EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000152684 (Gene tree)
Gene ID: 53918
Gene Symbol: PELO
Alias: N
Full Name: pelota mRNA surveillance and ribosome rescue factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 16,107 bases
Position: chr5:52,787,940-52,804,046
Accession: 8829
RBP type: canonical RBP
Summary: This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000274311	eRF1_2	PF03464.15	1e-36	1	1
ENSP00000274311	eRF1_3	PF03465.15	3.1e-26	1	1
ENSP00000274311	eRF1_1	PF03463.15	9.4e-53	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000274311	PELO-201	4349	-	ENSP00000274311	385 (aa)	-	Q9BRX2
ENST00000506949	PELO-202	888	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000152684's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03015	mRNA surveillance pathway	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000152684	rs1499280	5	52801055	A	High light scatter reticulocyte percentage of red cells	27863252	[0.067-0.093] unit decrease	0.07983775	EFO_0007986
ENSG00000152684	rs1499280	5	52801055	A	Reticulocyte count	27863252	[0.064-0.089] unit decrease	0.07665564	EFO_0007986
ENSG00000152684	rs7708122	5	52797097	?	Pneumonia	28928442	[0.37-0.92] unit decrease	0.6445	EFO_0008410
ENSG00000152684	rs6879147	5	52792018	?	Serum total protein level	29403010	[0.022-0.044] unit increase novel	0.03335	EFO_0007937
ENSG00000152684	rs1499280	5	52801055	A	Reticulocyte fraction of red cells	27863252	[0.065-0.091] unit decrease	0.07831162	EFO_0007986
ENSG00000152684	rs1499280	5	52801055	A	Immature fraction of reticulocytes	27863252	[0.047-0.072] unit decrease	0.05919002	EFO_0007986
ENSG00000152684	rs1499280	5	52801055	A	High light scatter reticulocyte count	27863252	[0.066-0.092] unit decrease	0.07906187	EFO_0007986

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000152684's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000152684	PELO	64	80.972	ENSAPOG00000023700	-	90	80.972	Acanthochromis_polyacanthus
ENSG00000152684	PELO	100	80.260	ENSAPOG00000023072	pelo	100	80.260	Acanthochromis_polyacanthus
ENSG00000152684	PELO	64	80.972	ENSAPOG00000000616	pelo	90	80.972	Acanthochromis_polyacanthus
ENSG00000152684	PELO	100	98.182	ENSAMEG00000007734	PELO	100	98.182	Ailuropoda_melanoleuca
ENSG00000152684	PELO	97	77.212	ENSACIG00000014386	pelo	97	82.249	Amphilophus_citrinellus
ENSG00000152684	PELO	100	80.519	ENSAOCG00000023717	pelo	100	80.519	Amphiprion_ocellaris
ENSG00000152684	PELO	100	80.519	ENSAPEG00000011235	pelo	100	80.519	Amphiprion_percula
ENSG00000152684	PELO	100	81.818	ENSATEG00000019550	pelo	100	81.818	Anabas_testudineus
ENSG00000152684	PELO	77	84.228	ENSAPLG00000013265	PELO	100	84.228	Anas_platyrhynchos
ENSG00000152684	PELO	98	89.894	ENSACAG00000004352	PELO	100	89.610	Anolis_carolinensis
ENSG00000152684	PELO	100	98.961	ENSANAG00000014096	PELO	100	98.961	Aotus_nancymaae
