EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000144134 (Gene tree)
Gene ID: 11159
Gene Symbol: RABL2A
Alias: -
Full Name: RAB, member of RAS oncogene family like 2A
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 16,170 bases
Position: chr2:113,627,229-113,643,398
Accession: 9799
RBP type: canonical RBP
Summary: This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000376871	MMR_HSR1	PF01926.23	0.00014	1	1
ENSP00000376872	MMR_HSR1	PF01926.23	0.00014	1	1
ENSP00000376870	MMR_HSR1	PF01926.23	0.00014	1	1
ENSP00000387229	MMR_HSR1	PF01926.23	0.00015	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000450954	RABL2A-209	2041	-	ENSP00000399360	101 (aa)	-	E7EWW3
ENST00000409875	RABL2A-207	2282	XM_006712208	ENSP00000387229	238 (aa)	XP_006712271	Q9UBK7
ENST00000478880	RABL2A-215	1776	-	-	- (aa)	-	-
ENST00000376439	RABL2A-201	623	-	ENSP00000365622	165 (aa)	-	B7ZBD5
ENST00000393165	RABL2A-202	1118	XM_017003213	ENSP00000376870	229 (aa)	XP_016858702	Q9UBK7
ENST00000393167	RABL2A-204	2179	XM_017003220	ENSP00000376872	228 (aa)	XP_016858709	Q9UBK7
ENST00000393166	RABL2A-203	1052	-	ENSP00000376871	228 (aa)	-	Q9UBK7
ENST00000409842	RABL2A-206	1979	XM_017003223	ENSP00000386460	165 (aa)	XP_016858712	B7ZBD5
ENST00000465711	RABL2A-211	917	-	-	- (aa)	-	-
ENST00000493876	RABL2A-217	642	-	-	- (aa)	-	-
ENST00000494909	RABL2A-218	2904	-	-	- (aa)	-	-
ENST00000476236	RABL2A-213	1109	-	-	- (aa)	-	-
ENST00000486403	RABL2A-216	2486	-	-	- (aa)	-	-
ENST00000477218	RABL2A-214	575	-	-	- (aa)	-	-
ENST00000452831	RABL2A-210	1944	-	ENSP00000415510	54 (aa)	-	F2Z2E5
ENST00000409121	RABL2A-205	2232	-	-	- (aa)	-	-
ENST00000413545	RABL2A-208	556	-	ENSP00000388944	114 (aa)	-	B7ZBD4
ENST00000467600	RABL2A-212	885	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000144134's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000144134	rs4849254	2	113638251	T	Diastolic blood pressure	28135244	[0.091-0.225] unit increase	0.1581	EFO_0006336

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000144134's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000144134	RABL2A	100	79.825	ENSAPOG00000023708	rabl2	99	73.182	Acanthochromis_polyacanthus
ENSG00000144134	RABL2A	100	88.136	ENSAMEG00000003173	-	99	87.111	Ailuropoda_melanoleuca
ENSG00000144134	RABL2A	100	78.070	ENSACIG00000000670	rabl2	92	74.510	Amphilophus_citrinellus
ENSG00000144134	RABL2A	98	82.828	ENSAOCG00000008069	rabl2	99	73.636	Amphiprion_ocellaris
ENSG00000144134	RABL2A	100	79.825	ENSAPEG00000003164	rabl2	99	72.727	Amphiprion_percula
ENSG00000144134	RABL2A	98	82.828	ENSATEG00000001111	rabl2	99	73.636	Anabas_testudineus
ENSG00000144134	RABL2A	92	89.524	ENSACAG00000000418	-	93	85.366	Anolis_carolinensis
ENSG00000144134	RABL2A	100	97.368	ENSANAG00000021001	-	100	95.197	Aotus_nancymaae
ENSG00000144134	RABL2A	98	81.818	ENSACLG00000025632	rabl2	92	77.073	Astatotilapia_calliptera
