EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000156239 (Gene tree)
Gene ID: 29104
Gene Symbol: N6AMT1
Alias: PRED28|N6AMT|MTQ2|C21orf127|HEMK2
Full Name: N-6 adenine-specific DNA methyltransferase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 13,183 bases
Position: chr21:28,872,191-28,885,373
Accession: 16021
RBP type: canonical RBP
Summary: This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jul 2014]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000303584	MTS	PF05175.14	8.5e-10	1	1
ENSP00000286764	MTS	PF05175.14	9e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000303775	N6AMT1-201	4865	-	ENSP00000303584	214 (aa)	-	Q9Y5N5
ENST00000460212	N6AMT1-203	1293	-	ENSP00000436490	214 (aa)	-	Q9Y5N5
ENST00000351429	N6AMT1-202	4781	-	ENSP00000286764	186 (aa)	-	Q9Y5N5

Gene Model

Click here to download ENSG00000156239's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000156239's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000156239	N6AMT1	99	63.850	ENSAPOG00000009868	n6amt1	98	63.850	Acanthochromis_polyacanthus
ENSG00000156239	N6AMT1	100	90.654	ENSAMEG00000008279	N6AMT1	100	90.654	Ailuropoda_melanoleuca
ENSG00000156239	N6AMT1	97	64.115	ENSACIG00000017021	n6amt1	96	64.115	Amphilophus_citrinellus
ENSG00000156239	N6AMT1	98	52.830	ENSAOCG00000002525	n6amt1	97	52.830	Amphiprion_ocellaris
ENSG00000156239	N6AMT1	98	63.679	ENSAPEG00000015144	n6amt1	97	63.679	Amphiprion_percula
ENSG00000156239	N6AMT1	98	67.943	ENSATEG00000017766	n6amt1	88	67.943	Anabas_testudineus
ENSG00000156239	N6AMT1	79	76.786	ENSAPLG00000003868	N6AMT1	99	76.786	Anas_platyrhynchos
ENSG00000156239	N6AMT1	92	62.312	ENSACAG00000001341	N6AMT1	79	70.000	Anolis_carolinensis
ENSG00000156239	N6AMT1	100	75.225	ENSANAG00000032017	N6AMT1	100	75.225	Aotus_nancymaae
ENSG00000156239	N6AMT1	70	81.208	ENSANAG00000024312	-	93	81.208	Aotus_nancymaae
ENSG00000156239	N6AMT1	98	63.208	ENSACLG00000024678	n6amt1	84	63.208	Astatotilapia_calliptera
ENSG00000156239	N6AMT1	98	68.246	ENSAMXG00000029868	n6amt1	98	68.246	Astyanax_mexicanus
ENSG00000156239	N6AMT1	100	90.654	ENSBTAG00000001412	N6AMT1	82	90.654	Bos_taurus
ENSG00000156239	N6AMT1	89	47.150	WBGene00016341	mtq-2	86	47.150	Caenorhabditis_elegans
ENSG00000156239	N6AMT1	100	91.935	ENSCJAG00000047026	N6AMT1	100	91.935	Callithrix_jacchus
ENSG00000156239	N6AMT1	63	94.030	ENSCAFG00000030996	N6AMT1	57	94.030	Canis_familiaris
ENSG00000156239	N6AMT1	100	89.720	ENSCAFG00020026293	N6AMT1	100	89.720	Canis_lupus_dingo
