EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000158526 (Gene tree)
Gene ID: 90121
Gene Symbol: TSR2
Alias: DT1P1A10|RP1-112K5.2|WGG1
Full Name: TSR2 ribosome maturation factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 5,087 bases
Position: chrX:54,440,401-54,445,487
Accession: 25455
RBP type: canonical RBP
Summary: The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia. [provided by RefSeq, Oct 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000364293	WGG	PF10273.9	7.4e-25	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000375151	TSR2-201	1534	-	ENSP00000364293	191 (aa)	-	Q969E8

Gene Model

Click here to download ENSG00000158526's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000158526's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000158526	TSR2	91	43.429	ENSAPOG00000004150	-	90	42.373	Acanthochromis_polyacanthus
ENSG00000158526	TSR2	100	86.387	ENSAMEG00000002469	TSR2	100	85.340	Ailuropoda_melanoleuca
ENSG00000158526	TSR2	70	50.365	ENSACIG00000004880	tsr2	88	52.756	Amphilophus_citrinellus
ENSG00000158526	TSR2	100	47.396	ENSAOCG00000015893	tsr2	97	46.354	Amphiprion_ocellaris
ENSG00000158526	TSR2	100	45.833	ENSAPEG00000023549	tsr2	97	45.833	Amphiprion_percula
ENSG00000158526	TSR2	100	44.503	ENSATEG00000019009	-	100	44.503	Anabas_testudineus
ENSG00000158526	TSR2	100	51.813	ENSACAG00000012270	TSR2	100	51.813	Anolis_carolinensis
ENSG00000158526	TSR2	100	94.241	ENSANAG00000000062	TSR2	100	94.241	Aotus_nancymaae
ENSG00000158526	TSR2	100	43.455	ENSACLG00000014269	tsr2	100	43.455	Astatotilapia_calliptera
ENSG00000158526	TSR2	100	49.223	ENSAMXG00000016817	tsr2	89	46.632	Astyanax_mexicanus
ENSG00000158526	TSR2	100	87.435	ENSBTAG00000015858	TSR2	99	84.817	Bos_taurus
ENSG00000158526	TSR2	94	71.508	ENSBTAG00000018311	-	98	67.956	Bos_taurus
ENSG00000158526	TSR2	100	93.194	ENSCJAG00000000251	TSR2	100	93.194	Callithrix_jacchus
ENSG00000158526	TSR2	100	87.435	ENSCAFG00000016440	TSR2	100	86.387	Canis_familiaris
ENSG00000158526	TSR2	100	87.435	ENSCAFG00020014044	TSR2	100	86.387	Canis_lupus_dingo
ENSG00000158526	TSR2	92	71.186	ENSCHIG00000009963	-	92	68.362	Capra_hircus
ENSG00000158526	TSR2	95	79.558	ENSTSYG00000031644	-	99	79.558	Carlito_syrichta
ENSG00000158526	TSR2	100	86.911	ENSTSYG00000005670	-	100	85.864	Carlito_syrichta
ENSG00000158526	TSR2	100	75.393	ENSTSYG00000031321	-	100	75.393	Carlito_syrichta
ENSG00000158526	TSR2	100	84.293	ENSCPOG00000033139	TSR2	99	84.293	Cavia_porcellus
ENSG00000158526	TSR2	100	92.670	ENSCCAG00000025421	TSR2	100	92.670	Cebus_capucinus
