EuRBPDB

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  • Description
  • RBDs
  • RBPome
  • PRI
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • PPI
  • Paralogs
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000151923 (Gene tree)
Gene ID
7073
Gene Symbol
TIAL1
Alias
TIAR
Full Name
TIA1 cytotoxic granule associated RNA binding protein like 1
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Minus strand
Length
25,228 bases
Position
chr10:119,571,802-119,597,029
Accession
11804
RBP type
canonical RBP
Summary
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008]
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000394902RRM_1PF00076.224.6e-6313
ENSP00000394902RRM_1PF00076.224.6e-6323
ENSP00000394902RRM_1PF00076.224.6e-6333
ENSP00000358089RRM_1PF00076.226.7e-6013
ENSP00000358089RRM_1PF00076.226.7e-6023
ENSP00000358089RRM_1PF00076.226.7e-6033
ENSP00000403573RRM_1PF00076.224e-3312
ENSP00000403573RRM_1PF00076.224e-3322
ENSP00000358082RRM_1PF00076.226.9e-1612
ENSP00000358082RRM_1PF00076.226.9e-1622
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNANascentRICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8
Protein-RNA interaction(RNA-Binding Site)
Click here to download all RNA binding sites

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
16091628Novel DNA-binding properties of the RNA-binding protein TIAR.Nucleic Acids Res2005 Aug 9Suswam EA-
25108040Pathological stress granules in Alzheimer's disease.Brain Res2014 Oct 10Ash PEdoi: 10.1016/j.brainres.2014.05.052
8871565Structure, tissue distribution and genomic organization of the murine RRM-type RNA binding proteins TIA-1 and TIAR.Nucleic Acids Res1996 Oct 1Beck AR-
8576255Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities.J Biol Chem1996 Feb 2Dember LM-
16527256Identification of FUSE-binding proteins as interacting partners of TIA proteins.Biochem Biophys Res Commun2006 Apr 28Rothe F-
12414941Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replication.J Virol2002 DecLi W-
10613902RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules.J Cell Biol1999 Dec 27Kedersha NL-
16278295Identification of the sequence determinants mediating the nucleo-cytoplasmic shuttling of TIAR and TIA-1 RNA-binding proteins.J Cell Sci2005 Dec 1Zhang T-
14662769Identification of RNA-binding proteins in RAW 264.7 cells that recognize a lipopolysaccharide-responsive element in the 3-untranslated region of the murine cyclooxygenase-2 mRNA.J Biol Chem2004 Feb 27Cok SJ-
18490444MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90.Mol Cell Biol2008 JulKuwano Ydoi: 10.1128/MCB.00165-08
17488725Two isoforms of the T-cell intracellular antigen 1 (TIA-1) splicing factor display distinct splicing regulation activities. Control of TIA-1 isoform ratio by TIA-1-related protein.J Biol Chem2007 Jul 6Izquierdo JM-
20596534Impaired embryonic development in mice overexpressing the RNA-binding protein TIAR.PLoS One2010 Jun 28Kharraz Ydoi: 10.1371/journal.pone.0011352.
