EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000144045 (Gene tree)
Gene ID: 165545
Gene Symbol: DQX1
Alias: FLJ23757
Full Name: DEAQ-box RNA dependent ATPase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 8,206 bases
Position: chr2:74,518,131-74,526,336
Accession: 20410
RBP type: canonical RBP
Summary: (DEAQ-Box RNA Dependent ATPase 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ATP-dependent RNA helicase activity. An important paralog of this gene is DHX32.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000377523	HA2	PF04408.23	9.8e-18	1	1
ENSP00000384621	HA2	PF04408.23	9.8e-18	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000404568	DQX1-202	2689	XM_011532645	ENSP00000384621	717 (aa)	XP_011530947	Q8TE96
ENST00000495597	DQX1-207	589	-	-	- (aa)	-	-
ENST00000473508	DQX1-205	2136	-	-	- (aa)	-	-
ENST00000498552	DQX1-208	100	-	-	- (aa)	-	-
ENST00000483555	DQX1-206	832	-	-	- (aa)	-	-
ENST00000451518	DQX1-204	555	-	ENSP00000392969	119 (aa)	-	C9J0W1
ENST00000393951	DQX1-201	2540	-	ENSP00000377523	717 (aa)	-	Q8TE96
ENST00000418139	DQX1-203	1688	-	ENSP00000389196	132 (aa)	-	H7BZE3

Gene Model

Click here to download ENSG00000144045's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000144045	Platelet Function Tests	3.8226867E-006	-
ENSG00000144045	Platelet Function Tests	2.1828990E-006	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000144045's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000144045	DQX1	100	35.833	ENSG00000204560	DHX16	90	31.538
ENSG00000144045	DQX1	93	32.362	ENSG00000101452	DHX35	93	32.362
ENSG00000144045	DQX1	93	38.248	ENSG00000109606	DHX15	84	38.248
ENSG00000144045	DQX1	91	30.643	ENSG00000005100	DHX33	91	30.344
ENSG00000144045	DQX1	90	40.187	ENSG00000140829	DHX38	71	34.409
ENSG00000144045	DQX1	95	44.209	ENSG00000089876	DHX32	95	49.148
ENSG00000144045	DQX1	90	38.182	ENSG00000108406	DHX40	87	35.391
ENSG00000144045	DQX1	73	30.418	ENSG00000150990	DHX37	58	30.418
ENSG00000144045	DQX1	91	32.675	ENSG00000067596	DHX8	52	32.675

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000144045	DQX1	97	51.944	ENSAPOG00000005067	dqx1	91	51.719	Acanthochromis_polyacanthus
ENSG00000144045	DQX1	100	88.317	ENSAMEG00000017193	DQX1	100	88.317	Ailuropoda_melanoleuca
ENSG00000144045	DQX1	51	55.645	ENSACIG00000007128	-	95	55.645	Amphilophus_citrinellus
ENSG00000144045	DQX1	97	51.857	ENSAOCG00000020792	dqx1	91	51.635	Amphiprion_ocellaris
ENSG00000144045	DQX1	97	51.872	ENSAPEG00000011785	dqx1	91	51.648	Amphiprion_percula
ENSG00000144045	DQX1	98	48.708	ENSATEG00000009375	dqx1	94	48.708	Anabas_testudineus