ENSG00000144134	RABL2A	100	81.579	ENSAMXG00000040611	rabl2	96	77.465	Astyanax_mexicanus
ENSG00000144134	RABL2A	100	93.860	ENSBTAG00000004876	RABL2B	99	85.714	Bos_taurus
ENSG00000144134	RABL2A	100	95.833	ENSCJAG00000018414	-	100	94.760	Callithrix_jacchus
ENSG00000144134	RABL2A	100	92.105	ENSCAFG00020006938	-	99	89.140	Canis_lupus_dingo
ENSG00000144134	RABL2A	100	92.982	ENSCHIG00000000591	-	99	84.716	Capra_hircus
ENSG00000144134	RABL2A	100	92.982	ENSTSYG00000004323	-	100	88.646	Carlito_syrichta
ENSG00000144134	RABL2A	98	94.949	ENSCPOG00000026899	-	98	90.323	Cavia_porcellus
ENSG00000144134	RABL2A	100	97.222	ENSCCAG00000025944	-	100	95.633	Cebus_capucinus
ENSG00000144134	RABL2A	100	95.833	ENSCATG00000034307	-	100	94.323	Cercocebus_atys
ENSG00000144134	RABL2A	100	94.737	ENSCLAG00000017218	-	99	89.593	Chinchilla_lanigera
ENSG00000144134	RABL2A	100	97.222	ENSCSAG00000004698	-	100	94.805	Chlorocebus_sabaeus
ENSG00000144134	RABL2A	92	87.619	ENSCPBG00000011715	-	93	81.043	Chrysemys_picta_bellii
ENSG00000144134	RABL2A	93	65.094	ENSCING00000004961	-	87	65.608	Ciona_intestinalis
ENSG00000144134	RABL2A	83	72.632	ENSCSAVG00000006042	-	89	65.591	Ciona_savignyi
ENSG00000144134	RABL2A	100	94.737	ENSCANG00000030879	-	100	93.450	Colobus_angolensis_palliatus
ENSG00000144134	RABL2A	100	92.105	ENSCGRG00001021894	Rabl2	99	87.783	Cricetulus_griseus_chok1gshd
ENSG00000144134	RABL2A	100	76.316	ENSCSEG00000005479	rabl2	97	73.272	Cynoglossus_semilaevis
ENSG00000144134	RABL2A	93	82.075	ENSCVAG00000011432	rabl2	96	73.585	Cyprinodon_variegatus
ENSG00000144134	RABL2A	93	79.245	ENSDARG00000063321	rabl2	99	73.853	Danio_rerio
ENSG00000144134	RABL2A	100	91.228	ENSDNOG00000035151	-	99	90.498	Dasypus_novemcinctus
ENSG00000144134	RABL2A	100	93.860	ENSDORG00000000003	Rabl2	99	90.498	Dipodomys_ordii
ENSG00000144134	RABL2A	100	91.228	ENSEASG00005008239	-	99	87.783	Equus_asinus_asinus
ENSG00000144134	RABL2A	100	91.228	ENSECAG00000026942	-	99	87.330	Equus_caballus
ENSG00000144134	RABL2A	100	92.982	ENSFCAG00000033642	-	99	89.593	Felis_catus
ENSG00000144134	RABL2A	100	92.105	ENSFDAG00000002113	-	100	85.590	Fukomys_damarensis
ENSG00000144134	RABL2A	100	79.825	ENSFHEG00000015015	rabl2	78	75.845	Fundulus_heteroclitus
ENSG00000144134	RABL2A	100	75.439	ENSGMOG00000018928	rabl2	100	75.635	Gadus_morhua
ENSG00000144134	RABL2A	100	74.561	ENSGALG00000032458	RABL2B	99	76.364	Gallus_gallus
ENSG00000144134	RABL2A	93	81.132	ENSGAFG00000005188	rabl2	95	73.934	Gambusia_affinis
ENSG00000144134	RABL2A	99	76.991	ENSGACG00000012474	rabl2	99	72.273	Gasterosteus_aculeatus
ENSG00000144134	RABL2A	98	81.818	ENSHBUG00000010964	rabl2	92	77.073	Haplochromis_burtoni
ENSG00000144134	RABL2A	100	92.982	ENSHGLG00000005750	-	99	88.688	Heterocephalus_glaber_female
ENSG00000144134	RABL2A	100	92.982	ENSHGLG00100016281	-	99	88.688	Heterocephalus_glaber_male
ENSG00000144134	RABL2A	100	92.982	ENSSTOG00000002723	-	99	91.855	Ictidomys_tridecemlineatus
