EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000155275 (Gene tree)
Gene ID: 152992
Gene Symbol: TRMT44
Alias: FLJ35725|TRM44|C4orf23|METTL19
Full Name: tRNA methyltransferase 44 homolog
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 80,408 bases
Position: chr4:8,436,140-8,516,547
Accession: 26653
RBP type: canonical RBP
Summary: The protein encoded by this gene is a putative tRNA methyltransferase found in the cytoplasm. Defects in this gene may be a cause of partial epilepsy with pericentral spikes (PEPS), but that has not been proven definitively. [provided by RefSeq, May 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000424643	AdoMet_MTase	PF07757.13	1.9e-40	1	1
ENSP00000374387	AdoMet_MTase	PF07757.13	4.1e-40	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000389737	TRMT44-201	2799	XM_011513406	ENSP00000374387	757 (aa)	XP_011511708	Q8IYL2
ENST00000504134	TRMT44-202	660	-	ENSP00000434207	220 (aa)	-	H0YDS2
ENST00000531038	TRMT44-207	541	-	-	- (aa)	-	-
ENST00000528167	TRMT44-206	775	-	-	- (aa)	-	-
ENST00000532937	TRMT44-209	770	-	-	- (aa)	-	-
ENST00000511366	TRMT44-204	4157	-	-	- (aa)	-	-
ENST00000513449	TRMT44-205	1666	-	ENSP00000424643	411 (aa)	-	Q8IYL2
ENST00000532477	TRMT44-208	1851	-	-	- (aa)	-	-
ENST00000511149	TRMT44-203	508	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000155275's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000155275	Body Height	8.3543782868123E-5	17903300
ENSG00000155275	Body Height	5.05650024282822E-5	17903300
ENSG00000155275	Hip	1.36738383522661E-11	17903296
ENSG00000155275	Hip	6.16024248603849E-9	17903296
ENSG00000155275	Blood Pressure	7.9820000E-005	-
ENSG00000155275	Antineoplastic Agents	8E-7	21659360

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000155275	rs2631738	4	8478027	G	Blood protein levels	29875488	[0.15-0.23] unit increase	0.19	EFO_0007937
ENSG00000155275	rs2688220	4	8482686	C	Blood protein levels	30072576	[0.092-0.19] unit increase	0.141	EFO_0007937

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000155275's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000155275	TRMT44	97	60.750	ENSAPOG00000011969	trmt44	88	55.518	Acanthochromis_polyacanthus
ENSG00000155275	TRMT44	98	76.559	ENSAMEG00000014919	TRMT44	99	70.277	Ailuropoda_melanoleuca
ENSG00000155275	TRMT44	96	61.929	ENSAOCG00000003919	trmt44	89	56.093	Amphiprion_ocellaris
ENSG00000155275	TRMT44	96	61.929	ENSAPEG00000014205	trmt44	89	56.093	Amphiprion_percula
ENSG00000155275	TRMT44	63	76.357	ENSACAG00000012152	-	100	70.359	Anolis_carolinensis
ENSG00000155275	TRMT44	99	87.831	ENSANAG00000026046	TRMT44	99	87.831	Aotus_nancymaae
ENSG00000155275	TRMT44	96	61.832	ENSACLG00000004142	trmt44	95	56.333	Astatotilapia_calliptera
