EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000145912 (Gene tree)
Gene ID: 55651
Gene Symbol: NHP2
Alias: FLJ20479|NOLA2
Full Name: NHP2 ribonucleoprotein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 4,508 bases
Position: chr5:178,149,460-178,153,967
Accession: 14377
RBP type: canonical RBP
Summary: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000274606	Ribosomal_L7Ae	PF01248.26	7.9e-23	1	1
ENSP00000423849	Ribosomal_L7Ae	PF01248.26	1.6e-15	1	1
ENSP00000423803	Ribosomal_L7Ae	PF01248.26	1.6e-15	1	1
ENSP00000431126	Ribosomal_L7Ae	PF01248.26	3.9e-14	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
9848653	Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure.	RNA	1998 Dec	Watkins NJ	-
11433018	Accumulation of H/ACA snoRNPs depends on the integrity of the conserved central domain of the RNA-binding protein Nhp2p.	Nucleic Acids Res	2001 Jul 1	Henras A	-
29177505	Efficient RNA pseudouridylation by eukaryotic H/ACA ribonucleoproteins requires high affinity binding and correct positioning of guide RNA.	Nucleic Acids Res	2018 Jan 25	Caton EA	doi: 10.1093/nar/gkx1167.
12403468	The SBP2 and 15.5 kD/Snu13p proteins share the same RNA binding domain: identification of SBP2 amino acids important to SECIS RNA binding.	RNA	2002 Oct	Allmang C	-
12515383	Naf1 p is a box H/ACA snoRNP assembly factor.	RNA	2002 Dec	Fatica A	-
12020816	Expression of the human homologue of the small nucleolar RNA-binding protein NHP2 gene during monocytic differentiation of U937 cells.	Biochim Biophys Acta	2002 May 3	Kang HS	-
21708174	Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.	J Mol Biol	2011 Sep 2	Koo BK	doi: 10.1016/j.jmb.2011.06.022
10791972	Association of yeast RNA polymerase I with a nucleolar substructure active in rRNA synthesis and processing.	J Cell Biol	2000 May 1	Fath S	-
22117216	Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita.	EMBO J	2011 Nov 25	Li S	doi: 10.1038/emboj.2011.427.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000314397	NHP2-202	599	-	ENSP00000366276	90 (aa)	-	J3QSY4
ENST00000510363	NHP2-204	566	-	-	- (aa)	-	-
ENST00000514354	NHP2-206	472	-	ENSP00000423803	135 (aa)	-	D6RCB9
ENST00000502263	NHP2-203	552	-	ENSP00000431126	85 (aa)	-	H0YC83
ENST00000274606	NHP2-201	865	-	ENSP00000274606	153 (aa)	-	Q9NX24
ENST00000511078	NHP2-205	475	-	ENSP00000423849	132 (aa)	-	D6RC52

Gene Model

Click here to download ENSG00000145912's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000145912	Blood Glucose	8.1310000E-005	-
ENSG00000145912	Blood Glucose	5.6980000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000145912's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000145912	NHP2	72	40.404	ENSG00000100138	SNU13	95	51.282

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000145912	NHP2	100	69.935	ENSAPOG00000004742	nhp2	100	69.935	Acanthochromis_polyacanthus