ENSG00000144045	DQX1	86	60.160	ENSACAG00000004745	DQX1	94	60.160	Anolis_carolinensis
ENSG00000144045	DQX1	100	94.730	ENSANAG00000033980	DQX1	100	94.730	Aotus_nancymaae
ENSG00000144045	DQX1	97	51.377	ENSACLG00000006845	dqx1	91	51.377	Astatotilapia_calliptera
ENSG00000144045	DQX1	95	53.073	ENSAMXG00000009153	dqx1	91	53.073	Astyanax_mexicanus
ENSG00000144045	DQX1	100	86.092	ENSBTAG00000016609	DQX1	100	86.092	Bos_taurus
ENSG00000144045	DQX1	100	94.576	ENSCJAG00000017388	DQX1	100	94.576	Callithrix_jacchus
ENSG00000144045	DQX1	100	87.761	ENSCAFG00000008425	DQX1	100	87.761	Canis_familiaris
ENSG00000144045	DQX1	99	85.593	ENSCAFG00020014095	DQX1	99	85.160	Canis_lupus_dingo
ENSG00000144045	DQX1	100	86.787	ENSCHIG00000019357	DQX1	100	86.787	Capra_hircus
ENSG00000144045	DQX1	100	84.284	ENSTSYG00000001608	DQX1	100	84.284	Carlito_syrichta
ENSG00000144045	DQX1	93	77.928	ENSCAPG00000000387	DQX1	97	77.928	Cavia_aperea
ENSG00000144045	DQX1	100	87.204	ENSCPOG00000022849	DQX1	100	87.204	Cavia_porcellus
ENSG00000144045	DQX1	100	95.828	ENSCCAG00000031484	DQX1	100	95.828	Cebus_capucinus
ENSG00000144045	DQX1	100	97.350	ENSCATG00000037156	DQX1	100	97.350	Cercocebus_atys
ENSG00000144045	DQX1	100	88.039	ENSCLAG00000007521	DQX1	100	88.039	Chinchilla_lanigera
ENSG00000144045	DQX1	100	97.211	ENSCSAG00000015682	DQX1	100	97.211	Chlorocebus_sabaeus
ENSG00000144045	DQX1	94	63.188	ENSCPBG00000024467	DQX1	86	63.188	Chrysemys_picta_bellii
ENSG00000144045	DQX1	100	96.932	ENSCANG00000039725	DQX1	100	96.932	Colobus_angolensis_palliatus
ENSG00000144045	DQX1	99	85.112	ENSCGRG00001011093	Dqx1	99	85.112	Cricetulus_griseus_chok1gshd
ENSG00000144045	DQX1	99	85.112	ENSCGRG00000015486	Dqx1	99	85.112	Cricetulus_griseus_crigri
ENSG00000144045	DQX1	80	48.336	ENSCSEG00000018927	dqx1	96	48.336	Cynoglossus_semilaevis
ENSG00000144045	DQX1	97	50.067	ENSCVAG00000007365	dqx1	94	49.934	Cyprinodon_variegatus
ENSG00000144045	DQX1	100	84.979	ENSDNOG00000019907	DQX1	100	84.979	Dasypus_novemcinctus
ENSG00000144045	DQX1	100	87.917	ENSDORG00000013672	Dqx1	100	87.917	Dipodomys_ordii
ENSG00000144045	DQX1	99	81.356	ENSETEG00000011890	DQX1	100	84.385	Echinops_telfairi
ENSG00000144045	DQX1	98	45.526	ENSEBUG00000005072	DQX1	72	45.526	Eptatretus_burgeri
ENSG00000144045	DQX1	99	88.999	ENSEASG00005010654	DQX1	99	88.999	Equus_asinus_asinus
ENSG00000144045	DQX1	99	88.999	ENSECAG00000023896	DQX1	99	88.999	Equus_caballus
ENSG00000144045	DQX1	96	51.018	ENSELUG00000015619	dqx1	91	51.018	Esox_lucius
ENSG00000144045	DQX1	100	89.152	ENSFCAG00000028272	DQX1	100	89.152	Felis_catus
