12773480 | The dsRNA binding protein family: critical roles, diverse cellular functions. | FASEB J | 2003 Jun | Saunders LR | - |
25172485 | Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. | J Immunol | 2014 Oct 1 | Yang S | doi: 10.4049/jimmunol.1401136 |
9738463 | The double-stranded RNA-binding domains of Xenopus laevis ADAR1 exhibit different RNA-binding behaviors. | FEBS Lett | 1998 Aug 28 | Brooks R | - |
11070079 | Chimeric double-stranded RNA-specific adenosine deaminase ADAR1 proteins reveal functional selectivity of double-stranded RNA-binding domains from ADAR1 and protein kinase PKR. | Proc Natl Acad Sci U S A | 2000 Nov 7 | Liu Y | - |
17000903 | RNA aptamers binding the double-stranded RNA-binding domain. | RNA | 2006 Nov | Hallegger M | - |
21490091 | Enhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinase. | J Virol | 2011 Sep | Gelinas JF | doi: 10.1128/JVI.00240-11 |
20863128 | Minor-groove-modulating adenosine replacements control protein binding and RNAi activity in siRNAs. | ACS Chem Biol | 2010 Dec 17 | Peacock H | doi: 10.1021/cb100245u |
24753571 | A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1. | Proc Natl Acad Sci U S A | 2014 May 6 | Barraud P | doi: 10.1073/pnas.1323698111 |
11689059 | Vaccinia virus E3L interferon resistance protein inhibits the interferon-induced adenosine deaminase A-to-I editing activity. | Virology | 2001 Oct 25 | Liu Y | - |
9988754 | Editing of glutamate receptor subunit B pre-mRNA by splice-site variants of interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1. | J Biol Chem | 1999 Feb 19 | Liu Y | - |
8627722 | Mechanism of interferon action: functionally distinct RNA-binding and catalytic domains in the interferon-inducible, double-stranded RNA-specific adenosine deaminase. | J Virol | 1996 Mar | Liu Y | - |
7972084 | Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. | Proc Natl Acad Sci U S A | 1994 Nov 22 | Kim U | - |
12719472 | Distinct in vivo roles for double-stranded RNA-binding domains of the Xenopus RNA-editing enzyme ADAR1 in chromosomal targeting. | J Cell Biol | 2003 Apr 28 | Doyle M | - |
12429827 | Nucleocytoplasmic distribution of human RNA-editing enzyme ADAR1 is modulated by double-stranded RNA-binding domains, a leucine-rich export signal, and a putative dimerization domain. | Mol Biol Cell | 2002 Nov | Strehblow A | - |
15843431 | Chromosomal storage of the RNA-editing enzyme ADAR1 in Xenopus oocytes. | Mol Biol Cell | 2005 Jul | Sallacz NB | - |
19124606 | RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1. | Mol Cell Biol | 2009 Mar | Fritz J | doi: 10.1128/MCB.01519-08 |
25064266 | HIV-1 translation and its regulation by cellular factors PKR and PACT. | Virus Res | 2014 Nov 26 | Burugu S | doi: 10.1016/j.virusres.2014.07.014 |
25926645 | New Noncoding Lytic Transcripts Derived from the Epstein-Barr Virus Latency Origin of Replication, oriP, Are Hyperedited, Bind the Paraspeckle Protein, NONO/p54nrb, and Support Viral Lytic Transcription. | J Virol | 2015 Jul | Cao S | doi: 10.1128/JVI.00608-15 |
27040499 | TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins. | Cell | 2016 Apr 21 | McMahon AC | doi: 10.1016/j.cell.2016.03.007 |
23728176 | MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth. | J Clin Invest | 2013 Jun | Nemlich Y | - |
28984845 | Site-directed RNA editing by adenosine deaminase acting on RNA for correction of the genetic code in gene therapy. | Gene Ther | 2017 Dec | Azad MTA | doi: 10.1038/gt.2017.90 |
30426900 | Comparative Activity of Adenosine Deaminase Acting on RNA (ADARs) Isoforms for Correction of Genetic Code in Gene Therapy. | Curr Gene Ther | 2019 | Azad MTA | doi: 10.2174/1566523218666181114122116. |
10373439 | Serotonin-2C receptor pre-mRNA editing in rat brain and in vitro by splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1. | J Biol Chem | 1999 Jun 25 | Liu Y | - |
12954622 | Intracellular localization of differentially regulated RNA-specific adenosine deaminase isoforms in inflammation. | J Biol Chem | 2003 Nov 14 | Yang JH | - |
9735305 | Double-stranded RNA-specific adenosine deaminase: nucleic acid binding properties. | Methods | 1998 Jul | Liu Y | - |
9636358 | Adenovirus VAI RNA antagonizes the RNA-editing activity of the ADAR adenosine deaminase. | Virology | 1998 Jun 5 | Lei M | - |