ENSG00000145912	NHP2	100	95.425	ENSAMEG00000006471	NHP2	100	95.425	Ailuropoda_melanoleuca
ENSG00000145912	NHP2	86	78.030	ENSACIG00000007968	nhp2	100	72.152	Amphilophus_citrinellus
ENSG00000145912	NHP2	100	69.935	ENSAOCG00000016311	nhp2	100	69.935	Amphiprion_ocellaris
ENSG00000145912	NHP2	100	69.935	ENSAPEG00000008765	nhp2	100	69.935	Amphiprion_percula
ENSG00000145912	NHP2	100	71.613	ENSATEG00000009651	nhp2	100	71.613	Anabas_testudineus
ENSG00000145912	NHP2	86	85.606	ENSACAG00000006692	NHP2	92	81.250	Anolis_carolinensis
ENSG00000145912	NHP2	100	99.346	ENSANAG00000023290	NHP2	100	99.346	Aotus_nancymaae
ENSG00000145912	NHP2	84	82.171	ENSANAG00000031552	-	99	82.171	Aotus_nancymaae
ENSG00000145912	NHP2	87	78.195	ENSACLG00000001082	nhp2	100	71.429	Astatotilapia_calliptera
ENSG00000145912	NHP2	100	74.510	ENSAMXG00000005845	nhp2	100	74.510	Astyanax_mexicanus
ENSG00000145912	NHP2	100	94.771	ENSBTAG00000006374	NHP2	100	94.771	Bos_taurus
ENSG00000145912	NHP2	99	44.375	WBGene00012964	Y48A6B.3	98	44.375	Caenorhabditis_elegans
ENSG00000145912	NHP2	100	98.039	ENSCJAG00000038564	-	100	98.039	Callithrix_jacchus
ENSG00000145912	NHP2	100	96.078	ENSCJAG00000023093	-	100	96.078	Callithrix_jacchus
ENSG00000145912	NHP2	100	94.771	ENSCAFG00000000240	NHP2	100	94.771	Canis_familiaris
ENSG00000145912	NHP2	92	92.562	ENSCAFG00020003649	-	53	92.562	Canis_lupus_dingo
ENSG00000145912	NHP2	100	94.771	ENSCHIG00000015159	NHP2	100	94.771	Capra_hircus
ENSG00000145912	NHP2	100	69.281	ENSTSYG00000008150	NHP2	100	69.281	Carlito_syrichta
ENSG00000145912	NHP2	100	96.078	ENSCPOG00000033753	NHP2	100	96.078	Cavia_porcellus
ENSG00000145912	NHP2	100	81.046	ENSCCAG00000027964	-	100	81.046	Cebus_capucinus
ENSG00000145912	NHP2	100	79.739	ENSCCAG00000034664	-	100	79.739	Cebus_capucinus
ENSG00000145912	NHP2	100	99.346	ENSCCAG00000034815	NHP2	100	99.346	Cebus_capucinus
ENSG00000145912	NHP2	100	100.000	ENSCATG00000043608	NHP2	100	100.000	Cercocebus_atys
ENSG00000145912	NHP2	100	93.464	ENSCLAG00000016005	NHP2	100	93.464	Chinchilla_lanigera
ENSG00000145912	NHP2	100	100.000	ENSCSAG00000008690	NHP2	100	100.000	Chlorocebus_sabaeus
ENSG00000145912	NHP2	100	93.464	ENSCHOG00000013038	NHP2	100	93.464	Choloepus_hoffmanni
ENSG00000145912	NHP2	86	84.091	ENSCPBG00000022106	NHP2	100	77.124	Chrysemys_picta_bellii
ENSG00000145912	NHP2	85	63.077	ENSCSAVG00000008036	-	86	63.077	Ciona_savignyi
ENSG00000145912	NHP2	100	99.346	ENSCANG00000031562	NHP2	100	99.346	Colobus_angolensis_palliatus
ENSG00000145912	NHP2	96	94.186	ENSCANG00000038441	-	97	89.865	Colobus_angolensis_palliatus
ENSG00000145912	NHP2	100	90.196	ENSCGRG00001005326	Nhp2	100	90.196	Cricetulus_griseus_chok1gshd
ENSG00000145912	NHP2	100	90.196	ENSCGRG00000013680	Nhp2	100	90.196	Cricetulus_griseus_crigri
ENSG00000145912	NHP2	100	72.258	ENSCSEG00000006761	nhp2	100	72.258	Cynoglossus_semilaevis
ENSG00000145912	NHP2	100	71.242	ENSDARG00000069422	nhp2	100	71.242	Danio_rerio
