EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000152147 (Gene tree)
Gene ID: 79833
Gene Symbol: GEMIN6
Alias: FLJ23459
Full Name: gem nuclear organelle associated protein 6
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 33,467 bases
Position: chr2:38,751,534-38,785,000
Accession: 20044
RBP type: canonical RBP
Summary: GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).[supplied by OMIM, Jul 2002]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000281950	Gemin6	PF06372.12	2.8e-86	1	1
ENSP00000387191	Gemin6	PF06372.12	6.5e-18	1	1
ENSP00000386613	Gemin6	PF06372.12	2.8e-17	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000281950	GEMIN6-201	3728	-	ENSP00000281950	167 (aa)	-	Q8WXD5
ENST00000409566	GEMIN6-203	834	-	ENSP00000386613	111 (aa)	-	B8ZZ85
ENST00000409011	GEMIN6-202	1210	-	ENSP00000387191	69 (aa)	-	B9A037

Gene Model

Click here to download ENSG00000152147's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000152147	Leukoaraiosis	6.3892649E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000152147's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000152147	GEMIN6	58	46.835	ENSG00000139343	SNRPF	62	46.835

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000152147	GEMIN6	93	46.795	ENSAPOG00000017375	gemin6	93	46.795	Acanthochromis_polyacanthus
ENSG00000152147	GEMIN6	100	91.018	ENSAMEG00000016004	GEMIN6	100	91.018	Ailuropoda_melanoleuca
ENSG00000152147	GEMIN6	94	43.949	ENSACIG00000009880	gemin6	96	43.949	Amphilophus_citrinellus
ENSG00000152147	GEMIN6	95	45.679	ENSAOCG00000021507	-	90	45.679	Amphiprion_ocellaris
ENSG00000152147	GEMIN6	95	45.679	ENSAPEG00000018793	GEMIN6	90	45.679	Amphiprion_percula
ENSG00000152147	GEMIN6	95	44.654	ENSATEG00000014551	gemin6	87	44.654	Anabas_testudineus
ENSG00000152147	GEMIN6	100	62.275	ENSACAG00000006134	GEMIN6	100	62.275	Anolis_carolinensis
ENSG00000152147	GEMIN6	100	97.605	ENSANAG00000034313	GEMIN6	100	97.605	Aotus_nancymaae
ENSG00000152147	GEMIN6	93	42.675	ENSACLG00000004392	gemin6	90	42.675	Astatotilapia_calliptera
ENSG00000152147	GEMIN6	96	50.000	ENSAMXG00000006993	gemin6	95	50.000	Astyanax_mexicanus
ENSG00000152147	GEMIN6	100	89.222	ENSBTAG00000015521	GEMIN6	100	89.222	Bos_taurus
ENSG00000152147	GEMIN6	100	96.407	ENSCJAG00000015169	GEMIN6	100	96.407	Callithrix_jacchus
ENSG00000152147	GEMIN6	100	91.617	ENSCAFG00000029480	GEMIN6	100	91.617	Canis_familiaris
ENSG00000152147	GEMIN6	100	91.617	ENSCAFG00020022803	GEMIN6	93	91.617	Canis_lupus_dingo
ENSG00000152147	GEMIN6	100	88.024	ENSCHIG00000013155	GEMIN6	100	88.024	Capra_hircus
ENSG00000152147	GEMIN6	100	89.222	ENSTSYG00000026011	-	100	89.222	Carlito_syrichta
ENSG00000152147	GEMIN6	98	73.620	ENSTSYG00000030655	-	100	73.620	Carlito_syrichta
ENSG00000152147	GEMIN6	100	81.437	ENSCAPG00000014776	GEMIN6	94	81.437	Cavia_aperea