ENSG00000144134	RABL2A	100	92.982	ENSJJAG00000010792	Rabl2	99	88.235	Jaculus_jaculus
ENSG00000144134	RABL2A	98	81.818	ENSKMAG00000012723	rabl2	99	73.636	Kryptolebias_marmoratus
ENSG00000144134	RABL2A	100	79.825	ENSLBEG00000003644	rabl2	99	73.182	Labrus_bergylta
ENSG00000144134	RABL2A	100	80.702	ENSLACG00000003722	rabl2	96	78.241	Latimeria_chalumnae
ENSG00000144134	RABL2A	100	80.702	ENSLOCG00000016767	rabl2	100	74.672	Lepisosteus_oculatus
ENSG00000144134	RABL2A	100	97.222	ENSMFAG00000044775	-	100	95.633	Macaca_fascicularis
ENSG00000144134	RABL2A	100	97.222	ENSMMUG00000022914	RABL2B	100	95.633	Macaca_mulatta
ENSG00000144134	RABL2A	100	96.491	ENSMNEG00000028460	-	100	95.175	Macaca_nemestrina
ENSG00000144134	RABL2A	100	94.737	ENSMLEG00000032621	-	100	94.737	Mandrillus_leucophaeus
ENSG00000144134	RABL2A	100	78.947	ENSMAMG00000008168	rabl2	99	72.727	Mastacembelus_armatus
ENSG00000144134	RABL2A	98	81.818	ENSMZEG00005019758	rabl2	96	75.481	Maylandia_zebra
ENSG00000144134	RABL2A	98	92.929	ENSMAUG00000010955	Rabl2	99	87.330	Mesocricetus_auratus
ENSG00000144134	RABL2A	100	93.860	ENSMICG00000031301	-	100	92.140	Microcebus_murinus
ENSG00000144134	RABL2A	98	92.929	ENSMOCG00000002775	Rabl2	99	86.364	Microtus_ochrogaster
ENSG00000144134	RABL2A	89	94.444	ENSMODG00000010838	-	97	85.915	Monodelphis_domestica
ENSG00000144134	RABL2A	100	78.070	ENSMALG00000005944	rabl2	99	72.727	Monopterus_albus
ENSG00000144134	RABL2A	98	90.909	MGP_CAROLIEiJ_G0020176	Rabl2	98	84.163	Mus_caroli
ENSG00000144134	RABL2A	98	88.889	ENSMUSG00000022621	Rabl2	99	83.710	Mus_musculus
ENSG00000144134	RABL2A	98	89.899	MGP_PahariEiJ_G0020181	Rabl2	99	84.163	Mus_pahari
ENSG00000144134	RABL2A	98	88.889	MGP_SPRETEiJ_G0021073	Rabl2	99	83.258	Mus_spretus
ENSG00000144134	RABL2A	100	92.105	ENSMPUG00000001806	-	99	89.140	Mustela_putorius_furo
ENSG00000144134	RABL2A	100	91.228	ENSNGAG00000012843	Rabl2	95	86.758	Nannospalax_galili
ENSG00000144134	RABL2A	100	79.825	ENSNBRG00000000489	rabl2	92	77.073	Neolamprologus_brichardi
ENSG00000144134	RABL2A	100	95.633	ENSNLEG00000030435	-	100	95.633	Nomascus_leucogenys
ENSG00000144134	RABL2A	100	92.105	ENSODEG00000015650	-	98	89.450	Octodon_degus
ENSG00000144134	RABL2A	98	82.828	ENSONIG00000014885	rabl2	100	70.996	Oreochromis_niloticus
ENSG00000144134	RABL2A	100	75.439	ENSORLG00000009874	rabl2	92	73.430	Oryzias_latipes
ENSG00000144134	RABL2A	100	75.439	ENSORLG00020001721	rabl2	92	73.430	Oryzias_latipes_hni
ENSG00000144134	RABL2A	100	75.439	ENSORLG00015014268	rabl2	92	73.430	Oryzias_latipes_hsok
ENSG00000144134	RABL2A	100	77.193	ENSOMEG00000008576	rabl2	95	74.396	Oryzias_melastigma
ENSG00000144134	RABL2A	100	93.860	ENSOGAG00000009123	-	100	90.830	Otolemur_garnettii
ENSG00000144134	RABL2A	100	92.982	ENSPPRG00000014642	-	96	89.041	Panthera_pardus
ENSG00000144134	RABL2A	100	92.982	ENSPTIG00000018747	-	99	89.593	Panthera_tigris_altaica
ENSG00000144134	RABL2A	100	98.246	ENSPTRG00000014555	-	100	97.059	Pan_troglodytes