ENSG00000158526	TSR2	100	98.429	ENSCATG00000036868	-	100	98.429	Cercocebus_atys
ENSG00000158526	TSR2	100	94.241	ENSCATG00000045152	-	99	94.241	Cercocebus_atys
ENSG00000158526	TSR2	100	87.435	ENSCLAG00000007235	TSR2	99	87.435	Chinchilla_lanigera
ENSG00000158526	TSR2	100	94.241	ENSCSAG00000000402	-	100	94.241	Chlorocebus_sabaeus
ENSG00000158526	TSR2	97	96.216	ENSCSAG00000012366	-	97	96.216	Chlorocebus_sabaeus
ENSG00000158526	TSR2	100	90.576	ENSCHOG00000001068	TSR2	100	90.576	Choloepus_hoffmanni
ENSG00000158526	TSR2	100	33.333	ENSCING00000002386	-	63	37.398	Ciona_intestinalis
ENSG00000158526	TSR2	96	31.250	ENSCSAVG00000009298	-	53	39.216	Ciona_savignyi
ENSG00000158526	TSR2	100	85.340	ENSCANG00000036773	-	97	85.340	Colobus_angolensis_palliatus
ENSG00000158526	TSR2	100	97.906	ENSCANG00000043156	-	100	97.906	Colobus_angolensis_palliatus
ENSG00000158526	TSR2	100	82.199	ENSCGRG00001023321	Tsr2	99	82.199	Cricetulus_griseus_chok1gshd
ENSG00000158526	TSR2	100	80.928	ENSCGRG00000010855	Tsr2	99	80.928	Cricetulus_griseus_crigri
ENSG00000158526	TSR2	98	40.000	ENSCSEG00000017003	tsr2	99	40.526	Cynoglossus_semilaevis
ENSG00000158526	TSR2	99	44.974	ENSCVAG00000001845	tsr2	99	47.090	Cyprinodon_variegatus
ENSG00000158526	TSR2	100	43.979	ENSDARG00000005772	tsr2	98	52.101	Danio_rerio
ENSG00000158526	TSR2	100	81.675	ENSDORG00000025574	Tsr2	99	81.152	Dipodomys_ordii
ENSG00000158526	TSR2	100	85.417	ENSETEG00000018510	TSR2	100	84.896	Echinops_telfairi
ENSG00000158526	TSR2	95	40.217	ENSEBUG00000012895	tsr2	92	40.217	Eptatretus_burgeri
ENSG00000158526	TSR2	100	89.005	ENSEASG00005013005	TSR2	99	85.864	Equus_asinus_asinus
ENSG00000158526	TSR2	100	88.482	ENSECAG00000029844	TSR2	86	85.340	Equus_caballus
ENSG00000158526	TSR2	99	41.053	ENSELUG00000007768	tsr2	97	41.304	Esox_lucius
ENSG00000158526	TSR2	100	88.482	ENSFCAG00000002226	TSR2	100	87.435	Felis_catus
ENSG00000158526	TSR2	100	81.152	ENSFDAG00000011554	TSR2	99	81.152	Fukomys_damarensis
ENSG00000158526	TSR2	92	42.045	ENSGACG00000000595	tsr2	97	40.642	Gasterosteus_aculeatus
ENSG00000158526	TSR2	67	57.031	ENSGAGG00000007629	TSR2	70	57.031	Gopherus_agassizii
ENSG00000158526	TSR2	100	100.000	ENSGGOG00000041368	TSR2	100	100.000	Gorilla_gorilla
ENSG00000158526	TSR2	100	43.455	ENSHBUG00000020989	tsr2	80	45.026	Haplochromis_burtoni
ENSG00000158526	TSR2	100	82.199	ENSHGLG00000002188	TSR2	99	82.199	Heterocephalus_glaber_female
ENSG00000158526	TSR2	100	82.199	ENSHGLG00100001234	TSR2	99	82.199	Heterocephalus_glaber_male
ENSG00000158526	TSR2	69	48.148	ENSHCOG00000017585	-	59	51.200	Hippocampus_comes
