EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000152601 (Gene tree)
Gene ID: 4154
Gene Symbol: MBNL1
Alias: KIAA0428|EXP42|EXP40|EXP35|EXP|MBNL
Full Name: muscleblind like splicing regulator 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 221,953 bases
Position: chr3:152,243,828-152,465,780
Accession: 6923
RBP type: canonical RBP
Summary: This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000418427	zf-CCCH	PF00642.24	1.1e-09	1	1
ENSP00000418109	zf-CCCH	PF00642.24	1.3e-09	1	1
ENSP00000319374	zf-CCCH	PF00642.24	1.3e-09	1	1
ENSP00000418876	zf-CCCH	PF00642.24	1.3e-09	1	1
ENSP00000417630	zf-CCCH	PF00642.24	1.3e-09	1	1
ENSP00000437491	zf-CCCH	PF00642.24	1.3e-09	1	1
ENSP00000350064	zf-CCCH	PF00642.24	1.5e-09	1	1
ENSP00000420103	zf-CCCH	PF00642.24	1.5e-09	1	1
ENSP00000420327	zf-CCCH	PF00642.24	1.8e-09	1	1
ENSP00000347637	zf-CCCH	PF00642.24	2.6e-09	1	1
ENSP00000319429	zf-CCCH	PF00642.24	2.7e-09	1	1
ENSP00000282486	zf-CCCH	PF00642.24	3.1e-09	1	1
ENSP00000418108	zf-CCCH	PF00642.24	3.1e-09	1	1
ENSP00000282488	zf-CCCH	PF00642.24	3.5e-09	1	1
ENSP00000419347	zf-CCCH	PF00642.24	2.5e-07	1	1
ENSP00000418508	zf-CCCH	PF00642.24	3.3e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
24781112	Development of an AP-FRET based analysis for characterizing RNA-protein interactions in myotonic dystrophy (DM1).	PLoS One	2014 Apr 29	Rehman S	doi: 10.1371/journal.pone.0095957
19909263	Pathogenic mechanisms of myotonic dystrophy.	Biochem Soc Trans	2009 Dec	Lee JE	doi: 10.1042/BST0371281.
21889481	RNA Foci, CUGBP1, and ZNF9 are the primary targets of the mutant CUG and CCUG repeats expanded in myotonic dystrophies type 1 and type 2.	Am J Pathol	2011 Nov	Jones K	doi: 10.1016/j.ajpath.2011.07.013
24377303	Examining the interactions of the splicing factor MBNL1 with target RNA sequences via a label-free, multiplex method.	Anal Chem	2014 Jan 21	Yadav AR	doi: 10.1021/ac402603j
23796888	Molecular mechanisms of muscle atrophy in myotonic dystrophies.	Int J Biochem Cell Biol	2013 Oct	Timchenko L	doi: 10.1016/j.biocel.2013.06.010
31323950	Short Tandem Repeat Expansions and RNA-Mediated Pathogenesis in Myotonic Dystrophy.	Int J Mol Sci	2019 Jul 9	Sznajder LJ	doi: 10.3390/ijms20133365.
12915312	Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3.	Gene Expr Patterns	2003 Aug	Kanadia RN	-
16878132	Reversible model of RNA toxicity and cardiac conduction defects in myotonic dystrophy.	Nat Genet	2006 Sep	Mahadevan MS	-
20186122	Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients.	EMBO J	2010 Apr 7	Sellier C	doi: 10.1038/emboj.2010.21
19470458	The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing.	Proc Natl Acad Sci U S A	2009 Jun 9	Warf MB	doi: 10.1073/pnas.0900342106
18557632	RNA binding specificity of Drosophila muscleblind.	Biochemistry	2008 Jul 8	Goers ES	doi: 10.1021/bi702252d
18213585	Muscleblind-like 2 (Mbnl2) -deficient mice as a model for myotonic dystrophy.	Dev Dyn	2008 Feb	Hao M	doi: 10.1002/dvdy.21428.
22218462	Two high-throughput screening assays for aberrant RNA-protein interactions in myotonic dystrophy type 1.	Anal Bioanal Chem	2012 Feb	Chen CZ	doi: 10.1007/s00216-011-5604-0
23308382	Systemic delivery of a Peptide-linked morpholino oligonucleotide neutralizes mutant RNA toxicity in a mouse model of myotonic dystrophy.	Nucleic Acid Ther	2013 Apr	Leger AJ	doi: 10.1089/nat.2012.0404
22106026	MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.	Chembiochem	2012 Jan 2	Fu Y	doi: 10.1002/cbic.201100487
21685920	Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy.	Nat Struct Mol Biol	2011 Jun 19	Rau F	doi: 10.1038/nsmb.2067.
25504326	Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics.	Dev Dyn	2015 Mar	Chau A	doi: 10.1002/dvdy.24240
25274774	Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins.	Hum Mol Genet	2015 Feb 1	Kino Y	doi: 10.1093/hmg/ddu492
25239918	Development of a Drosophila melanogaster spliceosensor system for in vivo high-throughput screening in myotonic dystrophy type 1.	Dis Model Mech	2014 Nov	Garcia-Alcover I	doi: 10.1242/dmm.016592
25183524	MBNL proteins and their target RNAs, interaction and splicing regulation.	Nucleic Acids Res	2014	Konieczny P	doi: 10.1093/nar/gku767
24878509	LDB3 splicing abnormalities are specific to skeletal muscles of patients with myotonic dystrophy type 1 and alter its PKC binding affinity.	Neurobiol Dis	2014 Sep	Yamashita Y	doi: 10.1016/j.nbd.2014.05.026
24837674	RNA Bind-n-Seq: quantitative assessment of the sequence and structural binding specificity of RNA binding proteins.	Mol Cell	2014 Jun 5	Lambert N	doi: 10.1016/j.molcel.2014.04.016
24376746	Overexpression of CUGBP1 in skeletal muscle from adult classic myotonic dystrophy type 1 but not from myotonic dystrophy type 2.	PLoS One	2013 Dec 20	Cardani R	doi: 10.1371/journal.pone.0083777
24028068	Reducing levels of toxic RNA with small molecules.	ACS Chem Biol	2013 Nov 15	Coonrod LA	doi: 10.1021/cb400431f
24001600	Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicity.	Hum Mol Genet	2014 Jan 15	Kim YK	doi: 10.1093/hmg/ddt419
23511971	MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3.	Nucleic Acids Res	2013 May	Gooding C	doi: 10.1093/nar/gkt168
26217220	Muscle wasting in myotonic dystrophies: a model of premature aging.	Front Aging Neurosci	2015 Jul 9	Mateos-Aierdi AJ	doi: 10.3389/fnagi.2015.00125
29309648	An engineered RNA binding protein with improved splicing regulation.	Nucleic Acids Res	2018 Apr 6	Hale MA	doi: 10.1093/nar/gkx1304.
29687899	Myotonic Dystrophy and Developmental Regulation of RNA Processing.	Compr Physiol	2018 Mar 25	Thomas JD	doi: 10.1002/cphy.c170002.
29955876	MBNL splicing activity depends on RNA binding site structural context.	Nucleic Acids Res	2018 Sep 28	Taylor K	doi: 10.1093/nar/gky565.
30997488	MBNL1 overexpression is not sufficient to rescue the phenotypes in a mouse model of RNA toxicity.	Hum Mol Genet	2019 Jul 15	Yadava RS	doi: 10.1093/hmg/ddz065.
23130637	Rational design of bioactive, modularly assembled aminoglycosides targeting the RNA that causes myotonic dystrophy type 1.	ACS Chem Biol	2012 Dec 21	Childs-Disney JL	doi: 10.1021/cb3001606
20502647	HTS-Compatible Patient-Derived Cell-Based Assay to Identify Small Molecule Modulators of Aberrant Splicing in Myotonic Dystrophy Type 1.	Curr Chem Genomics	2010 Mar 19	O'Leary DA	doi: 10.2174/1875397301004010009.
16550919	Regulation of splicing by MBNL and CELF family of RNA-binding protein.	Acta Myol	2005 Oct	Ishiura S	-
11433021	In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts.	Nucleic Acids Res	2001 Jul 1	Fardaei M	-
10970838	Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.	EMBO J	2000 Sep 1	Miller JW	-
14722159	Muscleblind protein, MBNL1/EXP, binds specifically to CHHG repeats.	Hum Mol Genet	2004 Mar 1	Kino Y	-
23118342	Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model.	Dis Model Mech	2013 Jan	Llamusi B	doi: 10.1242/dmm.009563
20071745	MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing.	Nucleic Acids Res	2010 Apr	Goers ES	doi: 10.1093/nar/gkp1209
20051426	Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1.	Hum Mol Genet	2010 Mar 15	Koshelev M	doi: 10.1093/hmg/ddp570
20009516	Conserved developmental alternative splicing of muscleblind-like (MBNL) transcripts regulates MBNL localization and activity.	RNA Biol	2010 Jan-Feb	Terenzi F	-
19864209	RNA/MBNL1-containing foci in myoblast nuclei from patients affected by myotonic dystrophy type 2: an immunocytochemical study.	Eur J Histochem	2009 Sep 23	Perdoni F	-
19177353	Solution structure of the RNA binding domain in the human muscleblind-like protein 2.	Protein Sci	2009 Jan	He F	doi: 10.1002/pro.17.
18998634	Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA-MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1).	J Am Chem Soc	2008 Dec 3	Gareiss PC	doi: 10.1021/ja804398y.
18653337	A putative role of ribonuclear inclusions and MBNL1 in the impairment of gallbladder smooth muscle contractility with cholelithiasis in myotonic dystrophy type 1.	Neuromuscul Disord	2008 Aug	Cardani R	doi: 10.1016/j.nmd.2008.06.366
18606240	Zebrafish muscleblind-like genes: identification, structural features and expression.	Comp Biochem Physiol B Biochem Mol Biol	2008 Sep	Liu YF	doi: 10.1016/j.cbpb.2008.06.005
18095352	Developmental regulation of muscleblind-like (MBNL) gene expression in the chicken embryo retina.	Dev Dyn	2008 Jan	Huang H	-
22890842	Combinatorial mutagenesis of MBNL1 zinc fingers elucidates distinct classes of regulatory events.	Mol Cell Biol	2012 Oct	Purcell J	-
22892953	Myotonic dystrophy: is a narrow focus obscuring the rest of the field?	Curr Opin Neurol	2012 Oct	Mahadevan MS	doi: 10.1097/WCO.0b013e328357b0d9.
22901804	Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins.	Cell	2012 Aug 17	Wang ET	doi: 10.1016/j.cell.2012.06.041.
17702765	Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs.	Nucleic Acids Res	2007	Yuan Y	-
22866814	Loss of muscleblind-like 1 promotes invasive mesenchyme formation in endocardial cushions by stimulating autocrine TGFβ3.	BMC Dev Biol	2012 Aug 6	LeMasters KE	doi: 10.1186/1471-213X-12-22.
17331722	Expression of MBNL and CELF mRNA transcripts in muscles with myotonic dystrophy.	Neuromuscul Disord	2007 Apr	Nezu Y	-
22355723	CUGBP1 and MBNL1 preferentially bind to 3' UTRs and facilitate mRNA decay.	Sci Rep	2012	Masuda A	doi: 10.1038/srep00209
21763392	Gain of RNA function in pathological cases: Focus on myotonic dystrophy.	Biochimie	2011 Nov	Klein AF	doi: 10.1016/j.biochi.2011.06.028
21730182	In vivo discovery of a peptide that prevents CUG-RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models.	Proc Natl Acad Sci U S A	2011 Jul 19	Garcia-Lopez A	doi: 10.1073/pnas.1018213108
21529292	Monoclonal antibodies against Muscleblind-like 3, a protein with punctate nuclear localization.	Hybridoma (Larchmt)	2011 Apr	Lee KS	doi: 10.1089/hyb.2010.0082.
21548961	The four Zn fingers of MBNL1 provide a flexible platform for recognition of its RNA binding elements.	BMC Mol Biol	2011 May 6	Cass D	doi: 10.1186/1471-2199-12-20.
20885816	Myotonic dystrophies 1 and 2: complex diseases with complex mechanisms.	Curr Genomics	2010 Apr	Schoser B	doi: 10.2174/138920210790886844.
23196502	[Misregulation of alternative splicing and microRNA processing in DM1 pathogenesis].	Rinsho Shinkeigaku	2012	Furling D	-
20709755	RNA-binding protein Muscleblind-like 3 (MBNL3) disrupts myocyte enhancer factor 2 (Mef2) {beta}-exon splicing.	J Biol Chem	2010 Oct 29	Lee KS	doi: 10.1074/jbc.M110.124255
25305073	A fly model for the CCUG-repeat expansion of myotonic dystrophy type 2 reveals a novel interaction with MBNL1.	Hum Mol Genet	2015 Feb 15	Yu Z	doi: 10.1093/hmg/ddu507
24752171	Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development.	Nat Commun	2014 Apr 22	Giudice J	doi: 10.1038/ncomms4603.
24373687	Dissecting domains necessary for activation and repression of splicing by Muscleblind-like protein 1.	BMC Mol Biol	2013 Dec 27	Edge C	doi: 10.1186/1471-2199-14-29.
