EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000156697 (Gene tree)
Gene ID: 10813
Gene Symbol: UTP14A
Alias: NY-CO-16|Utp14|SDCCAG16
Full Name: UTP14A small subunit processome component
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 23,642 bases
Position: chrX:129,906,121-129,929,762
Accession: 10665
RBP type: canonical RBP
Summary: This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000377944	Utp14	PF04615.13	2.2e-179	1	1
ENSP00000388669	Utp14	PF04615.13	6.1e-152	1	2
ENSP00000388669	Utp14	PF04615.13	6.1e-152	2	2
ENSP00000413187	Utp14	PF04615.13	5.9e-62	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000425117	UTP14A-202	2403	XM_017029237	ENSP00000388669	719 (aa)	XP_016884726	Q9BVJ6
ENST00000498179	UTP14A-204	1910	-	-	- (aa)	-	-
ENST00000427972	UTP14A-203	979	-	ENSP00000413187	320 (aa)	-	X6RJY0
ENST00000394422	UTP14A-201	2488	-	ENSP00000377944	771 (aa)	-	Q9BVJ6

Gene Model

Click here to download ENSG00000156697's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000156697	Child Development Disorders, Pervasive	5.0000000E-005	-
ENSG00000156697	Child Development Disorders, Pervasive	7.2000000E-005	-
ENSG00000156697	Child Development Disorders, Pervasive	6.2000000E-005	-
ENSG00000156697	Periodontitis	5E-6	24024966

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000156697's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000156697	UTP14A	99	89.831	ENSG00000253797	UTP14C	99	89.048

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000156697	UTP14A	93	48.448	ENSAPOG00000011615	si:dkey-251i10.3	96	48.853	Acanthochromis_polyacanthus
ENSG00000156697	UTP14A	100	84.994	ENSAMEG00000015001	-	98	84.994	Ailuropoda_melanoleuca
ENSG00000156697	UTP14A	92	46.395	ENSACIG00000004000	si:dkey-251i10.3	93	47.043	Amphilophus_citrinellus
ENSG00000156697	UTP14A	91	48.536	ENSAOCG00000023132	si:dkey-251i10.3	90	48.704	Amphiprion_ocellaris
ENSG00000156697	UTP14A	91	48.257	ENSAPEG00000023935	si:dkey-251i10.3	92	48.493	Amphiprion_percula
ENSG00000156697	UTP14A	91	57.338	ENSATEG00000005429	si:dkey-251i10.3	96	49.729	Anabas_testudineus
ENSG00000156697	UTP14A	88	57.951	ENSACAG00000009064	-	55	53.132	Anolis_carolinensis
ENSG00000156697	UTP14A	83	90.286	ENSANAG00000038103	UTP14C	95	90.286	Aotus_nancymaae
ENSG00000156697	UTP14A	100	85.123	ENSANAG00000027545	-	100	84.217	Aotus_nancymaae
ENSG00000156697	UTP14A	96	91.586	ENSANAG00000027648	-	98	91.134	Aotus_nancymaae
ENSG00000156697	UTP14A	94	47.319	ENSACLG00000006291	si:dkey-251i10.3	99	46.862	Astatotilapia_calliptera
ENSG00000156697	UTP14A	92	48.910	ENSAMXG00000006658	si:dkey-251i10.3	92	48.229	Astyanax_mexicanus
ENSG00000156697	UTP14A	100	79.199	ENSBTAG00000013671	UTP14A	100	79.328	Bos_taurus
ENSG00000156697	UTP14A	65	35.326	WBGene00017855	F27C1.6	65	39.437	Caenorhabditis_elegans
ENSG00000156697	UTP14A	97	86.684	ENSCJAG00000008414	UTP14C	96	86.667	Callithrix_jacchus
ENSG00000156697	UTP14A	100	93.046	ENSCJAG00000002637	UTP14A	100	92.907	Callithrix_jacchus
ENSG00000156697	UTP14A	100	83.312	ENSCAFG00000018717	-	100	83.312	Canis_familiaris
ENSG00000156697	UTP14A	100	83.441	ENSCAFG00020001499	-	100	83.441	Canis_lupus_dingo
ENSG00000156697	UTP14A	100	64.987	ENSCHIG00000022738	-	100	64.341	Capra_hircus
ENSG00000156697	UTP14A	100	79.457	ENSCHIG00000010313	-	100	79.716	Capra_hircus
ENSG00000156697	UTP14A	100	77.778	ENSCHIG00000005255	-	100	78.036	Capra_hircus
ENSG00000156697	UTP14A	100	86.434	ENSTSYG00000009415	-	100	86.434	Carlito_syrichta
ENSG00000156697	UTP14A	100	74.223	ENSCPOG00000035705	-	99	74.093	Cavia_porcellus
