EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000159409 (Gene tree)
Gene ID: 11189
Gene Symbol: CELF3
Alias: CAGH4|BRUNOL1|ERDA4|MGC57297|TNRC4
Full Name: CUGBP Elav-like family member 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 16,770 bases
Position: chr1:151,700,052-151,716,821
Accession: 11967
RBP type: canonical RBP
Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000290585	RRM_1	PF00076.22	1.9e-53	1	3
ENSP00000290585	RRM_1	PF00076.22	1.9e-53	2	3
ENSP00000290585	RRM_1	PF00076.22	1.9e-53	3	3
ENSP00000290583	RRM_1	PF00076.22	3.2e-53	1	3
ENSP00000290583	RRM_1	PF00076.22	3.2e-53	2	3
ENSP00000290583	RRM_1	PF00076.22	3.2e-53	3	3
ENSP00000402503	RRM_1	PF00076.22	9.7e-51	1	3
ENSP00000402503	RRM_1	PF00076.22	9.7e-51	2	3
ENSP00000402503	RRM_1	PF00076.22	9.7e-51	3	3

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29981323	Alternative RNA splicing associated with axon regeneration after rat peripheral nerve injury.	Exp Neurol	2018 Oct	Mao S	doi: 10.1016/j.expneurol.2018.07.003
30597088	Convergent Evidence That ZNF804A Is a Regulator of Pre-messenger RNA Processing and Gene Expression.	Schizophr Bull	2018 Dec 29	Chapman RM	doi: 10.1093/schbul/sby183
10556089	ETR-1, a homologue of a protein linked to myotonic dystrophy, is essential for muscle development in Caenorhabditis elegans.	Curr Biol	1999 Nov 4	Milne CA	-
15593335	Comparison of the expression patterns of five neural RNA binding proteins in the Xenopus retina.	J Comp Neurol	2005 Jan 24	Amato MA	-
17725984	Expression, localization and tau exon 10 splicing activity of the brain RNA-binding protein TNRC4.	Hum Mol Genet	2007 Nov 15	Chapple JP	-
17393433	Mice deficient for RNA-binding protein brunol1 show reduction of spermatogenesis but are fertile.	Mol Reprod Dev	2007 Nov	Dev A	-
25145264	Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1.	Genes Cells	2014 Sep	Ishizuka A	doi: 10.1111/gtc.12169.
28648844	Novel functions for the RNA-binding protein ETR-1 in Caenorhabditis elegans reproduction and engulfment of germline apoptotic cell corpses.	Dev Biol	2017 Sep 1	Boateng R	doi: 10.1016/j.ydbio.2017.06.015

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000290583	CELF3-201	3246	XM_006711139	ENSP00000290583	465 (aa)	XP_006711202	Q5SZQ8
ENST00000478829	CELF3-206	733	-	-	- (aa)	-	-
ENST00000290585	CELF3-202	2335	XM_011509111	ENSP00000290585	415 (aa)	XP_011507413	Q5SZQ8
ENST00000479893	CELF3-207	731	-	-	- (aa)	-	-
ENST00000419910	CELF3-203	684	-	-	- (aa)	-	-
ENST00000420342	CELF3-204	2444	-	ENSP00000402503	466 (aa)	-	H0Y623
ENST00000470688	CELF3-205	2970	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000159409's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000159409's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000159409	CELF3	100	65.618	ENSG00000101489	CELF4	99	97.561
ENSG00000159409	CELF3	89	55.191	ENSG00000149187	CELF1	97	44.512
ENSG00000159409	CELF3	98	35.632	ENSG00000066044	ELAVL1	93	44.444
ENSG00000159409	CELF3	61	35.000	ENSG00000153250	RBMS1	63	35.000
ENSG00000159409	CELF3	100	65.310	ENSG00000161082	CELF5	92	66.026
ENSG00000159409	CELF3	61	40.741	ENSG00000162374	ELAVL4	71	40.741
ENSG00000159409	CELF3	94	39.474	ENSG00000144642	RBMS3	78	38.961
ENSG00000159409	CELF3	98	35.632	ENSG00000196361	ELAVL3	70	41.975
ENSG00000159409	CELF3	100	68.240	ENSG00000140488	CELF6	100	61.026
ENSG00000159409	CELF3	53	35.616	ENSG00000174740	PABPC5	69	35.616
ENSG00000159409	CELF3	92	35.616	ENSG00000101104	PABPC1L	59	35.616
ENSG00000159409	CELF3	69	35.714	ENSG00000090621	PABPC4	73	31.111
ENSG00000159409	CELF3	77	83.333	ENSG00000048740	CELF2	94	83.333
ENSG00000159409	CELF3	66	35.616	ENSG00000070756	PABPC1	67	36.585
ENSG00000159409	CELF3	69	34.091	ENSG00000151923	TIAL1	73	37.333
ENSG00000159409	CELF3	76	32.500	ENSG00000076067	RBMS2	72	32.500