ENSG00000158526	TSR2	100	44.560	ENSIPUG00000012170	tsr2	100	44.560	Ictalurus_punctatus
ENSG00000158526	TSR2	100	90.052	ENSSTOG00000033612	TSR2	99	90.052	Ictidomys_tridecemlineatus
ENSG00000158526	TSR2	100	81.443	ENSJJAG00000004561	Tsr2	99	81.443	Jaculus_jaculus
ENSG00000158526	TSR2	99	44.737	ENSKMAG00000012611	-	97	46.196	Kryptolebias_marmoratus
ENSG00000158526	TSR2	100	87.958	ENSLAFG00000018093	TSR2	99	87.958	Loxodonta_africana
ENSG00000158526	TSR2	100	98.429	ENSMFAG00000001364	TSR2	100	98.429	Macaca_fascicularis
ENSG00000158526	TSR2	100	98.429	ENSMMUG00000012612	TSR2	100	98.429	Macaca_mulatta
ENSG00000158526	TSR2	100	94.764	ENSMMUG00000010044	-	100	94.764	Macaca_mulatta
ENSG00000158526	TSR2	100	98.429	ENSMNEG00000041996	TSR2	100	98.429	Macaca_nemestrina
ENSG00000158526	TSR2	100	98.429	ENSMLEG00000032632	TSR2	100	98.429	Mandrillus_leucophaeus
ENSG00000158526	TSR2	100	43.455	ENSMAMG00000011540	tsr2	100	42.408	Mastacembelus_armatus
ENSG00000158526	TSR2	100	43.455	ENSMZEG00005026752	tsr2	100	43.455	Maylandia_zebra
ENSG00000158526	TSR2	100	84.536	ENSMAUG00000012389	Tsr2	99	84.536	Mesocricetus_auratus
ENSG00000158526	TSR2	100	89.529	ENSMICG00000010116	TSR2	99	89.529	Microcebus_murinus
ENSG00000158526	TSR2	100	80.105	ENSMOCG00000006662	Tsr2	99	80.105	Microtus_ochrogaster
ENSG00000158526	TSR2	98	37.037	ENSMMOG00000009751	-	100	35.052	Mola_mola
ENSG00000158526	TSR2	100	45.128	ENSMODG00000020894	-	100	44.615	Monodelphis_domestica
ENSG00000158526	TSR2	96	43.478	ENSMALG00000014552	tsr2	96	42.935	Monopterus_albus
ENSG00000158526	TSR2	100	85.864	MGP_CAROLIEiJ_G0033491	Tsr2	99	85.864	Mus_caroli
ENSG00000158526	TSR2	100	85.864	ENSMUSG00000025264	Tsr2	99	85.864	Mus_musculus
ENSG00000158526	TSR2	100	84.293	MGP_PahariEiJ_G0032030	Tsr2	99	84.293	Mus_pahari
ENSG00000158526	TSR2	100	85.864	MGP_SPRETEiJ_G0034661	Tsr2	99	85.864	Mus_spretus
ENSG00000158526	TSR2	100	87.435	ENSMPUG00000011436	TSR2	100	86.387	Mustela_putorius_furo
ENSG00000158526	TSR2	97	81.818	ENSMLUG00000010613	TSR2	97	81.283	Myotis_lucifugus
ENSG00000158526	TSR2	100	84.293	ENSNGAG00000021351	Tsr2	99	84.293	Nannospalax_galili
ENSG00000158526	TSR2	96	45.109	ENSNBRG00000007965	tsr2	97	45.109	Neolamprologus_brichardi
ENSG00000158526	TSR2	100	99.476	ENSNLEG00000030041	TSR2	100	99.476	Nomascus_leucogenys
ENSG00000158526	TSR2	53	60.784	ENSMEUG00000000188	-	100	45.732	Notamacropus_eugenii
ENSG00000158526	TSR2	58	54.054	ENSMEUG00000006729	-	83	55.340	Notamacropus_eugenii
ENSG00000158526	TSR2	66	80.315	ENSOPRG00000016595	TSR2	87	80.180	Ochotona_princeps
