EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000151576 (Gene tree)
Gene ID: 79691
Gene Symbol: QTRT2
Alias: FLJ12960|QTRTD1
Full Name: queuine tRNA-ribosyltransferase accessory subunit 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 82,590 bases
Position: chr3:114,005,833-114,088,422
Accession: 25771
RBP type: canonical RBP
Summary: This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000281273	TGT	PF01702.18	7.1e-84	1	1
ENSP00000420682	TGT	PF01702.18	7.9e-84	1	1
ENSP00000419169	TGT	PF01702.18	7.5e-74	1	1
ENSP00000418056	TGT	PF01702.18	8.4e-71	1	1
ENSP00000420806	TGT	PF01702.18	1.5e-13	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000495782	QTRT2-216	823	-	-	- (aa)	-	-
ENST00000281273	QTRT2-201	4023	-	ENSP00000281273	415 (aa)	-	Q9H974
ENST00000467703	QTRT2-207	3060	-	-	- (aa)	-	-
ENST00000483272	QTRT2-211	575	-	-	- (aa)	-	-
ENST00000479882	QTRT2-209	1196	XM_005247769	ENSP00000418056	292 (aa)	XP_005247826	Q9H974
ENST00000466050	QTRT2-205	583	-	-	- (aa)	-	-
ENST00000472599	QTRT2-208	680	-	ENSP00000420806	167 (aa)	-	C9JJ71
ENST00000466870	QTRT2-206	522	-	-	- (aa)	-	-
ENST00000482307	QTRT2-210	449	-	ENSP00000419655	145 (aa)	-	C9K0B6
ENST00000493014	QTRT2-215	1046	-	ENSP00000419169	309 (aa)	-	Q9H974
ENST00000490183	QTRT2-214	507	-	-	- (aa)	-	-
ENST00000460163	QTRT2-202	614	-	-	- (aa)	-	-
ENST00000488665	QTRT2-213	664	-	-	- (aa)	-	-
ENST00000462869	QTRT2-203	399	-	-	- (aa)	-	-
ENST00000462966	QTRT2-204	881	-	ENSP00000418180	9 (aa)	-	A0A1D5RMQ5
ENST00000485050	QTRT2-212	3844	XM_011513137	ENSP00000420682	427 (aa)	XP_011511439	Q9H974

Gene Model

Click here to download ENSG00000151576's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000151576	Platelet Function Tests	1.6045200E-005	-
ENSG00000151576	Platelet Function Tests	2.3611100E-005	-
ENSG00000151576	Platelet Function Tests	2.7597600E-005	-
ENSG00000151576	Platelet Function Tests	1.5094000E-005	-
ENSG00000151576	Personality	6E-6	23903073

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000151576's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000151576	QTRT2	97	75.000	ENSAPOG00000001940	qtrt2	97	57.794	Acanthochromis_polyacanthus
ENSG00000151576	QTRT2	100	91.667	ENSAMEG00000005349	-	100	90.802	Ailuropoda_melanoleuca
ENSG00000151576	QTRT2	92	76.471	ENSAMEG00000017447	-	100	75.433	Ailuropoda_melanoleuca
ENSG00000151576	QTRT2	98	57.491	ENSACIG00000021458	qtrt2	97	56.448	Amphilophus_citrinellus
ENSG00000151576	QTRT2	97	75.000	ENSAOCG00000008581	qtrt2	99	57.729	Amphiprion_ocellaris
