EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000145041 (Gene tree)
Gene ID: 9730
Gene Symbol: DCAF1
Alias: KIAA0800|MGC102804|VPRBP
Full Name: DDB1 and CUL4 associated factor 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 109,752 bases
Position: chr3:51,395,867-51,505,618
Accession: 30911
RBP type: non-canonical RBP
Summary: (DDB1 And CUL4 Associated Factor 1) is a Protein Coding gene. Diseases associated with DCAF1 include Aicardi-Goutieres Syndrome. Among its related pathways are Human cytomegalovirus infection and Class I MHC mediated antigen processing and presentation.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28902349	TUG1 promotes osteosarcoma tumorigenesis by upregulating EZH2 expression via miR-144-3p.	Int J Oncol	2017 Oct	Cao J	doi: 10.3892/ijo.2017.4110

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000423656	DCAF1-202	5946	XM_005276753	ENSP00000393183	1507 (aa)	XP_005276810	Q9Y4B6
ENST00000335891	DCAF1-201	4114	-	ENSP00000338857	1058 (aa)	-	Q9Y4B6
ENST00000504652	DCAF1-203	5951	-	ENSP00000421724	1506 (aa)	-	Q9Y4B6

Gene Model

Click here to download ENSG00000145041's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05170	Human immunodeficiency virus 1 infection	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000145041	Education	3E-8	27225129

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000145041	rs35971989	3	51431798	A	Educational attainment (years of education)	27225129	NR unit increase	0.017542955	EFO_0004784
ENSG00000145041	rs56224965	3	51494264	A	Educational attainment (MTAG)	30038396	[0.0087-0.0169] unit decrease	0.0128	EFO_0004784
ENSG00000145041	rs56224965	3	51494264	A	Highest math class taken (MTAG)	30038396	[0.012-0.022] unit decrease	0.0167	EFO_0004875
ENSG00000145041	rs62257549	3	51488660	G	Allergic rhinitis	30013184	[1.03-1.06]	1.0526316	EFO_0005854
ENSG00000145041	rs73078636	3	51403873	?	Respiratory diseases	30595370			EFO_0000684

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000145041's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	24140421.	IDA	Process
GO:0001650	fibrillar center	-	IDA	Component
GO:0005515	protein binding	16949367.19264781.20178741.22157821.22190034.24336198.24412650.25026211.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	20178741.	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0008180	COP9 signalosome	18850735.	IDA	Component
GO:0016032	viral process	-	IEA	Process
GO:0016567	protein ubiquitination	-	IEA	Process
GO:0030183	B cell differentiation	-	ISS	Process
GO:0030331	estrogen receptor binding	21873635.	IBA	Function
GO:0030331	estrogen receptor binding	28068668.	IPI	Function
GO:0033151	V(D)J recombination	-	ISS	Process
GO:0035212	cell competition in a multicellular organism	20644714.	IMP	Process
GO:0080008	Cul4-RING E3 ubiquitin ligase complex	21873635.	IBA	Component
GO:0080008	Cul4-RING E3 ubiquitin ligase complex	16949367.	IDA	Component
