RBP
Summary: This gene encodes C2H2 zinc finger protein. The encoded protein may play a role in bone differentiation and development. Mutations in this gene are the cause of Paget disease of bone-6. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000319829	zf-C2H2	PF00096.26	7.7e-14	1	2
ENSP00000319829	zf-C2H2	PF00096.26	7.7e-14	2	2
ENSP00000336620	zf-C2H2	PF00096.26	7.7e-14	1	2
ENSP00000336620	zf-C2H2	PF00096.26	7.7e-14	2	2
ENSP00000398821	zf-C2H2	PF00096.26	2.1e-09	1	1
ENSP00000319829	zf-met	PF12874.7	1.6e-05	1	1
ENSP00000336620	zf-met	PF12874.7	1.6e-05	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000426871	ZNF687-203	3277	-	ENSP00000398821	706 (aa)	-	H0Y5I5
ENST00000459919	ZNF687-207	840	-	-	- (aa)	-	-
ENST00000443959	ZNF687-205	893	-	ENSP00000395261	147 (aa)	-	A2A3Q2
ENST00000324048	ZNF687-201	5378	-	ENSP00000319829	1237 (aa)	-	Q8N1G0
ENST00000449313	ZNF687-206	4185	-	ENSP00000415286	785 (aa)	-	F8WCX2
ENST00000336715	ZNF687-202	4831	XM_005245366	ENSP00000336620	1237 (aa)	XP_005245423	Q8N1G0
ENST00000436614	ZNF687-204	766	-	ENSP00000416942	99 (aa)	-	A6PVV7

Gene Model

Click here to download ENSG00000143373's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000143373's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000143373	ZNF687	100	88.468	ENSAMEG00000000725	ZNF687	100	88.306	Ailuropoda_melanoleuca
ENSG00000143373	ZNF687	100	95.557	ENSANAG00000025948	ZNF687	100	95.396	Aotus_nancymaae
ENSG00000143373	ZNF687	100	90.638	ENSBTAG00000007318	ZNF687	100	90.638	Bos_taurus
ENSG00000143373	ZNF687	100	94.992	ENSCJAG00000033395	ZNF687	100	94.830	Callithrix_jacchus
ENSG00000143373	ZNF687	100	88.629	ENSCAFG00000012605	ZNF687	100	88.468	Canis_familiaris
ENSG00000143373	ZNF687	100	88.629	ENSCAFG00020012909	ZNF687	100	88.468	Canis_lupus_dingo
ENSG00000143373	ZNF687	100	91.935	ENSTSYG00000033410	ZNF687	100	91.774	Carlito_syrichta
ENSG00000143373	ZNF687	100	84.045	ENSCAPG00000017697	ZNF687	100	83.642	Cavia_aperea
ENSG00000143373	ZNF687	100	85.415	ENSCPOG00000010631	ZNF687	100	85.012	Cavia_porcellus
ENSG00000143373	ZNF687	100	95.153	ENSCCAG00000036501	ZNF687	100	94.992	Cebus_capucinus
ENSG00000143373	ZNF687	100	97.979	ENSCATG00000000360	ZNF687	100	97.979	Cercocebus_atys
ENSG00000143373	ZNF687	100	86.463	ENSCLAG00000000787	ZNF687	100	86.301	Chinchilla_lanigera
ENSG00000143373	ZNF687	68	97.495	ENSCSAG00000001797	ZNF687	100	98.825	Chlorocebus_sabaeus
ENSG00000143373	ZNF687	100	97.332	ENSCANG00000037537	ZNF687	100	97.332	Colobus_angolensis_palliatus
ENSG00000143373	ZNF687	100	84.875	ENSCGRG00001011676	Zfp687	100	84.232	Cricetulus_griseus_chok1gshd
ENSG00000143373	ZNF687	100	84.875	ENSCGRG00000010527	Zfp687	100	84.232	Cricetulus_griseus_crigri
ENSG00000143373	ZNF687	100	91.855	ENSDNOG00000046703	ZNF687	100	91.694	Dasypus_novemcinctus