ENSG00000151576	QTRT2	97	75.000	ENSAPEG00000019285	qtrt2	99	57.488	Amphiprion_percula
ENSG00000151576	QTRT2	99	60.900	ENSATEG00000009688	qtrt2	98	59.564	Anabas_testudineus
ENSG00000151576	QTRT2	100	84.848	ENSAPLG00000001359	QTRT2	99	64.010	Anas_platyrhynchos
ENSG00000151576	QTRT2	100	87.879	ENSACAG00000009920	QTRT2	98	67.874	Anolis_carolinensis
ENSG00000151576	QTRT2	100	96.918	ENSANAG00000028433	QTRT2	100	96.386	Aotus_nancymaae
ENSG00000151576	QTRT2	99	55.476	ENSACLG00000026851	qtrt2	97	55.582	Astatotilapia_calliptera
ENSG00000151576	QTRT2	100	66.667	ENSAMXG00000038440	qtrt2	99	55.769	Astyanax_mexicanus
ENSG00000151576	QTRT2	100	91.807	ENSBTAG00000004977	QTRT2	100	91.807	Bos_taurus
ENSG00000151576	QTRT2	100	96.918	ENSCJAG00000009294	QTRT2	100	96.627	Callithrix_jacchus
ENSG00000151576	QTRT2	100	91.807	ENSCAFG00000010759	QTRT2	100	91.807	Canis_familiaris
ENSG00000151576	QTRT2	100	93.793	ENSCAFG00020006930	QTRT2	100	91.807	Canis_lupus_dingo
ENSG00000151576	QTRT2	100	90.602	ENSCHIG00000016908	QTRT2	100	90.602	Capra_hircus
ENSG00000151576	QTRT2	100	93.253	ENSTSYG00000001882	QTRT2	100	93.253	Carlito_syrichta
ENSG00000151576	QTRT2	100	75.172	ENSCAPG00000007379	QTRT2	99	89.655	Cavia_aperea
ENSG00000151576	QTRT2	100	92.414	ENSCPOG00000013988	QTRT2	99	89.130	Cavia_porcellus
ENSG00000151576	QTRT2	100	97.260	ENSCCAG00000025622	QTRT2	100	96.627	Cebus_capucinus
ENSG00000151576	QTRT2	100	97.931	ENSCATG00000035474	QTRT2	100	95.082	Cercocebus_atys
ENSG00000151576	QTRT2	100	92.414	ENSCLAG00000012056	QTRT2	100	88.916	Chinchilla_lanigera
ENSG00000151576	QTRT2	100	94.699	ENSCSAG00000006914	QTRT2	100	94.699	Chlorocebus_sabaeus
ENSG00000151576	QTRT2	100	94.444	ENSCHOG00000004763	QTRT2	99	80.267	Choloepus_hoffmanni
ENSG00000151576	QTRT2	100	84.848	ENSCPBG00000003124	QTRT2	99	70.048	Chrysemys_picta_bellii
ENSG00000151576	QTRT2	93	33.788	ENSCING00000020677	-	100	33.065	Ciona_intestinalis
ENSG00000151576	QTRT2	100	95.904	ENSCANG00000040661	QTRT2	100	95.904	Colobus_angolensis_palliatus
ENSG00000151576	QTRT2	100	91.034	ENSCGRG00001019383	Qtrt2	99	89.362	Cricetulus_griseus_chok1gshd
ENSG00000151576	QTRT2	100	91.034	ENSCGRG00000006970	Qtrt2	99	89.639	Cricetulus_griseus_crigri
ENSG00000151576	QTRT2	100	63.636	ENSCSEG00000017068	qtrt2	97	55.556	Cynoglossus_semilaevis
ENSG00000151576	QTRT2	99	57.416	ENSCVAG00000005581	qtrt2	98	57.518	Cyprinodon_variegatus
ENSG00000151576	QTRT2	100	75.758	ENSDARG00000016093	qtrt2	99	55.238	Danio_rerio
ENSG00000151576	QTRT2	97	89.506	ENSDNOG00000031370	QTRT2	97	90.230	Dasypus_novemcinctus