ENSG00000144045	DQX1	94	61.674	ENSFALG00000010921	DQX1	96	59.888	Ficedula_albicollis
ENSG00000144045	DQX1	100	88.595	ENSFDAG00000012179	DQX1	100	88.595	Fukomys_damarensis
ENSG00000144045	DQX1	97	49.930	ENSGMOG00000008923	dqx1	99	49.728	Gadus_morhua
ENSG00000144045	DQX1	98	60.306	ENSGALG00000033656	DQX1	97	59.972	Gallus_gallus
ENSG00000144045	DQX1	97	49.134	ENSGAFG00000008279	dqx1	96	48.695	Gambusia_affinis
ENSG00000144045	DQX1	97	50.413	ENSGACG00000018495	dqx1	98	50.136	Gasterosteus_aculeatus
ENSG00000144045	DQX1	100	100.000	ENSGGOG00000006307	DQX1	100	99.442	Gorilla_gorilla
ENSG00000144045	DQX1	97	51.377	ENSHBUG00000012890	dqx1	91	51.377	Haplochromis_burtoni
ENSG00000144045	DQX1	99	87.288	ENSHGLG00000011994	DQX1	99	80.559	Heterocephalus_glaber_female
ENSG00000144045	DQX1	99	87.288	ENSHGLG00100012005	DQX1	99	80.559	Heterocephalus_glaber_male
ENSG00000144045	DQX1	97	50.392	ENSHCOG00000002562	dqx1	94	50.392	Hippocampus_comes
ENSG00000144045	DQX1	97	52.797	ENSIPUG00000015152	DQX1	95	52.797	Ictalurus_punctatus
ENSG00000144045	DQX1	100	88.178	ENSSTOG00000026252	DQX1	100	88.178	Ictidomys_tridecemlineatus
ENSG00000144045	DQX1	99	86.779	ENSJJAG00000017070	Dqx1	99	86.779	Jaculus_jaculus
ENSG00000144045	DQX1	94	52.941	ENSKMAG00000002776	dqx1	89	53.058	Kryptolebias_marmoratus
ENSG00000144045	DQX1	97	50.954	ENSLBEG00000020503	dqx1	95	50.670	Labrus_bergylta
ENSG00000144045	DQX1	95	46.262	ENSLACG00000007417	-	95	45.135	Latimeria_chalumnae
ENSG00000144045	DQX1	90	48.148	ENSLOCG00000001140	dqx1	100	55.054	Lepisosteus_oculatus
ENSG00000144045	DQX1	99	88.128	ENSLAFG00000018370	DQX1	100	88.128	Loxodonta_africana
ENSG00000144045	DQX1	100	97.211	ENSMFAG00000001892	DQX1	100	97.211	Macaca_fascicularis
ENSG00000144045	DQX1	100	97.071	ENSMMUG00000002129	DQX1	100	97.071	Macaca_mulatta
ENSG00000144045	DQX1	100	97.350	ENSMNEG00000043354	DQX1	100	97.350	Macaca_nemestrina
ENSG00000144045	DQX1	100	97.350	ENSMLEG00000028743	DQX1	100	97.350	Mandrillus_leucophaeus
ENSG00000144045	DQX1	94	51.440	ENSMAMG00000022633	dqx1	94	50.344	Mastacembelus_armatus
ENSG00000144045	DQX1	97	51.377	ENSMZEG00005002422	dqx1	91	51.377	Maylandia_zebra
ENSG00000144045	DQX1	98	84.495	ENSMAUG00000022113	Dqx1	99	84.495	Mesocricetus_auratus
ENSG00000144045	DQX1	100	91.516	ENSMICG00000006232	DQX1	100	91.516	Microcebus_murinus
ENSG00000144045	DQX1	99	83.613	ENSMOCG00000017871	Dqx1	99	83.613	Microtus_ochrogaster
ENSG00000144045	DQX1	97	50.536	ENSMMOG00000003933	dqx1	94	50.265	Mola_mola
ENSG00000144045	DQX1	97	76.338	ENSMODG00000004879	DQX1	100	77.966	Monodelphis_domestica
