EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000148396 (Gene tree)
Gene ID: 9919
Gene Symbol: SEC16A
Alias: p250|Sec16L|KIAA0310
Full Name: SEC16 homolog A, endoplasmic reticulum export factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 44,454 bases
Position: chr9:136,440,096-136,484,549
Accession: 29006
RBP type: non-canonical RBP
Summary: This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000467838	SEC16A-208	1988	-	-	- (aa)	-	-
ENST00000313084	SEC16A-204	3073	-	ENSP00000317437	385 (aa)	-	Q8N9G1
ENST00000313050	SEC16A-203	8806	XM_005266134	ENSP00000325827	2357 (aa)	XP_005266191	J3KNL6
ENST00000371706	SEC16A-205	8093	XM_011519259	ENSP00000360771	2134 (aa)	XP_011517561	O15027
ENST00000472305	SEC16A-209	537	-	-	- (aa)	-	-
ENST00000277537	SEC16A-201	3910	-	ENSP00000277537	751 (aa)	-	A0A0C4DH09
ENST00000290037	SEC16A-202	8982	XM_011519251	ENSP00000290037	2334 (aa)	XP_011517553	F1T0I1
ENST00000431893	SEC16A-206	6465	XM_011519254	ENSP00000387583	2154 (aa)	XP_011517556	O15027
ENST00000453963	SEC16A-207	4834	-	ENSP00000403525	1059 (aa)	-	X6RGP5

Gene Model

Click here to download ENSG00000148396's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000148396	Skin Neoplasms	8E-9	27424798

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000148396	rs57994353	9	136462535	C	Cutaneous squamous cell carcinoma	27424798		1.12	EFO_1001927
ENSG00000148396	rs57994353	9	136462535	C	Eosinophil counts	27863252	[0.016-0.031] unit increase	0.02311792	EFO_0004842
ENSG00000148396	rs1127152	9	136441147	?	Red blood cell count	30595370			EFO_0004305

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000148396's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000139	Golgi membrane	-	IEA	Component
GO:0005515	protein binding	17428803.19638414.22355596.25201882.28067262.28442536.29187380.29300766.	IPI	Function
GO:0005783	endoplasmic reticulum	-	IDA	Component
GO:0005789	endoplasmic reticulum membrane	29300766.	IDA	Component
GO:0005794	Golgi apparatus	-	IDA	Component
GO:0005829	cytosol	17428803.21768384.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006888	ER to Golgi vesicle-mediated transport	22355596.	IMP	Process
GO:0007029	endoplasmic reticulum organization	21873635.	IBA	Process
GO:0007029	endoplasmic reticulum organization	21768384.	IDA	Process
GO:0007029	endoplasmic reticulum organization	17428803.28442536.	IMP	Process
GO:0007030	Golgi organization	21873635.	IBA	Process
GO:0012507	ER to Golgi transport vesicle membrane	21873635.	IBA	Component
GO:0021762	substantia nigra development	22926577.	HEP	Process
GO:0031090	organelle membrane	17428803.	IDA	Component
GO:0032527	protein exit from endoplasmic reticulum	-	ISS	Process
GO:0034976	response to endoplasmic reticulum stress	28067262.	IDA	Process
GO:0043000	Golgi to plasma membrane CFTR protein transport	28067262.	IMP	Process
GO:0048208	COPII vesicle coating	21873635.	IBA	Process
GO:0048208	COPII vesicle coating	-	TAS	Process
GO:0048471	perinuclear region of cytoplasm	-	ISS	Component
GO:0050821	protein stabilization	29300766.	IMP	Process
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	21873635.	IBA	Process
GO:0070971	endoplasmic reticulum exit site	21873635.	IBA	Component
GO:0070971	endoplasmic reticulum exit site	19638414.22355596.25201882.28067262.	IDA	Component
GO:0070973	protein localization to endoplasmic reticulum exit site	21873635.	IBA	Process
GO:0070973	protein localization to endoplasmic reticulum exit site	28442536.	IMP	Process
GO:0072659	protein localization to plasma membrane	-	ISS	Process