ENSG00000151576	QTRT2	100	90.345	ENSDORG00000004310	Qtrt2	100	89.362	Dipodomys_ordii
ENSG00000151576	QTRT2	99	30.303	FBgn0036000	CG3434	62	30.303	Drosophila_melanogaster
ENSG00000151576	QTRT2	100	91.892	ENSETEG00000018508	QTRT2	100	75.962	Echinops_telfairi
ENSG00000151576	QTRT2	70	32.414	ENSEBUG00000008093	qtrt2	97	32.414	Eptatretus_burgeri
ENSG00000151576	QTRT2	100	92.048	ENSEASG00005012420	QTRT2	100	92.048	Equus_asinus_asinus
ENSG00000151576	QTRT2	100	91.807	ENSECAG00000002091	QTRT2	98	90.867	Equus_caballus
ENSG00000151576	QTRT2	76	86.441	ENSEEUG00000012169	-	78	88.542	Erinaceus_europaeus
ENSG00000151576	QTRT2	100	60.690	ENSELUG00000013496	qtrt2	98	55.285	Esox_lucius
ENSG00000151576	QTRT2	100	93.012	ENSFCAG00000027207	QTRT2	100	93.012	Felis_catus
ENSG00000151576	QTRT2	92	81.818	ENSFALG00000006002	QTRT2	97	66.667	Ficedula_albicollis
ENSG00000151576	QTRT2	100	86.571	ENSFDAG00000015038	QTRT2	97	88.010	Fukomys_damarensis
ENSG00000151576	QTRT2	99	56.938	ENSFHEG00000017445	qtrt2	98	57.041	Fundulus_heteroclitus
ENSG00000151576	QTRT2	98	54.034	ENSGMOG00000015771	qtrt2	99	54.034	Gadus_morhua
ENSG00000151576	QTRT2	100	84.848	ENSGALG00000037485	QTRT2	97	63.942	Gallus_gallus
ENSG00000151576	QTRT2	98	56.699	ENSGAFG00000007550	qtrt2	97	56.802	Gambusia_affinis
ENSG00000151576	QTRT2	99	56.174	ENSGACG00000003260	qtrt2	98	56.174	Gasterosteus_aculeatus
ENSG00000151576	QTRT2	100	84.848	ENSGAGG00000010771	QTRT2	100	69.322	Gopherus_agassizii
ENSG00000151576	QTRT2	100	99.353	ENSGGOG00000011830	QTRT2	100	99.353	Gorilla_gorilla
ENSG00000151576	QTRT2	100	55.263	ENSHBUG00000017045	qtrt2	96	56.295	Haplochromis_burtoni
ENSG00000151576	QTRT2	98	78.378	ENSHGLG00000002410	-	98	78.378	Heterocephalus_glaber_female
ENSG00000151576	QTRT2	100	93.103	ENSHGLG00000010705	-	99	89.787	Heterocephalus_glaber_female
ENSG00000151576	QTRT2	98	78.378	ENSHGLG00100004326	-	98	78.378	Heterocephalus_glaber_male
ENSG00000151576	QTRT2	100	93.103	ENSHGLG00100003163	-	99	89.787	Heterocephalus_glaber_male
ENSG00000151576	QTRT2	99	53.222	ENSHCOG00000018359	qtrt2	97	53.222	Hippocampus_comes
ENSG00000151576	QTRT2	99	55.048	ENSIPUG00000010893	qtrt2	92	55.048	Ictalurus_punctatus
ENSG00000151576	QTRT2	100	92.414	ENSSTOG00000000303	QTRT2	99	90.171	Ictidomys_tridecemlineatus
ENSG00000151576	QTRT2	92	86.275	ENSJJAG00000000107	Qtrt2	89	86.339	Jaculus_jaculus
ENSG00000151576	QTRT2	100	63.889	ENSKMAG00000009788	qtrt2	97	56.068	Kryptolebias_marmoratus
ENSG00000151576	QTRT2	99	56.522	ENSLBEG00000018687	qtrt2	98	56.770	Labrus_bergylta
ENSG00000151576	QTRT2	99	83.333	ENSLACG00000008339	QTRT2	99	64.583	Latimeria_chalumnae