20477871The splicing factor ASF/SF2 is associated with TIA-1-related/TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression.FEBS J2010 JunDelestienne Ndoi: 10.1111/j.1742-4658.2010.07664.x
26981431Genome-wide analysis of TIAR RNA ligands in mouse macrophages before and after LPS stimulation.Genom Data2016 Feb 8Kharraz Ydoi: 10.1016/j.gdata.2016.02.007
30578631Activation of integrated stress response pathway regulates IL-1β production through posttranscriptional and translational reprogramming in macrophages.Eur J Immunol2019 FebNaz Sdoi: 10.1002/eji.201847513
15525674Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes.Mol Biol Cell2005 JanThomas MG-
18005751Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase.Cell Host Microbe2007 Nov 15White JP-
21233170Different modes of interaction by TIAR and HuR with target RNA and DNA.Nucleic Acids Res2011 FebKim HSdoi: 10.1093/nar/gkq837
23603827Distinct binding properties of TIAR RRMs and linker region.RNA Biol2013 AprKim HSdoi: 10.4161/rna.24341
30327138Transcriptome meta-analysis identifies immune signature comprising of RNA binding proteins in ulcerative colitis patients.Cell Immunol2018 DecNaz Sdoi: 10.1016/j.cellimm.2018.09.003
7533298The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death.Proc Natl Acad Sci U S A1995 Feb 28Taupin JL-
1326761Identification and functional characterization of a TIA-1-related nucleolysin.Proc Natl Acad Sci U S A1992 Sep 15Kawakami A-
16600875Posttranscriptional derepression of GADD45alpha by genotoxic stress.Mol Cell2006 Apr 7Lal A-
12533540TIA-1 or TIAR is required for DT40 cell viability.J Biol Chem2003 Mar 21Le Guiner C-
12440953AU-rich element-mediated translational control: complexity and multiple activities of trans-activating factors.Biochem Soc Trans2002 NovZhang T-
12440955Stress granules: sites of mRNA triage that regulate mRNA stability and translatability.Biochem Soc Trans2002 NovKedersha N-
12380690Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation.Cell Stress Chaperones2002 AprAnderson P-
12140254Stressful initiations.J Cell Sci2002 Aug 15Anderson P-
11809833Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules.Mol Biol Cell2002 JanKedersha N-
10640826Localization of the rat genes encoding the RNA binding protein TIAR (Tial1) and the integrin beta1 subunit (Itgb1): evidence for multiple homology relationships between the rat chromosome 19q12 region and the human genome.Cytogenet Cell Genet1999Szpirer C-
16890199Control of the ATP synthase beta subunit expression by RNA-binding proteins TIA-1, TIAR, and HuR.Biochem Biophys Res Commun2006 Sep 22Izquierdo JM-
16221671Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules.J Biol Chem2005 Dec 30Baez MV-
15964806Global analysis of Pub1p targets reveals a coordinate control of gene expression through modulation of binding and stability.Mol Cell Biol2005 JulDuttagupta R-
15514971IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR.Int J Cancer2005 Mar 1Suswam EA-
23077311Induction of stress granule-like structures in vesicular stomatitis virus-infected cells.J Virol2013 JanDinh PXdoi: 10.1128/JVI.02305-12
19861488Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3.Reproduction2010 FebYamaji Mdoi: 10.1530/REP-09-0373
19819975Characterization of conserved tandem donor sites and intronic motifs required for alternative splicing in corticosteroid receptor genes.Endocrinology2009 NovRivers Cdoi: 10.1210/en.2009-0346
18456862A systematic analysis of intronic sequences downstream of 5' splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation.Genome Res2008 AugAznarez Idoi: 10.1101/gr.073155.107
17682065Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR.Mol Cell Biol2007 OctKim HS-
17466948The RNA-binding protein PTB exerts translational control on 3'-untranslated region of the mRNA for the ATP synthase beta-subunit.Biochem Biophys Res Commun2007 Jun 15Reyes R-
20435889MicroRNAs distinguish translational from transcriptional silencing during endotoxin tolerance.J Biol Chem2010 Jul 2El Gazzar Mdoi: 10.1074/jbc.M110.115063
25352557HIV-2 genomic RNA accumulates in stress granules in the absence of active translation.Nucleic Acids Res2014 Nov 10Soto-Rifo Rdoi: 10.1093/nar/gku1017
24696465The stress granule component TIA-1 binds tick-borne encephalitis virus RNA and is recruited to perinuclear sites of viral replication to inhibit viral translation.J Virol2014 JunAlbornoz Adoi: 10.1128/JVI.03736-13
24627160Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.J Mol Cell Biol2014 JunMiloslavski Rdoi: 10.1093/jmcb/mju008
24566137HuR and TIA1/TIAL1 are involved in regulation of alternative splicing of SIRT1 pre-mRNA.Int J Mol Sci2014 Feb 20Zhao Wdoi: 10.3390/ijms15022946.
