EuRBPDB

Description

Ensembl ID: ENSG00000143442 (Gene tree)
Gene ID: 23126
Gene Symbol: POGZ
Alias: KIAA0461|ZNF635m|ZNF280E
Full Name: pogo transposable element derived with ZNF domain
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 56,742 bases
Position: chr1:151,402,724-151,459,465
Accession: 18801
RBP type: non-canonical RBP
Summary: The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000491586	POGZ-213	4130	-	ENSP00000418408	1366 (aa)	-	Q7Z3K3
ENST00000531094	POGZ-218	4415	-	ENSP00000431259	1348 (aa)	-	Q7Z3K3
ENST00000467287	POGZ-209	649	-	-	- (aa)	-	-
ENST00000439756	POGZ-206	199	-	ENSP00000390156	8 (aa)	-	A0A0G2JHK5
ENST00000594456	POGZ-221	561	-	ENSP00000472860	109 (aa)	-	M0R2X2
ENST00000485040	POGZ-212	2741	-	-	- (aa)	-	-
ENST00000482678	POGZ-211	568	-	-	- (aa)	-	-
ENST00000497787	POGZ-216	490	-	-	- (aa)	-	-
ENST00000441516	POGZ-207	526	-	ENSP00000403955	60 (aa)	-	H7C238
ENST00000492528	POGZ-214	508	-	-	- (aa)	-	-
ENST00000358476	POGZ-202	6459	-	-	- (aa)	-	-
ENST00000476128	POGZ-210	397	-	-	- (aa)	-	-
ENST00000409503	POGZ-205	4813	XM_017000745	ENSP00000386836	1401 (aa)	XP_016856234	Q7Z3K3
ENST00000495253	POGZ-215	617	-	-	- (aa)	-	-
ENST00000450842	POGZ-208	489	-	ENSP00000395332	84 (aa)	-	A6PW30
ENST00000271715	POGZ-201	6626	XM_005244999	ENSP00000271715	1410 (aa)	XP_005245056	Q7Z3K3
ENST00000368863	POGZ-203	6054	-	ENSP00000357856	1315 (aa)	-	Q7Z3K3
ENST00000392723	POGZ-204	6152	XM_005245005	ENSP00000376484	1357 (aa)	XP_005245062	Q7Z3K3
ENST00000529669	POGZ-217	949	XM_024454306	ENSP00000432295	316 (aa)	XP_024310074	H0YCT3
ENST00000533461	POGZ-220	550	-	ENSP00000433934	151 (aa)	-	E9PIR8
ENST00000533351	POGZ-219	586	-	ENSP00000433637	139 (aa)	-	E9PJY9

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000143442	rs60354484	1	151435499	CT	Pulse pressure	30578418	[0.11-0.23] mmHg decrease	0.1669	EFO_0005763

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000143442	POGZ	100	98.013	ENSMUSG00000038902	Pogz	100	93.560	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000790	nuclear chromatin	20562864.	IDA	Component
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	21873635.	IBA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0005515	protein binding	10976766.19498464.20562864.20850016.25416956.26871637.27107012.27705803.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	20562864.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0007064	mitotic sister chromatid cohesion	20562864.	IMP	Process
GO:0010468	regulation of gene expression	21873635.	IBA	Process
GO:0035097	histone methyltransferase complex	21873635.	IBA	Component
GO:0046872	metal ion binding	-	IEA	Function
GO:0051301	cell division	-	IEA	Process
GO:0051382	kinetochore assembly	20562864.	IMP	Process