ENSG00000143373	ZNF687	89	95.231	ENSEASG00005002145	ZNF687	100	91.765	Equus_asinus_asinus
ENSG00000143373	ZNF687	100	90.726	ENSECAG00000006072	ZNF687	100	90.000	Equus_caballus
ENSG00000143373	ZNF687	100	87.823	ENSFCAG00000005566	ZNF687	100	86.452	Felis_catus
ENSG00000143373	ZNF687	100	99.030	ENSGGOG00000015144	ZNF687	100	99.030	Gorilla_gorilla
ENSG00000143373	ZNF687	100	86.774	ENSHGLG00000009054	ZNF687	100	87.016	Heterocephalus_glaber_female
ENSG00000143373	ZNF687	100	90.403	ENSSTOG00000023367	ZNF687	100	90.242	Ictidomys_tridecemlineatus
ENSG00000143373	ZNF687	100	91.935	ENSLAFG00000030899	ZNF687	100	91.774	Loxodonta_africana
ENSG00000143373	ZNF687	100	97.575	ENSMFAG00000034438	ZNF687	100	97.575	Macaca_fascicularis
ENSG00000143373	ZNF687	100	97.736	ENSMMUG00000013166	ZNF687	100	97.736	Macaca_mulatta
ENSG00000143373	ZNF687	100	97.656	ENSMNEG00000034210	ZNF687	100	97.656	Macaca_nemestrina
ENSG00000143373	ZNF687	100	97.979	ENSMLEG00000024831	ZNF687	100	97.979	Mandrillus_leucophaeus
ENSG00000143373	ZNF687	100	83.977	ENSMAUG00000004550	Zfp687	100	83.333	Mesocricetus_auratus
ENSG00000143373	ZNF687	100	88.245	ENSMICG00000016128	ZNF687	100	88.084	Microcebus_murinus
ENSG00000143373	ZNF687	100	86.484	MGP_CAROLIEiJ_G0025323	Zfp687	100	85.749	Mus_caroli
ENSG00000143373	ZNF687	100	85.921	ENSMUSG00000019338	Zfp687	100	85.185	Mus_musculus
ENSG00000143373	ZNF687	100	85.173	MGP_PahariEiJ_G0026767	Zfp687	100	85.093	Mus_pahari
ENSG00000143373	ZNF687	100	86.082	MGP_SPRETEiJ_G0026267	Zfp687	100	85.346	Mus_spretus
ENSG00000143373	ZNF687	100	88.710	ENSMPUG00000003797	ZNF687	100	88.548	Mustela_putorius_furo
ENSG00000143373	ZNF687	100	86.301	ENSNGAG00000017739	Zfp687	100	85.576	Nannospalax_galili
ENSG00000143373	ZNF687	100	98.060	ENSNLEG00000010154	ZNF687	100	98.060	Nomascus_leucogenys
ENSG00000143373	ZNF687	100	86.371	ENSODEG00000010274	ZNF687	100	86.210	Octodon_degus
ENSG00000143373	ZNF687	100	89.326	ENSOCUG00000027462	ZNF687	100	87.881	Oryctolagus_cuniculus
ENSG00000143373	ZNF687	100	86.855	ENSOGAG00000032200	ZNF687	100	85.161	Otolemur_garnettii
ENSG00000143373	ZNF687	100	99.596	ENSPPAG00000027876	ZNF687	100	99.596	Pan_paniscus
ENSG00000143373	ZNF687	100	88.145	ENSPPRG00000003190	ZNF687	100	86.774	Panthera_pardus
ENSG00000143373	ZNF687	100	87.440	ENSPTIG00000007625	ZNF687	100	86.071	Panthera_tigris_altaica
ENSG00000143373	ZNF687	100	99.677	ENSPTRG00000001284	ZNF687	100	99.677	Pan_troglodytes
ENSG00000143373	ZNF687	100	97.979	ENSPANG00000003115	ZNF687	100	97.979	Papio_anubis
ENSG00000143373	ZNF687	100	85.048	ENSPEMG00000016093	Zfp687	100	85.209	Peromyscus_maniculatus_bairdii
ENSG00000143373	ZNF687	100	98.383	ENSPPYG00000000869	ZNF687	100	98.383	Pongo_abelii
ENSG00000143373	ZNF687	100	88.790	ENSPCAG00000010893	ZNF687	100	87.742	Procavia_capensis