ENSG00000158526	TSR2	100	83.505	ENSODEG00000000542	-	99	83.505	Octodon_degus
ENSG00000158526	TSR2	93	78.531	ENSODEG00000019951	-	100	78.531	Octodon_degus
ENSG00000158526	TSR2	95	84.066	ENSODEG00000014931	-	99	84.066	Octodon_degus
ENSG00000158526	TSR2	100	43.979	ENSONIG00000000763	tsr2	100	43.979	Oreochromis_niloticus
ENSG00000158526	TSR2	69	71.212	ENSOANG00000000707	TSR2	90	72.656	Ornithorhynchus_anatinus
ENSG00000158526	TSR2	100	89.529	ENSOCUG00000027678	-	100	89.529	Oryctolagus_cuniculus
ENSG00000158526	TSR2	86	87.349	ENSOCUG00000014714	-	100	87.349	Oryctolagus_cuniculus
ENSG00000158526	TSR2	96	45.109	ENSORLG00000022662	tsr2	97	45.109	Oryzias_latipes
ENSG00000158526	TSR2	96	44.022	ENSORLG00020003033	tsr2	97	45.109	Oryzias_latipes_hni
ENSG00000158526	TSR2	96	45.109	ENSORLG00015017253	tsr2	97	45.109	Oryzias_latipes_hsok
ENSG00000158526	TSR2	100	43.455	ENSOMEG00000011483	tsr2	100	43.455	Oryzias_melastigma
ENSG00000158526	TSR2	100	42.932	ENSOMEG00000013975	-	100	43.979	Oryzias_melastigma
ENSG00000158526	TSR2	100	84.817	ENSOGAG00000003468	TSR2	100	84.817	Otolemur_garnettii
ENSG00000158526	TSR2	89	67.647	ENSOARG00000009487	-	97	63.429	Ovis_aries
ENSG00000158526	TSR2	100	88.482	ENSOARG00000006467	-	99	85.864	Ovis_aries
ENSG00000158526	TSR2	100	100.000	ENSPPAG00000021242	TSR2	100	100.000	Pan_paniscus
ENSG00000158526	TSR2	100	88.482	ENSPPRG00000001337	TSR2	100	87.435	Panthera_pardus
ENSG00000158526	TSR2	100	87.958	ENSPTIG00000007138	TSR2	99	86.911	Panthera_tigris_altaica
ENSG00000158526	TSR2	100	100.000	ENSPTRG00000045904	TSR2	100	100.000	Pan_troglodytes
ENSG00000158526	TSR2	95	92.857	ENSPANG00000002291	-	98	92.857	Papio_anubis
ENSG00000158526	TSR2	100	98.429	ENSPANG00000008042	-	100	98.429	Papio_anubis
ENSG00000158526	TSR2	100	39.267	ENSPKIG00000023676	tsr2	100	40.306	Paramormyrops_kingsleyae
ENSG00000158526	TSR2	100	34.694	ENSPMGG00000002963	tsr2	100	37.113	Periophthalmus_magnuspinnatus
ENSG00000158526	TSR2	100	82.199	ENSPEMG00000015713	Tsr2	99	82.199	Peromyscus_maniculatus_bairdii
ENSG00000158526	TSR2	95	41.711	ENSPMAG00000001705	tsr2	92	42.246	Petromyzon_marinus
ENSG00000158526	TSR2	100	50.500	ENSPCIG00000024314	-	95	50.000	Phascolarctos_cinereus
ENSG00000158526	TSR2	99	43.005	ENSPFOG00000011824	tsr2	99	42.347	Poecilia_formosa
ENSG00000158526	TSR2	99	43.915	ENSPLAG00000023520	tsr2	99	43.229	Poecilia_latipinna
ENSG00000158526	TSR2	99	44.792	ENSPMEG00000000360	tsr2	99	44.792	Poecilia_mexicana
ENSG00000158526	TSR2	99	43.915	ENSPREG00000013009	tsr2	99	44.271	Poecilia_reticulata