ENSG00000159409	CELF3	79	33.684	ENSG00000179950	PUF60	61	37.500
ENSG00000159409	CELF3	74	37.805	ENSG00000116001	TIA1	89	44.000
ENSG00000159409	CELF3	63	41.975	ENSG00000107105	ELAVL2	89	41.975

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000159409	CELF3	100	80.556	ENSAPOG00000006015	celf3a	100	80.556	Acanthochromis_polyacanthus
ENSG00000159409	CELF3	100	70.299	ENSAPOG00000000910	celf3b	100	70.299	Acanthochromis_polyacanthus
ENSG00000159409	CELF3	99	96.567	ENSAMEG00000000509	CELF3	100	96.567	Ailuropoda_melanoleuca
ENSG00000159409	CELF3	100	82.692	ENSACIG00000007698	celf3b	100	82.692	Amphilophus_citrinellus
ENSG00000159409	CELF3	100	77.137	ENSACIG00000010932	celf3a	100	77.137	Amphilophus_citrinellus
ENSG00000159409	CELF3	100	80.342	ENSAOCG00000020552	celf3a	100	80.342	Amphiprion_ocellaris
ENSG00000159409	CELF3	100	85.783	ENSAOCG00000007824	celf3b	100	85.783	Amphiprion_ocellaris
ENSG00000159409	CELF3	100	80.342	ENSAPEG00000008728	celf3a	100	80.342	Amphiprion_percula
ENSG00000159409	CELF3	100	80.215	ENSAPEG00000007642	celf3b	100	80.215	Amphiprion_percula
ENSG00000159409	CELF3	100	79.915	ENSATEG00000008884	celf3a	100	78.708	Anabas_testudineus
ENSG00000159409	CELF3	100	79.487	ENSATEG00000023560	celf3b	100	79.487	Anabas_testudineus
ENSG00000159409	CELF3	98	60.533	ENSACAG00000016959	-	100	61.008	Anolis_carolinensis
ENSG00000159409	CELF3	100	96.774	ENSANAG00000030590	CELF3	100	96.774	Aotus_nancymaae
ENSG00000159409	CELF3	98	74.413	ENSACLG00000009631	celf3a	97	74.588	Astatotilapia_calliptera
ENSG00000159409	CELF3	100	82.265	ENSACLG00000020342	celf3b	100	82.265	Astatotilapia_calliptera
ENSG00000159409	CELF3	98	77.551	ENSAMXG00000012489	celf3b	100	77.551	Astyanax_mexicanus
ENSG00000159409	CELF3	98	77.806	ENSAMXG00000009926	celf3a	100	78.005	Astyanax_mexicanus
ENSG00000159409	CELF3	100	99.140	ENSBTAG00000019131	CELF3	100	99.140	Bos_taurus
ENSG00000159409	CELF3	72	65.282	ENSCJAG00000039430	-	72	64.306	Callithrix_jacchus
ENSG00000159409	CELF3	100	99.570	ENSCJAG00000007857	CELF3	100	99.570	Callithrix_jacchus
ENSG00000159409	CELF3	99	99.142	ENSCAFG00000012794	CELF3	86	99.142	Canis_familiaris
ENSG00000159409	CELF3	100	99.518	ENSCAFG00020009731	CELF3	100	99.518	Canis_lupus_dingo
ENSG00000159409	CELF3	100	98.925	ENSCHIG00000025847	CELF3	100	98.925	Capra_hircus
ENSG00000159409	CELF3	100	95.269	ENSTSYG00000033066	CELF3	100	95.269	Carlito_syrichta
ENSG00000159409	CELF3	100	78.587	ENSCAPG00000015341	CELF3	94	100.000	Cavia_aperea
ENSG00000159409	CELF3	100	99.518	ENSCPOG00000003539	CELF3	100	99.518	Cavia_porcellus
ENSG00000159409	CELF3	100	99.570	ENSCCAG00000024686	CELF3	100	99.570	Cebus_capucinus
ENSG00000159409	CELF3	100	100.000	ENSCATG00000030846	CELF3	100	100.000	Cercocebus_atys
ENSG00000159409	CELF3	98	61.159	ENSCATG00000044494	-	91	61.884	Cercocebus_atys
ENSG00000159409	CELF3	100	99.140	ENSCLAG00000000586	CELF3	100	99.140	Chinchilla_lanigera
ENSG00000159409	CELF3	84	100.000	ENSCSAG00000001812	CELF3	100	100.000	Chlorocebus_sabaeus
ENSG00000159409	CELF3	100	86.538	ENSCPBG00000008870	CELF3	100	86.538	Chrysemys_picta_bellii
ENSG00000159409	CELF3	100	99.785	ENSCANG00000038866	CELF3	100	99.785	Colobus_angolensis_palliatus
ENSG00000159409	CELF3	100	99.277	ENSCGRG00001019777	Celf3	100	99.277	Cricetulus_griseus_chok1gshd
ENSG00000159409	CELF3	84	59.391	ENSCGRG00001002551	Celf5	89	63.173	Cricetulus_griseus_chok1gshd
ENSG00000159409	CELF3	100	99.277	ENSCGRG00000015342	Celf3	100	99.277	Cricetulus_griseus_crigri
ENSG00000159409	CELF3	100	80.983	ENSCSEG00000007913	celf3a	100	80.983	Cynoglossus_semilaevis
ENSG00000159409	CELF3	100	81.356	ENSCSEG00000002581	celf3b	100	81.356	Cynoglossus_semilaevis
ENSG00000159409	CELF3	100	80.128	ENSCVAG00000018056	celf3a	100	80.128	Cyprinodon_variegatus
