EuRBPDB

Description

Ensembl ID: ENSG00000161204 (Gene tree)
Gene ID: 55324
Gene Symbol: ABCF3
Alias: EST201864
Full Name: ATP binding cassette subfamily F member 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 8,430 bases
Position: chr3:184,186,023-184,194,452
Accession: 72
RBP type: non-canonical RBP
Summary: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. The protein encoded by this gene displays antiviral effect against flaviviruses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000489719	ABCF3-217	569	-	-	- (aa)	-	-
ENST00000466416	ABCF3-205	554	-	-	- (aa)	-	-
ENST00000481116	ABCF3-215	568	-	-	- (aa)	-	-
ENST00000471226	ABCF3-208	650	-	-	- (aa)	-	-
ENST00000429586	ABCF3-203	2624	-	ENSP00000411471	709 (aa)	-	Q9NUQ8
ENST00000468892	ABCF3-207	1360	-	-	- (aa)	-	-
ENST00000472608	ABCF3-209	657	-	-	- (aa)	-	-
ENST00000421340	ABCF3-202	690	-	ENSP00000415704	103 (aa)	-	F8WCU6
ENST00000292808	ABCF3-201	2453	XM_024453624	ENSP00000292808	703 (aa)	XP_024309392	Q9NUQ8
ENST00000498136	ABCF3-218	1014	-	-	- (aa)	-	-
ENST00000478288	ABCF3-212	754	-	-	- (aa)	-	-
ENST00000485921	ABCF3-216	813	-	-	- (aa)	-	-
ENST00000473311	ABCF3-210	2844	-	-	- (aa)	-	-
ENST00000466742	ABCF3-206	2331	-	-	- (aa)	-	-
ENST00000480539	ABCF3-213	533	-	-	- (aa)	-	-
ENST00000475728	ABCF3-211	503	-	-	- (aa)	-	-
ENST00000480562	ABCF3-214	1182	-	-	- (aa)	-	-
ENST00000463685	ABCF3-204	661	-	-	- (aa)	-	-

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000161204	rs35315125	3	184187521	?	Cardiovascular disease	30595370			EFO_0000319
ENSG00000161204	rs843339	3	184191375	?	Mean corpuscular hemoglobin	30595370			EFO_0004527

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000161204	ABCF3	99	56.938	FBgn0036888	CG9330	98	56.938	Drosophila_melanogaster
ENSG00000161204	ABCF3	98	43.467	YFR009W		98	43.467	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	21516116.25416956.26871637.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0016887	ATPase activity	-	IEA	Function
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0051607	defense response to virus	-	IEA	Process