EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000150990 (Gene tree)
Gene ID: 57647
Gene Symbol: DHX37
Alias: KIAA1517|MGC4322|MGC2695|Dhr1|DDX37
Full Name: DEAH-box helicase 37
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 42,308 bases
Position: chr12:124,946,824-124,989,131
Accession: 17210
RBP type: canonical RBP
Summary: This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000439009	DEAD	PF00270.29	3.6e-09	1	1
ENSP00000311135	DEAD	PF00270.29	4.3e-09	1	1
ENSP00000439009	HA2	PF04408.23	2.1e-27	1	1
ENSP00000311135	HA2	PF04408.23	2.2e-26	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
30910870	Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.	RNA	2019 Jun	Boneberg FM	doi: 10.1261/rna.069609.118

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000507267	DHX37-202	819	-	-	- (aa)	-	-
ENST00000542400	DHX37-204	3065	-	-	- (aa)	-	-
ENST00000543962	DHX37-205	669	-	ENSP00000443661	133 (aa)	-	F5H8E1
ENST00000539298	DHX37-203	4550	-	-	- (aa)	-	-
ENST00000544745	DHX37-206	4112	-	ENSP00000439009	962 (aa)	-	F5H3Y4
ENST00000308736	DHX37-201	4550	XM_005253590	ENSP00000311135	1157 (aa)	XP_005253647	Q8IY37

Gene Model

Click here to download ENSG00000150990's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000150990	rs150152903	12	124967176	A	Insulin levels in response to oral glucose tolerance test (120 minutes)	29093273	[0.46-1.13] unit increase	0.799	EFO_0004467\|EFO_0004307

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000150990's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000150990	DHX37	73	41.007	ENSG00000005100	DHX33	90	42.085
ENSG00000150990	DHX37	70	39.844	ENSG00000109606	DHX15	79	39.844
ENSG00000150990	DHX37	70	40.945	ENSG00000101452	DHX35	89	40.945
ENSG00000150990	DHX37	73	30.859	ENSG00000089876	DHX32	86	30.859
ENSG00000150990	DHX37	69	42.437	ENSG00000140829	DHX38	68	31.522
ENSG00000150990	DHX37	58	30.418	ENSG00000144045	DQX1	73	30.418
ENSG00000150990	DHX37	70	42.857	ENSG00000067596	DHX8	50	42.975
ENSG00000150990	DHX37	73	39.568	ENSG00000108406	DHX40	97	40.892
ENSG00000150990	DHX37	60	30.537	ENSG00000174953	DHX36	95	34.529
ENSG00000150990	DHX37	72	41.700	ENSG00000204560	DHX16	90	41.463

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000150990	DHX37	94	71.619	ENSAPOG00000021493	dhx37	99	65.757	Acanthochromis_polyacanthus
ENSG00000150990	DHX37	99	85.912	ENSAMEG00000015543	DHX37	99	85.912	Ailuropoda_melanoleuca
ENSG00000150990	DHX37	92	69.482	ENSACIG00000006590	dhx37	94	68.969	Amphilophus_citrinellus
ENSG00000150990	DHX37	94	71.840	ENSAOCG00000015168	dhx37	80	71.041	Amphiprion_ocellaris
ENSG00000150990	DHX37	94	71.508	ENSAPEG00000017509	dhx37	80	70.716	Amphiprion_percula
ENSG00000150990	DHX37	94	70.843	ENSATEG00000020638	dhx37	79	70.065	Anabas_testudineus
ENSG00000150990	DHX37	95	76.039	ENSAPLG00000009562	DHX37	99	71.950	Anas_platyrhynchos
ENSG00000150990	DHX37	95	72.668	ENSACAG00000014642	DHX37	98	68.250	Anolis_carolinensis