24039817	Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).	PLoS One	2013 Sep 5	Gladman JT	doi: 10.1371/journal.pone.0072907
27657532	Disease Phenotypes in a Mouse Model of RNA Toxicity Are Independent of Protein Kinase Cα and Protein Kinase Cβ.	PLoS One	2016 Sep 22	Kim YK	doi: 10.1371/journal.pone.0163325
23739326	MBNL proteins repress ES-cell-specific alternative splicing and reprogramming.	Nature	2013 Jun 13	Han H	doi: 10.1038/nature12270
23444380	mTOR-dependent proliferation defect in human ES-derived neural stem cells affected by myotonic dystrophy type 1.	J Cell Sci	2013 Apr 15	Denis JA	doi: 10.1242/jcs.116285
28130447	Pseudouridine Modification Inhibits Muscleblind-like 1 (MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility.	J Biol Chem	2017 Mar 10	deLorimier E	doi: 10.1074/jbc.M116.770768
23536431	Dysfunction of protein homeostasis in myotonic dystrophies.	Histol Histopathol	2013 Sep	Meola G	doi: 10.14670/HH-28.1089
27465358	Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins.	Mol Neurodegener	2016 Jul 28	Alves S	doi: 10.1186/s13024-016-0123-2.
26670661	MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response.	Nat Commun	2015 Dec 16	Davis J	doi: 10.1038/ncomms10084.
26621726	Reversion to an embryonic alternative splicing program enhances leukemia stem cell self-renewal.	Proc Natl Acad Sci U S A	2015 Dec 15	Holm F	doi: 10.1073/pnas.1506943112
26472242	Muscleblind-like 1 is required for normal heart valve development in vivo.	BMC Dev Biol	2015 Oct 15	Coram RJ	doi: 10.1186/s12861-015-0087-4.
25977444	The polymorphic terminal-loop of pre-miR-1307 binding with MBNL1 contributes to colorectal carcinogenesis via interference with Dicer1 recruitment.	Carcinogenesis	2015 Aug	Tang R	doi: 10.1093/carcin/bgv066
25883322	Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins.	Genome Res	2015 Jun	Wang ET	doi: 10.1101/gr.184390.114
25887157	Celf1 regulates cell cycle and is partially responsible for defective myoblast differentiation in myotonic dystrophy RNA toxicity.	Biochim Biophys Acta	2015 Jul	Peng X	doi: 10.1016/j.bbadis.2015.04.010
28535287	A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I.	Hum Mol Genet	2017 Aug 15	Zhang F	doi: 10.1093/hmg/ddx190.
28718627	Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.	Biochemistry	2017 Aug 15	Park S	doi: 10.1021/acs.biochem.7b00484
28955807	Splicing of human chloride channel 1.	Biochem Biophys Rep	2015 Nov 11	Nakamura T	doi: 10.1016/j.bbrep.2015.11.006
29716962	Bruno-3 regulates sarcomere component expression and contributes to muscle phenotypes of myotonic dystrophy type 1.	Dis Model Mech	2018 May 21	Picchio L	doi: 10.1242/dmm.031849.
29789616	rbFOX1/MBNL1 competition for CCUG RNA repeats bindingcontributes to myotonic dystrophy type1/type2 differences.	Nat Commun	2018 May 22	Sellier C	doi: 10.1038/s41467-018-04370-x.
29875359	Precise temporal regulation of alternative splicing during neural development.	Nat Commun	2018 Jun 6	Weyn-Vanhentenryck SM	doi: 10.1038/s41467-018-04559-0.
30256871	RNA/MBNL1-containing foci in myoblast nuclei from patients affected by myotonic dystrophy type 2: an immunocytochemical study.	Eur J Histochem	2009 Sep 30	Perdoni F	doi: 10.4081/ejh.2009.e18
30818081	Conserved functions of RNA-binding proteins in muscle.	Int J Biochem Cell Biol	2019 May	Nikonova E	doi: 10.1016/j.biocel.2019.02.008
31075282	Rationally designed small molecules targeting toxic CAG repeat RNA that causes Huntington's disease (HD) and spinocerebellar ataxia (SCAs).	Biochimie	2019 Aug	Khan E	doi: 10.1016/j.biochi.2019.05.001
22156369	New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats.	Nucleic Acids Res	2012 Apr	Laurent FX	doi: 10.1093/nar/gkr1228
19904940	Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: targeting the RNAs that cause myotonic muscular dystrophy.	J Am Chem Soc	2009 Dec 2	Lee MM	doi: 10.1021/ja906877y.
19608921	Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA.	Science	2009 Jul 17	Wheeler TM	doi: 10.1126/science.1173110.
19552411	Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.	J Am Chem Soc	2009 Jul 22	Pushechnikov A	doi: 10.1021/ja9020149.
19348464	Rational and modular design of potent ligands targeting the RNA that causes myotonic dystrophy 2.	ACS Chem Biol	2009 May 15	Lee MM	doi: 10.1021/cb900025w.
22371589	RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1.	Proc Natl Acad Sci U S A	2012 Mar 13	Lee JE	doi: 10.1073/pnas.1117019109
20603324	CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1.	Hum Mol Genet	2010 Sep 15	Ward AJ	doi: 10.1093/hmg/ddq277
26148061	Structural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs).	PLoS One	2015 Jul 6	Tawani A	doi: 10.1371/journal.pone.0131788
27720642	RNA Sequence Context Effects Measured InVitro Predict InVivo Protein Binding and Regulation.	Mol Cell	2016 Oct 20	Taliaferro JM	doi: 10.1016/j.molcel.2016.08.035
30606728	The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation.	Drug Metab Dispos	2019 Mar	Idris M	doi: 10.1124/dmd.118.085290

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000282486	MBNL1-201	6422	XM_005247461	ENSP00000282486	388 (aa)	XP_005247518	Q9NR56
ENST00000464596	MBNL1-212	989	XM_005247468	ENSP00000418109	329 (aa)	XP_005247525	H7C4T5
ENST00000460591	MBNL1-209	898	-	ENSP00000420680	155 (aa)	-	C9JCX1
ENST00000282488	MBNL1-202	6458	XM_005247457	ENSP00000282488	400 (aa)	XP_005247514	A0A0A0MQX8
ENST00000324196	MBNL1-203	5225	-	ENSP00000319374	340 (aa)	-	Q9NR56
ENST00000493459	MBNL1-220	4205	XM_011512848	ENSP00000419347	343 (aa)	XP_011511150	Q86VM6
ENST00000498502	MBNL1-223	5258	XM_005247467	ENSP00000420327	348 (aa)	XP_005247524	C9JP00
ENST00000461436	MBNL1-210	1681	-	-	- (aa)	-	-
ENST00000357472	MBNL1-206	5256	XM_005247465	ENSP00000350064	342 (aa)	XP_005247522	Q9NR56
ENST00000495875	MBNL1-221	545	-	ENSP00000417741	90 (aa)	-	C9J7P7
ENST00000492948	MBNL1-219	1054	-	ENSP00000420103	342 (aa)	-	Q9NR56
ENST00000324210	MBNL1-204	5465	XM_005247462	ENSP00000319429	382 (aa)	XP_005247519	Q9NR56
ENST00000545754	MBNL1-224	5147	XM_011512845	ENSP00000437491	314 (aa)	XP_011511147	Q9NR56
ENST00000463374	MBNL1-211	5092	XM_017006425	ENSP00000418108	388 (aa)	XP_016861914	Q9NR56
ENST00000485509	MBNL1-217	1023	-	ENSP00000418876	340 (aa)	-	Q9NR56
ENST00000497971	MBNL1-222	5051	-	-	- (aa)	-	-
ENST00000355460	MBNL1-205	5941	XM_005247463	ENSP00000347637	370 (aa)	XP_005247520	Q9NR56
ENST00000466565	MBNL1-214	1096	-	-	- (aa)	-	-
ENST00000478535	MBNL1-216	1451	-	ENSP00000418508	210 (aa)	-	H7C4Y1
ENST00000485910	MBNL1-218	4257	XM_011512846	ENSP00000418427	302 (aa)	XP_011511148	Q9NR56
ENST00000460166	MBNL1-208	552	-	-	- (aa)	-	-
ENST00000459747	MBNL1-207	594	-	ENSP00000417169	58 (aa)	-	C9J4T8
ENST00000477171	MBNL1-215	1039	-	-	- (aa)	-	-
ENST00000465907	MBNL1-213	945	-	ENSP00000417630	314 (aa)	-	Q9NR56

Gene Model

Click here to download ENSG00000152601's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000152601	Body Mass Index	6.49678632189978E-5	17903300
ENSG00000152601	Child Development Disorders, Pervasive	8.0233000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000152601	rs4472028	3	152335461	T	Type 2 diabetes	30054458	[0.031-0.059] unit increase	0.0453	EFO_0001360
ENSG00000152601	rs6784925	3	152305101	C	Heel bone mineral density	30598549	[0.0073-0.0145] unit increase	0.0108875	EFO_0009270
ENSG00000152601	rs13093352	3	152295225	G	Male-pattern baldness	30573740	[0.022-0.036] unit decrease	0.0290976	EFO_0007825
ENSG00000152601	rs2217083	3	152270138	?	Lung function (FVC)	30595370			EFO_0004312
ENSG00000152601	rs74497536	3	152300313	?	White blood cell count	30595370			EFO_0004308
ENSG00000152601	rs146975914	3	152258025	T	Pulse pressure	30578418	[0.37-0.75] mmHg decrease	0.5583	EFO_0005763
ENSG00000152601	rs7633673	3	152366454	A	Neuroticism	30643256	[0.0052-0.011] unit decrease	0.008128366	EFO_0007660
ENSG00000152601	rs7633673	3	152366454	A	Depressive symptoms	30643256	[0.0033-0.0071] unit decrease	0.005194133	EFO_0007006
ENSG00000152601	rs7633673	3	152366454	A	Well-being spectrum (multivariate analysis)	30643256	[0.0033-0.0069] unit decrease	0.005116514	EFO_0007869
ENSG00000152601	rs182314334	3	152286413	T	Prostate cancer	29892016	[1.06-1.12]	1.09	EFO_0001663

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000152601's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000152601	MBNL1	97	80.702	ENSG00000139793	MBNL2	93	83.621
ENSG00000152601	MBNL1	93	88.889	ENSG00000076770	MBNL3	95	68.548

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000152601	MBNL1	100	95.652	ENSAPOG00000022748	MBNL1	100	86.667	Acanthochromis_polyacanthus
ENSG00000152601	MBNL1	97	75.000	ENSAPOG00000005228	mbnl3	100	65.449	Acanthochromis_polyacanthus