23913578The C. elegans TIA-1/TIAR homolog TIAR-1 is required to induce germ cell apoptosis.Genesis2013 OctSilva-Garcia CGdoi: 10.1002/dvg.22418
26865701The Stress Granule RNA-Binding Protein TIAR-1 Protects Female Germ Cells from Heat Shock in Caenorhabditis elegans.G3 (Bethesda)2016 Apr 7Huelgas-Morales Gdoi: 10.1534/g3.115.026815.
25918534Targeted Knockdown of RNA-Binding Protein TIAR for Promoting Self-Renewal and Attenuating Differentiation of Mouse Embryonic Stem Cells.Stem Cells Int2015Geng Zdoi: 10.1155/2015/657325
29621237Amino acid starvation sensing dampens IL-1β production by activating riboclustering and autophagy.PLoS Biol2018 Apr 5Battu Sdoi: 10.1371/journal.pbio.2005317
30533021Transcriptome-wide analysis links the short-term expression of the b isoforms of TIA proteins to protective proteostasis-mediated cell quiescence response.PLoS One2018 Dec 11Carrascoso Idoi: 10.1371/journal.pone.0208526
30569136miR2233p/TIAL1 interaction is involved in the mechanisms associated with the neuroprotective effects of dexmedetomidine on hippocampal neuronal cells invitro.Mol Med Rep2019 FebWang Qdoi: 10.3892/mmr.2018.9742
30977984Post-Transcriptional Modulation of aENaC mRNA in Alveolar Epithelial Cells: Involvement of its 3' Untranslated Region.Cell Physiol Biochem2019Migneault Fdoi: 10.33594/000000068.
22855484Hepatitis C virus (HCV) induces formation of stress granules whose proteins regulate HCV RNA replication and virus assembly and egress.J Virol2012 OctGaraigorta U-
20412850Thy-1 mRNA destabilization by norepinephrine a 3' UTR cAMP responsive decay element and involves RNA binding proteins.Brain Behav Immun2010 OctLaJevic MDdoi: 10.1016/j.bbi.2010.04.006
19805546Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR): implications for impaired post-transcriptional regulation of vascular endothelial growth factor.J Biol Chem2009 Dec 4Lu Ldoi: 10.1074/jbc.M109.067918
24590458The involvement of mRNA processing factors TIA-1, TIAR, and PABP-1 during mammalian hibernation.Cell Stress Chaperones2014 NovTessier SNdoi: 10.1007/s12192-014-0505-8
28298474Tumor protein D52 expression is post-transcriptionally regulated by T-cell intercellular antigen (TIA) 1 and TIA-related protein via mRNA stability.Biochem J2017 May 4Motohashi Hdoi: 10.1042/BCJ20160942.