ENSG00000155275	TRMT44	97	60.697	ENSAMXG00000011302	trmt44	90	55.719	Astyanax_mexicanus
ENSG00000155275	TRMT44	98	76.060	ENSBTAG00000004797	TRMT44	99	71.373	Bos_taurus
ENSG00000155275	TRMT44	57	40.000	WBGene00016014	C23G10.7	69	40.000	Caenorhabditis_elegans
ENSG00000155275	TRMT44	99	78.864	ENSCJAG00000021498	TRMT44	100	78.864	Callithrix_jacchus
ENSG00000155275	TRMT44	98	73.632	ENSCAFG00000014566	TRMT44	99	75.204	Canis_familiaris
ENSG00000155275	TRMT44	98	73.632	ENSCAFG00020014653	TRMT44	99	68.504	Canis_lupus_dingo
ENSG00000155275	TRMT44	98	72.637	ENSCHIG00000019204	TRMT44	99	69.922	Capra_hircus
ENSG00000155275	TRMT44	98	80.893	ENSTSYG00000026681	-	99	80.893	Carlito_syrichta
ENSG00000155275	TRMT44	98	70.896	ENSCAPG00000005185	TRMT44	99	71.585	Cavia_aperea
ENSG00000155275	TRMT44	98	70.647	ENSCPOG00000032399	TRMT44	99	66.125	Cavia_porcellus
ENSG00000155275	TRMT44	99	87.135	ENSCCAG00000018176	TRMT44	98	88.265	Cebus_capucinus
ENSG00000155275	TRMT44	99	87.368	ENSCATG00000035762	TRMT44	99	87.368	Cercocebus_atys
ENSG00000155275	TRMT44	98	73.067	ENSCLAG00000008063	TRMT44	92	71.166	Chinchilla_lanigera
ENSG00000155275	TRMT44	99	94.321	ENSCSAG00000015971	TRMT44	99	93.542	Chlorocebus_sabaeus
ENSG00000155275	TRMT44	97	63.476	ENSCHOG00000004165	TRMT44	100	65.116	Choloepus_hoffmanni
ENSG00000155275	TRMT44	97	65.500	ENSCPBG00000025042	TRMT44	99	57.784	Chrysemys_picta_bellii
ENSG00000155275	TRMT44	92	44.531	ENSCING00000011437	-	88	45.417	Ciona_intestinalis
ENSG00000155275	TRMT44	51	43.041	ENSCSAVG00000002267	-	98	42.010	Ciona_savignyi
ENSG00000155275	TRMT44	95	93.349	ENSCANG00000024116	TRMT44	99	93.349	Colobus_angolensis_palliatus
ENSG00000155275	TRMT44	98	75.312	ENSCGRG00001016915	Trmt44	99	66.013	Cricetulus_griseus_chok1gshd
ENSG00000155275	TRMT44	98	75.312	ENSCGRG00000012909	Trmt44	93	65.752	Cricetulus_griseus_crigri
ENSG00000155275	TRMT44	95	61.125	ENSCSEG00000002544	trmt44	88	54.516	Cynoglossus_semilaevis
ENSG00000155275	TRMT44	84	71.429	ENSCVAG00000007403	trmt44	96	71.429	Cyprinodon_variegatus
ENSG00000155275	TRMT44	95	60.969	ENSDARG00000033957	trmt44	91	54.439	Danio_rerio
ENSG00000155275	TRMT44	98	73.086	ENSDNOG00000003636	TRMT44	99	70.104	Dasypus_novemcinctus
ENSG00000155275	TRMT44	98	68.889	ENSDORG00000006411	Trmt44	99	69.082	Dipodomys_ordii
ENSG00000155275	TRMT44	58	45.344	FBgn0037708	CG9386	71	45.344	Drosophila_melanogaster
ENSG00000155275	TRMT44	98	77.805	ENSEASG00005004478	TRMT44	98	73.797	Equus_asinus_asinus
ENSG00000155275	TRMT44	98	77.057	ENSECAG00000011958	TRMT44	96	73.138	Equus_caballus
ENSG00000155275	TRMT44	96	59.288	ENSELUG00000014827	trmt44	89	52.805	Esox_lucius
ENSG00000155275	TRMT44	98	73.945	ENSFCAG00000015295	TRMT44	100	73.945	Felis_catus