ENSG00000152601	MBNL1	97	80.702	ENSAPOG00000023160	-	99	67.005	Acanthochromis_polyacanthus
ENSG00000152601	MBNL1	97	77.193	ENSAPOG00000007868	mbnl2	99	71.429	Acanthochromis_polyacanthus
ENSG00000152601	MBNL1	97	94.643	ENSAPOG00000023703	mbnl1	100	82.803	Acanthochromis_polyacanthus
ENSG00000152601	MBNL1	97	80.702	ENSAMEG00000003725	MBNL2	99	67.313	Ailuropoda_melanoleuca
ENSG00000152601	MBNL1	100	99.742	ENSAMEG00000008884	MBNL1	100	99.742	Ailuropoda_melanoleuca
ENSG00000152601	MBNL1	99	66.927	ENSAMEG00000011259	MBNL3	99	65.885	Ailuropoda_melanoleuca
ENSG00000152601	MBNL1	100	95.652	ENSACIG00000016141	MBNL1	100	85.570	Amphilophus_citrinellus
ENSG00000152601	MBNL1	97	77.193	ENSACIG00000020330	mbnl2	99	68.820	Amphilophus_citrinellus
ENSG00000152601	MBNL1	97	80.702	ENSACIG00000019146	-	99	66.301	Amphilophus_citrinellus
ENSG00000152601	MBNL1	97	94.643	ENSACIG00000004783	mbnl1	100	79.733	Amphilophus_citrinellus
ENSG00000152601	MBNL1	97	73.214	ENSACIG00000009919	mbnl3	90	66.667	Amphilophus_citrinellus
ENSG00000152601	MBNL1	97	92.857	ENSAOCG00000024412	mbnl1	99	87.826	Amphiprion_ocellaris
ENSG00000152601	MBNL1	97	80.702	ENSAOCG00000015492	-	99	65.354	Amphiprion_ocellaris
ENSG00000152601	MBNL1	97	77.193	ENSAOCG00000004268	mbnl2	99	69.600	Amphiprion_ocellaris
ENSG00000152601	MBNL1	100	95.652	ENSAOCG00000010557	MBNL1	100	86.667	Amphiprion_ocellaris
ENSG00000152601	MBNL1	97	75.000	ENSAOCG00000004789	mbnl3	100	65.449	Amphiprion_ocellaris
ENSG00000152601	MBNL1	97	92.857	ENSAPEG00000009298	mbnl1	99	87.826	Amphiprion_percula
ENSG00000152601	MBNL1	97	75.000	ENSAPEG00000009067	mbnl3	100	65.449	Amphiprion_percula
ENSG00000152601	MBNL1	100	95.652	ENSAPEG00000001271	MBNL1	100	86.667	Amphiprion_percula
ENSG00000152601	MBNL1	97	77.193	ENSAPEG00000003855	mbnl2	99	71.545	Amphiprion_percula
ENSG00000152601	MBNL1	97	80.702	ENSAPEG00000023468	-	99	67.259	Amphiprion_percula
ENSG00000152601	MBNL1	97	94.643	ENSATEG00000013371	mbnl1	99	88.696	Anabas_testudineus
ENSG00000152601	MBNL1	97	77.193	ENSATEG00000002926	mbnl2	99	70.543	Anabas_testudineus
ENSG00000152601	MBNL1	97	96.429	ENSATEG00000015283	MBNL1	100	86.305	Anabas_testudineus
ENSG00000152601	MBNL1	97	80.702	ENSATEG00000014258	-	99	66.298	Anabas_testudineus
ENSG00000152601	MBNL1	97	75.000	ENSATEG00000014871	mbnl3	100	65.169	Anabas_testudineus
ENSG00000152601	MBNL1	100	97.007	ENSAPLG00000012049	MBNL1	100	97.007	Anas_platyrhynchos
ENSG00000152601	MBNL1	100	100.000	ENSACAG00000029116	MBNL1	99	100.000	Anolis_carolinensis
ENSG00000152601	MBNL1	97	80.702	ENSACAG00000009557	MBNL3	100	68.468	Anolis_carolinensis
ENSG00000152601	MBNL1	97	80.702	ENSACAG00000000969	MBNL2	99	70.871	Anolis_carolinensis
ENSG00000152601	MBNL1	100	100.000	ENSANAG00000028111	MBNL1	100	100.000	Aotus_nancymaae
ENSG00000152601	MBNL1	79	85.106	ENSANAG00000026531	MBNL3	99	63.836	Aotus_nancymaae
ENSG00000152601	MBNL1	97	80.702	ENSANAG00000034762	MBNL2	93	83.621	Aotus_nancymaae
ENSG00000152601	MBNL1	97	78.947	ENSACLG00000007843	-	99	66.414	Astatotilapia_calliptera
ENSG00000152601	MBNL1	97	73.214	ENSACLG00000018199	mbnl3	100	66.011	Astatotilapia_calliptera
ENSG00000152601	MBNL1	97	94.643	ENSACLG00000027328	mbnl1	100	80.741	Astatotilapia_calliptera
ENSG00000152601	MBNL1	100	95.652	ENSACLG00000014489	MBNL1	100	85.995	Astatotilapia_calliptera
ENSG00000152601	MBNL1	97	77.193	ENSACLG00000027836	mbnl2	99	72.093	Astatotilapia_calliptera
ENSG00000152601	MBNL1	97	92.857	ENSAMXG00000011855	mbnl1	98	88.696	Astyanax_mexicanus
ENSG00000152601	MBNL1	93	76.364	ENSAMXG00000010312	-	99	59.847	Astyanax_mexicanus
ENSG00000152601	MBNL1	97	80.702	ENSAMXG00000042491	mbnl3	99	60.149	Astyanax_mexicanus
ENSG00000152601	MBNL1	97	80.702	ENSBTAG00000018313	MBNL2	99	73.969	Bos_taurus
ENSG00000152601	MBNL1	100	100.000	ENSBTAG00000004564	MBNL1	100	100.000	Bos_taurus
ENSG00000152601	MBNL1	90	76.364	ENSBTAG00000014088	MBNL3	99	61.290	Bos_taurus
ENSG00000152601	MBNL1	50	74.194	WBGene00019347	mbl-1	56	48.000	Caenorhabditis_elegans
ENSG00000152601	MBNL1	79	87.234	ENSCJAG00000004080	MBNL3	99	64.384	Callithrix_jacchus
ENSG00000152601	MBNL1	97	80.702	ENSCJAG00000004294	MBNL2	99	73.969	Callithrix_jacchus
ENSG00000152601	MBNL1	100	100.000	ENSCJAG00000040560	MBNL1	100	100.000	Callithrix_jacchus
ENSG00000152601	MBNL1	97	80.702	ENSCAFG00000005523	MBNL2	100	74.324	Canis_familiaris
ENSG00000152601	MBNL1	100	99.750	ENSCAFG00000008603	MBNL1	100	99.750	Canis_familiaris
ENSG00000152601	MBNL1	76	86.667	ENSCAFG00000018841	MBNL3	99	66.027	Canis_familiaris
ENSG00000152601	MBNL1	76	86.667	ENSCAFG00020000653	MBNL3	98	65.909	Canis_lupus_dingo
ENSG00000152601	MBNL1	97	80.702	ENSCAFG00020023874	MBNL2	99	74.302	Canis_lupus_dingo
ENSG00000152601	MBNL1	100	100.000	ENSCAFG00020004737	MBNL1	100	100.000	Canis_lupus_dingo
ENSG00000152601	MBNL1	100	100.000	ENSCHIG00000019308	MBNL1	100	99.750	Capra_hircus
ENSG00000152601	MBNL1	97	80.702	ENSCHIG00000022976	MBNL2	99	73.404	Capra_hircus
ENSG00000152601	MBNL1	88	79.630	ENSCHIG00000015570	MBNL3	99	62.634	Capra_hircus
ENSG00000152601	MBNL1	97	80.702	ENSTSYG00000004574	MBNL2	99	65.385	Carlito_syrichta
ENSG00000152601	MBNL1	100	99.355	ENSTSYG00000010491	MBNL1	100	100.000	Carlito_syrichta
ENSG00000152601	MBNL1	99	65.217	ENSTSYG00000014189	MBNL3	95	70.161	Carlito_syrichta
ENSG00000152601	MBNL1	97	80.702	ENSCAPG00000014299	-	89	72.727	Cavia_aperea
ENSG00000152601	MBNL1	97	80.702	ENSCPOG00000010320	MBNL2	99	75.140	Cavia_porcellus
ENSG00000152601	MBNL1	100	99.669	ENSCPOG00000040271	MBNL1	100	99.669	Cavia_porcellus
ENSG00000152601	MBNL1	84	78.846	ENSCPOG00000008092	MBNL3	99	60.165	Cavia_porcellus
ENSG00000152601	MBNL1	76	88.889	ENSCCAG00000033152	MBNL3	96	68.548	Cebus_capucinus
ENSG00000152601	MBNL1	100	100.000	ENSCCAG00000036732	MBNL1	100	100.000	Cebus_capucinus
ENSG00000152601	MBNL1	97	80.702	ENSCCAG00000036167	MBNL2	99	74.054	Cebus_capucinus
ENSG00000152601	MBNL1	93	88.889	ENSCATG00000036303	MBNL3	95	69.758	Cercocebus_atys
ENSG00000152601	MBNL1	100	100.000	ENSCATG00000042844	MBNL1	100	100.000	Cercocebus_atys
ENSG00000152601	MBNL1	97	80.702	ENSCATG00000040406	MBNL2	91	83.621	Cercocebus_atys
ENSG00000152601	MBNL1	84	80.769	ENSCLAG00000001223	MBNL3	99	63.388	Chinchilla_lanigera
ENSG00000152601	MBNL1	97	80.702	ENSCLAG00000003658	MBNL2	99	74.485	Chinchilla_lanigera
ENSG00000152601	MBNL1	100	99.669	ENSCLAG00000002450	MBNL1	100	99.673	Chinchilla_lanigera
ENSG00000152601	MBNL1	100	99.750	ENSCSAG00000011943	MBNL1	100	99.750	Chlorocebus_sabaeus
ENSG00000152601	MBNL1	97	80.702	ENSCSAG00000017523	MBNL2	99	74.054	Chlorocebus_sabaeus
ENSG00000152601	MBNL1	100	65.274	ENSCSAG00000007820	MBNL3	99	64.230	Chlorocebus_sabaeus
ENSG00000152601	MBNL1	97	80.702	ENSCHOG00000000049	MBNL2	89	69.412	Choloepus_hoffmanni
ENSG00000152601	MBNL1	97	80.702	ENSCPBG00000025988	MBNL3	96	68.129	Chrysemys_picta_bellii
ENSG00000152601	MBNL1	97	78.947	ENSCPBG00000023310	MBNL2	97	73.099	Chrysemys_picta_bellii
ENSG00000152601	MBNL1	100	100.000	ENSCPBG00000018808	MBNL1	99	100.000	Chrysemys_picta_bellii
ENSG00000152601	MBNL1	93	88.889	ENSCANG00000040059	MBNL3	95	69.758	Colobus_angolensis_palliatus
ENSG00000152601	MBNL1	97	80.702	ENSCANG00000032119	MBNL2	91	83.621	Colobus_angolensis_palliatus
ENSG00000152601	MBNL1	100	100.000	ENSCANG00000038369	MBNL1	100	100.000	Colobus_angolensis_palliatus
ENSG00000152601	MBNL1	100	99.669	ENSCGRG00001007139	Mbnl1	100	99.669	Cricetulus_griseus_chok1gshd
ENSG00000152601	MBNL1	97	80.702	ENSCGRG00001015686	Mbnl2	99	74.202	Cricetulus_griseus_chok1gshd
ENSG00000152601	MBNL1	96	64.465	ENSCGRG00001006617	Mbnl3	96	67.589	Cricetulus_griseus_chok1gshd
ENSG00000152601	MBNL1	96	64.465	ENSCGRG00000010072	Mbnl3	99	67.589	Cricetulus_griseus_crigri
ENSG00000152601	MBNL1	97	80.702	ENSCGRG00000012163	Mbnl2	99	74.005	Cricetulus_griseus_crigri
ENSG00000152601	MBNL1	100	99.669	ENSCGRG00000004951	Mbnl1	100	99.669	Cricetulus_griseus_crigri
ENSG00000152601	MBNL1	97	92.857	ENSCSEG00000015783	mbnl1	100	79.012	Cynoglossus_semilaevis
ENSG00000152601	MBNL1	95	78.571	ENSCSEG00000003163	-	99	65.722	Cynoglossus_semilaevis
ENSG00000152601	MBNL1	97	77.193	ENSCSEG00000010815	mbnl2	99	70.543	Cynoglossus_semilaevis
ENSG00000152601	MBNL1	97	94.643	ENSCSEG00000008762	MBNL1	100	84.238	Cynoglossus_semilaevis
ENSG00000152601	MBNL1	97	75.000	ENSCSEG00000005665	mbnl3	100	66.106	Cynoglossus_semilaevis
ENSG00000152601	MBNL1	97	94.643	ENSCVAG00000002133	mbnl1	100	74.177	Cyprinodon_variegatus
ENSG00000152601	MBNL1	97	77.193	ENSCVAG00000015236	mbnl2	99	69.867	Cyprinodon_variegatus
ENSG00000152601	MBNL1	97	75.000	ENSCVAG00000014252	mbnl3	100	65.449	Cyprinodon_variegatus
ENSG00000152601	MBNL1	100	93.913	ENSCVAG00000005369	MBNL1	100	84.483	Cyprinodon_variegatus
