EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000156469 (Gene tree)
Gene ID: 51001
Gene Symbol: MTERF3
Alias: CGI-12|FLJ10939|MTERFD1
Full Name: mitochondrial transcription termination factor 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 22,216 bases
Position: chr8:96,239,398-96,261,613
Accession: 24258
RBP type: canonical RBP
Summary: (Mitochondrial Transcription Termination Factor 3) is a Protein Coding gene. Among its related pathways are Pink/Parkin Mediated Mitophagy and Mitochondrial Gene Expression. Gene Ontology (GO) annotations related to this gene include transcription regulatory region DNA binding and double-stranded DNA binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000430138	mTERF	PF02536.14	1.2e-28	1	1
ENSP00000287025	mTERF	PF02536.14	3.2e-28	1	1
ENSP00000429400	mTERF	PF02536.14	5.5e-26	1	1
ENSP00000429267	mTERF	PF02536.14	1.6e-11	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000523821	MTERF3-204	1529	-	ENSP00000429400	361 (aa)	-	E5RIK9
ENST00000524341	MTERF3-205	776	XM_006716570	ENSP00000429267	173 (aa)	-	E5RIY4
ENST00000287025	MTERF3-201	1409	-	ENSP00000287025	417 (aa)	-	Q96E29
ENST00000522822	MTERF3-203	1148	XM_011517054	ENSP00000430138	296 (aa)	XP_011515356	Q96E29
ENST00000517720	MTERF3-202	412	-	ENSP00000429526	67 (aa)	-	E5RI75

Gene Model

Click here to download ENSG00000156469's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000156469	Platelet Function Tests	2.1996700E-005	-
ENSG00000156469	Child Development Disorders, Pervasive	5.0943600E-005	-
ENSG00000156469	Vital Capacity	2E-6	24023788

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000156469	rs7814319	8	96251190	?	Lung function (FVC)	24023788			EFO_0004312

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000156469's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000156469	MTERF3	100	60.135	ENSAPOG00000019410	mterf3	76	57.402	Acanthochromis_polyacanthus
ENSG00000156469	MTERF3	100	91.216	ENSAMEG00000007290	MTERF3	100	88.010	Ailuropoda_melanoleuca
ENSG00000156469	MTERF3	99	63.372	ENSACIG00000010722	mterf3	92	63.372	Amphilophus_citrinellus
ENSG00000156469	MTERF3	100	59.797	ENSAOCG00000007019	mterf3	73	57.812	Amphiprion_ocellaris
ENSG00000156469	MTERF3	100	59.459	ENSAPEG00000012039	mterf3	73	57.812	Amphiprion_percula
ENSG00000156469	MTERF3	100	60.135	ENSATEG00000014098	mterf3	88	60.201	Anabas_testudineus
ENSG00000156469	MTERF3	100	70.946	ENSAPLG00000012750	MTERF3	100	59.233	Anas_platyrhynchos
ENSG00000156469	MTERF3	100	69.257	ENSACAG00000004143	MTERF3	59	69.000	Anolis_carolinensis
ENSG00000156469	MTERF3	100	97.688	ENSANAG00000031075	MTERF3	100	97.688	Aotus_nancymaae
ENSG00000156469	MTERF3	100	61.824	ENSACLG00000016514	mterf3	70	61.745	Astatotilapia_calliptera