ENSG00000144134	RABL2A	100	95.614	ENSPANG00000036121	-	100	94.538	Papio_anubis
ENSG00000144134	RABL2A	92	81.905	ENSPKIG00000025372	rabl2	88	81.122	Paramormyrops_kingsleyae
ENSG00000144134	RABL2A	92	89.524	ENSPSIG00000014041	-	93	82.464	Pelodiscus_sinensis
ENSG00000144134	RABL2A	99	76.106	ENSPMGG00000012946	rabl2	96	76.142	Periophthalmus_magnuspinnatus
ENSG00000144134	RABL2A	98	92.929	ENSPEMG00000024045	Rabl2	99	85.973	Peromyscus_maniculatus_bairdii
ENSG00000144134	RABL2A	94	93.651	ENSPCIG00000012436	-	89	83.636	Phascolarctos_cinereus
ENSG00000144134	RABL2A	92	83.810	ENSPFOG00000017960	rabl2	95	74.882	Poecilia_formosa
ENSG00000144134	RABL2A	92	83.810	ENSPLAG00000015685	rabl2	95	75.598	Poecilia_latipinna
ENSG00000144134	RABL2A	92	83.810	ENSPMEG00000004703	rabl2	95	75.598	Poecilia_mexicana
ENSG00000144134	RABL2A	93	82.075	ENSPREG00000014761	rabl2	94	78.307	Poecilia_reticulata
ENSG00000144134	RABL2A	100	97.849	ENSPPYG00000012000	-	100	96.507	Pongo_abelii
ENSG00000144134	RABL2A	100	92.982	ENSPCOG00000024865	-	100	92.576	Propithecus_coquereli
ENSG00000144134	RABL2A	100	92.105	ENSPVAG00000004539	-	100	86.076	Pteropus_vampyrus
ENSG00000144134	RABL2A	98	81.818	ENSPNYG00000004845	rabl2	92	77.073	Pundamilia_nyererei
ENSG00000144134	RABL2A	100	80.702	ENSPNAG00000024254	rabl2	99	75.676	Pygocentrus_nattereri
ENSG00000144134	RABL2A	98	91.919	ENSRNOG00000013947	Rabl2	88	85.520	Rattus_norvegicus
ENSG00000144134	RABL2A	100	94.737	ENSRBIG00000033607	-	100	94.323	Rhinopithecus_bieti
ENSG00000144134	RABL2A	100	95.833	ENSRROG00000031130	-	100	95.197	Rhinopithecus_roxellana
ENSG00000144134	RABL2A	100	97.222	ENSSBOG00000033266	-	100	95.633	Saimiri_boliviensis_boliviensis
ENSG00000144134	RABL2A	100	77.193	ENSSFOG00015020738	rabl2	98	73.853	Scleropages_formosus
ENSG00000144134	RABL2A	98	83.838	ENSSMAG00000004606	rabl2	93	76.812	Scophthalmus_maximus
ENSG00000144134	RABL2A	98	82.828	ENSSDUG00000014765	rabl2	99	73.182	Seriola_dumerili
ENSG00000144134	RABL2A	98	92.929	ENSSSCG00000025041	-	100	90.588	Sus_scrofa
ENSG00000144134	RABL2A	89	76.471	ENSTGUG00000016028	-	98	76.471	Taeniopygia_guttata
ENSG00000144134	RABL2A	100	78.947	ENSTRUG00000012454	rabl2	99	72.727	Takifugu_rubripes
ENSG00000144134	RABL2A	100	78.070	ENSTNIG00000017951	rabl2	99	72.273	Tetraodon_nigroviridis
ENSG00000144134	RABL2A	100	92.105	ENSUAMG00000015761	-	98	82.456	Ursus_americanus
ENSG00000144134	RABL2A	100	92.105	ENSUMAG00000017116	-	99	89.593	Ursus_maritimus
ENSG00000144134	RABL2A	100	92.105	ENSVVUG00000025761	-	99	88.235	Vulpes_vulpes
ENSG00000144134	RABL2A	98	80.808	ENSXETG00000015712	rabl2b	100	74.892	Xenopus_tropicalis
ENSG00000144134	RABL2A	93	83.019	ENSXMAG00000004569	rabl2	95	74.882	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005623	cell	-	IEA	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0032482	Rab protein signal transduction	21873635.	IBA	Process