EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000144028 (Gene tree)
Gene ID: 23020
Gene Symbol: SNRNP200
Alias: U5-200KD|HELIC2|KIAA0788|BRR2|ASCC3L1|RP33
Full Name: small nuclear ribonucleoprotein U5 subunit 200
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 31,234 bases
Position: chr2:96,274,336-96,305,569
Accession: 30859
RBP type: canonical RBP
Summary: Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000317123	ResIII	PF04851.15	2.7e-25	1	2
ENSP00000317123	ResIII	PF04851.15	2.7e-25	2	2
ENSP00000317123	DEAD	PF00270.29	1.7e-51	1	2
ENSP00000317123	DEAD	PF00270.29	1.7e-51	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
23704370	Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.	Science	2013 Jul 5	Mozaffari-Jovin S	doi: 10.1126/science.1237515
29490241	Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2.	Biophys J	2018 Feb 27	Wollenhaupt J	doi: 10.1016/j.bpj.2017.12.033.
22889230	Virus-producing cells determine the host protein profiles of HIV-1 virion cores.	Retrovirology	2012 Aug 13	Santos S	doi: 10.1186/1742-4690-9-65.
27072132	Retinitis Pigmentosa Mutations in Bad Response to Refrigeration 2 (Brr2) Impair ATPase and Helicase Activity.	J Biol Chem	2016 Jun 3	Ledoux S	doi: 10.1074/jbc.M115.710848
26968627	Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing.	RNA	2016 May	Mayerle M	doi: 10.1261/rna.055459.115
26637280	The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation.	Genes Dev	2015 Dec 15	Absmeier E	doi: 10.1101/gad.271528.115
26161500	A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing.	Elife	2015 Jul 10	Liu S	doi: 10.7554/eLife.07320.
28838205	A new role for FBP21 as regulator of Brr2 helicase activity.	Nucleic Acids Res	2017 Jul 27	Henning LM	doi: 10.1093/nar/gkx535.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000480615	SNRNP200-204	1646	-	-	- (aa)	-	-
ENST00000497539	SNRNP200-208	2666	-	-	- (aa)	-	-
ENST00000429650	SNRNP200-202	2637	-	ENSP00000387870	595 (aa)	-	B4E0P5
ENST00000480242	SNRNP200-203	3409	-	-	- (aa)	-	-
ENST00000480835	SNRNP200-205	540	-	-	- (aa)	-	-
ENST00000493271	SNRNP200-207	585	-	-	- (aa)	-	-
ENST00000484372	SNRNP200-206	581	-	-	- (aa)	-	-
ENST00000323853	SNRNP200-201	7165	-	ENSP00000317123	2136 (aa)	-	O75643

Gene Model

Click here to download ENSG00000144028's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03040	Spliceosome	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000144028	Platelet Function Tests	2.0446500E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000144028	rs772178	2	96297946	A	Diastolic blood pressure	27618452	[0.13-0.28] mm Hg decrease	0.208	EFO_0006336
ENSG00000144028	rs186291940	2	96280803	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000144028's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000144028	SNRNP200	84	47.189	ENSG00000112249	ASCC3	80	44.463