ENSG00000156469	MTERF3	99	64.164	ENSAMXG00000020695	mterf3	70	63.455	Astyanax_mexicanus
ENSG00000156469	MTERF3	100	86.824	ENSBTAG00000001522	MTERF3	100	81.295	Bos_taurus
ENSG00000156469	MTERF3	85	32.812	WBGene00008236	C50F4.12	58	32.812	Caenorhabditis_elegans
ENSG00000156469	MTERF3	100	97.110	ENSCJAG00000020561	MTERF3	100	97.110	Callithrix_jacchus
ENSG00000156469	MTERF3	100	91.554	ENSCAFG00000009460	MTERF3	100	85.612	Canis_familiaris
ENSG00000156469	MTERF3	100	91.554	ENSCAFG00020009670	MTERF3	100	85.851	Canis_lupus_dingo
ENSG00000156469	MTERF3	100	90.751	ENSCHIG00000009830	MTERF3	100	90.751	Capra_hircus
ENSG00000156469	MTERF3	99	82.653	ENSTSYG00000036226	-	100	75.540	Carlito_syrichta
ENSG00000156469	MTERF3	100	95.954	ENSTSYG00000007338	-	100	95.954	Carlito_syrichta
ENSG00000156469	MTERF3	100	91.892	ENSCAPG00000007884	MTERF3	100	84.135	Cavia_aperea
ENSG00000156469	MTERF3	100	91.892	ENSCPOG00000003487	MTERF3	100	87.530	Cavia_porcellus
ENSG00000156469	MTERF3	100	96.532	ENSCCAG00000025636	MTERF3	100	96.532	Cebus_capucinus
ENSG00000156469	MTERF3	100	97.635	ENSCATG00000012833	MTERF3	100	97.110	Cercocebus_atys
ENSG00000156469	MTERF3	100	89.527	ENSCLAG00000004692	MTERF3	100	85.132	Chinchilla_lanigera
ENSG00000156469	MTERF3	100	97.635	ENSCSAG00000012442	MTERF3	100	96.368	Chlorocebus_sabaeus
ENSG00000156469	MTERF3	100	90.203	ENSCHOG00000007893	MTERF3	100	84.652	Choloepus_hoffmanni
ENSG00000156469	MTERF3	100	75.338	ENSCPBG00000006293	MTERF3	100	64.200	Chrysemys_picta_bellii
ENSG00000156469	MTERF3	94	31.834	ENSCING00000011397	-	74	31.834	Ciona_intestinalis
ENSG00000156469	MTERF3	82	31.765	ENSCSAVG00000011299	-	74	31.765	Ciona_savignyi
ENSG00000156469	MTERF3	100	98.266	ENSCANG00000032998	MTERF3	100	98.266	Colobus_angolensis_palliatus
ENSG00000156469	MTERF3	100	85.811	ENSCGRG00001020186	Mterf3	100	79.426	Cricetulus_griseus_chok1gshd
ENSG00000156469	MTERF3	100	85.811	ENSCGRG00000002168	Mterf3	100	79.426	Cricetulus_griseus_crigri
ENSG00000156469	MTERF3	100	59.797	ENSCSEG00000017906	mterf3	65	59.732	Cynoglossus_semilaevis
ENSG00000156469	MTERF3	100	60.473	ENSCVAG00000020609	mterf3	71	60.473	Cyprinodon_variegatus
ENSG00000156469	MTERF3	100	61.149	ENSDARG00000003207	mterf3	98	58.108	Danio_rerio
ENSG00000156469	MTERF3	100	91.216	ENSDNOG00000041739	MTERF3	100	85.612	Dasypus_novemcinctus
ENSG00000156469	MTERF3	100	89.527	ENSDORG00000010477	Mterf3	100	82.254	Dipodomys_ordii
ENSG00000156469	MTERF3	93	40.511	FBgn0037008	mTerf3	77	40.511	Drosophila_melanogaster
ENSG00000156469	MTERF3	100	84.797	ENSETEG00000011372	MTERF3	100	76.794	Echinops_telfairi
ENSG00000156469	MTERF3	99	46.801	ENSEBUG00000016986	mterf3	77	46.801	Eptatretus_burgeri
ENSG00000156469	MTERF3	100	90.541	ENSEASG00005003303	MTERF3	100	85.132	Equus_asinus_asinus
