EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000160214 (Gene tree)
Gene ID: 8568
Gene Symbol: RRP1
Alias: NNP-1|Nop52|NOP52|RRP1A|D21S2056E
Full Name: ribosomal RNA processing 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 15,781 bases
Position: chr21:43,789,513-43,805,293
Accession: 18785
RBP type: canonical RBP
Summary: The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000417464	Nop52	PF05997.12	9.7e-70	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000473988	RRP1-203	627	-	-	- (aa)	-	-
ENST00000471909	RRP1-202	2544	-	-	- (aa)	-	-
ENST00000467112	RRP1-201	3019	-	-	- (aa)	-	-
ENST00000475534	RRP1-204	588	-	-	- (aa)	-	-
ENST00000492638	RRP1-206	1017	-	-	- (aa)	-	-
ENST00000497547	RRP1-207	3022	XM_017028485	ENSP00000417464	461 (aa)	XP_016883974	P56182
ENST00000483896	RRP1-205	805	-	ENSP00000426898	45 (aa)	-	D6RE82

Gene Model

Click here to download ENSG00000160214's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000160214	Platelet Function Tests	1.8437000E-005	-
ENSG00000160214	Platelet Function Tests	2.7292800E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000160214's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000160214	RRP1	78	65.714	ENSG00000160208	RRP1B	55	50.000

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000160214	RRP1	98	90.909	ENSAMEG00000011448	RRP1	89	74.020	Ailuropoda_melanoleuca
ENSG00000160214	RRP1	61	49.117	ENSACIG00000019121	rrp1	57	49.117	Amphilophus_citrinellus
ENSG00000160214	RRP1	82	64.865	ENSAOCG00000017894	-	75	50.430	Amphiprion_ocellaris
ENSG00000160214	RRP1	100	100.000	ENSANAG00000037815	RRP1	100	85.683	Aotus_nancymaae
ENSG00000160214	RRP1	76	58.824	ENSACLG00000010281	-	77	55.330	Astatotilapia_calliptera
ENSG00000160214	RRP1	96	93.023	ENSBTAG00000003981	RRP1	99	64.240	Bos_taurus
ENSG00000160214	RRP1	100	100.000	ENSCJAG00000043205	RRP1	87	90.802	Callithrix_jacchus
ENSG00000160214	RRP1	98	86.364	ENSCAFG00000010646	RRP1	92	71.496	Canis_familiaris
ENSG00000160214	RRP1	72	53.687	ENSCAFG00000010621	RRP1B	53	50.398	Canis_familiaris
ENSG00000160214	RRP1	78	62.857	ENSCAFG00020018901	RRP1B	58	50.943	Canis_lupus_dingo
ENSG00000160214	RRP1	98	86.364	ENSCAFG00020018979	RRP1	92	71.496	Canis_lupus_dingo
ENSG00000160214	RRP1	96	95.349	ENSCHIG00000020948	RRP1	99	65.385	Capra_hircus
ENSG00000160214	RRP1	98	97.727	ENSTSYG00000012831	RRP1	99	72.281	Carlito_syrichta
ENSG00000160214	RRP1	66	70.606	ENSCAPG00000008576	RRP1	83	70.695	Cavia_aperea
ENSG00000160214	RRP1	96	90.698	ENSCPOG00000038986	RRP1	98	65.652	Cavia_porcellus
ENSG00000160214	RRP1	100	100.000	ENSCCAG00000029828	RRP1	100	90.497	Cebus_capucinus
ENSG00000160214	RRP1	78	65.714	ENSCCAG00000029384	RRP1B	50	56.418	Cebus_capucinus