ENSG00000144045	DQX1	94	50.822	ENSMALG00000015132	dqx1	90	50.403	Monopterus_albus
ENSG00000144045	DQX1	99	84.454	ENSMUSG00000009145	Dqx1	99	84.454	Mus_musculus
ENSG00000144045	DQX1	99	86.441	ENSNGAG00000022609	Dqx1	99	86.115	Nannospalax_galili
ENSG00000144045	DQX1	97	51.377	ENSNBRG00000004923	dqx1	91	51.377	Neolamprologus_brichardi
ENSG00000144045	DQX1	100	96.513	ENSNLEG00000000771	DQX1	100	96.513	Nomascus_leucogenys
ENSG00000144045	DQX1	99	72.034	ENSMEUG00000013231	DQX1	100	72.082	Notamacropus_eugenii
ENSG00000144045	DQX1	100	87.065	ENSODEG00000012521	DQX1	100	87.065	Octodon_degus
ENSG00000144045	DQX1	97	51.950	ENSONIG00000012572	dqx1	96	51.950	Oreochromis_niloticus
ENSG00000144045	DQX1	99	87.288	ENSOCUG00000015372	DQX1	100	82.749	Oryctolagus_cuniculus
ENSG00000144045	DQX1	94	51.909	ENSORLG00000014277	dqx1	92	51.163	Oryzias_latipes
ENSG00000144045	DQX1	94	51.841	ENSORLG00020004148	dqx1	92	51.096	Oryzias_latipes_hni
ENSG00000144045	DQX1	94	52.192	ENSORLG00015017580	dqx1	89	52.113	Oryzias_latipes_hsok
ENSG00000144045	DQX1	97	50.538	ENSOMEG00000015481	dqx1	95	50.469	Oryzias_melastigma
ENSG00000144045	DQX1	100	89.708	ENSOGAG00000001065	DQX1	100	89.708	Otolemur_garnettii
ENSG00000144045	DQX1	100	87.204	ENSOARG00000012775	DQX1	99	87.204	Ovis_aries
ENSG00000144045	DQX1	100	100.000	ENSPPAG00000034827	DQX1	100	96.585	Pan_paniscus
ENSG00000144045	DQX1	100	88.873	ENSPPRG00000007947	DQX1	100	88.873	Panthera_pardus
ENSG00000144045	DQX1	100	88.178	ENSPTIG00000016302	DQX1	100	88.178	Panthera_tigris_altaica
ENSG00000144045	DQX1	100	100.000	ENSPTRG00000012096	DQX1	100	99.582	Pan_troglodytes
ENSG00000144045	DQX1	100	97.211	ENSPANG00000014436	DQX1	100	97.211	Papio_anubis
ENSG00000144045	DQX1	96	56.835	ENSPKIG00000016273	dqx1	93	49.584	Paramormyrops_kingsleyae
ENSG00000144045	DQX1	100	85.160	ENSPEMG00000000695	Dqx1	100	85.160	Peromyscus_maniculatus_bairdii
ENSG00000144045	DQX1	89	46.226	ENSPMAG00000000247	dqx1	99	50.292	Petromyzon_marinus
ENSG00000144045	DQX1	99	77.731	ENSPCIG00000006057	DQX1	99	77.731	Phascolarctos_cinereus
ENSG00000144045	DQX1	97	50.203	ENSPFOG00000006654	dqx1	97	49.735	Poecilia_formosa
ENSG00000144045	DQX1	97	50.203	ENSPLAG00000019886	dqx1	97	49.735	Poecilia_latipinna
ENSG00000144045	DQX1	96	50.754	ENSPMEG00000004991	dqx1	88	50.269	Poecilia_mexicana
ENSG00000144045	DQX1	94	50.989	ENSPREG00000007179	dqx1	89	49.734	Poecilia_reticulata
ENSG00000144045	DQX1	100	100.000	ENSPPYG00000012268	DQX1	100	98.664	Pongo_abelii
ENSG00000144045	DQX1	84	85.839	ENSPCAG00000016943	DQX1	84	85.839	Procavia_capensis