ENSG00000159409	CELF3	100	82.203	ENSCVAG00000009184	celf3b	100	82.203	Cyprinodon_variegatus
ENSG00000159409	CELF3	100	79.487	ENSDARG00000034668	celf3a	100	79.487	Danio_rerio
ENSG00000159409	CELF3	100	77.419	ENSDARG00000006983	celf3b	100	77.419	Danio_rerio
ENSG00000159409	CELF3	100	98.280	ENSDNOG00000041501	CELF3	100	98.280	Dasypus_novemcinctus
ENSG00000159409	CELF3	100	97.684	ENSDORG00000002488	Celf3	100	97.684	Dipodomys_ordii
ENSG00000159409	CELF3	100	100.000	ENSEASG00005005254	CELF3	100	100.000	Equus_asinus_asinus
ENSG00000159409	CELF3	100	96.989	ENSECAG00000020365	CELF3	100	100.000	Equus_caballus
ENSG00000159409	CELF3	77	91.358	ENSEEUG00000010622	CELF3	68	91.358	Erinaceus_europaeus
ENSG00000159409	CELF3	100	76.923	ENSELUG00000006121	celf3a	100	76.923	Esox_lucius
ENSG00000159409	CELF3	100	77.800	ENSELUG00000013477	celf3b	100	78.004	Esox_lucius
ENSG00000159409	CELF3	100	99.518	ENSFCAG00000007908	CELF3	100	99.518	Felis_catus
ENSG00000159409	CELF3	100	99.036	ENSFDAG00000011452	CELF3	100	99.036	Fukomys_damarensis
ENSG00000159409	CELF3	100	76.923	ENSFHEG00000012530	celf3a	100	76.923	Fundulus_heteroclitus
ENSG00000159409	CELF3	100	82.479	ENSFHEG00000021947	celf3b	100	82.479	Fundulus_heteroclitus
ENSG00000159409	CELF3	100	72.340	ENSGMOG00000006107	celf3b	99	72.340	Gadus_morhua
ENSG00000159409	CELF3	93	86.190	ENSGMOG00000002937	celf3a	100	68.026	Gadus_morhua
ENSG00000159409	CELF3	100	79.834	ENSGALG00000028478	CELF3	100	81.935	Gallus_gallus
ENSG00000159409	CELF3	100	82.203	ENSGAFG00000012731	celf3b	100	82.203	Gambusia_affinis
ENSG00000159409	CELF3	100	79.701	ENSGAFG00000004128	celf3a	100	79.701	Gambusia_affinis
ENSG00000159409	CELF3	100	81.489	ENSGACG00000011707	celf3b	99	81.489	Gasterosteus_aculeatus
ENSG00000159409	CELF3	100	77.991	ENSGACG00000003274	celf3a	100	77.991	Gasterosteus_aculeatus
ENSG00000159409	CELF3	100	80.128	ENSGAGG00000019676	CELF3	100	77.991	Gopherus_agassizii
ENSG00000159409	CELF3	100	99.759	ENSGGOG00000021973	-	100	99.759	Gorilla_gorilla
ENSG00000159409	CELF3	84	99.486	ENSGGOG00000023049	-	100	99.742	Gorilla_gorilla
ENSG00000159409	CELF3	98	63.158	ENSGGOG00000041211	CELF5	100	63.962	Gorilla_gorilla
ENSG00000159409	CELF3	100	80.556	ENSHBUG00000001061	celf3a	100	80.556	Haplochromis_burtoni
ENSG00000159409	CELF3	100	81.992	ENSHBUG00000003367	celf3b	100	81.992	Haplochromis_burtoni
ENSG00000159409	CELF3	100	99.570	ENSHGLG00000006045	CELF3	100	99.570	Heterocephalus_glaber_female
ENSG00000159409	CELF3	100	99.570	ENSHGLG00100008013	CELF3	100	99.570	Heterocephalus_glaber_male
ENSG00000159409	CELF3	98	78.500	ENSHCOG00000000397	celf3b	100	78.500	Hippocampus_comes
ENSG00000159409	CELF3	100	74.005	ENSHCOG00000005746	celf3a	100	74.005	Hippocampus_comes
ENSG00000159409	CELF3	100	79.487	ENSIPUG00000008218	celf3a	100	76.316	Ictalurus_punctatus
ENSG00000159409	CELF3	100	99.759	ENSSTOG00000022934	CELF3	100	99.759	Ictidomys_tridecemlineatus
ENSG00000159409	CELF3	100	98.798	ENSJJAG00000020104	Celf3	100	98.798	Jaculus_jaculus
ENSG00000159409	CELF3	72	64.179	ENSJJAG00000006902	Celf5	89	62.890	Jaculus_jaculus
ENSG00000159409	CELF3	100	77.137	ENSKMAG00000001269	celf3b	100	77.137	Kryptolebias_marmoratus
ENSG00000159409	CELF3	100	80.556	ENSKMAG00000011999	celf3a	100	80.556	Kryptolebias_marmoratus
ENSG00000159409	CELF3	100	73.504	ENSLBEG00000026936	celf3a	100	73.504	Labrus_bergylta
ENSG00000159409	CELF3	94	93.407	ENSLBEG00000026140	celf3b	100	82.265	Labrus_bergylta
ENSG00000159409	CELF3	100	86.325	ENSLACG00000002301	CELF3	100	86.325	Latimeria_chalumnae
ENSG00000159409	CELF3	98	83.838	ENSLOCG00000006518	celf3b	100	83.838	Lepisosteus_oculatus
ENSG00000159409	CELF3	100	88.372	ENSLAFG00000030147	CELF3	100	89.006	Loxodonta_africana
ENSG00000159409	CELF3	100	98.936	ENSMFAG00000040182	CELF3	100	98.936	Macaca_fascicularis
ENSG00000159409	CELF3	98	63.158	ENSMFAG00000022580	-	100	63.962	Macaca_fascicularis
