EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000156990 (Gene tree)
Gene ID: 285367
Gene Symbol: RPUSD3
Alias: MGC29784
Full Name: RNA pseudouridine synthase D3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 6,754 bases
Position: chr3:9,837,849-9,844,602
Accession: 28437
RBP type: canonical RBP
Summary: This gene encodes a protein that functions in the assembly of the mitochondrial ribosome by adding a pseudouridine group to 16S rRNA. Loss of this gene results in causes defects in mitochondrial protein production. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000373331	PseudoU_synth_2	PF00849.22	1.5e-19	1	1
ENSP00000415616	PseudoU_synth_2	PF00849.22	3.2e-19	1	1
ENSP00000408693	PseudoU_synth_2	PF00849.22	3.3e-18	1	1
ENSP00000398921	PseudoU_synth_2	PF00849.22	4.3e-15	1	1
ENSP00000400397	PseudoU_synth_2	PF00849.22	2.6e-12	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000460909	RPUSD3-210	578	-	-	- (aa)	-	-
ENST00000473522	RPUSD3-214	547	-	-	- (aa)	-	-
ENST00000451405	RPUSD3-209	817	-	ENSP00000395492	36 (aa)	-	H7C0K9
ENST00000383820	RPUSD3-201	1225	XM_024453471	ENSP00000373331	351 (aa)	XP_024309239	Q6P087
ENST00000433555	RPUSD3-207	807	-	ENSP00000396405	102 (aa)	-	H7C0R9
ENST00000466141	RPUSD3-212	996	-	-	- (aa)	-	-
ENST00000423108	RPUSD3-203	756	-	ENSP00000405054	144 (aa)	-	H7C2C3
ENST00000485705	RPUSD3-217	630	-	-	- (aa)	-	-
ENST00000433535	RPUSD3-206	1178	-	ENSP00000398921	336 (aa)	-	Q6P087
ENST00000475470	RPUSD3-215	2413	-	-	- (aa)	-	-
ENST00000484134	RPUSD3-216	2491	-	-	- (aa)	-	-
ENST00000472381	RPUSD3-213	823	-	-	- (aa)	-	-
ENST00000427174	RPUSD3-205	907	-	ENSP00000400397	280 (aa)	-	H7C1H7
ENST00000464783	RPUSD3-211	1149	-	-	- (aa)	-	-
ENST00000424438	RPUSD3-204	1005	-	ENSP00000408693	212 (aa)	-	C9JM75
ENST00000433972	RPUSD3-208	1178	-	ENSP00000395446	151 (aa)	-	H7C0K7
ENST00000418713	RPUSD3-202	955	XM_024453472	ENSP00000415616	246 (aa)	XP_024309240	H7C454

Gene Model

Click here to download ENSG00000156990's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000156990's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000156990	RPUSD3	100	80.682	ENSAMEG00000016227	RPUSD3	100	80.682	Ailuropoda_melanoleuca
ENSG00000156990	RPUSD3	94	51.351	ENSACAG00000009836	RPUSD3	93	51.351	Anolis_carolinensis
ENSG00000156990	RPUSD3	99	81.340	ENSANAG00000038118	-	98	81.340	Aotus_nancymaae
ENSG00000156990	RPUSD3	99	66.507	ENSANAG00000007127	-	100	66.507	Aotus_nancymaae
ENSG00000156990	RPUSD3	91	88.601	ENSANAG00000019945	-	79	88.832	Aotus_nancymaae
ENSG00000156990	RPUSD3	98	81.395	ENSBTAG00000007968	RPUSD3	100	81.395	Bos_taurus
ENSG00000156990	RPUSD3	100	80.398	ENSCAFG00000029733	RPUSD3	100	80.398	Canis_familiaris
ENSG00000156990	RPUSD3	100	80.398	ENSCAFG00020008582	RPUSD3	100	80.398	Canis_lupus_dingo
ENSG00000156990	RPUSD3	98	80.814	ENSCHIG00000026027	RPUSD3	100	80.814	Capra_hircus
ENSG00000156990	RPUSD3	99	80.597	ENSTSYG00000009994	RPUSD3	100	80.597	Carlito_syrichta
ENSG00000156990	RPUSD3	82	79.661	ENSCAPG00000017559	RPUSD3	98	80.769	Cavia_aperea
ENSG00000156990	RPUSD3	98	68.116	ENSCPOG00000037956	RPUSD3	91	68.116	Cavia_porcellus
ENSG00000156990	RPUSD3	100	90.566	ENSCCAG00000029530	RPUSD3	100	90.566	Cebus_capucinus
ENSG00000156990	RPUSD3	100	93.868	ENSCATG00000036939	RPUSD3	100	93.868	Cercocebus_atys