ENSG00000152684	PELO	100	80.260	ENSACLG00000010305	pelo	100	80.260	Astatotilapia_calliptera
ENSG00000152684	PELO	97	81.233	ENSAMXG00000020299	pelo	100	80.311	Astyanax_mexicanus
ENSG00000152684	PELO	100	98.442	ENSBTAG00000003268	PELO	99	98.442	Bos_taurus
ENSG00000152684	PELO	99	58.268	WBGene00011280	pelo-1	100	58.268	Caenorhabditis_elegans
ENSG00000152684	PELO	100	99.221	ENSCJAG00000035190	PELO	100	99.221	Callithrix_jacchus
ENSG00000152684	PELO	100	98.442	ENSCAFG00020023234	PELO	100	98.442	Canis_lupus_dingo
ENSG00000152684	PELO	100	98.182	ENSCHIG00000016410	PELO	99	98.182	Capra_hircus
ENSG00000152684	PELO	100	98.701	ENSTSYG00000005203	PELO	100	98.701	Carlito_syrichta
ENSG00000152684	PELO	100	98.182	ENSCPOG00000027406	PELO	100	98.182	Cavia_porcellus
ENSG00000152684	PELO	100	99.221	ENSCCAG00000035600	PELO	100	99.221	Cebus_capucinus
ENSG00000152684	PELO	100	99.481	ENSCATG00000011829	PELO	100	99.481	Cercocebus_atys
ENSG00000152684	PELO	100	97.662	ENSCLAG00000005043	PELO	100	97.662	Chinchilla_lanigera
ENSG00000152684	PELO	100	99.481	ENSCSAG00000016692	PELO	100	99.481	Chlorocebus_sabaeus
ENSG00000152684	PELO	100	97.922	ENSCHOG00000000523	PELO	100	97.922	Choloepus_hoffmanni
ENSG00000152684	PELO	98	93.351	ENSCPBG00000007544	PELO	100	92.987	Chrysemys_picta_bellii
ENSG00000152684	PELO	97	69.169	ENSCING00000001979	-	100	69.610	Ciona_intestinalis
ENSG00000152684	PELO	100	69.610	ENSCSAVG00000006158	-	100	69.610	Ciona_savignyi
ENSG00000152684	PELO	100	99.481	ENSCANG00000023382	PELO	100	99.481	Colobus_angolensis_palliatus
ENSG00000152684	PELO	100	95.325	ENSCGRG00001024665	Pelo	100	95.325	Cricetulus_griseus_chok1gshd
ENSG00000152684	PELO	100	96.623	ENSCGRG00000004570	Pelo	100	96.623	Cricetulus_griseus_crigri
ENSG00000152684	PELO	100	80.000	ENSCSEG00000008807	pelo	100	80.000	Cynoglossus_semilaevis
ENSG00000152684	PELO	100	81.299	ENSCVAG00000016082	pelo	100	81.299	Cyprinodon_variegatus
ENSG00000152684	PELO	100	82.078	ENSDARG00000055477	pelo	100	82.078	Danio_rerio
ENSG00000152684	PELO	100	95.855	ENSDNOG00000036721	PELO	100	95.855	Dasypus_novemcinctus
ENSG00000152684	PELO	100	97.403	ENSDORG00000016689	Pelo	100	97.403	Dipodomys_ordii
ENSG00000152684	PELO	96	67.116	FBgn0011207	pelo	96	66.755	Drosophila_melanogaster
ENSG00000152684	PELO	71	81.287	ENSEBUG00000004955	pelo	99	81.287	Eptatretus_burgeri
ENSG00000152684	PELO	100	98.182	ENSEASG00005013348	PELO	100	98.182	Equus_asinus_asinus
ENSG00000152684	PELO	100	80.519	ENSELUG00000023229	pelo	100	80.519	Esox_lucius
ENSG00000152684	PELO	100	97.922	ENSFCAG00000032341	PELO	100	97.922	Felis_catus
ENSG00000152684	PELO	100	94.026	ENSFALG00000004559	PELO	100	94.026	Ficedula_albicollis
ENSG00000152684	PELO	74	97.183	ENSFDAG00000002076	PELO	88	97.183	Fukomys_damarensis
ENSG00000152684	PELO	100	79.481	ENSFHEG00000009769	pelo	100	79.481	Fundulus_heteroclitus