ENSG00000152147	GEMIN6	100	81.437	ENSCPOG00000034454	GEMIN6	94	81.437	Cavia_porcellus
ENSG00000152147	GEMIN6	100	97.006	ENSCCAG00000026294	GEMIN6	100	97.006	Cebus_capucinus
ENSG00000152147	GEMIN6	99	98.795	ENSCATG00000030487	GEMIN6	100	98.795	Cercocebus_atys
ENSG00000152147	GEMIN6	100	85.030	ENSCLAG00000005345	GEMIN6	94	85.030	Chinchilla_lanigera
ENSG00000152147	GEMIN6	100	98.802	ENSCSAG00000012310	GEMIN6	100	98.802	Chlorocebus_sabaeus
ENSG00000152147	GEMIN6	98	70.122	ENSCPBG00000018250	GEMIN6	98	70.122	Chrysemys_picta_bellii
ENSG00000152147	GEMIN6	94	38.217	ENSCSAVG00000001244	-	96	38.217	Ciona_savignyi
ENSG00000152147	GEMIN6	100	98.802	ENSCANG00000035207	GEMIN6	100	98.802	Colobus_angolensis_palliatus
ENSG00000152147	GEMIN6	100	89.222	ENSCGRG00001017426	Gemin6	100	89.222	Cricetulus_griseus_chok1gshd
ENSG00000152147	GEMIN6	100	89.222	ENSCGRG00000012675	Gemin6	100	89.222	Cricetulus_griseus_crigri
ENSG00000152147	GEMIN6	94	47.771	ENSCSEG00000021066	gemin6	90	47.771	Cynoglossus_semilaevis
ENSG00000152147	GEMIN6	95	42.138	ENSCVAG00000006772	gemin6	88	42.138	Cyprinodon_variegatus
ENSG00000152147	GEMIN6	72	36.885	ENSDARG00000105394	gemin6	87	36.885	Danio_rerio
ENSG00000152147	GEMIN6	100	90.419	ENSDNOG00000009496	GEMIN6	100	90.419	Dasypus_novemcinctus
ENSG00000152147	GEMIN6	99	80.606	ENSDORG00000023512	Gemin6	95	80.606	Dipodomys_ordii
ENSG00000152147	GEMIN6	100	79.641	ENSETEG00000012627	GEMIN6	100	79.641	Echinops_telfairi
ENSG00000152147	GEMIN6	100	94.012	ENSEASG00005005543	GEMIN6	100	94.012	Equus_asinus_asinus
ENSG00000152147	GEMIN6	100	83.957	ENSECAG00000007191	GEMIN6	100	83.957	Equus_caballus
ENSG00000152147	GEMIN6	100	80.240	ENSEEUG00000004733	GEMIN6	99	80.240	Erinaceus_europaeus
ENSG00000152147	GEMIN6	97	52.761	ENSELUG00000018114	GEMIN6	94	52.761	Esox_lucius
ENSG00000152147	GEMIN6	100	90.419	ENSFCAG00000008101	GEMIN6	100	90.419	Felis_catus
ENSG00000152147	GEMIN6	98	58.282	ENSFALG00000002361	GEMIN6	92	58.282	Ficedula_albicollis
ENSG00000152147	GEMIN6	100	85.030	ENSFDAG00000011157	GEMIN6	99	85.030	Fukomys_damarensis
ENSG00000152147	GEMIN6	94	43.949	ENSFHEG00000023042	gemin6	83	43.949	Fundulus_heteroclitus
ENSG00000152147	GEMIN6	89	40.940	ENSGMOG00000016000	gemin6	99	40.940	Gadus_morhua
ENSG00000152147	GEMIN6	100	59.880	ENSGALG00000013821	GEMIN6	100	59.880	Gallus_gallus
ENSG00000152147	GEMIN6	93	41.401	ENSGAFG00000000474	gemin6	80	41.401	Gambusia_affinis
ENSG00000152147	GEMIN6	96	45.963	ENSGACG00000005286	-	95	45.963	Gasterosteus_aculeatus
ENSG00000152147	GEMIN6	98	68.902	ENSGAGG00000003565	GEMIN6	99	68.902	Gopherus_agassizii
ENSG00000152147	GEMIN6	100	99.401	ENSGGOG00000038177	GEMIN6	100	99.401	Gorilla_gorilla
ENSG00000152147	GEMIN6	93	42.675	ENSHBUG00000015030	gemin6	90	42.675	Haplochromis_burtoni
ENSG00000152147	GEMIN6	100	86.228	ENSHGLG00000018364	GEMIN6	94	86.228	Heterocephalus_glaber_female