ENSG00000155275	TRMT44	97	66.500	ENSFALG00000009686	TRMT44	99	64.821	Ficedula_albicollis
ENSG00000155275	TRMT44	98	70.574	ENSFDAG00000018173	TRMT44	99	66.931	Fukomys_damarensis
ENSG00000155275	TRMT44	85	76.923	ENSFHEG00000001865	trmt44	96	76.923	Fundulus_heteroclitus
ENSG00000155275	TRMT44	66	65.314	ENSGMOG00000007872	trmt44	88	56.300	Gadus_morhua
ENSG00000155275	TRMT44	97	65.250	ENSGALG00000015594	TRMT44	99	60.000	Gallus_gallus
ENSG00000155275	TRMT44	87	73.077	ENSGAFG00000005638	trmt44	93	52.582	Gambusia_affinis
ENSG00000155275	TRMT44	96	59.542	ENSGACG00000019409	trmt44	94	57.143	Gasterosteus_aculeatus
ENSG00000155275	TRMT44	97	64.750	ENSGAGG00000005306	TRMT44	87	62.319	Gopherus_agassizii
ENSG00000155275	TRMT44	100	98.018	ENSGGOG00000008016	TRMT44	100	98.018	Gorilla_gorilla
ENSG00000155275	TRMT44	96	61.832	ENSHBUG00000002520	trmt44	95	56.333	Haplochromis_burtoni
ENSG00000155275	TRMT44	98	69.327	ENSHGLG00000014808	TRMT44	99	75.000	Heterocephalus_glaber_female
ENSG00000155275	TRMT44	96	56.456	ENSHCOG00000013392	trmt44	88	52.034	Hippocampus_comes
ENSG00000155275	TRMT44	90	63.315	ENSIPUG00000019663	trmt44	92	54.886	Ictalurus_punctatus
ENSG00000155275	TRMT44	98	76.179	ENSSTOG00000014057	TRMT44	99	74.554	Ictidomys_tridecemlineatus
ENSG00000155275	TRMT44	98	75.810	ENSJJAG00000018255	Trmt44	99	75.890	Jaculus_jaculus
ENSG00000155275	TRMT44	95	61.480	ENSLBEG00000026158	trmt44	89	55.907	Labrus_bergylta
ENSG00000155275	TRMT44	96	65.404	ENSLACG00000007065	TRMT44	87	60.269	Latimeria_chalumnae
ENSG00000155275	TRMT44	97	62.745	ENSLOCG00000010316	trmt44	89	55.854	Lepisosteus_oculatus
ENSG00000155275	TRMT44	98	73.020	ENSLAFG00000005046	TRMT44	99	67.457	Loxodonta_africana
ENSG00000155275	TRMT44	99	93.254	ENSMFAG00000025459	TRMT44	88	93.254	Macaca_fascicularis
ENSG00000155275	TRMT44	99	92.989	ENSMNEG00000030113	TRMT44	88	92.989	Macaca_nemestrina
ENSG00000155275	TRMT44	97	92.695	ENSMLEG00000038987	TRMT44	99	88.095	Mandrillus_leucophaeus
ENSG00000155275	TRMT44	96	60.859	ENSMAMG00000003804	trmt44	97	55.556	Mastacembelus_armatus
ENSG00000155275	TRMT44	96	61.832	ENSMZEG00005021775	trmt44	95	56.333	Maylandia_zebra
ENSG00000155275	TRMT44	98	75.561	ENSMAUG00000021974	Trmt44	99	66.580	Mesocricetus_auratus
ENSG00000155275	TRMT44	98	82.587	ENSMICG00000032294	-	98	84.383	Microcebus_murinus
ENSG00000155275	TRMT44	98	74.314	ENSMOCG00000017807	Trmt44	99	66.798	Microtus_ochrogaster
ENSG00000155275	TRMT44	91	69.600	ENSMODG00000003166	TRMT44	99	58.553	Monodelphis_domestica
ENSG00000155275	TRMT44	96	59.596	ENSMALG00000010274	trmt44	90	54.711	Monopterus_albus
ENSG00000155275	TRMT44	98	74.314	MGP_CAROLIEiJ_G0027148	Trmt44	99	65.298	Mus_caroli