ENSG00000152684	PELO	98	79.841	ENSGMOG00000005849	pelo	100	79.481	Gadus_morhua
ENSG00000152684	PELO	100	80.519	ENSGAFG00000019350	pelo	100	80.519	Gambusia_affinis
ENSG00000152684	PELO	100	80.260	ENSGACG00000007245	pelo	100	80.260	Gasterosteus_aculeatus
ENSG00000152684	PELO	98	93.617	ENSGAGG00000004018	PELO	100	93.247	Gopherus_agassizii
ENSG00000152684	PELO	100	99.481	ENSGGOG00000012635	PELO	100	99.481	Gorilla_gorilla
ENSG00000152684	PELO	100	80.260	ENSHBUG00000005866	pelo	100	80.260	Haplochromis_burtoni
ENSG00000152684	PELO	100	97.662	ENSHGLG00000005932	PELO	100	97.662	Heterocephalus_glaber_female
ENSG00000152684	PELO	100	95.325	ENSHGLG00100017627	PELO	100	95.325	Heterocephalus_glaber_male
ENSG00000152684	PELO	100	77.662	ENSHCOG00000016782	pelo	100	77.662	Hippocampus_comes
ENSG00000152684	PELO	100	79.740	ENSIPUG00000020627	pelo	100	79.740	Ictalurus_punctatus
ENSG00000152684	PELO	100	98.182	ENSSTOG00000027378	PELO	100	98.182	Ictidomys_tridecemlineatus
ENSG00000152684	PELO	100	94.026	ENSJJAG00000015032	Pelo	100	94.026	Jaculus_jaculus
ENSG00000152684	PELO	100	81.039	ENSKMAG00000021305	pelo	100	81.039	Kryptolebias_marmoratus
ENSG00000152684	PELO	100	80.779	ENSLBEG00000022399	pelo	100	80.779	Labrus_bergylta
ENSG00000152684	PELO	100	98.442	ENSLAFG00000020551	PELO	100	98.442	Loxodonta_africana
ENSG00000152684	PELO	100	99.481	ENSMFAG00000000651	PELO	100	99.481	Macaca_fascicularis
ENSG00000152684	PELO	100	99.481	ENSMMUG00000039101	PELO	100	99.481	Macaca_mulatta
ENSG00000152684	PELO	100	99.481	ENSMNEG00000035538	PELO	100	99.481	Macaca_nemestrina
ENSG00000152684	PELO	100	99.481	ENSMLEG00000039113	PELO	100	99.481	Mandrillus_leucophaeus
ENSG00000152684	PELO	97	83.110	ENSMAMG00000013260	pelo	100	82.857	Mastacembelus_armatus
ENSG00000152684	PELO	100	80.260	ENSMZEG00005014258	pelo	100	80.260	Maylandia_zebra
ENSG00000152684	PELO	100	96.623	ENSMAUG00000009770	Pelo	100	96.623	Mesocricetus_auratus
ENSG00000152684	PELO	100	98.701	ENSMICG00000044040	PELO	100	98.701	Microcebus_murinus
ENSG00000152684	PELO	100	96.883	ENSMOCG00000017554	Pelo	100	96.883	Microtus_ochrogaster
ENSG00000152684	PELO	100	79.221	ENSMMOG00000001324	pelo	100	79.221	Mola_mola
ENSG00000152684	PELO	100	82.338	ENSMALG00000008194	pelo	100	82.338	Monopterus_albus
ENSG00000152684	PELO	100	96.883	MGP_CAROLIEiJ_G0018915	Pelo	100	96.883	Mus_caroli
ENSG00000152684	PELO	100	96.883	ENSMUSG00000042275	Pelo	100	96.883	Mus_musculus
ENSG00000152684	PELO	100	97.143	MGP_PahariEiJ_G0015985	Pelo	100	97.143	Mus_pahari
ENSG00000152684	PELO	100	96.883	MGP_SPRETEiJ_G0019793	Pelo	100	96.883	Mus_spretus
ENSG00000152684	PELO	100	95.065	ENSMLUG00000024132	PELO	100	95.065	Myotis_lucifugus
ENSG00000152684	PELO	100	97.662	ENSNGAG00000019331	Pelo	100	97.662	Nannospalax_galili
ENSG00000152684	PELO	100	80.260	ENSNBRG00000011799	pelo	100	80.260	Neolamprologus_brichardi