ENSG00000156469	MTERF3	100	90.541	ENSECAG00000012943	MTERF3	100	84.892	Equus_caballus
ENSG00000156469	MTERF3	100	82.095	ENSEEUG00000004188	MTERF3	100	79.310	Erinaceus_europaeus
ENSG00000156469	MTERF3	100	61.149	ENSELUG00000019194	mterf3	80	60.797	Esox_lucius
ENSG00000156469	MTERF3	100	90.751	ENSFCAG00000028511	MTERF3	100	90.751	Felis_catus
ENSG00000156469	MTERF3	99	69.625	ENSFALG00000005635	MTERF3	78	64.458	Ficedula_albicollis
ENSG00000156469	MTERF3	100	89.527	ENSFDAG00000020592	MTERF3	99	85.612	Fukomys_damarensis
ENSG00000156469	MTERF3	100	60.473	ENSFHEG00000013330	mterf3	71	60.201	Fundulus_heteroclitus
ENSG00000156469	MTERF3	100	57.770	ENSGMOG00000010492	mterf3	71	57.770	Gadus_morhua
ENSG00000156469	MTERF3	100	68.919	ENSGALG00000040511	MTERF3	82	63.772	Gallus_gallus
ENSG00000156469	MTERF3	100	58.784	ENSGAFG00000010911	mterf3	76	58.863	Gambusia_affinis
ENSG00000156469	MTERF3	99	61.092	ENSGACG00000005407	mterf3	70	60.403	Gasterosteus_aculeatus
ENSG00000156469	MTERF3	100	74.662	ENSGAGG00000001487	MTERF3	100	63.549	Gopherus_agassizii
ENSG00000156469	MTERF3	100	99.723	ENSGGOG00000011535	MTERF3	100	99.723	Gorilla_gorilla
ENSG00000156469	MTERF3	100	61.149	ENSHBUG00000002872	mterf3	70	61.074	Haplochromis_burtoni
ENSG00000156469	MTERF3	100	91.554	ENSHGLG00000013588	MTERFD1	100	88.010	Heterocephalus_glaber_female
ENSG00000156469	MTERF3	100	91.554	ENSHGLG00100018033	MTERFD1	100	88.010	Heterocephalus_glaber_male
ENSG00000156469	MTERF3	100	57.770	ENSHCOG00000019365	mterf3	76	57.475	Hippocampus_comes
ENSG00000156469	MTERF3	99	62.116	ENSIPUG00000014124	mterf3	73	61.873	Ictalurus_punctatus
ENSG00000156469	MTERF3	98	92.096	ENSSTOG00000008021	MTERF3	100	85.851	Ictidomys_tridecemlineatus
ENSG00000156469	MTERF3	99	90.116	ENSJJAG00000011745	-	100	90.116	Jaculus_jaculus
ENSG00000156469	MTERF3	100	60.135	ENSKMAG00000006393	mterf3	70	60.135	Kryptolebias_marmoratus
ENSG00000156469	MTERF3	100	60.135	ENSLBEG00000002946	mterf3	70	60.067	Labrus_bergylta
ENSG00000156469	MTERF3	99	68.259	ENSLACG00000003492	MTERF3	100	57.041	Latimeria_chalumnae
ENSG00000156469	MTERF3	99	67.577	ENSLOCG00000008210	mterf3	97	67.442	Lepisosteus_oculatus
ENSG00000156469	MTERF3	100	90.203	ENSLAFG00000002544	MTERF3	100	84.412	Loxodonta_africana
ENSG00000156469	MTERF3	100	97.973	ENSMFAG00000042157	MTERF3	100	97.688	Macaca_fascicularis
ENSG00000156469	MTERF3	100	97.973	ENSMMUG00000008808	MTERF3	100	97.688	Macaca_mulatta
ENSG00000156469	MTERF3	100	97.973	ENSMNEG00000039418	MTERF3	100	97.688	Macaca_nemestrina
ENSG00000156469	MTERF3	100	97.635	ENSMLEG00000029214	MTERF3	100	97.110	Mandrillus_leucophaeus
ENSG00000156469	MTERF3	100	60.811	ENSMAMG00000013266	mterf3	68	60.738	Mastacembelus_armatus