ENSG00000159409	CELF3	98	62.053	ENSMMUG00000015513	-	90	61.337	Macaca_mulatta
ENSG00000159409	CELF3	100	98.810	ENSMMUG00000016952	CELF3	100	98.810	Macaca_mulatta
ENSG00000159409	CELF3	72	65.282	ENSMNEG00000001853	-	89	64.306	Macaca_nemestrina
ENSG00000159409	CELF3	100	98.936	ENSMNEG00000044120	CELF3	100	98.936	Macaca_nemestrina
ENSG00000159409	CELF3	100	99.785	ENSMLEG00000028006	CELF3	100	99.785	Mandrillus_leucophaeus
ENSG00000159409	CELF3	100	79.487	ENSMAMG00000001436	celf3a	100	76.282	Mastacembelus_armatus
ENSG00000159409	CELF3	100	81.780	ENSMAMG00000015079	celf3b	100	81.780	Mastacembelus_armatus
ENSG00000159409	CELF3	100	82.265	ENSMZEG00005016013	celf3b	100	82.265	Maylandia_zebra
ENSG00000159409	CELF3	100	80.342	ENSMZEG00005026501	celf3a	100	80.342	Maylandia_zebra
ENSG00000159409	CELF3	84	59.645	ENSMAUG00000020336	Celf5	89	63.456	Mesocricetus_auratus
ENSG00000159409	CELF3	100	99.355	ENSMAUG00000007850	Celf3	100	99.355	Mesocricetus_auratus
ENSG00000159409	CELF3	100	99.785	ENSMICG00000010644	CELF3	100	99.785	Microcebus_murinus
ENSG00000159409	CELF3	76	63.662	ENSMOCG00000005573	Celf5	89	63.636	Microtus_ochrogaster
ENSG00000159409	CELF3	100	99.041	ENSMOCG00000001878	Celf3	100	99.041	Microtus_ochrogaster
ENSG00000159409	CELF3	100	77.350	ENSMMOG00000015806	celf3a	100	76.596	Mola_mola
ENSG00000159409	CELF3	100	80.769	ENSMMOG00000016150	celf3b	100	80.769	Mola_mola
ENSG00000159409	CELF3	97	96.903	ENSMODG00000027673	CELF3	68	96.903	Monodelphis_domestica
ENSG00000159409	CELF3	98	58.568	ENSMODG00000019151	-	100	60.705	Monodelphis_domestica
ENSG00000159409	CELF3	100	78.147	ENSMALG00000011641	celf3a	100	78.147	Monopterus_albus
ENSG00000159409	CELF3	100	77.479	ENSMALG00000007438	celf3b	100	77.066	Monopterus_albus
ENSG00000159409	CELF3	100	99.518	MGP_CAROLIEiJ_G0025314	Celf3	100	99.518	Mus_caroli
ENSG00000159409	CELF3	76	63.662	ENSMUSG00000034818	Celf5	93	76.744	Mus_musculus
ENSG00000159409	CELF3	100	99.519	ENSMUSG00000028137	Celf3	100	99.567	Mus_musculus
ENSG00000159409	CELF3	100	99.043	MGP_PahariEiJ_G0026757	Celf3	100	99.567	Mus_pahari
ENSG00000159409	CELF3	100	64.957	MGP_SPRETEiJ_G0016461	Celf5	93	76.744	Mus_spretus
ENSG00000159409	CELF3	100	99.759	MGP_SPRETEiJ_G0026256	Celf3	100	99.759	Mus_spretus
ENSG00000159409	CELF3	99	98.934	ENSMPUG00000003617	CELF3	87	98.934	Mustela_putorius_furo
ENSG00000159409	CELF3	99	62.151	ENSMLUG00000002193	CELF3	100	62.151	Myotis_lucifugus
ENSG00000159409	CELF3	98	61.995	ENSMLUG00000006471	-	100	62.796	Myotis_lucifugus
ENSG00000159409	CELF3	100	98.807	ENSNGAG00000021612	Celf3	100	98.807	Nannospalax_galili
ENSG00000159409	CELF3	98	75.000	ENSNBRG00000017554	celf3a	100	75.000	Neolamprologus_brichardi
ENSG00000159409	CELF3	98	80.357	ENSNBRG00000003364	celf3b	100	80.357	Neolamprologus_brichardi
ENSG00000159409	CELF3	100	94.304	ENSNLEG00000010255	CELF3	100	94.304	Nomascus_leucogenys
ENSG00000159409	CELF3	100	59.062	ENSMEUG00000013080	-	92	59.701	Notamacropus_eugenii
ENSG00000159409	CELF3	98	71.239	ENSMEUG00000014562	CELF3	97	71.175	Notamacropus_eugenii
ENSG00000159409	CELF3	64	100.000	ENSOPRG00000011130	CELF3	54	100.000	Ochotona_princeps
ENSG00000159409	CELF3	100	99.518	ENSODEG00000010505	CELF3	100	99.518	Octodon_degus
ENSG00000159409	CELF3	100	81.607	ENSONIG00000006421	celf3b	100	81.607	Oreochromis_niloticus
ENSG00000159409	CELF3	100	80.983	ENSONIG00000019703	celf3a	100	80.983	Oreochromis_niloticus
ENSG00000159409	CELF3	51	86.813	ENSOANG00000004406	-	55	86.813	Ornithorhynchus_anatinus
ENSG00000159409	CELF3	100	99.785	ENSOCUG00000003551	CELF3	100	99.785	Oryctolagus_cuniculus
ENSG00000159409	CELF3	100	81.780	ENSORLG00000010447	celf3b	93	81.780	Oryzias_latipes
ENSG00000159409	CELF3	100	74.947	ENSORLG00000002630	celf3a	100	74.947	Oryzias_latipes