ENSG00000156239	N6AMT1	100	91.589	ENSCHIG00000016325	N6AMT1	100	91.589	Capra_hircus
ENSG00000156239	N6AMT1	100	89.252	ENSTSYG00000004325	N6AMT1	100	89.252	Carlito_syrichta
ENSG00000156239	N6AMT1	100	91.121	ENSCPOG00000030645	N6AMT1	100	91.121	Cavia_porcellus
ENSG00000156239	N6AMT1	100	94.086	ENSCCAG00000033809	N6AMT1	100	94.086	Cebus_capucinus
ENSG00000156239	N6AMT1	83	81.356	ENSCATG00000030066	-	100	81.356	Cercocebus_atys
ENSG00000156239	N6AMT1	99	91.080	ENSCLAG00000009758	N6AMT1	97	91.080	Chinchilla_lanigera
ENSG00000156239	N6AMT1	99	85.514	ENSCSAG00000003461	-	99	85.514	Chlorocebus_sabaeus
ENSG00000156239	N6AMT1	100	95.794	ENSCSAG00000009113	N6AMT1	100	95.794	Chlorocebus_sabaeus
ENSG00000156239	N6AMT1	100	89.720	ENSCHOG00000005227	N6AMT1	100	89.720	Choloepus_hoffmanni
ENSG00000156239	N6AMT1	79	79.290	ENSCPBG00000006708	N6AMT1	96	79.290	Chrysemys_picta_bellii
ENSG00000156239	N6AMT1	96	54.327	ENSCSAVG00000002533	-	93	54.327	Ciona_savignyi
ENSG00000156239	N6AMT1	99	77.465	ENSCANG00000034907	-	99	76.995	Colobus_angolensis_palliatus
ENSG00000156239	N6AMT1	100	87.383	ENSCGRG00001012196	N6amt1	100	87.383	Cricetulus_griseus_chok1gshd
ENSG00000156239	N6AMT1	100	86.449	ENSCGRG00000014832	N6amt1	100	86.449	Cricetulus_griseus_crigri
ENSG00000156239	N6AMT1	98	64.455	ENSCSEG00000004007	n6amt1	97	64.455	Cynoglossus_semilaevis
ENSG00000156239	N6AMT1	98	65.566	ENSCVAG00000015389	n6amt1	94	65.566	Cyprinodon_variegatus
ENSG00000156239	N6AMT1	98	62.085	ENSDARG00000115421	n6amt1	96	62.085	Danio_rerio
ENSG00000156239	N6AMT1	100	90.187	ENSDNOG00000002069	N6AMT1	100	90.187	Dasypus_novemcinctus
ENSG00000156239	N6AMT1	100	88.318	ENSDORG00000028667	N6amt1	100	88.318	Dipodomys_ordii
ENSG00000156239	N6AMT1	96	39.091	FBgn0031454	CG9960	97	39.091	Drosophila_melanogaster
ENSG00000156239	N6AMT1	99	65.728	ENSETEG00000017725	N6AMT1	99	65.728	Echinops_telfairi
ENSG00000156239	N6AMT1	94	53.695	ENSEBUG00000007863	n6amt1	91	53.695	Eptatretus_burgeri
ENSG00000156239	N6AMT1	100	92.056	ENSEASG00005008146	N6AMT1	91	92.056	Equus_asinus_asinus
ENSG00000156239	N6AMT1	100	92.056	ENSECAG00000009080	N6AMT1	93	92.000	Equus_caballus
ENSG00000156239	N6AMT1	99	87.324	ENSEEUG00000013787	N6AMT1	99	87.324	Erinaceus_europaeus
ENSG00000156239	N6AMT1	98	67.773	ENSELUG00000001748	n6amt1	99	67.773	Esox_lucius
ENSG00000156239	N6AMT1	99	90.610	ENSFCAG00000013161	N6AMT1	98	90.610	Felis_catus
ENSG00000156239	N6AMT1	97	75.829	ENSFALG00000001717	N6AMT1	98	75.355	Ficedula_albicollis
ENSG00000156239	N6AMT1	99	89.671	ENSFDAG00000012916	-	99	89.671	Fukomys_damarensis