GO:1990244	histone kinase activity (H2A-T120 specific)	21873635.	IBA	Function
GO:1990244	histone kinase activity (H2A-T120 specific)	24140421.	IDA	Function
GO:1990245	histone H2A-T120 phosphorylation	21873635.	IBA	Process
GO:1990245	histone H2A-T120 phosphorylation	24140421.	IDA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
16888644	Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells.	Cell Death Differ	2007 Mar	Borgne-Sanchez A	-
19029839	Anti-tumor activity mediated by protein and peptide transduction of HIV viral protein R (Vpr).	Cancer Biol Ther	2009 Jan	Muthumani K	-
24140421	VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription.	Mol Cell	2013 Nov 7	Kim K	doi: 10.1016/j.molcel.2013.09.017
28416635	VprBP/DCAF1 Regulates the Degradation and Nonproteolytic Activation of the Cell Cycle Transcription Factor FoxM1.	Mol Cell Biol	2017 Jun 15	Wang X	doi: 10.1128/MCB.00609-16

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr3	51420196	Missense_Mutation	novel	S925C	0.68
BLCA	chr3	51420957	Silent	NA	F671F	0.24
BLCA	chr3	51398742	3'UTR	rs782400210		0.2
BLCA	chr3	51412450	Missense_Mutation	novel	D1381Y	0.2
BLCA	chr3	51427409	Missense_Mutation	NA	I604L	0.37
BLCA	chr3	51441748	Missense_Mutation	novel	M221I	0.42
BLCA	chr3	51420169	Missense_Mutation	rs114108730	R934Q	0.25
BLCA	chr3	51414033	Missense_Mutation	novel	R1283Q	0.28
BLCA	chr3	51440999	Missense_Mutation	novel	D367N	0.35
BLCA	chr3	51414852	In_Frame_Ins	novel	Y1203_D1204insTT	0.1
BLCA	chr3	51403175	Missense_Mutation	novel	A1478V	0.16
BRCA	chr3	51420574	Missense_Mutation	novel	R799H	0.23
BRCA	chr3	51441864	Nonsense_Mutation	novel	Q183*	0.11
BRCA	chr3	51403172	Missense_Mutation	NA	D1479V	0.43
BRCA	chr3	51441590	Missense_Mutation	novel	D274G	0.5
BRCA	chr3	51420910	Missense_Mutation	NA	N687S	0.2
BRCA	chr3	51414803	Missense_Mutation	NA	A1220T	0.24
BRCA	chr3	51413363	Missense_Mutation	NA	D1319N	0.14
BRCA	chr3	51441550	Missense_Mutation	NA	F287L	0.15
BRCA	chr3	51418706	Nonsense_Mutation	NA	S1136*	0.18
CESC	chr3	51419961	Silent	rs542435236	T1003T	0.63
CESC	chr3	51420479	Nonsense_Mutation	novel	R831*	0.36
CESC	chr3	51427483	Missense_Mutation	novel	G579D	0.35
CESC	chr3	51414806	Missense_Mutation	novel	L1219V	0.27
CESC	chr3	51427404	Silent	novel	S605S	0.12
CESC	chr3	51419918	Missense_Mutation	rs782065552	R1018C	0.52
CESC	chr3	51430049	Missense_Mutation	novel	R484H	0.29
CESC	chr3	51483735	Missense_Mutation	novel	V32I	0.48
CESC	chr3	51430136	Nonsense_Mutation	novel	S455*	0.37
CESC	chr3	51420526	Missense_Mutation	NA	R815Q	0.18
CESC	chr3	51420708	Silent	NA	I754I	0.13
CHOL	chr3	51412378	Splice_Site	novel	X1404_splice	0.71
COAD	chr3	51443846	Missense_Mutation	NA	T145A	0.25
COAD	chr3	51463130	Missense_Mutation	NA	V120A	0.29
COAD	chr3	51413016	Missense_Mutation	novel	D1363N	0.12
COAD	chr3	51414033	Missense_Mutation	novel	R1283Q	0.19
COAD	chr3	51420192	Silent	novel	A926A	0.31
COAD	chr3	51418727	Missense_Mutation	novel	A1129V	0.19