10376681 | Editing of messenger RNA precursors and of tRNAs by adenosine to inosine conversion. | FEBS Lett | 1999 Jun 4 | Keller W | - |
12453429 | Induction of protein translation by ADAR1 within living cell nuclei is not dependent on RNA editing. | Mol Cell | 2002 Nov | Herbert A | - |
11451992 | The human but not the Xenopus RNA-editing enzyme ADAR1 has an atypical nuclear localization signal and displays the characteristics of a shuttling protein. | Mol Biol Cell | 2001 Jul | Eckmann CR | - |
11421361 | Substrate recognition by ADAR1 and ADAR2. | RNA | 2001 Jun | Wong SK | - |
16177183 | Modulation of ADAR1 editing activity by Z-RNA in vitro. | Nucleic Acids Res | 2005 Sep 21 | Koeris M | - |
15556947 | ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells. | J Biol Chem | 2005 Feb 4 | Yang W | - |
19713932 | Editing independent effects of ADARs on the miRNA/siRNA pathways. | EMBO J | 2009 Oct 21 | Heale BS | doi: 10.1038/emboj.2009.244 |
19605474 | ADAR1 interacts with PKR during human immunodeficiency virus infection of lymphocytes and contributes to viral replication. | J Virol | 2009 Oct | Clerzius G | doi: 10.1128/JVI.02457-08 |
25708366 | ADAR1 is required for differentiation and neural induction by regulating microRNA processing in a catalytically independent manner. | Cell Res | 2015 Apr | Chen T | doi: 10.1038/cr.2015.24 |
24393560 | Mammalian conserved ADAR targets comprise only a small fragment of the human editosome. | Genome Biol | 2014 Jan 7 | Pinto Y | doi: 10.1186/gb-2014-15-1-r5. |
24020926 | The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication. | Retrovirology | 2013 Sep 11 | Clerzius G | doi: 10.1186/1742-4690-10-96. |
27256387 | Controlling the Editor: The Many Roles of RNA-Binding Proteins in Regulating A-to-I RNA Editing. | Adv Exp Med Biol | 2016 | Washburn MC | doi: 10.1007/978-3-319-29073-7_8. |
25826567 | Diverse selective regimes shape genetic diversity at ADAR genes and at their coding targets. | RNA Biol | 2015 | Forni D | doi: 10.1080/15476286.2015.1017215. |
28925356 | The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis. | Elife | 2017 Sep 19 | Deffit SN | doi: 10.7554/eLife.28625. |
28960389 | The Other Face of an Editor: ADAR1 Functions in Editing-Independent Ways. | Bioessays | 2017 Nov | Licht K | doi: 10.1002/bies.201700129 |
29127211 | Mechanistic implications of enhanced editing by a HyperTRIBE RNA-binding protein. | RNA | 2018 Feb | Xu W | doi: 10.1261/rna.064691.117 |
29694248 | ADAR1 attenuates allogeneic graft rejection by suppressing miR-21 biogenesis in macrophages and promoting M2 polarization. | FASEB J | 2018 Sep | Li J | doi: 10.1096/fj.201701449R |
29775506 | Dyschromatosis symmetrica hereditaria with chilblains due to a novel two-amino-acid deletion in the double-stranded RNA-binding domain of ADAR1. | J Eur Acad Dermatol Venereol | 2018 Oct | Kono M | doi: 10.1111/jdv.15076 |
30592616 | NMR Dynamics Study Reveals the Z-and-alpha; Domain of Human ADAR1 Associates with and Dissociates from Z-RNA More Slowly than Z-DNA. | ACS Chem Biol | 2019 Feb 15 | Lee AR | doi: 10.1021/acschembio.8b00914 |
30651363 | Adenosine Deaminase Acting on RNA 1 Associates with Orf Virus OV20.0 and Enhances Viral Replication. | J Virol | 2019 Mar 21 | Liao GR | doi: 10.1128/JVI.01912-18 |
31018137 | Disruption in A-to-I Editing Levels Affects C.elegans Development More Than a Complete Lack of Editing. | Cell Rep | 2019 Apr 23 | Ganem NS | doi: 10.1016/j.celrep.2019.03.095. |
17054412 | An artificial neural network approach to the drug efficacy of interferon treatments. | Pharmacogenomics | 2006 Oct | Lin E | - |
17979507 | Gene-gene and gene-environment interactions in interferon therapy for chronic hepatitis C. | Pharmacogenomics | 2007 Oct | Lin E | - |
17079286 | Double-stranded RNA deaminase ADAR1 increases host susceptibility to virus infection. | J Virol | 2007 Jan | Nie Y | - |
22104209 | ADAR1 is a novel multi targeted anti-HIV-1 cellular protein. | Virology | 2012 Jan 20 | Biswas N | doi: 10.1016/j.virol.2011.10.024 |
25921533 | Cis regulatory effects on A-to-I RNA editing in related Drosophila species. | Cell Rep | 2015 May 5 | Sapiro AL | doi: 10.1016/j.celrep.2015.04.005 |
29691780 | Combinatory RNA-Sequencing Analyses Reveal a Dual Mode of Gene Regulation by ADAR1 in Gastric Cancer. | Dig Dis Sci | 2018 Jul | Cho CJ | doi: 10.1007/s10620-018-5081-9 |
