EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000143545 (Gene tree)
Gene ID: 5872
Gene Symbol: RAB13
Alias: -
Full Name: RAB13, member RAS oncogene family
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 4,761 bases
Position: chr1:153,981,617-153,986,377
Accession: 9762
RBP type: canonical RBP
Summary: This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000357564	MMR_HSR1	PF01926.23	0.0005	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000495720	RAB13-204	868	-	-	- (aa)	-	-
ENST00000462680	RAB13-202	2123	-	-	- (aa)	-	-
ENST00000614713	RAB13-205	1353	XM_017001959	ENSP00000480103	122 (aa)	XP_016857448	A0A087WWB9
ENST00000368575	RAB13-201	1176	-	ENSP00000357564	203 (aa)	-	P51153
ENST00000484297	RAB13-203	643	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000143545's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04530	Tight junction	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000143545's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000143545	RAB13	99	75.124	ENSACIG00000008584	rab13	97	75.124	Amphilophus_citrinellus
ENSG00000143545	RAB13	100	98.522	ENSANAG00000030247	-	100	98.522	Aotus_nancymaae
ENSG00000143545	RAB13	99	78.713	ENSAMXG00000030712	rab13	99	78.713	Astyanax_mexicanus
ENSG00000143545	RAB13	100	98.030	ENSBTAG00000017604	RAB13	100	98.030	Bos_taurus
ENSG00000143545	RAB13	80	47.239	WBGene00019317	K02E10.1	75	47.239	Caenorhabditis_elegans
ENSG00000143545	RAB13	100	98.030	ENSCJAG00000009933	-	100	98.030	Callithrix_jacchus
ENSG00000143545	RAB13	100	97.537	ENSCHIG00000022271	-	100	97.537	Capra_hircus
ENSG00000143545	RAB13	99	91.089	ENSCPOG00000011491	-	99	91.089	Cavia_porcellus
ENSG00000143545	RAB13	100	99.507	ENSCCAG00000028502	-	100	99.507	Cebus_capucinus
ENSG00000143545	RAB13	100	100.000	ENSCATG00000041779	-	100	100.000	Cercocebus_atys
ENSG00000143545	RAB13	100	91.133	ENSCLAG00000006603	-	100	91.133	Chinchilla_lanigera
ENSG00000143545	RAB13	100	100.000	ENSCANG00000036573	-	100	100.000	Colobus_angolensis_palliatus
ENSG00000143545	RAB13	100	95.567	ENSCGRG00001021505	Rab13	100	95.567	Cricetulus_griseus_chok1gshd
ENSG00000143545	RAB13	100	95.567	ENSCGRG00000012126	Rab13	100	95.567	Cricetulus_griseus_crigri
ENSG00000143545	RAB13	99	75.980	ENSCSEG00000002358	rab13	99	75.980	Cynoglossus_semilaevis
ENSG00000143545	RAB13	99	78.218	ENSDARG00000034771	rab13	99	78.218	Danio_rerio
ENSG00000143545	RAB13	100	94.581	ENSDORG00000001591	Rab13	100	94.581	Dipodomys_ordii
ENSG00000143545	RAB13	100	98.522	ENSEASG00005000683	-	100	98.522	Equus_asinus_asinus
ENSG00000143545	RAB13	100	98.522	ENSECAG00000016551	RAB13	100	98.522	Equus_caballus
ENSG00000143545	RAB13	99	90.099	ENSEEUG00000001233	-	99	90.099	Erinaceus_europaeus
ENSG00000143545	RAB13	99	76.733	ENSELUG00000012801	rab13	99	76.733	Esox_lucius
ENSG00000143545	RAB13	100	92.118	ENSFCAG00000045269	-	100	92.118	Felis_catus
ENSG00000143545	RAB13	65	96.970	ENSFDAG00000014469	-	100	96.970	Fukomys_damarensis
ENSG00000143545	RAB13	99	75.743	ENSFHEG00000021221	rab13	95	85.549	Fundulus_heteroclitus
ENSG00000143545	RAB13	99	75.248	ENSGACG00000011925	rab13	99	75.248	Gasterosteus_aculeatus
ENSG00000143545	RAB13	85	90.751	ENSGAGG00000000742	-	99	81.281	Gopherus_agassizii
ENSG00000143545	RAB13	100	100.000	ENSGGOG00000023693	RAB13	100	100.000	Gorilla_gorilla