ENSG00000152684	PELO	100	99.481	ENSNLEG00000035970	PELO	100	99.481	Nomascus_leucogenys
ENSG00000152684	PELO	100	94.545	ENSMEUG00000005468	PELO	100	94.545	Notamacropus_eugenii
ENSG00000152684	PELO	98	97.098	ENSOPRG00000018793	PELO	100	97.098	Ochotona_princeps
ENSG00000152684	PELO	100	96.883	ENSODEG00000017579	PELO	100	96.883	Octodon_degus
ENSG00000152684	PELO	96	80.811	ENSONIG00000011511	pelo	100	80.260	Oreochromis_niloticus
ENSG00000152684	PELO	100	98.182	ENSOCUG00000023902	PELO	100	98.182	Oryctolagus_cuniculus
ENSG00000152684	PELO	100	81.039	ENSORLG00000005827	pelo	100	81.039	Oryzias_latipes
ENSG00000152684	PELO	100	81.299	ENSORLG00020016456	pelo	100	81.299	Oryzias_latipes_hni
ENSG00000152684	PELO	100	81.558	ENSORLG00015014447	pelo	100	81.558	Oryzias_latipes_hsok
ENSG00000152684	PELO	100	81.299	ENSOMEG00000021567	pelo	100	81.299	Oryzias_melastigma
ENSG00000152684	PELO	100	97.922	ENSOGAG00000027940	PELO	100	97.922	Otolemur_garnettii
ENSG00000152684	PELO	100	98.442	ENSOARG00000008324	PELO	99	98.442	Ovis_aries
ENSG00000152684	PELO	100	99.481	ENSPPAG00000038951	PELO	100	99.481	Pan_paniscus
ENSG00000152684	PELO	100	97.922	ENSPPRG00000018800	PELO	100	97.922	Panthera_pardus
ENSG00000152684	PELO	100	97.922	ENSPTIG00000019988	PELO	100	97.922	Panthera_tigris_altaica
ENSG00000152684	PELO	100	99.481	ENSPTRG00000034409	PELO	100	99.481	Pan_troglodytes
ENSG00000152684	PELO	100	99.481	ENSPANG00000010902	PELO	100	99.481	Papio_anubis
ENSG00000152684	PELO	100	82.078	ENSPKIG00000015190	pelo	100	82.078	Paramormyrops_kingsleyae
ENSG00000152684	PELO	98	93.085	ENSPSIG00000004971	PELO	100	92.727	Pelodiscus_sinensis
ENSG00000152684	PELO	67	78.682	ENSPMGG00000014561	pelo	95	78.682	Periophthalmus_magnuspinnatus
ENSG00000152684	PELO	100	96.623	ENSPEMG00000015584	Pelo	100	96.623	Peromyscus_maniculatus_bairdii
ENSG00000152684	PELO	100	96.364	ENSPCIG00000004880	PELO	100	96.364	Phascolarctos_cinereus
ENSG00000152684	PELO	100	81.299	ENSPFOG00000007277	pelo	100	81.299	Poecilia_formosa
ENSG00000152684	PELO	100	81.558	ENSPLAG00000020787	pelo	100	81.558	Poecilia_latipinna
ENSG00000152684	PELO	100	81.299	ENSPMEG00000016964	pelo	100	81.299	Poecilia_mexicana
ENSG00000152684	PELO	100	81.558	ENSPREG00000023071	pelo	100	81.558	Poecilia_reticulata
ENSG00000152684	PELO	100	99.221	ENSPPYG00000015451	PELO	96	99.221	Pongo_abelii
ENSG00000152684	PELO	100	98.701	ENSPCOG00000021178	PELO	100	98.701	Propithecus_coquereli
ENSG00000152684	PELO	100	80.260	ENSPNYG00000017325	pelo	100	80.260	Pundamilia_nyererei
ENSG00000152684	PELO	97	81.769	ENSPNAG00000012458	pelo	99	80.519	Pygocentrus_nattereri
ENSG00000152684	PELO	100	97.143	ENSRNOG00000061128	Pelo	100	97.143	Rattus_norvegicus
ENSG00000152684	PELO	100	99.481	ENSRBIG00000007299	PELO	100	99.481	Rhinopithecus_bieti
ENSG00000152684	PELO	100	99.481	ENSRROG00000035507	PELO	100	99.481	Rhinopithecus_roxellana