ENSG00000145912	NHP2	100	94.118	ENSDNOG00000017150	NHP2	94	94.118	Dasypus_novemcinctus
ENSG00000145912	NHP2	100	96.078	ENSDORG00000003312	Nhp2	100	96.078	Dipodomys_ordii
ENSG00000145912	NHP2	100	41.875	FBgn0029148	NHP2	100	41.875	Drosophila_melanogaster
ENSG00000145912	NHP2	100	92.208	ENSETEG00000006774	NHP2	100	92.208	Echinops_telfairi
ENSG00000145912	NHP2	100	94.771	ENSEASG00005012569	NHP2	100	94.771	Equus_asinus_asinus
ENSG00000145912	NHP2	100	93.464	ENSECAG00000022963	NHP2	87	93.464	Equus_caballus
ENSG00000145912	NHP2	69	88.136	ENSELUG00000021981	nhp2	85	81.000	Esox_lucius
ENSG00000145912	NHP2	100	95.425	ENSFCAG00000015541	NHP2	100	95.425	Felis_catus
ENSG00000145912	NHP2	86	81.679	ENSFALG00000008774	NHP2	91	78.082	Ficedula_albicollis
ENSG00000145912	NHP2	100	86.928	ENSFDAG00000008131	NHP2	100	86.928	Fukomys_damarensis
ENSG00000145912	NHP2	100	71.154	ENSFHEG00000000431	nhp2	100	71.154	Fundulus_heteroclitus
ENSG00000145912	NHP2	87	81.203	ENSGMOG00000000278	nhp2	100	74.834	Gadus_morhua
ENSG00000145912	NHP2	79	83.471	ENSGALG00000033666	NHP2	78	80.303	Gallus_gallus
ENSG00000145912	NHP2	87	77.444	ENSGAFG00000009838	nhp2	100	72.436	Gambusia_affinis
ENSG00000145912	NHP2	88	74.074	ENSGACG00000020889	nhp2	100	68.627	Gasterosteus_aculeatus
ENSG00000145912	NHP2	72	86.885	ENSGAGG00000006901	NHP2	80	81.000	Gopherus_agassizii
ENSG00000145912	NHP2	100	82.353	ENSGGOG00000027198	-	100	82.353	Gorilla_gorilla
ENSG00000145912	NHP2	100	82.353	ENSGGOG00000040409	-	100	82.353	Gorilla_gorilla
ENSG00000145912	NHP2	86	78.788	ENSHBUG00000010207	nhp2	100	72.078	Haplochromis_burtoni
ENSG00000145912	NHP2	100	96.078	ENSHGLG00000013630	NHP2	100	96.078	Heterocephalus_glaber_female
ENSG00000145912	NHP2	100	82.353	ENSHGLG00000014450	-	100	82.353	Heterocephalus_glaber_female
ENSG00000145912	NHP2	100	82.353	ENSHGLG00100003440	-	100	82.353	Heterocephalus_glaber_male
ENSG00000145912	NHP2	100	96.078	ENSHGLG00100007298	NHP2	100	96.078	Heterocephalus_glaber_male
ENSG00000145912	NHP2	100	82.353	ENSHGLG00100005282	-	100	82.353	Heterocephalus_glaber_male
ENSG00000145912	NHP2	100	68.354	ENSHCOG00000019552	nhp2	100	68.354	Hippocampus_comes
ENSG00000145912	NHP2	100	76.471	ENSIPUG00000024197	NHP2	100	76.471	Ictalurus_punctatus
ENSG00000145912	NHP2	100	95.425	ENSSTOG00000003235	NHP2	100	95.425	Ictidomys_tridecemlineatus
ENSG00000145912	NHP2	100	91.503	ENSJJAG00000016469	Nhp2	100	92.157	Jaculus_jaculus
ENSG00000145912	NHP2	100	69.677	ENSLBEG00000002128	nhp2	100	69.677	Labrus_bergylta
ENSG00000145912	NHP2	100	74.675	ENSLACG00000017167	NHP2	99	74.675	Latimeria_chalumnae
ENSG00000145912	NHP2	88	81.481	ENSLOCG00000009630	nhp2	100	75.163	Lepisosteus_oculatus
ENSG00000145912	NHP2	100	93.464	ENSLAFG00000012828	NHP2	100	93.464	Loxodonta_africana
ENSG00000145912	NHP2	100	100.000	ENSMFAG00000032376	NHP2	100	100.000	Macaca_fascicularis
