EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000162437 (Gene tree)
Gene ID: 55225
Gene Symbol: RAVER2
Alias: KIAA1579|FLJ10770
Full Name: ribonucleoprotein, PTB binding 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 88,269 bases
Position: chr1:64,744,964-64,833,232
Accession: 25577
RBP type: canonical RBP
Summary: (Ribonucleoprotein, PTB Binding 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is RAVER1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000360112	RRM_1	PF00076.22	4.2e-28	1	3
ENSP00000360112	RRM_1	PF00076.22	4.2e-28	2	3
ENSP00000360112	RRM_1	PF00076.22	4.2e-28	3	3
ENSP00000294428	RRM_1	PF00076.22	4.5e-28	1	3
ENSP00000294428	RRM_1	PF00076.22	4.5e-28	2	3
ENSP00000294428	RRM_1	PF00076.22	4.5e-28	3	3

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000371072	RAVER2-202	4362	-	ENSP00000360112	678 (aa)	-	Q9HCJ3
ENST00000294428	RAVER2-201	4398	XM_006710738	ENSP00000294428	691 (aa)	XP_006710801	Q9HCJ3
ENST00000418058	RAVER2-203	2531	-	ENSP00000397069	166 (aa)	-	E9PE10

Gene Model

Click here to download ENSG00000162437's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000162437	Receptors, Tumor Necrosis Factor	5.3650000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000162437	rs12752552	1	64763616	T	Glioblastoma	29743610	[1.15-1.42]	1.28	EFO_0005543
ENSG00000162437	rs12752552	1	64763616	T	Glioma	29743610	[1.14-1.37]	1.25	EFO_0005543
ENSG00000162437	rs12752552	1	64763616	T	Glioblastoma	28346443	1.15-1.31	1.22	EFO_0000326\|EFO_0000519

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000162437's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000162437	RAVER2	84	42.857	ENSG00000161847	RAVER1	72	52.174

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000162437	RAVER2	92	42.424	ENSAPOG00000002766	raver2	63	52.166	Acanthochromis_polyacanthus
ENSG00000162437	RAVER2	99	86.441	ENSAMEG00000015178	RAVER2	99	92.846	Ailuropoda_melanoleuca
ENSG00000162437	RAVER2	92	41.818	ENSATEG00000019679	raver2	83	58.583	Anabas_testudineus
ENSG00000162437	RAVER2	99	62.222	ENSAPLG00000013160	RAVER2	100	67.208	Anas_platyrhynchos
ENSG00000162437	RAVER2	98	61.143	ENSACAG00000008443	RAVER2	89	65.667	Anolis_carolinensis
ENSG00000162437	RAVER2	95	96.336	ENSANAG00000025857	RAVER2	96	96.336	Aotus_nancymaae
ENSG00000162437	RAVER2	83	48.071	ENSACLG00000001840	raver2	69	48.232	Astatotilapia_calliptera
ENSG00000162437	RAVER2	89	44.025	ENSAMXG00000010570	raver2	67	51.890	Astyanax_mexicanus
ENSG00000162437	RAVER2	96	90.663	ENSBTAG00000030686	RAVER2	96	90.909	Bos_taurus
ENSG00000162437	RAVER2	99	96.341	ENSCJAG00000016724	RAVER2	95	95.672	Callithrix_jacchus
ENSG00000162437	RAVER2	99	85.311	ENSCAFG00000018617	RAVER2	100	92.105	Canis_familiaris
ENSG00000162437	RAVER2	95	91.450	ENSCAFG00020018120	RAVER2	95	90.923	Canis_lupus_dingo
