EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000145907 (Gene tree)
Gene ID: 10146
Gene Symbol: G3BP1
Alias: HDH-VIII|G3BP
Full Name: G3BP stress granule assembly factor 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 41,741 bases
Position: chr5:151,771,045-151,812,785
Accession: 30292
RBP type: canonical RBP
Summary: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000348578	NTF2	PF02136.20	5e-32	1	1
ENSP00000377681	NTF2	PF02136.20	5e-32	1	1
ENSP00000429250	NTF2	PF02136.20	2.3e-29	1	1
ENSP00000429920	NTF2	PF02136.20	3.3e-27	1	1
ENSP00000430738	NTF2	PF02136.20	2.3e-21	1	1
ENSP00000428469	NTF2	PF02136.20	2.9e-21	1	1
ENSP00000348578	RRM_1	PF00076.22	9.6e-13	1	1
ENSP00000377681	RRM_1	PF00076.22	9.6e-13	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28794026	Mammalian Orthoreovirus Factories Modulate Stress Granule Protein Localization by Interaction with G3BP1.	J Virol	2017 Oct 13	Choudhury P	doi: 10.1128/JVI.01298-17
28523344	Role of G3BP1 in glucocorticoid receptor-mediated microRNA-15b and microRNA-23a biogenesis in endothelial cells.	Cell Mol Life Sci	2017 Oct	Kwok HH	doi: 10.1007/s00018-017-2540-y
31037644	Viral Regulation of RNA Granules in Infected Cells.	Virol Sin	2019 Apr	Zhang Q	doi: 10.1007/s12250-019-00122-3
25108040	Pathological stress granules in Alzheimer's disease.	Brain Res	2014 Oct 10	Ash PE	doi: 10.1016/j.brainres.2014.05.052
29463567	Single-molecule imaging reveals dynamic biphasic partition of RNA-binding proteins in stress granules.	J Cell Biol	2018 Apr 2	Niewidok B	doi: 10.1083/jcb.201709007
16407409	Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules.	Mol Biol Cell	2006 Mar	Hofmann I	-
21351580	[G3BP: a promising target for cancer therapy].	Yao Xue Xue Bao	2010 Aug	Zhang H	-
23881279	Plakophilin-associated RNA-binding proteins in prostate cancer and their implications in tumor progression and metastasis.	Virchows Arch	2013 Sep	Yang C	doi: 10.1007/s00428-013-1452-y
11604510	RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization.	Mol Cell Biol	2001 Nov	Tourriere H	-
30804210	The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-β response.	J Biol Chem	2019 Apr 19	Kim SS	doi: 10.1074/jbc.RA118.005868
18005751	Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase.	Cell Host Microbe	2007 Nov 15	White JP	-
28712408	[Dectection of G3BP and CD44v6 in the tissues of laryngeal squamous cell carcinoma and their clinical significance].	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi	2017 Jul	Luo D	-
30603102	SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists.	Cell Discov	2019 Jan 1	Yang X	doi: 10.1038/s41421-018-0068-4
8649363	A Ras-GTPase-activating protein SH3-domain-binding protein.	Mol Cell Biol	1996 Jun	Parker F	-
11146228	G3BP is overexpressed in human tumors and promotes S phase entry.	Cancer Lett	2001 Jan 26	Guitard E	-
15602692	Rasputin, more promiscuous than ever: a review of G3BP.	Int J Dev Biol	2004 Dec	Irvine K	-
20180778	The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation.	Biochem J	2010 Apr 14	Hinton SD	doi: 10.1042/BJ20091383.
18005740	Colocalization of transcription and translation within cytoplasmic poxvirus factories coordinates viral expression and subjugates host functions.	Cell Host Microbe	2007 Oct 11	Katsafanas GC	-
23213403	Wnt signalling antagonizes stress granule assembly through a Dishevelled-dependent mechanism.	Biol Open	2012 Feb 15	Sahoo PK	doi: 10.1242/bio.2011023
24992036	G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA.	PLoS Pathog	2014 Jul 3	Bidet K	doi: 10.1371/journal.ppat.1004242
25653451	Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication.	J Virol	2015 Apr	Scholte FE	doi: 10.1128/JVI.03612-14
25488811	Stress granules are dispensable for mRNA stabilization during cellular stress.	Nucleic Acids Res	2015 Feb 27	Bley N	doi: 10.1093/nar/gku1275
25225333	Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins.	Mol Cell Biol	2014 Dec 1	Fischer-Keso R	doi: 10.1128/MCB.00766-14
27481264	ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics.	Acta Neuropathol	2016 Oct	Gal J	doi: 10.1007/s00401-016-1601-x
27022092	G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.	J Cell Biol	2016 Mar 28	Kedersha N	doi: 10.1083/jcb.201508028.
28972166	Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1.	J Biol Chem	2017 Nov 17	Tsai WC	doi: 10.1074/jbc.M117.800706
29140688	RNA Chemical Proteomics Reveals the N6-Methyladenosine (m6A)-Regulated Protein-RNA Interactome.	J Am Chem Soc	2017 Dec 6	Arguello AE	doi: 10.1021/jacs.7b09213
31138677	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	J Cell Sci	2019 Jun 17	Das R	doi: 10.1242/jcs.229252.
31199850	Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery.	PLoS Pathog	2019 Jun 14	Gotte B	doi: 10.1371/journal.ppat.1007842
17210633	Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs.	Mol Cell Biol	2007 Mar	Solomon S	-
27749929	Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories.	PLoS Pathog	2016 Oct 17	Nikolic J	doi: 10.1371/journal.ppat.1005942
22855484	Hepatitis C virus (HCV) induces formation of stress granules whose proteins regulate HCV RNA replication and virus assembly and egress.	J Virol	2012 Oct	Garaigorta U	-
26339052	Doubly Spliced RNA of Hepatitis B Virus Suppresses Viral Transcription via TATA-Binding Protein and Induces Stress Granule Assembly.	J Virol	2015 Nov	Tsai KN	doi: 10.1128/JVI.00949-15
12587999	The expression of Ras-GTPase activating protein SH3 domain-binding proteins, G3BPs, in human breast cancers.	Histochem J	2002 May	French J	-
11746526	Characterization of G3BPs: tissue specific expression, chromosomal localisation and rasGAP(120) binding studies.	J Cell Biochem	2001	Kennedy D	-
23087212	Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection.	Mol Biol Cell	2012 Dec	Panas MD	doi: 10.1091/mbc.E12-08-0619
22837213	Chikungunya virus nsP3 blocks stress granule assembly by recruitment of G3BP into cytoplasmic foci.	J Virol	2012 Oct	Fros JJ	doi: 10.1128/JVI.01506-12