ENSG00000145912	NHP2	100	98.824	ENSMMUG00000018757	-	100	98.824	Macaca_mulatta
ENSG00000145912	NHP2	100	72.549	ENSMMUG00000046673	-	100	72.549	Macaca_mulatta
ENSG00000145912	NHP2	100	100.000	ENSMNEG00000038787	NHP2	100	100.000	Macaca_nemestrina
ENSG00000145912	NHP2	100	100.000	ENSMLEG00000028639	NHP2	100	100.000	Mandrillus_leucophaeus
ENSG00000145912	NHP2	100	73.077	ENSMAMG00000022425	nhp2	100	73.077	Mastacembelus_armatus
ENSG00000145912	NHP2	87	78.195	ENSMZEG00005027834	nhp2	100	71.429	Maylandia_zebra
ENSG00000145912	NHP2	69	83.051	ENSMGAG00000003917	NHP2	100	86.000	Meleagris_gallopavo
ENSG00000145912	NHP2	100	94.771	ENSMICG00000005379	NHP2	100	94.771	Microcebus_murinus
ENSG00000145912	NHP2	100	89.542	ENSMOCG00000022171	Nhp2	100	89.542	Microtus_ochrogaster
ENSG00000145912	NHP2	87	74.436	ENSMMOG00000016811	nhp2	100	69.231	Mola_mola
ENSG00000145912	NHP2	100	79.870	ENSMODG00000004231	NHP2	100	79.870	Monodelphis_domestica
ENSG00000145912	NHP2	99	72.848	ENSMALG00000009613	nhp2	97	72.848	Monopterus_albus
ENSG00000145912	NHP2	100	90.196	MGP_CAROLIEiJ_G0016312	Nhp2	100	90.196	Mus_caroli
ENSG00000145912	NHP2	100	89.542	ENSMUSG00000001056	Nhp2	100	89.542	Mus_musculus
ENSG00000145912	NHP2	100	89.542	MGP_PahariEiJ_G0017447	Nhp2	100	89.542	Mus_pahari
ENSG00000145912	NHP2	100	89.542	MGP_SPRETEiJ_G0017156	Nhp2	100	89.542	Mus_spretus
ENSG00000145912	NHP2	100	94.194	ENSMPUG00000000747	NHP2	100	94.194	Mustela_putorius_furo
ENSG00000145912	NHP2	100	93.464	ENSMLUG00000003377	NHP2	100	93.464	Myotis_lucifugus
ENSG00000145912	NHP2	100	94.118	ENSNGAG00000021818	Nhp2	100	94.118	Nannospalax_galili
ENSG00000145912	NHP2	86	79.545	ENSNBRG00000018016	nhp2	100	72.727	Neolamprologus_brichardi
ENSG00000145912	NHP2	100	85.535	ENSNLEG00000015765	NHP2	100	85.535	Nomascus_leucogenys
ENSG00000145912	NHP2	100	79.221	ENSMEUG00000003839	NHP2	100	79.221	Notamacropus_eugenii
ENSG00000145912	NHP2	89	92.500	ENSOPRG00000007907	NHP2	100	77.124	Ochotona_princeps
ENSG00000145912	NHP2	100	95.425	ENSODEG00000006948	NHP2	100	95.425	Octodon_degus
ENSG00000145912	NHP2	86	80.303	ENSONIG00000017865	nhp2	100	73.377	Oreochromis_niloticus
ENSG00000145912	NHP2	99	95.395	ENSOCUG00000016057	-	99	95.395	Oryctolagus_cuniculus
ENSG00000145912	NHP2	99	95.395	ENSOCUG00000016091	-	99	95.395	Oryctolagus_cuniculus
ENSG00000145912	NHP2	100	73.203	ENSORLG00000029195	nhp2	100	73.203	Oryzias_latipes
ENSG00000145912	NHP2	100	73.203	ENSORLG00020003277	nhp2	100	73.203	Oryzias_latipes_hni
ENSG00000145912	NHP2	100	73.203	ENSORLG00015007851	nhp2	100	73.203	Oryzias_latipes_hsok
ENSG00000145912	NHP2	100	71.895	ENSOMEG00000017381	nhp2	87	71.895	Oryzias_melastigma
ENSG00000145912	NHP2	100	92.258	ENSOGAG00000016108	NHP2	100	92.258	Otolemur_garnettii
ENSG00000145912	NHP2	100	86.928	ENSOARG00000006274	NHP2	100	86.928	Ovis_aries
ENSG00000145912	NHP2	100	83.007	ENSPPAG00000038834	-	100	83.007	Pan_paniscus