ENSG00000156469	MTERF3	100	61.824	ENSMZEG00005004309	mterf3	70	61.745	Maylandia_zebra
ENSG00000156469	MTERF3	100	86.149	ENSMAUG00000014336	Mterf3	100	79.376	Mesocricetus_auratus
ENSG00000156469	MTERF3	100	93.064	ENSMICG00000033467	MTERF3	100	93.064	Microcebus_murinus
ENSG00000156469	MTERF3	100	85.473	ENSMOCG00000009078	Mterf3	100	78.417	Microtus_ochrogaster
ENSG00000156469	MTERF3	100	63.006	ENSMMOG00000019038	mterf3	100	63.006	Mola_mola
ENSG00000156469	MTERF3	100	79.392	ENSMODG00000006966	MTERF3	100	70.743	Monodelphis_domestica
ENSG00000156469	MTERF3	100	63.006	ENSMALG00000013895	mterf3	100	63.006	Monopterus_albus
ENSG00000156469	MTERF3	100	84.459	MGP_CAROLIEiJ_G0018654	Mterf3	100	76.499	Mus_caroli
ENSG00000156469	MTERF3	100	84.797	ENSMUSG00000021519	Mterf3	100	76.019	Mus_musculus
ENSG00000156469	MTERF3	100	83.108	MGP_PahariEiJ_G0019719	Mterf3	100	75.540	Mus_pahari
ENSG00000156469	MTERF3	100	85.473	MGP_SPRETEiJ_G0019536	Mterf3	100	76.739	Mus_spretus
ENSG00000156469	MTERF3	100	90.878	ENSMPUG00000008759	MTERF3	100	87.530	Mustela_putorius_furo
ENSG00000156469	MTERF3	100	91.892	ENSMLUG00000007186	MTERF3	100	86.124	Myotis_lucifugus
ENSG00000156469	MTERF3	100	90.878	ENSNGAG00000017410	Mterf3	100	83.493	Nannospalax_galili
ENSG00000156469	MTERF3	100	61.486	ENSNBRG00000012537	mterf3	70	61.409	Neolamprologus_brichardi
ENSG00000156469	MTERF3	100	100.000	ENSNLEG00000003582	MTERF3	100	100.000	Nomascus_leucogenys
ENSG00000156469	MTERF3	98	62.890	ENSMEUG00000000728	-	100	62.890	Notamacropus_eugenii
ENSG00000156469	MTERF3	100	80.743	ENSOPRG00000008899	MTERF3	100	73.621	Ochotona_princeps
ENSG00000156469	MTERF3	100	87.861	ENSODEG00000002232	MTERF3	96	84.259	Octodon_degus
ENSG00000156469	MTERF3	100	61.149	ENSONIG00000002550	mterf3	70	61.074	Oreochromis_niloticus
ENSG00000156469	MTERF3	99	75.510	ENSOANG00000001415	MTERF3	100	67.386	Ornithorhynchus_anatinus
ENSG00000156469	MTERF3	100	92.568	ENSOCUG00000004276	MTERF3	100	84.652	Oryctolagus_cuniculus
ENSG00000156469	MTERF3	100	57.770	ENSORLG00000012689	mterf3	70	57.770	Oryzias_latipes
ENSG00000156469	MTERF3	100	57.770	ENSORLG00020006060	mterf3	70	57.770	Oryzias_latipes_hni
ENSG00000156469	MTERF3	100	58.446	ENSORLG00015013903	mterf3	70	58.446	Oryzias_latipes_hsok
ENSG00000156469	MTERF3	100	58.108	ENSOMEG00000012111	mterf3	90	58.054	Oryzias_melastigma
ENSG00000156469	MTERF3	100	92.230	ENSOGAG00000004303	MTERF3	100	87.050	Otolemur_garnettii
ENSG00000156469	MTERF3	100	74.662	ENSOARG00000020668	-	100	70.024	Ovis_aries
ENSG00000156469	MTERF3	100	87.838	ENSOARG00000005313	-	84	80.815	Ovis_aries
ENSG00000156469	MTERF3	100	100.000	ENSPPAG00000030040	MTERF3	100	100.000	Pan_paniscus
ENSG00000156469	MTERF3	100	90.751	ENSPPRG00000022053	MTERF3	100	90.751	Panthera_pardus
