EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000152464 (Gene tree)
Gene ID: 10557
Gene Symbol: RPP38
Alias: N
Full Name: ribonuclease P/MRP subunit p38
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 42,639 bases
Position: chr10:15,097,180-15,139,818
Accession: 30329
RBP type: canonical RBP
Summary: (Ribonuclease P/MRP Subunit P38) is a Protein Coding gene. Among its related pathways are Integrated Breast Cancer Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include ribonuclease P activity.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000367439	Ribosomal_L7Ae	PF01248.26	1.3e-15	1	1
ENSP00000367444	Ribosomal_L7Ae	PF01248.26	1.3e-15	1	1
ENSP00000367445	Ribosomal_L7Ae	PF01248.26	1.3e-15	1	1
ENSP00000478982	Ribosomal_L7Ae	PF01248.26	1.3e-15	1	1
ENSP00000402635	Ribosomal_L7Ae	PF01248.26	8.2e-13	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
15613537	3D models of yeast RNase P/MRP proteins Rpp1p and Pop3p.	RNA	2005 Feb	Dlakic M	-
16998185	Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes.	Nucleic Acids Res	2006	Rosenblad MA	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000378203	RPP38-204	1296	XM_017015480	ENSP00000367445	283 (aa)	XP_016870969	P78345
ENST00000378202	RPP38-203	1030	XM_006717364	ENSP00000367444	283 (aa)	XP_006717427	P78345
ENST00000378201	RPP38-202	833	-	ENSP00000367443	145 (aa)	-	Q5VUC9
ENST00000441850	RPP38-205	863	-	ENSP00000402635	168 (aa)	-	Q5VUC3
ENST00000378197	RPP38-201	1457	XM_006717363	ENSP00000367439	283 (aa)	XP_006717426	P78345
ENST00000451677	RPP38-206	323	-	-	- (aa)	-	-
ENST00000616640	RPP38-207	1537	XM_011519293	ENSP00000478982	283 (aa)	XP_011517595	P78345

Gene Model

Click here to download ENSG00000152464's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG
hsa03013	RNA transport	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000152464's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000152464	RPP38	99	46.988	ENSAPOG00000001240	rpp38	96	44.086	Acanthochromis_polyacanthus
ENSG00000152464	RPP38	100	79.762	ENSAMEG00000018832	RPP38	100	79.505	Ailuropoda_melanoleuca
ENSG00000152464	RPP38	86	49.669	ENSACIG00000011592	rpp38	92	42.697	Amphilophus_citrinellus
ENSG00000152464	RPP38	99	45.783	ENSAOCG00000017293	rpp38	97	43.643	Amphiprion_ocellaris
ENSG00000152464	RPP38	99	46.386	ENSAPEG00000002315	rpp38	96	45.683	Amphiprion_percula
ENSG00000152464	RPP38	99	48.193	ENSATEG00000000731	rpp38	98	42.806	Anabas_testudineus
ENSG00000152464	RPP38	95	54.321	ENSAPLG00000002054	RPP38	96	51.986	Anas_platyrhynchos
ENSG00000152464	RPP38	99	48.256	ENSACLG00000016958	rpp38	99	42.958	Astatotilapia_calliptera
ENSG00000152464	RPP38	99	48.256	ENSACLG00000016962	rpp38	99	42.606	Astatotilapia_calliptera
ENSG00000152464	RPP38	90	48.344	ENSAMXG00000025023	rpp38	98	44.765	Astyanax_mexicanus
ENSG00000152464	RPP38	100	73.498	ENSBTAG00000007702	RPP38	100	73.498	Bos_taurus
ENSG00000152464	RPP38	100	77.381	ENSCAFG00000024373	RPP38	100	75.265	Canis_familiaris