ENSG00000151576	QTRT2	100	72.727	ENSLOCG00000003146	qtrt2	96	57.385	Lepisosteus_oculatus
ENSG00000151576	QTRT2	100	93.103	ENSLAFG00000005036	QTRT2	100	90.129	Loxodonta_africana
ENSG00000151576	QTRT2	100	94.940	ENSMFAG00000039762	QTRT2	100	94.614	Macaca_fascicularis
ENSG00000151576	QTRT2	100	95.210	ENSMMUG00000001953	QTRT2	100	95.210	Macaca_mulatta
ENSG00000151576	QTRT2	100	94.940	ENSMNEG00000029857	QTRT2	100	94.940	Macaca_nemestrina
ENSG00000151576	QTRT2	100	95.181	ENSMLEG00000034589	QTRT2	100	95.082	Mandrillus_leucophaeus
ENSG00000151576	QTRT2	98	57.869	ENSMAMG00000001620	qtrt2	96	57.971	Mastacembelus_armatus
ENSG00000151576	QTRT2	99	55.476	ENSMZEG00005021955	qtrt2	96	55.582	Maylandia_zebra
ENSG00000151576	QTRT2	99	65.753	ENSMGAG00000014322	QTRT2	97	66.092	Meleagris_gallopavo
ENSG00000151576	QTRT2	100	89.041	ENSMAUG00000013256	Qtrt2	100	88.936	Mesocricetus_auratus
ENSG00000151576	QTRT2	100	94.444	ENSMICG00000049101	QTRT2	99	92.978	Microcebus_murinus
ENSG00000151576	QTRT2	100	90.345	ENSMOCG00000020315	Qtrt2	100	89.362	Microtus_ochrogaster
ENSG00000151576	QTRT2	97	71.429	ENSMMOG00000002808	qtrt2	100	55.224	Mola_mola
ENSG00000151576	QTRT2	100	77.778	ENSMODG00000018172	QTRT2	99	76.570	Monodelphis_domestica
ENSG00000151576	QTRT2	100	66.667	ENSMALG00000021589	qtrt2	87	56.145	Monopterus_albus
ENSG00000151576	QTRT2	100	94.444	MGP_CAROLIEiJ_G0020758	Qtrt2	99	88.412	Mus_caroli
ENSG00000151576	QTRT2	100	88.276	ENSMUSG00000022704	Qtrt2	99	89.270	Mus_musculus
ENSG00000151576	QTRT2	100	90.411	MGP_PahariEiJ_G0016458	Qtrt2	99	89.787	Mus_pahari
ENSG00000151576	QTRT2	99	89.655	MGP_SPRETEiJ_G0021657	Qtrt2	99	89.270	Mus_spretus
ENSG00000151576	QTRT2	100	92.123	ENSMPUG00000000279	QTRT2	100	91.566	Mustela_putorius_furo
ENSG00000151576	QTRT2	100	91.667	ENSMLUG00000004733	QTRT2	100	91.325	Myotis_lucifugus
ENSG00000151576	QTRT2	100	94.444	ENSNGAG00000023502	Qtrt2	100	87.711	Nannospalax_galili
ENSG00000151576	QTRT2	98	56.794	ENSNBRG00000022845	qtrt2	90	55.647	Neolamprologus_brichardi
ENSG00000151576	QTRT2	100	98.382	ENSNLEG00000035353	QTRT2	97	98.382	Nomascus_leucogenys
ENSG00000151576	QTRT2	100	64.726	ENSMEUG00000004034	QTRT2	100	67.816	Notamacropus_eugenii
ENSG00000151576	QTRT2	100	86.111	ENSOPRG00000014419	QTRT2	99	73.430	Ochotona_princeps
ENSG00000151576	QTRT2	100	93.793	ENSODEG00000005189	-	100	88.916	Octodon_degus
ENSG00000151576	QTRT2	100	86.265	ENSODEG00000001407	-	100	86.265	Octodon_degus
ENSG00000151576	QTRT2	99	56.115	ENSONIG00000014074	qtrt2	99	56.115	Oreochromis_niloticus