ENSG00000156469	MTERF3	100	90.751	ENSPTIG00000013347	MTERF3	100	90.751	Panthera_tigris_altaica
ENSG00000156469	MTERF3	100	100.000	ENSPTRG00000020441	MTERF3	100	100.000	Pan_troglodytes
ENSG00000156469	MTERF3	100	97.973	ENSPANG00000000418	MTERF3	100	97.688	Papio_anubis
ENSG00000156469	MTERF3	99	65.529	ENSPKIG00000005444	mterf3	69	65.116	Paramormyrops_kingsleyae
ENSG00000156469	MTERF3	99	62.209	ENSPMGG00000022632	mterf3	92	62.209	Periophthalmus_magnuspinnatus
ENSG00000156469	MTERF3	100	85.811	ENSPEMG00000023323	Mterf3	100	79.616	Peromyscus_maniculatus_bairdii
ENSG00000156469	MTERF3	100	79.054	ENSPCIG00000028355	MTERF3	100	71.942	Phascolarctos_cinereus
ENSG00000156469	MTERF3	100	60.135	ENSPFOG00000013383	mterf3	70	60.201	Poecilia_formosa
ENSG00000156469	MTERF3	100	60.473	ENSPLAG00000014923	mterf3	70	60.535	Poecilia_latipinna
ENSG00000156469	MTERF3	100	59.797	ENSPMEG00000021606	mterf3	70	59.866	Poecilia_mexicana
ENSG00000156469	MTERF3	99	61.628	ENSPREG00000007531	mterf3	97	61.628	Poecilia_reticulata
ENSG00000156469	MTERF3	100	100.000	ENSPPYG00000018764	MTERF3	97	98.801	Pongo_abelii
ENSG00000156469	MTERF3	100	90.203	ENSPCAG00000009302	MTERF3	100	83.254	Procavia_capensis
ENSG00000156469	MTERF3	100	85.075	ENSPCOG00000024551	MTERF3	100	66.194	Propithecus_coquereli
ENSG00000156469	MTERF3	100	85.473	ENSPVAG00000012322	MTERF3	100	76.372	Pteropus_vampyrus
ENSG00000156469	MTERF3	100	60.473	ENSPNYG00000011322	mterf3	70	60.403	Pundamilia_nyererei
ENSG00000156469	MTERF3	99	63.823	ENSPNAG00000025430	mterf3	70	63.123	Pygocentrus_nattereri
ENSG00000156469	MTERF3	100	86.486	ENSRNOG00000004492	Mterf3	100	76.499	Rattus_norvegicus
ENSG00000156469	MTERF3	99	97.279	ENSRBIG00000043536	MTERF3	100	95.568	Rhinopithecus_bieti
ENSG00000156469	MTERF3	100	97.297	ENSRROG00000028594	MTERF3	100	96.532	Rhinopithecus_roxellana
ENSG00000156469	MTERF3	100	95.376	ENSSBOG00000027056	MTERF3	100	95.376	Saimiri_boliviensis_boliviensis
ENSG00000156469	MTERF3	100	78.378	ENSSHAG00000005026	MTERF3	100	71.703	Sarcophilus_harrisii
ENSG00000156469	MTERF3	99	65.529	ENSSFOG00015010739	mterf3	70	65.116	Scleropages_formosus
ENSG00000156469	MTERF3	100	60.135	ENSSMAG00000008368	mterf3	70	59.866	Scophthalmus_maximus
ENSG00000156469	MTERF3	100	61.824	ENSSDUG00000010892	mterf3	70	61.745	Seriola_dumerili
ENSG00000156469	MTERF3	100	62.162	ENSSLDG00000012787	mterf3	70	62.081	Seriola_lalandi_dorsalis
ENSG00000156469	MTERF3	100	80.743	ENSSARG00000003032	MTERF3	99	80.731	Sorex_araneus
ENSG00000156469	MTERF3	89	69.847	ENSSPUG00000012167	MTERF3	96	59.530	Sphenodon_punctatus
ENSG00000156469	MTERF3	100	60.811	ENSSPAG00000014873	mterf3	70	60.738	Stegastes_partitus
ENSG00000156469	MTERF3	100	90.878	ENSSSCG00000006090	MTERF3	100	86.091	Sus_scrofa
