EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000159917 (Gene tree)
Gene ID: 9310
Gene Symbol: ZNF235
Alias: HZF6|ANF270|ZNF270|ZFP93
Full Name: zinc finger protein 235
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 76,979 bases
Position: chr19:44,228,729-44,305,707
Accession: 12866
RBP type: canonical RBP
Summary: This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein is a member of the Kruppel family of zinc finger proteins, and contains Kruppel-associated box (KRAB) A and B domains and 15 tandemly arrayed C2H2-type zinc fingers. It is an ortholog of the mouse Zfp93 protein. This gene is located in a cluster of zinc finger genes on 19q13.2. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	1	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	2	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	3	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	4	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	5	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	6	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	7	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	8	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	9	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	10	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	11	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	12	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	13	14
ENSP00000497018	zf-C2H2	PF00096.26	6.2e-80	14	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	1	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	2	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	3	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	4	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	5	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	6	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	7	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	8	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	9	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	10	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	11	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	12	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	13	14
ENSP00000291182	zf-C2H2	PF00096.26	6.9e-80	14	14
ENSP00000497018	zf-met	PF12874.7	1.2e-07	1	3
ENSP00000497018	zf-met	PF12874.7	1.2e-07	2	3
ENSP00000497018	zf-met	PF12874.7	1.2e-07	3	3
ENSP00000291182	zf-met	PF12874.7	1.3e-07	1	3
ENSP00000291182	zf-met	PF12874.7	1.3e-07	2	3
ENSP00000291182	zf-met	PF12874.7	1.3e-07	3	3

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000591609	ZNF235-205	946	-	ENSP00000465880	295 (aa)	-	K7EL19
ENST00000587921	ZNF235-202	4219	-	-	- (aa)	-	-
ENST00000589248	ZNF235-203	532	-	ENSP00000468609	87 (aa)	-	K7ES94
ENST00000589799	ZNF235-204	955	-	ENSP00000468695	83 (aa)	-	K7ESF8
ENST00000592844	ZNF235-206	616	-	ENSP00000465641	81 (aa)	-	K7EKI9
ENST00000291182	ZNF235-201	3188	-	ENSP00000291182	738 (aa)	-	Q14590
ENST00000650576	ZNF235-207	3162	XM_005259412	ENSP00000497018	734 (aa)	XP_005259469	UPI00002025C3

Gene Model

Click here to download ENSG00000159917's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05168	Herpes simplex virus 1 infection	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000159917	rs74796695	19	44301795	T	Low density lipoprotein cholesterol levels	29507422	unit increase	0.121	EFO_0004611
ENSG00000159917	rs74796695	19	44301795	T	Low density lipoprotein cholesterol levels	29507422	unit increase	0.121	EFO_0004611
ENSG00000159917	rs118092853	19	44285734	?	White blood cell count	30595370			EFO_0004308