COAD	chr3	51420719	Missense_Mutation	novel	A751T	0.13
COAD	chr3	51419798	Missense_Mutation	NA	A1058T	0.28
COAD	chr3	51420656	Missense_Mutation	novel	R772W	0.46
COAD	chr3	51403197	Missense_Mutation	novel	G1471R	0.22
COAD	chr3	51470989	Nonsense_Mutation	NA	E43*	0.37
COAD	chr3	51413986	Missense_Mutation	NA	V1299M	0.36
COAD	chr3	51430128	Missense_Mutation	NA	C458R	0.41
COAD	chr3	51403320	Missense_Mutation	novel	D1430N	0.46
COAD	chr3	51430190	Missense_Mutation	novel	V437A	0.07
COAD	chr3	51419917	Missense_Mutation	NA	R1018H	0.31
COAD	chr3	51441680	In_Frame_Del	novel	M237_D244delinsI	0.08
COAD	chr3	51414706	Missense_Mutation	NA	I1252T	0.4
COAD	chr3	51440984	Missense_Mutation	NA	F372V	0.33
DLBC	chr3	51463131	Missense_Mutation	novel	V120I	0.38
ESCA	chr3	51414694	Missense_Mutation	novel	D1256G	0.24
ESCA	chr3	51418797	Missense_Mutation	novel	R1106W	0.34
GBM	chr3	51419752	Missense_Mutation	novel	R1073M	0.33
GBM	chr3	51403272	Missense_Mutation	rs372451907	A1446T	0.59
HNSC	chr3	51413375	Missense_Mutation	novel	A1315T	0.38
HNSC	chr3	51420381	Silent	novel	L863L	0.3
HNSC	chr3	51403241	Missense_Mutation	novel	P1456L	0.47
HNSC	chr3	51403242	Missense_Mutation	novel	P1456S	0.5
HNSC	chr3	51463210	Silent	novel	V93V	0.45
HNSC	chr3	51420664	Missense_Mutation	rs782701779	S769T	0.61
HNSC	chr3	51443872	Missense_Mutation	novel	A136V	0.13
HNSC	chr3	51420335	Missense_Mutation	NA	T879A	0.09
KIRC	chr3	51418145	Silent	rs782684307	L1163L	0.28
KIRP	chr3	51418717	Missense_Mutation	NA	N1132K	0.83
KIRP	chr3	51420168	Silent	NA	R934R	0.44
KIRP	chr3	51414859	Splice_Site	NA	X1202_splice	0.09
LAML	chr3	51441635	Missense_Mutation	novel	P259L	0.05
LAML	chr3	51429361	Missense_Mutation	NA	K526R	0.37
LGG	chr3	51420996	Splice_Region	novel	G658G	0.28
LIHC	chr3	51470995	Missense_Mutation	novel	L41M	0.49
LIHC	chr3	51441597	Frame_Shift_Del	novel	*Q272Rfs40**	0.3
LUAD	chr3	51441821	Missense_Mutation	NA	S197I	0.23
LUAD	chr3	51403272	Missense_Mutation	rs372451907	A1446T	0.5
LUAD	chr3	51420705	Silent	NA	R755R	0.23
LUAD	chr3	51420614	Missense_Mutation	novel	I786F	0.49
LUAD	chr3	51419804	Missense_Mutation	novel	R1056C	0.05
LUAD	chr3	51420086	Nonsense_Mutation	novel	E962*	0.19
LUAD	chr3	51403165	Missense_Mutation	NA	E1481D	0.54
LUAD	chr3	51483741	Missense_Mutation	novel	D30N	0.65
LUSC	chr3	51422407	Missense_Mutation	novel	L624F	0.36
LUSC	chr3	51420837	Frame_Shift_Del	novel	*L711Pfs5**	0.73
LUSC	chr3	51420534	Silent	rs568857340	L812L	0.19
LUSC	chr3	51441622	Silent	NA	G263G	0.41
LUSC	chr3	51420290	Missense_Mutation	NA	A894T	0.34
LUSC	chr3	51414684	Silent	NA	N1259N	0.28
LUSC	chr3	51430050	Missense_Mutation	NA	R484C	0.06
LUSC	chr3	51483731	Missense_Mutation	NA	P33R	0.28
LUSC	chr3	51427490	Missense_Mutation	novel	E577Q	0.33
LUSC	chr3	51414725	Missense_Mutation	novel	V1246I	0.65
LUSC	chr3	51441786	Missense_Mutation	novel	L209V	0.18
OV	chr3	51463199	Missense_Mutation	rs371807205	R97Q	0.09