21561913	Hepatitis C virus co-opts Ras-GTPase-activating protein-binding protein 1 for its genome replication.	J Virol	2011 Jul	Yi Z	doi: 10.1128/JVI.00013-11
25658430	Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation.	PLoS Pathog	2015 Feb 6	Panas MD	doi: 10.1371/journal.ppat.1004659
24260247	Production of a dominant-negative fragment due to G3BP1 cleavage contributes to the disruption of mitochondria-associated protective stress granules during CVB3 infection.	PLoS One	2013 Nov 18	Fung G	doi: 10.1371/journal.pone.0079546

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000522761	G3BP1-212	1763	-	ENSP00000430480	153 (aa)	-	E5RJU8
ENST00000522666	G3BP1-211	783	-	ENSP00000429316	37 (aa)	-	E5RH00
ENST00000356245	G3BP1-201	2803	-	ENSP00000348578	466 (aa)	-	Q13283
ENST00000520006	G3BP1-207	754	-	ENSP00000428469	105 (aa)	-	E5RI46
ENST00000627077	G3BP1-214	114	-	ENSP00000486887	37 (aa)	-	E5RH00
ENST00000522367	G3BP1-210	580	-	ENSP00000428926	122 (aa)	-	Q13283
ENST00000394123	G3BP1-202	10240	-	ENSP00000377681	466 (aa)	-	Q13283
ENST00000517947	G3BP1-204	558	-	ENSP00000430045	37 (aa)	-	E5RH00
ENST00000507878	G3BP1-203	577	-	ENSP00000429250	148 (aa)	-	E5RIZ6
ENST00000518726	G3BP1-205	869	-	-	- (aa)	-	-
ENST00000519832	G3BP1-206	1173	-	-	- (aa)	-	-
ENST00000523519	G3BP1-213	535	-	ENSP00000430738	106 (aa)	-	E5RIF8
ENST00000520578	G3BP1-209	530	-	ENSP00000429920	117 (aa)	-	E5RH42
ENST00000520177	G3BP1-208	2700	-	ENSP00000427810	122 (aa)	-	Q13283

Gene Model

Click here to download ENSG00000145907's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000145907	Platelet Function Tests	3.0900000E-006	-
ENSG00000145907	Platelet Function Tests	3.3200000E-006	-
ENSG00000145907	Child Behavior	8E-6	24839885
ENSG00000145907	Alzheimer Disease	2E-7	26830138
ENSG00000145907	Age of Onset	2E-7	26830138

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000145907	rs186127414	5	151801825	A	Alzheimer disease and age of onset	26830138	unit increase	5.17	EFO_0000249\|EFO_0004847
ENSG00000145907	rs1062177	5	151805140	T	Preschool internalizing problems	24839885	[0.09-0.23] unit decrease	0.16	EFO_0005661

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000145907's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000145907	G3BP1	100	81.197	ENSG00000138757	G3BP2	100	83.929

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000145907	G3BP1	100	82.906	ENSAPOG00000024387	g3bp2	87	61.438	Acanthochromis_polyacanthus
ENSG00000145907	G3BP1	100	83.761	ENSAPOG00000019362	g3bp1	98	63.968	Acanthochromis_polyacanthus
ENSG00000145907	G3BP1	100	81.197	ENSAMEG00000014424	G3BP2	88	64.612	Ailuropoda_melanoleuca
ENSG00000145907	G3BP1	100	83.019	ENSAMEG00000001417	-	100	71.459	Ailuropoda_melanoleuca
ENSG00000145907	G3BP1	100	100.000	ENSAMEG00000007833	-	99	96.809	Ailuropoda_melanoleuca
ENSG00000145907	G3BP1	100	82.906	ENSACIG00000018498	g3bp2	87	59.361	Amphilophus_citrinellus
ENSG00000145907	G3BP1	100	83.761	ENSACIG00000024294	g3bp1	98	64.516	Amphilophus_citrinellus
ENSG00000145907	G3BP1	100	82.906	ENSAOCG00000023808	g3bp2	87	61.220	Amphiprion_ocellaris
ENSG00000145907	G3BP1	100	83.761	ENSAOCG00000012401	g3bp1	98	63.765	Amphiprion_ocellaris
ENSG00000145907	G3BP1	100	82.906	ENSAOCG00000023536	-	89	84.892	Amphiprion_ocellaris
ENSG00000145907	G3BP1	100	82.906	ENSAPEG00000013191	g3bp2	87	60.823	Amphiprion_percula
ENSG00000145907	G3BP1	100	83.761	ENSAPEG00000003082	g3bp1	98	64.170	Amphiprion_percula
ENSG00000145907	G3BP1	100	82.906	ENSATEG00000014140	g3bp2	87	64.692	Anabas_testudineus
ENSG00000145907	G3BP1	100	83.761	ENSATEG00000017646	g3bp1	100	72.297	Anabas_testudineus
ENSG00000145907	G3BP1	100	83.761	ENSAPLG00000013777	G3BP2	88	67.048	Anas_platyrhynchos
ENSG00000145907	G3BP1	100	89.744	ENSAPLG00000006581	G3BP1	99	86.296	Anas_platyrhynchos
ENSG00000145907	G3BP1	100	82.051	ENSACAG00000008695	G3BP2	88	63.554	Anolis_carolinensis
ENSG00000145907	G3BP1	100	88.034	ENSACAG00000009792	G3BP1	100	82.489	Anolis_carolinensis
ENSG00000145907	G3BP1	100	79.487	ENSANAG00000001631	-	73	80.769	Aotus_nancymaae
ENSG00000145907	G3BP1	98	87.500	ENSANAG00000035880	-	100	75.699	Aotus_nancymaae
ENSG00000145907	G3BP1	100	100.000	ENSANAG00000022416	-	100	99.571	Aotus_nancymaae
ENSG00000145907	G3BP1	99	80.769	ENSANAG00000032089	-	79	81.553	Aotus_nancymaae
ENSG00000145907	G3BP1	100	84.615	ENSACLG00000017400	g3bp1	98	66.119	Astatotilapia_calliptera
ENSG00000145907	G3BP1	100	82.906	ENSACLG00000022950	g3bp2	87	60.173	Astatotilapia_calliptera
ENSG00000145907	G3BP1	100	84.615	ENSAMXG00000010833	g3bp1	98	70.149	Astyanax_mexicanus
ENSG00000145907	G3BP1	100	82.906	ENSAMXG00000004459	zgc:56304	89	60.699	Astyanax_mexicanus
ENSG00000145907	G3BP1	100	100.000	ENSBTAG00000020309	G3BP1	100	96.567	Bos_taurus
ENSG00000145907	G3BP1	100	81.197	ENSBTAG00000014041	G3BP2	88	64.302	Bos_taurus
ENSG00000145907	G3BP1	100	81.197	ENSCJAG00000019897	G3BP2	88	64.073	Callithrix_jacchus
ENSG00000145907	G3BP1	100	100.000	ENSCJAG00000015407	G3BP1	100	99.356	Callithrix_jacchus
ENSG00000145907	G3BP1	100	96.226	ENSCJAG00000048700	-	88	89.394	Callithrix_jacchus
ENSG00000145907	G3BP1	100	100.000	ENSCAFG00000017841	G3BP1	99	97.936	Canis_familiaris
ENSG00000145907	G3BP1	100	81.197	ENSCAFG00000008371	G3BP2	87	64.384	Canis_familiaris
ENSG00000145907	G3BP1	100	81.197	ENSCAFG00020011645	G3BP2	88	64.384	Canis_lupus_dingo
ENSG00000145907	G3BP1	100	100.000	ENSCAFG00020023763	G3BP1	100	97.854	Canis_lupus_dingo
ENSG00000145907	G3BP1	100	100.000	ENSCHIG00000015936	G3BP1	100	96.352	Capra_hircus
ENSG00000145907	G3BP1	100	81.197	ENSCHIG00000013864	G3BP2	88	64.531	Capra_hircus
ENSG00000145907	G3BP1	100	100.000	ENSTSYG00000004570	G3BP1	100	97.854	Carlito_syrichta
ENSG00000145907	G3BP1	100	81.197	ENSTSYG00000011860	G3BP2	87	64.569	Carlito_syrichta
ENSG00000145907	G3BP1	100	99.145	ENSTSYG00000030090	-	90	94.000	Carlito_syrichta
ENSG00000145907	G3BP1	100	81.197	ENSCAPG00000007107	G3BP2	87	57.798	Cavia_aperea