ENSG00000152464	RPP38	100	77.381	ENSCAFG00020008008	RPP38	100	75.265	Canis_lupus_dingo
ENSG00000152464	RPP38	100	74.205	ENSCHIG00000012484	RPP38	100	74.205	Capra_hircus
ENSG00000152464	RPP38	100	77.381	ENSCPOG00000003981	RPP38	100	76.408	Cavia_porcellus
ENSG00000152464	RPP38	100	77.465	ENSCLAG00000010194	RPP38	100	77.465	Chinchilla_lanigera
ENSG00000152464	RPP38	100	93.286	ENSCSAG00000019055	RPP38	100	93.286	Chlorocebus_sabaeus
ENSG00000152464	RPP38	100	83.929	ENSCHOG00000004335	RPP38	100	83.451	Choloepus_hoffmanni
ENSG00000152464	RPP38	100	75.000	ENSCGRG00001001395	Rpp38	100	76.140	Cricetulus_griseus_chok1gshd
ENSG00000152464	RPP38	100	75.000	ENSCGRG00000017441	Rpp38	100	76.140	Cricetulus_griseus_crigri
ENSG00000152464	RPP38	99	44.970	ENSCSEG00000001721	rpp38	99	40.138	Cynoglossus_semilaevis
ENSG00000152464	RPP38	100	46.154	ENSCVAG00000001676	rpp38	97	42.808	Cyprinodon_variegatus
ENSG00000152464	RPP38	88	50.336	ENSDARG00000040350	rpp38	96	45.756	Danio_rerio
ENSG00000152464	RPP38	100	82.143	ENSDNOG00000040314	RPP38	100	79.859	Dasypus_novemcinctus
ENSG00000152464	RPP38	100	72.619	ENSDORG00000009783	Rpp38	100	69.014	Dipodomys_ordii
ENSG00000152464	RPP38	100	77.381	ENSETEG00000002839	RPP38	100	75.000	Echinops_telfairi
ENSG00000152464	RPP38	100	79.167	ENSEASG00005019783	RPP38	98	78.853	Equus_asinus_asinus
ENSG00000152464	RPP38	100	72.085	ENSEEUG00000014677	RPP38	100	72.085	Erinaceus_europaeus
ENSG00000152464	RPP38	88	47.712	ENSELUG00000010160	rpp38	94	44.056	Esox_lucius
ENSG00000152464	RPP38	100	75.618	ENSFCAG00000022449	RPP38	100	75.618	Felis_catus
ENSG00000152464	RPP38	95	55.000	ENSFALG00000014804	RPP38	94	52.128	Ficedula_albicollis
ENSG00000152464	RPP38	100	80.357	ENSFDAG00000018669	RPP38	100	78.521	Fukomys_damarensis
ENSG00000152464	RPP38	100	44.048	ENSFHEG00000013741	rpp38	100	42.857	Fundulus_heteroclitus
ENSG00000152464	RPP38	95	55.625	ENSGALG00000008794	RPP38	92	51.439	Gallus_gallus
ENSG00000152464	RPP38	98	47.561	ENSGACG00000009258	rpp38	97	48.503	Gasterosteus_aculeatus
ENSG00000152464	RPP38	99	48.193	ENSHBUG00000010937	rpp38	97	42.806	Haplochromis_burtoni
ENSG00000152464	RPP38	100	76.786	ENSHGLG00000012144	RPP38	99	76.786	Heterocephalus_glaber_female
ENSG00000152464	RPP38	88	43.243	ENSIPUG00000022879	rpp38	99	42.086	Ictalurus_punctatus
ENSG00000152464	RPP38	100	77.385	ENSSTOG00000025699	RPP38	98	77.385	Ictidomys_tridecemlineatus
ENSG00000152464	RPP38	100	79.167	ENSJJAG00000007523	Rpp38	100	75.789	Jaculus_jaculus
ENSG00000152464	RPP38	88	47.651	ENSKMAG00000003986	rpp38	89	42.857	Kryptolebias_marmoratus
ENSG00000152464	RPP38	93	49.057	ENSLBEG00000006853	rpp38	94	44.322	Labrus_bergylta
ENSG00000152464	RPP38	100	57.143	ENSLACG00000006502	RPP38	100	51.333	Latimeria_chalumnae
ENSG00000152464	RPP38	95	49.708	ENSLOCG00000018347	rpp38	94	49.281	Lepisosteus_oculatus
ENSG00000152464	RPP38	100	82.738	ENSLAFG00000000509	RPP38	100	80.634	Loxodonta_africana
ENSG00000152464	RPP38	100	92.933	ENSMMUG00000007679	RPP38	100	92.933	Macaca_mulatta