ENSG00000156239	N6AMT1	98	65.877	ENSFHEG00000018883	n6amt1	97	65.877	Fundulus_heteroclitus
ENSG00000156239	N6AMT1	80	68.391	ENSGMOG00000000902	n6amt1	100	68.391	Gadus_morhua
ENSG00000156239	N6AMT1	99	73.148	ENSGALG00000015802	N6AMT1	99	70.370	Gallus_gallus
ENSG00000156239	N6AMT1	88	65.789	ENSGAFG00000019817	n6amt1	99	65.789	Gambusia_affinis
ENSG00000156239	N6AMT1	97	65.550	ENSGACG00000014248	n6amt1	99	63.158	Gasterosteus_aculeatus
ENSG00000156239	N6AMT1	97	78.095	ENSGAGG00000024117	N6AMT1	83	75.238	Gopherus_agassizii
ENSG00000156239	N6AMT1	97	80.193	ENSGGOG00000008382	-	96	80.193	Gorilla_gorilla
ENSG00000156239	N6AMT1	100	99.065	ENSGGOG00000022382	N6AMT1	100	99.065	Gorilla_gorilla
ENSG00000156239	N6AMT1	100	63.551	ENSHBUG00000002644	n6amt1	99	63.551	Haplochromis_burtoni
ENSG00000156239	N6AMT1	99	91.080	ENSHGLG00000016904	N6AMT1	99	91.080	Heterocephalus_glaber_female
ENSG00000156239	N6AMT1	99	91.080	ENSHGLG00100008400	N6AMT1	99	91.080	Heterocephalus_glaber_male
ENSG00000156239	N6AMT1	97	63.158	ENSHCOG00000006177	n6amt1	96	63.158	Hippocampus_comes
ENSG00000156239	N6AMT1	98	64.929	ENSIPUG00000009452	n6amt1	88	64.929	Ictalurus_punctatus
ENSG00000156239	N6AMT1	100	87.850	ENSSTOG00000021743	N6AMT1	100	87.850	Ictidomys_tridecemlineatus
ENSG00000156239	N6AMT1	100	89.720	ENSJJAG00000001593	N6amt1	100	89.720	Jaculus_jaculus
ENSG00000156239	N6AMT1	98	63.333	ENSKMAG00000000880	n6amt1	98	63.333	Kryptolebias_marmoratus
ENSG00000156239	N6AMT1	98	65.877	ENSLBEG00000027051	n6amt1	98	65.877	Labrus_bergylta
ENSG00000156239	N6AMT1	96	70.874	ENSLACG00000006042	N6AMT1	95	70.874	Latimeria_chalumnae
ENSG00000156239	N6AMT1	97	66.507	ENSLOCG00000010815	n6amt1	98	66.507	Lepisosteus_oculatus
ENSG00000156239	N6AMT1	100	90.654	ENSLAFG00000001451	N6AMT1	100	90.654	Loxodonta_africana
ENSG00000156239	N6AMT1	99	78.873	ENSMFAG00000030722	-	99	78.873	Macaca_fascicularis
ENSG00000156239	N6AMT1	100	96.774	ENSMFAG00000032851	N6AMT1	100	96.774	Macaca_fascicularis
ENSG00000156239	N6AMT1	99	77.934	ENSMMUG00000044515	-	99	77.934	Macaca_mulatta
ENSG00000156239	N6AMT1	100	96.237	ENSMMUG00000015726	N6AMT1	100	96.237	Macaca_mulatta
ENSG00000156239	N6AMT1	99	78.873	ENSMNEG00000042890	-	99	78.873	Macaca_nemestrina
ENSG00000156239	N6AMT1	100	96.774	ENSMNEG00000031541	N6AMT1	100	96.774	Macaca_nemestrina
ENSG00000156239	N6AMT1	100	96.774	ENSMLEG00000034650	N6AMT1	100	96.774	Mandrillus_leucophaeus
ENSG00000156239	N6AMT1	98	62.085	ENSMAMG00000022339	n6amt1	98	58.768	Mastacembelus_armatus
