EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000151014 (Gene tree)
Gene ID: 25819
Gene Symbol: NOCT
Alias: CCR4L|Ccr4c|NOC|CCRN4L
Full Name: nocturnin
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 30,181 bases
Position: chr4:139,015,759-139,045,939
Accession: 14254
RBP type: canonical RBP
Summary: The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000280614	Exo_endo_phos	PF03372.23	9.2e-24	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18419273	Biological clocks and the coordination theory of RNA operons and regulons.	Cold Spring Harb Symp Quant Biol	2007	Keene JD	doi: 10.1101/sqb.2007.72.013.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000630479	NOCT-203	1572	-	ENSP00000486546	167 (aa)	-	Q8WTX0
ENST00000280614	NOCT-201	1952	-	ENSP00000280614	431 (aa)	-	Q9UK39
ENST00000515616	NOCT-202	739	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000151014's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000151014	rs938836	4	139018499	G	Chronotype	30696823		1.0214263	EFO_0008328

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000151014's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000151014	NOCT	86	60.677	ENSAPOG00000016421	nocta	83	61.111	Acanthochromis_polyacanthus
ENSG00000151014	NOCT	84	61.351	ENSAPOG00000005454	noctb	99	61.351	Acanthochromis_polyacanthus
ENSG00000151014	NOCT	87	95.503	ENSAMEG00000011061	NOCT	96	95.405	Ailuropoda_melanoleuca
ENSG00000151014	NOCT	75	64.048	ENSACIG00000013054	noctb	80	64.048	Amphilophus_citrinellus
ENSG00000151014	NOCT	87	60.567	ENSAOCG00000014089	nocta	84	61.376	Amphiprion_ocellaris
ENSG00000151014	NOCT	84	58.656	ENSAOCG00000005363	noctb	99	58.656	Amphiprion_ocellaris
ENSG00000151014	NOCT	87	60.724	ENSAPEG00000018097	nocta	84	61.538	Amphiprion_percula
ENSG00000151014	NOCT	84	58.915	ENSAPEG00000015529	noctb	99	58.915	Amphiprion_percula
ENSG00000151014	NOCT	83	62.667	ENSATEG00000015612	nocta	91	62.667	Anabas_testudineus
ENSG00000151014	NOCT	83	58.747	ENSATEG00000022975	noctb	99	59.008	Anabas_testudineus
ENSG00000151014	NOCT	85	80.978	ENSACAG00000001961	NOCT	98	80.978	Anolis_carolinensis
ENSG00000151014	NOCT	99	97.209	ENSANAG00000009701	NOCT	99	97.209	Aotus_nancymaae
ENSG00000151014	NOCT	84	60.383	ENSACLG00000010843	noctb	97	60.383	Astatotilapia_calliptera
ENSG00000151014	NOCT	98	56.629	ENSAMXG00000002383	nocta	83	62.973	Astyanax_mexicanus
ENSG00000151014	NOCT	99	91.784	ENSBTAG00000005998	NOCT	99	92.506	Bos_taurus
ENSG00000151014	NOCT	99	97.442	ENSCJAG00000003158	NOCT	99	97.442	Callithrix_jacchus
ENSG00000151014	NOCT	84	97.253	ENSCAFG00000003725	NOCT	99	97.253	Canis_familiaris
ENSG00000151014	NOCT	99	92.326	ENSCAFG00020020824	NOCT	99	92.093	Canis_lupus_dingo
ENSG00000151014	NOCT	99	92.019	ENSCHIG00000023612	NOCT	80	92.740	Capra_hircus
ENSG00000151014	NOCT	69	86.047	ENSTSYG00000032273	NOCT	96	86.047	Carlito_syrichta