ENSG00000159409	CELF3	100	80.556	ENSORLG00020007978	celf3a	100	80.556	Oryzias_latipes_hni
ENSG00000159409	CELF3	100	81.780	ENSORLG00020008839	celf3b	100	81.780	Oryzias_latipes_hni
ENSG00000159409	CELF3	100	81.568	ENSORLG00015014818	celf3b	100	81.568	Oryzias_latipes_hsok
ENSG00000159409	CELF3	100	81.568	ENSOMEG00000009131	celf3b	100	81.568	Oryzias_melastigma
ENSG00000159409	CELF3	100	83.650	ENSOMEG00000007034	celf3a	100	80.769	Oryzias_melastigma
ENSG00000159409	CELF3	94	100.000	ENSOGAG00000001830	CELF3	79	100.000	Otolemur_garnettii
ENSG00000159409	CELF3	100	83.871	ENSOARG00000021028	CELF3	91	83.871	Ovis_aries
ENSG00000159409	CELF3	100	99.785	ENSPPAG00000038551	CELF3	100	99.785	Pan_paniscus
ENSG00000159409	CELF3	98	63.158	ENSPPAG00000029786	-	100	63.962	Pan_paniscus
ENSG00000159409	CELF3	100	99.759	ENSPPRG00000004600	CELF3	100	99.759	Panthera_pardus
ENSG00000159409	CELF3	97	99.592	ENSPTIG00000013450	CELF3	98	99.592	Panthera_tigris_altaica
ENSG00000159409	CELF3	100	99.759	ENSPTRG00000001293	CELF3	100	99.759	Pan_troglodytes
ENSG00000159409	CELF3	100	100.000	ENSPANG00000023526	CELF3	100	100.000	Papio_anubis
ENSG00000159409	CELF3	100	83.439	ENSPKIG00000010833	celf3a	100	83.864	Paramormyrops_kingsleyae
ENSG00000159409	CELF3	100	58.548	ENSPMGG00000014685	-	94	59.574	Periophthalmus_magnuspinnatus
ENSG00000159409	CELF3	98	80.867	ENSPMGG00000007794	celf3b	100	80.867	Periophthalmus_magnuspinnatus
ENSG00000159409	CELF3	100	76.709	ENSPMGG00000000921	celf3a	100	76.709	Periophthalmus_magnuspinnatus
ENSG00000159409	CELF3	76	63.483	ENSPEMG00000021763	Celf5	89	63.456	Peromyscus_maniculatus_bairdii
ENSG00000159409	CELF3	100	99.036	ENSPEMG00000001184	Celf3	100	99.036	Peromyscus_maniculatus_bairdii
ENSG00000159409	CELF3	98	97.270	ENSPCIG00000021190	CELF3	98	97.351	Phascolarctos_cinereus
ENSG00000159409	CELF3	100	80.342	ENSPFOG00000008507	celf3a	99	80.342	Poecilia_formosa
ENSG00000159409	CELF3	100	81.992	ENSPFOG00000013307	celf3b	100	81.992	Poecilia_formosa
ENSG00000159409	CELF3	98	69.307	ENSPLAG00000008490	celf3a	100	69.479	Poecilia_latipinna
ENSG00000159409	CELF3	100	81.992	ENSPLAG00000018202	celf3b	100	81.992	Poecilia_latipinna
ENSG00000159409	CELF3	98	66.667	ENSPMEG00000009389	-	100	66.667	Poecilia_mexicana
ENSG00000159409	CELF3	98	66.667	ENSPMEG00000011349	celf3a	100	66.667	Poecilia_mexicana
ENSG00000159409	CELF3	100	82.203	ENSPMEG00000023690	celf3b	100	82.203	Poecilia_mexicana
ENSG00000159409	CELF3	100	80.556	ENSPREG00000018923	celf3a	100	80.556	Poecilia_reticulata
ENSG00000159409	CELF3	100	84.689	ENSPREG00000017378	celf3b	100	84.689	Poecilia_reticulata
ENSG00000159409	CELF3	99	83.656	ENSPPYG00000000859	CELF3	100	84.731	Pongo_abelii
ENSG00000159409	CELF3	97	98.681	ENSPCAG00000001623	CELF3	100	98.681	Procavia_capensis
ENSG00000159409	CELF3	100	99.785	ENSPCOG00000004694	CELF3	100	99.785	Propithecus_coquereli
ENSG00000159409	CELF3	99	88.602	ENSPVAG00000015012	CELF3	100	88.602	Pteropus_vampyrus
ENSG00000159409	CELF3	100	77.564	ENSPNYG00000011518	celf3a	100	77.564	Pundamilia_nyererei
ENSG00000159409	CELF3	100	82.265	ENSPNYG00000004167	celf3b	100	82.265	Pundamilia_nyererei
ENSG00000159409	CELF3	100	81.710	ENSPNAG00000018005	celf3b	100	82.185	Pygocentrus_nattereri
ENSG00000159409	CELF3	100	79.487	ENSPNAG00000017276	celf3a	100	79.487	Pygocentrus_nattereri
ENSG00000159409	CELF3	100	98.309	ENSRNOG00000020875	Celf3	100	98.309	Rattus_norvegicus
ENSG00000159409	CELF3	76	62.360	ENSRNOG00000004695	Celf5	89	62.323	Rattus_norvegicus
ENSG00000159409	CELF3	100	89.293	ENSRBIG00000043205	CELF3	100	89.507	Rhinopithecus_bieti
ENSG00000159409	CELF3	100	99.785	ENSRROG00000044979	CELF3	100	99.785	Rhinopithecus_roxellana
ENSG00000159409	CELF3	100	99.140	ENSSBOG00000021984	CELF3	100	99.140	Saimiri_boliviensis_boliviensis
ENSG00000159409	CELF3	100	96.559	ENSSHAG00000015744	CELF3	100	96.559	Sarcophilus_harrisii
