EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000153774 (Gene tree)
Gene ID: 10428
Gene Symbol: CFDP1
Alias: BCNT|p97|CP27|SWC5|Yeti|CENP-29
Full Name: craniofacial development protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 139,815 bases
Position: chr16:75,293,698-75,433,512
Accession: 1873
RBP type: non-canonical RBP
Summary: (Craniofacial Development Protein 1) is a Protein Coding gene. Diseases associated with CFDP1 include Lagophthalmos.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000566254	CFDP1-206	342	-	ENSP00000455564	50 (aa)	-	H3BQ17
ENST00000570279	CFDP1-210	349	-	-	- (aa)	-	-
ENST00000564793	CFDP1-204	457	-	-	- (aa)	-	-
ENST00000570103	CFDP1-209	663	-	-	- (aa)	-	-
ENST00000283882	CFDP1-201	1275	XM_011522814	ENSP00000283882	299 (aa)	XP_011521116	Q9UEE9
ENST00000562602	CFDP1-202	699	-	-	- (aa)	-	-
ENST00000564286	CFDP1-203	775	-	-	- (aa)	-	-
ENST00000569341	CFDP1-208	454	-	ENSP00000462862	19 (aa)	-	J3KT89
ENST00000566901	CFDP1-207	1167	-	-	- (aa)	-	-
ENST00000565646	CFDP1-205	608	-	-	- (aa)	-	-
ENST00000612761	CFDP1-211	395	-	ENSP00000481200	17 (aa)	-	A0A087WXQ2

Gene Model

Click here to download ENSG00000153774's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000153774	Platelet Function Tests	2.8082300E-005	-
ENSG00000153774	Plaque, Atherosclerotic	1.7310000E-005	21909108
ENSG00000153774	Plaque, Atherosclerotic	3.9280000E-006	21909108
ENSG00000153774	Plaque, Atherosclerotic	2.2040000E-005	21909108
ENSG00000153774	Plaque, Atherosclerotic	5.4590000E-006	21909108
ENSG00000153774	Plaque, Atherosclerotic	1.9440000E-006	21909108
ENSG00000153774	Lung Volume Measurements	2E-11	21946350
ENSG00000153774	Respiratory Function Tests	2E-11	21946350
ENSG00000153774	Lung Volume Measurements	2E-8	23284291
ENSG00000153774	Pulmonary Disease, Chronic Obstructive	1E-11	28166215
ENSG00000153774	Lung Volume Measurements	4E-10	28166213
ENSG00000153774	Forced Expiratory Volume	4E-6	28166213
ENSG00000153774	Migraine Disorders	6E-8	27182965