ENSG00000155275	TRMT44	98	74.813	ENSMUSG00000029097	Trmt44	99	66.093	Mus_musculus
ENSG00000155275	TRMT44	98	75.062	MGP_PahariEiJ_G0016932	Trmt44	99	66.358	Mus_pahari
ENSG00000155275	TRMT44	98	74.813	MGP_SPRETEiJ_G0028144	Trmt44	99	65.828	Mus_spretus
ENSG00000155275	TRMT44	98	76.559	ENSMPUG00000010536	TRMT44	99	70.171	Mustela_putorius_furo
ENSG00000155275	TRMT44	98	71.220	ENSMLUG00000007497	TRMT44	100	71.547	Myotis_lucifugus
ENSG00000155275	TRMT44	98	74.314	ENSNGAG00000000623	Trmt44	99	65.828	Nannospalax_galili
ENSG00000155275	TRMT44	98	94.045	ENSNLEG00000011922	TRMT44	99	91.029	Nomascus_leucogenys
ENSG00000155275	TRMT44	74	58.571	ENSMEUG00000011235	-	82	64.194	Notamacropus_eugenii
ENSG00000155275	TRMT44	97	60.957	ENSOPRG00000015801	TRMT44	99	59.709	Ochotona_princeps
ENSG00000155275	TRMT44	97	65.500	ENSODEG00000009730	TRMT44	99	62.351	Octodon_degus
ENSG00000155275	TRMT44	96	61.323	ENSONIG00000001822	trmt44	95	56.240	Oreochromis_niloticus
ENSG00000155275	TRMT44	96	61.055	ENSORLG00000006105	trmt44	85	56.326	Oryzias_latipes
ENSG00000155275	TRMT44	96	60.606	ENSORLG00020010648	trmt44	85	56.000	Oryzias_latipes_hni
ENSG00000155275	TRMT44	95	61.538	ENSORLG00015007583	trmt44	85	56.174	Oryzias_latipes_hsok
ENSG00000155275	TRMT44	95	61.282	ENSOMEG00000010152	trmt44	94	55.556	Oryzias_melastigma
ENSG00000155275	TRMT44	98	78.803	ENSOGAG00000002246	TRMT44	99	73.377	Otolemur_garnettii
ENSG00000155275	TRMT44	98	68.642	ENSOARG00000013130	TRMT44	99	63.158	Ovis_aries
ENSG00000155275	TRMT44	98	96.509	ENSPPAG00000028201	TRMT44	84	95.098	Pan_paniscus
ENSG00000155275	TRMT44	98	72.818	ENSPPRG00000001613	TRMT44	98	74.307	Panthera_pardus
ENSG00000155275	TRMT44	98	69.554	ENSPTIG00000013080	-	98	72.544	Panthera_tigris_altaica
ENSG00000155275	TRMT44	100	98.679	ENSPTRG00000034388	TRMT44	100	98.679	Pan_troglodytes
ENSG00000155275	TRMT44	99	92.328	ENSPANG00000006054	TRMT44	99	92.328	Papio_anubis
ENSG00000155275	TRMT44	95	58.718	ENSPKIG00000004663	trmt44	83	55.026	Paramormyrops_kingsleyae
ENSG00000155275	TRMT44	97	66.500	ENSPSIG00000014471	TRMT44	98	62.701	Pelodiscus_sinensis
ENSG00000155275	TRMT44	98	75.810	ENSPEMG00000007598	Trmt44	98	68.470	Peromyscus_maniculatus_bairdii
ENSG00000155275	TRMT44	97	56.968	ENSPMAG00000006935	trmt44	87	51.329	Petromyzon_marinus
ENSG00000155275	TRMT44	97	71.571	ENSPCIG00000023633	TRMT44	93	60.841	Phascolarctos_cinereus
ENSG00000155275	TRMT44	87	73.077	ENSPFOG00000006276	trmt44	93	53.208	Poecilia_formosa
ENSG00000155275	TRMT44	87	73.077	ENSPLAG00000009548	trmt44	93	52.895	Poecilia_latipinna
ENSG00000155275	TRMT44	87	73.077	ENSPMEG00000000021	trmt44	93	53.365	Poecilia_mexicana
ENSG00000155275	TRMT44	87	73.077	ENSPREG00000013993	trmt44	74	73.077	Poecilia_reticulata