ENSG00000144045	DQX1	100	91.377	ENSPCOG00000021586	DQX1	100	91.377	Propithecus_coquereli
ENSG00000144045	DQX1	100	87.344	ENSPVAG00000013964	DQX1	100	87.344	Pteropus_vampyrus
ENSG00000144045	DQX1	97	51.240	ENSPNYG00000003028	dqx1	91	51.240	Pundamilia_nyererei
ENSG00000144045	DQX1	96	53.138	ENSPNAG00000023120	dqx1	92	53.138	Pygocentrus_nattereri
ENSG00000144045	DQX1	99	84.712	ENSRNOG00000008062	Dqx1	99	84.712	Rattus_norvegicus
ENSG00000144045	DQX1	100	97.071	ENSRBIG00000041823	DQX1	100	97.071	Rhinopithecus_bieti
ENSG00000144045	DQX1	100	97.071	ENSRROG00000039342	DQX1	100	97.071	Rhinopithecus_roxellana
ENSG00000144045	DQX1	100	95.132	ENSSBOG00000028107	DQX1	100	95.132	Saimiri_boliviensis_boliviensis
ENSG00000144045	DQX1	99	77.560	ENSSHAG00000016833	DQX1	99	77.560	Sarcophilus_harrisii
ENSG00000144045	DQX1	95	50.354	ENSSFOG00015003817	dqx1	91	50.282	Scleropages_formosus
ENSG00000144045	DQX1	97	48.100	ENSSMAG00000010612	dqx1	94	48.114	Scophthalmus_maximus
ENSG00000144045	DQX1	94	50.548	ENSSDUG00000020759	dqx1	91	50.548	Seriola_dumerili
ENSG00000144045	DQX1	94	50.685	ENSSLDG00000022712	dqx1	91	50.685	Seriola_lalandi_dorsalis
ENSG00000144045	DQX1	98	51.715	ENSSPAG00000013343	dqx1	94	51.715	Stegastes_partitus
ENSG00000144045	DQX1	100	89.708	ENSSSCG00000022614	DQX1	100	89.708	Sus_scrofa
ENSG00000144045	DQX1	100	46.509	ENSTRUG00000012911	dqx1	100	51.554	Takifugu_rubripes
ENSG00000144045	DQX1	99	84.746	ENSTBEG00000010252	DQX1	100	87.978	Tupaia_belangeri
ENSG00000144045	DQX1	82	89.933	ENSTTRG00000012725	DQX1	82	89.933	Tursiops_truncatus
ENSG00000144045	DQX1	100	87.761	ENSUAMG00000021690	DQX1	100	87.761	Ursus_americanus
ENSG00000144045	DQX1	100	86.926	ENSUMAG00000001677	DQX1	100	86.926	Ursus_maritimus
ENSG00000144045	DQX1	50	92.199	ENSVPAG00000007907	-	50	92.199	Vicugna_pacos
ENSG00000144045	DQX1	100	88.039	ENSVVUG00000004178	DQX1	100	88.039	Vulpes_vulpes
ENSG00000144045	DQX1	97	49.933	ENSXMAG00000010692	dqx1	90	49.472	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0034459	ATP-dependent 3'-5' RNA helicase activity	21873635.	IBA	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr2	74519208	Missense_Mutation	novel	T610I	0.49
BLCA	chr2	74525011	Splice_Region	novel	L143L	0.35
BLCA	chr2	74519669	Missense_Mutation	novel	E565K	0.3
BLCA	chr2	74525091	Missense_Mutation	NA	D117N	0.16
BLCA	chr2	74522678	Nonsense_Mutation	NA	S466*	0.14	HA2
BLCA	chr2	74522758	Silent	novel	L439L	0.11
BLCA	chr2	74524199	Silent	novel	D180D	0.2
BLCA	chr2	74518431	3'UTR	novel		0.46