ENSG00000150990	DHX37	94	94.574	ENSANAG00000023048	-	100	90.493	Aotus_nancymaae
ENSG00000150990	DHX37	100	89.801	ENSANAG00000034653	-	100	89.455	Aotus_nancymaae
ENSG00000150990	DHX37	93	69.744	ENSACLG00000011192	dhx37	82	68.655	Astatotilapia_calliptera
ENSG00000150990	DHX37	93	72.272	ENSAMXG00000006130	dhx37	79	72.017	Astyanax_mexicanus
ENSG00000150990	DHX37	100	85.751	ENSBTAG00000020414	DHX37	100	85.060	Bos_taurus
ENSG00000150990	DHX37	93	45.545	WBGene00015525	rha-2	80	45.717	Caenorhabditis_elegans
ENSG00000150990	DHX37	100	93.345	ENSCJAG00000021400	DHX37	100	92.999	Callithrix_jacchus
ENSG00000150990	DHX37	99	84.517	ENSCAFG00000006952	DHX37	99	85.048	Canis_familiaris
ENSG00000150990	DHX37	99	84.517	ENSCAFG00020012586	DHX37	99	85.048	Canis_lupus_dingo
ENSG00000150990	DHX37	100	85.862	ENSCHIG00000019152	DHX37	100	84.914	Capra_hircus
ENSG00000150990	DHX37	96	88.985	ENSTSYG00000028383	DHX37	98	88.985	Carlito_syrichta
ENSG00000150990	DHX37	95	86.659	ENSCAPG00000017032	DHX37	97	82.462	Cavia_aperea
ENSG00000150990	DHX37	99	83.205	ENSCPOG00000024675	DHX37	99	82.464	Cavia_porcellus
ENSG00000150990	DHX37	99	93.420	ENSCCAG00000033656	DHX37	99	92.900	Cebus_capucinus
ENSG00000150990	DHX37	100	89.715	ENSCATG00000037537	DHX37	100	89.715	Cercocebus_atys
ENSG00000150990	DHX37	100	81.655	ENSCLAG00000010370	DHX37	100	81.277	Chinchilla_lanigera
ENSG00000150990	DHX37	100	95.506	ENSCSAG00000001977	DHX37	100	95.246	Chlorocebus_sabaeus
ENSG00000150990	DHX37	95	77.462	ENSCPBG00000024888	DHX37	89	77.946	Chrysemys_picta_bellii
ENSG00000150990	DHX37	93	52.108	ENSCING00000001153	-	79	51.695	Ciona_intestinalis
ENSG00000150990	DHX37	94	51.499	ENSCSAVG00000009212	-	84	51.640	Ciona_savignyi
ENSG00000150990	DHX37	89	97.512	ENSCANG00000032521	DHX37	100	97.512	Colobus_angolensis_palliatus
ENSG00000150990	DHX37	99	84.423	ENSCGRG00001014560	Dhx37	99	83.993	Cricetulus_griseus_chok1gshd
ENSG00000150990	DHX37	99	83.993	ENSCGRG00000011701	Dhx37	99	83.147	Cricetulus_griseus_crigri
ENSG00000150990	DHX37	94	57.947	ENSCSEG00000018466	-	98	58.736	Cynoglossus_semilaevis
ENSG00000150990	DHX37	93	71.524	ENSCSEG00000019728	dhx37	79	71.150	Cynoglossus_semilaevis
ENSG00000150990	DHX37	99	65.778	ENSCVAG00000018153	dhx37	99	64.711	Cyprinodon_variegatus
ENSG00000150990	DHX37	93	72.191	ENSDARG00000062612	dhx37	99	64.706	Danio_rerio
ENSG00000150990	DHX37	99	80.017	ENSDNOG00000003434	DHX37	99	79.862	Dasypus_novemcinctus
ENSG00000150990	DHX37	94	87.778	ENSDORG00000012965	Dhx37	100	81.014	Dipodomys_ordii
ENSG00000150990	DHX37	96	48.665	FBgn0001330	kz	79	49.007	Drosophila_melanogaster
ENSG00000150990	DHX37	68	88.596	ENSETEG00000018175	-	68	88.596	Echinops_telfairi
ENSG00000150990	DHX37	94	51.014	ENSEBUG00000013468	dhx37	77	51.371	Eptatretus_burgeri
ENSG00000150990	DHX37	93	89.333	ENSEASG00005013134	DHX37	95	89.405	Equus_asinus_asinus
ENSG00000150990	DHX37	99	85.554	ENSECAG00000007404	DHX37	99	85.640	Equus_caballus