OV	chr3	51420061	Missense_Mutation	novel	R970K	0.17
OV	chr3	51441553	Silent	novel	G286G	0.13
OV	chr3	51441016	Missense_Mutation	novel	D361G	0.08
OV	chr3	51416825	Missense_Mutation	novel	Q1189K	0.44
OV	chr3	51418733	Missense_Mutation	novel	E1127G	0.11
OV	chr3	51416866	Missense_Mutation	novel	S1175C	0.35
OV	chr3	51418854	Missense_Mutation	novel	R1087W	0.44
OV	chr3	51483756	Missense_Mutation	NA	H25Y	0.44
OV	chr3	51420648	Silent	rs781835730	I774I	0.17
OV	chr3	51420826	Missense_Mutation	rs782134454	P715L	0.05
PAAD	chr3	51419832	Silent	rs782480142	A1046A	0.21
PAAD	chr3	51420313	Missense_Mutation	novel	A886V	0.16
PAAD	chr3	51420666	Silent	novel	S768S	0.19
PCPG	chr3	51418166	Missense_Mutation	novel	W1156C	0.2
PRAD	chr3	51430198	Silent	novel	P434P	0.3
PRAD	chr3	51418726	Silent	rs556883362	A1129A	0.41
PRAD	chr3	51441466	Missense_Mutation	novel	N315K	0.36
READ	chr3	51413009	Missense_Mutation	rs782657004	Y1365C	0.18
READ	chr3	51413314	Missense_Mutation	NA	R1335Q	0.4
READ	chr3	51443901	Missense_Mutation	NA	E126D	0.38
READ	chr3	51471000	Missense_Mutation	NA	S39Y	0.42
READ	chr3	51414033	Missense_Mutation	novel	R1283Q	0.09
READ	chr3	51419910	Missense_Mutation	NA	K1020N	0.12
SKCM	chr3	51420236	Missense_Mutation	rs782593092	R912C	0.54
SKCM	chr3	51418873	Silent	NA	F1080F	0.33
SKCM	chr3	51413053	Silent	novel	V1350V	0.24
SKCM	chr3	51420657	Silent	novel	V771V	0.31
SKCM	chr3	51420708	Silent	NA	I754I	0.16
SKCM	chr3	51483830	5'UTR	novel		0.1
SKCM	chr3	51403246	Silent	NA	F1454F	0.33
SKCM	chr3	51441823	Silent	NA	P196P	0.47
SKCM	chr3	51430165	Silent	novel	T445T	0.27
SKCM	chr3	51441796	Silent	novel	P205P	0.05
SKCM	chr3	51441797	Missense_Mutation	NA	P205L	0.06
SKCM	chr3	51420433	Missense_Mutation	novel	P846H	0.5
SKCM	chr3	51483722	Missense_Mutation	NA	T36I	0.21
SKCM	chr3	51418166	Nonsense_Mutation	novel	W1156*	0.31
SKCM	chr3	51420366	Silent	rs782444653	T868T	0.3
SKCM	chr3	51420116	Missense_Mutation	rs782805061	P952S	0.44
SKCM	chr3	51413014	Silent	NA	D1363D	0.39
SKCM	chr3	51441815	Missense_Mutation	rs782390664	R199Q	0.12
SKCM	chr3	51441760	Silent	NA	D217D	0.33
SKCM	chr3	51418792	Silent	NA	F1107F	0.36
SKCM	chr3	51420671	Missense_Mutation	novel	R767C	0.38
SKCM	chr3	51414639	Silent	novel	I1274I	0.39
STAD	chr3	51419994	Frame_Shift_Del	NA	*K992Nfs16**	0.28
STAD	chr3	51414024	Missense_Mutation	novel	H1286L	0.16
STAD	chr3	51441699	Missense_Mutation	NA	E238K	0.41
STAD	chr3	51430164	Missense_Mutation	novel	L446M	0.23
STAD	chr3	51420408	Missense_Mutation	NA	I854M	0.08
STAD	chr3	51420656	Silent	NA	R772R	0.25
STAD	chr3	51463185	Missense_Mutation	NA	N102H	0.37
STAD	chr3	51419994	Frame_Shift_Del	NA	*K992Nfs16**	0.23
STAD	chr3	51418175	Silent	NA	S1153S	0.16
STAD	chr3	51419994	Frame_Shift_Del	NA	*K992Nfs16**	0.24
STAD	chr3	51427487	Missense_Mutation	NA	Y578H	0.24
STAD	chr3	51420912	Silent	NA	I686I	0.4
STAD	chr3	51420269	Nonsense_Mutation	NA	R901*	0.12
STAD	chr3	51441671	Missense_Mutation	novel	H247R	0.23