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000144028	SNRNP200	99	90.888	ENSAPOG00000010223	snrnp200	99	90.777	Acanthochromis_polyacanthus
ENSG00000144028	SNRNP200	100	99.860	ENSAMEG00000008996	SNRNP200	100	99.860	Ailuropoda_melanoleuca
ENSG00000144028	SNRNP200	97	90.257	ENSACIG00000001764	snrnp200	98	90.257	Amphilophus_citrinellus
ENSG00000144028	SNRNP200	99	90.794	ENSAOCG00000024593	snrnp200	100	90.043	Amphiprion_ocellaris
ENSG00000144028	SNRNP200	97	90.096	ENSAPEG00000012554	snrnp200	100	90.096	Amphiprion_percula
ENSG00000144028	SNRNP200	99	90.653	ENSATEG00000022522	snrnp200	99	90.543	Anabas_testudineus
ENSG00000144028	SNRNP200	99	97.690	ENSAPLG00000004313	SNRNP200	100	97.690	Anas_platyrhynchos
ENSG00000144028	SNRNP200	99	97.497	ENSACAG00000000434	SNRNP200	100	97.497	Anolis_carolinensis
ENSG00000144028	SNRNP200	99	99.659	ENSANAG00000036625	SNRNP200	100	95.849	Aotus_nancymaae
ENSG00000144028	SNRNP200	99	90.512	ENSACLG00000011188	snrnp200	99	90.403	Astatotilapia_calliptera
ENSG00000144028	SNRNP200	99	90.630	ENSAMXG00000005684	snrnp200	99	90.496	Astyanax_mexicanus
ENSG00000144028	SNRNP200	100	99.298	ENSBTAG00000000848	SNRNP200	100	99.298	Bos_taurus
ENSG00000144028	SNRNP200	100	99.953	ENSCJAG00000007514	SNRNP200	100	99.953	Callithrix_jacchus
ENSG00000144028	SNRNP200	100	99.067	ENSCAFG00020019979	SNRNP200	100	99.883	Canis_lupus_dingo
ENSG00000144028	SNRNP200	100	99.485	ENSCHIG00000020611	SNRNP200	100	99.485	Capra_hircus
ENSG00000144028	SNRNP200	100	99.906	ENSTSYG00000010467	SNRNP200	100	99.906	Carlito_syrichta
ENSG00000144028	SNRNP200	99	99.830	ENSCAPG00000017234	SNRNP200	99	99.436	Cavia_aperea
ENSG00000144028	SNRNP200	100	99.719	ENSCPOG00000006776	SNRNP200	100	99.719	Cavia_porcellus
ENSG00000144028	SNRNP200	100	99.953	ENSCCAG00000033962	SNRNP200	100	99.953	Cebus_capucinus
ENSG00000144028	SNRNP200	100	100.000	ENSCATG00000015790	SNRNP200	100	100.000	Cercocebus_atys
ENSG00000144028	SNRNP200	100	99.579	ENSCLAG00000004116	SNRNP200	100	99.579	Chinchilla_lanigera
ENSG00000144028	SNRNP200	100	99.953	ENSCSAG00000017369	SNRNP200	100	99.953	Chlorocebus_sabaeus
ENSG00000144028	SNRNP200	92	94.984	ENSCHOG00000012981	-	59	99.213	Choloepus_hoffmanni
ENSG00000144028	SNRNP200	100	97.756	ENSCPBG00000022571	SNRNP200	100	97.756	Chrysemys_picta_bellii
ENSG00000144028	SNRNP200	99	78.535	ENSCING00000005082	-	99	76.740	Ciona_intestinalis
ENSG00000144028	SNRNP200	99	99.830	ENSCANG00000033932	SNRNP200	100	99.950	Colobus_angolensis_palliatus
ENSG00000144028	SNRNP200	100	99.766	ENSCGRG00001022610	Snrnp200	100	99.766	Cricetulus_griseus_chok1gshd
ENSG00000144028	SNRNP200	100	99.205	ENSCGRG00000016472	Snrnp200	100	99.205	Cricetulus_griseus_crigri
ENSG00000144028	SNRNP200	100	89.888	ENSCSEG00000016399	snrnp200	100	89.888	Cynoglossus_semilaevis