ENSG00000152601	MBNL1	97	77.193	ENSCVAG00000020926	-	99	71.656	Cyprinodon_variegatus
ENSG00000152601	MBNL1	97	80.702	ENSDARG00000016085	mbnl3	100	67.606	Danio_rerio
ENSG00000152601	MBNL1	97	92.857	ENSDARG00000052978	mbnl1	98	86.957	Danio_rerio
ENSG00000152601	MBNL1	97	77.193	ENSDARG00000018460	mbnl2	100	84.483	Danio_rerio
ENSG00000152601	MBNL1	99	66.307	ENSDNOG00000016518	MBNL3	99	64.960	Dasypus_novemcinctus
ENSG00000152601	MBNL1	100	99.750	ENSDNOG00000044505	MBNL1	100	99.750	Dasypus_novemcinctus
ENSG00000152601	MBNL1	97	80.702	ENSDNOG00000042146	MBNL2	99	75.135	Dasypus_novemcinctus
ENSG00000152601	MBNL1	97	80.702	ENSDORG00000026725	-	80	83.621	Dipodomys_ordii
ENSG00000152601	MBNL1	76	88.889	ENSDORG00000012854	Mbnl3	95	67.742	Dipodomys_ordii
ENSG00000152601	MBNL1	100	99.138	ENSDORG00000029896	Mbnl1	100	99.138	Dipodomys_ordii
ENSG00000152601	MBNL1	97	59.639	ENSETEG00000015907	MBNL3	99	60.165	Echinops_telfairi
ENSG00000152601	MBNL1	97	82.456	ENSETEG00000003784	MBNL2	85	73.457	Echinops_telfairi
ENSG00000152601	MBNL1	86	74.000	ENSEBUG00000016730	-	91	50.746	Eptatretus_burgeri
ENSG00000152601	MBNL1	57	96.970	ENSEBUG00000003843	-	98	54.261	Eptatretus_burgeri
ENSG00000152601	MBNL1	100	99.750	ENSEASG00005020731	MBNL1	100	99.750	Equus_asinus_asinus
ENSG00000152601	MBNL1	96	67.598	ENSEASG00005000227	MBNL3	99	70.968	Equus_asinus_asinus
ENSG00000152601	MBNL1	97	80.702	ENSEASG00005022245	MBNL2	99	74.302	Equus_asinus_asinus
ENSG00000152601	MBNL1	97	80.702	ENSECAG00000020574	MBNL2	84	93.846	Equus_caballus
ENSG00000152601	MBNL1	100	99.750	ENSECAG00000024349	MBNL1	100	99.750	Equus_caballus
ENSG00000152601	MBNL1	99	66.754	ENSECAG00000021076	MBNL3	99	65.375	Equus_caballus
ENSG00000152601	MBNL1	100	99.485	ENSEEUG00000009449	MBNL1	100	99.485	Erinaceus_europaeus
ENSG00000152601	MBNL1	97	80.702	ENSEEUG00000006209	MBNL2	66	76.494	Erinaceus_europaeus
ENSG00000152601	MBNL1	97	75.439	ENSELUG00000020187	-	99	66.752	Esox_lucius
ENSG00000152601	MBNL1	97	78.947	ENSELUG00000003280	mbnl2	99	68.462	Esox_lucius
ENSG00000152601	MBNL1	97	96.429	ENSELUG00000011545	mbnl1	99	74.707	Esox_lucius
ENSG00000152601	MBNL1	97	80.702	ENSELUG00000009313	mbnl3	100	56.479	Esox_lucius
ENSG00000152601	MBNL1	97	96.429	ENSELUG00000010028	MBNL1	100	80.519	Esox_lucius
ENSG00000152601	MBNL1	99	65.445	ENSFCAG00000009604	MBNL3	99	65.385	Felis_catus
ENSG00000152601	MBNL1	97	80.702	ENSFCAG00000028336	MBNL2	99	74.595	Felis_catus
ENSG00000152601	MBNL1	100	100.000	ENSFCAG00000028419	MBNL1	100	100.000	Felis_catus
ENSG00000152601	MBNL1	97	80.702	ENSFALG00000004428	MBNL2	90	78.088	Ficedula_albicollis
ENSG00000152601	MBNL1	100	99.215	ENSFALG00000005088	MBNL1	99	99.215	Ficedula_albicollis
ENSG00000152601	MBNL1	97	80.702	ENSFALG00000001826	MBNL3	100	72.727	Ficedula_albicollis
ENSG00000152601	MBNL1	97	80.702	ENSFDAG00000007399	MBNL2	99	74.485	Fukomys_damarensis
ENSG00000152601	MBNL1	76	88.889	ENSFDAG00000005681	MBNL3	95	67.600	Fukomys_damarensis
ENSG00000152601	MBNL1	100	99.669	ENSFDAG00000012639	MBNL1	100	99.670	Fukomys_damarensis
ENSG00000152601	MBNL1	97	75.000	ENSFHEG00000015097	mbnl3	100	64.607	Fundulus_heteroclitus
ENSG00000152601	MBNL1	97	94.643	ENSFHEG00000017992	mbnl1	99	78.734	Fundulus_heteroclitus
ENSG00000152601	MBNL1	88	80.769	ENSFHEG00000023145	-	97	61.842	Fundulus_heteroclitus
ENSG00000152601	MBNL1	100	95.652	ENSFHEG00000000444	MBNL1	100	85.825	Fundulus_heteroclitus
ENSG00000152601	MBNL1	95	81.197	ENSFHEG00000020400	mbnl2	99	70.633	Fundulus_heteroclitus
ENSG00000152601	MBNL1	95	76.786	ENSGMOG00000002161	mbnl2	99	67.422	Gadus_morhua
ENSG00000152601	MBNL1	97	77.193	ENSGMOG00000003236	-	73	81.897	Gadus_morhua
ENSG00000152601	MBNL1	97	82.456	ENSGMOG00000002820	mbnl3	99	60.870	Gadus_morhua
ENSG00000152601	MBNL1	89	84.483	ENSGMOG00000011845	mbnl1	100	63.077	Gadus_morhua
ENSG00000152601	MBNL1	100	100.000	ENSGALG00000029190	MBNL1	99	100.000	Gallus_gallus
ENSG00000152601	MBNL1	95	83.621	ENSGALG00000016890	MBNL2	99	83.621	Gallus_gallus
ENSG00000152601	MBNL1	100	77.778	ENSGALG00000053597	MBNL3	100	75.556	Gallus_gallus
ENSG00000152601	MBNL1	97	80.702	ENSGAFG00000001972	-	99	64.467	Gambusia_affinis
ENSG00000152601	MBNL1	97	77.193	ENSGAFG00000006045	mbnl2	99	71.576	Gambusia_affinis
ENSG00000152601	MBNL1	100	93.913	ENSGAFG00000013147	MBNL1	100	84.975	Gambusia_affinis
ENSG00000152601	MBNL1	97	94.643	ENSGAFG00000009622	mbnl1	100	78.780	Gambusia_affinis
ENSG00000152601	MBNL1	97	73.214	ENSGAFG00000019836	mbnl3	100	64.045	Gambusia_affinis
ENSG00000152601	MBNL1	97	75.439	ENSGACG00000015105	mbnl2	90	67.683	Gasterosteus_aculeatus
ENSG00000152601	MBNL1	97	96.429	ENSGACG00000010253	MBNL1	100	80.818	Gasterosteus_aculeatus
ENSG00000152601	MBNL1	97	91.071	ENSGACG00000015003	mbnl1	100	77.099	Gasterosteus_aculeatus
ENSG00000152601	MBNL1	95	78.571	ENSGACG00000004222	-	99	63.842	Gasterosteus_aculeatus
ENSG00000152601	MBNL1	97	80.702	ENSGACG00000017015	mbnl3	99	63.188	Gasterosteus_aculeatus
ENSG00000152601	MBNL1	97	80.702	ENSGAGG00000000090	MBNL3	100	72.468	Gopherus_agassizii
ENSG00000152601	MBNL1	97	78.947	ENSGAGG00000014772	MBNL2	99	74.227	Gopherus_agassizii
ENSG00000152601	MBNL1	100	97.419	ENSGAGG00000016381	MBNL1	85	98.148	Gopherus_agassizii
ENSG00000152601	MBNL1	93	88.889	ENSGGOG00000007756	MBNL3	95	68.952	Gorilla_gorilla
ENSG00000152601	MBNL1	100	100.000	ENSGGOG00000009430	MBNL1	100	100.000	Gorilla_gorilla
ENSG00000152601	MBNL1	97	80.702	ENSGGOG00000008349	MBNL2	91	83.621	Gorilla_gorilla
ENSG00000152601	MBNL1	97	77.193	ENSHBUG00000007641	mbnl2	99	71.835	Haplochromis_burtoni
ENSG00000152601	MBNL1	100	95.652	ENSHBUG00000023690	MBNL1	100	85.861	Haplochromis_burtoni
ENSG00000152601	MBNL1	97	94.643	ENSHBUG00000020020	mbnl1	100	80.741	Haplochromis_burtoni
ENSG00000152601	MBNL1	97	78.947	ENSHBUG00000021860	-	99	65.316	Haplochromis_burtoni
ENSG00000152601	MBNL1	97	73.214	ENSHBUG00000013139	mbnl3	100	66.011	Haplochromis_burtoni
ENSG00000152601	MBNL1	76	86.667	ENSHGLG00000006589	MBNL3	99	64.228	Heterocephalus_glaber_female
ENSG00000152601	MBNL1	97	80.702	ENSHGLG00000000575	MBNL2	99	74.485	Heterocephalus_glaber_female
ENSG00000152601	MBNL1	100	99.669	ENSHGLG00000012911	MBNL1	100	99.669	Heterocephalus_glaber_female
ENSG00000152601	MBNL1	100	99.669	ENSHGLG00100017739	MBNL1	100	99.669	Heterocephalus_glaber_male
ENSG00000152601	MBNL1	97	80.702	ENSHGLG00100003403	MBNL2	99	74.485	Heterocephalus_glaber_male
ENSG00000152601	MBNL1	76	86.667	ENSHGLG00100004221	MBNL3	99	63.687	Heterocephalus_glaber_male
ENSG00000152601	MBNL1	97	75.000	ENSHCOG00000003609	mbnl3	99	59.104	Hippocampus_comes
ENSG00000152601	MBNL1	95	78.571	ENSHCOG00000015316	-	98	66.319	Hippocampus_comes
ENSG00000152601	MBNL1	97	89.286	ENSHCOG00000018434	mbnl1	100	74.607	Hippocampus_comes
ENSG00000152601	MBNL1	97	75.439	ENSHCOG00000011265	mbnl2	99	68.908	Hippocampus_comes
ENSG00000152601	MBNL1	97	78.947	ENSIPUG00000021786	mbnl3	96	64.305	Ictalurus_punctatus
ENSG00000152601	MBNL1	97	96.429	ENSIPUG00000003995	MBNL1	100	85.864	Ictalurus_punctatus
ENSG00000152601	MBNL1	93	76.364	ENSIPUG00000018701	mbnl2	99	60.533	Ictalurus_punctatus
ENSG00000152601	MBNL1	97	91.071	ENSIPUG00000009972	mbnl1	100	74.939	Ictalurus_punctatus
ENSG00000152601	MBNL1	93	88.889	ENSSTOG00000006715	MBNL3	95	71.371	Ictidomys_tridecemlineatus
ENSG00000152601	MBNL1	97	80.702	ENSSTOG00000013149	MBNL2	99	74.302	Ictidomys_tridecemlineatus
ENSG00000152601	MBNL1	100	99.669	ENSSTOG00000026711	MBNL1	100	99.669	Ictidomys_tridecemlineatus
ENSG00000152601	MBNL1	97	78.947	ENSJJAG00000018964	Mbnl2	99	74.022	Jaculus_jaculus
ENSG00000152601	MBNL1	93	88.889	ENSJJAG00000004793	Mbnl3	95	70.565	Jaculus_jaculus
ENSG00000152601	MBNL1	100	100.000	ENSJJAG00000022435	Mbnl1	100	100.000	Jaculus_jaculus
ENSG00000152601	MBNL1	97	94.643	ENSKMAG00000020596	mbnl1	100	78.249	Kryptolebias_marmoratus
ENSG00000152601	MBNL1	97	80.702	ENSKMAG00000016876	-	99	67.513	Kryptolebias_marmoratus
ENSG00000152601	MBNL1	100	94.783	ENSKMAG00000019889	MBNL1	100	84.755	Kryptolebias_marmoratus
ENSG00000152601	MBNL1	86	66.423	ENSKMAG00000007888	-	71	65.385	Kryptolebias_marmoratus
ENSG00000152601	MBNL1	97	75.000	ENSKMAG00000003584	mbnl3	100	63.764	Kryptolebias_marmoratus
ENSG00000152601	MBNL1	97	92.857	ENSLBEG00000023101	mbnl1	100	75.663	Labrus_bergylta
ENSG00000152601	MBNL1	97	96.429	ENSLBEG00000023284	MBNL1	100	82.162	Labrus_bergylta
ENSG00000152601	MBNL1	97	82.456	ENSLBEG00000007060	mbnl3	100	63.380	Labrus_bergylta
ENSG00000152601	MBNL1	97	77.193	ENSLBEG00000015200	mbnl2	99	69.081	Labrus_bergylta
ENSG00000152601	MBNL1	97	80.702	ENSLBEG00000018916	-	99	65.051	Labrus_bergylta
ENSG00000152601	MBNL1	97	82.456	ENSLACG00000016501	mbnl2	99	71.899	Latimeria_chalumnae
ENSG00000152601	MBNL1	97	78.947	ENSLACG00000018172	MBNL3	100	71.948	Latimeria_chalumnae