ENSG00000145907	G3BP1	100	100.000	ENSCAPG00000000705	G3BP1	100	91.631	Cavia_aperea
ENSG00000145907	G3BP1	100	81.197	ENSCPOG00000012052	G3BP2	88	64.302	Cavia_porcellus
ENSG00000145907	G3BP1	100	100.000	ENSCPOG00000006626	G3BP1	100	96.352	Cavia_porcellus
ENSG00000145907	G3BP1	100	100.000	ENSCCAG00000028702	G3BP1	100	99.571	Cebus_capucinus
ENSG00000145907	G3BP1	100	75.214	ENSCCAG00000002779	-	87	59.441	Cebus_capucinus
ENSG00000145907	G3BP1	84	80.645	ENSCCAG00000030724	-	83	43.750	Cebus_capucinus
ENSG00000145907	G3BP1	100	81.197	ENSCCAG00000024593	-	88	64.073	Cebus_capucinus
ENSG00000145907	G3BP1	100	100.000	ENSCATG00000018373	G3BP1	100	99.356	Cercocebus_atys
ENSG00000145907	G3BP1	100	81.197	ENSCATG00000025521	G3BP2	88	64.073	Cercocebus_atys
ENSG00000145907	G3BP1	100	79.185	ENSCATG00000039913	-	100	79.185	Cercocebus_atys
ENSG00000145907	G3BP1	100	79.828	ENSCLAG00000012120	-	100	79.614	Chinchilla_lanigera
ENSG00000145907	G3BP1	100	100.000	ENSCLAG00000012636	-	100	97.854	Chinchilla_lanigera
ENSG00000145907	G3BP1	100	81.197	ENSCLAG00000003285	G3BP2	88	64.989	Chinchilla_lanigera
ENSG00000145907	G3BP1	100	100.000	ENSCSAG00000010876	G3BP1	100	99.571	Chlorocebus_sabaeus
ENSG00000145907	G3BP1	100	81.197	ENSCSAG00000004697	G3BP2	88	57.437	Chlorocebus_sabaeus
ENSG00000145907	G3BP1	100	81.197	ENSCHOG00000005346	G3BP2	88	63.158	Choloepus_hoffmanni
ENSG00000145907	G3BP1	73	100.000	ENSCHOG00000010802	-	70	100.000	Choloepus_hoffmanni
ENSG00000145907	G3BP1	100	83.761	ENSCPBG00000013475	G3BP2	84	65.675	Chrysemys_picta_bellii
ENSG00000145907	G3BP1	100	89.744	ENSCPBG00000010203	G3BP1	98	91.367	Chrysemys_picta_bellii
ENSG00000145907	G3BP1	100	64.957	ENSCING00000004760	-	91	41.124	Ciona_intestinalis
ENSG00000145907	G3BP1	100	67.521	ENSCSAVG00000008160	-	92	44.118	Ciona_savignyi
ENSG00000145907	G3BP1	97	81.858	ENSCANG00000043121	-	96	88.321	Colobus_angolensis_palliatus
ENSG00000145907	G3BP1	100	96.610	ENSCANG00000038945	-	100	95.931	Colobus_angolensis_palliatus
ENSG00000145907	G3BP1	100	88.034	ENSCANG00000034654	-	100	80.901	Colobus_angolensis_palliatus
ENSG00000145907	G3BP1	100	81.197	ENSCANG00000036407	G3BP2	88	64.073	Colobus_angolensis_palliatus
ENSG00000145907	G3BP1	100	83.761	ENSCGRG00001024004	-	100	82.655	Cricetulus_griseus_chok1gshd
ENSG00000145907	G3BP1	100	81.197	ENSCGRG00001017447	G3bp2	88	64.073	Cricetulus_griseus_chok1gshd
ENSG00000145907	G3BP1	100	86.325	ENSCGRG00001022279	-	100	84.582	Cricetulus_griseus_chok1gshd
ENSG00000145907	G3BP1	100	99.145	ENSCGRG00001015623	-	100	85.176	Cricetulus_griseus_chok1gshd
ENSG00000145907	G3BP1	100	83.761	ENSCGRG00000018066	-	100	82.227	Cricetulus_griseus_crigri
ENSG00000145907	G3BP1	100	99.145	ENSCGRG00000014158	-	100	91.221	Cricetulus_griseus_crigri
ENSG00000145907	G3BP1	100	81.197	ENSCGRG00000013721	G3bp2	88	64.073	Cricetulus_griseus_crigri
ENSG00000145907	G3BP1	100	83.761	ENSCSEG00000012777	g3bp1	98	62.195	Cynoglossus_semilaevis
ENSG00000145907	G3BP1	100	81.197	ENSCSEG00000009591	g3bp2	88	63.087	Cynoglossus_semilaevis
ENSG00000145907	G3BP1	100	82.051	ENSCVAG00000011014	g3bp2	88	63.182	Cyprinodon_variegatus
ENSG00000145907	G3BP1	100	83.761	ENSCVAG00000006194	g3bp1	89	64.334	Cyprinodon_variegatus
ENSG00000145907	G3BP1	100	83.761	ENSDARG00000017741	g3bp1	98	64.346	Danio_rerio
ENSG00000145907	G3BP1	100	84.615	ENSDARG00000074572	zgc:56304	92	84.173	Danio_rerio
ENSG00000145907	G3BP1	100	83.019	ENSDARG00000014790	g3bp2	87	60.532	Danio_rerio
ENSG00000145907	G3BP1	79	65.060	ENSDNOG00000040673	-	85	36.957	Dasypus_novemcinctus
ENSG00000145907	G3BP1	100	81.197	ENSDNOG00000045619	-	83	63.750	Dasypus_novemcinctus
ENSG00000145907	G3BP1	86	96.030	ENSDNOG00000018758	-	99	95.980	Dasypus_novemcinctus
ENSG00000145907	G3BP1	100	100.000	ENSDNOG00000045769	-	100	95.494	Dasypus_novemcinctus
ENSG00000145907	G3BP1	86	100.000	ENSDORG00000025959	G3bp1	100	84.829	Dipodomys_ordii
ENSG00000145907	G3BP1	100	81.197	ENSDORG00000028927	G3bp2	88	63.927	Dipodomys_ordii
ENSG00000145907	G3BP1	100	81.197	ENSETEG00000016219	G3BP2	88	62.785	Echinops_telfairi
ENSG00000145907	G3BP1	93	95.381	ENSETEG00000017447	G3BP1	99	95.381	Echinops_telfairi
ENSG00000145907	G3BP1	100	100.000	ENSEASG00005001232	G3BP1	100	97.854	Equus_asinus_asinus
ENSG00000145907	G3BP1	100	81.197	ENSEASG00005016513	G3BP2	88	63.844	Equus_asinus_asinus
ENSG00000145907	G3BP1	100	100.000	ENSECAG00000003368	G3BP1	97	97.854	Equus_caballus
ENSG00000145907	G3BP1	100	81.197	ENSECAG00000007917	G3BP2	88	64.073	Equus_caballus
ENSG00000145907	G3BP1	100	100.000	ENSEEUG00000012278	G3BP1	100	87.124	Erinaceus_europaeus
ENSG00000145907	G3BP1	100	81.197	ENSEEUG00000013436	G3BP2	88	59.954	Erinaceus_europaeus
ENSG00000145907	G3BP1	100	83.761	ENSELUG00000015665	g3bp2	87	63.146	Esox_lucius
ENSG00000145907	G3BP1	100	82.906	ENSELUG00000022200	g3bp1	98	64.463	Esox_lucius
ENSG00000145907	G3BP1	100	100.000	ENSFCAG00000006019	G3BP1	100	98.283	Felis_catus
ENSG00000145907	G3BP1	100	81.197	ENSFCAG00000025114	G3BP2	88	64.612	Felis_catus
ENSG00000145907	G3BP1	100	83.761	ENSFALG00000008198	G3BP2	87	67.366	Ficedula_albicollis
ENSG00000145907	G3BP1	100	89.744	ENSFALG00000008253	G3BP1	100	84.177	Ficedula_albicollis
ENSG00000145907	G3BP1	100	100.000	ENSFDAG00000012773	G3BP1	100	97.639	Fukomys_damarensis
ENSG00000145907	G3BP1	94	69.091	ENSFDAG00000015575	-	85	48.456	Fukomys_damarensis
ENSG00000145907	G3BP1	100	81.197	ENSFDAG00000012747	-	88	64.073	Fukomys_damarensis
ENSG00000145907	G3BP1	100	82.051	ENSFHEG00000018770	g3bp2	88	63.864	Fundulus_heteroclitus
ENSG00000145907	G3BP1	100	84.615	ENSFHEG00000014921	g3bp1	90	66.742	Fundulus_heteroclitus
ENSG00000145907	G3BP1	100	82.906	ENSGMOG00000016319	g3bp2	87	65.541	Gadus_morhua
ENSG00000145907	G3BP1	100	82.906	ENSGMOG00000019345	g3bp1	96	65.848	Gadus_morhua
ENSG00000145907	G3BP1	100	89.744	ENSGALG00000004160	G3BP1	100	84.177	Gallus_gallus
ENSG00000145907	G3BP1	100	83.761	ENSGALG00000010882	G3BP2	88	66.819	Gallus_gallus