BRCA	chr2	74525070	Missense_Mutation	NA	G124C	0.39
BRCA	chr2	74523471	Missense_Mutation	NA	P295T	0.57
BRCA	chr2	74522766	Nonsense_Mutation	NA	E437*	0.18
CESC	chr2	74523432	Missense_Mutation	rs540562599	V308I	0.44
CESC	chr2	74524060	Missense_Mutation	NA	E227K	0.24
CESC	chr2	74522761	Silent	novel	A438A	0.32
CESC	chr2	74519206	Nonsense_Mutation	NA	G611*	0.38
COAD	chr2	74522586	Missense_Mutation	rs200353206	L497F	0.19	HA2
COAD	chr2	74524068	Missense_Mutation	NA	I224R	0.34
COAD	chr2	74524272	Missense_Mutation	novel	A156V	0.3
COAD	chr2	74523337	Silent	novel	V339V	0.16
COAD	chr2	74518433	3'UTR	rs191808886		0.28
COAD	chr2	74518387	3'UTR	novel		0.36
COAD	chr2	74524081	Missense_Mutation	NA	P220A	0.29
COAD	chr2	74525696	Missense_Mutation	novel	Y12H	0.2
ESCA	chr2	74518513	Missense_Mutation	novel	A696E	0.18
ESCA	chr2	74519146	Nonsense_Mutation	rs755414819	R631*	0.1
GBM	chr2	74525145	Frame_Shift_Ins	novel	*T99Afs24**	0.37
GBM	chr2	74523958	Missense_Mutation	novel	P261A	0.35
GBM	chr2	74520016	Missense_Mutation	rs200754645	R505H	0.26	HA2
GBM	chr2	74518321	3'UTR	novel		0.4
GBM	chr2	74518355	3'UTR	novel		0.26
GBM	chr2	74518389	3'UTR	novel		0.18
GBM	chr2	74520016	Missense_Mutation	rs200754645	R505H	0.2	HA2
GBM	chr2	74524084	Missense_Mutation	novel	P219A	0.18
HNSC	chr2	74523343	Missense_Mutation	novel	Q337H	0.19
HNSC	chr2	74519586	Silent	novel	Q592Q	0.38
HNSC	chr2	74523367	Silent	novel	F329F	0.21
HNSC	chr2	74518511	Missense_Mutation	rs201394061	D697N	0.14
HNSC	chr2	74525088	Missense_Mutation	novel	E118Q	0.1
KIRC	chr2	74518515	Missense_Mutation	rs554672292	M695I	0.25
LAML	chr2	74522581	Splice_Region	novel	T498T	0.05
LGG	chr2	74522894	Missense_Mutation	NA	I422T	0.39
LGG	chr2	74519965	Missense_Mutation	rs201543859	T522M	0.1
LIHC	chr2	74518581	Silent	NA	P673P	0.17
LIHC	chr2	74523949	Missense_Mutation	NA	V264M	0.41
LIHC	chr2	74525517	Silent	novel	E71E	0.18
LIHC	chr2	74525166	Missense_Mutation	novel	G92R	0.05
LUAD	chr2	74518504	Missense_Mutation	novel	T699R	0.28
LUAD	chr2	74525119	Silent	NA	A107A	0.13
LUAD	chr2	74523465	Missense_Mutation	rs201047482	V297I	0.22
LUAD	chr2	74525044	Silent	novel	P132P	0.08
LUAD	chr2	74522643	Missense_Mutation	novel	L478M	0.63	HA2
LUAD	chr2	74524226	Missense_Mutation	NA	E171D	0.13
LUAD	chr2	74522745	Missense_Mutation	NA	E444K	0.21	HA2
LUAD	chr2	74524215	Missense_Mutation	rs376450262	R175L	0.29
LUAD	chr2	74518468	Missense_Mutation	NA	R711K	0.18
LUSC	chr2	74523490	Frame_Shift_Del	novel	*L288Ffs74**	0.2
LUSC	chr2	74523530	Missense_Mutation	NA	S275F	0.25
LUSC	chr2	74522951	Missense_Mutation	NA	P403H	0.23