ENSG00000143373	ZNF687	100	89.032	ENSPCOG00000024950	ZNF687	100	88.871	Propithecus_coquereli
ENSG00000143373	ZNF687	86	86.929	ENSPVAG00000011674	ZNF687	86	86.929	Pteropus_vampyrus
ENSG00000143373	ZNF687	100	85.829	ENSRNOG00000021026	Zfp687	100	84.863	Rattus_norvegicus
ENSG00000143373	ZNF687	100	97.575	ENSRBIG00000028192	ZNF687	100	97.575	Rhinopithecus_bieti
ENSG00000143373	ZNF687	100	97.736	ENSRROG00000037226	ZNF687	100	97.736	Rhinopithecus_roxellana
ENSG00000143373	ZNF687	100	95.153	ENSSBOG00000036275	ZNF687	100	94.992	Saimiri_boliviensis_boliviensis
ENSG00000143373	ZNF687	100	90.499	ENSSSCG00000006627	ZNF687	100	90.338	Sus_scrofa
ENSG00000143373	ZNF687	100	90.806	ENSTTRG00000007020	ZNF687	100	90.645	Tursiops_truncatus
ENSG00000143373	ZNF687	100	89.435	ENSUAMG00000027445	ZNF687	100	89.435	Ursus_americanus
ENSG00000143373	ZNF687	100	88.468	ENSVVUG00000012829	ZNF687	100	88.306	Vulpes_vulpes
ENSG00000143373	ZNF687	89	63.206	ENSXETG00000010001	znf687	59	60.669	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005515	protein binding	26496610.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr1	151289504	Silent	rs762887000	L866L	0.3
BLCA	chr1	151287108	Missense_Mutation	novel	L273F	0.09
BLCA	chr1	151287655	Missense_Mutation	rs755339101	R455Q	0.48
BLCA	chr1	151287304	Missense_Mutation	rs778316550	S338C	0.23
BLCA	chr1	151289384	Silent	rs750441352	I826I	0.3
BLCA	chr1	151291040	Nonsense_Mutation	NA	S1182*	0.27
BLCA	chr1	151287338	Silent	NA	V349V	0.4
BLCA	chr1	151287892	Missense_Mutation	novel	R534H	0.23
BLCA	chr1	151286549	Silent	novel	V86V	0.15
BLCA	chr1	151288173	Silent	novel	L628L	0.58
BLCA	chr1	151286319	Missense_Mutation	NA	D10H	0.62
BLCA	chr1	151290429	Splice_Region	novel		0.24
BLCA	chr1	151287884	Silent	rs142842127	T531T	0.17
BLCA	chr1	151289822	Missense_Mutation	NA	E927K	0.38
BLCA	chr1	151289208	Missense_Mutation	novel	S803C	0.1
BLCA	chr1	151291140	Silent	novel	L1215L	0.16
BRCA	chr1	151289851	Frame_Shift_Ins	rs749403447	*R939Pfs36**	0.21
BRCA	chr1	151289414	Missense_Mutation	NA	F836L	0.19
BRCA	chr1	151290459	Silent	novel	F1035F	0.23
BRCA	chr1	151289411	Silent	novel	V835V	0.06
BRCA	chr1	151286538	Missense_Mutation	novel	S83G	0.06
BRCA	chr1	151288182	Missense_Mutation	NA	P631S	0.22
BRCA	chr1	151286693	Silent	NA	L134L	0.11
BRCA	chr1	151290235	Splice_Site	novel	X1026_splice	0.13
BRCA	chr1	151289512	Missense_Mutation	NA	Q869R	0.11
BRCA	chr1	151289989	Missense_Mutation	NA	M982I	0.19
BRCA	chr1	151286772	Missense_Mutation	NA	D161N	0.45
BRCA	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.16
BRCA	chr1	151287413	Silent	NA	S374S	0.34
BRCA	chr1	151288660	Missense_Mutation	NA	H750N	0.24
BRCA	chr1	151287032	Silent	rs752925191	D247D	0.18
BRCA	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.15
BRCA	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.35