ENSG00000156469	MTERF3	100	68.919	ENSTGUG00000011961	MTERF3	98	68.771	Taeniopygia_guttata
ENSG00000156469	MTERF3	100	60.135	ENSTRUG00000010597	mterf3	72	59.801	Takifugu_rubripes
ENSG00000156469	MTERF3	100	59.459	ENSTNIG00000009184	mterf3	99	59.136	Tetraodon_nigroviridis
ENSG00000156469	MTERF3	100	92.905	ENSTBEG00000002615	MTERF3	100	87.500	Tupaia_belangeri
ENSG00000156469	MTERF3	100	90.203	ENSTTRG00000007349	MTERF3	100	84.173	Tursiops_truncatus
ENSG00000156469	MTERF3	100	91.554	ENSUAMG00000000137	MTERF3	100	87.770	Ursus_americanus
ENSG00000156469	MTERF3	100	91.554	ENSUMAG00000016674	MTERF3	100	87.770	Ursus_maritimus
ENSG00000156469	MTERF3	100	92.230	ENSVPAG00000004132	MTERF3	100	86.331	Vicugna_pacos
ENSG00000156469	MTERF3	100	91.892	ENSVVUG00000003230	MTERF3	92	85.612	Vulpes_vulpes
ENSG00000156469	MTERF3	100	58.108	ENSXMAG00000003462	mterf3	70	58.194	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003690	double-stranded DNA binding	-	IEA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	17662942.	IDA	Component
GO:0005741	mitochondrial outer membrane	-	TAS	Component
GO:0006390	mitochondrial transcription	21873635.	IBA	Process
GO:0016236	macroautophagy	-	TAS	Process
GO:0032543	mitochondrial translation	21873635.	IBA	Process
GO:0044212	transcription regulatory region DNA binding	17662942.	IDA	Function
GO:0045892	negative regulation of transcription, DNA-templated	17662942.	IMP	Process
GO:0061668	mitochondrial ribosome assembly	21873635.	IBA	Process

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr8	96244068	Nonsense_Mutation	novel	E304*	0.23
BLCA	chr8	96244055	Missense_Mutation	novel	K308T	0.53
BLCA	chr8	96239559	Missense_Mutation	novel	E396K	0.52
BLCA	chr8	96257088	Missense_Mutation	NA	P121A	0.18
BRCA	chr8	96246322	Silent	NA	E270E	0.23
BRCA	chr8	96250948	Missense_Mutation	NA	N212T	0.5
BRCA	chr8	96244068	Frame_Shift_Ins	novel	*E304Pfs8**	0.04
BRCA	chr8	96257233	Intron	novel		0.12
CESC	chr8	96246324	Missense_Mutation	novel	E270K	0.1
CESC	chr8	96246362	Missense_Mutation	novel	R257T	0.26
COAD	chr8	96245901	Silent	NA	L286L	0.47
COAD	chr8	96239570	Missense_Mutation	rs370527769	S392Y	0.31
COAD	chr8	96258377	Missense_Mutation	NA	D105G	0.28
COAD	chr8	96239640	Missense_Mutation	novel	L369I	0.15
COAD	chr8	96244041	Nonsense_Mutation	NA	Q313*	0.44
COAD	chr8	96257010	Nonsense_Mutation	rs145305126	R147*	0.29
COAD	chr8	96239671	Silent	NA	R358R	0.57
COAD	chr8	96245878	Silent	rs369638814	P293P	0.33
COAD	chr8	96245864	Missense_Mutation	NA	M298K	0.71
COAD	chr8	96244073	Missense_Mutation	rs374910514	R302H	0.2
COAD	chr8	96244042	Silent	NA	I312I	0.07
COAD	chr8	96239470	3'UTR	novel		0.21
ESCA	chr8	96250947	Frame_Shift_Ins	rs759886730	*N212Kfs7**	0.33