ENSG00000151014	NOCT	85	96.448	ENSCAPG00000005005	NOCT	94	96.448	Cavia_aperea
ENSG00000151014	NOCT	99	93.208	ENSCPOG00000003827	NOCT	99	93.208	Cavia_porcellus
ENSG00000151014	NOCT	99	97.674	ENSCCAG00000022628	NOCT	99	97.674	Cebus_capucinus
ENSG00000151014	NOCT	90	73.385	ENSCATG00000012533	-	92	73.243	Cercocebus_atys
ENSG00000151014	NOCT	99	98.140	ENSCATG00000041737	-	99	98.140	Cercocebus_atys
ENSG00000151014	NOCT	99	86.854	ENSCLAG00000003384	NOCT	99	86.854	Chinchilla_lanigera
ENSG00000151014	NOCT	84	99.451	ENSCSAG00000003545	NOCT	99	99.451	Chlorocebus_sabaeus
ENSG00000151014	NOCT	85	95.628	ENSCHOG00000004354	NOCT	99	95.628	Choloepus_hoffmanni
ENSG00000151014	NOCT	99	76.667	ENSCPBG00000027624	NOCT	91	76.667	Chrysemys_picta_bellii
ENSG00000151014	NOCT	99	98.837	ENSCANG00000031969	-	99	98.837	Colobus_angolensis_palliatus
ENSG00000151014	NOCT	90	84.456	ENSCANG00000039017	-	95	85.095	Colobus_angolensis_palliatus
ENSG00000151014	NOCT	99	90.000	ENSCGRG00001021050	Noct	99	89.767	Cricetulus_griseus_chok1gshd
ENSG00000151014	NOCT	88	92.328	ENSCGRG00000014052	Noct	96	93.207	Cricetulus_griseus_crigri
ENSG00000151014	NOCT	84	59.677	ENSCSEG00000014449	noctb	97	59.677	Cynoglossus_semilaevis
ENSG00000151014	NOCT	99	56.689	ENSCVAG00000001857	nocta	98	56.009	Cyprinodon_variegatus
ENSG00000151014	NOCT	84	59.103	ENSCVAG00000001093	noctb	99	59.103	Cyprinodon_variegatus
ENSG00000151014	NOCT	98	58.161	ENSDARG00000077726	nocta	98	58.161	Danio_rerio
ENSG00000151014	NOCT	83	65.135	ENSDARG00000078525	noctb	99	65.135	Danio_rerio
ENSG00000151014	NOCT	99	92.575	ENSDNOG00000036912	NOCT	99	93.271	Dasypus_novemcinctus
ENSG00000151014	NOCT	87	87.863	ENSDORG00000000869	Noct	99	90.736	Dipodomys_ordii
ENSG00000151014	NOCT	67	47.727	FBgn0261808	cu	73	47.727	Drosophila_melanogaster
ENSG00000151014	NOCT	99	95.814	ENSEASG00005007871	NOCT	99	95.814	Equus_asinus_asinus
ENSG00000151014	NOCT	99	95.814	ENSECAG00000022676	NOCT	99	95.814	Equus_caballus
ENSG00000151014	NOCT	55	88.085	ENSEEUG00000010558	-	100	88.085	Erinaceus_europaeus
ENSG00000151014	NOCT	63	87.868	ENSEEUG00000013650	-	100	87.868	Erinaceus_europaeus
ENSG00000151014	NOCT	85	59.481	ENSELUG00000011415	noctb	87	59.481	Esox_lucius
ENSG00000151014	NOCT	91	55.738	ENSELUG00000002538	nocta	98	61.995	Esox_lucius
ENSG00000151014	NOCT	99	96.279	ENSFCAG00000030026	NOCT	99	96.279	Felis_catus
ENSG00000151014	NOCT	84	84.066	ENSFALG00000004876	NOCT	99	84.066	Ficedula_albicollis
ENSG00000151014	NOCT	64	96.715	ENSFDAG00000018163	NOCT	99	96.715	Fukomys_damarensis
ENSG00000151014	NOCT	84	57.254	ENSFHEG00000013623	noctb	99	57.513	Fundulus_heteroclitus
ENSG00000151014	NOCT	86	61.558	ENSFHEG00000005067	nocta	85	61.968	Fundulus_heteroclitus
ENSG00000151014	NOCT	85	83.924	ENSGALG00000032957	NOCT	95	83.924	Gallus_gallus
ENSG00000151014	NOCT	86	61.155	ENSGAFG00000019587	nocta	83	62.500	Gambusia_affinis