ENSG00000156239	N6AMT1	100	63.551	ENSMZEG00005017792	n6amt1	99	63.551	Maylandia_zebra
ENSG00000156239	N6AMT1	99	73.364	ENSMGAG00000014501	N6AMT1	99	73.364	Meleagris_gallopavo
ENSG00000156239	N6AMT1	99	87.568	ENSMAUG00000007604	N6amt1	99	87.568	Mesocricetus_auratus
ENSG00000156239	N6AMT1	100	92.473	ENSMICG00000045182	N6AMT1	100	92.473	Microcebus_murinus
ENSG00000156239	N6AMT1	100	86.916	ENSMOCG00000001686	N6amt1	100	86.916	Microtus_ochrogaster
ENSG00000156239	N6AMT1	98	63.981	ENSMMOG00000010286	n6amt1	98	63.981	Mola_mola
ENSG00000156239	N6AMT1	60	67.188	ENSMMOG00000019494	-	86	64.844	Mola_mola
ENSG00000156239	N6AMT1	83	84.831	ENSMODG00000020997	N6AMT1	85	84.831	Monodelphis_domestica
ENSG00000156239	N6AMT1	98	61.792	ENSMALG00000016738	n6amt1	97	61.792	Monopterus_albus
ENSG00000156239	N6AMT1	100	88.318	MGP_CAROLIEiJ_G0020896	N6amt1	100	88.318	Mus_caroli
ENSG00000156239	N6AMT1	100	87.383	ENSMUSG00000044442	N6amt1	99	88.827	Mus_musculus
ENSG00000156239	N6AMT1	100	88.785	MGP_PahariEiJ_G0016600	N6amt1	100	88.785	Mus_pahari
ENSG00000156239	N6AMT1	100	88.318	MGP_SPRETEiJ_G0021802	N6amt1	99	89.944	Mus_spretus
ENSG00000156239	N6AMT1	100	89.720	ENSMPUG00000001030	N6AMT1	100	89.720	Mustela_putorius_furo
ENSG00000156239	N6AMT1	100	86.916	ENSMLUG00000016771	N6AMT1	100	86.916	Myotis_lucifugus
ENSG00000156239	N6AMT1	99	87.793	ENSNGAG00000018091	N6amt1	97	87.793	Nannospalax_galili
ENSG00000156239	N6AMT1	98	63.208	ENSNBRG00000003897	n6amt1	97	63.208	Neolamprologus_brichardi
ENSG00000156239	N6AMT1	100	98.387	ENSNLEG00000002845	N6AMT1	100	98.387	Nomascus_leucogenys
ENSG00000156239	N6AMT1	97	82.609	ENSMEUG00000008047	N6AMT1	97	82.609	Notamacropus_eugenii
ENSG00000156239	N6AMT1	100	85.514	ENSOPRG00000001551	N6AMT1	100	85.514	Ochotona_princeps
ENSG00000156239	N6AMT1	79	89.286	ENSODEG00000002664	N6AMT1	93	89.286	Octodon_degus
ENSG00000156239	N6AMT1	98	62.264	ENSONIG00000001882	n6amt1	97	62.264	Oreochromis_niloticus
ENSG00000156239	N6AMT1	100	88.318	ENSOCUG00000001084	N6AMT1	100	88.318	Oryctolagus_cuniculus
ENSG00000156239	N6AMT1	98	62.085	ENSORLG00000005038	n6amt1	97	62.085	Oryzias_latipes
ENSG00000156239	N6AMT1	98	61.611	ENSORLG00020017088	n6amt1	97	61.611	Oryzias_latipes_hni
ENSG00000156239	N6AMT1	98	61.611	ENSORLG00015015298	n6amt1	92	61.611	Oryzias_latipes_hsok
ENSG00000156239	N6AMT1	98	62.559	ENSOMEG00000006621	n6amt1	97	60.190	Oryzias_melastigma
ENSG00000156239	N6AMT1	100	82.243	ENSOGAG00000011265	N6AMT1	100	82.243	Otolemur_garnettii
ENSG00000156239	N6AMT1	100	91.589	ENSOARG00000014732	N6AMT1	93	91.589	Ovis_aries