ENSG00000145907	G3BP1	100	82.051	ENSGAFG00000016593	g3bp2	88	64.091	Gambusia_affinis
ENSG00000145907	G3BP1	100	83.761	ENSGAFG00000019826	g3bp1	89	65.138	Gambusia_affinis
ENSG00000145907	G3BP1	100	82.906	ENSGACG00000017342	g3bp2	88	63.677	Gasterosteus_aculeatus
ENSG00000145907	G3BP1	100	82.906	ENSGACG00000016848	g3bp1	98	63.768	Gasterosteus_aculeatus
ENSG00000145907	G3BP1	100	89.744	ENSGAGG00000013372	G3BP1	100	85.439	Gopherus_agassizii
ENSG00000145907	G3BP1	100	83.761	ENSGAGG00000017925	G3BP2	88	65.904	Gopherus_agassizii
ENSG00000145907	G3BP1	100	70.940	ENSGGOG00000023113	-	100	66.667	Gorilla_gorilla
ENSG00000145907	G3BP1	100	81.197	ENSGGOG00000014947	G3BP2	88	64.073	Gorilla_gorilla
ENSG00000145907	G3BP1	100	100.000	ENSGGOG00000022952	G3BP1	100	100.000	Gorilla_gorilla
ENSG00000145907	G3BP1	100	82.906	ENSHBUG00000007387	g3bp2	87	63.326	Haplochromis_burtoni
ENSG00000145907	G3BP1	100	84.615	ENSHBUG00000011664	g3bp1	98	65.510	Haplochromis_burtoni
ENSG00000145907	G3BP1	100	81.197	ENSHGLG00000012655	G3BP2	88	64.073	Heterocephalus_glaber_female
ENSG00000145907	G3BP1	100	100.000	ENSHGLG00000014921	G3BP1	100	97.425	Heterocephalus_glaber_female
ENSG00000145907	G3BP1	100	81.197	ENSHGLG00100017913	G3BP2	88	64.073	Heterocephalus_glaber_male
ENSG00000145907	G3BP1	100	95.096	ENSHGLG00100011650	G3BP1	100	95.096	Heterocephalus_glaber_male
ENSG00000145907	G3BP1	100	82.051	ENSHCOG00000004888	g3bp2	88	59.783	Hippocampus_comes
ENSG00000145907	G3BP1	100	81.197	ENSHCOG00000003474	g3bp1	89	65.463	Hippocampus_comes
ENSG00000145907	G3BP1	100	84.615	ENSIPUG00000001190	G3BP	89	66.197	Ictalurus_punctatus
ENSG00000145907	G3BP1	100	84.615	ENSIPUG00000003561	g3bp2	89	59.780	Ictalurus_punctatus
ENSG00000145907	G3BP1	100	81.197	ENSSTOG00000012975	G3BP2	88	63.844	Ictidomys_tridecemlineatus
ENSG00000145907	G3BP1	100	100.000	ENSSTOG00000015928	-	100	98.069	Ictidomys_tridecemlineatus
ENSG00000145907	G3BP1	100	85.470	ENSSTOG00000031229	-	84	72.906	Ictidomys_tridecemlineatus
ENSG00000145907	G3BP1	100	81.197	ENSJJAG00000016557	G3bp2	88	65.217	Jaculus_jaculus
ENSG00000145907	G3BP1	100	100.000	ENSJJAG00000017035	G3bp1	100	95.279	Jaculus_jaculus
ENSG00000145907	G3BP1	100	82.906	ENSKMAG00000002648	g3bp2	87	59.867	Kryptolebias_marmoratus
ENSG00000145907	G3BP1	100	83.761	ENSKMAG00000002530	g3bp1	98	64.155	Kryptolebias_marmoratus
ENSG00000145907	G3BP1	100	82.051	ENSLBEG00000012867	g3bp1	96	67.873	Labrus_bergylta
ENSG00000145907	G3BP1	100	82.051	ENSLBEG00000016487	g3bp2	86	62.385	Labrus_bergylta
ENSG00000145907	G3BP1	94	52.018	ENSLBEG00000005270	-	98	51.528	Labrus_bergylta
ENSG00000145907	G3BP1	100	88.889	ENSLACG00000017962	G3BP1	100	61.992	Latimeria_chalumnae
ENSG00000145907	G3BP1	100	85.470	ENSLACG00000002985	G3BP2	88	68.650	Latimeria_chalumnae
ENSG00000145907	G3BP1	100	88.889	ENSLOCG00000011657	g3bp1	97	71.734	Lepisosteus_oculatus
ENSG00000145907	G3BP1	86	93.750	ENSLOCG00000013470	g3bp2	89	62.009	Lepisosteus_oculatus
ENSG00000145907	G3BP1	100	100.000	ENSLAFG00000009182	G3BP1	100	97.210	Loxodonta_africana
ENSG00000145907	G3BP1	100	81.197	ENSLAFG00000023321	G3BP2	87	64.302	Loxodonta_africana
ENSG00000145907	G3BP1	100	76.923	ENSMFAG00000033595	-	100	71.030	Macaca_fascicularis
ENSG00000145907	G3BP1	100	81.197	ENSMFAG00000044717	G3BP2	88	64.073	Macaca_fascicularis
ENSG00000145907	G3BP1	100	100.000	ENSMFAG00000036965	G3BP1	100	99.571	Macaca_fascicularis
ENSG00000145907	G3BP1	100	81.197	ENSMMUG00000043525	G3BP2	93	44.118	Macaca_mulatta
ENSG00000145907	G3BP1	100	100.000	ENSMMUG00000014701	G3BP1	100	98.039	Macaca_mulatta
ENSG00000145907	G3BP1	100	83.761	ENSMMUG00000022912	-	100	77.039	Macaca_mulatta
ENSG00000145907	G3BP1	100	100.000	ENSMNEG00000021253	G3BP1	100	99.571	Macaca_nemestrina
ENSG00000145907	G3BP1	100	76.923	ENSMNEG00000042994	-	100	75.536	Macaca_nemestrina
ENSG00000145907	G3BP1	100	81.197	ENSMNEG00000045171	G3BP2	88	64.073	Macaca_nemestrina
ENSG00000145907	G3BP1	94	99.087	ENSMLEG00000032036	G3BP1	100	99.087	Mandrillus_leucophaeus
ENSG00000145907	G3BP1	100	81.197	ENSMLEG00000027756	G3BP2	88	64.073	Mandrillus_leucophaeus
ENSG00000145907	G3BP1	98	83.682	ENSMLEG00000032050	-	100	81.250	Mandrillus_leucophaeus
ENSG00000145907	G3BP1	100	84.615	ENSMAMG00000013109	g3bp1	98	65.984	Mastacembelus_armatus
ENSG00000145907	G3BP1	100	82.906	ENSMAMG00000015188	g3bp2	86	63.554	Mastacembelus_armatus
ENSG00000145907	G3BP1	100	84.615	ENSMZEG00005020372	g3bp1	98	65.714	Maylandia_zebra
ENSG00000145907	G3BP1	100	82.906	ENSMZEG00005019412	g3bp2	87	60.173	Maylandia_zebra
ENSG00000145907	G3BP1	100	81.667	ENSMGAG00000007221	G3BP2	87	66.364	Meleagris_gallopavo
ENSG00000145907	G3BP1	86	96.875	ENSMGAG00000005963	G3BP1	100	82.651	Meleagris_gallopavo
ENSG00000145907	G3BP1	100	99.145	ENSMAUG00000008655	G3bp1	100	92.719	Mesocricetus_auratus
ENSG00000145907	G3BP1	100	81.197	ENSMAUG00000008136	G3bp2	88	64.073	Mesocricetus_auratus
ENSG00000145907	G3BP1	100	81.197	ENSMICG00000007795	G3BP2	88	65.446	Microcebus_murinus
ENSG00000145907	G3BP1	86	100.000	ENSMICG00000030041	-	93	78.082	Microcebus_murinus
ENSG00000145907	G3BP1	100	89.270	ENSMICG00000033153	-	100	89.270	Microcebus_murinus
ENSG00000145907	G3BP1	100	92.340	ENSMICG00000012235	-	100	92.340	Microcebus_murinus
ENSG00000145907	G3BP1	100	99.145	ENSMOCG00000005709	G3bp1	100	92.505	Microtus_ochrogaster
ENSG00000145907	G3BP1	100	81.197	ENSMOCG00000020007	G3bp2	88	64.989	Microtus_ochrogaster
ENSG00000145907	G3BP1	100	82.051	ENSMMOG00000005859	g3bp2	87	61.556	Mola_mola
ENSG00000145907	G3BP1	100	82.906	ENSMMOG00000000755	g3bp1	96	62.937	Mola_mola
ENSG00000145907	G3BP1	100	99.145	ENSMODG00000008993	-	99	89.079	Monodelphis_domestica
ENSG00000145907	G3BP1	100	80.342	ENSMODG00000019205	G3BP2	87	63.616	Monodelphis_domestica
ENSG00000145907	G3BP1	100	87.619	ENSMODG00000023523	-	99	77.371	Monodelphis_domestica
ENSG00000145907	G3BP1	100	99.145	ENSMODG00000013903	-	98	87.234	Monodelphis_domestica
ENSG00000145907	G3BP1	100	83.761	ENSMALG00000002804	g3bp1	98	65.235	Monopterus_albus