ENSG00000162437	RAVER2	95	90.868	ENSCHIG00000005514	RAVER2	96	90.744	Capra_hircus
ENSG00000162437	RAVER2	99	87.006	ENSTSYG00000006019	RAVER2	88	93.914	Carlito_syrichta
ENSG00000162437	RAVER2	99	60.366	ENSCAPG00000013527	RAVER2	98	69.210	Cavia_aperea
ENSG00000162437	RAVER2	94	65.839	ENSCPOG00000005986	RAVER2	99	64.297	Cavia_porcellus
ENSG00000162437	RAVER2	95	95.599	ENSCCAG00000029834	RAVER2	96	95.613	Cebus_capucinus
ENSG00000162437	RAVER2	99	98.780	ENSCATG00000040658	RAVER2	100	97.898	Cercocebus_atys
ENSG00000162437	RAVER2	88	68.456	ENSCLAG00000006590	RAVER2	100	68.456	Chinchilla_lanigera
ENSG00000162437	RAVER2	99	98.171	ENSCSAG00000001350	RAVER2	100	97.896	Chlorocebus_sabaeus
ENSG00000162437	RAVER2	99	87.006	ENSCHOG00000007668	RAVER2	96	88.333	Choloepus_hoffmanni
ENSG00000162437	RAVER2	100	67.028	ENSCPBG00000001015	RAVER2	86	69.833	Chrysemys_picta_bellii
ENSG00000162437	RAVER2	99	97.561	ENSCANG00000042311	RAVER2	100	96.998	Colobus_angolensis_palliatus
ENSG00000162437	RAVER2	96	80.484	ENSCGRG00001011852	Raver2	98	80.451	Cricetulus_griseus_chok1gshd
ENSG00000162437	RAVER2	62	79.612	ENSCGRG00000011814	-	100	87.261	Cricetulus_griseus_crigri
ENSG00000162437	RAVER2	57	56.477	ENSCSEG00000017839	raver2	91	58.311	Cynoglossus_semilaevis
ENSG00000162437	RAVER2	86	42.484	ENSCVAG00000002687	raver2	85	58.421	Cyprinodon_variegatus
ENSG00000162437	RAVER2	92	45.455	ENSDARG00000075034	raver2	67	53.401	Danio_rerio
ENSG00000162437	RAVER2	95	91.641	ENSDNOG00000012130	RAVER2	96	91.515	Dasypus_novemcinctus
ENSG00000162437	RAVER2	96	84.441	ENSDORG00000002498	Raver2	91	84.545	Dipodomys_ordii
ENSG00000162437	RAVER2	89	69.903	ENSETEG00000000706	RAVER2	97	70.098	Echinops_telfairi
ENSG00000162437	RAVER2	99	81.921	ENSEASG00005008158	RAVER2	100	86.212	Equus_asinus_asinus
ENSG00000162437	RAVER2	99	81.921	ENSECAG00000022014	RAVER2	100	86.688	Equus_caballus
ENSG00000162437	RAVER2	77	46.795	ENSELUG00000022384	raver2	84	66.359	Esox_lucius
ENSG00000162437	RAVER2	94	91.859	ENSFCAG00000022781	RAVER2	97	91.377	Felis_catus
ENSG00000162437	RAVER2	99	61.798	ENSFALG00000012634	RAVER2	100	60.261	Ficedula_albicollis
ENSG00000162437	RAVER2	91	66.613	ENSFDAG00000010721	RAVER2	100	66.613	Fukomys_damarensis
ENSG00000162437	RAVER2	85	47.611	ENSFHEG00000001322	raver2	68	48.697	Fundulus_heteroclitus
ENSG00000162437	RAVER2	66	66.977	ENSGMOG00000013535	raver2	75	66.977	Gadus_morhua
ENSG00000162437	RAVER2	98	64.571	ENSGALG00000033759	RAVER2	84	67.127	Gallus_gallus
ENSG00000162437	RAVER2	86	41.830	ENSGAFG00000008577	raver2	68	48.208	Gambusia_affinis
ENSG00000162437	RAVER2	93	39.759	ENSGACG00000007122	raver2	94	49.743	Gasterosteus_aculeatus
ENSG00000162437	RAVER2	99	63.842	ENSGAGG00000018767	RAVER2	89	69.153	Gopherus_agassizii