ENSG00000158526	TSR2	100	100.000	ENSPPYG00000020381	-	72	100.000	Pongo_abelii
ENSG00000158526	TSR2	100	87.435	ENSPCOG00000002354	TSR2	100	87.435	Propithecus_coquereli
ENSG00000158526	TSR2	64	85.366	ENSPVAG00000000034	TSR2	88	87.850	Pteropus_vampyrus
ENSG00000158526	TSR2	100	43.455	ENSPNYG00000019995	tsr2	80	45.026	Pundamilia_nyererei
ENSG00000158526	TSR2	100	45.550	ENSPNAG00000024167	tsr2	100	45.550	Pygocentrus_nattereri
ENSG00000158526	TSR2	100	86.911	ENSRNOG00000002556	NEWGENE_1562416	99	86.911	Rattus_norvegicus
ENSG00000158526	TSR2	100	98.429	ENSRBIG00000024521	-	100	98.429	Rhinopithecus_bieti
ENSG00000158526	TSR2	100	90.052	ENSRBIG00000003999	-	89	90.052	Rhinopithecus_bieti
ENSG00000158526	TSR2	100	90.052	ENSRROG00000033469	-	92	90.052	Rhinopithecus_roxellana
ENSG00000158526	TSR2	100	98.429	ENSRROG00000029439	-	100	98.429	Rhinopithecus_roxellana
ENSG00000158526	TSR2	100	93.717	ENSSBOG00000019737	TSR2	100	93.717	Saimiri_boliviensis_boliviensis
ENSG00000158526	TSR2	86	51.515	ENSSHAG00000004824	-	99	51.515	Sarcophilus_harrisii
ENSG00000158526	TSR2	100	42.932	ENSSFOG00015002207	tsr2	100	43.719	Scleropages_formosus
ENSG00000158526	TSR2	100	44.330	ENSSMAG00000012882	tsr2	100	42.784	Scophthalmus_maximus
ENSG00000158526	TSR2	100	44.792	ENSSDUG00000019445	tsr2	100	44.271	Seriola_dumerili
ENSG00000158526	TSR2	100	43.979	ENSSLDG00000005598	tsr2	100	44.792	Seriola_lalandi_dorsalis
ENSG00000158526	TSR2	100	46.907	ENSSPUG00000019286	TSR2	99	47.644	Sphenodon_punctatus
ENSG00000158526	TSR2	100	85.340	ENSSSCG00000012334	TSR2	100	85.340	Sus_scrofa
ENSG00000158526	TSR2	95	42.935	ENSTRUG00000008947	tsr2	97	41.711	Takifugu_rubripes
ENSG00000158526	TSR2	90	38.857	ENSTNIG00000002173	-	99	38.286	Tetraodon_nigroviridis
ENSG00000158526	TSR2	69	90.840	ENSTBEG00000016242	TSR2	89	90.840	Tupaia_belangeri
ENSG00000158526	TSR2	100	71.728	ENSTTRG00000003274	TSR2	100	69.110	Tursiops_truncatus
ENSG00000158526	TSR2	100	84.021	ENSUAMG00000009605	TSR2	100	81.771	Ursus_americanus
ENSG00000158526	TSR2	100	84.021	ENSUMAG00000019189	TSR2	100	81.771	Ursus_maritimus
ENSG00000158526	TSR2	94	80.000	ENSVPAG00000007532	TSR2	100	80.000	Vicugna_pacos
ENSG00000158526	TSR2	100	83.505	ENSVVUG00000002247	TSR2	99	81.250	Vulpes_vulpes
ENSG00000158526	TSR2	100	41.117	ENSXETG00000033574	TSR2	99	41.624	Xenopus_tropicalis
ENSG00000158526	TSR2	99	43.915	ENSXMAG00000024827	tsr2	90	42.708	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0005515	protein binding	16189514.19060904.20562859.25416956.	IPI	Function