ESCA	chr8	96258365	Missense_Mutation	novel	F109C	0.34
GBM	chr8	96256996	Missense_Mutation	novel	D151E	0.08
GBM	chr8	96258499	Silent	novel	S64S	0.06
GBM	chr8	96257040	Missense_Mutation	novel	P137S	0.29
HNSC	chr8	96256993	Silent	novel	H152H	0.43
HNSC	chr8	96239662	Missense_Mutation	novel	K361N	0.14
HNSC	chr8	96258640	Missense_Mutation	novel	L17F	0.15	mTERF
HNSC	chr8	96250914	Silent	novel	L223L	0.28
KIRC	chr8	96246419	Missense_Mutation	NA	A238V	0.08
LAML	chr8	96243941	Missense_Mutation	novel	H346R	0.17
LGG	chr8	96243969	Missense_Mutation	NA	V337M	0.23
LUAD	chr8	96243964	Silent	NA	H338H	0.69
LUAD	chr8	96257082	Nonsense_Mutation	novel	Q123*	0.24
LUAD	chr8	96258561	Nonsense_Mutation	NA	Q44*	0.08	mTERF
LUAD	chr8	96243956	Missense_Mutation	novel	M341K	0.2
LUAD	chr8	96257037	Missense_Mutation	novel	P138S	0.22
LUAD	chr8	96244028	Missense_Mutation	NA	T317N	0.21
LUAD	chr8	96258575	Missense_Mutation	novel	H39R	0.25	mTERF
LUAD	chr8	96258504	Missense_Mutation	NA	T63S	0.18	mTERF
LUAD	chr8	96258522	Nonsense_Mutation	novel	G57*	0.11	mTERF
LUSC	chr8	96239522	Missense_Mutation	novel	Q408L	0.04
LUSC	chr8	96239686	Splice_Site	novel	X354_splice	0.16
LUSC	chr8	96251062	Missense_Mutation	novel	E174V	0.12
LUSC	chr8	96251091	Silent	novel	V164V	0.26
LUSC	chr8	96250947	Frame_Shift_Ins	rs759886730	*N212Kfs7**	0.11
LUSC	chr8	96258566	Missense_Mutation	novel	S42F	0.31	mTERF
LUSC	chr8	96251057	Missense_Mutation	novel	A176P	0.51
LUSC	chr8	96257067	Nonsense_Mutation	NA	E128*	0.42
LUSC	chr8	96251096	Splice_Site	NA	X163_splice	0.21
LUSC	chr8	96244001	Missense_Mutation	NA	N326I	0.2
OV	chr8	96244001	Missense_Mutation	NA	N326I	0.14
OV	chr8	96239527	Silent	NA	S406S	0.43
PAAD	chr8	96250907	Missense_Mutation	novel	R226W	0.18
PAAD	chr8	96257177	Intron	novel		0.22
PRAD	chr8	96257113	Splice_Region	NA	E112E	0.05
READ	chr8	96257215	Intron	novel		0.71
READ	chr8	96239482	3'UTR	novel		0.09
READ	chr8	96257133	Intron	novel		0.18
READ	chr8	96239506	Missense_Mutation	NA	F413L	0.39
SKCM	chr8	96245922	Silent	NA	L279L	0.43
SKCM	chr8	96245924	Missense_Mutation	NA	D278V	0.43
SKCM	chr8	96246367	Silent	NA	V255V	0.26
SKCM	chr8	96245913	Missense_Mutation	rs750241466	R282C	0.2
SKCM	chr8	96257220	Intron	novel		0.2
SKCM	chr8	96239485	3'UTR	novel		0.16
SKCM	chr8	96246357	Missense_Mutation	NA	D259N	0.66
SKCM	chr8	96258498	Missense_Mutation	NA	S65A	0.27	mTERF
SKCM	chr8	96258572	Missense_Mutation	rs148966759	G40D	0.15	mTERF
SKCM	chr8	96258405	Nonsense_Mutation	NA	Q96*	0.3	mTERF
SKCM	chr8	96250946	Missense_Mutation	rs148129681	H213Y	0.17
SKCM	chr8	96245908	Silent	NA	L283L	0.36
SKCM	chr8	96243925	Silent	novel	F351F	0.56
STAD	chr8	96239552	Missense_Mutation	novel	F398S	0.24
STAD	chr8	96257170	Intron	novel		0.2
STAD	chr8	96257028	Missense_Mutation	NA	P141S	0.09