ENSG00000152601	MBNL1	100	92.722	ENSLACG00000013112	MBNL1	100	94.609	Latimeria_chalumnae
ENSG00000152601	MBNL1	97	96.429	ENSLOCG00000002053	mbnl1	100	87.260	Lepisosteus_oculatus
ENSG00000152601	MBNL1	97	77.193	ENSLOCG00000003634	mbnl2	99	72.539	Lepisosteus_oculatus
ENSG00000152601	MBNL1	97	82.456	ENSLOCG00000015065	mbnl3	100	64.976	Lepisosteus_oculatus
ENSG00000152601	MBNL1	100	99.476	ENSLAFG00000017683	MBNL1	99	99.476	Loxodonta_africana
ENSG00000152601	MBNL1	95	66.761	ENSLAFG00000011822	MBNL3	98	65.909	Loxodonta_africana
ENSG00000152601	MBNL1	97	80.702	ENSLAFG00000014497	MBNL2	90	72.414	Loxodonta_africana
ENSG00000152601	MBNL1	85	72.388	ENSMFAG00000041491	MBNL2	99	60.299	Macaca_fascicularis
ENSG00000152601	MBNL1	93	88.889	ENSMFAG00000034599	MBNL3	95	69.758	Macaca_fascicularis
ENSG00000152601	MBNL1	100	100.000	ENSMFAG00000001066	MBNL1	100	100.000	Macaca_fascicularis
ENSG00000152601	MBNL1	85	72.388	ENSMMUG00000022744	MBNL2	99	62.776	Macaca_mulatta
ENSG00000152601	MBNL1	93	88.889	ENSMMUG00000003071	MBNL3	95	69.758	Macaca_mulatta
ENSG00000152601	MBNL1	100	100.000	ENSMMUG00000015910	MBNL1	100	100.000	Macaca_mulatta
ENSG00000152601	MBNL1	79	87.234	ENSMNEG00000039160	MBNL3	99	64.136	Macaca_nemestrina
ENSG00000152601	MBNL1	97	80.702	ENSMNEG00000044636	MBNL2	91	83.621	Macaca_nemestrina
ENSG00000152601	MBNL1	100	100.000	ENSMNEG00000031295	MBNL1	100	100.000	Macaca_nemestrina
ENSG00000152601	MBNL1	100	100.000	ENSMLEG00000041395	MBNL1	100	100.000	Mandrillus_leucophaeus
ENSG00000152601	MBNL1	97	80.702	ENSMLEG00000030404	MBNL2	91	83.621	Mandrillus_leucophaeus
ENSG00000152601	MBNL1	93	88.889	ENSMLEG00000028867	MBNL3	95	70.161	Mandrillus_leucophaeus
ENSG00000152601	MBNL1	97	96.429	ENSMAMG00000012935	MBNL1	100	95.652	Mastacembelus_armatus
ENSG00000152601	MBNL1	97	75.439	ENSMAMG00000022173	mbnl2	99	70.868	Mastacembelus_armatus
ENSG00000152601	MBNL1	97	78.947	ENSMAMG00000012429	-	98	64.885	Mastacembelus_armatus
ENSG00000152601	MBNL1	97	92.857	ENSMAMG00000011321	mbnl1	99	87.826	Mastacembelus_armatus
ENSG00000152601	MBNL1	97	75.000	ENSMAMG00000021465	mbnl3	100	65.449	Mastacembelus_armatus
ENSG00000152601	MBNL1	100	95.652	ENSMZEG00005001198	MBNL1	100	85.861	Maylandia_zebra
ENSG00000152601	MBNL1	97	94.643	ENSMZEG00005020050	mbnl1	100	80.741	Maylandia_zebra
ENSG00000152601	MBNL1	97	77.193	ENSMZEG00005005609	mbnl2	99	68.627	Maylandia_zebra
ENSG00000152601	MBNL1	97	73.214	ENSMZEG00005005200	mbnl3	100	66.011	Maylandia_zebra
ENSG00000152601	MBNL1	97	78.947	ENSMZEG00005003492	-	99	66.414	Maylandia_zebra
ENSG00000152601	MBNL1	97	100.000	ENSMGAG00000010862	MBNL1	100	98.034	Meleagris_gallopavo
ENSG00000152601	MBNL1	95	83.621	ENSMGAG00000014904	MBNL2	99	83.621	Meleagris_gallopavo
ENSG00000152601	MBNL1	100	77.778	ENSMGAG00000003064	MBNL3	100	75.556	Meleagris_gallopavo
ENSG00000152601	MBNL1	100	99.669	ENSMAUG00000004011	Mbnl1	100	99.669	Mesocricetus_auratus
ENSG00000152601	MBNL1	97	80.702	ENSMAUG00000013854	Mbnl2	99	71.562	Mesocricetus_auratus
ENSG00000152601	MBNL1	96	64.780	ENSMAUG00000000984	Mbnl3	99	67.589	Mesocricetus_auratus
ENSG00000152601	MBNL1	100	100.000	ENSMICG00000049530	MBNL1	100	100.000	Microcebus_murinus
ENSG00000152601	MBNL1	95	83.621	ENSMICG00000038018	MBNL2	99	74.324	Microcebus_murinus
ENSG00000152601	MBNL1	93	88.889	ENSMICG00000032488	MBNL3	99	66.216	Microcebus_murinus
ENSG00000152601	MBNL1	97	80.702	ENSMOCG00000000755	Mbnl2	99	73.743	Microtus_ochrogaster
ENSG00000152601	MBNL1	96	64.804	ENSMOCG00000011470	Mbnl3	99	66.667	Microtus_ochrogaster
ENSG00000152601	MBNL1	100	100.000	ENSMOCG00000016746	Mbnl1	100	100.000	Microtus_ochrogaster
ENSG00000152601	MBNL1	97	75.000	ENSMMOG00000002757	mbnl3	98	64.426	Mola_mola
ENSG00000152601	MBNL1	100	92.174	ENSMMOG00000012829	MBNL1	100	84.533	Mola_mola
ENSG00000152601	MBNL1	98	90.826	ENSMMOG00000019020	mbnl1	100	74.272	Mola_mola
ENSG00000152601	MBNL1	97	82.456	ENSMMOG00000020119	-	88	75.556	Mola_mola
ENSG00000152601	MBNL1	97	75.439	ENSMMOG00000006563	mbnl2	99	68.524	Mola_mola
ENSG00000152601	MBNL1	100	98.500	ENSMODG00000015838	MBNL1	100	98.500	Monodelphis_domestica
ENSG00000152601	MBNL1	97	80.702	ENSMODG00000008566	MBNL2	99	75.266	Monodelphis_domestica
ENSG00000152601	MBNL1	97	80.702	ENSMODG00000015304	MBNL3	99	73.569	Monodelphis_domestica
ENSG00000152601	MBNL1	97	77.193	ENSMALG00000011573	mbnl2	99	69.786	Monopterus_albus
ENSG00000152601	MBNL1	97	78.947	ENSMALG00000011038	-	99	65.147	Monopterus_albus
ENSG00000152601	MBNL1	97	96.429	ENSMALG00000010192	MBNL1	100	85.926	Monopterus_albus
ENSG00000152601	MBNL1	97	92.857	ENSMALG00000015245	mbnl1	99	87.826	Monopterus_albus
ENSG00000152601	MBNL1	97	75.000	ENSMALG00000011399	mbnl3	95	65.826	Monopterus_albus
ENSG00000152601	MBNL1	96	62.893	MGP_CAROLIEiJ_G0033061	Mbnl3	99	61.345	Mus_caroli
ENSG00000152601	MBNL1	97	80.702	MGP_CAROLIEiJ_G0019601	Mbnl2	99	74.485	Mus_caroli
ENSG00000152601	MBNL1	100	100.000	MGP_CAROLIEiJ_G0025027	Mbnl1	100	100.000	Mus_caroli
ENSG00000152601	MBNL1	96	63.208	ENSMUSG00000036109	Mbnl3	97	66.667	Mus_musculus
ENSG00000152601	MBNL1	100	100.000	ENSMUSG00000027763	Mbnl1	100	100.000	Mus_musculus
ENSG00000152601	MBNL1	97	80.702	ENSMUSG00000022139	Mbnl2	99	74.485	Mus_musculus
ENSG00000152601	MBNL1	100	99.669	MGP_PahariEiJ_G0026471	Mbnl1	100	99.669	Mus_pahari
ENSG00000152601	MBNL1	97	80.702	MGP_PahariEiJ_G0030618	Mbnl2	99	74.227	Mus_pahari
ENSG00000152601	MBNL1	96	62.264	MGP_PahariEiJ_G0031606	Mbnl3	95	65.079	Mus_pahari
ENSG00000152601	MBNL1	100	100.000	MGP_SPRETEiJ_G0025967	Mbnl1	100	100.000	Mus_spretus
ENSG00000152601	MBNL1	97	80.702	MGP_SPRETEiJ_G0020498	Mbnl2	99	74.485	Mus_spretus
ENSG00000152601	MBNL1	96	63.208	MGP_SPRETEiJ_G0034219	Mbnl3	97	66.667	Mus_spretus
ENSG00000152601	MBNL1	100	100.000	ENSMPUG00000002708	MBNL1	100	90.931	Mustela_putorius_furo
ENSG00000152601	MBNL1	99	65.445	ENSMPUG00000002178	MBNL3	99	64.398	Mustela_putorius_furo
ENSG00000152601	MBNL1	97	80.702	ENSMPUG00000011750	MBNL2	89	72.256	Mustela_putorius_furo
ENSG00000152601	MBNL1	76	86.667	ENSMLUG00000016240	MBNL3	99	64.033	Myotis_lucifugus
ENSG00000152601	MBNL1	100	98.889	ENSMLUG00000014029	-	100	99.123	Myotis_lucifugus
ENSG00000152601	MBNL1	97	80.702	ENSMLUG00000010920	MBNL2	98	73.037	Myotis_lucifugus
ENSG00000152601	MBNL1	99	62.658	ENSNGAG00000019720	Mbnl3	95	69.444	Nannospalax_galili
ENSG00000152601	MBNL1	100	100.000	ENSNGAG00000021701	Mbnl1	100	100.000	Nannospalax_galili
ENSG00000152601	MBNL1	97	80.702	ENSNGAG00000008645	Mbnl2	99	74.202	Nannospalax_galili
ENSG00000152601	MBNL1	97	80.702	ENSNBRG00000009899	-	99	65.823	Neolamprologus_brichardi
ENSG00000152601	MBNL1	100	95.652	ENSNBRG00000002469	MBNL1	100	85.861	Neolamprologus_brichardi
ENSG00000152601	MBNL1	97	73.214	ENSNBRG00000000383	mbnl3	99	65.922	Neolamprologus_brichardi
ENSG00000152601	MBNL1	97	77.193	ENSNBRG00000008611	mbnl2	99	71.989	Neolamprologus_brichardi
ENSG00000152601	MBNL1	97	94.643	ENSNBRG00000017341	mbnl1	100	80.407	Neolamprologus_brichardi
ENSG00000152601	MBNL1	97	80.702	ENSNLEG00000007827	MBNL2	91	83.621	Nomascus_leucogenys
ENSG00000152601	MBNL1	93	88.889	ENSNLEG00000001722	MBNL3	95	69.355	Nomascus_leucogenys
ENSG00000152601	MBNL1	100	100.000	ENSNLEG00000003537	MBNL1	100	100.000	Nomascus_leucogenys
ENSG00000152601	MBNL1	97	80.702	ENSMEUG00000001183	MBNL3	99	74.114	Notamacropus_eugenii
ENSG00000152601	MBNL1	97	80.702	ENSMEUG00000016143	MBNL2	77	92.308	Notamacropus_eugenii
ENSG00000152601	MBNL1	97	82.456	ENSOPRG00000007427	MBNL2	90	70.468	Ochotona_princeps
ENSG00000152601	MBNL1	100	100.000	ENSOPRG00000009633	MBNL1	87	100.000	Ochotona_princeps
ENSG00000152601	MBNL1	100	99.669	ENSODEG00000002786	MBNL1	100	99.670	Octodon_degus
ENSG00000152601	MBNL1	97	80.702	ENSODEG00000011921	MBNL2	99	73.936	Octodon_degus
ENSG00000152601	MBNL1	76	86.667	ENSODEG00000011309	MBNL3	99	63.305	Octodon_degus
ENSG00000152601	MBNL1	100	95.652	ENSONIG00000003561	MBNL1	100	85.411	Oreochromis_niloticus
ENSG00000152601	MBNL1	97	77.193	ENSONIG00000012173	mbnl2	99	72.087	Oreochromis_niloticus
ENSG00000152601	MBNL1	97	94.643	ENSONIG00000010043	mbnl1	100	78.030	Oreochromis_niloticus
ENSG00000152601	MBNL1	97	73.214	ENSONIG00000005428	mbnl3	100	66.011	Oreochromis_niloticus
ENSG00000152601	MBNL1	97	80.702	ENSOANG00000014911	MBNL2	99	73.969	Ornithorhynchus_anatinus
ENSG00000152601	MBNL1	97	80.702	ENSOANG00000011697	MBNL3	100	72.208	Ornithorhynchus_anatinus
ENSG00000152601	MBNL1	100	98.065	ENSOANG00000007992	MBNL1	95	82.036	Ornithorhynchus_anatinus
ENSG00000152601	MBNL1	100	99.750	ENSOCUG00000007601	MBNL1	100	99.750	Oryctolagus_cuniculus
ENSG00000152601	MBNL1	97	82.456	ENSOCUG00000000220	MBNL2	99	74.742	Oryctolagus_cuniculus
ENSG00000152601	MBNL1	88	81.481	ENSOCUG00000014979	MBNL3	99	62.304	Oryctolagus_cuniculus