ENSG00000160214	RRP1	100	94.577	ENSCATG00000015632	RRP1	100	94.577	Cercocebus_atys
ENSG00000160214	RRP1	96	90.698	ENSCLAG00000011639	RRP1	98	68.376	Chinchilla_lanigera
ENSG00000160214	RRP1	98	97.727	ENSCSAG00000007936	RRP1	100	95.758	Chlorocebus_sabaeus
ENSG00000160214	RRP1	78	65.714	ENSCHOG00000002426	-	54	45.897	Choloepus_hoffmanni
ENSG00000160214	RRP1	69	54.839	ENSCING00000003304	-	73	32.362	Ciona_intestinalis
ENSG00000160214	RRP1	91	79.236	ENSCANG00000042611	RRP1	85	79.236	Colobus_angolensis_palliatus
ENSG00000160214	RRP1	78	65.714	ENSCANG00000040952	RRP1B	54	50.365	Colobus_angolensis_palliatus
ENSG00000160214	RRP1	98	88.636	ENSCGRG00001011920	Rrp1	92	74.257	Cricetulus_griseus_chok1gshd
ENSG00000160214	RRP1	71	68.750	ENSCGRG00001023882	-	55	69.841	Cricetulus_griseus_chok1gshd
ENSG00000160214	RRP1	98	88.636	ENSCGRG00000008915	Rrp1	92	74.257	Cricetulus_griseus_crigri
ENSG00000160214	RRP1	80	66.667	ENSCSEG00000020711	-	64	51.445	Cynoglossus_semilaevis
ENSG00000160214	RRP1	93	54.762	ENSCVAG00000017568	-	88	45.455	Cyprinodon_variegatus
ENSG00000160214	RRP1	98	97.727	ENSDNOG00000019880	RRP1	99	70.878	Dasypus_novemcinctus
ENSG00000160214	RRP1	90	63.679	ENSDORG00000002104	Rrp1	99	64.019	Dipodomys_ordii
ENSG00000160214	RRP1	98	90.909	ENSETEG00000002963	-	99	51.724	Echinops_telfairi
ENSG00000160214	RRP1	78	62.857	ENSEASG00005001687	RRP1B	56	48.931	Equus_asinus_asinus
ENSG00000160214	RRP1	98	93.182	ENSEASG00005001673	RRP1	100	70.282	Equus_asinus_asinus
ENSG00000160214	RRP1	98	93.182	ENSECAG00000015703	RRP1	100	70.716	Equus_caballus
ENSG00000160214	RRP1	78	62.857	ENSECAG00000018018	RRP1B	56	48.694	Equus_caballus
ENSG00000160214	RRP1	73	60.606	ENSELUG00000015885	-	87	49.379	Esox_lucius
ENSG00000160214	RRP1	98	88.636	ENSFCAG00000008434	RRP1	91	73.976	Felis_catus
ENSG00000160214	RRP1	96	90.698	ENSFDAG00000013728	RRP1	99	65.591	Fukomys_damarensis
ENSG00000160214	RRP1	80	63.889	ENSGAFG00000020561	-	59	73.438	Gambusia_affinis
ENSG00000160214	RRP1	78	62.857	ENSGACG00000001438	rrp1	52	48.521	Gasterosteus_aculeatus
ENSG00000160214	RRP1	78	65.714	ENSGGOG00000012069	RRP1B	55	50.000	Gorilla_gorilla
ENSG00000160214	RRP1	100	98.482	ENSGGOG00000000173	RRP1	100	98.482	Gorilla_gorilla
ENSG00000160214	RRP1	78	65.714	ENSHGLG00000004968	RRP1B	61	46.207	Heterocephalus_glaber_female
ENSG00000160214	RRP1	96	93.023	ENSHGLG00000017085	RRP1	95	64.859	Heterocephalus_glaber_female
ENSG00000160214	RRP1	76	55.882	ENSIPUG00000000673	-	67	45.143	Ictalurus_punctatus
ENSG00000160214	RRP1	96	95.349	ENSSTOG00000011116	RRP1	96	73.882	Ictidomys_tridecemlineatus
ENSG00000160214	RRP1	98	93.182	ENSJJAG00000018886	Rrp1	99	69.892	Jaculus_jaculus
ENSG00000160214	RRP1	80	58.333	ENSKMAG00000005539	rrp1	51	48.696	Kryptolebias_marmoratus