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000153774	rs77505915	16	75408245	T	Migraine	27322543	[1.03-1.06]	1.05	EFO_0003821
ENSG00000153774	rs2865531	16	75356418	?	Pulmonary function (smoking interaction)	23284291			EFO_0003892\|EFO_0005671\|EFO_0004713
ENSG00000153774	rs11640018	16	75294410	G	Moyamoya disease	29273593	[NR]	1.2345679	Orphanet_2573
ENSG00000153774	rs12930452	16	75428157	A	Coronary artery disease	29212778	[0.038-0.066] unit decrease	0.052	EFO_0000378
ENSG00000153774	rs4888378	16	75298143	A	Coronary artery disease	29212778	[0.033-0.055] unit decrease	0.0439	EFO_0000378
ENSG00000153774	rs8046696	16	75408245	T	Coronary artery disease	29212778	[0.037-0.059] unit decrease	0.0479	EFO_0000378
ENSG00000153774	rs17696696	16	75359454	G	Aortic root size	28394258	[0.01-0.022] cm decrease	0.016	EFO_0005037
ENSG00000153774	rs3743609	16	75433123	C	Lung function (FEV1)	28166213	[0.017-0.045] unit decrease	0.031	EFO_0004314
ENSG00000153774	rs3743609	16	75433123	C	Lung function (FEV1/FVC)	28166213	[0.028-0.056] unit decrease	0.042	EFO_0004713
ENSG00000153774	rs2865531	16	75356418	T	Pulmonary function	21946350	[0.021-0.041] unit increase	0.031	EFO_0003892\|EFO_0004713
ENSG00000153774	rs200914569	16	75408247	?	Migraine	27182965	[1.03-1.06]	1.0449321	EFO_0003821
ENSG00000153774	rs11643209	16	75297146	T	Systolic blood pressure	28135244	[0.24-0.44] unit decrease	0.339	EFO_0006335
ENSG00000153774	rs4888411	16	75409285	?	Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test)	29455858			EFO_0006527\|EFO_0006336
ENSG00000153774	rs4888411	16	75409285	?	Systolic blood pressure x smoking status (current vs non-current) interaction (2df test)	29455858			EFO_0006527\|EFO_0006335
ENSG00000153774	rs4888411	16	75409285	?	Systolic blood pressure x smoking status (current vs non-current) interaction (2df test)	29455858			EFO_0006527\|EFO_0006335
ENSG00000153774	rs4888411	16	75409285	?	Systolic blood pressure x smoking status (current vs non-current) interaction (2df test)	29455858			EFO_0006527\|EFO_0006335
ENSG00000153774	rs4888411	16	75409285	?	Systolic blood pressure x smoking status (ever vs never) interaction (2df test)	29455858			EFO_0006527\|EFO_0006335
ENSG00000153774	rs4888411	16	75409285	?	Systolic blood pressure x smoking status (ever vs never) interaction (2df test)	29455858			EFO_0006527\|EFO_0006335
ENSG00000153774	rs4888411	16	75409285	?	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	29455858			EFO_0006527\|EFO_0006336
ENSG00000153774	rs113309773	16	75398789	?	Carotid plaque	30510157	[0.088-0.164] unit decrease	0.1259	EFO_0009783
ENSG00000153774	rs766522	16	75390212	?	Cardiovascular disease	30595370			EFO_0000319
ENSG00000153774	rs192422186	16	75394552	?	Aspartate aminotransferase levels in low alcohol consumption	30589442	[0.085-0.21] unit increase	0.1473	EFO_0004736\|EFO_0007878
ENSG00000153774	rs12449170	16	75429114	T	Pulse pressure	30578418	[0.18-0.28] mmHg increase	0.2264	EFO_0005763
ENSG00000153774	rs12449170	16	75429114	T	Systolic blood pressure	30578418	[0.24-0.37] mmHg increase	0.3022	EFO_0006335
ENSG00000153774	rs11858992	16	75377547	A	FEV1	30804560	[0.018-0.027] unit increase	0.0224	EFO_0004314
ENSG00000153774	rs11858992	16	75377547	A	Lung function (FEV1/FVC)	30804560	[0.033-0.043] unit increase	0.038	EFO_0004713
ENSG00000153774	rs11858992	16	75377547	A	Peak expiratory flow	30804560	[0.025-0.035] unit increase	0.0303
ENSG00000153774	rs35261357	16	75410674	C	Systolic blood pressure	27841878	unit decrease	0.265	EFO_0006335
ENSG00000153774	rs35261357	16	75410674	C	Pulse pressure	27841878	unit decrease	0.216	EFO_0005763
ENSG00000153774	rs4888420	16	75429100	?	Lung function (FEV1/FVC)	30595370			EFO_0004713
ENSG00000153774	rs1549306	16	75381443	?	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy)	30940143			EFO_0004325\|EFO_0000341
ENSG00000153774	rs8046697	16	75408246	?	Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy)	30940143			EFO_0000341\|EFO_0000378

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000153774's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000153774	CFDP1	100	81.271	ENSMUSG00000031954	Cfdp1	100	80.602	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000777	condensed chromosome kinetochore	-	IEA	Component
GO:0003674	molecular_function	-	ND	Function
GO:0005575	cellular_component	-	ND	Component
GO:0007155	cell adhesion	-	IEA	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0008150	biological_process	-	ND	Process
GO:0008360	regulation of cell shape	-	IEA	Process
GO:0042127	regulation of cell proliferation	-	IEA	Process
GO:2000270	negative regulation of fibroblast apoptotic process	-	IEA	Process