ENSG00000151014	NOCT	84	60.209	ENSGAFG00000015232	noctb	99	60.471	Gambusia_affinis
ENSG00000151014	NOCT	84	85.440	ENSGAGG00000004412	NOCT	99	85.440	Gopherus_agassizii
ENSG00000151014	NOCT	100	81.019	ENSGGOG00000028610	-	85	98.921	Gorilla_gorilla
ENSG00000151014	NOCT	76	63.554	ENSHBUG00000001687	noctb	91	63.554	Haplochromis_burtoni
ENSG00000151014	NOCT	99	85.023	ENSHGLG00000019383	NOCT	99	85.023	Heterocephalus_glaber_female
ENSG00000151014	NOCT	87	95.479	ENSHGLG00100012584	NOCT	98	96.206	Heterocephalus_glaber_male
ENSG00000151014	NOCT	98	56.335	ENSHCOG00000005299	nocta	99	56.335	Hippocampus_comes
ENSG00000151014	NOCT	84	58.760	ENSHCOG00000013999	noctb	100	58.760	Hippocampus_comes
ENSG00000151014	NOCT	98	54.795	ENSIPUG00000017932	Ccrn4l	98	55.708	Ictalurus_punctatus
ENSG00000151014	NOCT	85	97.268	ENSSTOG00000014818	NOCT	99	97.268	Ictidomys_tridecemlineatus
ENSG00000151014	NOCT	99	90.069	ENSJJAG00000019776	Noct	99	89.376	Jaculus_jaculus
ENSG00000151014	NOCT	84	59.126	ENSKMAG00000019996	noctb	81	59.126	Kryptolebias_marmoratus
ENSG00000151014	NOCT	90	59.198	ENSKMAG00000001493	nocta	85	62.895	Kryptolebias_marmoratus
ENSG00000151014	NOCT	84	54.545	ENSLBEG00000021526	-	98	54.545	Labrus_bergylta
ENSG00000151014	NOCT	84	60.892	ENSLBEG00000017977	noctb	99	61.376	Labrus_bergylta
ENSG00000151014	NOCT	87	61.440	ENSLBEG00000024022	nocta	82	62.533	Labrus_bergylta
ENSG00000151014	NOCT	99	69.058	ENSLACG00000015874	NOCT	99	67.713	Latimeria_chalumnae
ENSG00000151014	NOCT	99	67.195	ENSLOCG00000010593	nocta	99	67.195	Lepisosteus_oculatus
ENSG00000151014	NOCT	85	96.458	ENSLAFG00000017184	NOCT	99	96.458	Loxodonta_africana
ENSG00000151014	NOCT	99	98.605	ENSMFAG00000002713	-	99	98.605	Macaca_fascicularis
ENSG00000151014	NOCT	94	77.419	ENSMFAG00000045037	-	98	74.146	Macaca_fascicularis
ENSG00000151014	NOCT	90	82.642	ENSMMUG00000030791	-	99	76.271	Macaca_mulatta
ENSG00000151014	NOCT	84	99.725	ENSMMUG00000004983	-	99	99.725	Macaca_mulatta
ENSG00000151014	NOCT	90	73.196	ENSMNEG00000007123	-	97	73.196	Macaca_nemestrina
ENSG00000151014	NOCT	99	98.605	ENSMNEG00000042407	-	99	98.605	Macaca_nemestrina
ENSG00000151014	NOCT	84	73.973	ENSMLEG00000029801	-	99	73.973	Mandrillus_leucophaeus
ENSG00000151014	NOCT	99	98.605	ENSMLEG00000040699	-	99	98.605	Mandrillus_leucophaeus
ENSG00000151014	NOCT	84	60.154	ENSMAMG00000006732	noctb	99	60.154	Mastacembelus_armatus
ENSG00000151014	NOCT	87	61.323	ENSMAMG00000002501	nocta	87	62.304	Mastacembelus_armatus
ENSG00000151014	NOCT	84	59.055	ENSMZEG00005011616	noctb	97	59.055	Maylandia_zebra
ENSG00000151014	NOCT	85	84.196	ENSMGAG00000002778	NOCT	95	84.196	Meleagris_gallopavo
ENSG00000151014	NOCT	84	92.582	ENSMAUG00000013688	Noct	99	92.582	Mesocricetus_auratus
ENSG00000151014	NOCT	84	96.978	ENSMICG00000046478	NOCT	99	96.978	Microcebus_murinus
ENSG00000151014	NOCT	99	86.744	ENSMOCG00000013676	Noct	99	87.442	Microtus_ochrogaster