ENSG00000144028	SNRNP200	97	89.850	ENSCVAG00000017631	snrnp200	99	85.627	Cyprinodon_variegatus
ENSG00000144028	SNRNP200	99	91.652	ENSDARG00000077536	snrnp200	99	90.356	Danio_rerio
ENSG00000144028	SNRNP200	100	98.361	ENSDNOG00000011227	SNRNP200	100	98.361	Dasypus_novemcinctus
ENSG00000144028	SNRNP200	99	99.489	ENSDORG00000005861	Snrnp200	100	97.148	Dipodomys_ordii
ENSG00000144028	SNRNP200	99	75.507	FBgn0263599	l(3)72Ab	99	74.209	Drosophila_melanogaster
ENSG00000144028	SNRNP200	96	98.847	ENSETEG00000000162	SNRNP200	74	99.742	Echinops_telfairi
ENSG00000144028	SNRNP200	83	81.256	ENSEBUG00000016524	snrnp200	95	81.256	Eptatretus_burgeri
ENSG00000144028	SNRNP200	100	98.741	ENSEASG00005001884	SNRNP200	100	98.741	Equus_asinus_asinus
ENSG00000144028	SNRNP200	100	99.860	ENSECAG00000019675	SNRNP200	100	99.860	Equus_caballus
ENSG00000144028	SNRNP200	98	98.632	ENSEEUG00000012178	SNRNP200	93	100.000	Erinaceus_europaeus
ENSG00000144028	SNRNP200	99	91.482	ENSELUG00000018948	snrnp200	99	90.730	Esox_lucius
ENSG00000144028	SNRNP200	100	99.906	ENSFCAG00000010699	SNRNP200	100	99.906	Felis_catus
ENSG00000144028	SNRNP200	99	94.208	ENSFALG00000001368	-	95	92.857	Ficedula_albicollis
ENSG00000144028	SNRNP200	100	99.625	ENSFDAG00000004683	SNRNP200	100	99.625	Fukomys_damarensis
ENSG00000144028	SNRNP200	99	89.608	ENSFHEG00000003786	snrnp200	99	87.781	Fundulus_heteroclitus
ENSG00000144028	SNRNP200	100	89.673	ENSGMOG00000004881	snrnp200	99	89.626	Gadus_morhua
ENSG00000144028	SNRNP200	99	89.608	ENSGAFG00000010807	snrnp200	99	88.015	Gambusia_affinis
ENSG00000144028	SNRNP200	100	90.005	ENSGACG00000011474	snrnp200	99	89.911	Gasterosteus_aculeatus
ENSG00000144028	SNRNP200	99	97.862	ENSGAGG00000016069	SNRNP200	99	97.686	Gopherus_agassizii
ENSG00000144028	SNRNP200	100	100.000	ENSGGOG00000005174	SNRNP200	100	100.000	Gorilla_gorilla
ENSG00000144028	SNRNP200	97	87.780	ENSHBUG00000011322	snrnp200	99	87.827	Haplochromis_burtoni
ENSG00000144028	SNRNP200	100	99.719	ENSHGLG00000006654	SNRNP200	100	99.719	Heterocephalus_glaber_female
ENSG00000144028	SNRNP200	100	99.719	ENSHGLG00100018594	SNRNP200	100	99.719	Heterocephalus_glaber_male
ENSG00000144028	SNRNP200	100	99.860	ENSSTOG00000016351	SNRNP200	100	99.860	Ictidomys_tridecemlineatus
ENSG00000144028	SNRNP200	100	99.672	ENSJJAG00000023659	Snrnp200	100	99.672	Jaculus_jaculus
ENSG00000144028	SNRNP200	99	90.460	ENSKMAG00000003665	snrnp200	99	87.541	Kryptolebias_marmoratus
ENSG00000144028	SNRNP200	100	90.262	ENSLBEG00000021585	snrnp200	99	90.262	Labrus_bergylta
ENSG00000144028	SNRNP200	99	93.867	ENSLACG00000000226	SNRNP200	99	94.722	Latimeria_chalumnae
ENSG00000144028	SNRNP200	100	92.182	ENSLOCG00000015198	snrnp200	99	92.182	Lepisosteus_oculatus
ENSG00000144028	SNRNP200	100	99.485	ENSLAFG00000015626	SNRNP200	100	99.485	Loxodonta_africana
ENSG00000144028	SNRNP200	100	99.953	ENSMFAG00000040174	SNRNP200	100	99.953	Macaca_fascicularis
