EuRBPDB

Description

Ensembl ID: ENSG00000156983 (Gene tree)
Gene ID: 7862
Gene Symbol: BRPF1
Alias: BR140
Full Name: bromodomain and PHD finger containing 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 16,290 bases
Position: chr3:9,731,729-9,748,018
Accession: 14255
RBP type: non-canonical RBP
Summary: This gene encodes a bromodomain, PHD finger and chromo/Tudor-related Pro-Trp-Trp-Pro (PWWP) domain containing protein. The encoded protein is a component of the MOZ/MORF histone acetyltransferase complexes which function as a transcriptional regulators. This protein binds to the catalytic MYST domains of the MOZ and MORF proteins and may play a role in stimulating acetyltransferase and transcriptional activity of the complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000457855	BRPF1-206	4308	XM_011534101	ENSP00000410210	1214 (aa)	XP_011532403	P55201
ENST00000424362	BRPF1-203	4712	XM_005265449	ENSP00000398863	1213 (aa)	XP_005265506	P55201
ENST00000426583	BRPF1-204	534	-	ENSP00000404235	105 (aa)	-	C9JHC0
ENST00000383829	BRPF1-201	4736	XM_005265450	ENSP00000373340	1220 (aa)	XP_005265507	P55201
ENST00000433861	BRPF1-205	4304	XM_024453744	ENSP00000402485	1119 (aa)	XP_024309512	P55201
ENST00000420291	BRPF1-202	860	-	ENSP00000416728	100 (aa)	-	C9JDK5
ENST00000469066	BRPF1-207	431	-	-	- (aa)	-	-
ENST00000497565	BRPF1-208	689	-	-	- (aa)	-	-

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	-	IEA	Function
GO:0005515	protein binding	25281266.	IPI	Function
GO:0005634	nucleus	18794358.27939640.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	27939640.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0043966	histone H3 acetylation	16387653.	IDA	Process
GO:0043972	histone H3-K23 acetylation	27939640.	IMP	Process
GO:0043994	histone acetyltransferase activity (H3-K23 specific)	27939640.	IDA	Function
GO:0045893	positive regulation of transcription, DNA-templated	18794358.	IDA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0070776	MOZ/MORF histone acetyltransferase complex	16387653.18794358.27939640.	IDA	Component
GO:1901796	regulation of signal transduction by p53 class mediator	-	TAS	Process