ENSG00000156990	RPUSD3	100	91.738	ENSCSAG00000010506	RPUSD3	100	91.738	Chlorocebus_sabaeus
ENSG00000156990	RPUSD3	53	85.714	ENSCHOG00000010151	-	67	85.714	Choloepus_hoffmanni
ENSG00000156990	RPUSD3	82	57.143	ENSCPBG00000008825	RPUSD3	95	53.307	Chrysemys_picta_bellii
ENSG00000156990	RPUSD3	100	93.396	ENSCANG00000040711	RPUSD3	100	93.396	Colobus_angolensis_palliatus
ENSG00000156990	RPUSD3	99	72.334	ENSCGRG00001004923	Rpusd3	96	72.334	Cricetulus_griseus_chok1gshd
ENSG00000156990	RPUSD3	95	73.887	ENSCGRG00000018315	Rpusd3	98	73.887	Cricetulus_griseus_crigri
ENSG00000156990	RPUSD3	99	77.077	ENSDNOG00000039160	RPUSD3	92	77.077	Dasypus_novemcinctus
ENSG00000156990	RPUSD3	97	64.565	ENSDORG00000026827	Rpusd3	92	78.731	Dipodomys_ordii
ENSG00000156990	RPUSD3	100	73.011	ENSETEG00000006538	RPUSD3	99	73.011	Echinops_telfairi
ENSG00000156990	RPUSD3	81	37.931	ENSEBUG00000015605	RPUSD3	67	40.291	Eptatretus_burgeri
ENSG00000156990	RPUSD3	99	81.662	ENSEASG00005014160	RPUSD3	97	81.662	Equus_asinus_asinus
ENSG00000156990	RPUSD3	99	82.521	ENSECAG00000019988	RPUSD3	97	82.521	Equus_caballus
ENSG00000156990	RPUSD3	86	74.194	ENSEEUG00000007353	RPUSD3	96	57.817	Erinaceus_europaeus
ENSG00000156990	RPUSD3	100	81.250	ENSFCAG00000014199	RPUSD3	100	81.250	Felis_catus
ENSG00000156990	RPUSD3	77	50.916	ENSFALG00000012968	RPUSD3	99	48.352	Ficedula_albicollis
ENSG00000156990	RPUSD3	82	81.356	ENSFDAG00000008350	RPUSD3	91	75.920	Fukomys_damarensis
ENSG00000156990	RPUSD3	82	57.143	ENSGAGG00000007493	RPUSD3	82	53.232	Gopherus_agassizii
ENSG00000156990	RPUSD3	100	99.057	ENSGGOG00000013120	RPUSD3	100	99.057	Gorilla_gorilla
ENSG00000156990	RPUSD3	98	71.564	ENSHGLG00000011722	RPUSD3	96	67.112	Heterocephalus_glaber_female
ENSG00000156990	RPUSD3	98	71.564	ENSHGLG00100016038	RPUSD3	96	67.112	Heterocephalus_glaber_male
ENSG00000156990	RPUSD3	95	81.683	ENSSTOG00000002125	RPUSD3	99	77.650	Ictidomys_tridecemlineatus
ENSG00000156990	RPUSD3	95	74.272	ENSJJAG00000012679	Rpusd3	99	73.235	Jaculus_jaculus
ENSG00000156990	RPUSD3	98	81.105	ENSLAFG00000017501	RPUSD3	100	81.105	Loxodonta_africana
ENSG00000156990	RPUSD3	100	92.308	ENSMFAG00000032407	RPUSD3	100	92.308	Macaca_fascicularis
ENSG00000156990	RPUSD3	100	92.262	ENSMMUG00000010628	RPUSD3	100	92.262	Macaca_mulatta
ENSG00000156990	RPUSD3	100	92.023	ENSMNEG00000040308	RPUSD3	100	92.023	Macaca_nemestrina
ENSG00000156990	RPUSD3	100	94.340	ENSMLEG00000033940	RPUSD3	100	94.340	Mandrillus_leucophaeus
ENSG00000156990	RPUSD3	94	75.821	ENSMAUG00000015473	Rpusd3	97	75.821	Mesocricetus_auratus
ENSG00000156990	RPUSD3	99	82.938	ENSMICG00000002315	RPUSD3	100	81.977	Microcebus_murinus
ENSG00000156990	RPUSD3	97	72.727	ENSMOCG00000022613	Rpusd3	99	72.727	Microtus_ochrogaster
ENSG00000156990	RPUSD3	96	55.394	ENSMODG00000005210	RPUSD3	89	55.394	Monodelphis_domestica
ENSG00000156990	RPUSD3	98	72.384	MGP_CAROLIEiJ_G0028725	Rpusd3	100	72.384	Mus_caroli
ENSG00000156990	RPUSD3	98	72.674	ENSMUSG00000051169	Rpusd3	100	72.674	Mus_musculus
ENSG00000156990	RPUSD3	98	73.256	MGP_PahariEiJ_G0022476	Rpusd3	100	73.256	Mus_pahari
ENSG00000156990	RPUSD3	98	72.384	MGP_SPRETEiJ_G0029753	Rpusd3	100	72.384	Mus_spretus
ENSG00000156990	RPUSD3	99	79.370	ENSMPUG00000017132	RPUSD3	99	79.370	Mustela_putorius_furo
ENSG00000156990	RPUSD3	97	84.257	ENSMLUG00000006135	RPUSD3	99	84.257	Myotis_lucifugus