ENSG00000160214	RRP1	80	61.111	ENSLBEG00000021417	RRP1	89	47.059	Labrus_bergylta
ENSG00000160214	RRP1	98	95.455	ENSLAFG00000022901	RRP1	91	69.042	Loxodonta_africana
ENSG00000160214	RRP1	78	71.429	ENSLAFG00000000766	RRP1B	80	57.726	Loxodonta_africana
ENSG00000160214	RRP1	98	97.727	ENSMFAG00000003202	RRP1	100	93.275	Macaca_fascicularis
ENSG00000160214	RRP1	98	97.727	ENSMMUG00000012304	RRP1	100	92.842	Macaca_mulatta
ENSG00000160214	RRP1	98	97.727	ENSMNEG00000031210	RRP1	100	93.059	Macaca_nemestrina
ENSG00000160214	RRP1	92	94.550	ENSMLEG00000037797	RRP1	99	94.550	Mandrillus_leucophaeus
ENSG00000160214	RRP1	98	88.636	ENSMAUG00000017653	Rrp1	98	57.051	Mesocricetus_auratus
ENSG00000160214	RRP1	98	97.727	ENSMICG00000004700	RRP1	99	74.732	Microcebus_murinus
ENSG00000160214	RRP1	78	65.714	ENSMICG00000004686	RRP1B	56	50.119	Microcebus_murinus
ENSG00000160214	RRP1	96	76.744	ENSMOCG00000015687	Rrp1	99	55.534	Microtus_ochrogaster
ENSG00000160214	RRP1	80	58.333	ENSMMOG00000019175	rrp1	86	46.356	Mola_mola
ENSG00000160214	RRP1	98	65.909	ENSMODG00000021036	-	52	62.953	Monodelphis_domestica
ENSG00000160214	RRP1	76	58.824	ENSMALG00000010310	rrp1	88	49.711	Monopterus_albus
ENSG00000160214	RRP1	71	65.625	MGP_CAROLIEiJ_G0021376	Rrp1b	53	66.667	Mus_caroli
ENSG00000160214	RRP1	96	86.047	MGP_CAROLIEiJ_G0015508	Rrp1	96	63.136	Mus_caroli
ENSG00000160214	RRP1	96	86.047	ENSMUSG00000061032	Rrp1	96	62.076	Mus_musculus
ENSG00000160214	RRP1	71	68.750	ENSMUSG00000058392	Rrp1b	53	68.254	Mus_musculus
ENSG00000160214	RRP1	71	65.625	MGP_PahariEiJ_G0023695	Rrp1b	53	66.667	Mus_pahari
ENSG00000160214	RRP1	96	86.047	MGP_PahariEiJ_G0030921	Rrp1	99	59.309	Mus_pahari
ENSG00000160214	RRP1	71	68.750	MGP_SPRETEiJ_G0022290	Rrp1b	53	68.254	Mus_spretus
ENSG00000160214	RRP1	96	86.047	MGP_SPRETEiJ_G0016321	Rrp1	98	60.870	Mus_spretus
ENSG00000160214	RRP1	98	95.455	ENSMPUG00000009826	RRP1	96	65.032	Mustela_putorius_furo
ENSG00000160214	RRP1	98	95.455	ENSMLUG00000017788	RRP1	99	64.023	Myotis_lucifugus
ENSG00000160214	RRP1	98	86.364	ENSNGAG00000022344	Rrp1	93	56.416	Nannospalax_galili
ENSG00000160214	RRP1	100	96.095	ENSNLEG00000034734	RRP1	100	96.095	Nomascus_leucogenys
ENSG00000160214	RRP1	98	88.636	ENSOPRG00000001319	RRP1	97	69.577	Ochotona_princeps
ENSG00000160214	RRP1	69	80.645	ENSOANG00000006472	-	99	56.000	Ornithorhynchus_anatinus
ENSG00000160214	RRP1	73	80.795	ENSOCUG00000022843	-	76	80.795	Oryctolagus_cuniculus
ENSG00000160214	RRP1	98	90.909	ENSOGAG00000006105	RRP1	99	75.000	Otolemur_garnettii
ENSG00000160214	RRP1	78	68.571	ENSOGAG00000009872	RRP1B	62	50.122	Otolemur_garnettii
ENSG00000160214	RRP1	96	95.349	ENSOARG00000011434	RRP1	99	61.954	Ovis_aries
ENSG00000160214	RRP1	100	99.566	ENSPPAG00000029050	RRP1	100	99.566	Pan_paniscus