CESC	chr1	151291549	3'UTR	novel		0.32
CESC	chr1	151290442	Missense_Mutation	NA	E1030Q	0.2
CESC	chr1	151280219	5'Flank	novel		0.35
CESC	chr1	151288378	Missense_Mutation	novel	G696D	0.37
CESC	chr1	151290801	Silent	rs373263821	G1102G	0.36
CESC	chr1	151286537	Silent	novel	V82V	0.56
CESC	chr1	151281628	5'Flank	novel		0.15
CESC	chr1	151291739	3'UTR	novel		0.38
CESC	chr1	151291596	3'UTR	novel		0.28
CESC	chr1	151287096	Missense_Mutation	NA	H269Y	0.21
CESC	chr1	151290730	Missense_Mutation	novel	R1079C	0.55
COAD	chr1	151289915	Frame_Shift_Del	NA	*P960Lfs23**	0.3
COAD	chr1	151290488	Missense_Mutation	NA	V1045A	0.37
COAD	chr1	151287402	Silent	novel	L371L	0.34
COAD	chr1	151288075	Missense_Mutation	novel	S595L	0.3
COAD	chr1	151288202	Frame_Shift_Del	novel	*A639Pfs74**	0.27
COAD	chr1	151288649	Missense_Mutation	novel	N746I	0.24
COAD	chr1	151289182	Silent	novel	C794C	0.24
COAD	chr1	151289853	Missense_Mutation	rs148402804	P937H	0.34
COAD	chr1	151280174	5'Flank	novel		0.1
COAD	chr1	151288585	Missense_Mutation	rs756753926	R725C	0.32
COAD	chr1	151287312	Missense_Mutation	novel	N341D	0.54
COAD	chr1	151287552	Missense_Mutation	novel	R421C	0.38
COAD	chr1	151290533	Missense_Mutation	rs587678192	R1060Q	0.22
COAD	chr1	151286363	Silent	NA	N24N	0.26
COAD	chr1	151288692	Silent	NA	R760R	0.24
COAD	chr1	151286290	5'UTR	novel		0.25
COAD	chr1	151289512	Frame_Shift_Del	novel	*R871Gfs29**	0.1
COAD	chr1	151288074	Missense_Mutation	novel	S595P	0.07
COAD	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.58
COAD	chr1	151287389	Silent	novel	A366A	0.27
COAD	chr1	151290206	Missense_Mutation	novel	E1017K	0.31
COAD	chr1	151289852	Frame_Shift_Del	NA	*R939Vfs10**	0.08
COAD	chr1	151290498	Silent	NA	R1048R	0.27
COAD	chr1	151287993	Missense_Mutation	rs760248301	R568C	0.27
ESCA	chr1	151288697	Missense_Mutation	novel	V762A	0.31
ESCA	chr1	151289915	Frame_Shift_Del	NA	*P960Lfs23**	0.28
ESCA	chr1	151291739	3'UTR	novel		0.27
ESCA	chr1	151288601	Missense_Mutation	rs375351311	R730Q	0.35
ESCA	chr1	151281848	5'Flank	novel		0.29
GBM	chr1	151286977	Frame_Shift_Del	novel	*H229Lfs5**	0.09
GBM	chr1	151286804	Silent	novel	G171G	0.33
GBM	chr1	151287088	Missense_Mutation	novel	S266F	0.08
GBM	chr1	151287377	Silent	novel	G362G	0.14
GBM	chr1	151287979	Missense_Mutation	novel	C563Y	0.1
GBM	chr1	151286482	Frame_Shift_Del	novel	*V65Sfs6**	0.16
HNSC	chr1	151287348	Missense_Mutation	novel	P353S	0.31
HNSC	chr1	151287265	Missense_Mutation	novel	S325Y	0.13
HNSC	chr1	151287969	Missense_Mutation	NA	E560K	0.14
HNSC	chr1	151286995	Missense_Mutation	novel	A235V	0.22
HNSC	chr1	151288544	Missense_Mutation	novel	P711L	0.16
HNSC	chr1	151288545	Silent	novel	P711P	0.16
HNSC	chr1	151288546	Frame_Shift_Ins	novel	*M712Ifs17**	0.26
HNSC	chr1	151286418	Missense_Mutation	novel	P43S	0.18