ENSG00000151576	QTRT2	100	72.093	ENSOANG00000002883	QTRT2	89	69.639	Ornithorhynchus_anatinus
ENSG00000151576	QTRT2	99	89.130	ENSOCUG00000002603	QTRT2	99	89.130	Oryctolagus_cuniculus
ENSG00000151576	QTRT2	97	82.143	ENSORLG00000009211	qtrt2	99	56.039	Oryzias_latipes
ENSG00000151576	QTRT2	97	82.143	ENSORLG00020013554	qtrt2	99	55.875	Oryzias_latipes_hni
ENSG00000151576	QTRT2	97	82.143	ENSORLG00015013318	qtrt2	97	55.635	Oryzias_latipes_hsok
ENSG00000151576	QTRT2	97	82.143	ENSOMEG00000006725	qtrt2	98	55.718	Oryzias_melastigma
ENSG00000151576	QTRT2	100	94.521	ENSOGAG00000015070	QTRT2	100	93.976	Otolemur_garnettii
ENSG00000151576	QTRT2	100	91.325	ENSOARG00000019572	QTRT2	100	91.038	Ovis_aries
ENSG00000151576	QTRT2	100	99.658	ENSPPAG00000039629	QTRT2	100	99.532	Pan_paniscus
ENSG00000151576	QTRT2	100	93.012	ENSPPRG00000002158	QTRT2	100	93.012	Panthera_pardus
ENSG00000151576	QTRT2	100	93.012	ENSPTIG00000009811	QTRT2	100	93.012	Panthera_tigris_altaica
ENSG00000151576	QTRT2	100	99.676	ENSPTRG00000015240	QTRT2	100	99.676	Pan_troglodytes
ENSG00000151576	QTRT2	100	95.181	ENSPANG00000006514	QTRT2	100	95.181	Papio_anubis
ENSG00000151576	QTRT2	100	75.758	ENSPKIG00000013085	qtrt2	98	54.545	Paramormyrops_kingsleyae
ENSG00000151576	QTRT2	99	90.909	ENSPSIG00000002503	QTRT2	96	70.531	Pelodiscus_sinensis
ENSG00000151576	QTRT2	98	56.014	ENSPMGG00000023703	qtrt2	97	54.567	Periophthalmus_magnuspinnatus
ENSG00000151576	QTRT2	100	91.667	ENSPEMG00000008488	Qtrt2	100	87.952	Peromyscus_maniculatus_bairdii
ENSG00000151576	QTRT2	100	77.778	ENSPCIG00000019843	QTRT2	100	76.145	Phascolarctos_cinereus
ENSG00000151576	QTRT2	97	75.000	ENSPFOG00000009940	qtrt2	99	55.769	Poecilia_formosa
ENSG00000151576	QTRT2	97	78.571	ENSPLAG00000002496	qtrt2	98	55.687	Poecilia_latipinna
ENSG00000151576	QTRT2	97	75.000	ENSPMEG00000016642	qtrt2	98	56.039	Poecilia_mexicana
ENSG00000151576	QTRT2	99	55.932	ENSPREG00000018812	qtrt2	98	56.039	Poecilia_reticulata
ENSG00000151576	QTRT2	100	99.036	ENSPPYG00000013531	QTRT2	100	98.829	Pongo_abelii
ENSG00000151576	QTRT2	67	95.455	ENSPCAG00000010229	-	80	95.455	Procavia_capensis
ENSG00000151576	QTRT2	99	94.502	ENSPCOG00000020933	QTRT2	99	94.313	Propithecus_coquereli
ENSG00000151576	QTRT2	100	92.771	ENSPVAG00000008515	QTRT2	100	92.771	Pteropus_vampyrus
ENSG00000151576	QTRT2	89	57.333	ENSPNYG00000004318	qtrt2	71	55.676	Pundamilia_nyererei
ENSG00000151576	QTRT2	100	69.697	ENSPNAG00000020484	qtrt2	95	56.658	Pygocentrus_nattereri
ENSG00000151576	QTRT2	100	89.041	ENSRNOG00000060729	Qtrt2	100	87.952	Rattus_norvegicus