LUSC	chr2	74519943	Silent	NA	L529L	0.24
LUSC	chr2	74523183	Silent	novel	V360V	0.24
LUSC	chr2	74523017	Splice_Region	novel		0.24
LUSC	chr2	74522951	Missense_Mutation	novel	P403L	0.07
LUSC	chr2	74523952	Missense_Mutation	novel	D263H	0.15
LUSC	chr2	74522910	Missense_Mutation	novel	L417V	0.15
OV	chr2	74524038	Missense_Mutation	NA	P234L	0.36
OV	chr2	74518362	3'UTR	novel		0.16
OV	chr2	74519658	Missense_Mutation	NA	E568D	0.3
PAAD	chr2	74522711	Missense_Mutation	novel	D455G	0.04	HA2
READ	chr2	74519565	Nonsense_Mutation	NA	Y599*	0.18
READ	chr2	74526646	5'Flank	novel		0.32
READ	chr2	74524009	Missense_Mutation	rs369001474	R244W	0.57
READ	chr2	74518334	3'UTR	novel		0.24
SARC	chr2	74523381	Missense_Mutation	novel	W325G	0.11
SARC	chr2	74523955	Missense_Mutation	novel	G262R	0.14
SARC	chr2	74525045	Missense_Mutation	novel	P132L	0.1
SKCM	chr2	74523020	Splice_Region	novel		0.53
SKCM	chr2	74519647	Missense_Mutation	rs753263732	R572Q	0.31
SKCM	chr2	74524243	Missense_Mutation	rs574005605	V166M	0.45
SKCM	chr2	74523359	Missense_Mutation	novel	S332F	0.14
SKCM	chr2	74523401	Missense_Mutation	rs749983331	R318Q	0.27
SKCM	chr2	74519229	Missense_Mutation	novel	V603E	0.25
SKCM	chr2	74524263	Missense_Mutation	rs766343104	R159Q	0.57
SKCM	chr2	74523530	Missense_Mutation	NA	S275F	0.29
SKCM	chr2	74523126	Silent	rs146840492	F379F	0.42
SKCM	chr2	74523526	Silent	novel	L276L	0.49
SKCM	chr2	74522669	Missense_Mutation	NA	P469L	0.26	HA2
SKCM	chr2	74519163	Missense_Mutation	novel	S625F	0.15
SKCM	chr2	74522658	Missense_Mutation	novel	E473K	0.23	HA2
SKCM	chr2	74524299	Nonsense_Mutation	novel	W147*	0.07
SKCM	chr2	74523958	Missense_Mutation	NA	P261S	0.53
SKCM	chr2	74522902	Silent	NA	R419R	0.09
SKCM	chr2	74523333	Missense_Mutation	rs771135773	D341N	0.32
SKCM	chr2	74520031	Missense_Mutation	NA	A500V	0.18	HA2
SKCM	chr2	74523021	Splice_Region	novel		0.45
SKCM	chr2	74523478	Silent	novel	G292G	0.19
SKCM	chr2	74524029	Nonsense_Mutation	rs764272497	W237*	0.2
SKCM	chr2	74524165	Missense_Mutation	novel	E192K	0.21
SKCM	chr2	74519211	Missense_Mutation	NA	G609E	0.22
SKCM	chr2	74522966	Missense_Mutation	NA	P398L	0.41
STAD	chr2	74519188	Missense_Mutation	NA	T617P	0.26
STAD	chr2	74519652	Missense_Mutation	rs759725464	M570I	0.37
STAD	chr2	74520027	Frame_Shift_Ins	novel	*G502Wfs24**	0.37	HA2
STAD	chr2	74519072	Nonsense_Mutation	NA	C655*	0.3
STAD	chr2	74523328	Silent	novel	S342S	0.36
STAD	chr2	74523404	Missense_Mutation	NA	A317V	0.18
STAD	chr2	74519684	Missense_Mutation	novel	H560Y	0.25
STAD	chr2	74522669	Missense_Mutation	NA	P469L	0.5	HA2
STAD	chr2	74524170	Missense_Mutation	novel	R190M	0.35