ENSG00000160214	RRP1	98	88.636	ENSPPRG00000010656	RRP1	90	73.735	Panthera_pardus
ENSG00000160214	RRP1	84	61.750	ENSPTIG00000019473	RRP1	86	62.895	Panthera_tigris_altaica
ENSG00000160214	RRP1	100	99.566	ENSPTRG00000013962	RRP1	100	99.566	Pan_troglodytes
ENSG00000160214	RRP1	78	65.714	ENSPTRG00000013958	RRP1B	55	50.000	Pan_troglodytes
ENSG00000160214	RRP1	98	97.727	ENSPANG00000015097	RRP1	100	93.709	Papio_anubis
ENSG00000160214	RRP1	82	67.568	ENSPSIG00000008152	RRP1B	52	54.524	Pelodiscus_sinensis
ENSG00000160214	RRP1	71	53.125	ENSPMGG00000007512	-	84	39.944	Periophthalmus_magnuspinnatus
ENSG00000160214	RRP1	98	88.636	ENSPEMG00000018421	Rrp1	91	76.250	Peromyscus_maniculatus_bairdii
ENSG00000160214	RRP1	78	65.714	ENSPCIG00000015513	RRP1B	57	51.951	Phascolarctos_cinereus
ENSG00000160214	RRP1	98	68.182	ENSPCIG00000015523	-	75	65.205	Phascolarctos_cinereus
ENSG00000160214	RRP1	98	100.000	ENSPPYG00000011474	RRP1	100	97.397	Pongo_abelii
ENSG00000160214	RRP1	98	93.182	ENSPCAG00000008370	-	95	58.028	Procavia_capensis
ENSG00000160214	RRP1	98	100.000	ENSPCOG00000017706	RRP1	99	71.030	Propithecus_coquereli
ENSG00000160214	RRP1	78	68.571	ENSPCOG00000017927	RRP1B	57	50.597	Propithecus_coquereli
ENSG00000160214	RRP1	98	97.727	ENSPVAG00000009925	-	61	65.248	Pteropus_vampyrus
ENSG00000160214	RRP1	96	86.047	ENSRNOG00000001203	Rrp1	98	65.812	Rattus_norvegicus
ENSG00000160214	RRP1	98	97.727	ENSRBIG00000032082	RRP1	100	94.577	Rhinopithecus_bieti
ENSG00000160214	RRP1	98	97.727	ENSRROG00000039799	RRP1	100	94.794	Rhinopithecus_roxellana
ENSG00000160214	RRP1	100	100.000	ENSSBOG00000034689	RRP1	100	83.983	Saimiri_boliviensis_boliviensis
ENSG00000160214	RRP1	69	61.059	ENSSHAG00000010304	-	92	63.816	Sarcophilus_harrisii
ENSG00000160214	RRP1	67	45.619	ENSSFOG00015003932	-	51	45.619	Scleropages_formosus
ENSG00000160214	RRP1	78	57.143	ENSSMAG00000016847	-	80	49.848	Scophthalmus_maximus
ENSG00000160214	RRP1	96	95.349	ENSSSCG00000037061	RRP1	99	68.026	Sus_scrofa
ENSG00000160214	RRP1	78	65.714	ENSSSCG00000021698	RRP1B	52	56.069	Sus_scrofa
ENSG00000160214	RRP1	82	62.162	ENSTRUG00000017592	rrp1	97	50.720	Takifugu_rubripes
ENSG00000160214	RRP1	82	62.162	ENSTNIG00000005053	rrp1	54	50.000	Tetraodon_nigroviridis
ENSG00000160214	RRP1	77	50.820	ENSTBEG00000000422	RRP1B	62	50.820	Tupaia_belangeri
ENSG00000160214	RRP1	98	84.091	ENSTBEG00000001260	-	62	76.087	Tupaia_belangeri
ENSG00000160214	RRP1	78	65.714	ENSTTRG00000000723	RRP1B	57	49.279	Tursiops_truncatus
ENSG00000160214	RRP1	96	95.349	ENSTTRG00000011162	RRP1	84	76.471	Tursiops_truncatus
ENSG00000160214	RRP1	73	61.404	ENSUAMG00000014189	-	97	58.571	Ursus_americanus
ENSG00000160214	RRP1	72	51.032	ENSUMAG00000025510	RRP1B	57	55.068	Ursus_maritimus