HNSC	chr1	151287213	Missense_Mutation	novel	G308W	0.39
HNSC	chr1	151287214	Missense_Mutation	novel	G308V	0.4
HNSC	chr1	151288049	Silent	NA	K586K	0.21
HNSC	chr1	151288274	Silent	rs777443857	P661P	0.19
KIRC	chr1	151287342	Missense_Mutation	NA	S351P	0.38
KIRC	chr1	151290942	Silent	NA	S1149S	0.34
KIRC	chr1	151286871	Missense_Mutation	NA	P194A	0.29
KIRP	chr1	151286897	Silent	NA	A202A	0.47
KIRP	chr1	151288340	Silent	novel	R683R	0.54
KIRP	chr1	151289137	Missense_Mutation	novel	I779M	0.05
KIRP	chr1	151288664	Missense_Mutation	NA	L751R	0.22
KIRP	chr1	151286763	Missense_Mutation	novel	T158A	0.44
LAML	chr1	151286354	Silent	novel	I21I	0.2
LAML	chr1	151287951	Missense_Mutation	NA	R554C	0.27
LGG	chr1	151289944	Silent	rs199686732	L967L	0.37
LGG	chr1	151290774	Silent	rs201368023	T1093T	0.47
LGG	chr1	151286441	Silent	NA	E50E	0.38
LGG	chr1	151288575	Silent	rs763463975	S721S	0.3
LGG	chr1	151289402	Silent	rs146722973	C832C	0.52
LIHC	chr1	151286356	Missense_Mutation	novel	D22G	0.16
LIHC	chr1	151286464	Missense_Mutation	rs762937626	S58F	0.51
LIHC	chr1	151286697	Frame_Shift_Del	novel	*G136Efs55**	0.33
LIHC	chr1	151290153	Frame_Shift_Ins	novel	*R1000Afs16**	0.19
LIHC	chr1	151287914	Silent	novel	A541A	0.41
LIHC	chr1	151289520	Frame_Shift_Ins	novel	*M873Hfs32**	0.44
LIHC	chr1	151289975	Missense_Mutation	novel	Y978N	0.17
LIHC	chr1	151287531	Silent	NA	L414L	0.37
LIHC	chr1	151289128	Silent	novel	V776V	0.05
LIHC	chr1	151286607	Missense_Mutation	novel	G106W	0.12
LIHC	chr1	151289851	Frame_Shift_Ins	rs749403447	*R939Pfs36**	0.2
LUAD	chr1	151287308	Silent	rs141982116	C339C	0.11
LUAD	chr1	151287476	Silent	NA	R395R	0.28
LUAD	chr1	151289191	Silent	NA	C797C	0.05
LUAD	chr1	151290801	Silent	rs373263821	G1102G	0.16
LUAD	chr1	151288290	Missense_Mutation	novel	T667S	0.24
LUAD	chr1	151288259	Silent	rs371085557	P656P	0.11
LUAD	chr1	151289243	Missense_Mutation	novel	H815Y	0.17
LUAD	chr1	151288683	Silent	rs760512566	H757H	0.17
LUAD	chr1	151287968	Missense_Mutation	NA	I559M	0.36
LUAD	chr1	151287587	Silent	novel	T432T	0.46
LUSC	chr1	151288630	Missense_Mutation	novel	G740S	0.09
LUSC	chr1	151288338	Missense_Mutation	rs587752645	R683W	0.19
LUSC	chr1	151287750	Missense_Mutation	NA	G487R	0.28
LUSC	chr1	151290168	Missense_Mutation	NA	S1004F	0.41
LUSC	chr1	151286607	Missense_Mutation	novel	G106W	0.49
LUSC	chr1	151288161	Missense_Mutation	novel	V624I	0.15
LUSC	chr1	151290779	Missense_Mutation	rs376641944	P1095L	0.36
LUSC	chr1	151286432	Silent	novel	V47V	0.46
LUSC	chr1	151290807	Silent	novel	P1104P	0.27
LUSC	chr1	151287049	Missense_Mutation	rs745647931	S253L	0.03
MESO	chr1	151291199	Missense_Mutation	novel	G1235E	0.37
OV	chr1	151286708	Missense_Mutation	novel	H139Q	0.21
OV	chr1	151286436	Missense_Mutation	novel	S49C	0.05
OV	chr1	151291074	Silent	novel	L1193L	0.16
OV	chr1	151287137	Missense_Mutation	novel	Q282H	0.04