ENSG00000162437	RAVER2	96	94.545	ENSGGOG00000016447	RAVER2	100	95.216	Gorilla_gorilla
ENSG00000162437	RAVER2	83	48.071	ENSHBUG00000022983	raver2	69	48.232	Haplochromis_burtoni
ENSG00000162437	RAVER2	93	67.438	ENSHGLG00000018409	RAVER2	99	66.566	Heterocephalus_glaber_female
ENSG00000162437	RAVER2	87	67.381	ENSHGLG00100006640	RAVER2	97	71.311	Heterocephalus_glaber_male
ENSG00000162437	RAVER2	78	49.647	ENSHCOG00000005933	raver2	65	49.826	Hippocampus_comes
ENSG00000162437	RAVER2	89	49.287	ENSIPUG00000007082	raver2	81	51.712	Ictalurus_punctatus
ENSG00000162437	RAVER2	99	61.017	ENSSTOG00000009844	RAVER2	99	83.529	Ictidomys_tridecemlineatus
ENSG00000162437	RAVER2	93	80.650	ENSJJAG00000000374	Raver2	100	79.066	Jaculus_jaculus
ENSG00000162437	RAVER2	86	43.791	ENSKMAG00000011656	raver2	70	68.056	Kryptolebias_marmoratus
ENSG00000162437	RAVER2	94	47.904	ENSLACG00000005188	RAVER2	75	49.561	Latimeria_chalumnae
ENSG00000162437	RAVER2	90	50.157	ENSLOCG00000006773	raver2	75	50.155	Lepisosteus_oculatus
ENSG00000162437	RAVER2	99	86.441	ENSLAFG00000012508	RAVER2	100	91.790	Loxodonta_africana
ENSG00000162437	RAVER2	99	98.780	ENSMFAG00000031436	RAVER2	100	93.198	Macaca_fascicularis
ENSG00000162437	RAVER2	99	98.171	ENSMMUG00000018565	RAVER2	100	97.548	Macaca_mulatta
ENSG00000162437	RAVER2	99	98.780	ENSMNEG00000033127	RAVER2	100	97.723	Macaca_nemestrina
ENSG00000162437	RAVER2	99	98.780	ENSMLEG00000036310	RAVER2	100	98.151	Mandrillus_leucophaeus
ENSG00000162437	RAVER2	71	44.068	ENSMAMG00000009059	raver2	81	59.128	Mastacembelus_armatus
ENSG00000162437	RAVER2	83	48.071	ENSMZEG00005014386	raver2	69	48.232	Maylandia_zebra
ENSG00000162437	RAVER2	98	65.714	ENSMGAG00000011806	RAVER2	100	68.455	Meleagris_gallopavo
ENSG00000162437	RAVER2	96	79.274	ENSMAUG00000004248	Raver2	98	79.248	Mesocricetus_auratus
ENSG00000162437	RAVER2	96	93.967	ENSMICG00000029259	RAVER2	95	94.529	Microcebus_murinus
ENSG00000162437	RAVER2	96	78.916	ENSMOCG00000018087	Raver2	97	78.916	Microtus_ochrogaster
ENSG00000162437	RAVER2	99	76.970	ENSMODG00000001242	RAVER2	94	71.822	Monodelphis_domestica
ENSG00000162437	RAVER2	93	40.909	ENSMALG00000018093	raver2	70	47.994	Monopterus_albus
ENSG00000162437	RAVER2	93	82.016	MGP_CAROLIEiJ_G0026202	Raver2	97	83.146	Mus_caroli
ENSG00000162437	RAVER2	93	82.016	ENSMUSG00000035275	Raver2	97	83.596	Mus_musculus
ENSG00000162437	RAVER2	93	81.705	MGP_PahariEiJ_G0028539	Raver2	96	83.447	Mus_pahari
ENSG00000162437	RAVER2	93	82.171	MGP_SPRETEiJ_G0027171	Raver2	97	83.596	Mus_spretus
ENSG00000162437	RAVER2	99	86.441	ENSMPUG00000000717	RAVER2	100	91.601	Mustela_putorius_furo
ENSG00000162437	RAVER2	99	92.683	ENSMLUG00000007699	RAVER2	100	91.971	Myotis_lucifugus
ENSG00000162437	RAVER2	98	79.259	ENSNGAG00000000905	Raver2	99	78.730	Nannospalax_galili
