EuRBPDB

Description

Ensembl ID: ENSG00000147471 (Gene tree)
Gene ID: 11212
Gene Symbol: PLPBP
Alias: PROSC
Full Name: pyridoxal phosphate binding protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 17,186 bases
Position: chr8:37,762,583-37,779,768
Accession: 9457
RBP type: non-canonical RBP
Summary: This gene encodes a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 2017]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000520073	PLPBP-203	770	-	-	- (aa)	-	-
ENST00000328195	PLPBP-201	2558	-	ENSP00000333551	275 (aa)	-	O94903
ENST00000523994	PLPBP-209	559	-	-	- (aa)	-	-
ENST00000518036	PLPBP-202	558	-	ENSP00000428005	74 (aa)	-	E5RFZ4
ENST00000521631	PLPBP-204	272	-	-	- (aa)	-	-
ENST00000523358	PLPBP-207	516	-	ENSP00000427778	152 (aa)	-	E5RG77
ENST00000522808	PLPBP-205	753	-	-	- (aa)	-	-
ENST00000523521	PLPBP-208	384	-	ENSP00000429425	128 (aa)	-	H0YBG2
ENST00000523187	PLPBP-206	569	-	ENSP00000427886	137 (aa)	-	E5RFX7

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005737	cytoplasm	10496079.	NAS	Component
GO:0008150	biological_process	-	ND	Process
GO:0030170	pyridoxal phosphate binding	21873635.	IBA	Function