30013039 | Identification of RNA-binding protein targets with HyperTRIBE. | Nat Protoc | 2018 Aug | Rahman R | doi: 10.1038/s41596-018-0020-y. |
28575488 | A deep boosting based approach for capturing the sequence binding preferences of RNA-binding proteins from high-throughput CLIP-seq data. | Nucleic Acids Res | 2017 Aug 21 | Li S | doi: 10.1093/nar/gkx492. |
17224799 | Adenosine deaminase acting on RNA 1 accelerates cell cycle through increased translation and activity of cyclin-dependent kinase 2. | Shock | 2007 Feb | Zhang F | - |
26184879 | Dynamic profiling of double-stranded RNA binding proteins. | Nucleic Acids Res | 2015 Sep 3 | Wang X | doi: 10.1093/nar/gkv726 |
29364877 | Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation. | Nature | 2018 Feb 1 | Shen Q | doi: 10.1038/nature25434 |
11230159 | Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. | Genome Res | 2001 Mar | Marenholz I | - |
16886895 | Genetic predisposition of responsiveness to therapy for chronic hepatitis C. | Pharmacogenomics | 2006 Jul | Hwang Y | - |
28924040 | A B-Z junction induced by an A...A mismatch in GAC repeats in the gene for cartilage oligomeric matrix protein promotes binding with the hZ-and-alpha;ADAR1 protein. | J Biol Chem | 2017 Nov 17 | Kolimi N | doi: 10.1074/jbc.M117.796235 |
28985428 | An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer. | Nucleic Acids Res | 2017 Oct 13 | Qi L | doi: 10.1093/nar/gkx667. |
10535945 | The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA. | Proc Natl Acad Sci U S A | 1999 Oct 26 | Schade M | - |
9889202 | Structure-function analysis of the Z-DNA-binding domain Zalpha of dsRNA adenosine deaminase type I reveals similarity to the (alpha + beta) family of helix-turn-helix proteins. | EMBO J | 1999 Jan 15 | Schade M | - |
9671809 | The Zalpha domain from human ADAR1 binds to the Z-DNA conformer of many different sequences. | Nucleic Acids Res | 1998 Aug 1 | Herbert A | - |
8595560 | Deamination of mammalian glutamate receptor RNA by Xenopus dsRNA adenosine deaminase: similarities to in vivo RNA editing. | RNA | 1995 Dec | Hurst SR | - |
7615504 | Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts. | J Biol Chem | 1995 Jul 21 | Lai F | - |
11842111 | Complex regulation of the human gene for the Z-DNA binding protein DLM-1. | Nucleic Acids Res | 2002 Feb 15 | Rothenburg S | - |
11524677 | Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins. | Nat Struct Biol | 2001 Sep | Schwartz T | - |
19276205 | Human genomic Z-DNA segments probed by the Z alpha domain of ADAR1. | Nucleic Acids Res | 2009 May | Li H | doi: 10.1093/nar/gkp124 |
17268113 | Identification of novel ligands for the Z-DNA binding protein by structure-based virtual screening. | Chem Pharm Bull (Tokyo) | 2007 Feb | Kim YG | - |
20439751 | Crystal structure of a junction between two Z-DNA helices. | Proc Natl Acad Sci U S A | 2010 May 18 | de Rosa M | doi: 10.1073/pnas.1003182107 |
25344900 | Understanding the recognition mechanisms of Z-and-alpha; domain of human editing enzyme ADAR1 (hZ-and-alpha;(ADAR1)) and various Z-DNAs from molecular dynamics simulation. | J Mol Model | 2014 Nov | Wang Q | doi: 10.1007/s00894-014-2500-5 |
24719423 | hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication. | J Virol | 2014 Jul | Li Y | doi: 10.1128/JVI.00225-14 |
24067935 | ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding. | RNA | 2013 Nov | Wang Q | doi: 10.1261/rna.041533.113 |
27112566 | Adenosine to Inosine editing frequency controlled by splicing efficiency. | Nucleic Acids Res | 2016 Jul 27 | Licht K | doi: 10.1093/nar/gkw325 |
25751603 | Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways. | Nat Commun | 2015 Mar 9 | Bahn JH | doi: 10.1038/ncomms7355. |
29395325 | Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown. | Cell | 2018 Feb 8 | Chung H | doi: 10.1016/j.cell.2017.12.038 |
29950133 | Base-pairing probability in the microRNA stem region affects the binding and editing specificity of human A-to-I editing enzymes ADAR1-p110 and ADAR2. | RNA Biol | 2018 | Ishiguro S | doi: 10.1080/15476286.2018.1486658 |
30304469 | The C-terminal D/E-rich domain of MBD3 is a putative Z-DNA mimic that competes for Z-and-alpha; DNA-binding activity. | Nucleic Acids Res | 2018 Dec 14 | Lee CH | doi: 10.1093/nar/gky933. |