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000159917's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000159917	ZNF235	99	88.626	ENSAMEG00000012930	ZNF235	99	75.068	Ailuropoda_melanoleuca
ENSG00000159917	ZNF235	100	95.799	ENSANAG00000037223	ZNF235	100	95.799	Aotus_nancymaae
ENSG00000159917	ZNF235	93	79.971	ENSBTAG00000007714	ZNF235	100	79.971	Bos_taurus
ENSG00000159917	ZNF235	100	95.913	ENSCJAG00000039837	ZNF235	100	95.913	Callithrix_jacchus
ENSG00000159917	ZNF235	100	88.011	ENSCAFG00000031857	ZNF235	100	88.011	Canis_familiaris
ENSG00000159917	ZNF235	97	88.202	ENSCAFG00020013058	ZNF235	100	88.202	Canis_lupus_dingo
ENSG00000159917	ZNF235	100	80.379	ENSCHIG00000014937	ZNF235	100	80.379	Capra_hircus
ENSG00000159917	ZNF235	100	92.141	ENSTSYG00000027063	ZNF235	100	92.141	Carlito_syrichta
ENSG00000159917	ZNF235	89	79.459	ENSCAPG00000002667	-	100	79.459	Cavia_aperea
ENSG00000159917	ZNF235	93	82.327	ENSCPOG00000039731	ZNF235	100	82.327	Cavia_porcellus
ENSG00000159917	ZNF235	100	94.959	ENSCCAG00000037645	ZNF235	100	94.959	Cebus_capucinus
ENSG00000159917	ZNF235	100	96.748	ENSCATG00000029278	ZNF235	100	96.748	Cercocebus_atys
ENSG00000159917	ZNF235	94	95.665	ENSCSAG00000003323	ZNF235	100	95.665	Chlorocebus_sabaeus
ENSG00000159917	ZNF235	100	97.275	ENSCANG00000029539	ZNF235	100	97.275	Colobus_angolensis_palliatus
ENSG00000159917	ZNF235	89	71.865	ENSCGRG00001015424	-	100	71.865	Cricetulus_griseus_chok1gshd
ENSG00000159917	ZNF235	91	87.275	ENSDNOG00000042106	ZNF235	99	87.275	Dasypus_novemcinctus
ENSG00000159917	ZNF235	93	87.059	ENSEASG00005013637	ZNF235	100	87.059	Equus_asinus_asinus
ENSG00000159917	ZNF235	93	85.591	ENSECAG00000023724	ZNF235	100	85.591	Equus_caballus
ENSG00000159917	ZNF235	90	75.114	ENSEEUG00000006864	ZNF235	89	75.114	Erinaceus_europaeus
ENSG00000159917	ZNF235	100	87.127	ENSFCAG00000043995	ZNF235	100	87.127	Felis_catus
ENSG00000159917	ZNF235	99	85.910	ENSFDAG00000015590	ZNF235	99	85.910	Fukomys_damarensis
ENSG00000159917	ZNF235	100	99.322	ENSGGOG00000008607	ZNF235	100	99.322	Gorilla_gorilla
ENSG00000159917	ZNF235	96	86.040	ENSHGLG00000003657	ZNF235	97	86.040	Heterocephalus_glaber_female
ENSG00000159917	ZNF235	99	78.358	ENSHGLG00100010077	ZNF235	100	83.121	Heterocephalus_glaber_male
ENSG00000159917	ZNF235	89	56.336	ENSJJAG00000024260	-	99	62.137	Jaculus_jaculus
ENSG00000159917	ZNF235	89	88.532	ENSLAFG00000011186	ZNF235	99	88.532	Loxodonta_africana
ENSG00000159917	ZNF235	100	97.019	ENSMFAG00000035923	ZNF235	100	97.019	Macaca_fascicularis
ENSG00000159917	ZNF235	100	97.019	ENSMMUG00000012801	ZNF235	100	97.019	Macaca_mulatta
ENSG00000159917	ZNF235	100	96.748	ENSMNEG00000028194	ZNF235	100	96.748	Macaca_nemestrina
ENSG00000159917	ZNF235	100	96.594	ENSMLEG00000034346	ZNF235	100	96.594	Mandrillus_leucophaeus
ENSG00000159917	ZNF235	100	93.089	ENSMICG00000004971	ZNF235	100	93.089	Microcebus_murinus
ENSG00000159917	ZNF235	100	72.727	ENSMOCG00000017799	-	100	72.727	Microtus_ochrogaster
ENSG00000159917	ZNF235	100	85.578	ENSMPUG00000006476	ZNF235	100	85.578	Mustela_putorius_furo
ENSG00000159917	ZNF235	99	84.131	ENSMLUG00000013784	ZNF235	100	84.131	Myotis_lucifugus
ENSG00000159917	ZNF235	91	81.109	ENSNGAG00000010473	-	100	81.109	Nannospalax_galili
ENSG00000159917	ZNF235	89	83.614	ENSODEG00000008851	-	100	83.614	Octodon_degus
ENSG00000159917	ZNF235	95	75.683	ENSOCUG00000017842	ZNF235	99	75.683	Oryctolagus_cuniculus
ENSG00000159917	ZNF235	100	99.591	ENSPPAG00000031448	ZNF235	100	99.591	Pan_paniscus
ENSG00000159917	ZNF235	100	86.141	ENSPPRG00000014617	ZNF235	100	86.141	Panthera_pardus
ENSG00000159917	ZNF235	100	86.277	ENSPTIG00000021573	ZNF235	100	86.277	Panthera_tigris_altaica
ENSG00000159917	ZNF235	100	99.458	ENSPTRG00000011112	ZNF235	100	99.458	Pan_troglodytes
ENSG00000159917	ZNF235	98	98.734	ENSPANG00000006495	ZNF235	100	96.477	Papio_anubis
ENSG00000159917	ZNF235	100	98.509	ENSPPYG00000010086	ZNF235	100	98.509	Pongo_abelii
ENSG00000159917	ZNF235	93	83.048	ENSPCAG00000005203	ZNF235	92	83.048	Procavia_capensis
ENSG00000159917	ZNF235	100	91.599	ENSPCOG00000022996	ZNF235	100	91.599	Propithecus_coquereli
ENSG00000159917	ZNF235	100	81.892	ENSPVAG00000004392	ZNF235	100	81.892	Pteropus_vampyrus
ENSG00000159917	ZNF235	100	96.049	ENSRBIG00000026071	ZNF235	100	96.049	Rhinopithecus_bieti
ENSG00000159917	ZNF235	100	95.935	ENSRROG00000033359	ZNF235	100	95.935	Rhinopithecus_roxellana
ENSG00000159917	ZNF235	100	96.070	ENSSBOG00000028285	ZNF235	100	96.070	Saimiri_boliviensis_boliviensis
ENSG00000159917	ZNF235	72	80.228	ENSSARG00000008140	ZNF235	92	80.228	Sorex_araneus
ENSG00000159917	ZNF235	95	81.818	ENSSSCG00000022434	ZNF235	100	73.919	Sus_scrofa
ENSG00000159917	ZNF235	100	85.908	ENSTBEG00000001345	ZNF235	100	85.908	Tupaia_belangeri
ENSG00000159917	ZNF235	98	89.873	ENSTTRG00000006707	ZNF235	100	85.386	Tursiops_truncatus
ENSG00000159917	ZNF235	90	86.646	ENSUAMG00000005458	ZNF235	93	86.667	Ursus_americanus
ENSG00000159917	ZNF235	100	85.559	ENSUMAG00000023068	ZNF235	100	85.559	Ursus_maritimus
ENSG00000159917	ZNF235	91	85.135	ENSVPAG00000000139	ZNF235	76	90.229	Vicugna_pacos
ENSG00000159917	ZNF235	95	87.320	ENSVVUG00000008581	ZNF235	99	87.320	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003700	DNA-binding transcription factor activity	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function