ENSG00000160214	RRP1	90	66.271	ENSUMAG00000025507	RRP1	98	62.990	Ursus_maritimus
ENSG00000160214	RRP1	72	53.529	ENSVVUG00000024509	RRP1B	53	50.265	Vulpes_vulpes
ENSG00000160214	RRP1	69	57.317	ENSVVUG00000024498	-	66	59.925	Vulpes_vulpes
ENSG00000160214	RRP1	80	63.889	ENSXCOG00000008312	-	66	54.802	Xiphophorus_couchianus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	20926688.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005730	nucleolus	16780588.	HDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006364	rRNA processing	21873635.	IBA	Process
GO:0030687	preribosome, large subunit precursor	21873635.	IBA	Component
GO:0030688	preribosome, small subunit precursor	-	IEA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr21	43802291	Missense_Mutation	NA	E343Q	0.45
BLCA	chr21	43792722	Silent	rs762124046	T89T	0.31
BLCA	chr21	43792701	Silent	novel	L82L	0.44
BLCA	chr21	43802324	Missense_Mutation	novel	E354Q	0.17
BLCA	chr21	43797398	Intron	novel		0.18
BLCA	chr21	43799617	Missense_Mutation	novel	D287N	0.25
BRCA	chr21	43802338	Silent	NA	Q358Q	0.15
BRCA	chr21	43800610	Missense_Mutation	rs376330937	R329W	0.25
BRCA	chr21	43793397	Missense_Mutation	novel	F118C	0.53	Nop52
BRCA	chr21	43792727	Missense_Mutation	NA	A91V	0.14	Nop52
BRCA	chr21	43789543	5'UTR	novel		0.43
BRCA	chr21	43797966	Missense_Mutation	NA	P226L	0.38
BRCA	chr21	43802355	Missense_Mutation	novel	Q364P	0.06
CESC	chr21	43793126	Intron	novel		0.33
CESC	chr21	43795210	Missense_Mutation	rs367993051	E128K	0.37	Nop52
CESC	chr21	43803693	Missense_Mutation	novel	R435S	0.22
CESC	chr21	43797679	Missense_Mutation	novel	A201S	0.17	Nop52
COAD	chr21	43800599	Missense_Mutation	novel	Y325C	0.1
COAD	chr21	43793290	Intron	novel		0.86
COAD	chr21	43797967	Silent	rs771504012	P226P	0.29
COAD	chr21	43793239	Intron	novel		0.27
COAD	chr21	43793210	Intron	novel		0.39
COAD	chr21	43793366	Missense_Mutation	novel	T108A	0.47	Nop52
COAD	chr21	43798020	Missense_Mutation	novel	A244V	0.17
COAD	chr21	43793210	Intron	novel		0.37
COAD	chr21	43803842	3'UTR	rs534202684		0.23
GBM	chr21	43791372	Silent	novel	L52L	0.19
HNSC	chr21	43799577	Silent	novel	I273I	0.12
HNSC	chr21	43797985	Silent	novel	L232L	0.36
HNSC	chr21	43793365	Missense_Mutation	novel	W107C	0.07	Nop52
HNSC	chr21	43793357	Missense_Mutation	rs748434339	R105C	0.2	Nop52
KICH	chr21	43792942	Intron	novel		0.18
KIRC	chr21	43798041	Frame_Shift_Ins	novel	E252*	0.08
LIHC	chr21	43797380	Intron	novel		0.32
LIHC	chr21	43793187	Intron	novel		0.88
LUAD	chr21	43797509	Silent	NA	I170I	0.43
LUAD	chr21	43793343	Missense_Mutation	NA	W100L	0.84	Nop52
LUAD	chr21	43800546	Silent	NA	L307L	0.12
LUAD	chr21	43797429	Missense_Mutation	rs750460535	E144K	0.29	Nop52
LUAD	chr21	43797549	Missense_Mutation	novel	E184K	0.25	Nop52