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000495821TIAL1-212372--- (aa)--
ENST00000489822TIAL1-2112222NR_136662-- (aa)--
ENST00000463089TIAL1-207907--- (aa)--
ENST00000462373TIAL1-206260--- (aa)--
ENST00000470635TIAL1-208336--- (aa)--
ENST00000412524TIAL1-204515-ENSP00000403573132 (aa)-E7ETJ9
ENST00000436547TIAL1-2051401-ENSP00000394902375 (aa)-Q01085
ENST00000497671TIAL1-2132321-ENSP00000431009135 (aa)-E7ETC0
ENST00000369087TIAL1-2021566--- (aa)--
ENST00000369086TIAL1-201490-ENSP0000035808285 (aa)-A6NKZ9
ENST00000369093TIAL1-2035072XM_024448151ENSP00000358089392 (aa)XP_024303919Q01085
ENST00000479729TIAL1-210485-ENSP0000048082528 (aa)-A0A087WX93
ENST00000470781TIAL1-2091727NR_136663-- (aa)--
Gene Model
Click here to download ENSG00000151923's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000151923Antineoplastic Agents7E-727047539
ENSG00000151923Cell Survival7E-727047539
ENSG00000151923Ovarian Neoplasms7E-727047539
ENSG00000151923Paclitaxel7E-727047539
ENSG00000151923Parkinson Disease3E-1127182965
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000151923's network

* RBP PPI network refers to all genes directly bind to RBP
Paralogs
Ensembl IDGene SymbolCoverageIdentiy ParalogGene SymbolCoverageIdentiy
ENSG00000151923TIAL16431.461ENSG00000147274RBMX8332.308
ENSG00000151923TIAL19031.481ENSG00000048740CELF26134.177
ENSG00000151923TIAL19234.375ENSG00000180098TRNAU1AP6032.386
ENSG00000151923TIAL19138.028ENSG00000179950PUF606530.726
ENSG00000151923TIAL16232.927ENSG00000131051RBM395032.927
ENSG00000151923TIAL19836.620ENSG00000090621PABPC49934.783
ENSG00000151923TIAL16634.444ENSG00000242389RBMY1E7936.923
ENSG00000151923TIAL15541.096ENSG00000102317RBM35337.349
ENSG00000151923TIAL16634.444ENSG00000242875RBMY1B7936.923
ENSG00000151923TIAL19834.783ENSG00000174740PABPC59233.803
ENSG00000151923TIAL16634.444ENSG00000234414RBMY1A17936.923
ENSG00000151923TIAL19236.986ENSG00000196361ELAVL39037.179
ENSG00000151923TIAL19837.692ENSG00000151846PABPC35637.692
ENSG00000151923TIAL19136.620ENSG00000162374ELAVL48835.897
ENSG00000151923TIAL16435.227ENSG00000076053RBM77034.286
ENSG00000151923TIAL18632.812ENSG00000153250RBMS15331.343
ENSG00000151923TIAL15534.247ENSG00000265241RBM8A9131.959
ENSG00000151923TIAL17337.333ENSG00000159409CELF36934.091
ENSG00000151923TIAL19033.613ENSG00000115053NCL9030.952
ENSG00000151923TIAL18430.973ENSG00000173933RBM49431.034
ENSG00000151923TIAL16634.444ENSG00000244395RBMY1D7936.923
ENSG00000151923TIAL19630.769ENSG00000151962RBM465230.714
ENSG00000151923TIAL19134.167ENSG00000186288PABPC1L2A7933.333
ENSG00000151923TIAL18430.088ENSG00000173914RBM4B9130.345
ENSG00000151923TIAL19237.500ENSG00000143368SF3B47136.719
ENSG00000151923TIAL15040.909ENSG00000132819RBM385440.909
ENSG00000151923TIAL16432.584ENSG00000213516RBMXL16532.258
ENSG00000151923TIAL19232.432ENSG00000066044ELAVL19330.769
ENSG00000151923TIAL19135.211ENSG00000107105ELAVL29334.615
ENSG00000151923TIAL15432.394ENSG00000161547SRSF25532.877