OV	chr1	151288634	Missense_Mutation	rs781593158	N741S	0.6
OV	chr1	151286431	Missense_Mutation	novel	V47E	0.09
OV	chr1	151286796	Missense_Mutation	NA	E169K	0.6
OV	chr1	151287004	In_Frame_Del	NA	S239_S242del	0.33
OV	chr1	151286286	5'UTR	novel		0.28
PAAD	chr1	151286570	Missense_Mutation	novel	E93D	0.15
PAAD	chr1	151290482	Missense_Mutation	novel	K1043T	0.12
PAAD	chr1	151290797	Missense_Mutation	novel	R1101K	0.18
PCPG	chr1	151288182	Missense_Mutation	NA	P631S	0.32
PRAD	chr1	151288404	Frame_Shift_Del	novel	*N705Mfs8**	0.3
PRAD	chr1	151291122	Silent	rs150478719	C1209C	0.19
READ	chr1	151281598	5'Flank	novel		0.52
READ	chr1	151287905	Missense_Mutation	novel	C538W	0.17
READ	chr1	151289523	Missense_Mutation	novel	M873V	0.09
READ	chr1	151290721	Missense_Mutation	NA	G1076S	0.18
SARC	chr1	151290524	Missense_Mutation	novel	S1057F	0.27
SARC	chr1	151280087	5'Flank	novel		0.81
SKCM	chr1	151289227	Silent	novel	A809A	0.21
SKCM	chr1	151289228	Missense_Mutation	novel	H810Y	0.21
SKCM	chr1	151286530	Missense_Mutation	novel	S80F	0.45
SKCM	chr1	151287076	Missense_Mutation	NA	F262Y	0.2
SKCM	chr1	151287287	Silent	novel	I332I	0.33
SKCM	chr1	151288340	Silent	novel	R683R	0.2
SKCM	chr1	151287208	Missense_Mutation	NA	S306F	0.49
SKCM	chr1	151286916	Missense_Mutation	NA	M209L	0.3
SKCM	chr1	151289533	Missense_Mutation	NA	H876R	0.18
SKCM	chr1	151287026	Silent	novel	A245A	0.28
SKCM	chr1	151288701	Silent	NA	G763G	0.13
SKCM	chr1	151286876	Silent	novel	F195F	0.16
SKCM	chr1	151290446	Missense_Mutation	NA	G1031E	0.2
SKCM	chr1	151286826	Missense_Mutation	rs367789129	P179S	0.15
SKCM	chr1	151286742	Missense_Mutation	novel	E151K	0.31
SKCM	chr1	151286733	Missense_Mutation	NA	T148S	0.56
STAD	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.3
STAD	chr1	151290836	Missense_Mutation	NA	Y1114C	0.07
STAD	chr1	151289512	Frame_Shift_Del	novel	*R871Gfs29**	0.48
STAD	chr1	151287017	Silent	NA	S242S	0.11
STAD	chr1	151291217	3'UTR	novel		0.45
STAD	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.34
STAD	chr1	151290186	Missense_Mutation	NA	R1010H	0.3
STAD	chr1	151291170	Silent	rs137887486	A1225A	0.31
STAD	chr1	151288690	Missense_Mutation	rs373597091	R760C	0.55
STAD	chr1	151287677	Silent	NA	G462G	0.25
STAD	chr1	151287954	Missense_Mutation	rs375924931	R555W	0.57
STAD	chr1	151286436	Missense_Mutation	novel	S49R	0.11
STAD	chr1	151287660	Missense_Mutation	novel	G457W	0.21
STAD	chr1	151287952	Missense_Mutation	novel	R554H	0.39
STAD	chr1	151288690	Missense_Mutation	rs373597091	R760C	0.25
STAD	chr1	151290774	Silent	rs201368023	T1093T	0.26
STAD	chr1	151287650	Silent	rs376488322	D453D	0.18
STAD	chr1	151290452	Missense_Mutation	rs199981013	R1033H	0.44
STAD	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.1
STAD	chr1	151289393	Silent	rs751824217	C829C	0.15
STAD	chr1	151286982	Frame_Shift_Del	novel	*Q232Rfs3**	0.16