ENSG00000150990	DHX37	95	71.554	ENSELUG00000008988	dhx37	80	71.429	Esox_lucius
ENSG00000150990	DHX37	100	84.695	ENSFCAG00000014583	DHX37	98	89.410	Felis_catus
ENSG00000150990	DHX37	93	76.392	ENSFALG00000009403	DHX37	99	71.962	Ficedula_albicollis
ENSG00000150990	DHX37	93	85.017	ENSFDAG00000009235	DHX37	81	83.262	Fukomys_damarensis
ENSG00000150990	DHX37	95	70.440	ENSFHEG00000018467	dhx37	99	63.458	Fundulus_heteroclitus
ENSG00000150990	DHX37	94	69.546	ENSGMOG00000011509	dhx37	80	68.906	Gadus_morhua
ENSG00000150990	DHX37	93	77.531	ENSGALG00000002964	DHX37	100	71.355	Gallus_gallus
ENSG00000150990	DHX37	93	71.524	ENSGAFG00000000621	dhx37	99	64.833	Gambusia_affinis
ENSG00000150990	DHX37	99	63.903	ENSGACG00000003927	dhx37	99	63.117	Gasterosteus_aculeatus
ENSG00000150990	DHX37	95	75.930	ENSGAGG00000007548	DHX37	100	70.180	Gopherus_agassizii
ENSG00000150990	DHX37	100	98.876	ENSGGOG00000005339	DHX37	100	98.876	Gorilla_gorilla
ENSG00000150990	DHX37	93	69.855	ENSHBUG00000013916	dhx37	82	68.939	Haplochromis_burtoni
ENSG00000150990	DHX37	99	81.810	ENSHGLG00000014066	DHX37	99	80.961	Heterocephalus_glaber_female
ENSG00000150990	DHX37	99	79.623	ENSHGLG00100019104	DHX37	99	78.504	Heterocephalus_glaber_male
ENSG00000150990	DHX37	93	69.633	ENSHCOG00000005836	dhx37	79	69.523	Hippocampus_comes
ENSG00000150990	DHX37	93	71.746	ENSIPUG00000025001	DHX37	99	63.870	Ictalurus_punctatus
ENSG00000150990	DHX37	95	90.022	ENSSTOG00000004784	DHX37	99	85.727	Ictidomys_tridecemlineatus
ENSG00000150990	DHX37	99	82.251	ENSJJAG00000021254	Dhx37	99	81.385	Jaculus_jaculus
ENSG00000150990	DHX37	93	72.414	ENSKMAG00000003517	dhx37	79	71.367	Kryptolebias_marmoratus
ENSG00000150990	DHX37	93	70.189	ENSLBEG00000025303	dhx37	99	63.865	Labrus_bergylta
ENSG00000150990	DHX37	94	74.144	ENSLACG00000012579	DHX37	100	67.639	Latimeria_chalumnae
ENSG00000150990	DHX37	85	72.609	ENSLOCG00000001768	dhx37	78	73.174	Lepisosteus_oculatus
ENSG00000150990	DHX37	99	85.506	ENSLAFG00000004176	DHX37	99	85.420	Loxodonta_africana
ENSG00000150990	DHX37	100	96.975	ENSMFAG00000037879	DHX37	100	96.975	Macaca_fascicularis
ENSG00000150990	DHX37	100	96.802	ENSMMUG00000017902	DHX37	100	96.802	Macaca_mulatta
ENSG00000150990	DHX37	100	92.308	ENSMNEG00000042951	DHX37	99	97.448	Macaca_nemestrina
ENSG00000150990	DHX37	100	92.135	ENSMLEG00000043019	DHX37	100	91.703	Mandrillus_leucophaeus
ENSG00000150990	DHX37	93	71.524	ENSMAMG00000014318	dhx37	79	70.748	Mastacembelus_armatus
ENSG00000150990	DHX37	93	69.744	ENSMZEG00005009802	dhx37	80	69.414	Maylandia_zebra
ENSG00000150990	DHX37	93	76.608	ENSMGAG00000002630	DHX37	84	77.106	Meleagris_gallopavo
ENSG00000150990	DHX37	99	84.867	ENSMAUG00000001526	Dhx37	99	84.238	Mesocricetus_auratus
ENSG00000150990	DHX37	99	86.419	ENSMICG00000005216	DHX37	99	87.155	Microcebus_murinus
ENSG00000150990	DHX37	99	82.155	ENSMOCG00000003143	Dhx37	99	81.638	Microtus_ochrogaster