ENSG00000151576	QTRT2	100	94.458	ENSRBIG00000039154	QTRT2	100	94.145	Rhinopithecus_bieti
ENSG00000151576	QTRT2	100	94.940	ENSRROG00000034546	QTRT2	100	94.940	Rhinopithecus_roxellana
ENSG00000151576	QTRT2	100	96.575	ENSSBOG00000024610	QTRT2	100	95.904	Saimiri_boliviensis_boliviensis
ENSG00000151576	QTRT2	100	77.778	ENSSHAG00000006503	QTRT2	99	75.481	Sarcophilus_harrisii
ENSG00000151576	QTRT2	100	78.571	ENSSFOG00015016750	qtrt2	99	49.043	Scleropages_formosus
ENSG00000151576	QTRT2	99	59.247	ENSSMAG00000014011	qtrt2	99	58.173	Scophthalmus_maximus
ENSG00000151576	QTRT2	98	58.419	ENSSDUG00000015365	qtrt2	96	57.452	Seriola_dumerili
ENSG00000151576	QTRT2	98	59.233	ENSSLDG00000003543	qtrt2	96	58.010	Seriola_lalandi_dorsalis
ENSG00000151576	QTRT2	99	71.134	ENSSPUG00000002159	QTRT2	99	59.903	Sphenodon_punctatus
ENSG00000151576	QTRT2	100	59.247	ENSSPAG00000015433	qtrt2	98	57.692	Stegastes_partitus
ENSG00000151576	QTRT2	100	94.217	ENSSSCG00000011912	QTRT2	100	94.217	Sus_scrofa
ENSG00000151576	QTRT2	96	81.818	ENSTGUG00000013406	QTRT2	97	65.686	Taeniopygia_guttata
ENSG00000151576	QTRT2	97	85.714	ENSTRUG00000000756	qtrt2	99	59.314	Takifugu_rubripes
ENSG00000151576	QTRT2	100	56.522	ENSTNIG00000012725	qtrt2	96	57.074	Tetraodon_nigroviridis
ENSG00000151576	QTRT2	92	92.157	ENSTBEG00000003357	QTRT2	83	91.758	Tupaia_belangeri
ENSG00000151576	QTRT2	100	89.041	ENSTTRG00000000180	QTRT2	100	89.943	Tursiops_truncatus
ENSG00000151576	QTRT2	100	93.103	ENSUAMG00000018473	QTRT2	100	91.489	Ursus_americanus
ENSG00000151576	QTRT2	92	92.157	ENSVPAG00000011963	QTRT2	84	93.373	Vicugna_pacos
ENSG00000151576	QTRT2	100	94.483	ENSVVUG00000022159	QTRT2	100	92.340	Vulpes_vulpes
ENSG00000151576	QTRT2	100	65.854	ENSXETG00000002805	qtrt2	100	63.025	Xenopus_tropicalis
ENSG00000151576	QTRT2	97	78.571	ENSXCOG00000009508	qtrt2	96	55.952	Xiphophorus_couchianus
ENSG00000151576	QTRT2	97	78.571	ENSXMAG00000010094	qtrt2	97	56.280	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005737	cytoplasm	-	ISS	Component
GO:0005739	mitochondrion	-	ISS	Component
GO:0005741	mitochondrial outer membrane	-	TAS	Component
GO:0006400	tRNA modification	-	TAS	Process
GO:0008479	queuine tRNA-ribosyltransferase activity	20354154.	IC	Function
GO:0032991	protein-containing complex	20354154.	IPI	Component
GO:0042803	protein homodimerization activity	20354154.	IDA	Function
GO:0046872	metal ion binding	-	IEA	Function
GO:0046982	protein heterodimerization activity	20354154.	IDA	Function
GO:0101030	tRNA-guanine transglycosylation	20354154.	IDA	Process