ENSG00000156697	UTP14A	97	80.000	ENSCPOG00000014231	-	98	80.758	Cavia_porcellus
ENSG00000156697	UTP14A	100	93.750	ENSCCAG00000035074	UTP14A	99	93.994	Cebus_capucinus
ENSG00000156697	UTP14A	100	97.150	ENSCATG00000036177	UTP14A	100	97.150	Cercocebus_atys
ENSG00000156697	UTP14A	100	83.571	ENSCLAG00000001444	-	99	83.312	Chinchilla_lanigera
ENSG00000156697	UTP14A	100	75.259	ENSCLAG00000002314	-	99	74.741	Chinchilla_lanigera
ENSG00000156697	UTP14A	99	89.235	ENSCSAG00000018620	UTP14C	99	89.235	Chlorocebus_sabaeus
ENSG00000156697	UTP14A	100	97.536	ENSCSAG00000008164	UTP14A	100	97.536	Chlorocebus_sabaeus
ENSG00000156697	UTP14A	90	82.639	ENSCHOG00000009675	-	100	85.178	Choloepus_hoffmanni
ENSG00000156697	UTP14A	75	88.285	ENSCHOG00000001479	-	100	85.995	Choloepus_hoffmanni
ENSG00000156697	UTP14A	95	78.689	ENSCHOG00000009735	-	100	77.710	Choloepus_hoffmanni
ENSG00000156697	UTP14A	93	56.606	ENSCPBG00000012018	-	95	55.710	Chrysemys_picta_bellii
ENSG00000156697	UTP14A	100	97.406	ENSCANG00000042754	UTP14A	100	97.406	Colobus_angolensis_palliatus
ENSG00000156697	UTP14A	97	88.673	ENSCANG00000041630	UTP14C	99	89.024	Colobus_angolensis_palliatus
ENSG00000156697	UTP14A	100	77.878	ENSCGRG00001013594	Utp14a	100	77.749	Cricetulus_griseus_chok1gshd
ENSG00000156697	UTP14A	99	70.588	ENSCGRG00000018531	Utp14b	99	70.232	Cricetulus_griseus_crigri
ENSG00000156697	UTP14A	100	77.620	ENSCGRG00000014784	Utp14a	100	77.490	Cricetulus_griseus_crigri
ENSG00000156697	UTP14A	95	45.136	ENSCSEG00000009241	si:dkey-251i10.3	61	49.892	Cynoglossus_semilaevis
ENSG00000156697	UTP14A	94	48.309	ENSCVAG00000010387	si:dkey-251i10.3	58	56.325	Cyprinodon_variegatus
ENSG00000156697	UTP14A	67	65.116	ENSDARG00000042520	UTP14C	52	55.634	Danio_rerio
ENSG00000156697	UTP14A	100	85.032	ENSDNOG00000002180	-	97	84.645	Dasypus_novemcinctus
ENSG00000156697	UTP14A	97	72.836	ENSDORG00000002224	-	98	72.836	Dipodomys_ordii
ENSG00000156697	UTP14A	99	80.362	ENSDORG00000009761	-	99	80.362	Dipodomys_ordii
ENSG00000156697	UTP14A	81	84.874	ENSETEG00000011606	-	85	84.874	Echinops_telfairi
ENSG00000156697	UTP14A	100	84.994	ENSEASG00005007686	-	100	84.994	Equus_asinus_asinus
ENSG00000156697	UTP14A	100	85.123	ENSECAG00000022718	-	100	85.123	Equus_caballus
ENSG00000156697	UTP14A	91	80.447	ENSEEUG00000015189	-	89	80.447	Erinaceus_europaeus
ENSG00000156697	UTP14A	95	47.607	ENSELUG00000021853	si:dkey-251i10.3	96	46.701	Esox_lucius
ENSG00000156697	UTP14A	100	85.278	ENSFCAG00000001798	-	100	85.278	Felis_catus
ENSG00000156697	UTP14A	91	52.276	ENSFALG00000011665	-	59	56.532	Ficedula_albicollis
ENSG00000156697	UTP14A	98	83.004	ENSFDAG00000016503	-	98	83.004	Fukomys_damarensis
ENSG00000156697	UTP14A	92	56.311	ENSFHEG00000000891	si:dkey-251i10.3	89	48.224	Fundulus_heteroclitus
ENSG00000156697	UTP14A	92	48.571	ENSGMOG00000018246	si:dkey-251i10.3	97	47.914	Gadus_morhua
ENSG00000156697	UTP14A	90	53.942	ENSGALG00000024039	-	52	60.391	Gallus_gallus
ENSG00000156697	UTP14A	83	58.672	ENSGAFG00000014619	si:dkey-251i10.3	57	51.936	Gambusia_affinis
ENSG00000156697	UTP14A	94	47.215	ENSGACG00000001488	si:dkey-251i10.3	98	47.581	Gasterosteus_aculeatus
ENSG00000156697	UTP14A	96	54.692	ENSGAGG00000009461	-	98	52.848	Gopherus_agassizii
ENSG00000156697	UTP14A	100	99.481	ENSGGOG00000014930	UTP14A	100	99.481	Gorilla_gorilla
ENSG00000156697	UTP14A	93	47.962	ENSHBUG00000000649	si:dkey-251i10.3	97	46.325	Haplochromis_burtoni
ENSG00000156697	UTP14A	98	83.884	ENSHGLG00000002939	-	99	83.355	Heterocephalus_glaber_female