ENSG00000156990	RPUSD3	95	75.075	ENSNGAG00000023704	Rpusd3	97	75.075	Nannospalax_galili
ENSG00000156990	RPUSD3	100	97.170	ENSNLEG00000004214	RPUSD3	100	97.170	Nomascus_leucogenys
ENSG00000156990	RPUSD3	82	63.866	ENSMEUG00000013098	-	100	67.050	Notamacropus_eugenii
ENSG00000156990	RPUSD3	96	64.307	ENSOPRG00000002300	RPUSD3	99	63.506	Ochotona_princeps
ENSG00000156990	RPUSD3	85	73.984	ENSODEG00000018137	RPUSD3	90	78.544	Octodon_degus
ENSG00000156990	RPUSD3	84	53.371	ENSOANG00000012081	-	100	51.916	Ornithorhynchus_anatinus
ENSG00000156990	RPUSD3	95	74.359	ENSOCUG00000027885	RPUSD3	99	69.164	Oryctolagus_cuniculus
ENSG00000156990	RPUSD3	95	84.236	ENSOGAG00000012592	RPUSD3	100	85.032	Otolemur_garnettii
ENSG00000156990	RPUSD3	99	81.481	ENSOARG00000005928	RPUSD3	99	81.481	Ovis_aries
ENSG00000156990	RPUSD3	100	98.006	ENSPPAG00000038083	RPUSD3	100	98.006	Pan_paniscus
ENSG00000156990	RPUSD3	100	81.250	ENSPPRG00000024433	RPUSD3	100	81.250	Panthera_pardus
ENSG00000156990	RPUSD3	100	81.899	ENSPTIG00000006828	RPUSD3	100	82.267	Panthera_tigris_altaica
ENSG00000156990	RPUSD3	100	98.113	ENSPTRG00000051760	RPUSD3	100	98.113	Pan_troglodytes
ENSG00000156990	RPUSD3	100	94.340	ENSPANG00000023885	RPUSD3	100	94.340	Papio_anubis
ENSG00000156990	RPUSD3	95	73.824	ENSPEMG00000017245	Rpusd3	99	73.824	Peromyscus_maniculatus_bairdii
ENSG00000156990	RPUSD3	96	58.702	ENSPCIG00000021901	RPUSD3	97	58.702	Phascolarctos_cinereus
ENSG00000156990	RPUSD3	100	96.011	ENSPPYG00000013676	RPUSD3	100	96.011	Pongo_abelii
ENSG00000156990	RPUSD3	81	82.759	ENSPCAG00000013731	-	100	60.554	Procavia_capensis
ENSG00000156990	RPUSD3	100	86.364	ENSPCOG00000018314	RPUSD3	100	86.364	Propithecus_coquereli
ENSG00000156990	RPUSD3	100	80.114	ENSPVAG00000011107	RPUSD3	100	80.114	Pteropus_vampyrus
ENSG00000156990	RPUSD3	98	71.429	ENSRNOG00000009084	Rpusd3	100	71.429	Rattus_norvegicus
ENSG00000156990	RPUSD3	100	94.340	ENSRBIG00000041230	RPUSD3	100	94.340	Rhinopithecus_bieti
ENSG00000156990	RPUSD3	100	94.340	ENSRROG00000043328	RPUSD3	100	94.340	Rhinopithecus_roxellana
ENSG00000156990	RPUSD3	100	88.604	ENSSBOG00000036106	RPUSD3	100	88.604	Saimiri_boliviensis_boliviensis
ENSG00000156990	RPUSD3	95	57.426	ENSSHAG00000015536	RPUSD3	99	59.355	Sarcophilus_harrisii
ENSG00000156990	RPUSD3	100	80.966	ENSSSCG00000011555	RPUSD3	100	80.966	Sus_scrofa
ENSG00000156990	RPUSD3	82	50.000	ENSTGUG00000008744	RPUSD3	93	52.074	Taeniopygia_guttata
ENSG00000156990	RPUSD3	95	79.703	ENSTBEG00000000176	RPUSD3	100	77.509	Tupaia_belangeri
ENSG00000156990	RPUSD3	100	80.398	ENSTTRG00000007544	RPUSD3	100	80.398	Tursiops_truncatus
ENSG00000156990	RPUSD3	96	81.951	ENSUAMG00000011354	RPUSD3	98	81.847	Ursus_americanus
ENSG00000156990	RPUSD3	100	79.830	ENSUMAG00000018830	RPUSD3	100	79.830	Ursus_maritimus
ENSG00000156990	RPUSD3	99	82.075	ENSVVUG00000023735	RPUSD3	100	81.686	Vulpes_vulpes
ENSG00000156990	RPUSD3	85	48.000	ENSXETG00000023546	rpusd3	99	50.178	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001522	pseudouridine synthesis	-	IEA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005759	mitochondrial matrix	-	IEA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0009982	pseudouridine synthase activity	-	IEA	Function
GO:0070131	positive regulation of mitochondrial translation	27667664.	IMP	Process