ENSG00000151923TIAL19639.437ENSG00000101104PABPC1L7539.437
ENSG00000151923TIAL15436.000ENSG00000188120DAZ17030.392
ENSG00000151923TIAL19134.167ENSG00000184388PABPC1L2B7933.333
ENSG00000151923TIAL19844.828ENSG00000070756PABPC19936.538
ENSG00000151923TIAL16838.824ENSG00000099622CIRBP9940.506
ENSG00000151923TIAL16832.222ENSG00000114503NCBP26637.333
ENSG00000151923TIAL110089.394ENSG00000116001TIA19090.511
ENSG00000151923TIAL17130.928ENSG00000140488CELF65334.177
ENSG00000151923TIAL19833.613ENSG00000254535PABPC4L9533.613
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000151923TIAL19899.219ENSAMEG00000010147TIAL19899.219Ailuropoda_melanoleuca
ENSG00000151923TIAL19997.710ENSAPLG00000009088TIAL19797.113Anas_platyrhynchos
ENSG00000151923TIAL19997.710ENSACAG00000016986TIAL19195.845Anolis_carolinensis
ENSG00000151923TIAL1100100.000ENSANAG00000034445TIAL1100100.000Aotus_nancymaae
ENSG00000151923TIAL1100100.000ENSBTAG00000004080TIAL1100100.000Bos_taurus
ENSG00000151923TIAL1100100.000ENSCJAG00000019682TIAL1100100.000Callithrix_jacchus
ENSG00000151923TIAL1100100.000ENSCAFG00000012171TIAL1100100.000Canis_familiaris
ENSG00000151923TIAL1100100.000ENSCAFG00020013891TIAL1100100.000Canis_lupus_dingo
ENSG00000151923TIAL1100100.000ENSCHIG00000020810TIAL1100100.000Capra_hircus
ENSG00000151923TIAL1100100.000ENSTSYG00000004348TIAL1100100.000Carlito_syrichta
ENSG00000151923TIAL19996.429ENSCCAG00000002561TIAL194100.000Cebus_capucinus
ENSG00000151923TIAL19996.429ENSCCAG00000027590-10094.118Cebus_capucinus
ENSG00000151923TIAL1100100.000ENSCATG00000043838TIAL1100100.000Cercocebus_atys
ENSG00000151923TIAL110099.745ENSCLAG00000001273TIAL110099.745Chinchilla_lanigera
ENSG00000151923TIAL1100100.000ENSCSAG00000004734TIAL1100100.000Chlorocebus_sabaeus
ENSG00000151923TIAL19879.528ENSCHOG00000009888TIAL110079.528Choloepus_hoffmanni
ENSG00000151923TIAL19997.710ENSCPBG00000001103TIAL110096.931Chrysemys_picta_bellii
ENSG00000151923TIAL1100100.000ENSCANG00000017395TIAL1100100.000Colobus_angolensis_palliatus
ENSG00000151923TIAL1100100.000ENSCGRG00001012762Tial110099.200Cricetulus_griseus_chok1gshd
ENSG00000151923TIAL19997.710ENSCGRG00000017323Tial110099.213Cricetulus_griseus_crigri
ENSG00000151923TIAL197100.000ENSDNOG00000009552TIAL1100100.000Dasypus_novemcinctus
ENSG00000151923TIAL1100100.000ENSDORG00000010683Tial1100100.000Dipodomys_ordii
ENSG00000151923TIAL19798.950ENSETEG00000020276TIAL110098.950Echinops_telfairi
ENSG00000151923TIAL1100100.000ENSEASG00005014449TIAL1100100.000Equus_asinus_asinus
ENSG00000151923TIAL1100100.000ENSECAG00000009970TIAL1100100.000Equus_caballus
ENSG00000151923TIAL19997.710ENSEEUG00000011861TIAL110098.688Erinaceus_europaeus
ENSG00000151923TIAL1100100.000ENSFCAG00000031690TIAL1100100.000Felis_catus
ENSG00000151923TIAL1100100.000ENSFDAG00000003933TIAL110099.733Fukomys_damarensis
ENSG00000151923TIAL1100100.000ENSGALG00000009427TIAL110097.059Gallus_gallus
ENSG00000151923TIAL19997.710ENSGAGG00000023119TIAL110097.187Gopherus_agassizii