ENSG00000156697	UTP14A	99	76.501	ENSHGLG00000019736	-	98	76.371	Heterocephalus_glaber_female
ENSG00000156697	UTP14A	99	76.501	ENSHGLG00100019871	-	98	76.371	Heterocephalus_glaber_male
ENSG00000156697	UTP14A	98	83.884	ENSHGLG00100000360	-	99	83.355	Heterocephalus_glaber_male
ENSG00000156697	UTP14A	55	66.460	ENSHCOG00000020563	UTP14C	81	64.596	Hippocampus_comes
ENSG00000156697	UTP14A	86	58.451	ENSIPUG00000020575	UTP14A	58	52.321	Ictalurus_punctatus
ENSG00000156697	UTP14A	100	83.592	ENSSTOG00000008246	-	100	83.333	Ictidomys_tridecemlineatus
ENSG00000156697	UTP14A	96	73.423	ENSJJAG00000014697	Utp14b	96	73.423	Jaculus_jaculus
ENSG00000156697	UTP14A	100	79.355	ENSJJAG00000023063	Utp14a	100	79.355	Jaculus_jaculus
ENSG00000156697	UTP14A	90	48.159	ENSKMAG00000003300	si:dkey-251i10.3	84	53.514	Kryptolebias_marmoratus
ENSG00000156697	UTP14A	92	48.957	ENSLBEG00000022133	si:dkey-251i10.3	97	48.374	Labrus_bergylta
ENSG00000156697	UTP14A	97	56.574	ENSLACG00000014376	si:dkey-251i10.3	99	54.231	Latimeria_chalumnae
ENSG00000156697	UTP14A	93	52.151	ENSLOCG00000015298	si:dkey-251i10.3	87	52.853	Lepisosteus_oculatus
ENSG00000156697	UTP14A	99	77.850	ENSLAFG00000027486	-	99	77.461	Loxodonta_africana
ENSG00000156697	UTP14A	98	84.980	ENSLAFG00000016653	-	98	84.453	Loxodonta_africana
ENSG00000156697	UTP14A	100	97.280	ENSMFAG00000032552	UTP14A	100	97.280	Macaca_fascicularis
ENSG00000156697	UTP14A	100	97.222	ENSMMUG00000020700	UTP14A	100	97.222	Macaca_mulatta
ENSG00000156697	UTP14A	88	90.071	ENSMNEG00000035132	UTP14C	98	90.603	Macaca_nemestrina
ENSG00000156697	UTP14A	97	96.774	ENSMNEG00000038730	UTP14A	100	97.425	Macaca_nemestrina
ENSG00000156697	UTP14A	100	97.021	ENSMLEG00000029914	UTP14A	100	97.021	Mandrillus_leucophaeus
ENSG00000156697	UTP14A	94	48.016	ENSMAMG00000007406	si:dkey-251i10.3	96	47.425	Mastacembelus_armatus
ENSG00000156697	UTP14A	93	47.418	ENSMZEG00005013633	si:dkey-251i10.3	95	46.527	Maylandia_zebra
ENSG00000156697	UTP14A	91	53.250	ENSMGAG00000001916	-	95	52.235	Meleagris_gallopavo
ENSG00000156697	UTP14A	84	80.741	ENSMAUG00000017487	Utp14a	99	85.366	Mesocricetus_auratus
ENSG00000156697	UTP14A	100	87.204	ENSMICG00000005161	-	100	87.761	Microcebus_murinus
ENSG00000156697	UTP14A	100	77.620	ENSMOCG00000002489	Utp14a	100	77.620	Microtus_ochrogaster
ENSG00000156697	UTP14A	100	69.430	ENSMOCG00000000901	Utp14b	97	68.394	Microtus_ochrogaster
ENSG00000156697	UTP14A	95	48.663	ENSMMOG00000019165	si:dkey-251i10.3	59	54.245	Mola_mola
ENSG00000156697	UTP14A	93	62.171	ENSMODG00000013238	-	91	58.289	Monodelphis_domestica
ENSG00000156697	UTP14A	94	48.505	ENSMALG00000009731	si:dkey-251i10.3	97	49.038	Monopterus_albus
ENSG00000156697	UTP14A	97	67.203	MGP_CAROLIEiJ_G0014313	-	100	66.471	Mus_caroli
ENSG00000156697	UTP14A	100	76.947	MGP_CAROLIEiJ_G0033040	Utp14a	99	76.684	Mus_caroli
ENSG00000156697	UTP14A	99	68.442	ENSMUSG00000079470	Utp14b	97	67.532	Mus_musculus
ENSG00000156697	UTP14A	97	79.808	ENSMUSG00000063785	Utp14a	99	76.943	Mus_musculus
ENSG00000156697	UTP14A	100	68.605	MGP_PahariEiJ_G0027551	Utp14b	100	67.442	Mus_pahari
ENSG00000156697	UTP14A	100	77.882	MGP_PahariEiJ_G0031585	Utp14a	99	77.332	Mus_pahari
ENSG00000156697	UTP14A	97	79.808	MGP_SPRETEiJ_G0034198	Utp14a	99	77.202	Mus_spretus
ENSG00000156697	UTP14A	99	68.312	MGP_SPRETEiJ_G0015119	Utp14b	97	67.792	Mus_spretus
ENSG00000156697	UTP14A	99	83.594	ENSMPUG00000017436	-	99	84.115	Mustela_putorius_furo
ENSG00000156697	UTP14A	99	82.592	ENSMLUG00000005692	-	99	81.806	Myotis_lucifugus
ENSG00000156697	UTP14A	99	84.915	ENSMLUG00000001984	-	99	84.915	Myotis_lucifugus