ENSG00000143545	RAB13	100	90.148	ENSHGLG00000008749	RAB13	100	90.148	Heterocephalus_glaber_female
ENSG00000143545	RAB13	100	90.148	ENSHGLG00100013608	RAB13	100	90.148	Heterocephalus_glaber_male
ENSG00000143545	RAB13	99	73.762	ENSHCOG00000007440	rab13	95	86.127	Hippocampus_comes
ENSG00000143545	RAB13	99	77.000	ENSIPUG00000003199	rab13	99	77.000	Ictalurus_punctatus
ENSG00000143545	RAB13	100	97.044	ENSSTOG00000011222	-	100	97.044	Ictidomys_tridecemlineatus
ENSG00000143545	RAB13	100	92.118	ENSJJAG00000010575	Rab13	100	92.118	Jaculus_jaculus
ENSG00000143545	RAB13	99	75.500	ENSKMAG00000001908	rab13	99	75.500	Kryptolebias_marmoratus
ENSG00000143545	RAB13	99	77.000	ENSLBEG00000026779	rab13	99	77.000	Labrus_bergylta
ENSG00000143545	RAB13	85	77.907	ENSLACG00000008103	-	97	77.907	Latimeria_chalumnae
ENSG00000143545	RAB13	100	100.000	ENSMFAG00000041018	RAB13	100	100.000	Macaca_fascicularis
ENSG00000143545	RAB13	100	100.000	ENSMNEG00000028951	-	100	100.000	Macaca_nemestrina
ENSG00000143545	RAB13	100	100.000	ENSMLEG00000042247	-	100	100.000	Mandrillus_leucophaeus
ENSG00000143545	RAB13	99	75.248	ENSMAMG00000014602	rab13	99	75.248	Mastacembelus_armatus
ENSG00000143545	RAB13	100	94.581	ENSMAUG00000015713	Rab13	100	94.581	Mesocricetus_auratus
ENSG00000143545	RAB13	100	97.044	ENSMICG00000010340	-	100	97.044	Microcebus_murinus
ENSG00000143545	RAB13	100	95.567	ENSMOCG00000021448	Rab13	100	95.567	Microtus_ochrogaster
ENSG00000143545	RAB13	99	92.574	ENSMODG00000017295	-	84	92.574	Monodelphis_domestica
ENSG00000143545	RAB13	100	92.611	MGP_CAROLIEiJ_G0025227	Rab13	100	92.611	Mus_caroli
ENSG00000143545	RAB13	100	91.626	ENSMUSG00000027935	Rab13	100	91.626	Mus_musculus
ENSG00000143545	RAB13	99	92.079	MGP_PahariEiJ_G0026671	Rab13	99	92.079	Mus_pahari
ENSG00000143545	RAB13	100	95.567	ENSNGAG00000010309	Rab13	100	95.567	Nannospalax_galili
ENSG00000143545	RAB13	99	75.248	ENSNBRG00000004124	rab13	99	75.248	Neolamprologus_brichardi
ENSG00000143545	RAB13	100	100.000	ENSNLEG00000028944	-	100	100.000	Nomascus_leucogenys
ENSG00000143545	RAB13	100	92.157	ENSMEUG00000009667	-	100	92.157	Notamacropus_eugenii
ENSG00000143545	RAB13	100	89.655	ENSODEG00000010443	-	100	89.655	Octodon_degus
ENSG00000143545	RAB13	63	97.638	ENSODEG00000012634	-	100	97.638	Octodon_degus
ENSG00000143545	RAB13	99	75.743	ENSONIG00000006340	rab13	99	75.743	Oreochromis_niloticus
ENSG00000143545	RAB13	88	96.067	ENSOCUG00000006286	-	100	96.067	Oryctolagus_cuniculus
ENSG00000143545	RAB13	99	76.238	ENSOMEG00000008210	rab13	99	76.238	Oryzias_melastigma
ENSG00000143545	RAB13	99	94.059	ENSOGAG00000016969	-	99	94.059	Otolemur_garnettii
ENSG00000143545	RAB13	100	100.000	ENSPPAG00000028435	-	100	100.000	Pan_paniscus
ENSG00000143545	RAB13	100	92.118	ENSPPRG00000008865	-	100	92.118	Panthera_pardus
ENSG00000143545	RAB13	100	100.000	ENSPTRG00000001370	RAB13	100	100.000	Pan_troglodytes
ENSG00000143545	RAB13	100	100.000	ENSPANG00000004479	-	100	100.000	Papio_anubis
ENSG00000143545	RAB13	99	75.743	ENSPMGG00000007680	rab13	99	75.743	Periophthalmus_magnuspinnatus
ENSG00000143545	RAB13	53	97.222	ENSPEMG00000017353	-	81	97.222	Peromyscus_maniculatus_bairdii
ENSG00000143545	RAB13	100	92.647	ENSPCIG00000029350	-	100	92.647	Phascolarctos_cinereus
ENSG00000143545	RAB13	95	74.112	ENSPLAG00000005832	RAB13	93	83.815	Poecilia_latipinna