ENSG00000156239	N6AMT1	100	98.131	ENSPPAG00000034453	N6AMT1	100	98.131	Pan_paniscus
ENSG00000156239	N6AMT1	97	83.575	ENSPPAG00000000088	-	98	83.575	Pan_paniscus
ENSG00000156239	N6AMT1	99	90.610	ENSPPRG00000023712	N6AMT1	98	90.610	Panthera_pardus
ENSG00000156239	N6AMT1	99	91.080	ENSPTIG00000020361	N6AMT1	98	91.080	Panthera_tigris_altaica
ENSG00000156239	N6AMT1	97	83.092	ENSPTRG00000048746	-	98	83.092	Pan_troglodytes
ENSG00000156239	N6AMT1	100	98.131	ENSPTRG00000013817	N6AMT1	100	98.131	Pan_troglodytes
ENSG00000156239	N6AMT1	96	66.827	ENSPKIG00000010822	n6amt1	98	66.827	Paramormyrops_kingsleyae
ENSG00000156239	N6AMT1	97	65.072	ENSPMGG00000023630	n6amt1	96	62.679	Periophthalmus_magnuspinnatus
ENSG00000156239	N6AMT1	100	85.981	ENSPEMG00000021354	N6amt1	100	85.981	Peromyscus_maniculatus_bairdii
ENSG00000156239	N6AMT1	98	82.297	ENSPCIG00000014183	N6AMT1	95	82.297	Phascolarctos_cinereus
ENSG00000156239	N6AMT1	98	65.094	ENSPFOG00000002291	n6amt1	97	65.094	Poecilia_formosa
ENSG00000156239	N6AMT1	98	65.094	ENSPLAG00000002780	n6amt1	97	65.094	Poecilia_latipinna
ENSG00000156239	N6AMT1	98	65.094	ENSPMEG00000015678	n6amt1	97	65.094	Poecilia_mexicana
ENSG00000156239	N6AMT1	98	64.151	ENSPREG00000006451	n6amt1	97	64.151	Poecilia_reticulata
ENSG00000156239	N6AMT1	100	97.196	ENSPPYG00000011314	N6AMT1	100	97.196	Pongo_abelii
ENSG00000156239	N6AMT1	100	92.473	ENSPCOG00000027720	N6AMT1	100	92.473	Propithecus_coquereli
ENSG00000156239	N6AMT1	79	64.118	ENSPVAG00000012777	N6AMT1	100	64.118	Pteropus_vampyrus
ENSG00000156239	N6AMT1	100	63.551	ENSPNYG00000022936	n6amt1	99	63.551	Pundamilia_nyererei
ENSG00000156239	N6AMT1	98	66.986	ENSPNAG00000010171	n6amt1	98	66.986	Pygocentrus_nattereri
ENSG00000156239	N6AMT1	100	88.785	ENSRNOG00000001603	N6amt1	100	88.785	Rattus_norvegicus
ENSG00000156239	N6AMT1	99	81.221	ENSRBIG00000042168	-	99	81.221	Rhinopithecus_bieti
ENSG00000156239	N6AMT1	99	81.081	ENSRBIG00000034221	-	99	81.081	Rhinopithecus_bieti
ENSG00000156239	N6AMT1	100	95.161	ENSRBIG00000026227	N6AMT1	100	95.161	Rhinopithecus_bieti
ENSG00000156239	N6AMT1	99	75.587	ENSRROG00000043758	-	99	75.587	Rhinopithecus_roxellana
ENSG00000156239	N6AMT1	100	96.237	ENSRROG00000027843	N6AMT1	100	96.237	Rhinopithecus_roxellana
ENSG00000156239	N6AMT1	91	34.579	YDR140W	-	95	34.579	Saccharomyces_cerevisiae
ENSG00000156239	N6AMT1	100	94.624	ENSSBOG00000011411	N6AMT1	100	94.624	Saimiri_boliviensis_boliviensis
ENSG00000156239	N6AMT1	97	65.714	ENSSFOG00015009049	n6amt1	99	65.714	Scleropages_formosus