ENSG00000156697	UTP14A	100	80.595	ENSNGAG00000020390	Utp14a	99	80.595	Nannospalax_galili
ENSG00000156697	UTP14A	91	47.802	ENSNBRG00000016950	si:dkey-251i10.3	94	46.174	Neolamprologus_brichardi
ENSG00000156697	UTP14A	97	99.353	ENSNLEG00000015258	UTP14A	99	98.148	Nomascus_leucogenys
ENSG00000156697	UTP14A	97	64.078	ENSMEUG00000010177	-	89	73.404	Notamacropus_eugenii
ENSG00000156697	UTP14A	97	62.903	ENSOPRG00000007500	-	100	71.192	Ochotona_princeps
ENSG00000156697	UTP14A	99	80.959	ENSODEG00000011459	-	99	81.088	Octodon_degus
ENSG00000156697	UTP14A	92	47.521	ENSONIG00000020563	si:dkey-251i10.3	100	47.051	Oreochromis_niloticus
ENSG00000156697	UTP14A	98	59.326	ENSOANG00000013483	-	99	60.414	Ornithorhynchus_anatinus
ENSG00000156697	UTP14A	100	83.419	ENSOCUG00000016185	-	100	82.776	Oryctolagus_cuniculus
ENSG00000156697	UTP14A	94	49.355	ENSORLG00015003756	si:dkey-251i10.3	95	43.709	Oryzias_latipes_hsok
ENSG00000156697	UTP14A	62	63.959	ENSOMEG00000017220	si:dkey-251i10.3	91	48.387	Oryzias_melastigma
ENSG00000156697	UTP14A	99	83.787	ENSOGAG00000013228	-	100	83.139	Otolemur_garnettii
ENSG00000156697	UTP14A	99	78.210	ENSOARG00000012140	-	99	78.470	Ovis_aries
ENSG00000156697	UTP14A	100	78.663	ENSOARG00000015129	-	100	78.535	Ovis_aries
ENSG00000156697	UTP14A	100	99.481	ENSPPAG00000042440	UTP14A	100	99.481	Pan_paniscus
ENSG00000156697	UTP14A	99	89.392	ENSPPAG00000039808	UTP14C	99	88.616	Pan_paniscus
ENSG00000156697	UTP14A	100	85.694	ENSPPRG00000016925	-	100	85.694	Panthera_pardus
ENSG00000156697	UTP14A	100	85.556	ENSPTIG00000013011	-	100	85.556	Panthera_tigris_altaica
ENSG00000156697	UTP14A	99	89.521	ENSPTRG00000050996	UTP14C	99	88.745	Pan_troglodytes
ENSG00000156697	UTP14A	100	99.351	ENSPTRG00000022262	UTP14A	100	99.351	Pan_troglodytes
ENSG00000156697	UTP14A	99	90.402	ENSPANG00000004998	UTP14C	99	90.402	Papio_anubis
ENSG00000156697	UTP14A	100	97.280	ENSPANG00000010948	UTP14A	100	97.280	Papio_anubis
ENSG00000156697	UTP14A	80	58.846	ENSPMGG00000012734	si:dkey-251i10.3	97	45.049	Periophthalmus_magnuspinnatus
ENSG00000156697	UTP14A	100	78.784	ENSPEMG00000013553	Utp14a	100	78.784	Peromyscus_maniculatus_bairdii
ENSG00000156697	UTP14A	95	56.258	ENSPCIG00000027945	-	99	56.275	Phascolarctos_cinereus
ENSG00000156697	UTP14A	99	64.341	ENSPCIG00000015344	-	99	64.212	Phascolarctos_cinereus
ENSG00000156697	UTP14A	66	63.981	ENSPFOG00000020801	si:dkey-251i10.3	96	54.962	Poecilia_formosa
ENSG00000156697	UTP14A	83	57.407	ENSPREG00000015374	si:dkey-251i10.3	93	47.510	Poecilia_reticulata
ENSG00000156697	UTP14A	97	98.706	ENSPPYG00000020709	UTP14A	100	98.977	Pongo_abelii
ENSG00000156697	UTP14A	97	79.032	ENSPCAG00000006070	-	86	89.474	Procavia_capensis
ENSG00000156697	UTP14A	100	88.616	ENSPCOG00000017594	-	100	87.969	Propithecus_coquereli
ENSG00000156697	UTP14A	93	81.739	ENSPVAG00000017680	-	93	81.739	Pteropus_vampyrus
ENSG00000156697	UTP14A	91	48.383	ENSPNYG00000022865	si:dkey-251i10.3	90	47.043	Pundamilia_nyererei
ENSG00000156697	UTP14A	94	47.632	ENSPNAG00000000203	si:dkey-251i10.3	53	53.521	Pygocentrus_nattereri
ENSG00000156697	UTP14A	99	77.113	ENSRNOG00000005012	Utp14a	95	76.983	Rattus_norvegicus
ENSG00000156697	UTP14A	100	90.028	ENSRBIG00000038670	UTP14A	100	98.020	Rhinopithecus_bieti
ENSG00000156697	UTP14A	100	97.536	ENSRROG00000028678	UTP14A	100	97.536	Rhinopithecus_roxellana
ENSG00000156697	UTP14A	100	91.710	ENSSBOG00000017777	-	100	90.803	Saimiri_boliviensis_boliviensis
ENSG00000156697	UTP14A	100	93.750	ENSSBOG00000009039	-	100	92.778	Saimiri_boliviensis_boliviensis