ENSG00000150990	DHX37	93	70.647	ENSMMOG00000012526	dhx37	99	63.208	Mola_mola
ENSG00000150990	DHX37	86	79.081	ENSMODG00000015681	DHX37	99	74.159	Monodelphis_domestica
ENSG00000150990	DHX37	93	70.222	ENSMALG00000020684	dhx37	79	69.414	Monopterus_albus
ENSG00000150990	DHX37	99	83.233	MGP_CAROLIEiJ_G0027766	Dhx37	99	83.362	Mus_caroli
ENSG00000150990	DHX37	99	83.247	ENSMUSG00000029480	Dhx37	99	83.118	Mus_musculus
ENSG00000150990	DHX37	99	83.463	MGP_PahariEiJ_G0024346	Dhx37	99	82.860	Mus_pahari
ENSG00000150990	DHX37	99	83.076	MGP_SPRETEiJ_G0028765	Dhx37	99	82.874	Mus_spretus
ENSG00000150990	DHX37	95	88.792	ENSMPUG00000001400	DHX37	99	83.380	Mustela_putorius_furo
ENSG00000150990	DHX37	95	87.269	ENSNGAG00000014443	Dhx37	99	81.645	Nannospalax_galili
ENSG00000150990	DHX37	93	67.297	ENSNBRG00000019133	dhx37	82	67.606	Neolamprologus_brichardi
ENSG00000150990	DHX37	100	84.183	ENSNLEG00000002551	DHX37	100	84.010	Nomascus_leucogenys
ENSG00000150990	DHX37	86	89.222	ENSMEUG00000005092	DHX37	94	75.292	Notamacropus_eugenii
ENSG00000150990	DHX37	95	83.461	ENSOPRG00000014496	DHX37	99	75.237	Ochotona_princeps
ENSG00000150990	DHX37	100	83.061	ENSODEG00000009929	DHX37	100	82.575	Octodon_degus
ENSG00000150990	DHX37	99	63.786	ENSONIG00000014404	dhx37	80	69.414	Oreochromis_niloticus
ENSG00000150990	DHX37	95	78.821	ENSOANG00000001323	DHX37	82	79.610	Ornithorhynchus_anatinus
ENSG00000150990	DHX37	91	90.467	ENSOCUG00000008090	DHX37	96	90.467	Oryctolagus_cuniculus
ENSG00000150990	DHX37	94	71.064	ENSORLG00000002635	dhx37	99	64.940	Oryzias_latipes
ENSG00000150990	DHX37	94	71.286	ENSORLG00020005608	dhx37	99	65.517	Oryzias_latipes_hni
ENSG00000150990	DHX37	94	71.286	ENSORLG00015015337	dhx37	99	65.000	Oryzias_latipes_hsok
ENSG00000150990	DHX37	94	70.939	ENSOMEG00000000674	dhx37	80	70.716	Oryzias_melastigma
ENSG00000150990	DHX37	99	88.382	ENSOGAG00000010508	DHX37	100	88.124	Otolemur_garnettii
ENSG00000150990	DHX37	83	85.285	ENSOARG00000017866	-	97	84.440	Ovis_aries
ENSG00000150990	DHX37	100	99.309	ENSPPAG00000013771	DHX37	100	99.309	Pan_paniscus
ENSG00000150990	DHX37	96	87.513	ENSPPRG00000005144	DHX37	98	87.773	Panthera_pardus
ENSG00000150990	DHX37	88	82.429	ENSPTIG00000001223	DHX37	100	82.429	Panthera_tigris_altaica
ENSG00000150990	DHX37	100	99.395	ENSPTRG00000050780	DHX37	100	99.395	Pan_troglodytes
ENSG00000150990	DHX37	100	96.543	ENSPANG00000011473	DHX37	100	96.543	Papio_anubis
ENSG00000150990	DHX37	93	68.820	ENSPKIG00000024671	dhx37	79	67.570	Paramormyrops_kingsleyae
ENSG00000150990	DHX37	95	75.847	ENSPSIG00000003211	DHX37	88	77.714	Pelodiscus_sinensis
ENSG00000150990	DHX37	94	68.212	ENSPMGG00000018379	dhx37	96	68.261	Periophthalmus_magnuspinnatus
ENSG00000150990	DHX37	99	82.220	ENSPEMG00000001822	Dhx37	99	81.440	Peromyscus_maniculatus_bairdii
ENSG00000150990	DHX37	99	75.410	ENSPCIG00000019185	DHX37	99	75.074	Phascolarctos_cinereus
ENSG00000150990	DHX37	94	70.621	ENSPFOG00000012138	dhx37	79	70.174	Poecilia_formosa