ENSG00000151014	NOCT	84	57.143	ENSMMOG00000006622	noctb	99	57.143	Mola_mola
ENSG00000151014	NOCT	84	61.358	ENSMMOG00000001406	nocta	96	61.619	Mola_mola
ENSG00000151014	NOCT	99	80.357	ENSMODG00000000087	NOCT	99	81.473	Monodelphis_domestica
ENSG00000151014	NOCT	92	57.583	ENSMALG00000000329	nocta	81	61.097	Monopterus_albus
ENSG00000151014	NOCT	84	59.358	ENSMALG00000021977	noctb	99	59.358	Monopterus_albus
ENSG00000151014	NOCT	99	90.610	MGP_CAROLIEiJ_G0024971	Noct	99	90.610	Mus_caroli
ENSG00000151014	NOCT	99	90.845	ENSMUSG00000023087	Noct	99	95.278	Mus_musculus
ENSG00000151014	NOCT	99	91.080	MGP_PahariEiJ_G0026412	Noct	99	91.080	Mus_pahari
ENSG00000151014	NOCT	99	90.845	MGP_SPRETEiJ_G0025906	Noct	99	90.845	Mus_spretus
ENSG00000151014	NOCT	84	98.352	ENSMPUG00000016137	NOCT	99	98.352	Mustela_putorius_furo
ENSG00000151014	NOCT	86	90.566	ENSMLUG00000009023	NOCT	99	90.786	Myotis_lucifugus
ENSG00000151014	NOCT	84	94.780	ENSNGAG00000010135	Noct	99	94.780	Nannospalax_galili
ENSG00000151014	NOCT	84	72.414	ENSNBRG00000017964	noctb	82	60.929	Neolamprologus_brichardi
ENSG00000151014	NOCT	85	99.726	ENSNLEG00000014018	NOCT	100	99.726	Nomascus_leucogenys
ENSG00000151014	NOCT	85	92.350	ENSMEUG00000009500	NOCT	99	92.350	Notamacropus_eugenii
ENSG00000151014	NOCT	99	92.791	ENSOPRG00000003306	NOCT	99	92.791	Ochotona_princeps
ENSG00000151014	NOCT	99	92.791	ENSODEG00000003057	NOCT	99	92.791	Octodon_degus
ENSG00000151014	NOCT	85	59.631	ENSONIG00000003358	noctb	99	59.580	Oreochromis_niloticus
ENSG00000151014	NOCT	84	79.837	ENSOANG00000013761	NOCT	84	79.837	Ornithorhynchus_anatinus
ENSG00000151014	NOCT	99	95.349	ENSOCUG00000005465	NOCT	99	95.349	Oryctolagus_cuniculus
ENSG00000151014	NOCT	85	59.103	ENSORLG00000002100	noctb	89	59.309	Oryzias_latipes
ENSG00000151014	NOCT	84	59.517	ENSORLG00020013826	noctb	99	59.517	Oryzias_latipes_hni
ENSG00000151014	NOCT	88	60.513	ENSORLG00015019270	nocta	85	61.622	Oryzias_latipes_hsok
ENSG00000151014	NOCT	90	57.805	ENSORLG00015013405	noctb	97	57.805	Oryzias_latipes_hsok
ENSG00000151014	NOCT	85	60.160	ENSOMEG00000021625	noctb	91	60.541	Oryzias_melastigma
ENSG00000151014	NOCT	88	60.358	ENSOMEG00000010743	nocta	85	62.060	Oryzias_melastigma
ENSG00000151014	NOCT	99	93.953	ENSOGAG00000008532	NOCT	99	92.791	Otolemur_garnettii
ENSG00000151014	NOCT	90	91.237	ENSOARG00000014103	NOCT	99	88.943	Ovis_aries
ENSG00000151014	NOCT	86	99.459	ENSPPAG00000042856	NOCT	100	99.726	Pan_paniscus
ENSG00000151014	NOCT	99	96.279	ENSPPRG00000009488	NOCT	99	96.279	Panthera_pardus
ENSG00000151014	NOCT	85	97.814	ENSPTIG00000008672	NOCT	99	97.802	Panthera_tigris_altaica
ENSG00000151014	NOCT	100	99.536	ENSPTRG00000016448	NOCT	100	99.726	Pan_troglodytes
ENSG00000151014	NOCT	99	98.605	ENSPANG00000029213	NOCT	99	98.605	Papio_anubis
ENSG00000151014	NOCT	84	61.944	ENSPKIG00000013368	NOCT	99	61.944	Paramormyrops_kingsleyae