ENSG00000151923TIAL1100100.000ENSGGOG00000001816TIAL1100100.000Gorilla_gorilla
ENSG00000151923TIAL19776.781ENSHGLG00000009491-9574.934Heterocephalus_glaber_female
ENSG00000151923TIAL19997.710ENSHGLG00000013775-10091.327Heterocephalus_glaber_female
ENSG00000151923TIAL1100100.000ENSHGLG00100015062TIAL110099.467Heterocephalus_glaber_male
ENSG00000151923TIAL19776.517ENSHGLG00100006330-9574.670Heterocephalus_glaber_male
ENSG00000151923TIAL1100100.000ENSSTOG00000025095TIAL1100100.000Ictidomys_tridecemlineatus
ENSG00000151923TIAL19997.710ENSJJAG00000005398-10099.475Jaculus_jaculus
ENSG00000151923TIAL18785.246ENSJJAG00000022559-10085.246Jaculus_jaculus
ENSG00000151923TIAL19698.780ENSLACG00000011749TIAL19987.724Latimeria_chalumnae
ENSG00000151923TIAL197100.000ENSLAFG00000003412TIAL1100100.000Loxodonta_africana
ENSG00000151923TIAL1100100.000ENSMFAG00000002789TIAL1100100.000Macaca_fascicularis
ENSG00000151923TIAL1100100.000ENSMMUG00000001472TIAL1100100.000Macaca_mulatta
ENSG00000151923TIAL1100100.000ENSMNEG00000032245TIAL1100100.000Macaca_nemestrina
ENSG00000151923TIAL1100100.000ENSMLEG00000034719TIAL1100100.000Mandrillus_leucophaeus
ENSG00000151923TIAL19897.674ENSMGAG00000011368TIAL110092.857Meleagris_gallopavo
ENSG00000151923TIAL169100.000ENSMAUG00000008932-70100.000Mesocricetus_auratus
ENSG00000151923TIAL1100100.000ENSMICG00000037857TIAL1100100.000Microcebus_murinus
ENSG00000151923TIAL1100100.000ENSMOCG00000014244Tial110099.200Microtus_ochrogaster
ENSG00000151923TIAL19997.710ENSMODG00000008865TIAL19997.187Monodelphis_domestica
ENSG00000151923TIAL19998.462ENSMALG00000007782TIAL110076.261Monopterus_albus
ENSG00000151923TIAL1100100.000MGP_CAROLIEiJ_G0030548Tial1100100.000Mus_caroli
ENSG00000151923TIAL1100100.000ENSMUSG00000030846Tial1100100.000Mus_musculus
ENSG00000151923TIAL1100100.000MGP_PahariEiJ_G0013755Tial1100100.000Mus_pahari
ENSG00000151923TIAL1100100.000MGP_SPRETEiJ_G0031662Tial1100100.000Mus_spretus
ENSG00000151923TIAL1100100.000ENSMPUG00000003060TIAL1100100.000Mustela_putorius_furo
ENSG00000151923TIAL1100100.000ENSMLUG00000004645TIAL19998.922Myotis_lucifugus
ENSG00000151923TIAL1100100.000ENSNGAG00000020427Tial110099.733Nannospalax_galili
ENSG00000151923TIAL197100.000ENSNLEG00000016743TIAL1100100.000Nomascus_leucogenys
ENSG00000151923TIAL19997.710ENSMEUG00000013120TIAL19978.517Notamacropus_eugenii
ENSG00000151923TIAL19999.744ENSODEG00000017741TIAL19999.744Octodon_degus
ENSG00000151923TIAL19997.710ENSOANG00000004896-9896.011Ornithorhynchus_anatinus
ENSG00000151923TIAL1100100.000ENSOCUG00000003783TIAL110097.594Oryctolagus_cuniculus
ENSG00000151923TIAL19293.617ENSOMEG00000016815TIAL19874.319Oryzias_melastigma
ENSG00000151923TIAL1100100.000ENSOGAG00000011417TIAL1100100.000Otolemur_garnettii
ENSG00000151923TIAL1100100.000ENSOARG00000002680TIAL1100100.000Ovis_aries
ENSG00000151923TIAL1100100.000ENSPPAG00000043098TIAL1100100.000Pan_paniscus
ENSG00000151923TIAL1100100.000ENSPPRG00000003226TIAL1100100.000Panthera_pardus