ENSG00000150990	DHX37	94	70.953	ENSPLAG00000017487	dhx37	79	70.390	Poecilia_latipinna
ENSG00000150990	DHX37	94	70.732	ENSPMEG00000004040	dhx37	82	70.282	Poecilia_mexicana
ENSG00000150990	DHX37	94	71.619	ENSPREG00000011504	dhx37	79	71.150	Poecilia_reticulata
ENSG00000150990	DHX37	100	94.814	ENSPPYG00000005106	DHX37	100	94.814	Pongo_abelii
ENSG00000150990	DHX37	95	81.446	ENSPCAG00000008968	DHX37	99	79.947	Procavia_capensis
ENSG00000150990	DHX37	99	88.052	ENSPCOG00000027512	DHX37	99	87.965	Propithecus_coquereli
ENSG00000150990	DHX37	99	85.035	ENSPVAG00000008669	DHX37	99	83.907	Pteropus_vampyrus
ENSG00000150990	DHX37	93	69.299	ENSPNYG00000008298	dhx37	82	68.980	Pundamilia_nyererei
ENSG00000150990	DHX37	93	72.111	ENSPNAG00000007771	dhx37	79	71.475	Pygocentrus_nattereri
ENSG00000150990	DHX37	99	84.152	ENSRNOG00000022171	Dhx37	99	83.807	Rattus_norvegicus
ENSG00000150990	DHX37	100	96.370	ENSRBIG00000043457	DHX37	100	96.370	Rhinopithecus_bieti
ENSG00000150990	DHX37	100	96.283	ENSRROG00000041401	DHX37	100	96.283	Rhinopithecus_roxellana
ENSG00000150990	DHX37	79	42.509	YMR128W	ECM16	62	43.067	Saccharomyces_cerevisiae
ENSG00000150990	DHX37	100	92.913	ENSSBOG00000026565	DHX37	100	92.567	Saimiri_boliviensis_boliviensis
ENSG00000150990	DHX37	93	72.747	ENSSFOG00015013932	dhx37	99	65.974	Scleropages_formosus
ENSG00000150990	DHX37	94	70.732	ENSSMAG00000006189	dhx37	100	63.896	Scophthalmus_maximus
ENSG00000150990	DHX37	93	70.745	ENSSDUG00000002265	dhx37	79	69.957	Seriola_dumerili
ENSG00000150990	DHX37	93	70.510	ENSSLDG00000003710	dhx37	99	63.297	Seriola_lalandi_dorsalis
ENSG00000150990	DHX37	95	75.904	ENSSPUG00000013313	DHX37	99	71.609	Sphenodon_punctatus
ENSG00000150990	DHX37	93	71.524	ENSSPAG00000015538	dhx37	80	70.607	Stegastes_partitus
ENSG00000150990	DHX37	100	86.375	ENSSSCG00000009758	DHX37	100	85.825	Sus_scrofa
ENSG00000150990	DHX37	93	71.444	ENSTGUG00000004953	-	100	67.560	Taeniopygia_guttata
ENSG00000150990	DHX37	84	70.297	ENSTRUG00000016466	dhx37	95	69.434	Takifugu_rubripes
ENSG00000150990	DHX37	100	64.061	ENSTNIG00000015925	dhx37	80	70.874	Tetraodon_nigroviridis
ENSG00000150990	DHX37	64	92.000	ENSTBEG00000001651	-	70	92.000	Tupaia_belangeri
ENSG00000150990	DHX37	90	82.927	ENSTTRG00000001648	DHX37	90	82.927	Tursiops_truncatus
ENSG00000150990	DHX37	100	86.379	ENSUAMG00000003979	DHX37	100	85.936	Ursus_americanus
ENSG00000150990	DHX37	95	89.836	ENSUMAG00000000800	DHX37	100	85.661	Ursus_maritimus
ENSG00000150990	DHX37	93	94.052	ENSVVUG00000025832	DHX37	95	86.015	Vulpes_vulpes
ENSG00000150990	DHX37	95	71.460	ENSXETG00000001202	dhx37	97	72.048	Xenopus_tropicalis
ENSG00000150990	DHX37	93	71.079	ENSXCOG00000002147	dhx37	79	70.390	Xiphophorus_couchianus
ENSG00000150990	DHX37	93	71.190	ENSXMAG00000014623	dhx37	79	70.607	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0034459	ATP-dependent 3'-5' RNA helicase activity	21873635.	IBA	Function