ENSG00000152464	RPP38	99	47.674	ENSMAMG00000012774	rpp38	96	44.286	Mastacembelus_armatus
ENSG00000152464	RPP38	99	48.256	ENSMZEG00005003200	rpp38	99	42.958	Maylandia_zebra
ENSG00000152464	RPP38	99	48.256	ENSMZEG00005003189	rpp38	97	42.806	Maylandia_zebra
ENSG00000152464	RPP38	95	54.938	ENSMGAG00000008217	RPP38	92	52.174	Meleagris_gallopavo
ENSG00000152464	RPP38	100	73.810	ENSMAUG00000003644	Rpp38	100	75.439	Mesocricetus_auratus
ENSG00000152464	RPP38	100	77.381	ENSMOCG00000007020	Rpp38	100	76.491	Microtus_ochrogaster
ENSG00000152464	RPP38	94	45.732	ENSMMOG00000003446	rpp38	94	41.818	Mola_mola
ENSG00000152464	RPP38	100	66.071	ENSMODG00000024091	RPP38	100	66.316	Monodelphis_domestica
ENSG00000152464	RPP38	90	42.949	ENSMALG00000002356	rpp38	93	41.132	Monopterus_albus
ENSG00000152464	RPP38	100	76.786	MGP_CAROLIEiJ_G0023133	Rpp38	100	76.140	Mus_caroli
ENSG00000152464	RPP38	100	76.190	ENSMUSG00000049950	Rpp38	100	75.789	Mus_musculus
ENSG00000152464	RPP38	100	76.842	MGP_PahariEiJ_G0019193	Rpp38	100	76.842	Mus_pahari
ENSG00000152464	RPP38	100	75.595	MGP_SPRETEiJ_G0024051	Rpp38	100	75.088	Mus_spretus
ENSG00000152464	RPP38	100	77.976	ENSMPUG00000018523	RPP38	99	76.512	Mustela_putorius_furo
ENSG00000152464	RPP38	100	81.548	ENSMLUG00000002153	RPP38	100	81.625	Myotis_lucifugus
ENSG00000152464	RPP38	100	78.571	ENSNGAG00000011066	Rpp38	100	75.789	Nannospalax_galili
ENSG00000152464	RPP38	99	48.256	ENSNBRG00000006994	rpp38	98	42.086	Neolamprologus_brichardi
ENSG00000152464	RPP38	99	47.093	ENSONIG00000020467	rpp38	96	42.294	Oreochromis_niloticus
ENSG00000152464	RPP38	100	77.381	ENSOCUG00000024367	-	100	75.000	Oryctolagus_cuniculus
ENSG00000152464	RPP38	100	77.381	ENSOCUG00000022768	-	100	76.056	Oryctolagus_cuniculus
ENSG00000152464	RPP38	88	45.455	ENSORLG00000009219	rpp38	96	39.858	Oryzias_latipes
ENSG00000152464	RPP38	88	47.712	ENSORLG00020011503	rpp38	90	40.520	Oryzias_latipes_hni
ENSG00000152464	RPP38	88	45.946	ENSORLG00015017702	rpp38	90	40.000	Oryzias_latipes_hsok
ENSG00000152464	RPP38	88	47.619	ENSOMEG00000005414	rpp38	99	39.456	Oryzias_melastigma
ENSG00000152464	RPP38	100	82.143	ENSOGAG00000008059	RPP38	100	81.979	Otolemur_garnettii
ENSG00000152464	RPP38	100	74.912	ENSOARG00000004534	RPP38	100	74.912	Ovis_aries
ENSG00000152464	RPP38	100	99.405	ENSPPAG00000041577	RPP38	91	98.940	Pan_paniscus
ENSG00000152464	RPP38	100	75.618	ENSPPRG00000015329	RPP38	100	75.618	Panthera_pardus
ENSG00000152464	RPP38	100	75.265	ENSPTIG00000007188	RPP38	100	75.265	Panthera_tigris_altaica
ENSG00000152464	RPP38	100	99.405	ENSPTRG00000002318	RPP38	91	98.587	Pan_troglodytes
ENSG00000152464	RPP38	90	50.943	ENSPKIG00000025652	rpp38	93	44.086	Paramormyrops_kingsleyae
ENSG00000152464	RPP38	95	60.625	ENSPSIG00000001527	RPP38	98	57.193	Pelodiscus_sinensis
ENSG00000152464	RPP38	100	76.842	ENSPEMG00000008375	Rpp38	100	78.246	Peromyscus_maniculatus_bairdii
ENSG00000152464	RPP38	100	68.421	ENSPCIG00000009096	RPP38	94	68.070	Phascolarctos_cinereus