ENSG00000151923TIAL1100100.000ENSPTIG00000007899TIAL1100100.000Panthera_tigris_altaica
ENSG00000151923TIAL1100100.000ENSPTRG00000002996TIAL1100100.000Pan_troglodytes
ENSG00000151923TIAL1100100.000ENSPANG00000020518TIAL1100100.000Papio_anubis
ENSG00000151923TIAL1100100.000ENSPEMG00000014538Tial110099.235Peromyscus_maniculatus_bairdii
ENSG00000151923TIAL1100100.000ENSPCIG00000003120TIAL1100100.000Phascolarctos_cinereus
ENSG00000151923TIAL110099.745ENSPPYG00000002703TIAL110099.745Pongo_abelii
ENSG00000151923TIAL110099.491ENSPCAG00000003192TIAL110099.491Procavia_capensis
ENSG00000151923TIAL1100100.000ENSPCOG00000018990TIAL1100100.000Propithecus_coquereli
ENSG00000151923TIAL110099.745ENSPVAG00000017585TIAL110099.745Pteropus_vampyrus
ENSG00000151923TIAL110099.235ENSRNOG00000020271Tial110099.235Rattus_norvegicus
ENSG00000151923TIAL1100100.000ENSRBIG00000027702TIAL1100100.000Rhinopithecus_bieti
ENSG00000151923TIAL1100100.000ENSRROG00000043377TIAL1100100.000Rhinopithecus_roxellana
ENSG00000151923TIAL1100100.000ENSSBOG00000028408TIAL1100100.000Saimiri_boliviensis_boliviensis
ENSG00000151923TIAL19997.710ENSSHAG00000012508TIAL19896.104Sarcophilus_harrisii
ENSG00000151923TIAL19997.710ENSSARG00000012980TIAL110099.476Sorex_araneus
ENSG00000151923TIAL19997.710ENSSPUG00000002412TIAL110095.918Sphenodon_punctatus
ENSG00000151923TIAL19786.435ENSSSCG00000015620-8987.261Sus_scrofa
ENSG00000151923TIAL1100100.000ENSSSCG00000010685-100100.000Sus_scrofa
ENSG00000151923TIAL19997.710ENSTGUG00000011148TIAL110097.113Taeniopygia_guttata
ENSG00000151923TIAL110084.848ENSTRUG00000020927TIAL19974.805Takifugu_rubripes
ENSG00000151923TIAL19287.013ENSTNIG00000013091TIAL19969.501Tetraodon_nigroviridis
ENSG00000151923TIAL19997.710ENSTTRG00000014574TIAL110091.582Tursiops_truncatus
ENSG00000151923TIAL1100100.000ENSUAMG00000009532TIAL1100100.000Ursus_americanus
ENSG00000151923TIAL1100100.000ENSUMAG00000003207TIAL1100100.000Ursus_maritimus
ENSG00000151923TIAL19297.196ENSVPAG00000001240TIAL19792.033Vicugna_pacos
ENSG00000151923TIAL1100100.000ENSVVUG00000011029TIAL1100100.000Vulpes_vulpes
ENSG00000151923TIAL19996.183ENSXETG00000010234tial19188.491Xenopus_tropicalis
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003677DNA binding-IEAFunction
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0005634nucleus-ISSComponent
GO:0005654nucleoplasm-TASComponent
GO:0005737cytoplasm-ISSComponent
GO:0005764lysosome1326761.TASComponent
GO:0006357regulation of transcription by RNA polymerase II9207209.TASProcess
GO:0006915apoptotic process-IEAProcess
GO:0006952defense response1326761.TASProcess
GO:0007281germ cell development-IEAProcess
GO:0008284positive regulation of cell proliferation-IEAProcess
GO:0008543fibroblast growth factor receptor signaling pathway-TASProcess
GO:0010494cytoplasmic stress granule-ISSComponent
GO:0017091AU-rich element binding-IEAFunction
GO:0017145stem cell division-IEAProcess

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