ENSG00000151014	NOCT	99	60.920	ENSPKIG00000022066	nocta	99	60.920	Paramormyrops_kingsleyae
ENSG00000151014	NOCT	99	75.610	ENSPSIG00000010338	NOCT	91	75.610	Pelodiscus_sinensis
ENSG00000151014	NOCT	83	61.559	ENSPMGG00000019525	noctb	99	61.559	Periophthalmus_magnuspinnatus
ENSG00000151014	NOCT	85	61.290	ENSPMGG00000004558	nocta	88	61.290	Periophthalmus_magnuspinnatus
ENSG00000151014	NOCT	84	94.505	ENSPEMG00000016096	Noct	99	94.505	Peromyscus_maniculatus_bairdii
ENSG00000151014	NOCT	84	48.919	ENSPMAG00000002990	nocta	99	48.919	Petromyzon_marinus
ENSG00000151014	NOCT	99	82.599	ENSPCIG00000027121	NOCT	99	82.159	Phascolarctos_cinereus
ENSG00000151014	NOCT	86	61.299	ENSPFOG00000004800	nocta	83	62.234	Poecilia_formosa
ENSG00000151014	NOCT	84	59.375	ENSPFOG00000015717	noctb	99	59.896	Poecilia_formosa
ENSG00000151014	NOCT	84	62.634	ENSPLAG00000004749	nocta	99	62.634	Poecilia_latipinna
ENSG00000151014	NOCT	84	59.375	ENSPLAG00000016228	noctb	99	59.896	Poecilia_latipinna
ENSG00000151014	NOCT	84	58.854	ENSPMEG00000019690	noctb	99	59.375	Poecilia_mexicana
ENSG00000151014	NOCT	84	62.634	ENSPMEG00000008265	nocta	90	63.200	Poecilia_mexicana
ENSG00000151014	NOCT	86	61.780	ENSPREG00000006876	nocta	83	63.032	Poecilia_reticulata
ENSG00000151014	NOCT	84	58.594	ENSPREG00000001623	noctb	99	59.115	Poecilia_reticulata
ENSG00000151014	NOCT	100	99.304	ENSPPYG00000015067	NOCT	100	99.304	Pongo_abelii
ENSG00000151014	NOCT	99	83.023	ENSPCAG00000016793	NOCT	99	83.023	Procavia_capensis
ENSG00000151014	NOCT	99	94.037	ENSPCOG00000013805	NOCT	99	94.725	Propithecus_coquereli
ENSG00000151014	NOCT	99	93.488	ENSPVAG00000017841	NOCT	99	92.791	Pteropus_vampyrus
ENSG00000151014	NOCT	84	60.109	ENSPNYG00000003447	noctb	97	60.109	Pundamilia_nyererei
ENSG00000151014	NOCT	98	57.045	ENSPNAG00000029426	nocta	82	63.661	Pygocentrus_nattereri
ENSG00000151014	NOCT	99	89.535	ENSRNOG00000010799	Noct	99	90.233	Rattus_norvegicus
ENSG00000151014	NOCT	93	77.114	ENSRBIG00000040138	-	92	73.621	Rhinopithecus_bieti
ENSG00000151014	NOCT	99	98.837	ENSRBIG00000032388	-	99	98.837	Rhinopithecus_bieti
ENSG00000151014	NOCT	99	98.837	ENSRROG00000032107	-	99	98.837	Rhinopithecus_roxellana
ENSG00000151014	NOCT	93	86.070	ENSRROG00000043125	-	94	89.973	Rhinopithecus_roxellana
ENSG00000151014	NOCT	88	98.421	ENSSBOG00000022743	NOCT	99	98.421	Saimiri_boliviensis_boliviensis
ENSG00000151014	NOCT	88	91.029	ENSSHAG00000004440	NOCT	93	92.916	Sarcophilus_harrisii
ENSG00000151014	NOCT	85	68.022	ENSSFOG00015024047	NOCT	93	68.022	Scleropages_formosus
ENSG00000151014	NOCT	99	58.296	ENSSFOG00015019938	noctb	99	64.499	Scleropages_formosus
ENSG00000151014	NOCT	99	55.385	ENSSMAG00000015100	nocta	89	56.279	Scophthalmus_maximus
ENSG00000151014	NOCT	85	60.106	ENSSMAG00000012233	noctb	89	60.322	Scophthalmus_maximus
ENSG00000151014	NOCT	98	59.101	ENSSDUG00000000870	nocta	99	58.652	Seriola_dumerili