ENSG00000144028	SNRNP200	100	99.953	ENSMMUG00000023261	SNRNP200	100	99.953	Macaca_mulatta
ENSG00000144028	SNRNP200	100	99.906	ENSMNEG00000032398	SNRNP200	100	99.906	Macaca_nemestrina
ENSG00000144028	SNRNP200	100	100.000	ENSMLEG00000019083	SNRNP200	100	100.000	Mandrillus_leucophaeus
ENSG00000144028	SNRNP200	100	90.220	ENSMAMG00000007851	snrnp200	99	90.173	Mastacembelus_armatus
ENSG00000144028	SNRNP200	97	87.780	ENSMZEG00005010787	snrnp200	99	87.827	Maylandia_zebra
ENSG00000144028	SNRNP200	97	97.242	ENSMGAG00000001831	SNRNP200	100	97.242	Meleagris_gallopavo
ENSG00000144028	SNRNP200	100	99.813	ENSMAUG00000011825	Snrnp200	100	99.813	Mesocricetus_auratus
ENSG00000144028	SNRNP200	100	99.860	ENSMICG00000004710	SNRNP200	100	99.860	Microcebus_murinus
ENSG00000144028	SNRNP200	99	99.830	ENSMOCG00000011814	Snrnp200	100	97.238	Microtus_ochrogaster
ENSG00000144028	SNRNP200	99	89.009	ENSMMOG00000014167	snrnp200	99	88.904	Mola_mola
ENSG00000144028	SNRNP200	100	98.970	ENSMODG00000008475	SNRNP200	100	98.970	Monodelphis_domestica
ENSG00000144028	SNRNP200	99	90.794	ENSMALG00000001973	snrnp200	99	90.684	Monopterus_albus
ENSG00000144028	SNRNP200	100	99.625	MGP_CAROLIEiJ_G0024250	Snrnp200	100	99.625	Mus_caroli
ENSG00000144028	SNRNP200	100	99.672	ENSMUSG00000003660	Snrnp200	100	99.672	Mus_musculus
ENSG00000144028	SNRNP200	100	99.719	MGP_PahariEiJ_G0025695	Snrnp200	100	99.719	Mus_pahari
ENSG00000144028	SNRNP200	100	99.672	MGP_SPRETEiJ_G0025170	Snrnp200	100	99.724	Mus_spretus
ENSG00000144028	SNRNP200	100	99.813	ENSMPUG00000008949	SNRNP200	100	99.813	Mustela_putorius_furo
ENSG00000144028	SNRNP200	100	95.552	ENSMLUG00000027511	-	100	95.552	Myotis_lucifugus
ENSG00000144028	SNRNP200	100	99.252	ENSMLUG00000010493	SNRNP200	100	99.252	Myotis_lucifugus
ENSG00000144028	SNRNP200	100	99.906	ENSNGAG00000021993	Snrnp200	100	99.906	Nannospalax_galili
ENSG00000144028	SNRNP200	92	91.236	ENSNBRG00000017960	snrnp200	98	90.319	Neolamprologus_brichardi
ENSG00000144028	SNRNP200	99	97.956	ENSNLEG00000000025	SNRNP200	100	95.593	Nomascus_leucogenys
ENSG00000144028	SNRNP200	100	100.000	ENSMEUG00000010532	SNRNP200	79	100.000	Notamacropus_eugenii
ENSG00000144028	SNRNP200	99	99.830	ENSOPRG00000015464	SNRNP200	100	95.974	Ochotona_princeps
ENSG00000144028	SNRNP200	100	99.579	ENSODEG00000008366	SNRNP200	100	99.579	Octodon_degus
ENSG00000144028	SNRNP200	99	90.512	ENSONIG00000010714	snrnp200	99	90.403	Oreochromis_niloticus
ENSG00000144028	SNRNP200	100	99.766	ENSOCUG00000009864	SNRNP200	100	99.766	Oryctolagus_cuniculus
ENSG00000144028	SNRNP200	100	90.309	ENSORLG00000012286	snrnp200	100	90.309	Oryzias_latipes
ENSG00000144028	SNRNP200	100	90.356	ENSORLG00020004648	snrnp200	100	90.356	Oryzias_latipes_hni
ENSG00000144028	SNRNP200	100	90.309	ENSORLG00015019114	snrnp200	100	90.339	Oryzias_latipes_hsok