ENSG00000152684	PELO	98	34.447	YNL001W	-	99	34.447	Saccharomyces_cerevisiae
ENSG00000152684	PELO	100	98.961	ENSSBOG00000036140	PELO	100	98.961	Saimiri_boliviensis_boliviensis
ENSG00000152684	PELO	63	95.902	ENSSHAG00000010770	PELO	100	95.902	Sarcophilus_harrisii
ENSG00000152684	PELO	98	83.289	ENSSFOG00015013399	pelo	100	82.857	Scleropages_formosus
ENSG00000152684	PELO	100	80.260	ENSSMAG00000017171	pelo	100	80.260	Scophthalmus_maximus
ENSG00000152684	PELO	100	80.519	ENSSDUG00000022938	pelo	100	80.519	Seriola_dumerili
ENSG00000152684	PELO	100	76.883	ENSSLDG00000017884	pelo	100	76.883	Seriola_lalandi_dorsalis
ENSG00000152684	PELO	98	91.755	ENSSPUG00000005545	PELO	100	91.429	Sphenodon_punctatus
ENSG00000152684	PELO	98	81.698	ENSSPAG00000008501	pelo	100	81.299	Stegastes_partitus
ENSG00000152684	PELO	100	96.623	ENSSSCG00000016884	PELO	100	96.623	Sus_scrofa
ENSG00000152684	PELO	100	94.026	ENSTGUG00000002416	PELO	100	94.026	Taeniopygia_guttata
ENSG00000152684	PELO	100	79.740	ENSTRUG00000005809	pelo	100	79.740	Takifugu_rubripes
ENSG00000152684	PELO	100	80.519	ENSTNIG00000018937	pelo	100	80.519	Tetraodon_nigroviridis
ENSG00000152684	PELO	100	97.922	ENSTTRG00000001857	PELO	100	97.922	Tursiops_truncatus
ENSG00000152684	PELO	100	98.182	ENSUAMG00000002535	PELO	100	98.182	Ursus_americanus
ENSG00000152684	PELO	100	98.182	ENSUMAG00000005809	PELO	100	98.182	Ursus_maritimus
ENSG00000152684	PELO	100	98.442	ENSVPAG00000001113	PELO	100	98.442	Vicugna_pacos
ENSG00000152684	PELO	100	98.442	ENSVVUG00000025499	PELO	100	98.442	Vulpes_vulpes
ENSG00000152684	PELO	81	81.613	ENSXETG00000018368	pelo	100	79.755	Xenopus_tropicalis
ENSG00000152684	PELO	100	81.558	ENSXMAG00000018474	pelo	100	81.558	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001833	inner cell mass cell proliferation	-	IEA	Process
GO:0004519	endonuclease activity	-	IEA	Function
GO:0005515	protein binding	20406461.25416956.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0007049	cell cycle	-	IEA	Process
GO:0007492	endoderm development	-	IEA	Process
GO:0019827	stem cell population maintenance	-	IEA	Process
GO:0030513	positive regulation of BMP signaling pathway	-	IEA	Process
GO:0032790	ribosome disassembly	21873635.	IBA	Process
GO:0043022	ribosome binding	21873635.	IBA	Function
GO:0046872	metal ion binding	-	IEA	Function
GO:0051276	chromosome organization	-	IEA	Process
GO:0051301	cell division	-	IEA	Process
GO:0060231	mesenchymal to epithelial transition	-	IEA	Process
GO:0070481	nuclear-transcribed mRNA catabolic process, non-stop decay	-	IEA	Process
GO:0070651	nonfunctional rRNA decay	21873635.	IBA	Process
GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay	21873635.	IBA	Process
GO:0071025	RNA surveillance	-	IEA	Process
GO:0090305	nucleic acid phosphodiester bond hydrolysis	-	IEA	Process