ENSG00000152601	MBNL1	93	96.296	ENSORLG00000030507	mbnl1	100	80.255	Oryzias_latipes
ENSG00000152601	MBNL1	86	79.245	ENSORLG00000002183	mbnl3	100	60.563	Oryzias_latipes
ENSG00000152601	MBNL1	95	76.786	ENSORLG00000005419	mbnl2	99	70.588	Oryzias_latipes
ENSG00000152601	MBNL1	100	93.913	ENSORLG00000005925	MBNL1	100	85.679	Oryzias_latipes
ENSG00000152601	MBNL1	97	80.702	ENSORLG00000022713	-	99	65.990	Oryzias_latipes
ENSG00000152601	MBNL1	97	92.857	ENSORLG00020004441	MBNL1	89	90.514	Oryzias_latipes_hni
ENSG00000152601	MBNL1	97	80.702	ENSORLG00020000914	-	99	65.736	Oryzias_latipes_hni
ENSG00000152601	MBNL1	95	76.786	ENSORLG00020016031	mbnl2	99	70.543	Oryzias_latipes_hni
ENSG00000152601	MBNL1	93	96.296	ENSORLG00020015303	mbnl1	100	80.573	Oryzias_latipes_hni
ENSG00000152601	MBNL1	86	79.245	ENSORLG00020019753	mbnl3	100	60.282	Oryzias_latipes_hni
ENSG00000152601	MBNL1	97	80.702	ENSORLG00015012808	-	93	79.310	Oryzias_latipes_hsok
ENSG00000152601	MBNL1	100	93.913	ENSORLG00015000195	MBNL1	100	86.173	Oryzias_latipes_hsok
ENSG00000152601	MBNL1	93	96.296	ENSORLG00015015256	mbnl1	100	80.255	Oryzias_latipes_hsok
ENSG00000152601	MBNL1	95	76.786	ENSORLG00015014422	mbnl2	99	70.588	Oryzias_latipes_hsok
ENSG00000152601	MBNL1	86	79.245	ENSORLG00015016520	mbnl3	100	60.282	Oryzias_latipes_hsok
ENSG00000152601	MBNL1	93	96.296	ENSOMEG00000022944	mbnl1	100	78.624	Oryzias_melastigma
ENSG00000152601	MBNL1	97	77.193	ENSOMEG00000007821	mbnl2	99	71.318	Oryzias_melastigma
ENSG00000152601	MBNL1	86	79.245	ENSOMEG00000018072	mbnl3	100	60.282	Oryzias_melastigma
ENSG00000152601	MBNL1	97	92.857	ENSOMEG00000011262	MBNL1	100	85.749	Oryzias_melastigma
ENSG00000152601	MBNL1	86	81.132	ENSOGAG00000003143	MBNL3	97	64.208	Otolemur_garnettii
ENSG00000152601	MBNL1	100	99.355	ENSOGAG00000032201	MBNL1	100	97.812	Otolemur_garnettii
ENSG00000152601	MBNL1	97	80.702	ENSOGAG00000017001	MBNL2	88	72.840	Otolemur_garnettii
ENSG00000152601	MBNL1	100	99.750	ENSOARG00000003701	MBNL1	100	99.750	Ovis_aries
ENSG00000152601	MBNL1	97	80.702	ENSOARG00000002685	MBNL2	99	66.755	Ovis_aries
ENSG00000152601	MBNL1	88	79.630	ENSOARG00000012405	MBNL3	99	62.097	Ovis_aries
ENSG00000152601	MBNL1	97	80.702	ENSPPAG00000035995	MBNL2	91	83.621	Pan_paniscus
ENSG00000152601	MBNL1	100	100.000	ENSPPAG00000031243	MBNL1	100	100.000	Pan_paniscus
ENSG00000152601	MBNL1	76	88.889	ENSPPAG00000034764	MBNL3	99	64.384	Pan_paniscus
ENSG00000152601	MBNL1	76	86.667	ENSPPRG00000012374	MBNL3	95	69.355	Panthera_pardus
ENSG00000152601	MBNL1	100	100.000	ENSPPRG00000005721	MBNL1	100	100.000	Panthera_pardus
ENSG00000152601	MBNL1	97	80.702	ENSPPRG00000022785	MBNL2	99	74.595	Panthera_pardus
ENSG00000152601	MBNL1	100	100.000	ENSPTIG00000022119	MBNL1	100	100.000	Panthera_tigris_altaica
ENSG00000152601	MBNL1	76	86.667	ENSPTIG00000016618	MBNL3	99	64.286	Panthera_tigris_altaica
ENSG00000152601	MBNL1	97	80.702	ENSPTIG00000003558	MBNL2	99	72.703	Panthera_tigris_altaica
ENSG00000152601	MBNL1	76	88.889	ENSPTRG00000022280	MBNL3	99	64.589	Pan_troglodytes
ENSG00000152601	MBNL1	97	80.702	ENSPTRG00000005982	MBNL2	99	79.866	Pan_troglodytes
ENSG00000152601	MBNL1	100	100.000	ENSPTRG00000015542	MBNL1	100	100.000	Pan_troglodytes
ENSG00000152601	MBNL1	76	88.889	ENSPANG00000011360	MBNL3	99	64.932	Papio_anubis
ENSG00000152601	MBNL1	97	80.702	ENSPANG00000007199	MBNL2	91	83.621	Papio_anubis
ENSG00000152601	MBNL1	100	93.043	ENSPKIG00000010173	mbnl1	100	86.534	Paramormyrops_kingsleyae
ENSG00000152601	MBNL1	97	77.193	ENSPKIG00000005813	mbnl2	99	69.689	Paramormyrops_kingsleyae
ENSG00000152601	MBNL1	97	77.193	ENSPKIG00000021063	mbnl3	99	60.000	Paramormyrops_kingsleyae
ENSG00000152601	MBNL1	97	73.684	ENSPKIG00000010987	-	99	67.876	Paramormyrops_kingsleyae
ENSG00000152601	MBNL1	97	78.947	ENSPSIG00000017802	MBNL2	99	73.670	Pelodiscus_sinensis
ENSG00000152601	MBNL1	100	100.000	ENSPSIG00000008090	MBNL1	98	100.000	Pelodiscus_sinensis
ENSG00000152601	MBNL1	97	80.702	ENSPSIG00000017914	MBNL3	100	74.690	Pelodiscus_sinensis
ENSG00000152601	MBNL1	97	77.193	ENSPMGG00000011891	-	99	63.966	Periophthalmus_magnuspinnatus
ENSG00000152601	MBNL1	97	94.643	ENSPMGG00000014902	mbnl1	100	82.803	Periophthalmus_magnuspinnatus
ENSG00000152601	MBNL1	100	95.652	ENSPMGG00000013974	MBNL1	100	86.133	Periophthalmus_magnuspinnatus
ENSG00000152601	MBNL1	98	72.414	ENSPMGG00000009303	-	92	60.194	Periophthalmus_magnuspinnatus
ENSG00000152601	MBNL1	96	60.188	ENSPMGG00000017449	mbnl3	99	59.890	Periophthalmus_magnuspinnatus
ENSG00000152601	MBNL1	76	86.667	ENSPEMG00000024156	Mbnl3	95	67.984	Peromyscus_maniculatus_bairdii
ENSG00000152601	MBNL1	100	100.000	ENSPEMG00000011590	Mbnl1	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000152601	MBNL1	97	75.439	ENSPMAG00000005739	mbnl1	100	59.327	Petromyzon_marinus
ENSG00000152601	MBNL1	100	97.989	ENSPCIG00000019478	MBNL1	100	97.989	Phascolarctos_cinereus
ENSG00000152601	MBNL1	96	68.627	ENSPCIG00000014292	MBNL3	98	68.235	Phascolarctos_cinereus
ENSG00000152601	MBNL1	97	80.702	ENSPCIG00000027630	MBNL2	99	75.000	Phascolarctos_cinereus
ENSG00000152601	MBNL1	97	94.643	ENSPFOG00000023501	mbnl1	100	78.125	Poecilia_formosa
ENSG00000152601	MBNL1	97	75.000	ENSPFOG00000008576	mbnl3	100	64.888	Poecilia_formosa
ENSG00000152601	MBNL1	97	80.702	ENSPFOG00000008432	-	89	81.034	Poecilia_formosa
ENSG00000152601	MBNL1	97	77.193	ENSPFOG00000002871	mbnl2	99	68.533	Poecilia_formosa
ENSG00000152601	MBNL1	100	95.652	ENSPFOG00000009951	MBNL1	100	85.530	Poecilia_formosa
ENSG00000152601	MBNL1	97	82.456	ENSPLAG00000009523	mbnl3	100	64.888	Poecilia_latipinna
ENSG00000152601	MBNL1	97	77.193	ENSPLAG00000004705	mbnl2	99	69.638	Poecilia_latipinna
ENSG00000152601	MBNL1	97	80.702	ENSPLAG00000021820	-	95	68.063	Poecilia_latipinna
ENSG00000152601	MBNL1	100	95.652	ENSPLAG00000020272	MBNL1	100	85.090	Poecilia_latipinna
ENSG00000152601	MBNL1	97	94.643	ENSPLAG00000019686	mbnl1	99	76.099	Poecilia_latipinna
ENSG00000152601	MBNL1	97	94.643	ENSPMEG00000011573	-	81	93.846	Poecilia_mexicana
ENSG00000152601	MBNL1	97	75.000	ENSPMEG00000009501	mbnl3	100	64.607	Poecilia_mexicana
ENSG00000152601	MBNL1	100	95.652	ENSPMEG00000004233	MBNL1	100	85.052	Poecilia_mexicana
ENSG00000152601	MBNL1	97	77.193	ENSPMEG00000009993	mbnl2	88	87.692	Poecilia_mexicana
ENSG00000152601	MBNL1	97	80.702	ENSPMEG00000001093	-	99	64.975	Poecilia_mexicana
ENSG00000152601	MBNL1	97	77.193	ENSPREG00000009937	-	99	70.571	Poecilia_reticulata
ENSG00000152601	MBNL1	97	80.702	ENSPREG00000002740	-	99	64.975	Poecilia_reticulata
ENSG00000152601	MBNL1	97	94.643	ENSPREG00000016751	mbnl1	100	79.361	Poecilia_reticulata
ENSG00000152601	MBNL1	89	94.828	ENSPREG00000002629	MBNL1	100	73.039	Poecilia_reticulata
ENSG00000152601	MBNL1	97	75.000	ENSPREG00000008529	mbnl3	95	65.266	Poecilia_reticulata
ENSG00000152601	MBNL1	97	80.702	ENSPPYG00000005456	MBNL2	99	73.969	Pongo_abelii
ENSG00000152601	MBNL1	100	99.738	ENSPPYG00000014218	MBNL1	100	99.738	Pongo_abelii
ENSG00000152601	MBNL1	76	88.889	ENSPPYG00000020726	MBNL3	99	64.384	Pongo_abelii
ENSG00000152601	MBNL1	84	78.846	ENSPCAG00000014188	MBNL3	99	59.677	Procavia_capensis
ENSG00000152601	MBNL1	100	98.710	ENSPCAG00000002143	MBNL1	100	99.394	Procavia_capensis
ENSG00000152601	MBNL1	97	80.702	ENSPCAG00000005151	MBNL2	100	73.294	Procavia_capensis
ENSG00000152601	MBNL1	100	100.000	ENSPCOG00000023511	MBNL1	100	99.706	Propithecus_coquereli
ENSG00000152601	MBNL1	97	80.702	ENSPCOG00000020365	MBNL2	99	74.324	Propithecus_coquereli
ENSG00000152601	MBNL1	76	88.889	ENSPCOG00000025398	MBNL3	95	69.960	Propithecus_coquereli
ENSG00000152601	MBNL1	97	80.702	ENSPVAG00000003263	MBNL2	89	73.077	Pteropus_vampyrus
ENSG00000152601	MBNL1	84	82.692	ENSPVAG00000006115	MBNL3	99	61.918	Pteropus_vampyrus
ENSG00000152601	MBNL1	100	99.485	ENSPVAG00000002760	MBNL1	100	99.485	Pteropus_vampyrus
ENSG00000152601	MBNL1	97	94.643	ENSPNYG00000009278	mbnl1	100	80.153	Pundamilia_nyererei
ENSG00000152601	MBNL1	97	77.193	ENSPNYG00000016734	mbnl2	99	68.627	Pundamilia_nyererei
ENSG00000152601	MBNL1	97	80.702	ENSPNYG00000010558	-	99	65.570	Pundamilia_nyererei
ENSG00000152601	MBNL1	97	73.214	ENSPNYG00000014072	mbnl3	100	66.011	Pundamilia_nyererei
ENSG00000152601	MBNL1	100	95.652	ENSPNYG00000007535	MBNL1	100	85.411	Pundamilia_nyererei
ENSG00000152601	MBNL1	97	80.702	ENSPNAG00000007910	mbnl3	99	61.224	Pygocentrus_nattereri
ENSG00000152601	MBNL1	93	76.364	ENSPNAG00000022728	-	99	60.567	Pygocentrus_nattereri
ENSG00000152601	MBNL1	97	94.643	ENSPNAG00000021243	mbnl1	98	89.565	Pygocentrus_nattereri
ENSG00000152601	MBNL1	100	95.652	ENSPNAG00000005711	MBNL1	100	87.593	Pygocentrus_nattereri
ENSG00000152601	MBNL1	100	99.742	ENSRNOG00000014076	Mbnl1	100	99.742	Rattus_norvegicus