ENSG00000145907	G3BP1	100	83.761	ENSMALG00000000817	g3bp2	84	83.193	Monopterus_albus
ENSG00000145907	G3BP1	100	81.197	MGP_CAROLIEiJ_G0027408	G3bp2	100	81.955	Mus_caroli
ENSG00000145907	G3BP1	100	81.197	ENSMUSG00000029405	G3bp2	100	81.955	Mus_musculus
ENSG00000145907	G3BP1	100	99.145	ENSMUSG00000018583	G3bp1	100	93.362	Mus_musculus
ENSG00000145907	G3BP1	100	81.197	MGP_PahariEiJ_G0017186	G3bp2	100	81.955	Mus_pahari
ENSG00000145907	G3BP1	100	98.291	MGP_PahariEiJ_G0017509	G3bp1	100	92.934	Mus_pahari
ENSG00000145907	G3BP1	100	81.197	MGP_SPRETEiJ_G0028405	G3bp2	100	81.955	Mus_spretus
ENSG00000145907	G3BP1	100	100.000	ENSMPUG00000013661	G3BP1	100	97.425	Mustela_putorius_furo
ENSG00000145907	G3BP1	100	80.342	ENSMPUG00000009042	G3BP2	84	64.384	Mustela_putorius_furo
ENSG00000145907	G3BP1	100	100.000	ENSMLUG00000001581	G3BP1	100	96.146	Myotis_lucifugus
ENSG00000145907	G3BP1	100	81.197	ENSMLUG00000004753	G3BP2	88	59.497	Myotis_lucifugus
ENSG00000145907	G3BP1	86	90.625	ENSNGAG00000014406	G3bp2	87	56.621	Nannospalax_galili
ENSG00000145907	G3BP1	100	100.000	ENSNGAG00000010742	G3bp1	100	94.850	Nannospalax_galili
ENSG00000145907	G3BP1	100	100.000	ENSNGAG00000023431	-	70	98.387	Nannospalax_galili
ENSG00000145907	G3BP1	100	82.906	ENSNBRG00000011881	g3bp2	87	63.326	Neolamprologus_brichardi
ENSG00000145907	G3BP1	100	84.615	ENSNBRG00000014110	g3bp1	98	65.918	Neolamprologus_brichardi
ENSG00000145907	G3BP1	100	81.197	ENSNLEG00000007996	G3BP2	88	63.927	Nomascus_leucogenys
ENSG00000145907	G3BP1	100	100.000	ENSNLEG00000027246	G3BP1	100	98.693	Nomascus_leucogenys
ENSG00000145907	G3BP1	100	87.736	ENSNLEG00000030245	-	98	87.234	Nomascus_leucogenys
ENSG00000145907	G3BP1	100	80.342	ENSMEUG00000004126	G3BP2	90	63.844	Notamacropus_eugenii
ENSG00000145907	G3BP1	100	100.000	ENSOPRG00000010562	G3BP1	100	89.056	Ochotona_princeps
ENSG00000145907	G3BP1	72	79.245	ENSOPRG00000006307	G3BP2	88	61.728	Ochotona_princeps
ENSG00000145907	G3BP1	100	92.308	ENSODEG00000016266	-	100	90.343	Octodon_degus
ENSG00000145907	G3BP1	100	76.068	ENSODEG00000001719	-	96	52.914	Octodon_degus
ENSG00000145907	G3BP1	93	85.321	ENSODEG00000004103	-	99	66.812	Octodon_degus
ENSG00000145907	G3BP1	100	78.112	ENSODEG00000011464	-	100	78.326	Octodon_degus
ENSG00000145907	G3BP1	97	89.216	ENSODEG00000018116	-	99	79.015	Octodon_degus
ENSG00000145907	G3BP1	100	82.051	ENSODEG00000006601	-	100	82.707	Octodon_degus
ENSG00000145907	G3BP1	93	97.005	ENSODEG00000008869	-	100	97.005	Octodon_degus
ENSG00000145907	G3BP1	100	82.051	ENSONIG00000017454	g3bp2	85	63.326	Oreochromis_niloticus
ENSG00000145907	G3BP1	100	84.615	ENSONIG00000004263	g3bp1	98	64.694	Oreochromis_niloticus
ENSG00000145907	G3BP1	84	93.548	ENSOANG00000006922	-	82	58.621	Ornithorhynchus_anatinus
ENSG00000145907	G3BP1	100	91.453	ENSOANG00000005110	-	98	85.837	Ornithorhynchus_anatinus
ENSG00000145907	G3BP1	100	100.000	ENSOCUG00000022069	-	100	92.918	Oryctolagus_cuniculus
ENSG00000145907	G3BP1	100	100.000	ENSOCUG00000022143	-	100	86.724	Oryctolagus_cuniculus
ENSG00000145907	G3BP1	100	81.197	ENSOCUG00000003262	G3BP2	88	64.073	Oryctolagus_cuniculus
ENSG00000145907	G3BP1	100	82.906	ENSORLG00000026412	g3bp2	88	63.029	Oryzias_latipes
ENSG00000145907	G3BP1	100	81.197	ENSORLG00000011422	g3bp1	98	62.552	Oryzias_latipes
ENSG00000145907	G3BP1	100	82.906	ENSORLG00020019305	g3bp2	88	60.470	Oryzias_latipes_hni
ENSG00000145907	G3BP1	100	81.197	ENSORLG00020016606	g3bp1	98	62.241	Oryzias_latipes_hni
ENSG00000145907	G3BP1	100	82.906	ENSORLG00015019301	g3bp2	80	63.029	Oryzias_latipes_hsok
ENSG00000145907	G3BP1	100	81.197	ENSORLG00015011313	g3bp1	98	62.241	Oryzias_latipes_hsok
ENSG00000145907	G3BP1	100	82.906	ENSOMEG00000004775	g3bp2	88	63.029	Oryzias_melastigma
ENSG00000145907	G3BP1	100	81.197	ENSOMEG00000021702	g3bp1	98	61.191	Oryzias_melastigma
ENSG00000145907	G3BP1	100	81.197	ENSOGAG00000000157	G3BP2	88	57.437	Otolemur_garnettii
ENSG00000145907	G3BP1	100	83.761	ENSOGAG00000025677	-	100	80.260	Otolemur_garnettii
ENSG00000145907	G3BP1	100	91.509	ENSOGAG00000029258	-	99	85.498	Otolemur_garnettii
ENSG00000145907	G3BP1	100	100.000	ENSOGAG00000001726	-	100	96.815	Otolemur_garnettii
ENSG00000145907	G3BP1	100	100.000	ENSOARG00000009135	G3BP1	99	94.581	Ovis_aries
ENSG00000145907	G3BP1	100	81.197	ENSOARG00000015652	G3BP2	87	64.531	Ovis_aries
ENSG00000145907	G3BP1	100	81.197	ENSPPAG00000042327	G3BP2	92	64.073	Pan_paniscus
ENSG00000145907	G3BP1	100	81.197	ENSPPAG00000039991	-	100	73.820	Pan_paniscus
ENSG00000145907	G3BP1	100	100.000	ENSPPAG00000027573	G3BP1	100	100.000	Pan_paniscus
ENSG00000145907	G3BP1	100	100.000	ENSPPRG00000002960	G3BP1	100	98.069	Panthera_pardus
ENSG00000145907	G3BP1	100	81.197	ENSPPRG00000009339	G3BP2	88	64.612	Panthera_pardus
ENSG00000145907	G3BP1	100	99.145	ENSPTIG00000013868	G3BP1	100	98.069	Panthera_tigris_altaica
ENSG00000145907	G3BP1	100	81.197	ENSPTIG00000019304	G3BP2	88	61.591	Panthera_tigris_altaica
ENSG00000145907	G3BP1	100	80.342	ENSPTRG00000046031	-	100	73.820	Pan_troglodytes
ENSG00000145907	G3BP1	100	81.197	ENSPTRG00000016175	G3BP2	88	64.073	Pan_troglodytes
ENSG00000145907	G3BP1	100	100.000	ENSPTRG00000017438	G3BP1	100	99.785	Pan_troglodytes
ENSG00000145907	G3BP1	100	100.000	ENSPANG00000017662	G3BP1	100	95.064	Papio_anubis
ENSG00000145907	G3BP1	100	77.778	ENSPANG00000007104	-	90	78.638	Papio_anubis
ENSG00000145907	G3BP1	100	81.197	ENSPANG00000020312	G3BP2	88	64.073	Papio_anubis
ENSG00000145907	G3BP1	100	82.906	ENSPKIG00000022556	g3bp1	98	65.546	Paramormyrops_kingsleyae
ENSG00000145907	G3BP1	100	82.906	ENSPKIG00000013985	g3bp2	87	64.733	Paramormyrops_kingsleyae
ENSG00000145907	G3BP1	100	83.019	ENSPKIG00000013310	-	87	63.111	Paramormyrops_kingsleyae
ENSG00000145907	G3BP1	100	89.744	ENSPSIG00000015000	G3BP1	100	85.021	Pelodiscus_sinensis
ENSG00000145907	G3BP1	100	83.761	ENSPSIG00000007933	G3BP2	87	65.675	Pelodiscus_sinensis
ENSG00000145907	G3BP1	100	82.051	ENSPMGG00000001290	g3bp1	89	57.512	Periophthalmus_magnuspinnatus