ENSG00000159409	CELF3	100	83.795	ENSSFOG00015022130	celf3a	84	83.795	Scleropages_formosus
ENSG00000159409	CELF3	100	76.709	ENSSMAG00000002478	celf3a	100	76.709	Scophthalmus_maximus
ENSG00000159409	CELF3	100	81.568	ENSSMAG00000015634	celf3b	100	81.568	Scophthalmus_maximus
ENSG00000159409	CELF3	100	76.709	ENSSDUG00000018695	celf3a	100	76.709	Seriola_dumerili
ENSG00000159409	CELF3	100	82.203	ENSSDUG00000007239	celf3b	100	82.203	Seriola_dumerili
ENSG00000159409	CELF3	100	82.203	ENSSLDG00000015302	celf3b	100	82.203	Seriola_lalandi_dorsalis
ENSG00000159409	CELF3	100	76.709	ENSSLDG00000013940	celf3a	100	76.709	Seriola_lalandi_dorsalis
ENSG00000159409	CELF3	100	63.636	ENSSPUG00000002462	CELF3	100	71.279	Sphenodon_punctatus
ENSG00000159409	CELF3	100	76.709	ENSSPAG00000003615	celf3a	100	76.709	Stegastes_partitus
ENSG00000159409	CELF3	100	85.167	ENSSPAG00000019028	celf3b	100	85.167	Stegastes_partitus
ENSG00000159409	CELF3	100	99.785	ENSSSCG00000006618	CELF3	100	99.785	Sus_scrofa
ENSG00000159409	CELF3	100	78.419	ENSTRUG00000014225	celf3b	100	77.991	Takifugu_rubripes
ENSG00000159409	CELF3	98	77.551	ENSTRUG00000012064	celf3a	100	77.749	Takifugu_rubripes
ENSG00000159409	CELF3	100	81.529	ENSTNIG00000008062	celf3b	100	81.356	Tetraodon_nigroviridis
ENSG00000159409	CELF3	100	72.211	ENSTNIG00000017546	celf3a	99	72.211	Tetraodon_nigroviridis
ENSG00000159409	CELF3	98	88.946	ENSTBEG00000010130	CELF3	100	88.432	Tupaia_belangeri
ENSG00000159409	CELF3	91	97.400	ENSTTRG00000009835	CELF3	100	97.400	Tursiops_truncatus
ENSG00000159409	CELF3	100	99.356	ENSUAMG00000019567	CELF3	100	99.356	Ursus_americanus
ENSG00000159409	CELF3	98	60.382	ENSUMAG00000007241	-	88	61.140	Ursus_maritimus
ENSG00000159409	CELF3	100	89.398	ENSUMAG00000001772	CELF3	100	89.126	Ursus_maritimus
ENSG00000159409	CELF3	71	100.000	ENSVPAG00000000661	CELF3	65	100.000	Vicugna_pacos
ENSG00000159409	CELF3	72	99.675	ENSVVUG00000013080	CELF3	74	99.675	Vulpes_vulpes
ENSG00000159409	CELF3	50	93.478	ENSXETG00000012296	celf3	99	93.478	Xenopus_tropicalis
ENSG00000159409	CELF3	100	52.795	ENSXETG00000021745	-	100	52.929	Xenopus_tropicalis
ENSG00000159409	CELF3	100	76.282	ENSXCOG00000019737	celf3a	100	76.282	Xiphophorus_couchianus
ENSG00000159409	CELF3	100	55.269	ENSXCOG00000009514	-	87	56.236	Xiphophorus_couchianus
ENSG00000159409	CELF3	100	71.581	ENSXCOG00000019503	celf3b	90	71.581	Xiphophorus_couchianus
ENSG00000159409	CELF3	100	80.128	ENSXMAG00000014619	celf3a	100	80.128	Xiphophorus_maculatus
ENSG00000159409	CELF3	100	82.415	ENSXMAG00000016475	celf3b	100	82.415	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	11158314.	IDA	Process
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003723	RNA binding	17725984.	IMP	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	17725984.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	17725984.	IDA	Component
GO:0006376	mRNA splice site selection	21873635.	IBA	Process
GO:0007283	spermatogenesis	-	IEA	Process
GO:0008380	RNA splicing	17725984.	IMP	Process
GO:0016604	nuclear body	-	IEA	Component
GO:0030317	flagellated sperm motility	-	IEA	Process
GO:0030575	nuclear body organization	-	IEA	Process
GO:0036002	pre-mRNA binding	11158314.	NAS	Function
GO:0048026	positive regulation of mRNA splicing, via spliceosome	15009664.	IDA	Process
GO:0097322	7SK snRNA binding	-	IEA	Function
GO:0098781	ncRNA transcription	-	IEA	Process
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	151709244	Missense_Mutation	rs770229986	R128W	0.29
BLCA	chr1	151705852	Missense_Mutation	NA	D414N	0.57	RRM_1
BLCA	chr1	151709280	Missense_Mutation	novel	E116Q	0.07
BLCA	chr1	151705852	Missense_Mutation	NA	D414N	0.3	RRM_1
BLCA	chr1	151706229	Missense_Mutation	novel	R374T	0.16
BLCA	chr1	151709788	Missense_Mutation	novel	N78Y	0.28