ENSG00000145912	NHP2	100	100.000	ENSPPAG00000028668	NHP2	100	100.000	Pan_paniscus
ENSG00000145912	NHP2	100	95.425	ENSPPRG00000022505	NHP2	100	95.425	Panthera_pardus
ENSG00000145912	NHP2	69	98.305	ENSPTIG00000021731	NHP2	81	96.078	Panthera_tigris_altaica
ENSG00000145912	NHP2	100	99.346	ENSPTRG00000048185	NHP2	100	99.346	Pan_troglodytes
ENSG00000145912	NHP2	94	85.417	ENSPTRG00000049011	-	100	85.417	Pan_troglodytes
ENSG00000145912	NHP2	94	85.417	ENSPTRG00000050430	-	100	85.417	Pan_troglodytes
ENSG00000145912	NHP2	100	100.000	ENSPANG00000019121	NHP2	100	100.000	Papio_anubis
ENSG00000145912	NHP2	90	79.562	ENSPKIG00000006410	nhp2	100	75.163	Paramormyrops_kingsleyae
ENSG00000145912	NHP2	93	73.944	ENSPMGG00000002916	nhp2	87	73.944	Periophthalmus_magnuspinnatus
ENSG00000145912	NHP2	100	88.889	ENSPEMG00000023567	Nhp2	100	88.889	Peromyscus_maniculatus_bairdii
ENSG00000145912	NHP2	93	66.667	ENSPMAG00000009888	nhp2	93	66.667	Petromyzon_marinus
ENSG00000145912	NHP2	100	79.221	ENSPCIG00000002727	-	100	79.221	Phascolarctos_cinereus
ENSG00000145912	NHP2	72	83.636	ENSPCIG00000019848	-	92	83.636	Phascolarctos_cinereus
ENSG00000145912	NHP2	100	70.513	ENSPFOG00000002315	nhp2	100	70.513	Poecilia_formosa
ENSG00000145912	NHP2	100	69.872	ENSPLAG00000019287	nhp2	100	69.872	Poecilia_latipinna
ENSG00000145912	NHP2	100	70.513	ENSPMEG00000024346	nhp2	100	70.513	Poecilia_mexicana
ENSG00000145912	NHP2	66	83.929	ENSPREG00000005005	nhp2	95	73.874	Poecilia_reticulata
ENSG00000145912	NHP2	100	99.346	ENSPPYG00000016105	NHP2	100	99.346	Pongo_abelii
ENSG00000145912	NHP2	100	94.118	ENSPCOG00000020708	NHP2	100	94.118	Propithecus_coquereli
ENSG00000145912	NHP2	100	92.157	ENSPVAG00000001647	NHP2	100	92.157	Pteropus_vampyrus
ENSG00000145912	NHP2	86	78.788	ENSPNYG00000022418	nhp2	100	72.078	Pundamilia_nyererei
ENSG00000145912	NHP2	100	71.895	ENSPNAG00000013779	nhp2	100	71.895	Pygocentrus_nattereri
ENSG00000145912	NHP2	69	98.305	ENSRNOG00000004247	Nhp2	89	93.519	Rattus_norvegicus
ENSG00000145912	NHP2	100	90.196	ENSRNOG00000049622	LOC103690013	100	90.196	Rattus_norvegicus
ENSG00000145912	NHP2	100	100.000	ENSRBIG00000018610	NHP2	100	100.000	Rhinopithecus_bieti
ENSG00000145912	NHP2	100	80.392	ENSRROG00000044295	-	100	80.392	Rhinopithecus_roxellana
ENSG00000145912	NHP2	100	100.000	ENSRROG00000043373	NHP2	100	100.000	Rhinopithecus_roxellana
ENSG00000145912	NHP2	73	54.839	YDL208W	-	82	50.000	Saccharomyces_cerevisiae
ENSG00000145912	NHP2	100	99.346	ENSSBOG00000027889	NHP2	100	99.346	Saimiri_boliviensis_boliviensis
ENSG00000145912	NHP2	100	79.221	ENSSHAG00000015581	NHP2	100	79.221	Sarcophilus_harrisii
ENSG00000145912	NHP2	100	73.203	ENSSFOG00015017061	nhp2	100	73.203	Scleropages_formosus
ENSG00000145912	NHP2	88	75.556	ENSSMAG00000011251	nhp2	100	70.513	Scophthalmus_maximus
ENSG00000145912	NHP2	100	71.895	ENSSDUG00000023355	nhp2	100	71.895	Seriola_dumerili