ENSG00000145907	G3BP1	100	82.906	ENSPMGG00000001883	g3bp2	88	64.494	Periophthalmus_magnuspinnatus
ENSG00000145907	G3BP1	100	81.197	ENSPEMG00000017864	-	100	81.955	Peromyscus_maniculatus_bairdii
ENSG00000145907	G3BP1	100	99.145	ENSPEMG00000020531	G3bp1	100	93.362	Peromyscus_maniculatus_bairdii
ENSG00000145907	G3BP1	100	50.427	ENSPMAG00000005131	-	91	55.797	Petromyzon_marinus
ENSG00000145907	G3BP1	100	81.197	ENSPMAG00000009860	g3bp1	64	82.609	Petromyzon_marinus
ENSG00000145907	G3BP1	100	99.145	ENSPCIG00000010359	G3BP1	100	88.161	Phascolarctos_cinereus
ENSG00000145907	G3BP1	100	80.342	ENSPCIG00000007044	G3BP2	88	64.302	Phascolarctos_cinereus
ENSG00000145907	G3BP1	100	83.761	ENSPFOG00000007942	g3bp1	88	66.364	Poecilia_formosa
ENSG00000145907	G3BP1	100	82.051	ENSPFOG00000004671	g3bp2	88	61.087	Poecilia_formosa
ENSG00000145907	G3BP1	100	82.051	ENSPLAG00000001201	g3bp2	88	63.636	Poecilia_latipinna
ENSG00000145907	G3BP1	100	83.761	ENSPLAG00000009678	g3bp1	89	66.364	Poecilia_latipinna
ENSG00000145907	G3BP1	100	82.051	ENSPMEG00000015177	g3bp2	88	63.636	Poecilia_mexicana
ENSG00000145907	G3BP1	100	83.761	ENSPMEG00000012942	g3bp1	89	66.136	Poecilia_mexicana
ENSG00000145907	G3BP1	100	82.051	ENSPREG00000001772	g3bp2	88	61.707	Poecilia_reticulata
ENSG00000145907	G3BP1	100	83.761	ENSPREG00000008376	g3bp1	89	66.136	Poecilia_reticulata
ENSG00000145907	G3BP1	100	81.197	ENSPPYG00000014846	G3BP2	88	64.073	Pongo_abelii
ENSG00000145907	G3BP1	100	100.000	ENSPPYG00000015968	G3BP1	100	99.785	Pongo_abelii
ENSG00000145907	G3BP1	72	79.245	ENSPCAG00000015109	G3BP2	88	62.376	Procavia_capensis
ENSG00000145907	G3BP1	100	81.197	ENSPCOG00000015114	G3BP2	88	64.073	Propithecus_coquereli
ENSG00000145907	G3BP1	100	96.391	ENSPVAG00000017250	G3BP1	100	96.391	Pteropus_vampyrus
ENSG00000145907	G3BP1	100	81.197	ENSPVAG00000010166	G3BP2	88	60.230	Pteropus_vampyrus
ENSG00000145907	G3BP1	100	82.906	ENSPNYG00000010813	g3bp2	87	63.326	Pundamilia_nyererei
ENSG00000145907	G3BP1	100	84.615	ENSPNYG00000003109	g3bp1	98	64.358	Pundamilia_nyererei
ENSG00000145907	G3BP1	100	82.906	ENSPNAG00000021170	zgc:56304	89	62.585	Pygocentrus_nattereri
ENSG00000145907	G3BP1	100	84.615	ENSPNAG00000024583	g3bp1	100	69.198	Pygocentrus_nattereri
ENSG00000145907	G3BP1	100	81.197	ENSRNOG00000002433	G3bp2	88	56.751	Rattus_norvegicus
ENSG00000145907	G3BP1	100	90.598	ENSRNOG00000032820	AABR07061614.1	100	75.589	Rattus_norvegicus
ENSG00000145907	G3BP1	100	99.145	ENSRNOG00000013186	G3bp1	100	93.362	Rattus_norvegicus
ENSG00000145907	G3BP1	100	87.736	ENSRBIG00000028792	-	100	80.469	Rhinopithecus_bieti
ENSG00000145907	G3BP1	100	81.197	ENSRBIG00000042968	G3BP2	88	64.073	Rhinopithecus_bieti
ENSG00000145907	G3BP1	100	100.000	ENSRBIG00000042268	G3BP1	100	99.571	Rhinopithecus_bieti
ENSG00000145907	G3BP1	100	87.736	ENSRROG00000045035	-	100	87.662	Rhinopithecus_roxellana
ENSG00000145907	G3BP1	100	100.000	ENSRROG00000030118	G3BP1	100	99.571	Rhinopithecus_roxellana
ENSG00000145907	G3BP1	100	81.197	ENSRROG00000040979	G3BP2	88	64.073	Rhinopithecus_roxellana
ENSG00000145907	G3BP1	96	41.401	ENSSBOG00000027791	-	83	39.524	Saimiri_boliviensis_boliviensis
ENSG00000145907	G3BP1	73	100.000	ENSSBOG00000029969	G3BP1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000145907	G3BP1	100	81.197	ENSSBOG00000023693	-	88	64.073	Saimiri_boliviensis_boliviensis
ENSG00000145907	G3BP1	100	99.145	ENSSHAG00000008357	G3BP1	100	89.507	Sarcophilus_harrisii
ENSG00000145907	G3BP1	100	80.342	ENSSHAG00000007414	G3BP2	87	63.158	Sarcophilus_harrisii
ENSG00000145907	G3BP1	100	84.615	ENSSFOG00015017846	-	87	62.889	Scleropages_formosus
ENSG00000145907	G3BP1	100	83.019	ENSSFOG00015001993	g3bp1	97	64.208	Scleropages_formosus
ENSG00000145907	G3BP1	100	83.761	ENSSFOG00015013690	zgc:56304	91	64.884	Scleropages_formosus
ENSG00000145907	G3BP1	100	83.761	ENSSMAG00000006669	g3bp1	98	64.959	Scophthalmus_maximus
ENSG00000145907	G3BP1	100	82.906	ENSSMAG00000005956	g3bp2	88	60.944	Scophthalmus_maximus
ENSG00000145907	G3BP1	100	83.761	ENSSDUG00000008796	g3bp1	98	66.119	Seriola_dumerili
ENSG00000145907	G3BP1	100	82.906	ENSSDUG00000008013	g3bp2	86	64.252	Seriola_dumerili
ENSG00000145907	G3BP1	100	83.761	ENSSLDG00000014124	g3bp1	98	61.336	Seriola_lalandi_dorsalis
ENSG00000145907	G3BP1	100	82.906	ENSSLDG00000022714	g3bp2	86	66.125	Seriola_lalandi_dorsalis
ENSG00000145907	G3BP1	72	79.245	ENSSARG00000009503	G3BP2	88	61.975	Sorex_araneus
ENSG00000145907	G3BP1	100	83.761	ENSSPUG00000008986	G3BP2	87	66.200	Sphenodon_punctatus
ENSG00000145907	G3BP1	100	91.453	ENSSPUG00000004389	G3BP1	100	82.278	Sphenodon_punctatus
ENSG00000145907	G3BP1	100	83.761	ENSSPAG00000014125	g3bp1	98	65.657	Stegastes_partitus
ENSG00000145907	G3BP1	100	82.906	ENSSPAG00000009800	g3bp2	86	63.554	Stegastes_partitus
ENSG00000145907	G3BP1	100	99.145	ENSSSCG00000035676	G3BP1	100	96.567	Sus_scrofa
ENSG00000145907	G3BP1	100	81.197	ENSSSCG00000022940	G3BP2	88	64.450	Sus_scrofa
ENSG00000145907	G3BP1	100	83.761	ENSTGUG00000001561	G3BP2	87	67.133	Taeniopygia_guttata
ENSG00000145907	G3BP1	100	89.744	ENSTGUG00000000753	G3BP1	100	86.081	Taeniopygia_guttata
ENSG00000145907	G3BP1	100	82.906	ENSTRUG00000024045	-	79	72.109	Takifugu_rubripes
ENSG00000145907	G3BP1	100	84.615	ENSTRUG00000011405	g3bp2	88	61.304	Takifugu_rubripes
ENSG00000145907	G3BP1	86	93.750	ENSTNIG00000011044	g3bp2	86	55.682	Tetraodon_nigroviridis
ENSG00000145907	G3BP1	100	82.906	ENSTNIG00000012954	g3bp1	99	63.278	Tetraodon_nigroviridis
ENSG00000145907	G3BP1	100	81.197	ENSTBEG00000008258	-	87	56.651	Tupaia_belangeri
ENSG00000145907	G3BP1	72	79.245	ENSTBEG00000012323	-	88	62.222	Tupaia_belangeri
ENSG00000145907	G3BP1	75	95.702	ENSTBEG00000004386	G3BP1	100	95.702	Tupaia_belangeri
ENSG00000145907	G3BP1	100	81.197	ENSTTRG00000013795	G3BP2	88	64.155	Tursiops_truncatus
ENSG00000145907	G3BP1	100	100.000	ENSTTRG00000009072	G3BP1	100	89.914	Tursiops_truncatus
ENSG00000145907	G3BP1	100	100.000	ENSUAMG00000008140	G3BP1	100	97.854	Ursus_americanus