ENSG00000151014	NOCT	84	61.622	ENSSDUG00000019799	noctb	99	62.432	Seriola_dumerili
ENSG00000151014	NOCT	85	59.694	ENSSLDG00000008012	noctb	97	59.847	Seriola_lalandi_dorsalis
ENSG00000151014	NOCT	98	59.101	ENSSLDG00000007584	nocta	99	58.652	Seriola_lalandi_dorsalis
ENSG00000151014	NOCT	84	68.044	ENSSARG00000008892	NOCT	99	68.044	Sorex_araneus
ENSG00000151014	NOCT	91	81.633	ENSSPUG00000008160	NOCT	93	84.553	Sphenodon_punctatus
ENSG00000151014	NOCT	84	62.973	ENSSPAG00000010999	noctb	99	62.973	Stegastes_partitus
ENSG00000151014	NOCT	87	61.675	ENSSPAG00000023537	nocta	87	62.240	Stegastes_partitus
ENSG00000151014	NOCT	99	92.506	ENSSSCG00000024596	NOCT	100	95.014	Sus_scrofa
ENSG00000151014	NOCT	85	83.651	ENSTGUG00000014883	-	99	83.651	Taeniopygia_guttata
ENSG00000151014	NOCT	85	83.651	ENSTGUG00000002465	-	99	83.424	Taeniopygia_guttata
ENSG00000151014	NOCT	83	60.976	ENSTRUG00000014977	noctb	100	60.976	Takifugu_rubripes
ENSG00000151014	NOCT	97	56.376	ENSTRUG00000004981	nocta	90	62.599	Takifugu_rubripes
ENSG00000151014	NOCT	84	60.317	ENSTNIG00000014249	nocta	98	60.317	Tetraodon_nigroviridis
ENSG00000151014	NOCT	76	61.585	ENSTNIG00000012346	noctb	99	61.585	Tetraodon_nigroviridis
ENSG00000151014	NOCT	64	97.464	ENSTBEG00000009092	NOCT	75	97.464	Tupaia_belangeri
ENSG00000151014	NOCT	56	95.714	ENSTTRG00000013558	NOCT	61	95.714	Tursiops_truncatus
ENSG00000151014	NOCT	99	94.419	ENSUAMG00000011467	NOCT	99	94.419	Ursus_americanus
ENSG00000151014	NOCT	84	95.879	ENSUMAG00000014943	NOCT	99	95.879	Ursus_maritimus
ENSG00000151014	NOCT	99	91.183	ENSVPAG00000003667	NOCT	99	91.183	Vicugna_pacos
ENSG00000151014	NOCT	87	95.989	ENSVVUG00000021461	NOCT	99	97.527	Vulpes_vulpes
ENSG00000151014	NOCT	86	78.495	ENSXETG00000016899	noct	80	78.689	Xenopus_tropicalis
ENSG00000151014	NOCT	84	62.599	ENSXCOG00000013730	nocta	86	62.933	Xiphophorus_couchianus
ENSG00000151014	NOCT	84	61.141	ENSXCOG00000012036	noctb	99	62.060	Xiphophorus_couchianus
ENSG00000151014	NOCT	86	61.240	ENSXMAG00000029143	NOCT	88	62.234	Xiphophorus_maculatus
ENSG00000151014	NOCT	84	59.115	ENSXMAG00000017762	noctb	99	59.375	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	-	IEA	Process
GO:0000932	P-body	-	IEA	Component
GO:0003729	mRNA binding	-	ISS	Function
GO:0004535	poly(A)-specific ribonuclease activity	-	ISS	Function
GO:0005634	nucleus	-	ISS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	-	ISS	Component
GO:0006366	transcription by RNA polymerase II	10521507.	TAS	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0007623	circadian rhythm	-	TAS	Process
GO:0009991	response to extracellular stimulus	-	ISS	Process
GO:0010629	negative regulation of gene expression	-	ISS	Process
GO:0032496	response to lipopolysaccharide	-	ISS	Process
GO:0032922	circadian regulation of gene expression	-	ISS	Process
GO:0033962	cytoplasmic mRNA processing body assembly	-	IEA	Process