ENSG00000156697	UTP14A	95	58.401	ENSSHAG00000015162	-	98	58.199	Sarcophilus_harrisii
ENSG00000156697	UTP14A	95	57.009	ENSSHAG00000002343	-	98	55.910	Sarcophilus_harrisii
ENSG00000156697	UTP14A	94	54.268	ENSSFOG00015010260	si:dkey-251i10.3	88	52.688	Scleropages_formosus
ENSG00000156697	UTP14A	92	48.087	ENSSMAG00000017825	si:dkey-251i10.3	95	47.908	Scophthalmus_maximus
ENSG00000156697	UTP14A	90	50.862	ENSSDUG00000000153	si:dkey-251i10.3	94	50.992	Seriola_dumerili
ENSG00000156697	UTP14A	96	49.533	ENSSLDG00000001899	si:dkey-251i10.3	97	50.267	Seriola_lalandi_dorsalis
ENSG00000156697	UTP14A	99	70.458	ENSSARG00000012854	-	99	70.535	Sorex_araneus
ENSG00000156697	UTP14A	95	70.740	ENSSARG00000006469	-	85	73.346	Sorex_araneus
ENSG00000156697	UTP14A	92	54.849	ENSSPUG00000003207	-	93	50.624	Sphenodon_punctatus
ENSG00000156697	UTP14A	92	48.431	ENSSPAG00000005656	si:dkey-251i10.3	93	48.837	Stegastes_partitus
ENSG00000156697	UTP14A	99	82.990	ENSSSCG00000012654	-	99	82.990	Sus_scrofa
ENSG00000156697	UTP14A	86	55.789	ENSTGUG00000005130	-	57	53.665	Taeniopygia_guttata
ENSG00000156697	UTP14A	65	62.802	ENSTRUG00000014271	si:dkey-251i10.3	57	49.885	Takifugu_rubripes
ENSG00000156697	UTP14A	66	58.491	ENSTNIG00000005975	si:dkey-251i10.3	86	52.381	Tetraodon_nigroviridis
ENSG00000156697	UTP14A	100	81.889	ENSTBEG00000000458	-	100	81.371	Tupaia_belangeri
ENSG00000156697	UTP14A	99	83.901	ENSTTRG00000003794	-	100	83.486	Tursiops_truncatus
ENSG00000156697	UTP14A	100	84.476	ENSUAMG00000001768	-	100	84.476	Ursus_americanus
ENSG00000156697	UTP14A	100	84.605	ENSUMAG00000004662	-	100	84.605	Ursus_maritimus
ENSG00000156697	UTP14A	100	84.994	ENSVPAG00000003129	-	100	84.994	Vicugna_pacos
ENSG00000156697	UTP14A	100	83.571	ENSVVUG00000008939	-	100	83.571	Vulpes_vulpes
ENSG00000156697	UTP14A	91	59.934	ENSXETG00000007465	utp14a	96	54.400	Xenopus_tropicalis
ENSG00000156697	UTP14A	90	48.232	ENSXCOG00000008430	si:dkey-251i10.3	57	53.790	Xiphophorus_couchianus
ENSG00000156697	UTP14A	83	56.667	ENSXMAG00000020072	si:dkey-251i10.3	56	52.204	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	15383276.21900206.23455924.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0032040	small-subunit processome	21873635.	IBA	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28672776	Human U3 protein 14a plays an anti-apoptotic role in cancer cells.	Biol Chem	2017 Oct 26	Ma T	doi: 10.1515/hsz-2017-0121.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chrX	129925108	Silent	novel	K554K	0.07
ACC	chrX	129919196	Missense_Mutation	novel	E187K	0.18	Utp14
BLCA	chrX	129907424	Missense_Mutation	NA	L28F	0.22	Utp14
BLCA	chrX	129908117	Missense_Mutation	novel	D54H	0.26	Utp14
BLCA	chrX	129925083	Missense_Mutation	NA	P546R	0.5
BLCA	chrX	129921609	Intron	novel		0.14
BLCA	chrX	129924916	Missense_Mutation	NA	E490D	0.27
BLCA	chrX	129921419	Missense_Mutation	novel	E394K	0.39
BLCA	chrX	129919400	Silent	NA	K221K	0.35
BLCA	chrX	129911909	Silent	novel	L175L	0.82
BLCA	chrX	129921456	Frame_Shift_Del	novel	S407*	0.11
BLCA	chrX	129921457	Frame_Shift_Ins	novel	*S407Cfs3**	0.11
BLCA	chrX	129908692	Missense_Mutation	novel	E66K	0.25	Utp14
BLCA	chrX	129906191	5'UTR	novel		0.26
BLCA	chrX	129924910	Silent	novel	Q488Q	0.73
BRCA	chrX	129924895	Silent	novel	T483T	0.07
BRCA	chrX	129929550	Missense_Mutation	NA	N753I	0.11
BRCA	chrX	129924962	Missense_Mutation	NA	E506K	0.35
BRCA	chrX	129925045	Silent	NA	L533L	0.11
BRCA	chrX	129924990	Missense_Mutation	NA	E515A	0.17
BRCA	chrX	129921417	Missense_Mutation	novel	P393L	0.08