STAD	chr2	74525074	Silent	novel	T122T	0.43
STAD	chr2	74523315	Nonsense_Mutation	rs774452490	R347*	0.23
STAD	chr2	74518582	Missense_Mutation	NA	P673L	0.39
STAD	chr2	74523369	Missense_Mutation	NA	F329V	0.09
STAD	chr2	74523140	Nonsense_Mutation	rs150420269	R375*	0.09
STAD	chr2	74519740	Missense_Mutation	NA	A541G	0.18
STAD	chr2	74518455	Silent	novel	V715V	0.33
STAD	chr2	74522580	Missense_Mutation	NA	A499S	0.16	HA2
UCEC	chr2	74519647	Missense_Mutation	rs753263732	R572Q	0.31
UCEC	chr2	74519647	Missense_Mutation	rs753263732	R572Q	0.39
UCEC	chr2	74524177	Missense_Mutation	novel	D188Y	0.07
UCEC	chr2	74524206	Missense_Mutation	NA	A178V	0.26
UCEC	chr2	74518511	Missense_Mutation	NA	D697Y	0.35
UCEC	chr2	74519145	Missense_Mutation	rs369639265	R631Q	0.62
UCEC	chr2	74519925	Silent	novel	A535A	0.34
UCEC	chr2	74518455	Silent	NA	V715V	0.54
UCEC	chr2	74519675	Missense_Mutation	rs138905883	R563W	0.19
UCEC	chr2	74519165	Silent	NA	L624L	0.23
UCEC	chr2	74518446	Nonstop_Mutation	novel	718Cext15	0.2
UCEC	chr2	74519145	Missense_Mutation	rs369639265	R631Q	0.46
UCEC	chr2	74522933	Missense_Mutation	NA	N409S	0.12
UCEC	chr2	74519717	Nonsense_Mutation	rs779621715	R549*	0.38
UCEC	chr2	74518351	3'UTR	novel		0.17
UCEC	chr2	74523970	Missense_Mutation	rs773689288	R257W	0.39
UCEC	chr2	74525075	Missense_Mutation	NA	T122S	0.12
UCEC	chr2	74523022	Intron	novel		0.45
UCEC	chr2	74519940	Silent	novel	I530I	0.17
UCEC	chr2	74522946	Missense_Mutation	novel	V405M	0.31
UCEC	chr2	74524125	Missense_Mutation	novel	D205G	0.43
UCEC	chr2	74518455	Silent	NA	V715V	0.4
UCEC	chr2	74519594	Missense_Mutation	novel	D590Y	0.18
UCEC	chr2	74524268	Silent	rs140454701	S157S	0.64
UCEC	chr2	74523028	Intron	novel		0.43
UCEC	chr2	74525048	Missense_Mutation	novel	I131T	0.46
UCEC	chr2	74523334	Silent	rs746815800	I340I	0.47
UCEC	chr2	74518310	3'UTR	novel		0.68
UCEC	chr2	74518310	3'UTR	novel		0.39
UCEC	chr2	74519153	Silent	NA	C628C	0.38
UCEC	chr2	74522892	Missense_Mutation	novel	A423T	0.42

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	DEL	0.0243	0.08832
PAAD	DEL	0.0489	0.2014
READ	DEL	0.0727	0.19022

Survival Analysis

Cancer	P-value	Q-value
MESO	0.019	Kaplan-Meier Survival Analysis
ACC	0.00028	Kaplan-Meier Survival Analysis
SKCM	0.0067	Kaplan-Meier Survival Analysis
PRAD	0.029	Kaplan-Meier Survival Analysis
LUSC	0.0015	Kaplan-Meier Survival Analysis
KIRP	0.0028	Kaplan-Meier Survival Analysis
BLCA	0.018	Kaplan-Meier Survival Analysis
LIHC	0.05	Kaplan-Meier Survival Analysis
DLBC	0.032	Kaplan-Meier Survival Analysis
UVM	0.001	Kaplan-Meier Survival Analysis