EuRBPDB

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  • Description
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000143569 (Gene tree)
Gene ID
9898
Gene Symbol
UBAP2L
Alias
NICE-4|KIAA0144
Full Name
ubiquitin associated protein 2 like
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
51,560 bases
Position
chr1:154,219,951-154,271,510
Accession
29877
RBP type
non-canonical RBP
Summary
(Ubiquitin Associated Protein 2 Like) is a Protein Coding gene. An important paralog of this gene is UBAP2.
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
16212419Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC).J Proteome Res2005 Sep-OctAmanchy R-
18698806Identification of c-Src tyrosine kinase substrates using mass spectrometry and peptide microarrays.J Proteome Res2008 SepAmanchy Rdoi: 10.1021/pr800198w
11230159Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library.Genome Res2001 MarMarenholz I-
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000428931UBAP2L-2073988XM_005245658ENSP000003894451087 (aa)XP_005245715Q14157
ENST00000343815UBAP2L-2023411XM_005245673ENSP00000345308983 (aa)XP_005245730Q14157
ENST00000489076UBAP2L-217850--- (aa)--
ENST00000456325UBAP2L-211812-ENSP00000415310234 (aa)-Q5VU80
ENST00000475373UBAP2L-214838--- (aa)--
ENST00000433615UBAP2L-2081789-ENSP00000407672399 (aa)-H7C2T8
ENST00000412596UBAP2L-205980-ENSP00000389052280 (aa)-Q5VU78
ENST00000465855UBAP2L-212684--- (aa)--
ENST00000495676UBAP2L-219867--- (aa)--
ENST00000271877UBAP2L-2013997XM_005245668ENSP000002718771079 (aa)XP_005245725F8W726
ENST00000466173UBAP2L-213804--- (aa)--
ENST00000361546UBAP2L-2033864XM_017002972ENSP000003553431087 (aa)XP_016858461Q14157
ENST00000441890UBAP2L-210678-ENSP00000399920182 (aa)-Q5VU81
ENST00000493867UBAP2L-218677--- (aa)--
ENST00000428595UBAP2L-2061419-ENSP00000398609383 (aa)-H0Y5H6
ENST00000484819UBAP2L-2161056--- (aa)--
ENST00000484696UBAP2L-215611--- (aa)--
ENST00000613315UBAP2L-2203451-ENSP00000478447976 (aa)-Q14157
ENST00000368504UBAP2L-2041120-ENSP00000357490350 (aa)-Q5VU77
ENST00000437652UBAP2L-209911-ENSP00000389717265 (aa)-Q5VU79
Gene Model
Click here to download ENSG00000143569's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000143569Platelet Function Tests9.5300000E-006-
ENSG00000143569Forced Expiratory Volume1.6330000E-00524983941
ENSG00000143569Forced Expiratory Volume1.4800000E-00524983941
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000143569rs120279991154233882CSmoking initiation (ever regular vs never regular) (MTAG)30643251[0.0087-0.0152] unit decrease0.011901EFO_0006527
ENSG00000143569rs120279991154233882CSmoking initiation (ever regular vs never regular)30643251[0.017-0.032] unit decrease0.024358766EFO_0006527
ENSG00000143569rs66737521154246701CSmoking initiation30617275[0.019-0.035] unit decrease (replication)0.027EFO_0005670
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000143569's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000143569UBAP2L9648.837ENSDARG00000060065ubap2b8256.923Danio_rerio
ENSG00000143569UBAP2L9856.216ENSG00000137073UBAP29559.143Homo_sapiens
ENSG00000143569UBAP2L10099.451ENSMUSG00000042520Ubap2l100100.000Mus_musculus
ENSG00000143569UBAP2L9850.671ENSMUSG00000028433Ubap29853.901Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0005515protein binding19945174.25185265.IPIFunction
GO:0005634nucleus21873635.IBAComponent
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex18838386.IDAComponent
GO:0005737cytoplasm21873635.IBAComponent
GO:0007339binding of sperm to zona pellucida19945174.IMPProcess
GO:0031519PcG protein complex25185265.IDAComponent
GO:0061484hematopoietic stem cell homeostasis21873635.IBAProcess
GO:0061484hematopoietic stem cell homeostasis25185265.IGIProcess

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