BLCA	chr1	151709789	Missense_Mutation	novel	M77I	0.27
BRCA	chr1	151702656	3'UTR	novel		0.11
BRCA	chr1	151705940	Missense_Mutation	NA	I384M	0.24	RRM_1
BRCA	chr1	151709072	Missense_Mutation	NA	A138T	0.04
CESC	chr1	151703328	3'UTR	novel		0.08
CESC	chr1	151709008	Missense_Mutation	NA	R159Q	0.19
CESC	chr1	151705100	Missense_Mutation	novel	G447S	0.25	RRM_1
CESC	chr1	151714436	Intron	novel		0.17
CESC	chr1	151709262	Missense_Mutation	rs774349768	D122N	0.21
CESC	chr1	151709267	Missense_Mutation	novel	T120N	0.23
CESC	chr1	151707183	Missense_Mutation	novel	P295H	0.2
CHOL	chr1	151714623	Missense_Mutation	rs754604007	A67T	0.8
COAD	chr1	151705907	Missense_Mutation	novel	E395D	0.26	RRM_1
COAD	chr1	151707165	Missense_Mutation	rs746263623	N301S	0.4
COAD	chr1	151705091	Missense_Mutation	novel	R450C	0.23	RRM_1
COAD	chr1	151716026	5'UTR	rs574081772		0.38
COAD	chr1	151706249	Silent	NA	Q367Q	0.29
COAD	chr1	151709073	Silent	rs778927541	C137C	0.46
COAD	chr1	151706270	Silent	novel	Q360Q	0.17
COAD	chr1	151705927	Frame_Shift_Del	novel	*Q389Rfs38**	0.16	RRM_1
COAD	chr1	151709018	Missense_Mutation	NA	H156N	0.34
COAD	chr1	151707887	Nonsense_Mutation	novel	R179*	0.13
COAD	chr1	151706724	Silent	NA	P311P	0.74
COAD	chr1	151707163	Missense_Mutation	rs779202939	G302R	0.23
ESCA	chr1	151707221	Nonsense_Mutation	novel	Y282*	0.16
GBM	chr1	151705070	Missense_Mutation	novel	R457W	0.13
HNSC	chr1	151705033	Splice_Region	novel		0.31
HNSC	chr1	151715952	Silent	novel	L23L	0.13
HNSC	chr1	151707896	Missense_Mutation	novel	E176Q	0.14
KIRC	chr1	151715996	Silent	NA	L9L	0.22
KIRP	chr1	151706690	Missense_Mutation	novel	A323T	0.43
KIRP	chr1	151715986	Missense_Mutation	NA	G12E	0.68
LAML	chr1	151705032	Splice_Region	novel		0.05
LGG	chr1	151705085	Missense_Mutation	novel	K452E	0.44	RRM_1
LIHC	chr1	151707859	Missense_Mutation	novel	A188D	0.18
LIHC	chr1	151716507	5'UTR	novel		0.13
LIHC	chr1	151716005	Missense_Mutation	NA	A6P	0.43
LIHC	chr1	151707226	Missense_Mutation	NA	G281S	0.14
LUAD	chr1	151709755	Missense_Mutation	NA	E89K	0.17
LUAD	chr1	151707921	Missense_Mutation	NA	S167R	0.15
LUAD	chr1	151709277	Missense_Mutation	novel	P117T	0.04
LUAD	chr1	151709292	Silent	novel	R112R	0.13
LUAD	chr1	151709075	Missense_Mutation	NA	C137S	0.15
LUAD	chr1	151705070	Silent	NA	R457R	0.4
LUSC	chr1	151715979	Silent	novel	I14I	0.23
LUSC	chr1	151707912	Silent	novel	V170V	0.39
LUSC	chr1	151709343	Missense_Mutation	novel	R95W	0.12
LUSC	chr1	151705099	Missense_Mutation	NA	G447D	0.36	RRM_1
LUSC	chr1	151705837	Missense_Mutation	novel	Q419E	0.37	RRM_1
LUSC	chr1	151707798	Silent	novel	T208T	0.19
OV	chr1	151716057	5'UTR	novel		0.19
OV	chr1	151705067	Missense_Mutation	novel	P458S	0.17
OV	chr1	151707803	Missense_Mutation	novel	Y207N	0.38
OV	chr1	151714604	Missense_Mutation	NA	T73M	0.24
OV	chr1	151707806	Missense_Mutation	rs779194171	A206T	0.41
PAAD	chr1	151709281	Missense_Mutation	novel	F115L	0.08
PAAD	chr1	151707928	Missense_Mutation	novel	S165L	0.22
PRAD	chr1	151707546	Missense_Mutation	novel	A245T	0.4
READ	chr1	151709266	Silent	novel	T120T	0.1
SARC	chr1	151707153	Missense_Mutation	novel	P305R	0.14
SARC	chr1	151705876	Missense_Mutation	rs762261971	V406I	0.8	RRM_1
SARC	chr1	151707226	Missense_Mutation	NA	G281S	0.62
SARC	chr1	151715844	Intron	novel		0.24
SARC	chr1	151715845	Intron	rs372291437		0.2
SKCM	chr1	151707294	Missense_Mutation	novel	G258E	0.75
SKCM	chr1	151707294	Missense_Mutation	novel	G258E	0.83
SKCM	chr1	151705099	Missense_Mutation	NA	G447D	0.16	RRM_1
SKCM	chr1	151716093	5'UTR	novel		0.19
SKCM	chr1	151715926	Missense_Mutation	NA	R32L	0.27
SKCM	chr1	151709022	Silent	NA	T154T	0.07
SKCM	chr1	151715939	Missense_Mutation	rs778026308	E28K	0.23
SKCM	chr1	151705882	Missense_Mutation	NA	G404R	0.29	RRM_1
SKCM	chr1	151707524	Missense_Mutation	novel	P252L	0.3
SKCM	chr1	151709067	Silent	rs200147307	F139F	0.44