LUAD	chr21	43800564	Silent	rs199611237	R313R	0.14
LUSC	chr21	43792682	Missense_Mutation	novel	G76E	0.16	Nop52
MESO	chr21	43803679	Missense_Mutation	rs766713616	R431C	0.89
OV	chr21	43798088	Missense_Mutation	novel	K267Q	0.29
OV	chr21	43797361	Intron	novel		0.14
OV	chr21	43797527	Silent	novel	E176E	0.07
OV	chr21	43798036	Silent	novel	E249E	0.79
SARC	chr21	43803662	Missense_Mutation	rs375793237	R425H	0.58
SKCM	chr21	43793329	Silent	novel	F95F	0.25
SKCM	chr21	43793350	Silent	novel	T102T	0.22
SKCM	chr21	43791426	Silent	NA	L70L	0.93
SKCM	chr21	43792722	Silent	rs762124046	T89T	0.28
SKCM	chr21	43792723	Missense_Mutation	rs767836326	E90K	0.28	Nop52
SKCM	chr21	43793338	Silent	NA	A98A	0.29
SKCM	chr21	43793283	Intron	novel		0.55
SKCM	chr21	43797503	Silent	NA	H168H	0.33
STAD	chr21	43797367	Intron	novel		0.46
STAD	chr21	43798063	Silent	rs765236197	D258D	0.2
STAD	chr21	43797661	Missense_Mutation	rs371737632	D195N	0.36	Nop52
STAD	chr21	43795195	Silent	novel	R123R	0.07
THCA	chr21	43803512	Missense_Mutation	novel	G375A	0.25
THCA	chr21	43802271	Splice_Region	novel		0.54
UCEC	chr21	43803782	3'UTR	novel		0.08
UCEC	chr21	43793366	Missense_Mutation	novel	T108A	0.36	Nop52
UCEC	chr21	43795215	Silent	novel	S129S	0.43
UCEC	chr21	43803662	Missense_Mutation	rs375793237	R425H	0.27
UCEC	chr21	43799620	Missense_Mutation	rs766636330	D288N	0.18
UCEC	chr21	43803867	3'UTR	novel		0.25
UCEC	chr21	43797932	Nonsense_Mutation	rs780122512	R215*	0.36	Nop52
UCEC	chr21	43797446	Silent	novel	L149L	0.3
UCEC	chr21	43802316	Missense_Mutation	rs559589580	R351H	0.43
UCEC	chr21	43803822	3'UTR	rs750051414		0.56
UCEC	chr21	43791367	Missense_Mutation	novel	E51K	0.39	Nop52
UCEC	chr21	43797679	Missense_Mutation	rs753419754	A201T	0.3	Nop52
UCEC	chr21	43798096	Silent	rs774930391	P269P	0.48
UCEC	chr21	43798087	Missense_Mutation	novel	E266D	0.28
UCEC	chr21	43800614	Missense_Mutation	novel	K330T	0.43
UCEC	chr21	43792675	Nonsense_Mutation	rs747889574	E74*	0.28	Nop52
UCEC	chr21	43800592	Missense_Mutation	rs200706235	R323C	0.17
UCEC	chr21	43797541	Missense_Mutation	novel	G181D	0.2	Nop52
UCEC	chr21	43793358	Missense_Mutation	rs768764518	R105H	0.36	Nop52
UCEC	chr21	43797428	Silent	rs187585477	I143I	0.16
UCEC	chr21	43791378	Missense_Mutation	rs754160691	K54N	0.24	Nop52
UCS	chr21	43797546	Missense_Mutation	rs758930459	E183K	0.51	Nop52

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
OV	DEL	0.3489	0.022578
THYM	AMP	0.0163	0.24554

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.02	Kaplan-Meier Survival Analysis
ACC	0.0051	Kaplan-Meier Survival Analysis
SKCM	0.00013	Kaplan-Meier Survival Analysis
UCEC	0.019	Kaplan-Meier Survival Analysis
LIHC	0.00082	Kaplan-Meier Survival Analysis
UVM	0.0028	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742