ENSG00000144028	SNRNP200	99	90.559	ENSOMEG00000011834	snrnp200	99	90.449	Oryzias_melastigma
ENSG00000144028	SNRNP200	100	99.906	ENSOGAG00000006879	SNRNP200	100	99.906	Otolemur_garnettii
ENSG00000144028	SNRNP200	100	98.456	ENSOARG00000013949	SNRNP200	100	98.456	Ovis_aries
ENSG00000144028	SNRNP200	100	100.000	ENSPPAG00000041559	SNRNP200	100	100.000	Pan_paniscus
ENSG00000144028	SNRNP200	100	99.906	ENSPPRG00000004435	SNRNP200	100	99.906	Panthera_pardus
ENSG00000144028	SNRNP200	100	99.438	ENSPTIG00000006380	SNRNP200	100	99.438	Panthera_tigris_altaica
ENSG00000144028	SNRNP200	100	100.000	ENSPTRG00000012230	SNRNP200	100	100.000	Pan_troglodytes
ENSG00000144028	SNRNP200	100	99.953	ENSPANG00000006017	SNRNP200	100	99.953	Papio_anubis
ENSG00000144028	SNRNP200	100	91.105	ENSPKIG00000014762	snrnp200	99	91.105	Paramormyrops_kingsleyae
ENSG00000144028	SNRNP200	100	96.724	ENSPSIG00000008580	SNRNP200	100	96.724	Pelodiscus_sinensis
ENSG00000144028	SNRNP200	100	98.970	ENSPCIG00000023050	SNRNP200	100	98.970	Phascolarctos_cinereus
ENSG00000144028	SNRNP200	100	90.360	ENSPFOG00000015110	snrnp200	99	90.360	Poecilia_formosa
ENSG00000144028	SNRNP200	97	90.220	ENSPLAG00000006711	snrnp200	99	90.220	Poecilia_latipinna
ENSG00000144028	SNRNP200	97	90.165	ENSPMEG00000021166	snrnp200	99	90.165	Poecilia_mexicana
ENSG00000144028	SNRNP200	100	90.449	ENSPREG00000008875	snrnp200	99	90.449	Poecilia_reticulata
ENSG00000144028	SNRNP200	100	100.000	ENSPPYG00000012068	SNRNP200	100	100.000	Pongo_abelii
ENSG00000144028	SNRNP200	99	99.489	ENSPCAG00000008536	SNRNP200	89	98.718	Procavia_capensis
ENSG00000144028	SNRNP200	100	99.906	ENSPCOG00000024608	SNRNP200	100	99.906	Propithecus_coquereli
ENSG00000144028	SNRNP200	99	98.296	ENSPVAG00000005860	SNRNP200	93	100.000	Pteropus_vampyrus
ENSG00000144028	SNRNP200	99	88.870	ENSPNYG00000017476	snrnp200	99	85.994	Pundamilia_nyererei
ENSG00000144028	SNRNP200	99	90.801	ENSPNAG00000010998	snrnp200	99	86.096	Pygocentrus_nattereri
ENSG00000144028	SNRNP200	100	99.813	ENSRNOG00000012157	Snrnp200	100	99.813	Rattus_norvegicus
ENSG00000144028	SNRNP200	100	100.000	ENSRBIG00000044690	-	100	100.000	Rhinopithecus_bieti
ENSG00000144028	SNRNP200	100	100.000	ENSRROG00000037952	-	100	100.000	Rhinopithecus_roxellana
ENSG00000144028	SNRNP200	100	99.953	ENSSBOG00000035471	SNRNP200	100	99.953	Saimiri_boliviensis_boliviensis
ENSG00000144028	SNRNP200	99	98.637	ENSSHAG00000000758	SNRNP200	100	98.887	Sarcophilus_harrisii
ENSG00000144028	SNRNP200	99	92.334	ENSSFOG00015018826	snrnp200	99	91.526	Scleropages_formosus
ENSG00000144028	SNRNP200	99	90.465	ENSSMAG00000005463	snrnp200	99	90.356	Scophthalmus_maximus
ENSG00000144028	SNRNP200	99	90.747	ENSSDUG00000021410	snrnp200	99	90.637	Seriola_dumerili
ENSG00000144028	SNRNP200	99	90.700	ENSSLDG00000010884	snrnp200	99	90.590	Seriola_lalandi_dorsalis