SKCM	chr1	151709789	Missense_Mutation	novel	M77I	0.46
STAD	chr1	151709749	Nonsense_Mutation	NA	R91*	0.39
STAD	chr1	151715893	Missense_Mutation	NA	Y43C	0.39
STAD	chr1	151709244	Missense_Mutation	rs770229986	R128W	0.2
STAD	chr1	151705907	Missense_Mutation	novel	E395D	0.44	RRM_1
STAD	chr1	151709263	Silent	rs375546699	I121I	0.16
STAD	chr1	151707793	Missense_Mutation	NA	A210D	0.17
STAD	chr1	151707632	Missense_Mutation	rs757437858	A216V	0.5
TGCT	chr1	151706702	Nonsense_Mutation	novel	Q319*	0.13
UCEC	chr1	151707854	Missense_Mutation	rs370209956	Q190K	0.49
UCEC	chr1	151715939	Missense_Mutation	rs778026308	E28K	0.34
UCEC	chr1	151709271	Missense_Mutation	novel	G119R	0.36
UCEC	chr1	151714623	Missense_Mutation	rs754604007	A67T	0.4
UCEC	chr1	151714661	Missense_Mutation	novel	T54I	0.23
UCEC	chr1	151709252	Missense_Mutation	NA	T125I	0.47
UCEC	chr1	151714466	Intron	novel		0.43
UCEC	chr1	151702803	3'UTR	novel		0.37
UCEC	chr1	151714432	Intron	novel		0.51
UCEC	chr1	151705040	3'UTR	novel		0.15
UCEC	chr1	151705089	Silent	NA	R450R	0.29
UCEC	chr1	151705893	Missense_Mutation	NA	F400C	0.47	RRM_1
UCEC	chr1	151709780	Silent	rs775554229	P80P	0.34
UCEC	chr1	151714453	Intron	novel		0.5
UCEC	chr1	151707620	Missense_Mutation	rs753294142	A220V	0.31
UCEC	chr1	151702716	3'UTR	novel		0.31
UCEC	chr1	151703397	3'UTR	novel		0.36
UCEC	chr1	151707620	Missense_Mutation	rs753294142	A220V	0.16
UCEC	chr1	151702826	3'UTR	novel		0.5
UCEC	chr1	151707531	Missense_Mutation	rs201319891	A250T	0.58
UCEC	chr1	151709780	Silent	rs775554229	P80P	0.49
UCEC	chr1	151715939	Missense_Mutation	rs778026308	E28K	0.12
UCEC	chr1	151705069	Missense_Mutation	novel	R457Q	0.4
UCEC	chr1	151707830	Missense_Mutation	rs747941563	A198T	0.51
UCEC	chr1	151707808	Missense_Mutation	novel	S205I	0.09
UCEC	chr1	151702832	3'UTR	novel		0.37
UCEC	chr1	151703294	3'UTR	novel		0.23
UCEC	chr1	151703294	3'UTR	novel		0.48
UCEC	chr1	151703335	3'UTR	novel		0.48
UCEC	chr1	151707631	Silent	rs749415167	A216A	0.24
UCEC	chr1	151709342	Missense_Mutation	rs766430217	R95Q	0.37
UCEC	chr1	151710637	Intron	novel		0.58
UCEC	chr1	151716805	5'UTR	novel		0.29
UCEC	chr1	151714451	Intron	novel		0.32
UCEC	chr1	151714649	Missense_Mutation	novel	R58Q	0.23
UCEC	chr1	151705120	Missense_Mutation	NA	A440V	0.16	RRM_1
UCEC	chr1	151705827	Missense_Mutation	NA	C422Y	0.2	RRM_1
UCEC	chr1	151707531	Missense_Mutation	rs201319891	A250T	0.16
UCEC	chr1	151709072	Missense_Mutation	NA	A138T	0.23
UCEC	chr1	151702777	3'UTR	novel		0.4
UCEC	chr1	151709048	Missense_Mutation	rs202171109	A146T	0.33
UCEC	chr1	151714456	Intron	novel		0.14
UCEC	chr1	151703188	3'UTR	novel		0.09
UCEC	chr1	151710677	Intron	novel		0.12
UCEC	chr1	151705090	Missense_Mutation	NA	R450H	0.27	RRM_1
UCEC	chr1	151715939	Missense_Mutation	rs778026308	E28K	0.3
UCEC	chr1	151702935	3'UTR	novel		0.38
UCEC	chr1	151706318	Silent	rs764410071	P344P	0.19
UCEC	chr1	151707226	Missense_Mutation	NA	G281S	0.44
UCEC	chr1	151710808	Intron	novel		0.38

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	AMP	0.1444	0.11282
CESC	AMP	0.4814	3.2002e-05
DLBC	DEL	0.0417	0.0017831
ESCA	AMP	0.4076	0.0022446
KIRC	AMP	0.0928	0.059566
LUSC	AMP	0.4331	1.6618e-06
PAAD	AMP	0.2174	0.085665
PCPG	AMP	0.1481	0.00029562
READ	AMP	0.2667	0.025154
SARC	AMP	0.3463	4.3422e-08
SKCM	AMP	0.4823	9.6912e-06
TGCT	AMP	0.3467	0.088103

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
MESO	0.0031	Kaplan-Meier Survival Analysis
KIRP	0.00022	Kaplan-Meier Survival Analysis
PAAD	0.0017	Kaplan-Meier Survival Analysis
PCPG	0.019	Kaplan-Meier Survival Analysis
BLCA	0.047	Kaplan-Meier Survival Analysis
LAML	0.05	Kaplan-Meier Survival Analysis
KICH	0.045	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
LUAD	0.034	Kaplan-Meier Survival Analysis
OV	0.019	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742