ENSG00000152147	GEMIN6	100	86.228	ENSHGLG00100004430	GEMIN6	94	86.228	Heterocephalus_glaber_male
ENSG00000152147	GEMIN6	74	44.231	ENSHCOG00000011472	-	61	34.783	Hippocampus_comes
ENSG00000152147	GEMIN6	96	49.068	ENSIPUG00000011728	gemin6	95	49.068	Ictalurus_punctatus
ENSG00000152147	GEMIN6	100	89.820	ENSSTOG00000004408	-	100	89.820	Ictidomys_tridecemlineatus
ENSG00000152147	GEMIN6	100	91.018	ENSSTOG00000032476	-	100	91.018	Ictidomys_tridecemlineatus
ENSG00000152147	GEMIN6	98	82.209	ENSJJAG00000021310	Gemin6	99	82.209	Jaculus_jaculus
ENSG00000152147	GEMIN6	95	45.283	ENSKMAG00000006850	gemin6	86	45.283	Kryptolebias_marmoratus
ENSG00000152147	GEMIN6	98	46.012	ENSLBEG00000025776	gemin6	90	46.012	Labrus_bergylta
ENSG00000152147	GEMIN6	96	65.217	ENSLACG00000003835	GEMIN6	81	65.217	Latimeria_chalumnae
ENSG00000152147	GEMIN6	97	59.259	ENSLOCG00000015777	gemin6	98	59.259	Lepisosteus_oculatus
ENSG00000152147	GEMIN6	100	85.030	ENSLAFG00000031371	GEMIN6	100	85.030	Loxodonta_africana
ENSG00000152147	GEMIN6	99	98.795	ENSMFAG00000035412	GEMIN6	100	98.795	Macaca_fascicularis
ENSG00000152147	GEMIN6	99	98.193	ENSMNEG00000028599	GEMIN6	100	98.193	Macaca_nemestrina
ENSG00000152147	GEMIN6	99	98.795	ENSMLEG00000038376	GEMIN6	100	98.795	Mandrillus_leucophaeus
ENSG00000152147	GEMIN6	92	49.351	ENSMAMG00000017164	gemin6	91	49.351	Mastacembelus_armatus
ENSG00000152147	GEMIN6	93	42.675	ENSMZEG00005015457	-	90	42.675	Maylandia_zebra
ENSG00000152147	GEMIN6	93	42.675	ENSMZEG00005025053	gemin6	90	42.675	Maylandia_zebra
ENSG00000152147	GEMIN6	100	60.479	ENSMGAG00000007412	GEMIN6	100	60.479	Meleagris_gallopavo
ENSG00000152147	GEMIN6	100	76.000	ENSMICG00000030665	-	100	76.000	Microcebus_murinus
ENSG00000152147	GEMIN6	100	93.413	ENSMICG00000044164	-	100	93.413	Microcebus_murinus
ENSG00000152147	GEMIN6	100	84.431	ENSMOCG00000020703	Gemin6	100	84.431	Microtus_ochrogaster
ENSG00000152147	GEMIN6	75	44.444	ENSMMOG00000018333	gemin6	83	44.444	Mola_mola
ENSG00000152147	GEMIN6	99	80.120	ENSMODG00000008690	GEMIN6	100	80.120	Monodelphis_domestica
ENSG00000152147	GEMIN6	94	47.771	ENSMALG00000004049	gemin6	93	47.771	Monopterus_albus
ENSG00000152147	GEMIN6	100	85.629	ENSMUSG00000055760	Gemin6	100	85.629	Mus_musculus
ENSG00000152147	GEMIN6	100	85.629	MGP_PahariEiJ_G0020893	Gemin6	100	85.629	Mus_pahari
ENSG00000152147	GEMIN6	100	85.030	MGP_SPRETEiJ_G0022819	Gemin6	100	85.030	Mus_spretus
ENSG00000152147	GEMIN6	100	92.216	ENSMPUG00000010434	GEMIN6	100	92.216	Mustela_putorius_furo
ENSG00000152147	GEMIN6	99	87.952	ENSMLUG00000014772	GEMIN6	99	87.952	Myotis_lucifugus
ENSG00000152147	GEMIN6	100	86.826	ENSNGAG00000010184	Gemin6	94	86.826	Nannospalax_galili
ENSG00000152147	GEMIN6	93	42.675	ENSNBRG00000021753	gemin6	90	42.675	Neolamprologus_brichardi