ENSG00000152601	MBNL1	97	80.702	ENSRNOG00000010737	Mbnl2	99	74.202	Rattus_norvegicus
ENSG00000152601	MBNL1	76	86.667	ENSRNOG00000002487	Mbnl3	99	62.185	Rattus_norvegicus
ENSG00000152601	MBNL1	97	80.702	ENSRBIG00000032413	MBNL2	91	83.621	Rhinopithecus_bieti
ENSG00000152601	MBNL1	93	88.889	ENSRBIG00000028181	MBNL3	95	69.758	Rhinopithecus_bieti
ENSG00000152601	MBNL1	100	100.000	ENSRBIG00000030443	MBNL1	100	100.000	Rhinopithecus_bieti
ENSG00000152601	MBNL1	100	100.000	ENSRROG00000000867	MBNL1	100	100.000	Rhinopithecus_roxellana
ENSG00000152601	MBNL1	93	88.889	ENSRROG00000040613	MBNL3	95	70.161	Rhinopithecus_roxellana
ENSG00000152601	MBNL1	97	80.702	ENSRROG00000045272	MBNL2	91	83.621	Rhinopithecus_roxellana
ENSG00000152601	MBNL1	97	80.702	ENSSBOG00000020646	MBNL2	92	83.621	Saimiri_boliviensis_boliviensis
ENSG00000152601	MBNL1	100	100.000	ENSSBOG00000020980	MBNL1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000152601	MBNL1	76	88.889	ENSSBOG00000026045	MBNL3	96	68.145	Saimiri_boliviensis_boliviensis
ENSG00000152601	MBNL1	97	80.702	ENSSHAG00000010745	MBNL2	91	75.070	Sarcophilus_harrisii
ENSG00000152601	MBNL1	97	80.702	ENSSHAG00000014058	MBNL3	99	73.641	Sarcophilus_harrisii
ENSG00000152601	MBNL1	100	98.429	ENSSHAG00000018364	MBNL1	100	98.429	Sarcophilus_harrisii
ENSG00000152601	MBNL1	97	75.439	ENSSFOG00015006106	-	99	70.026	Scleropages_formosus
ENSG00000152601	MBNL1	97	78.947	ENSSFOG00015008968	mbnl3	99	61.560	Scleropages_formosus
ENSG00000152601	MBNL1	97	77.193	ENSSFOG00015003664	-	99	69.101	Scleropages_formosus
ENSG00000152601	MBNL1	97	80.702	ENSSFOG00015012501	mbnl3	100	67.416	Scleropages_formosus
ENSG00000152601	MBNL1	100	93.043	ENSSFOG00015019438	mbnl1	100	84.694	Scleropages_formosus
ENSG00000152601	MBNL1	97	77.193	ENSSMAG00000006063	mbnl2	99	70.026	Scophthalmus_maximus
ENSG00000152601	MBNL1	97	96.429	ENSSMAG00000012127	MBNL1	100	84.156	Scophthalmus_maximus
ENSG00000152601	MBNL1	97	73.214	ENSSMAG00000017087	mbnl3	99	65.363	Scophthalmus_maximus
ENSG00000152601	MBNL1	97	94.643	ENSSMAG00000000990	mbnl1	100	78.624	Scophthalmus_maximus
ENSG00000152601	MBNL1	97	78.947	ENSSMAG00000016268	-	99	65.553	Scophthalmus_maximus
ENSG00000152601	MBNL1	97	77.193	ENSSDUG00000021551	mbnl2	99	72.093	Seriola_dumerili
ENSG00000152601	MBNL1	97	78.947	ENSSDUG00000002243	-	97	65.990	Seriola_dumerili
ENSG00000152601	MBNL1	97	73.214	ENSSDUG00000017970	mbnl3	100	61.519	Seriola_dumerili
ENSG00000152601	MBNL1	100	95.652	ENSSDUG00000014314	MBNL1	100	87.160	Seriola_dumerili
ENSG00000152601	MBNL1	97	94.643	ENSSDUG00000017900	mbnl1	99	88.696	Seriola_dumerili
ENSG00000152601	MBNL1	97	77.193	ENSSLDG00000002279	-	99	66.758	Seriola_lalandi_dorsalis
ENSG00000152601	MBNL1	97	73.214	ENSSLDG00000016857	mbnl3	94	63.686	Seriola_lalandi_dorsalis
ENSG00000152601	MBNL1	97	94.643	ENSSLDG00000014449	mbnl1	99	88.696	Seriola_lalandi_dorsalis
ENSG00000152601	MBNL1	97	77.193	ENSSLDG00000013155	mbnl2	99	71.709	Seriola_lalandi_dorsalis
ENSG00000152601	MBNL1	100	95.652	ENSSLDG00000015286	MBNL1	100	86.822	Seriola_lalandi_dorsalis
ENSG00000152601	MBNL1	76	86.667	ENSSARG00000006397	MBNL3	99	64.402	Sorex_araneus
ENSG00000152601	MBNL1	97	80.702	ENSSARG00000002868	MBNL2	85	72.840	Sorex_araneus
ENSG00000152601	MBNL1	97	82.456	ENSSPUG00000000301	MBNL3	100	72.922	Sphenodon_punctatus
ENSG00000152601	MBNL1	97	80.702	ENSSPUG00000010673	MBNL2	90	77.291	Sphenodon_punctatus
ENSG00000152601	MBNL1	100	97.487	ENSSPUG00000004047	MBNL1	100	82.483	Sphenodon_punctatus
ENSG00000152601	MBNL1	97	94.643	ENSSPAG00000015059	mbnl1	100	80.344	Stegastes_partitus
ENSG00000152601	MBNL1	97	77.193	ENSSPAG00000012815	mbnl2	99	69.867	Stegastes_partitus
ENSG00000152601	MBNL1	100	95.652	ENSSPAG00000002812	MBNL1	100	86.914	Stegastes_partitus
ENSG00000152601	MBNL1	97	75.000	ENSSPAG00000006933	mbnl3	100	65.449	Stegastes_partitus
ENSG00000152601	MBNL1	97	80.702	ENSSPAG00000006349	-	99	67.259	Stegastes_partitus
ENSG00000152601	MBNL1	86	83.019	ENSSSCG00000012676	MBNL3	99	65.969	Sus_scrofa
ENSG00000152601	MBNL1	100	100.000	ENSSSCG00000011720	MBNL1	100	99.750	Sus_scrofa
ENSG00000152601	MBNL1	97	78.947	ENSSSCG00000009505	MBNL2	89	93.846	Sus_scrofa
ENSG00000152601	MBNL1	97	80.702	ENSTGUG00000011104	MBNL2	90	78.088	Taeniopygia_guttata
ENSG00000152601	MBNL1	100	98.168	ENSTGUG00000011341	MBNL1	99	98.168	Taeniopygia_guttata
ENSG00000152601	MBNL1	97	80.702	ENSTGUG00000002999	MBNL3	100	72.727	Taeniopygia_guttata
ENSG00000152601	MBNL1	97	75.000	ENSTRUG00000012666	mbnl3	100	64.607	Takifugu_rubripes
ENSG00000152601	MBNL1	97	91.071	ENSTRUG00000013858	mbnl1	100	78.149	Takifugu_rubripes
ENSG00000152601	MBNL1	95	75.000	ENSTRUG00000010220	mbnl2a	99	68.800	Takifugu_rubripes
ENSG00000152601	MBNL1	100	93.913	ENSTRUG00000022652	MBNL1	100	79.500	Takifugu_rubripes
ENSG00000152601	MBNL1	97	77.193	ENSTRUG00000017351	-	87	62.037	Takifugu_rubripes
ENSG00000152601	MBNL1	97	94.643	ENSTNIG00000007695	MBNL1	100	81.322	Tetraodon_nigroviridis
ENSG00000152601	MBNL1	97	91.071	ENSTNIG00000003878	mbnl1	90	93.846	Tetraodon_nigroviridis
ENSG00000152601	MBNL1	97	75.000	ENSTNIG00000016812	mbnl3	99	64.865	Tetraodon_nigroviridis
ENSG00000152601	MBNL1	97	75.439	ENSTNIG00000014533	-	90	80.172	Tetraodon_nigroviridis
ENSG00000152601	MBNL1	97	80.702	ENSTBEG00000005178	MBNL2	77	93.846	Tupaia_belangeri
ENSG00000152601	MBNL1	100	99.742	ENSTTRG00000009991	MBNL1	100	99.742	Tursiops_truncatus
ENSG00000152601	MBNL1	97	80.702	ENSTTRG00000008491	MBNL2	86	78.088	Tursiops_truncatus
ENSG00000152601	MBNL1	100	99.355	ENSUAMG00000018732	MBNL1	100	99.692	Ursus_americanus
ENSG00000152601	MBNL1	97	80.702	ENSUAMG00000008558	MBNL2	99	73.969	Ursus_americanus
ENSG00000152601	MBNL1	95	67.989	ENSUAMG00000011410	MBNL3	95	70.565	Ursus_americanus
ENSG00000152601	MBNL1	76	86.667	ENSUMAG00000012026	MBNL3	99	59.459	Ursus_maritimus
ENSG00000152601	MBNL1	97	80.702	ENSUMAG00000025199	MBNL2	95	83.621	Ursus_maritimus
ENSG00000152601	MBNL1	100	99.750	ENSUMAG00000012004	MBNL1	100	99.750	Ursus_maritimus
ENSG00000152601	MBNL1	97	80.702	ENSVPAG00000010696	MBNL2	86	78.088	Vicugna_pacos
ENSG00000152601	MBNL1	97	66.566	ENSVPAG00000004743	MBNL3	99	67.123	Vicugna_pacos
ENSG00000152601	MBNL1	100	99.355	ENSVPAG00000006162	MBNL1	100	99.742	Vicugna_pacos
ENSG00000152601	MBNL1	97	80.702	ENSVVUG00000006871	MBNL2	99	74.227	Vulpes_vulpes
ENSG00000152601	MBNL1	99	65.969	ENSVVUG00000013862	MBNL3	99	66.027	Vulpes_vulpes
ENSG00000152601	MBNL1	100	99.750	ENSVVUG00000010763	MBNL1	100	99.750	Vulpes_vulpes
ENSG00000152601	MBNL1	97	80.702	ENSXETG00000033349	mbnl2	99	75.000	Xenopus_tropicalis
ENSG00000152601	MBNL1	97	80.702	ENSXETG00000005409	mbnl3	97	72.944	Xenopus_tropicalis
ENSG00000152601	MBNL1	100	90.323	ENSXETG00000021655	mbnl1	100	91.228	Xenopus_tropicalis
ENSG00000152601	MBNL1	88	72.549	ENSXCOG00000015641	mbnl3	93	57.273	Xiphophorus_couchianus
ENSG00000152601	MBNL1	97	94.643	ENSXCOG00000001879	mbnl1	100	79.045	Xiphophorus_couchianus
ENSG00000152601	MBNL1	97	80.702	ENSXCOG00000019080	-	99	64.894	Xiphophorus_couchianus
ENSG00000152601	MBNL1	97	77.193	ENSXCOG00000020237	mbnl2	99	71.148	Xiphophorus_couchianus
ENSG00000152601	MBNL1	100	94.783	ENSXCOG00000011681	MBNL1	100	84.238	Xiphophorus_couchianus
ENSG00000152601	MBNL1	97	73.214	ENSXMAG00000013089	mbnl3	100	64.607	Xiphophorus_maculatus
ENSG00000152601	MBNL1	97	94.643	ENSXMAG00000015135	mbnl1	100	80.098	Xiphophorus_maculatus
ENSG00000152601	MBNL1	97	80.702	ENSXMAG00000004712	-	99	64.975	Xiphophorus_maculatus
ENSG00000152601	MBNL1	100	94.783	ENSXMAG00000001457	MBNL1	100	84.691	Xiphophorus_maculatus
ENSG00000152601	MBNL1	97	77.193	ENSXMAG00000012618	mbnl2	99	71.576	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0001069	regulatory region RNA binding	-	IEA	Function
GO:0001701	in utero embryonic development	-	ISS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003723	RNA binding	15257297.16946708.	IDA	Function
GO:0003725	double-stranded RNA binding	10970838.	IDA	Function
GO:0005515	protein binding	16946708.18335541.25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	10970838.15257297.16717059.	IDA	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	10970838.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0007399	nervous system development	-	ISS	Process
GO:0008380	RNA splicing	18335541.	IDA	Process
GO:0010494	cytoplasmic stress granule	18335541.	IDA	Component
GO:0030326	embryonic limb morphogenesis	-	ISS	Process
GO:0043484	regulation of RNA splicing	15257297.16946708.	IDA	Process
GO:0045445	myoblast differentiation	-	ISS	Process
GO:0046872	metal ion binding	-	IEA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26883358	Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts.	Genes Dev	2016 Feb 15	Fish L	doi: 10.1101/gad.270645.115.