GO:0042752	regulation of circadian rhythm	-	ISS	Process
GO:0045600	positive regulation of fat cell differentiation	-	ISS	Process
GO:0045668	negative regulation of osteoblast differentiation	-	ISS	Process
GO:0045995	regulation of embryonic development	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0048255	mRNA stabilization	-	ISS	Process
GO:0048471	perinuclear region of cytoplasm	-	ISS	Component
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	-	IEA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
16821125	RANKL-induced CCL22/macrophage-derived chemokine produced from osteoclasts potentially promotes the bone metastasis of lung cancer expressing its receptor CCR4.	Clin Exp Metastasis	2006	Nakamura ES	-
24821610	Association between CLOCK, PER3 and CCRN4L with nonsmall cell lung cancer in Brazilian patients.	Mol Med Rep	2014 Jul	Couto P	doi: 10.3892/mmr.2014.2224

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr4	139045270	Nonsense_Mutation	novel	W364*	0.29	Exo_endo_phos
BLCA	chr4	139043117	Silent	rs201273091	L78L	0.31
BLCA	chr4	139043503	Intron	novel		0.38
BLCA	chr4	139045072	In_Frame_Del	novel	A299_Q300del	0.29	Exo_endo_phos
BLCA	chr4	139045238	Missense_Mutation	NA	D354H	0.23	Exo_endo_phos
BLCA	chr4	139043477	Intron	novel		0.46
BLCA	chr4	139045231	Silent	rs773335755	L351L	0.15
BRCA	chr4	139045153	Missense_Mutation	novel	F325L	0.23	Exo_endo_phos
BRCA	chr4	139045355	Missense_Mutation	rs144899070	D393N	0.1	Exo_endo_phos
BRCA	chr4	139043308	Missense_Mutation	NA	P142L	0.3
CESC	chr4	139045847	3'UTR	novel		0.48
CESC	chr4	139044722	Missense_Mutation	novel	E182K	0.95	Exo_endo_phos
CESC	chr4	139045250	Missense_Mutation	NA	E358K	0.26	Exo_endo_phos
CESC	chr4	139044943	Silent	NA	L255L	0.29
COAD	chr4	139045021	Silent	novel	C281C	0.4
COAD	chr4	139044790	Silent	NA	Q204Q	0.41
COAD	chr4	139043117	Silent	rs201273091	L78L	0.17
COAD	chr4	139045508	3'UTR	novel		0.45
GBM	chr4	139045477	3'UTR	novel		0.31
GBM	chr4	139043300	Silent	novel	T139T	0.07
HNSC	chr4	139044804	Missense_Mutation	novel	R209T	0.15	Exo_endo_phos
HNSC	chr4	139043271	Missense_Mutation	novel	V130M	0.2
HNSC	chr4	139044712	Silent	novel	L178L	0.23
HNSC	chr4	139044853	Silent	novel	L225L	0.35
KIRC	chr4	139044968	Missense_Mutation	NA	Q264E	0.32	Exo_endo_phos
KIRC	chr4	139045023	Missense_Mutation	NA	I282T	0.33	Exo_endo_phos
KIRP	chr4	139044698	Frame_Shift_Del	novel	*E174Gfs9**	0.33	Exo_endo_phos
LIHC	chr4	139044695	Missense_Mutation	novel	E173K	0.27	Exo_endo_phos
LIHC	chr4	139044637	Splice_Site	NA	X154_splice	0.5
LIHC	chr4	139044815	Missense_Mutation	novel	Q213K	0.38	Exo_endo_phos
LUAD	chr4	139043298	Missense_Mutation	novel	T139A	0.07
LUAD	chr4	139045160	Missense_Mutation	novel	E328Q	0.13	Exo_endo_phos
LUSC	chr4	139045085	Missense_Mutation	novel	D303N	0.78	Exo_endo_phos
LUSC	chr4	139045395	Frame_Shift_Del	novel	*S407Tfs4**	0.12
LUSC	chr4	139044956	Silent	rs140314273	L260L	0.24