ENSG00000145907	G3BP1	100	81.197	ENSUAMG00000017625	G3BP2	88	64.612	Ursus_americanus
ENSG00000145907	G3BP1	88	97.549	ENSUMAG00000003295	G3BP1	87	97.549	Ursus_maritimus
ENSG00000145907	G3BP1	100	81.197	ENSUMAG00000006774	G3BP2	88	64.840	Ursus_maritimus
ENSG00000145907	G3BP1	100	100.000	ENSVPAG00000004461	G3BP1	100	96.781	Vicugna_pacos
ENSG00000145907	G3BP1	100	81.197	ENSVPAG00000010710	G3BP2	88	59.039	Vicugna_pacos
ENSG00000145907	G3BP1	100	99.145	ENSVVUG00000007591	-	99	94.667	Vulpes_vulpes
ENSG00000145907	G3BP1	100	98.291	ENSVVUG00000015532	-	95	97.917	Vulpes_vulpes
ENSG00000145907	G3BP1	100	100.000	ENSVVUG00000005396	G3BP1	100	97.854	Vulpes_vulpes
ENSG00000145907	G3BP1	100	81.197	ENSVVUG00000024171	G3BP2	88	64.384	Vulpes_vulpes
ENSG00000145907	G3BP1	100	87.179	ENSXETG00000010712	g3bp1	100	77.053	Xenopus_tropicalis
ENSG00000145907	G3BP1	100	82.353	ENSXETG00000000334	g3bp2	88	63.431	Xenopus_tropicalis
ENSG00000145907	G3BP1	100	82.051	ENSXCOG00000015623	g3bp1	88	83.453	Xiphophorus_couchianus
ENSG00000145907	G3BP1	100	82.051	ENSXMAG00000010011	g3bp2	88	63.636	Xiphophorus_maculatus
ENSG00000145907	G3BP1	100	83.761	ENSXMAG00000019255	g3bp1	89	64.091	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0004003	ATP-dependent DNA helicase activity	9889278.	TAS	Function
GO:0004004	ATP-dependent RNA helicase activity	9889278.	TAS	Function
GO:0004519	endonuclease activity	-	IEA	Function
GO:0005515	protein binding	8649363.19615732.20180778.20643132.21455491.23209657.23953116.25225333.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	20180778.	IDA	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0007265	Ras protein signal transduction	8649363.	TAS	Process
GO:0010494	cytoplasmic stress granule	-	ISS	Component
GO:0032508	DNA duplex unwinding	-	IEA	Process
GO:0034063	stress granule assembly	20180778.23163895.	IMP	Process
GO:0043204	perikaryon	-	IEA	Component
GO:0090090	negative regulation of canonical Wnt signaling pathway	-	IEA	Process
GO:0090305	nucleic acid phosphodiester bond hydrolysis	-	IEA	Process
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25800057	YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1.	J Cell Biol	2015 Mar 30	Somasekharan SP	doi: 10.1083/jcb.201411047
17297477	Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP).	Oncogene	2007 Jun 21	Kim MM	-
25962958	Involvement of Ras GTPase-activating protein SH3 domain-binding protein 1 in the epithelial-to-mesenchymal transition-induced metastasis of breast cancer cells via the Smad signaling pathway.	Oncotarget	2015 Jul 10	Zhang H	-
25809930	Overexpression of Ras-GTPase-activating protein SH3 domain-binding protein 1 correlates with poor prognosis in gastric cancer patients.	Histopathology	2015 Nov	Min L	doi: 10.1111/his.12695
20663914	Human G3BP1 interacts with beta-F1-ATPase mRNA and inhibits its translation.	J Cell Sci	2010 Aug 15	Ortega AD	doi: 10.1242/jcs.065920
24321297	Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells.	Mol Cancer	2013 Dec 9	Winslow S	doi: 10.1186/1476-4598-12-156.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr5	151790343	Missense_Mutation	NA	S39F	0.08
BLCA	chr5	151800260	Frame_Shift_Ins	novel	*R335Gfs2**	0.45
BLCA	chr5	151800291	Silent	NA	F343F	0.34
BRCA	chr5	151799245	Missense_Mutation	NA	L259V	0.2
BRCA	chr5	151786594	5'UTR	novel		0.08
BRCA	chr5	151799910	Missense_Mutation	NA	E289K	0.08
BRCA	chr5	151804081	Missense_Mutation	NA	P464L	0.14
BRCA	chr5	151800343	Nonsense_Mutation	novel	Q361*	0.16	NTF2
BRCA	chr5	151800271	Missense_Mutation	novel	P337T	0.1
BRCA	chr5	151795496	Missense_Mutation	novel	E154Q	0.04
BRCA	chr5	151799946	Missense_Mutation	NA	Q301E	0.13
CESC	chr5	151791208	Intron	novel		0.29
COAD	chr5	151799965	Missense_Mutation	rs775783436	R307Q	0.27
COAD	chr5	151794192	Missense_Mutation	novel	D129Y	0.05
COAD	chr5	151799932	Missense_Mutation	NA	R296I	0.31
COAD	chr5	151791183	Intron	novel		0.16
COAD	chr5	151790944	Missense_Mutation	rs370340219	R78H	0.35
COAD	chr5	151790966	Silent	rs200897287	T85T	0.29
COAD	chr5	151803970	Missense_Mutation	novel	R427H	0.34
COAD	chr5	151786621	Translation_Start_Site	NA	M1?	0.26
COAD	chr5	151791055	Missense_Mutation	NA	A115V	0.41
COAD	chr5	151804083	Missense_Mutation	rs372751446	R465W	0.37
COAD	chr5	151786594	5'UTR	novel		0.1
COAD	chr5	151800784	Missense_Mutation	rs765135383	R370H	0.49	NTF2
COAD	chr5	151795499	Missense_Mutation	NA	E155K	0.19
COAD	chr5	151800001	Splice_Site	NA	X319_splice	0.14
COAD	chr5	151794175	Missense_Mutation	NA	K123T	0.32
COAD	chr5	151804029	Missense_Mutation	rs187250945	R447C	0.41
COAD	chr5	151800763	Missense_Mutation	novel	Y363C	0.32	NTF2
COAD	chr5	151795524	Missense_Mutation	novel	P163H	0.31
COAD	chr5	151786595	5'UTR	novel		0.29
COAD	chr5	151786638	Silent	novel	P6P	0.06
COAD	chr5	151790335	Missense_Mutation	NA	K36N	0.19
COAD	chr5	151804029	Missense_Mutation	rs187250945	R447C	0.15
COAD	chr5	151790395	Silent	rs373179919	Y56Y	0.13
ESCA	chr5	151803960	Nonsense_Mutation	novel	R424*	0.34
GBM	chr5	151790989	Missense_Mutation	NA	Q93R	0.4
GBM	chr5	151800782	Missense_Mutation	NA	L369F	0.28	NTF2
GBM	chr5	151799965	Missense_Mutation	rs775783436	R307Q	0.14
GBM	chr5	151797315	Missense_Mutation	novel	I210L	0.4
HNSC	chr5	151800346	Missense_Mutation	novel	S362G	0.48	NTF2
HNSC	chr5	151800335	Missense_Mutation	novel	D358V	0.26	NTF2
HNSC	chr5	151790367	Nonsense_Mutation	novel	S47*	0.17
HNSC	chr5	151804153	3'UTR	novel		0.53
KIRC	chr5	151786596	5'UTR	novel		0.26
KIRC	chr5	151786678	Missense_Mutation	NA	Y20H	0.32
KIRC	chr5	151803957	Nonsense_Mutation	rs140218237	R423*	0.35
KIRC	chr5	151804055	Frame_Shift_Ins	novel	*G457Wfs52**	0.22
KIRC	chr5	151799989	Missense_Mutation	NA	G315E	0.35
KIRC	chr5	151786684	Silent	NA	L22L	0.3
LGG	chr5	151800312	Silent	novel	E350E	0.07
LUAD	chr5	151791094	Intron	novel		0.21
LUAD	chr5	151794159	Missense_Mutation	NA	G118W	0.07
LUAD	chr5	151786672	Nonsense_Mutation	NA	Q18*	0.71
LUAD	chr5	151786651	Missense_Mutation	NA	V11F	0.14
LUAD	chr5	151794195	Missense_Mutation	NA	I130V	0.23