ENSG00000152464	RPP38	61	45.109	ENSPFOG00000016823	rpp38	82	45.109	Poecilia_formosa
ENSG00000152464	RPP38	88	44.218	ENSPLAG00000007626	rpp38	98	40.909	Poecilia_latipinna
ENSG00000152464	RPP38	88	40.136	ENSPMEG00000020392	rpp38	93	38.148	Poecilia_mexicana
ENSG00000152464	RPP38	100	42.262	ENSPREG00000017744	rpp38	97	40.351	Poecilia_reticulata
ENSG00000152464	RPP38	100	98.810	ENSPPYG00000002113	RPP38	100	98.233	Pongo_abelii
ENSG00000152464	RPP38	100	79.167	ENSPVAG00000007155	RPP38	100	79.505	Pteropus_vampyrus
ENSG00000152464	RPP38	99	48.256	ENSPNYG00000004293	rpp38	97	42.806	Pundamilia_nyererei
ENSG00000152464	RPP38	86	46.980	ENSPNAG00000010633	rpp38	99	44.245	Pygocentrus_nattereri
ENSG00000152464	RPP38	100	72.619	ENSRNOG00000038025	Rpp38	99	72.760	Rattus_norvegicus
ENSG00000152464	RPP38	100	68.772	ENSSHAG00000015529	RPP38	100	69.123	Sarcophilus_harrisii
ENSG00000152464	RPP38	96	47.531	ENSSMAG00000018276	rpp38	95	42.754	Scophthalmus_maximus
ENSG00000152464	RPP38	99	45.181	ENSSDUG00000001651	rpp38	98	43.110	Seriola_dumerili
ENSG00000152464	RPP38	99	45.181	ENSSLDG00000014355	rpp38	98	42.143	Seriola_lalandi_dorsalis
ENSG00000152464	RPP38	100	56.537	ENSSARG00000012099	RPP38	100	56.184	Sorex_araneus
ENSG00000152464	RPP38	93	61.146	ENSSPUG00000008560	-	97	53.986	Sphenodon_punctatus
ENSG00000152464	RPP38	99	61.677	ENSSPUG00000018363	-	99	56.643	Sphenodon_punctatus
ENSG00000152464	RPP38	100	61.538	ENSSPUG00000005237	-	100	57.292	Sphenodon_punctatus
ENSG00000152464	RPP38	99	46.386	ENSSPAG00000020387	rpp38	96	44.604	Stegastes_partitus
ENSG00000152464	RPP38	100	72.028	ENSSSCG00000027110	RPP38	100	72.028	Sus_scrofa
ENSG00000152464	RPP38	95	52.500	ENSTGUG00000001366	RPP38	97	50.355	Taeniopygia_guttata
ENSG00000152464	RPP38	88	41.667	ENSTRUG00000019933	-	94	42.446	Takifugu_rubripes
ENSG00000152464	RPP38	100	46.471	ENSTNIG00000001334	rpp38	96	42.705	Tetraodon_nigroviridis
ENSG00000152464	RPP38	100	73.852	ENSTTRG00000004420	RPP38	100	73.852	Tursiops_truncatus
ENSG00000152464	RPP38	100	79.167	ENSUAMG00000002618	RPP38	100	79.152	Ursus_americanus
ENSG00000152464	RPP38	100	77.817	ENSUMAG00000012382	RPP38	100	78.873	Ursus_maritimus
ENSG00000152464	RPP38	100	76.786	ENSVVUG00000005272	RPP38	100	74.912	Vulpes_vulpes
ENSG00000152464	RPP38	95	53.704	ENSXETG00000003419	rpp38	97	48.043	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001650	fibrillar center	-	IDA	Component
GO:0001682	tRNA 5'-leader removal	30454648.	IDA	Process
GO:0001682	tRNA 5'-leader removal	-	TAS	Process
GO:0004526	ribonuclease P activity	30454648.	IDA	Function
GO:0005515	protein binding	15096576.17474147.	IPI	Function
GO:0005634	nucleus	9630247.	TAS	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005655	nucleolar ribonuclease P complex	9630247.	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0030681	multimeric ribonuclease P complex	30454648.	IDA	Component
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	-	IEA	Process