ENSG00000155275	TRMT44	97	65.075	ENSPCAG00000016248	TRMT44	100	59.284	Procavia_capensis
ENSG00000155275	TRMT44	98	83.042	ENSPCOG00000028809	TRMT44	98	79.392	Propithecus_coquereli
ENSG00000155275	TRMT44	97	66.750	ENSPVAG00000006361	TRMT44	100	66.924	Pteropus_vampyrus
ENSG00000155275	TRMT44	97	61.153	ENSPNYG00000006472	trmt44	95	56.333	Pundamilia_nyererei
ENSG00000155275	TRMT44	89	62.670	ENSPNAG00000017390	trmt44	94	54.295	Pygocentrus_nattereri
ENSG00000155275	TRMT44	98	75.682	ENSRNOG00000008898	Trmt44	98	66.446	Rattus_norvegicus
ENSG00000155275	TRMT44	99	93.254	ENSRBIG00000027415	TRMT44	99	93.254	Rhinopithecus_bieti
ENSG00000155275	TRMT44	99	93.386	ENSRROG00000031428	TRMT44	99	93.386	Rhinopithecus_roxellana
ENSG00000155275	TRMT44	98	85.037	ENSSBOG00000025156	TRMT44	99	81.759	Saimiri_boliviensis_boliviensis
ENSG00000155275	TRMT44	98	70.398	ENSSHAG00000016610	TRMT44	98	61.252	Sarcophilus_harrisii
ENSG00000155275	TRMT44	97	59.148	ENSSFOG00015017345	trmt44	80	55.830	Scleropages_formosus
ENSG00000155275	TRMT44	96	60.305	ENSSMAG00000009566	trmt44	94	57.895	Scophthalmus_maximus
ENSG00000155275	TRMT44	95	61.929	ENSSDUG00000020112	trmt44	97	56.230	Seriola_dumerili
ENSG00000155275	TRMT44	95	61.421	ENSSLDG00000012354	trmt44	97	55.574	Seriola_lalandi_dorsalis
ENSG00000155275	TRMT44	92	68.254	ENSSPUG00000002536	TRMT44	97	65.854	Sphenodon_punctatus
ENSG00000155275	TRMT44	96	61.929	ENSSPAG00000016281	trmt44	89	56.260	Stegastes_partitus
ENSG00000155275	TRMT44	98	65.025	ENSSSCG00000033873	TRMT44	92	64.675	Sus_scrofa
ENSG00000155275	TRMT44	97	65.025	ENSTGUG00000010279	-	99	64.632	Taeniopygia_guttata
ENSG00000155275	TRMT44	96	59.796	ENSTRUG00000011090	trmt44	89	54.063	Takifugu_rubripes
ENSG00000155275	TRMT44	95	59.591	ENSTNIG00000010146	trmt44	98	54.237	Tetraodon_nigroviridis
ENSG00000155275	TRMT44	97	69.270	ENSTBEG00000006893	TRMT44	99	67.063	Tupaia_belangeri
ENSG00000155275	TRMT44	99	70.331	ENSTTRG00000014379	TRMT44	99	70.331	Tursiops_truncatus
ENSG00000155275	TRMT44	98	75.062	ENSUAMG00000011767	TRMT44	99	72.632	Ursus_americanus
ENSG00000155275	TRMT44	98	74.505	ENSUMAG00000009816	TRMT44	99	77.472	Ursus_maritimus
ENSG00000155275	TRMT44	98	73.632	ENSVVUG00000025044	TRMT44	99	69.312	Vulpes_vulpes
ENSG00000155275	TRMT44	97	57.107	ENSXETG00000030882	TRMT44	88	68.605	Xenopus_tropicalis
ENSG00000155275	TRMT44	94	60.567	ENSXCOG00000002360	trmt44	95	73.077	Xiphophorus_couchianus
ENSG00000155275	TRMT44	87	73.077	ENSXMAG00000015817	trmt44	93	52.830	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005737	cytoplasm	-	IEA	Component
GO:0016300	tRNA (uracil) methyltransferase activity	21873635.	IBA	Function
GO:0030488	tRNA methylation	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function