ENSG00000152147	GEMIN6	100	98.802	ENSNLEG00000033616	GEMIN6	100	98.802	Nomascus_leucogenys
ENSG00000152147	GEMIN6	100	79.762	ENSMEUG00000010347	GEMIN6	100	79.762	Notamacropus_eugenii
ENSG00000152147	GEMIN6	74	84.677	ENSOPRG00000011593	-	100	84.677	Ochotona_princeps
ENSG00000152147	GEMIN6	100	85.629	ENSOPRG00000010256	-	100	85.629	Ochotona_princeps
ENSG00000152147	GEMIN6	100	80.240	ENSODEG00000011245	GEMIN6	94	80.240	Octodon_degus
ENSG00000152147	GEMIN6	93	42.949	ENSONIG00000019837	gemin6	93	42.949	Oreochromis_niloticus
ENSG00000152147	GEMIN6	75	71.200	ENSOANG00000003420	GEMIN6	100	71.200	Ornithorhynchus_anatinus
ENSG00000152147	GEMIN6	100	92.216	ENSOCUG00000015599	GEMIN6	82	92.216	Oryctolagus_cuniculus
ENSG00000152147	GEMIN6	95	38.365	ENSORLG00000025034	gemin6	92	38.994	Oryzias_latipes
ENSG00000152147	GEMIN6	94	40.764	ENSOMEG00000007793	gemin6	83	40.764	Oryzias_melastigma
ENSG00000152147	GEMIN6	100	89.222	ENSOGAG00000010172	GEMIN6	100	89.222	Otolemur_garnettii
ENSG00000152147	GEMIN6	100	88.623	ENSOARG00000008751	GEMIN6	100	88.623	Ovis_aries
ENSG00000152147	GEMIN6	100	99.401	ENSPPAG00000036509	GEMIN6	100	99.401	Pan_paniscus
ENSG00000152147	GEMIN6	100	89.222	ENSPPRG00000003704	GEMIN6	100	89.222	Panthera_pardus
ENSG00000152147	GEMIN6	100	90.419	ENSPTIG00000005586	GEMIN6	100	90.419	Panthera_tigris_altaica
ENSG00000152147	GEMIN6	100	100.000	ENSPTRG00000011852	GEMIN6	100	100.000	Pan_troglodytes
ENSG00000152147	GEMIN6	100	98.204	ENSPANG00000011066	GEMIN6	100	98.204	Papio_anubis
ENSG00000152147	GEMIN6	97	54.321	ENSPKIG00000017473	gemin6	97	54.321	Paramormyrops_kingsleyae
ENSG00000152147	GEMIN6	100	70.060	ENSPSIG00000004613	GEMIN6	100	70.060	Pelodiscus_sinensis
ENSG00000152147	GEMIN6	100	85.629	ENSPEMG00000014421	Gemin6	100	85.629	Peromyscus_maniculatus_bairdii
ENSG00000152147	GEMIN6	96	39.286	ENSPMAG00000005006	GEMIN6	93	39.286	Petromyzon_marinus
ENSG00000152147	GEMIN6	100	82.635	ENSPCIG00000020697	-	57	82.635	Phascolarctos_cinereus
ENSG00000152147	GEMIN6	95	42.500	ENSPFOG00000008882	gemin6	62	42.767	Poecilia_formosa
ENSG00000152147	GEMIN6	95	42.500	ENSPLAG00000011142	gemin6	78	42.500	Poecilia_latipinna
ENSG00000152147	GEMIN6	95	42.500	ENSPMEG00000019224	gemin6	63	42.500	Poecilia_mexicana
ENSG00000152147	GEMIN6	93	41.401	ENSPREG00000006140	gemin6	86	41.401	Poecilia_reticulata
ENSG00000152147	GEMIN6	100	99.401	ENSPPYG00000012479	GEMIN6	100	99.401	Pongo_abelii
ENSG00000152147	GEMIN6	64	75.701	ENSPCAG00000002685	-	99	75.701	Procavia_capensis
ENSG00000152147	GEMIN6	100	92.814	ENSPVAG00000012079	GEMIN6	100	92.814	Pteropus_vampyrus
ENSG00000152147	GEMIN6	93	42.675	ENSPNYG00000017043	gemin6	90	42.675	Pundamilia_nyererei
ENSG00000152147	GEMIN6	92	50.000	ENSPNAG00000012548	gemin6	87	50.000	Pygocentrus_nattereri
ENSG00000152147	GEMIN6	100	84.431	ENSRNOG00000027332	Gemin6	100	84.431	Rattus_norvegicus