STAD	chr3	51441530	Missense_Mutation	NA	R294H	0.22
THYM	chr3	51463206	Missense_Mutation	novel	T95P	0.11
UCEC	chr3	51420030	Silent	novel	D980D	0.25
UCEC	chr3	51413297	Missense_Mutation	NA	D1341Y	0.23
UCEC	chr3	51418877	Splice_Site	NA	X1079_splice	0.36
UCEC	chr3	51403273	Silent	novel	N1445N	0.1
UCEC	chr3	51420406	Missense_Mutation	rs782490529	R855Q	0.29
UCEC	chr3	51483733	Silent	NA	V32V	0.3
UCEC	chr3	51420406	Missense_Mutation	rs782490529	R855Q	0.38
UCEC	chr3	51441667	Missense_Mutation	novel	K248N	0.24
UCEC	chr3	51413048	Missense_Mutation	NA	R1352Q	0.14
UCEC	chr3	51398656	Intron	novel		0.42
UCEC	chr3	51443887	Missense_Mutation	novel	N131T	0.33
UCEC	chr3	51443891	Missense_Mutation	NA	E130K	0.39
UCEC	chr3	51427483	Missense_Mutation	novel	G579D	0.1
UCEC	chr3	51420726	Missense_Mutation	NA	I748M	0.13
UCEC	chr3	51430049	Missense_Mutation	novel	R484H	0.34
UCEC	chr3	51414790	Missense_Mutation	novel	K1224T	0.27
UCEC	chr3	51427518	Missense_Mutation	NA	Q567H	0.33
UCEC	chr3	51441881	Missense_Mutation	rs781934030	R177Q	0.2
UCEC	chr3	51422417	Missense_Mutation	NA	R621L	0.45
UCEC	chr3	51419949	Frame_Shift_Ins	novel	*I1008Tfs10**	0.03
UCEC	chr3	51427502	Missense_Mutation	novel	E573K	0.11
UCEC	chr3	51413967	Missense_Mutation	novel	G1305V	0.2
UCEC	chr3	51429397	Missense_Mutation	NA	R514H	0.2
UCEC	chr3	51412439	Silent	NA	C1384C	0.17
UCEC	chr3	51403234	Silent	NA	D1458D	0.42
UCEC	chr3	51429334	Missense_Mutation	novel	K535T	0.37
UCEC	chr3	51420856	Missense_Mutation	NA	G705D	0.24
UCEC	chr3	51403303	Silent	novel	A1435A	0.34
UCEC	chr3	51412458	Missense_Mutation	novel	L1378P	0.23
UCEC	chr3	51414714	Silent	novel	A1249A	0.34
UCEC	chr3	51420576	Silent	novel	K798K	0.25
UCEC	chr3	51441460	Silent	novel	T317T	0.12
UCEC	chr3	51403330	Missense_Mutation	novel	E1426D	0.4
UCEC	chr3	51413368	Missense_Mutation	novel	D1317G	0.35
UCEC	chr3	51470967	Missense_Mutation	novel	R50H	0.64
UCEC	chr3	51414033	Missense_Mutation	novel	R1283Q	0.46
UCEC	chr3	51441705	Missense_Mutation	novel	D236Y	0.4
UCEC	chr3	51441881	Missense_Mutation	rs781934030	R177Q	0.41
UCEC	chr3	51420269	Silent	NA	R901R	0.35
UCEC	chr3	51418768	Silent	NA	G1115G	0.37
UCEC	chr3	51418175	Frame_Shift_Del	novel	*A1154Lfs13**	0.49
UCEC	chr3	51412391	Missense_Mutation	NA	E1400D	0.12
UCEC	chr3	51412378	Splice_Site	novel	X1404_splice	0.43
UCEC	chr3	51420479	Nonsense_Mutation	novel	R831*	0.1
UCEC	chr3	51414839	Missense_Mutation	novel	G1208S	0.62
UCEC	chr3	51418676	Splice_Site	NA	X1145_splice	0.35
UCEC	chr3	51420365	Missense_Mutation	rs781808236	V869M	0.43
UCEC	chr3	51429456	Missense_Mutation	novel	E494D	0.16
UCEC	chr3	51441583	Missense_Mutation	NA	E276D	0.17
UCEC	chr3	51414827	Silent	novel	L1212L	0.42
UCEC	chr3	51420443	Missense_Mutation	novel	I843L	0.42
UCEC	chr3	51470960	Silent	novel	G52G	0.52
UCEC	chr3	51420837	Silent	novel	L711L	0.24
UCEC	chr3	51422417	Missense_Mutation	NA	R621H	0.35
UCEC	chr3	51441583	Missense_Mutation	NA	E276D	0.39
UCEC	chr3	51483831	5'UTR	novel		0.43