25977444	The polymorphic terminal-loop of pre-miR-1307 binding with MBNL1 contributes to colorectal carcinogenesis via interference with Dicer1 recruitment.	Carcinogenesis	2015 Aug	Tang R	doi: 10.1093/carcin/bgv066

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr3	152340934	Intron	novel		0.15
BLCA	chr3	152300218	Missense_Mutation	NA	R9W	0.22
BLCA	chr3	152340480	Intron	novel		0.07
BLCA	chr3	152340974	Intron	novel		0.12
BLCA	chr3	152340421	Intron	novel		0.27
BRCA	chr3	152300356	Missense_Mutation	novel	D55N	0.13
BRCA	chr3	152463270	3'UTR	novel		0.19
BRCA	chr3	152432718	Missense_Mutation	NA	P116L	0.26
BRCA	chr3	152447653	Missense_Mutation	NA	K299E	0.16
BRCA	chr3	152300124	5'UTR	novel		0.19
BRCA	chr3	152300136	5'UTR	novel		0.06
BRCA	chr3	152300136	5'UTR	novel		0.18
CESC	chr3	152465430	3'UTR	rs771382019		0.16
CESC	chr3	152299563	5'UTR	novel		0.43
CESC	chr3	152300254	Nonsense_Mutation	NA	E21*	0.36
CESC	chr3	152300262	Missense_Mutation	NA	Q23H	0.37
CESC	chr3	152465308	3'UTR	novel		0.57
CESC	chr3	152300276	Nonsense_Mutation	NA	S28*	0.44
CESC	chr3	152300347	Missense_Mutation	NA	A52T	0.43
CESC	chr3	152432859	Missense_Mutation	novel	V163A	0.09
CESC	chr3	152464472	3'UTR	novel		0.34
CESC	chr3	152340922	Intron	novel		0.17
COAD	chr3	152455558	Intron	NA		0.34
COAD	chr3	152414997	Silent	rs199543138	T77T	0.1
COAD	chr3	152300185	5'UTR	novel		0.3
COAD	chr3	152300136	5'UTR	novel		0.24
COAD	chr3	152432823	Missense_Mutation	NA	P151Q	0.45
COAD	chr3	152445504	In_Frame_Del	novel	Q261_A268del	0.16
COAD	chr3	152300234	Missense_Mutation	NA	L14P	0.25
COAD	chr3	152415017	Missense_Mutation	NA	R84H	0.32
COAD	chr3	152414951	Missense_Mutation	NA	S62F	0.34
COAD	chr3	152445481	Missense_Mutation	NA	A250V	0.08
COAD	chr3	152458183	Intron	NA		0.3
COAD	chr3	152432878	Silent	NA	A169A	0.36
ESCA	chr3	152458191	Intron	novel		0.41
ESCA	chr3	152463308	3'UTR	novel		0.26
ESCA	chr3	152463426	3'UTR	novel		0.21
ESCA	chr3	152299120	Intron	novel		0.13
ESCA	chr3	152462874	3'UTR	novel		0.82
ESCA	chr3	152415043	Missense_Mutation	novel	M93L	0.3	zf-CCCH
GBM	chr3	152455569	Intron	novel		0.38
GBM	chr3	152445307	Missense_Mutation	novel	N192I	0.24
GBM	chr3	152300267	Missense_Mutation	NA	G25E	0.29
GBM	chr3	152414962	Missense_Mutation	NA	C66S	0.04
HNSC	chr3	152455564	Intron	rs202021492		0.23
HNSC	chr3	152340986	Intron	novel		0.14
HNSC	chr3	152445475	Missense_Mutation	novel	K248T	0.49
KIRC	chr3	152300278	Missense_Mutation	rs770696564	R29W	0.06
KIRP	chr3	152414990	Missense_Mutation	novel	L75S	0.61
KIRP	chr3	152300074	5'UTR	novel		0.43
KIRP	chr3	152445473	Silent	NA	I247I	0.25
LAML	chr3	152300136	5'UTR	novel		0.17
LIHC	chr3	152455549	Intron	novel		0.32
LIHC	chr3	152456316	Silent	novel	T355T	0.33
LIHC	chr3	152415017	Missense_Mutation	NA	R84H	0.36
LIHC	chr3	152446742	Missense_Mutation	novel	E282D	0.25
LUAD	chr3	152340935	Intron	novel		0.11
LUAD	chr3	152432905	Silent	novel	R178R	0.42
LUAD	chr3	152459346	Splice_Site	novel		0.19
LUAD	chr3	152446716	Missense_Mutation	novel	V274F	0.15
LUAD	chr3	152415098	Missense_Mutation	novel	P111L	0.12
LUAD	chr3	152415043	Frame_Shift_Del	novel	*M93Wfs10**	0.18	zf-CCCH
LUSC	chr3	152432894	Frame_Shift_Del	novel	*K175Nfs2**	0.07
LUSC	chr3	152456341	Missense_Mutation	NA	A364S	0.15
LUSC	chr3	152340395	Intron	novel		0.34
LUSC	chr3	152340406	Intron	novel		0.27
LUSC	chr3	152340970	Intron	novel		0.53
LUSC	chr3	152432758	Silent	novel	S129S	0.21
LUSC	chr3	152432765	Missense_Mutation	rs780538995	A132T	0.19
LUSC	chr3	152340406	Intron	novel		0.41
LUSC	chr3	152432739	Missense_Mutation	novel	S123N	0.24
LUSC	chr3	152415065	Missense_Mutation	NA	M100T	0.43	zf-CCCH
LUSC	chr3	152300137	5'UTR	novel		0.33
OV	chr3	152300276	Nonsense_Mutation	NA	S28*	0.72
OV	chr3	152300136	5'UTR	novel		0.16
OV	chr3	152300288	Missense_Mutation	novel	T32R	0.04
OV	chr3	152432765	Missense_Mutation	NA	A132S	0.15
OV	chr3	152300136	5'UTR	novel		0.17
PAAD	chr3	152432765	Missense_Mutation	rs780538995	A132T	0.23
READ	chr3	152300037	5'UTR	novel		0.32
READ	chr3	152300347	Missense_Mutation	NA	A52T	0.45
READ	chr3	152445485	Silent	novel	Q251Q	0.13
SARC	chr3	152299038	Intron	novel		0.57
SARC	chr3	152300218	Missense_Mutation	NA	R9W	0.36
SKCM	chr3	152300084	5'UTR	novel		0.5
SKCM	chr3	152300338	Frame_Shift_Ins	novel	*I51Sfs6**	0.42
SKCM	chr3	152456269	Missense_Mutation	NA	P340S	0.81
SKCM	chr3	152432714	Splice_Region	novel		0.26
SKCM	chr3	152432801	Silent	NA	L144L	0.29
SKCM	chr3	152432807	Missense_Mutation	NA	P146S	0.45
SKCM	chr3	152432878	Silent	novel	A169A	0.51
SKCM	chr3	152445316	Missense_Mutation	NA	R195Q	0.33
STAD	chr3	152300280	Silent	rs773981630	R29R	0.21
STAD	chr3	152456276	In_Frame_Ins	novel	H343_T346dup	0.08
STAD	chr3	152415071	Missense_Mutation	NA	L102P	0.05	zf-CCCH
STAD	chr3	152445298	Missense_Mutation	NA	Q189R	0.14
STAD	chr3	152300368	Splice_Site	NA	X58_splice	0.11
STAD	chr3	152455565	Intron	novel		0.32
STAD	chr3	152432868	Missense_Mutation	NA	P166H	0.1
STAD	chr3	152445370	Missense_Mutation	NA	T213I	0.14
STAD	chr3	152300136	5'UTR	novel		0.23
STAD	chr3	152447689	Missense_Mutation	rs748628776	A311T	0.13
UCEC	chr3	152300136	5'UTR	novel		0.45
UCEC	chr3	152300218	Missense_Mutation	NA	R9W	0.16
UCEC	chr3	152300347	Missense_Mutation	NA	A52T	0.11
UCEC	chr3	152415017	Missense_Mutation	NA	R84H	0.14
UCEC	chr3	152432909	Missense_Mutation	novel	D180N	0.33
UCEC	chr3	152463615	3'UTR	novel		0.36
UCEC	chr3	152463255	3'UTR	novel		0.57
UCEC	chr3	152415039	Missense_Mutation	NA	K91N	0.12	zf-CCCH
UCEC	chr3	152432765	Missense_Mutation	rs780538995	A132T	0.17
UCEC	chr3	152445289	Missense_Mutation	novel	R186Q	0.07
UCEC	chr3	152300334	Silent	novel	N47N	0.38
UCEC	chr3	152445333	Missense_Mutation	novel	R201W	0.21
UCEC	chr3	152447644	Missense_Mutation	novel	P296T	0.27
UCEC	chr3	152299210	Intron	novel		0.26
UCEC	chr3	152463023	3'UTR	novel		0.16
UCEC	chr3	152464281	3'UTR	novel		0.37
UCEC	chr3	152446740	Missense_Mutation	novel	E282K	0.19
UCEC	chr3	152340934	Intron	novel		0.55
UCEC	chr3	152459321	Silent	NA	Q387Q	0.24
UCEC	chr3	152300162	5'UTR	novel		0.26
UCEC	chr3	152447654	Missense_Mutation	NA	K299R	0.36
UCEC	chr3	152459330	3'UTR	novel		0.39
UCEC	chr3	152414980	Frame_Shift_Del	NA	*P73Hfs3**	0.37
UCEC	chr3	152456335	Frame_Shift_Del	novel	*F362Sfs12**	0.37
UCEC	chr3	152414958	Silent	novel	E64E	0.08
UCEC	chr3	152414958	Missense_Mutation	novel	E64D	0.09
UCEC	chr3	152415109	Missense_Mutation	rs754733825	V115M	0.32
UCEC	chr3	152463516	3'UTR	novel		0.32
UCEC	chr3	152464719	3'UTR	rs540894317		0.39
UCEC	chr3	152464875	3'UTR	novel		0.46
UCEC	chr3	152299498	5'UTR	novel		0.15
UCEC	chr3	152463520	3'UTR	novel		0.16
UCEC	chr3	152463828	3'UTR	novel		0.24
UCEC	chr3	152463984	3'UTR	novel		0.13
UCEC	chr3	152300137	5'UTR	novel		0.33
UCEC	chr3	152464237	3'UTR	novel		0.5
UCEC	chr3	152464245	3'UTR	novel		0.6
UCEC	chr3	152447668	Frame_Shift_Ins	novel	*T306Nfs9**	0.29
UCEC	chr3	152459312	Nonsense_Mutation	novel	Y384*	0.35
UCEC	chr3	152464100	3'UTR	novel		0.39
UCEC	chr3	152464602	3'UTR	novel		0.26
UCEC	chr3	152465667	3'UTR	novel		0.46
UCEC	chr3	152462908	3'UTR	novel		0.38
UCEC	chr3	152464305	3'UTR	novel		0.29
UCEC	chr3	152299211	Intron	novel		0.22
UCEC	chr3	152463373	3'UTR	novel		0.4
UCEC	chr3	152464759	3'UTR	novel		0.41
UCEC	chr3	152447731	Missense_Mutation	NA	A325T	0.45
UCEC	chr3	152463428	3'UTR	novel		0.38
UCEC	chr3	152463723	3'UTR	novel		0.36
UCEC	chr3	152300136	5'UTR	novel		0.35
UCEC	chr3	152463975	3'UTR	novel		0.23
UCEC	chr3	152464237	3'UTR	novel		0.33
UCEC	chr3	152432765	Missense_Mutation	rs780538995	A132T	0.21
UCEC	chr3	152459346	Splice_Site	novel		0.14
UCEC	chr3	152456305	Missense_Mutation	rs773149172	A352T	0.44
UCEC	chr3	152463545	3'UTR	novel		0.3
UCEC	chr3	152463379	3'UTR	novel		0.24
UCEC	chr3	152463603	3'UTR	novel		0.18
UCEC	chr3	152465477	3'UTR	novel		0.46
UCEC	chr3	152455557	Intron	novel		0.38
UCEC	chr3	152432765	Missense_Mutation	rs780538995	A132T	0.56
UCEC	chr3	152445316	Missense_Mutation	NA	R195Q	0.14
UCEC	chr3	152459327	Nonstop_Mutation	novel	389Yext5	0.53
UCEC	chr3	152463374	3'UTR	novel		0.49
UCEC	chr3	152463882	3'UTR	novel		0.11
UCEC	chr3	152462981	3'UTR	novel		0.18
UCEC	chr3	152464405	3'UTR	novel		0.25
UCEC	chr3	152432828	Missense_Mutation	novel	A153T	0.04
UCEC	chr3	152446732	Missense_Mutation	rs760190490	R279Q	0.47
UCEC	chr3	152300309	Missense_Mutation	novel	P39H	0.44
UCEC	chr3	152335166	Intron	novel		0.24
UCEC	chr3	152415108	Silent	novel	P114P	0.14
UCEC	chr3	152445281	Splice_Site	novel	X184_splice	0.35
UCEC	chr3	152446757	Frame_Shift_Ins	novel	*G288Qfs41**	0.05
UCEC	chr3	152432722	Frame_Shift_Ins	novel	*S119Ffs16**	0.21
UCEC	chr3	152464033	3'UTR	novel		0.38
UCEC	chr3	152464398	3'UTR	novel		0.5
UCEC	chr3	152464014	3'UTR	novel		0.27
UCEC	chr3	152445423	Missense_Mutation	novel	R231W	0.23
UCEC	chr3	152340989	Intron	novel		0.28
UCEC	chr3	152464237	3'UTR	novel		0.63
UCEC	chr3	152414997	Silent	rs199543138	T77T	0.35
UCEC	chr3	152463028	3'UTR	novel		0.4
UCEC	chr3	152464010	3'UTR	novel		0.46
UCEC	chr3	152464305	3'UTR	novel		0.31
UCEC	chr3	152447724	Missense_Mutation	novel	Q322H	0.22
UCEC	chr3	152465694	3'UTR	novel		0.3
UCS	chr3	152456307	Silent	novel	A352A	0.37

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRC	DEL	0.1117	0.11092
KIRP	AMP	0.316	0.15981
PAAD	AMP	0.0924	0.16151

Survival Analysis

Cancer	P-value	Q-value
THYM	0.043	Kaplan-Meier Survival Analysis
STAD	0.034	Kaplan-Meier Survival Analysis
SARC	0.0083	Kaplan-Meier Survival Analysis
HNSC	0.021	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
LUSC	0.003	Kaplan-Meier Survival Analysis
BRCA	0.045	Kaplan-Meier Survival Analysis
KIRP	0.00085	Kaplan-Meier Survival Analysis
PAAD	0.026	Kaplan-Meier Survival Analysis
CESC	0.0017	Kaplan-Meier Survival Analysis
KICH	0.0059	Kaplan-Meier Survival Analysis
GBM	0.012	Kaplan-Meier Survival Analysis
LIHC	0.04	Kaplan-Meier Survival Analysis
LGG	0.0075	Kaplan-Meier Survival Analysis
CHOL	0.017	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742