ENSG00000144028	SNRNP200	96	99.438	ENSSARG00000010728	SNRNP200	96	99.196	Sorex_araneus
ENSG00000144028	SNRNP200	100	97.519	ENSSPUG00000003726	-	100	97.519	Sphenodon_punctatus
ENSG00000144028	SNRNP200	99	90.801	ENSSPAG00000001842	snrnp200	99	90.684	Stegastes_partitus
ENSG00000144028	SNRNP200	100	99.719	ENSSSCG00000008127	SNRNP200	100	99.719	Sus_scrofa
ENSG00000144028	SNRNP200	99	87.975	ENSTGUG00000014475	-	100	87.975	Taeniopygia_guttata
ENSG00000144028	SNRNP200	99	90.971	ENSTRUG00000001307	snrnp200	99	90.309	Takifugu_rubripes
ENSG00000144028	SNRNP200	100	85.925	ENSTNIG00000004320	snrnp200	100	85.925	Tetraodon_nigroviridis
ENSG00000144028	SNRNP200	82	100.000	ENSTBEG00000003329	-	67	100.000	Tupaia_belangeri
ENSG00000144028	SNRNP200	100	99.532	ENSTTRG00000004983	SNRNP200	100	99.532	Tursiops_truncatus
ENSG00000144028	SNRNP200	75	93.023	ENSUAMG00000008395	-	95	93.023	Ursus_americanus
ENSG00000144028	SNRNP200	100	99.906	ENSUMAG00000012385	SNRNP200	100	99.906	Ursus_maritimus
ENSG00000144028	SNRNP200	90	100.000	ENSVPAG00000006434	SNRNP200	69	100.000	Vicugna_pacos
ENSG00000144028	SNRNP200	100	99.673	ENSVVUG00000026247	SNRNP200	100	99.673	Vulpes_vulpes
ENSG00000144028	SNRNP200	100	94.343	ENSXETG00000001243	snrnp200	100	94.343	Xenopus_tropicalis
ENSG00000144028	SNRNP200	97	90.471	ENSXMAG00000002058	snrnp200	98	90.471	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000354	cis assembly of pre-catalytic spliceosome	9539711.	IC	Process
GO:0000388	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	11991638.	IC	Process
GO:0000398	mRNA splicing, via spliceosome	8670905.	IDA	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0001649	osteoblast differentiation	16210410.	HDA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0004004	ATP-dependent RNA helicase activity	21873635.	IBA	Function
GO:0004004	ATP-dependent RNA helicase activity	23045696.	IDA	Function
GO:0005515	protein binding	16730941.18951082.22365833.22720776.23793891.28838205.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	22720776.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005681	spliceosomal complex	21873635.	IBA	Component
GO:0005681	spliceosomal complex	8670905.	IDA	Component
GO:0005682	U5 snRNP	21873635.	IBA	Component
GO:0005682	U5 snRNP	9539711.	IDA	Component
GO:0008026	ATP-dependent helicase activity	21873635.	IBA	Function
GO:0008026	ATP-dependent helicase activity	9539711.	IDA	Function
GO:0016020	membrane	16210410.	HDA	Component
GO:0042802	identical protein binding	22365833.	IPI	Function
GO:0046540	U4/U6 x U5 tri-snRNP complex	21873635.	IBA	Component
GO:0046540	U4/U6 x U5 tri-snRNP complex	23793891.	IDA	Component
GO:0071013	catalytic step 2 spliceosome	21873635.	IBA	Component
GO:0071013	catalytic step 2 spliceosome	11991638.	IDA	Component
GO:0071014	post-mRNA release spliceosomal complex	21873635.	IBA	Component