BRCA	chrX	129926244	Missense_Mutation	NA	L650V	0.21
BRCA	chrX	129919407	Nonsense_Mutation	NA	R224*	0.32	Utp14
BRCA	chrX	129919427	Silent	NA	A230A	0.23
CESC	chrX	129908079	Missense_Mutation	novel	R41T	0.25	Utp14
CESC	chrX	129921340	Missense_Mutation	novel	M367I	0.36
CESC	chrX	129907424	Silent	NA	L28L	0.19
CESC	chrX	129925046	Missense_Mutation	NA	E534K	0.13
CESC	chrX	129913379	Intron	NA		0.29
CESC	chrX	129908107	Silent	NA	I50I	0.25
CESC	chrX	129921485	Missense_Mutation	novel	E416Q	0.84
COAD	chrX	129911142	Missense_Mutation	novel	I125F	0.21	Utp14
COAD	chrX	129925977	Missense_Mutation	novel	D603V	0.48
COAD	chrX	129924914	Missense_Mutation	novel	E490K	0.05
COAD	chrX	129920484	Missense_Mutation	NA	K260N	0.72	Utp14
COAD	chrX	129924811	Missense_Mutation	NA	E455D	0.1
COAD	chrX	129925160	Missense_Mutation	novel	V572M	0.41
COAD	chrX	129911834	Silent	novel	K150K	0.07
COAD	chrX	129919404	Nonsense_Mutation	novel	R223*	0.11	Utp14
COAD	chrX	129921741	Intron	novel		0.67
COAD	chrX	129924792	Splice_Region	novel		0.19
COAD	chrX	129911078	Silent	novel	V103V	0.31
COAD	chrX	129926253	Missense_Mutation	NA	A653T	0.17
GBM	chrX	129926320	Missense_Mutation	novel	I675N	0.32
GBM	chrX	129929386	Silent	novel	T698T	0.11
GBM	chrX	129908697	Silent	novel	A67A	0.9
GBM	chrX	129920503	Missense_Mutation	novel	E267K	0.12	Utp14
HNSC	chrX	129925926	Missense_Mutation	novel	E586G	0.61
HNSC	chrX	129929587	Silent	novel	L765L	0.78
HNSC	chrX	129929406	Missense_Mutation	novel	S705F	0.36
HNSC	chrX	129926011	Missense_Mutation	novel	E614D	0.75
HNSC	chrX	129929670	3'UTR	novel		0.35
HNSC	chrX	129925061	Missense_Mutation	novel	E539K	0.23
HNSC	chrX	129911087	Silent	novel	Q106Q	0.61
HNSC	chrX	129926000	Missense_Mutation	novel	E611K	0.18
HNSC	chrX	129919175	Missense_Mutation	novel	A180S	0.27	Utp14
KIRC	chrX	129929477	Missense_Mutation	NA	I729L	0.07
KIRC	chrX	129921684	Intron	novel		0.14
KIRC	chrX	129924877	Frame_Shift_Ins	novel	*I484Mfs38**	0.07
KIRP	chrX	129924841	Silent	novel	Q465Q	0.54
KIRP	chrX	129911768	Splice_Region	NA	I128I	0.62
KIRP	chrX	129929625	3'UTR	novel		0.71
LGG	chrX	129926275	Missense_Mutation	novel	K660I	0.38
LGG	chrX	129908718	Silent	novel	F74F	0.04
LGG	chrX	129919483	Frame_Shift_Del	novel	*S249Ifs8**	0.12	Utp14
LIHC	chrX	129925045	Missense_Mutation	novel	L533F	0.14
LUAD	chrX	129925197	Splice_Site	NA	X583_splice	0.24
LUAD	chrX	129929335	Splice_Site	NA	X682_splice	0.27
LUAD	chrX	129926272	Frame_Shift_Del	novel	*R659Kfs9**	0.2
LUAD	chrX	129921537	Missense_Mutation	NA	R433I	0.48
LUAD	chrX	129921290	Missense_Mutation	novel	E351K	0.15
LUAD	chrX	129920719	Silent	NA	K307K	0.07
LUAD	chrX	129921521	Silent	NA	R428R	0.29
LUAD	chrX	129929449	Silent	NA	P719P	0.15
LUAD	chrX	129924887	Missense_Mutation	novel	E481Q	0.2
LUAD	chrX	129926337	Nonsense_Mutation	novel	Q681*	0.07
LUAD	chrX	129919186	Silent	novel	P183P	0.06
LUAD	chrX	129906213	Translation_Start_Site	NA	M1?	0.13
LUAD	chrX	129921611	Intron	novel		0.34
LUAD	chrX	129929464	Silent	rs775408652	K724K	0.35
LUAD	chrX	129906199	5'UTR	NA		0.26
LUAD	chrX	129925082	Missense_Mutation	NA	P546S	0.17
LUAD	chrX	129924962	Missense_Mutation	NA	E506K	0.05
LUAD	chrX	129926065	Silent	NA	G632G	0.13
LUAD	chrX	129921459	Missense_Mutation	novel	S407I	0.44
LUAD	chrX	129925037	Missense_Mutation	novel	P531T	0.33
LUAD	chrX	129929646	3'UTR	novel		0.35
LUAD	chrX	129919186	Silent	novel	P183P	0.28
LUSC	chrX	129907419	Missense_Mutation	novel	L27F	0.74	Utp14
LUSC	chrX	129924857	Missense_Mutation	novel	H471Y	0.11
LUSC	chrX	129911844	Missense_Mutation	novel	A154P	0.06	Utp14