ENSG00000152147	GEMIN6	100	98.802	ENSRBIG00000041939	GEMIN6	100	98.802	Rhinopithecus_bieti
ENSG00000152147	GEMIN6	100	98.204	ENSRROG00000041365	GEMIN6	100	98.204	Rhinopithecus_roxellana
ENSG00000152147	GEMIN6	100	98.204	ENSSBOG00000019013	GEMIN6	100	98.204	Saimiri_boliviensis_boliviensis
ENSG00000152147	GEMIN6	100	80.240	ENSSHAG00000015830	GEMIN6	100	80.240	Sarcophilus_harrisii
ENSG00000152147	GEMIN6	97	53.086	ENSSFOG00015021904	gemin6	98	53.086	Scleropages_formosus
ENSG00000152147	GEMIN6	95	47.799	ENSSMAG00000021084	gemin6	94	47.799	Scophthalmus_maximus
ENSG00000152147	GEMIN6	82	48.175	ENSSDUG00000021356	GEMIN6	83	48.175	Seriola_dumerili
ENSG00000152147	GEMIN6	94	47.134	ENSSLDG00000021483	gemin6	83	47.134	Seriola_lalandi_dorsalis
ENSG00000152147	GEMIN6	74	73.228	ENSSARG00000002420	GEMIN6	100	73.228	Sorex_araneus
ENSG00000152147	GEMIN6	99	66.667	ENSSPUG00000006725	GEMIN6	99	66.667	Sphenodon_punctatus
ENSG00000152147	GEMIN6	100	92.216	ENSSSCG00000008482	GEMIN6	100	92.216	Sus_scrofa
ENSG00000152147	GEMIN6	98	58.282	ENSTGUG00000002093	GEMIN6	98	58.282	Taeniopygia_guttata
ENSG00000152147	GEMIN6	95	44.654	ENSTRUG00000021447	gemin6	89	44.654	Takifugu_rubripes
ENSG00000152147	GEMIN6	94	46.497	ENSTNIG00000000221	gemin6	88	46.497	Tetraodon_nigroviridis
ENSG00000152147	GEMIN6	100	91.018	ENSTBEG00000005016	GEMIN6	100	91.018	Tupaia_belangeri
ENSG00000152147	GEMIN6	95	89.937	ENSTTRG00000014326	GEMIN6	100	89.937	Tursiops_truncatus
ENSG00000152147	GEMIN6	100	91.617	ENSUAMG00000025053	GEMIN6	100	91.617	Ursus_americanus
ENSG00000152147	GEMIN6	100	91.617	ENSUMAG00000013522	GEMIN6	100	91.617	Ursus_maritimus
ENSG00000152147	GEMIN6	100	91.617	ENSVVUG00000018764	GEMIN6	100	91.617	Vulpes_vulpes
ENSG00000152147	GEMIN6	98	59.756	ENSXETG00000009023	gemin6	94	59.756	Xenopus_tropicalis
ENSG00000152147	GEMIN6	93	42.038	ENSXCOG00000010839	gemin6	80	42.038	Xiphophorus_couchianus
ENSG00000152147	GEMIN6	93	42.038	ENSXMAG00000014191	gemin6	80	42.038	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000245	spliceosomal complex assembly	-	IEA	Process
GO:0000387	spliceosomal snRNP assembly	18984161.	IDA	Process
GO:0000387	spliceosomal snRNP assembly	11748230.	TAS	Process
GO:0000398	mRNA splicing, via spliceosome	11748230.	TAS	Process
GO:0005515	protein binding	11748230.12065586.15939020.16189514.22190034.25416956.26496610.	IPI	Function
GO:0005654	nucleoplasm	11748230.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	11748230.	IDA	Component
GO:0005829	cytosol	18984161.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0016604	nuclear body	11748230.	IDA	Component
GO:0032797	SMN complex	18984161.	IDA	Component
GO:0034719	SMN-Sm protein complex	18984161.	IDA	Component
GO:0051170	import into nucleus	-	TAS	Process
GO:0097504	Gemini of coiled bodies	20513430.	IDA	Component