STAD	chr1	151286732	Silent	NA	G147G	0.12
STAD	chr1	151287515	Silent	NA	N408N	0.48
STAD	chr1	151287447	Missense_Mutation	NA	V386L	0.14
THCA	chr1	151290975	Missense_Mutation	novel	K1160N	0.22
THYM	chr1	151281678	5'Flank	novel		0.22
THYM	chr1	151288685	Frame_Shift_Del	novel	*R760Pfs99**	0.32
THYM	chr1	151291739	3'UTR	novel		0.21
UCEC	chr1	151287040	Missense_Mutation	novel	A250D	0.16
UCEC	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.24
UCEC	chr1	151289511	Frame_Shift_Ins	novel	*R871Kfs34**	0.46
UCEC	chr1	151287157	Missense_Mutation	NA	D289A	0.43
UCEC	chr1	151288039	Missense_Mutation	rs751766903	R583H	0.18
UCEC	chr1	151288317	Missense_Mutation	novel	L676M	0.32
UCEC	chr1	151287969	Missense_Mutation	NA	E560K	0.23
UCEC	chr1	151288587	Silent	novel	R725R	0.32
UCEC	chr1	151290899	Missense_Mutation	novel	Q1135R	0.27
UCEC	chr1	151286356	Missense_Mutation	novel	D22V	0.18
UCEC	chr1	151282035	5'Flank	novel		0.4
UCEC	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.49
UCEC	chr1	151288574	Missense_Mutation	novel	S721N	0.08
UCEC	chr1	151288359	Missense_Mutation	novel	A690S	0.26
UCEC	chr1	151289877	Missense_Mutation	novel	R945Q	0.49
UCEC	chr1	151286617	Missense_Mutation	novel	A109G	0.49
UCEC	chr1	151288098	Missense_Mutation	rs768167102	A603S	0.26
UCEC	chr1	151286359	Missense_Mutation	novel	A23V	0.37
UCEC	chr1	151288352	Silent	novel	G687G	0.44
UCEC	chr1	151290871	Missense_Mutation	novel	M1126L	0.39
UCEC	chr1	151287017	Silent	NA	S242S	0.19
UCEC	chr1	151288038	Missense_Mutation	rs780005793	R583C	0.35
UCEC	chr1	151289393	Silent	rs751824217	C829C	0.25
UCEC	chr1	151290891	Silent	NA	D1132D	0.26
UCEC	chr1	151287218	Silent	rs146975201	A309A	0.45
UCEC	chr1	151289451	Missense_Mutation	novel	H849Y	0.91
UCEC	chr1	151289992	Silent	NA	K983K	0.33
UCEC	chr1	151289977	Silent	rs150185392	Y978Y	0.22
UCEC	chr1	151286982	Missense_Mutation	novel	P231T	0.25
UCEC	chr1	151287608	Missense_Mutation	novel	K439N	0.27
UCEC	chr1	151287654	Missense_Mutation	rs144174264	R455W	0.29
UCEC	chr1	151287748	Missense_Mutation	rs762513980	G486D	0.34
UCEC	chr1	151290733	Missense_Mutation	rs148677920	R1080C	0.3
UCEC	chr1	151287495	Missense_Mutation	novel	P402S	0.14
UCEC	chr1	151286565	Missense_Mutation	novel	P92S	0.51
UCEC	chr1	151286818	Missense_Mutation	rs61739618	P176L	0.49
UCEC	chr1	151287822	Missense_Mutation	novel	L511F	0.5
UCEC	chr1	151287990	Missense_Mutation	rs775148649	A567T	0.41
UCEC	chr1	151288320	Missense_Mutation	novel	E677K	0.4
UCEC	chr1	151287654	Missense_Mutation	rs144174264	R455W	0.46
UCEC	chr1	151280055	5'Flank	novel		0.5
UCEC	chr1	151286306	Missense_Mutation	novel	K5N	0.43
UCEC	chr1	151286867	Silent	rs760348310	P192P	0.31
UCEC	chr1	151287451	Missense_Mutation	novel	S387N	0.1
UCEC	chr1	151282079	5'Flank	novel		0.18
UCEC	chr1	151286819	Silent	NA	P176P	0.51