LUSC	chrX	129925158	Missense_Mutation	novel	S571F	0.47
LUSC	chrX	129929495	Missense_Mutation	novel	E735Q	0.19
LUSC	chrX	129919215	Missense_Mutation	novel	H193R	0.21	Utp14
LUSC	chrX	129925055	Missense_Mutation	NA	Q537K	0.17
LUSC	chrX	129921564	Missense_Mutation	NA	P442Q	0.07
LUSC	chrX	129925975	Silent	novel	D602D	0.28
LUSC	chrX	129929420	Nonsense_Mutation	NA	Q710*	0.23
LUSC	chrX	129907395	Silent	novel	L19L	0.09
LUSC	chrX	129919273	Silent	NA	L212L	0.68
LUSC	chrX	129926078	Missense_Mutation	novel	V637L	0.17
LUSC	chrX	129924833	Silent	NA	L463L	0.24
LUSC	chrX	129925972	Silent	NA	G601G	0.2
OV	chrX	129907364	Splice_Region	NA		0.32
OV	chrX	129919478	Silent	novel	I247I	0.11
OV	chrX	129919455	Missense_Mutation	novel	K240E	0.08	Utp14
OV	chrX	129924891	Missense_Mutation	novel	G482V	0.09
OV	chrX	129920509	Nonsense_Mutation	NA	E269*	0.4	Utp14
OV	chrX	129929607	Nonstop_Mutation	NA	772Sext21	0.28
OV	chrX	129921651	Intron	novel		0.53
PAAD	chrX	129911796	Missense_Mutation	rs150155910	A138T	0.23	Utp14
PAAD	chrX	129926284	Missense_Mutation	novel	N663S	0.28
READ	chrX	129929684	3'UTR	novel		0.05
READ	chrX	129929685	3'UTR	novel		0.05
READ	chrX	129926065	Silent	NA	G632G	0.17
READ	chrX	129920518	Missense_Mutation	rs759581297	R272W	0.8	Utp14
SKCM	chrX	129929485	Silent	NA	P731P	0.25
SKCM	chrX	129924868	Silent	NA	R474R	0.25
SKCM	chrX	129926083	Silent	novel	G638G	0.3
SKCM	chrX	129926084	Silent	novel	L639L	0.3
SKCM	chrX	129925958	Missense_Mutation	novel	E597K	0.08
SKCM	chrX	129911027	Silent	NA	V86V	0.9
SKCM	chrX	129911794	Missense_Mutation	NA	T137I	0.49	Utp14
SKCM	chrX	129925178	Missense_Mutation	NA	P578S	0.24
SKCM	chrX	129919200	Missense_Mutation	NA	I188S	0.36	Utp14
SKCM	chrX	129921620	Intron	novel		0.32
SKCM	chrX	129919213	Silent	NA	L192L	0.8
STAD	chrX	129921446	Missense_Mutation	NA	G403R	0.37
STAD	chrX	129907413	Missense_Mutation	NA	D25H	0.18	Utp14
STAD	chrX	129921463	Missense_Mutation	novel	E408D	0.25
STAD	chrX	129926289	Missense_Mutation	NA	P665S	0.57
STAD	chrX	129926289	Missense_Mutation	NA	P665S	0.43
STAD	chrX	129921510	Missense_Mutation	NA	F424C	0.15
STAD	chrX	129920525	Missense_Mutation	NA	V274A	0.2	Utp14
STAD	chrX	129908724	Silent	NA	V76V	0.87
STAD	chrX	129919469	Missense_Mutation	novel	E244D	0.16	Utp14
STAD	chrX	129926254	Missense_Mutation	NA	A653V	0.07
STAD	chrX	129921415	Missense_Mutation	NA	D392E	0.34
STAD	chrX	129919485	Missense_Mutation	NA	K250E	0.19	Utp14
TGCT	chrX	129926038	Silent	rs144234509	D623D	0.4
THYM	chrX	129919263	Missense_Mutation	novel	K209R	0.06	Utp14
UCEC	chrX	129926325	Missense_Mutation	NA	A677T	0.59
UCEC	chrX	129911041	Missense_Mutation	novel	L91P	0.22	Utp14
UCEC	chrX	129925080	Missense_Mutation	rs199650206	R545H	0.26
UCEC	chrX	129906210	5'UTR	novel		0.28
UCEC	chrX	129925962	Missense_Mutation	NA	A598D	0.44
UCEC	chrX	129929402	Nonsense_Mutation	NA	G704*	0.44
UCEC	chrX	129929713	3'UTR	novel		0.63
UCEC	chrX	129911796	Missense_Mutation	rs150155910	A138T	0.35	Utp14
UCEC	chrX	129925032	Missense_Mutation	novel	P529H	0.39
UCEC	chrX	129925132	Missense_Mutation	novel	Q562H	0.34
UCEC	chrX	129926065	Silent	NA	G632G	0.44
UCEC	chrX	129929576	Missense_Mutation	novel	K762Q	0.29
UCEC	chrX	129925993	Missense_Mutation	NA	F608L	0.12
UCEC	chrX	129919179	Missense_Mutation	NA	R181I	0.21	Utp14
UCEC	chrX	129929376	Missense_Mutation	NA	F695S	0.25
UCEC	chrX	129911795	Silent	rs745419974	T137T	0.09
UCEC	chrX	129906180	5'Flank	novel		0.19
UCEC	chrX	129921544	Silent	novel	E435E	0.19
UCEC	chrX	129921702	Intron	novel		0.25
UCEC	chrX	129924811	Missense_Mutation	NA	E455D	0.19