ENSG00000145912	NHP2	69	86.441	ENSSLDG00000006293	nhp2	51	74.775	Seriola_lalandi_dorsalis
ENSG00000145912	NHP2	94	80.556	ENSSPUG00000005173	NHP2	93	80.556	Sphenodon_punctatus
ENSG00000145912	NHP2	100	68.627	ENSSPAG00000011696	nhp2	100	68.627	Stegastes_partitus
ENSG00000145912	NHP2	100	75.163	ENSSSCG00000009710	-	100	75.163	Sus_scrofa
ENSG00000145912	NHP2	100	93.464	ENSSSCG00000039635	-	86	93.464	Sus_scrofa
ENSG00000145912	NHP2	71	80.000	ENSTGUG00000000368	NHP2	95	71.429	Taeniopygia_guttata
ENSG00000145912	NHP2	86	78.788	ENSTRUG00000008183	nhp2	100	71.698	Takifugu_rubripes
ENSG00000145912	NHP2	86	70.588	ENSTNIG00000004219	nhp2	95	65.385	Tetraodon_nigroviridis
ENSG00000145912	NHP2	100	95.425	ENSUAMG00000025154	NHP2	100	95.425	Ursus_americanus
ENSG00000145912	NHP2	99	90.728	ENSUMAG00000023916	NHP2	97	90.728	Ursus_maritimus
ENSG00000145912	NHP2	89	88.750	ENSVPAG00000010059	NHP2	100	90.090	Vicugna_pacos
ENSG00000145912	NHP2	100	80.556	ENSVVUG00000001030	NHP2	100	80.556	Vulpes_vulpes
ENSG00000145912	NHP2	86	79.389	ENSXETG00000006731	nhp2	88	79.389	Xenopus_tropicalis
ENSG00000145912	NHP2	87	77.444	ENSXMAG00000007031	nhp2	100	72.436	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000469	cleavage involved in rRNA processing	21873635.	IBA	Process
GO:0000470	maturation of LSU-rRNA	21873635.	IBA	Process
GO:0000784	nuclear chromosome, telomeric region	19135898.	HDA	Component
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003723	RNA binding	18082603.20351177.22527283.	IPI	Function
GO:0005515	protein binding	23685356.25416956.25910212.30021884.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005697	telomerase holoenzyme complex	18082603.29695869.	IDA	Component
GO:0005697	telomerase holoenzyme complex	20351177.22527283.	TAS	Component
GO:0005732	small nucleolar ribonucleoprotein complex	-	ISS	Component
GO:0007004	telomere maintenance via telomerase	29695869.	IDA	Process
GO:0007004	telomere maintenance via telomerase	22527283.	TAS	Process
GO:0031118	rRNA pseudouridine synthesis	21873635.	IBA	Process
GO:0031118	rRNA pseudouridine synthesis	-	ISS	Process
GO:0031118	rRNA pseudouridine synthesis	-	TAS	Process
GO:0031120	snRNA pseudouridine synthesis	21873635.	IBA	Process
GO:0031429	box H/ACA snoRNP complex	21873635.	IBA	Component
GO:0031429	box H/ACA snoRNP complex	18082603.	IDA	Component
GO:0031429	box H/ACA snoRNP complex	22527283.	TAS	Component
GO:0034513	box H/ACA snoRNA binding	21873635.	IBA	Function
GO:0034513	box H/ACA snoRNA binding	18082603.	IPI	Function
GO:0070034	telomerase RNA binding	18082603.20351177.22527283.	IPI	Function
GO:0072589	box H/ACA scaRNP complex	22527283.	TAS	Component
GO:0090661	box H/ACA telomerase RNP complex	18082603.	IDA	Component
GO:0090661	box H/ACA telomerase RNP complex	22527283.	TAS	Component
GO:1904874	positive regulation of telomerase RNA localization to Cajal body	25467444.	HMP	Process