LUAD	chr5	151804032	Missense_Mutation	NA	G448R	0.07
LUAD	chr5	151791054	Missense_Mutation	NA	A115S	0.19
LUAD	chr5	151803918	Missense_Mutation	novel	V410I	0.4
LUAD	chr5	151794159	Missense_Mutation	NA	G118W	0.1
LUSC	chr5	151799892	Missense_Mutation	NA	R283C	0.18
LUSC	chr5	151800771	Missense_Mutation	novel	V366M	0.07	NTF2
LUSC	chr5	151790965	Missense_Mutation	rs773786985	T85M	0.64
LUSC	chr5	151786676	Frame_Shift_Ins	novel	*Y20Ffs5**	0.18
MESO	chr5	151786588	5'UTR	rs771933390		0.15
OV	chr5	151791266	Intron	novel		0.25
OV	chr5	151799992	Missense_Mutation	NA	P316R	0.2
OV	chr5	151800798	Frame_Shift_Del	novel	*K376Nfs33**	0.04	NTF2
OV	chr5	151797339	Frame_Shift_Ins	novel	*L219Ifs7**	0.23
PAAD	chr5	151786657	Missense_Mutation	novel	R13W	0.09
PAAD	chr5	151795549	Silent	rs750288335	G171G	0.18
PAAD	chr5	151803900	Missense_Mutation	novel	G404C	0.07
PRAD	chr5	151799959	In_Frame_Ins	novel	E305delinsDLP	0.07
READ	chr5	151799965	Missense_Mutation	rs775783436	R307Q	0.17
READ	chr5	151799965	Missense_Mutation	rs775783436	R307Q	0.38
SARC	chr5	151803969	Missense_Mutation	novel	R427C	0.5
SARC	chr5	151803935	Silent	novel	T415T	0.52
SKCM	chr5	151794240	Missense_Mutation	novel	P145S	0.55
SKCM	chr5	151799892	Missense_Mutation	NA	R283C	0.43
SKCM	chr5	151786644	Silent	novel	P8P	0.29
SKCM	chr5	151786645	Silent	novel	L9L	0.3
STAD	chr5	151799892	Missense_Mutation	NA	R283C	0.14
STAD	chr5	151786595	5'UTR	novel		0.2
STAD	chr5	151791131	Intron	novel		0.19
STAD	chr5	151786595	5'UTR	novel		0.07
STAD	chr5	151790976	Missense_Mutation	NA	G89C	0.29
STAD	chr5	151800296	Missense_Mutation	NA	G345D	0.07	NTF2
STAD	chr5	151803909	Missense_Mutation	NA	R407C	0.34
STAD	chr5	151799914	Missense_Mutation	NA	S290C	0.28
STAD	chr5	151799975	Silent	NA	I310I	0.46
STAD	chr5	151799295	Frame_Shift_Ins	novel	*V277Sfs11**	0.31
STAD	chr5	151791049	Missense_Mutation	NA	V113A	0.18
STAD	chr5	151786628	Missense_Mutation	rs769813798	M3T	0.28
THYM	chr5	151794158	Splice_Site	novel	X118_splice	0.07
UCEC	chr5	151790405	Splice_Site	NA	X59_splice	0.37
UCEC	chr5	151803994	Missense_Mutation	NA	R435Q	0.36
UCEC	chr5	151803921	Missense_Mutation	novel	E411K	0.09
UCEC	chr5	151805290	3'UTR	novel		0.16
UCEC	chr5	151805219	3'UTR	novel		0.93
UCEC	chr5	151790384	Missense_Mutation	NA	D53N	0.27
UCEC	chr5	151803961	Missense_Mutation	NA	R424Q	0.21
UCEC	chr5	151804080	Missense_Mutation	novel	P464S	0.33
UCEC	chr5	151804677	3'UTR	novel		0.33
UCEC	chr5	151800849	Nonsense_Mutation	novel	Q392*	0.06	NTF2
UCEC	chr5	151786595	5'UTR	novel		0.42
UCEC	chr5	151795543	Missense_Mutation	novel	D169E	0.12
UCEC	chr5	151803893	Missense_Mutation	novel	M401I	0.16
UCEC	chr5	151797290	Silent	novel	E201E	0.39
UCEC	chr5	151790913	Nonsense_Mutation	novel	Q68*	0.36
UCEC	chr5	151790915	Missense_Mutation	NA	Q68H	0.15
UCEC	chr5	151791143	Intron	novel		0.02
UCEC	chr5	151797339	Missense_Mutation	NA	V218I	0.2
UCEC	chr5	151799911	Missense_Mutation	novel	E289A	0.08
UCEC	chr5	151803937	Missense_Mutation	NA	R416Q	0.14
UCEC	chr5	151790943	Missense_Mutation	novel	R78G	0.09
UCEC	chr5	151804079	Silent	NA	A463A	0.45
UCEC	chr5	151804929	3'UTR	rs200497080		0.46
UCEC	chr5	151804685	3'UTR	novel		0.22
UCEC	chr5	151790966	Silent	rs200897287	T85T	0.41
UCEC	chr5	151800220	Missense_Mutation	novel	R320S	0.18
UCEC	chr5	151804506	3'UTR	novel		0.42
UCEC	chr5	151804929	3'UTR	rs200497080		0.52
UCEC	chr5	151795519	Silent	NA	Q161Q	0.34
UCEC	chr5	151795567	Silent	NA	A177A	0.36
UCEC	chr5	151795523	Missense_Mutation	novel	P163A	0.44
UCEC	chr5	151804085	Silent	novel	R465R	0.52
UCEC	chr5	151795519	Missense_Mutation	novel	Q161H	0.41
UCEC	chr5	151791143	Intron	novel		0.03
UCEC	chr5	151804079	Silent	NA	A463A	0.4
UCEC	chr5	151791030	Missense_Mutation	novel	R107G	0.38
UCEC	chr5	151795576	Splice_Site	novel	X180_splice	0.57
UCEC	chr5	151804662	3'UTR	novel		0.33
UCEC	chr5	151804929	3'UTR	rs200497080		0.34
UCEC	chr5	151804662	3'UTR	novel		0.41
UCEC	chr5	151804929	3'UTR	rs200497080		0.41
UCEC	chr5	151803970	Missense_Mutation	novel	R427H	0.37
UCEC	chr5	151805298	3'UTR	novel		0.23
UCEC	chr5	151803961	Missense_Mutation	NA	R424Q	0.24
UCEC	chr5	151799910	Missense_Mutation	NA	E289K	0.5
UCEC	chr5	151804929	3'UTR	rs200497080		0.58
UCEC	chr5	151799239	Missense_Mutation	novel	K257E	0.24
UCEC	chr5	151805269	3'UTR	novel		0.32
UCEC	chr5	151805221	3'UTR	novel		0.41
UCEC	chr5	151790944	Missense_Mutation	rs370340219	R78H	0.3
UCEC	chr5	151800334	Missense_Mutation	NA	D358N	0.32	NTF2
UCEC	chr5	151791129	Intron	novel		0.09
UCEC	chr5	151804662	3'UTR	novel		0.3
UCEC	chr5	151791106	Intron	novel		0.41
UCEC	chr5	151804929	3'UTR	rs200497080		0.6
UCEC	chr5	151803975	Missense_Mutation	rs759164636	R429W	0.48
UCEC	chr5	151799932	Missense_Mutation	NA	R296I	0.25
UCEC	chr5	151790363	Missense_Mutation	novel	D46N	0.23
UCEC	chr5	151791019	Missense_Mutation	novel	Q103R	0.38
UCEC	chr5	151804719	3'UTR	novel		0.47
UCEC	chr5	151804084	Missense_Mutation	rs757200884	R465Q	0.33

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	AMP	0.1042	0.069756
KIRP	DEL	0.0382	0.11554
LAML	DEL	0.0838	1.2971e-07
LGG	DEL	0.0858	1.86e-07
LUSC	DEL	0.6208	0.002071
MESO	DEL	0.1264	0.20184
PRAD	AMP	0.0244	0.16448
SKCM	DEL	0.2943	2.2081e-08
THCA	AMP	0.0361	0.075436
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0062	Kaplan-Meier Survival Analysis
SARC	0.0019	Kaplan-Meier Survival Analysis
HNSC	0.041	Kaplan-Meier Survival Analysis
PRAD	0.029	Kaplan-Meier Survival Analysis
BRCA	0.031	Kaplan-Meier Survival Analysis
ESCA	0.016	Kaplan-Meier Survival Analysis
KIRP	0.0011	Kaplan-Meier Survival Analysis
COAD	0.018	Kaplan-Meier Survival Analysis
PAAD	0.0014	Kaplan-Meier Survival Analysis
CESC	0.05	Kaplan-Meier Survival Analysis
READ	0.0012	Kaplan-Meier Survival Analysis
LAML	0.0021	Kaplan-Meier Survival Analysis
KICH	0.011	Kaplan-Meier Survival Analysis
LIHC	0.0027	Kaplan-Meier Survival Analysis
LGG	0.041	Kaplan-Meier Survival Analysis
THCA	0.044	Kaplan-Meier Survival Analysis
LUAD	0.0034	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742