STAD	chr8	96239499	Frame_Shift_Del	novel	*T416Rfs15**	0.13
STAD	chr8	96257068	Missense_Mutation	NA	E127D	0.12
STAD	chr8	96258571	Silent	NA	G40G	0.2
STAD	chr8	96246383	Frame_Shift_Del	novel	*L250Cfs2**	0.14
STAD	chr8	96239687	Splice_Site	novel	X354_splice	0.13
TGCT	chr8	96251066	Missense_Mutation	novel	P173S	0.26
THCA	chr8	96239497	Silent	rs377656018	T416T	0.38
THCA	chr8	96257227	Intron	novel		0.19
THCA	chr8	96257229	Intron	novel		0.13
THYM	chr8	96245883	Nonsense_Mutation	novel	E292*	0.04
THYM	chr8	96245884	Silent	novel	L291L	0.04
UCEC	chr8	96244047	Missense_Mutation	rs778548567	E311K	0.32
UCEC	chr8	96239611	Silent	NA	D378D	0.22
UCEC	chr8	96258515	Missense_Mutation	novel	K59T	0.39	mTERF
UCEC	chr8	96246430	Frame_Shift_Ins	novel	*N234Kfs4**	0.46
UCEC	chr8	96251079	Silent	novel	K168K	0.43
UCEC	chr8	96246336	Frame_Shift_Ins	rs769712312	*Q266Sfs5**	0.17
UCEC	chr8	96239506	Missense_Mutation	NA	F413L	0.23
UCEC	chr8	96257168	Intron	novel		0.26
UCEC	chr8	96258670	Missense_Mutation	novel	Q7H	0.09	mTERF
UCEC	chr8	96257223	Intron	novel		0.63
UCEC	chr8	96246310	Missense_Mutation	novel	K274N	0.15
UCEC	chr8	96251093	Missense_Mutation	rs549182133	V164M	0.32
UCEC	chr8	96239443	3'UTR	novel		0.28
UCEC	chr8	96257083	Missense_Mutation	NA	M122I	0.39
UCEC	chr8	96246392	Missense_Mutation	novel	A247V	0.4
UCEC	chr8	96257062	Silent	novel	E129E	0.09
UCEC	chr8	96239486	3'UTR	novel		0.41
UCEC	chr8	96244002	Missense_Mutation	novel	N326H	0.15
UCEC	chr8	96258552	Missense_Mutation	novel	I47L	0.34	mTERF
UCEC	chr8	96258547	Silent	NA	S48S	0.26
UCEC	chr8	96258473	Missense_Mutation	novel	T73I	0.07	mTERF
UCEC	chr8	96258695	5'UTR	novel		0.1
UCEC	chr8	96244047	Missense_Mutation	rs778548567	E311K	0.42
UCEC	chr8	96250994	Missense_Mutation	NA	D197Y	0.3
UCEC	chr8	96239453	3'UTR	novel		0.37
UCEC	chr8	96257233	Intron	novel		0.07
UCEC	chr8	96246374	Missense_Mutation	novel	F253S	0.26
UCEC	chr8	96251093	Missense_Mutation	rs549182133	V164M	0.31

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRC	AMP	0.1023	0.15559
PRAD	AMP	0.2642	3.7005e-05
SARC	AMP	0.2957	0.18425
TGCT	AMP	0.6667	0.13696
THCA	DEL	0.008	0.038162

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00011	Kaplan-Meier Survival Analysis
STAD	0.016	Kaplan-Meier Survival Analysis
MESO	0.039	Kaplan-Meier Survival Analysis
HNSC	0.042	Kaplan-Meier Survival Analysis
BRCA	0.032	Kaplan-Meier Survival Analysis
KIRP	0.0081	Kaplan-Meier Survival Analysis
BLCA	0.00064	Kaplan-Meier Survival Analysis
KICH	0.013	Kaplan-Meier Survival Analysis
UCEC	0.019	Kaplan-Meier Survival Analysis
LIHC	0.00017	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.042	Kaplan-Meier Survival Analysis
UVM	0.00054	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742