ENSG00000156239	N6AMT1	97	65.072	ENSSMAG00000015250	n6amt1	96	65.072	Scophthalmus_maximus
ENSG00000156239	N6AMT1	98	65.403	ENSSDUG00000005324	n6amt1	97	65.403	Seriola_dumerili
ENSG00000156239	N6AMT1	98	65.403	ENSSLDG00000013280	n6amt1	97	65.403	Seriola_lalandi_dorsalis
ENSG00000156239	N6AMT1	96	75.362	ENSSPUG00000011186	N6AMT1	96	74.879	Sphenodon_punctatus
ENSG00000156239	N6AMT1	98	63.208	ENSSPAG00000005551	n6amt1	97	63.208	Stegastes_partitus
ENSG00000156239	N6AMT1	100	88.785	ENSSSCG00000028724	-	97	88.785	Sus_scrofa
ENSG00000156239	N6AMT1	99	72.811	ENSTGUG00000013486	N6AMT1	100	72.811	Taeniopygia_guttata
ENSG00000156239	N6AMT1	97	66.298	ENSTRUG00000013586	n6amt1	98	66.298	Takifugu_rubripes
ENSG00000156239	N6AMT1	98	67.453	ENSTNIG00000008309	n6amt1	98	67.453	Tetraodon_nigroviridis
ENSG00000156239	N6AMT1	99	90.610	ENSTBEG00000001269	N6AMT1	99	90.610	Tupaia_belangeri
ENSG00000156239	N6AMT1	100	91.121	ENSUAMG00000012833	N6AMT1	100	91.121	Ursus_americanus
ENSG00000156239	N6AMT1	93	91.414	ENSUMAG00000014907	N6AMT1	90	91.414	Ursus_maritimus
ENSG00000156239	N6AMT1	100	89.767	ENSVPAG00000012406	N6AMT1	100	89.767	Vicugna_pacos
ENSG00000156239	N6AMT1	100	89.720	ENSVVUG00000009460	N6AMT1	100	89.720	Vulpes_vulpes
ENSG00000156239	N6AMT1	98	64.929	ENSXMAG00000002875	n6amt1	85	63.721	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0005515	protein binding	18539146.	IPI	Function
GO:0005634	nucleus	-	ISS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006415	translational termination	-	TAS	Process
GO:0008276	protein methyltransferase activity	21873635.	IBA	Function
GO:0008276	protein methyltransferase activity	18539146.	IDA	Function
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	21873635.	IBA	Function
GO:0009007	site-specific DNA-methyltransferase (adenine-specific) activity	30017583.	IDA	Function
GO:0009404	toxin metabolic process	25997655.	IDA	Process
GO:0018364	peptidyl-glutamine methylation	18539146.	IDA	Process
GO:0018872	arsonoacetate metabolic process	25997655.	IDA	Process
GO:0030307	positive regulation of cell growth	18539146.	IDA	Process
GO:0030792	methylarsonite methyltransferase activity	25997655.	IDA	Function
GO:0032259	methylation	25997655.	IDA	Process
GO:0032259	methylation	-	TAS	Process
GO:0032775	DNA methylation on adenine	30017583.	IDA	Process
GO:0032991	protein-containing complex	18539146.	IDA	Component
GO:0035657	eRF1 methyltransferase complex	21873635.	IBA	Component
GO:0036009	protein-glutamine N-methyltransferase activity	18539146.	IDA	Function