UCEC	chr1	151291897	3'UTR	novel		0.38
UCEC	chr1	151288694	Missense_Mutation	rs764664257	R761H	0.39
UCEC	chr1	151281948	5'Flank	novel		0.29
UCEC	chr1	151287862	Missense_Mutation	novel	A524D	0.09
UCEC	chr1	151281622	5'Flank	novel		0.33
UCEC	chr1	151289852	Frame_Shift_Del	NA	*R939Vfs10**	0.41
UCEC	chr1	151286656	Missense_Mutation	rs771476616	R122Q	0.29
UCEC	chr1	151290127	Silent	novel	V990V	0.14
UCEC	chr1	151290530	Missense_Mutation	novel	G1059D	0.6
UCEC	chr1	151290765	Silent	rs777152065	P1090P	0.39
UCEC	chr1	151287308	Silent	rs141982116	C339C	0.66
UCEC	chr1	151287289	Missense_Mutation	NA	K333T	0.27
UCEC	chr1	151288603	Frame_Shift_Del	NA	*H733Mfs30**	0.23
UCEC	chr1	151280088	5'Flank	novel		0.34
UCEC	chr1	151286293	Translation_Start_Site	NA	M1?	0.33
UCEC	chr1	151287835	Missense_Mutation	novel	R515M	0.23
UCEC	chr1	151290457	Missense_Mutation	novel	F1035V	0.24
UCEC	chr1	151290773	Missense_Mutation	rs780774453	T1093M	0.25
UCEC	chr1	151286606	Silent	rs202243324	D105D	0.33
UCEC	chr1	151290995	Missense_Mutation	novel	A1167V	0.08
UCEC	chr1	151286983	Missense_Mutation	novel	P231L	0.09
UCEC	chr1	151286787	Missense_Mutation	novel	F166L	0.26
UCEC	chr1	151288542	Silent	novel	C710C	0.35
UCEC	chr1	151288662	Silent	novel	H750H	0.15
UCEC	chr1	151289804	Missense_Mutation	novel	E921K	0.17
UCEC	chr1	151286848	Missense_Mutation	rs770670817	R186Q	0.38
UCEC	chr1	151289512	Frame_Shift_Del	novel	*R871Gfs29**	0.24
UCEC	chr1	151288376	Silent	rs370819029	L695L	0.35
UCEC	chr1	151289402	Silent	rs146722973	C832C	0.24
UCEC	chr1	151286724	Missense_Mutation	novel	S145G	0.16
UCEC	chr1	151288304	Silent	rs376638678	T671T	0.31
UCEC	chr1	151286498	Silent	NA	A69A	0.24
UCEC	chr1	151286867	Silent	rs760348310	P192P	0.19
UCEC	chr1	151289726	Frame_Shift_Del	novel	*G896Vfs4**	0.43
UCEC	chr1	151281551	5'Flank	novel		0.41
UCEC	chr1	151287458	Missense_Mutation	novel	Q389H	0.29
UCEC	chr1	151287992	Silent	novel	A567A	0.23
UCS	chr1	151289393	Silent	rs751824217	C829C	0.42

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	AMP	0.1444	0.11282
CESC	AMP	0.4814	3.2002e-05
DLBC	DEL	0.0208	0.0017831
ESCA	AMP	0.4022	0.0022446
KIRC	AMP	0.0928	0.059566
LUSC	AMP	0.4311	1.6618e-06
PAAD	AMP	0.2174	0.085665
PCPG	AMP	0.1481	0.00029562
READ	AMP	0.2667	0.025154
SARC	AMP	0.3424	4.3422e-08
SKCM	AMP	0.4877	9.6912e-06
TGCT	AMP	0.34	0.088103

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00048	Kaplan-Meier Survival Analysis
ACC	0.003	Kaplan-Meier Survival Analysis
SKCM	0.03	Kaplan-Meier Survival Analysis
ESCA	0.046	Kaplan-Meier Survival Analysis
KIRP	0.042	Kaplan-Meier Survival Analysis
LAML	0.047	Kaplan-Meier Survival Analysis
UCEC	0.01	Kaplan-Meier Survival Analysis
LIHC	0.02	Kaplan-Meier Survival Analysis
LGG	0.031	Kaplan-Meier Survival Analysis
UVM	0.00089	Kaplan-Meier Survival Analysis