ENSG00000143545	RAB13	90	80.328	ENSPREG00000017567	rab13	99	74.257	Poecilia_reticulata
ENSG00000143545	RAB13	100	100.000	ENSPPYG00000000790	-	100	100.000	Pongo_abelii
ENSG00000143545	RAB13	100	98.030	ENSPCOG00000012189	-	100	98.030	Propithecus_coquereli
ENSG00000143545	RAB13	100	95.074	ENSPVAG00000011095	-	100	95.074	Pteropus_vampyrus
ENSG00000143545	RAB13	85	86.127	ENSPNAG00000004189	rab13	92	86.127	Pygocentrus_nattereri
ENSG00000143545	RAB13	100	92.611	ENSRNOG00000016733	Rab13	100	92.611	Rattus_norvegicus
ENSG00000143545	RAB13	100	99.507	ENSRBIG00000008552	-	100	99.507	Rhinopithecus_bieti
ENSG00000143545	RAB13	100	99.507	ENSRROG00000036885	-	100	99.507	Rhinopithecus_roxellana
ENSG00000143545	RAB13	100	99.015	ENSSBOG00000020342	-	100	99.015	Saimiri_boliviensis_boliviensis
ENSG00000143545	RAB13	100	91.667	ENSSHAG00000011866	-	100	91.667	Sarcophilus_harrisii
ENSG00000143545	RAB13	100	98.522	ENSSSCG00000006564	-	100	98.522	Sus_scrofa
ENSG00000143545	RAB13	99	76.733	ENSTRUG00000024177	rab13	99	76.733	Takifugu_rubripes
ENSG00000143545	RAB13	100	97.044	ENSTBEG00000012734	-	100	97.044	Tupaia_belangeri
ENSG00000143545	RAB13	100	99.507	ENSTTRG00000011183	-	100	99.507	Tursiops_truncatus
ENSG00000143545	RAB13	85	78.846	ENSXETG00000020729	rab13	99	78.882	Xenopus_tropicalis
ENSG00000143545	RAB13	85	82.659	ENSXCOG00000019533	rab13	93	82.659	Xiphophorus_couchianus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0005515	protein binding	9712853.16525024.18332111.20008558.21795389.23772379.	IPI	Function
GO:0005525	GTP binding	20937701.	IDA	Function
GO:0005794	Golgi apparatus	18779367.	IDA	Component
GO:0005802	trans-Golgi network	18779367.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	15528189.18779367.	IDA	Component
GO:0005923	bicellular tight junction	8294494.12058051.	IDA	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0010737	protein kinase A signaling	15096524.	IMP	Process
GO:0016197	endosomal transport	18779367.	IMP	Process
GO:0016328	lateral plasma membrane	12058051.	IDA	Component
GO:0030027	lamellipodium	-	ISS	Component
GO:0030054	cell junction	-	TAS	Component
GO:0030139	endocytic vesicle	15528189.	IDA	Component
GO:0030659	cytoplasmic vesicle membrane	-	IEA	Component
GO:0030866	cortical actin cytoskeleton organization	-	ISS	Process
GO:0031175	neuron projection development	20008558.	IMP	Process
GO:0031410	cytoplasmic vesicle	8294494.	IDA	Component
GO:0032456	endocytic recycling	15528189.	IMP	Process
GO:0032482	Rab protein signal transduction	21873635.	IBA	Process
GO:0032593	insulin-responsive compartment	-	ISS	Component
GO:0032869	cellular response to insulin stimulus	-	ISS	Process
GO:0035767	endothelial cell chemotaxis	-	ISS	Process
GO:0043005	neuron projection	20008558.	IDA	Component
GO:0043687	post-translational protein modification	-	TAS	Process
GO:0044795	trans-Golgi network to recycling endosome transport	-	ISS	Process
GO:0055037	recycling endosome	18779367.	IDA	Component
GO:0055038	recycling endosome membrane	-	IEA	Component
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:0070830	bicellular tight junction assembly	12058051.15096524.	IMP	Process
GO:0072659	protein localization to plasma membrane	15096524.	IMP	Process
GO:0097368	establishment of Sertoli cell barrier	-	ISS	Process