LUSC	chr4	139045267	Silent	NA	T363T	0.33
LUSC	chr4	139044804	Missense_Mutation	novel	R209T	0.24	Exo_endo_phos
LUSC	chr4	139044787	Missense_Mutation	novel	F203L	0.66	Exo_endo_phos
OV	chr4	139043351	Intron	novel		0.04
OV	chr4	139043353	Intron	novel		0.19
OV	chr4	139043226	Silent	NA	R115R	0.32
OV	chr4	139043355	Intron	novel		0.04
PAAD	chr4	139044889	Silent	novel	A237A	0.07
READ	chr4	139043374	Intron	novel		0.17
SKCM	chr4	139044846	Missense_Mutation	rs757537642	P223L	0.21	Exo_endo_phos
SKCM	chr4	139044796	Silent	rs762609219	L206L	0.33
SKCM	chr4	139044797	Missense_Mutation	novel	L207F	0.33	Exo_endo_phos
STAD	chr4	139044706	Silent	novel	K176K	0.18
STAD	chr4	139045508	3'UTR	novel		0.39
STAD	chr4	139043142	Missense_Mutation	novel	A87P	0.08
STAD	chr4	139043194	Missense_Mutation	NA	P104L	0.27
THCA	chr4	139045418	Missense_Mutation	NA	H414D	0.26
UCEC	chr4	139044771	Missense_Mutation	NA	H198R	0.29	Exo_endo_phos
UCEC	chr4	139043245	Missense_Mutation	NA	R121Q	0.31
UCEC	chr4	139044971	Missense_Mutation	novel	V265M	0.21	Exo_endo_phos
UCEC	chr4	139045061	Missense_Mutation	rs371556362	R295W	0.6	Exo_endo_phos
UCEC	chr4	139043072	Splice_Site	novel	X64_splice	0.4
UCEC	chr4	139044825	Missense_Mutation	novel	F216Y	0.19	Exo_endo_phos
UCEC	chr4	139045067	Nonsense_Mutation	rs769256787	R297*	0.44	Exo_endo_phos
UCEC	chr4	139045732	3'UTR	novel		0.35
UCEC	chr4	139044886	Silent	novel	C236C	0.3
UCEC	chr4	139045070	Missense_Mutation	novel	S298T	0.25	Exo_endo_phos
UCEC	chr4	139045238	Missense_Mutation	NA	D354H	0.15	Exo_endo_phos
UCEC	chr4	139045712	3'UTR	novel		0.21
UCEC	chr4	139044710	Missense_Mutation	novel	L178I	0.41	Exo_endo_phos
UCEC	chr4	139045852	3'UTR	novel		0.11
UCEC	chr4	139044819	Missense_Mutation	novel	G214D	0.38	Exo_endo_phos
UCEC	chr4	139044917	Silent	novel	L247L	0.53
UCEC	chr4	139045579	3'UTR	novel		0.33
UCEC	chr4	139045169	Nonsense_Mutation	novel	E331*	0.1	Exo_endo_phos
UCEC	chr4	139043349	Splice_Region	novel		0.2
UCEC	chr4	139043138	Silent	rs751476555	S85S	0.5
UCEC	chr4	139044863	Missense_Mutation	NA	H229Y	0.27	Exo_endo_phos
UCEC	chr4	139043521	Intron	novel		0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1444	2.13e-13

Survival Analysis

Cancer	P-value	Q-value
THYM	0.049	Kaplan-Meier Survival Analysis
MESO	0.0002	Kaplan-Meier Survival Analysis
HNSC	0.0032	Kaplan-Meier Survival Analysis
PRAD	0.019	Kaplan-Meier Survival Analysis
LUSC	0.0088	Kaplan-Meier Survival Analysis
KIRP	0.0068	Kaplan-Meier Survival Analysis
PCPG	0.024	Kaplan-Meier Survival Analysis
BLCA	0.0012	Kaplan-Meier Survival Analysis
CESC	0.026	Kaplan-Meier Survival Analysis
LAML	0.0073	Kaplan-Meier Survival Analysis
GBM	0.0095	Kaplan-Meier Survival Analysis
DLBC	0.049	Kaplan-Meier Survival Analysis
THCA	0.018	Kaplan-Meier Survival Analysis
LUAD	0.0015	Kaplan-Meier Survival Analysis
UVM	0.00018	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742