UCEC	chr3	51441435	Missense_Mutation	novel	E326K	0.54
UCEC	chr3	51414033	Missense_Mutation	novel	R1283Q	0.92
UCEC	chr3	51429364	Missense_Mutation	novel	R525H	0.39
UCEC	chr3	51443891	Missense_Mutation	NA	E130K	0.45
UCEC	chr3	51441396	Nonsense_Mutation	novel	E339*	0.1
UCEC	chr3	51466820	Missense_Mutation	NA	D82Y	0.2
UCEC	chr3	51397129	Splice_Region	novel		0.2
UCEC	chr3	51414634	Missense_Mutation	novel	N1276T	0.31
UCEC	chr3	51443804	Missense_Mutation	novel	D159Y	0.12
UCEC	chr3	51416786	Splice_Site	NA	X1201_splice	0.32
UCEC	chr3	51420584	Frame_Shift_Ins	novel	*Q796Gfs9**	0.06
UCEC	chr3	51414685	Missense_Mutation	novel	N1259I	0.41
UCEC	chr3	51420401	Missense_Mutation	novel	H857Y	0.31
UCEC	chr3	51420406	Missense_Mutation	rs782490529	R855Q	0.45
UCEC	chr3	51470993	Missense_Mutation	NA	L41F	0.39
UCEC	chr3	51414033	Missense_Mutation	novel	R1283Q	0.1
UCEC	chr3	51420991	Missense_Mutation	novel	S660T	0.44
UCEC	chr3	51429441	Missense_Mutation	novel	E499D	0.37
UCEC	chr3	51413058	Missense_Mutation	novel	D1349Y	0.33
UCEC	chr3	51414798	Silent	novel	N1221N	0.18
UCEC	chr3	51416811	Silent	rs781879249	I1193I	0.67
UCEC	chr3	51418152	Missense_Mutation	novel	S1161F	0.18
UCEC	chr3	51430064	Missense_Mutation	novel	R479H	0.23
UCEC	chr3	51443818	Missense_Mutation	novel	A154V	0.13
UCEC	chr3	51466875	Splice_Region	novel	G63G	0.13
UCEC	chr3	51427393	Missense_Mutation	novel	N609T	0.28
UCEC	chr3	51416787	Splice_Region	rs200027144	H1201H	0.27
UCEC	chr3	51420220	Missense_Mutation	NA	A917V	0.27
UCEC	chr3	51422327	Missense_Mutation	NA	G651E	0.21
UCEC	chr3	51430064	Missense_Mutation	novel	R479H	0.04
UCEC	chr3	51420259	Missense_Mutation	NA	R904H	0.38
UCEC	chr3	51412481	Splice_Site	novel	X1371_splice	0.32
UCEC	chr3	51419917	Missense_Mutation	NA	R1018H	0.33
UCEC	chr3	51420259	Missense_Mutation	NA	R904H	0.26
UCEC	chr3	51420406	Missense_Mutation	rs782490529	R855Q	0.27
UCEC	chr3	51420451	Missense_Mutation	novel	Q840L	0.35
UCS	chr3	51466873	Missense_Mutation	novel	R64Q	0.49
UVM	chr3	51429369	Silent	novel	A523A	0.52

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CHOL	DEL	0.7778	0.016387
GBM	DEL	0.0815	0.056565
LGG	DEL	0.0819	0.00089193
LUAD	DEL	0.3333	0.0021265
PAAD	DEL	0.1902	0.030662
SARC	DEL	0.2218	0.0034746
SKCM	DEL	0.1635	0.13887
TGCT	AMP	0.14	0.23596
THYM	DEL	0.0813	0.037527

Survival Analysis

Cancer	P-value	Q-value
THYM	0.01	Kaplan-Meier Survival Analysis
KIRC	0.0023	Kaplan-Meier Survival Analysis
SARC	0.042	Kaplan-Meier Survival Analysis
MESO	0.035	Kaplan-Meier Survival Analysis
ACC	0.0057	Kaplan-Meier Survival Analysis
SKCM	0.036	Kaplan-Meier Survival Analysis
PRAD	0.025	Kaplan-Meier Survival Analysis
BRCA	0.037	Kaplan-Meier Survival Analysis
READ	0.00096	Kaplan-Meier Survival Analysis
LAML	0.043	Kaplan-Meier Survival Analysis
LIHC	0.0074	Kaplan-Meier Survival Analysis
CHOL	0.044	Kaplan-Meier Survival Analysis
UVM	0.00011	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742