EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000156261 (Gene tree)
Gene ID: 10694
Gene Symbol: CCT8
Alias: Cctq|PRED71|C21orf112
Full Name: chaperonin containing TCP1 subunit 8
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 17,993 bases
Position: chr21:29,055,805-29,073,797
Accession: 1623
RBP type: non-canonical RBP
Summary: This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000432178	CCT8-203	556	-	ENSP00000407748	107 (aa)	-	H7C2U0
ENST00000470450	CCT8-204	1872	-	-	- (aa)	-	-
ENST00000494296	CCT8-209	514	-	-	- (aa)	-	-
ENST00000286788	CCT8-201	2005	-	ENSP00000286788	548 (aa)	-	P50990
ENST00000484403	CCT8-208	808	-	-	- (aa)	-	-
ENST00000475205	CCT8-205	431	-	-	- (aa)	-	-
ENST00000540844	CCT8-211	1927	-	ENSP00000442730	475 (aa)	-	P50990
ENST00000480359	CCT8-206	452	-	-	- (aa)	-	-
ENST00000626972	CCT8-212	1862	-	ENSP00000486921	529 (aa)	-	P50990
ENST00000431234	CCT8-202	968	-	ENSP00000416832	323 (aa)	-	H7C4C8
ENST00000481059	CCT8-207	879	-	-	- (aa)	-	-
ENST00000496121	CCT8-210	1326	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000156261's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000156261's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000156261	CCT8	100	45.694	YJL008C		100	45.694	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002199	zona pellucida receptor complex	-	IEA	Component
GO:0005515	protein binding	14532270.16085932.25467444.30021884.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005576	extracellular region	-	TAS	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	25468996.	IDA	Component
GO:0005813	centrosome	20080638.	IDA	Component
GO:0005829	cytosol	16780588.	HDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005832	chaperonin-containing T-complex	21873635.	IBA	Component
GO:0005832	chaperonin-containing T-complex	23011926.	IDA	Component
GO:0005832	chaperonin-containing T-complex	25467444.	TAS	Component
GO:0005874	microtubule	21525035.	IDA	Component
GO:0005929	cilium	-	IEA	Component
GO:0006457	protein folding	-	TAS	Process
GO:0007339	binding of sperm to zona pellucida	-	IEA	Process
GO:0032212	positive regulation of telomere maintenance via telomerase	25467444.	IMP	Process
GO:0034774	secretory granule lumen	-	TAS	Component
GO:0035578	azurophil granule lumen	-	TAS	Component
GO:0042623	ATPase activity, coupled	7890169.	TAS	Function
GO:0043312	neutrophil degranulation	-	TAS	Process
GO:0044297	cell body	-	IEA	Component
GO:0045111	intermediate filament cytoskeleton	-	IDA	Component
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0046931	pore complex assembly	-	IEA	Process
GO:0050821	protein stabilization	25467444.	IMP	Process
GO:0051082	unfolded protein binding	-	IEA	Function
GO:0070062	extracellular exosome	19056867.20458337.	HDA	Component
GO:1901998	toxin transport	-	IEA	Process
GO:1904813	ficolin-1-rich granule lumen	-	TAS	Component
GO:1904851	positive regulation of establishment of protein localization to telomere	25467444.	IMP	Process
GO:1904871	positive regulation of protein localization to Cajal body	25467444.	HMP	Process
GO:1904874	positive regulation of telomerase RNA localization to Cajal body	25467444.	HMP	Process