UCEC	chrX	129925047	Missense_Mutation	novel	E534A	0.4
UCEC	chrX	129919275	Missense_Mutation	rs370007411	R213Q	0.34	Utp14
UCEC	chrX	129921329	Missense_Mutation	novel	E364K	0.4
UCEC	chrX	129921614	Intron	novel		0.45
UCEC	chrX	129925993	Missense_Mutation	NA	F608L	0.29
UCEC	chrX	129907368	Missense_Mutation	novel	L10I	0.32	Utp14
UCEC	chrX	129908103	Missense_Mutation	novel	A49E	0.24	Utp14
UCEC	chrX	129924989	Missense_Mutation	novel	E515K	0.31
UCEC	chrX	129907380	Missense_Mutation	novel	S14G	0.52	Utp14
UCEC	chrX	129921244	Silent	novel	Q335Q	0.36
UCEC	chrX	129920706	Missense_Mutation	novel	G303E	0.37
UCEC	chrX	129925004	Nonsense_Mutation	NA	E520*	0.49
UCEC	chrX	129907413	Missense_Mutation	novel	D25Y	0.11	Utp14
UCEC	chrX	129926254	Missense_Mutation	NA	A653V	0.35
UCEC	chrX	129925065	Missense_Mutation	novel	R540M	0.58
UCEC	chrX	129925988	Missense_Mutation	novel	D607Y	0.47
UCEC	chrX	129919179	Missense_Mutation	NA	R181I	0.47	Utp14
UCEC	chrX	129907381	Missense_Mutation	NA	S14N	0.4	Utp14
UCEC	chrX	129920679	Missense_Mutation	NA	R294I	0.34	Utp14
UCEC	chrX	129921476	Missense_Mutation	NA	P413S	0.32
UCEC	chrX	129921293	Missense_Mutation	NA	D352Y	0.26
UCEC	chrX	129920679	Missense_Mutation	novel	R294K	0.37	Utp14
UCEC	chrX	129924940	Missense_Mutation	novel	E498D	0.27
UCEC	chrX	129907428	Missense_Mutation	novel	E30K	0.18	Utp14
UCEC	chrX	129926277	Missense_Mutation	novel	D661Y	0.14
UCEC	chrX	129921441	Missense_Mutation	novel	A401V	0.23
UCEC	chrX	129906218	Missense_Mutation	NA	A3V	0.67
UCEC	chrX	129911907	Missense_Mutation	novel	L175I	0.21	Utp14
UCEC	chrX	129929406	Missense_Mutation	novel	S705F	0.13
UCEC	chrX	129929579	Missense_Mutation	novel	K763Q	0.51
UCEC	chrX	129925031	Missense_Mutation	novel	P529T	0.26
UCEC	chrX	129920529	Silent	novel	N275N	0.04
UCEC	chrX	129911836	Missense_Mutation	novel	N151S	0.36	Utp14
UCEC	chrX	129921353	Missense_Mutation	novel	P372S	0.48
UCEC	chrX	129921336	Missense_Mutation	novel	Q366R	0.05
UCEC	chrX	129929706	3'UTR	novel		0.43
UCEC	chrX	129911138	Silent	novel	E123E	0.26
UCEC	chrX	129921269	Nonsense_Mutation	NA	E344*	0.22
UCEC	chrX	129911052	Missense_Mutation	novel	K95Q	0.08	Utp14
UCEC	chrX	129921534	Missense_Mutation	NA	K432T	0.39
UCEC	chrX	129925004	Nonsense_Mutation	NA	E520*	0.39
UCEC	chrX	129921534	Missense_Mutation	NA	K432I	0.42
UCEC	chrX	129929741	3'UTR	novel		0.58
UCEC	chrX	129906218	Missense_Mutation	NA	A3V	0.39
UCEC	chrX	129920505	Missense_Mutation	NA	E267D	0.36	Utp14
UCEC	chrX	129921277	Missense_Mutation	NA	E346D	0.3
UCEC	chrX	129911896	Missense_Mutation	novel	I171S	0.27	Utp14
UCEC	chrX	129926106	Missense_Mutation	novel	R646I	0.04
UCEC	chrX	129929558	Nonsense_Mutation	novel	R756*	0.05
UCEC	chrX	129925993	Missense_Mutation	NA	F608L	0.34
UCEC	chrX	129907408	Frame_Shift_Ins	novel	*D25Rfs6**	0.36	Utp14
UCEC	chrX	129929711	3'UTR	novel		0.35
UCEC	chrX	129925074	Missense_Mutation	novel	N543T	0.28
UCEC	chrX	129926112	Missense_Mutation	novel	R648Q	0.35
UCS	chrX	129919179	Missense_Mutation	NA	R181I	0.35	Utp14

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	AMP	0.0833	0.24013
KIRC	AMP	0.0284	0.12739
TGCT	DEL	0.0667	0.08422
THCA	DEL	0	0.21991
UCS	DEL	0.3036	0.063955

Survival Analysis

Cancer	P-value	Q-value
UCS	0.044	Kaplan-Meier Survival Analysis
HNSC	0.0012	Kaplan-Meier Survival Analysis
PRAD	0.02	Kaplan-Meier Survival Analysis
ESCA	0.0099	Kaplan-Meier Survival Analysis
KIRP	0.0001	Kaplan-Meier Survival Analysis
UCEC	0.0084	Kaplan-Meier Survival Analysis
LIHC	0.0026	Kaplan-Meier Survival Analysis
LGG	0.019	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742