ENSG00000162437	RAVER2	99	99.390	ENSNLEG00000015145	RAVER2	100	98.510	Nomascus_leucogenys
ENSG00000162437	RAVER2	82	69.855	ENSMEUG00000012740	RAVER2	84	68.219	Notamacropus_eugenii
ENSG00000162437	RAVER2	98	48.571	ENSOPRG00000016988	-	68	75.676	Ochotona_princeps
ENSG00000162437	RAVER2	92	68.277	ENSODEG00000005253	RAVER2	100	68.277	Octodon_degus
ENSG00000162437	RAVER2	71	47.887	ENSONIG00000008808	raver2	73	49.109	Oreochromis_niloticus
ENSG00000162437	RAVER2	99	66.854	ENSOANG00000008327	-	100	68.567	Ornithorhynchus_anatinus
ENSG00000162437	RAVER2	95	81.763	ENSOCUG00000006221	RAVER2	95	81.791	Oryctolagus_cuniculus
ENSG00000162437	RAVER2	92	43.030	ENSORLG00000010073	raver2	66	51.568	Oryzias_latipes
ENSG00000162437	RAVER2	92	43.030	ENSORLG00020010822	raver2	64	51.473	Oryzias_latipes_hni
ENSG00000162437	RAVER2	50	62.722	ENSORLG00015000191	raver2	81	64.984	Oryzias_latipes_hsok
ENSG00000162437	RAVER2	92	43.030	ENSOMEG00000007789	raver2	71	49.605	Oryzias_melastigma
ENSG00000162437	RAVER2	98	81.818	ENSOGAG00000011157	RAVER2	100	84.918	Otolemur_garnettii
ENSG00000162437	RAVER2	95	90.868	ENSOARG00000010030	RAVER2	96	90.744	Ovis_aries
ENSG00000162437	RAVER2	95	98.936	ENSPPAG00000039189	RAVER2	99	98.936	Pan_paniscus
ENSG00000162437	RAVER2	94	91.705	ENSPPRG00000023350	RAVER2	96	91.225	Panthera_pardus
ENSG00000162437	RAVER2	99	84.181	ENSPTIG00000009389	RAVER2	88	92.270	Panthera_tigris_altaica
ENSG00000162437	RAVER2	100	99.115	ENSPTRG00000000824	RAVER2	100	99.115	Pan_troglodytes
ENSG00000162437	RAVER2	99	98.171	ENSPANG00000003396	RAVER2	100	96.925	Papio_anubis
ENSG00000162437	RAVER2	80	49.644	ENSPKIG00000019357	raver2	66	50.355	Paramormyrops_kingsleyae
ENSG00000162437	RAVER2	100	62.011	ENSPSIG00000010074	RAVER2	91	55.573	Pelodiscus_sinensis
ENSG00000162437	RAVER2	75	38.346	ENSPMGG00000017781	raver2	85	49.242	Periophthalmus_magnuspinnatus
ENSG00000162437	RAVER2	96	79.909	ENSPEMG00000001332	Raver2	98	79.880	Peromyscus_maniculatus_bairdii
ENSG00000162437	RAVER2	99	71.348	ENSPCIG00000020336	RAVER2	93	73.893	Phascolarctos_cinereus
ENSG00000162437	RAVER2	86	42.484	ENSPFOG00000009386	raver2	64	49.571	Poecilia_formosa
ENSG00000162437	RAVER2	86	41.830	ENSPLAG00000005632	raver2	65	50.000	Poecilia_latipinna
ENSG00000162437	RAVER2	86	41.830	ENSPMEG00000000509	raver2	65	50.000	Poecilia_mexicana
ENSG00000162437	RAVER2	86	41.176	ENSPREG00000020514	raver2	65	49.141	Poecilia_reticulata
ENSG00000162437	RAVER2	61	100.000	ENSPPYG00000001271	-	99	100.000	Pongo_abelii
ENSG00000162437	RAVER2	69	90.840	ENSPCAG00000000017	RAVER2	68	90.840	Procavia_capensis
ENSG00000162437	RAVER2	99	97.561	ENSPCOG00000028379	RAVER2	96	94.753	Propithecus_coquereli
ENSG00000162437	RAVER2	99	84.746	ENSPVAG00000007172	RAVER2	100	90.625	Pteropus_vampyrus
ENSG00000162437	RAVER2	89	44.654	ENSPNAG00000000962	raver2	70	67.281	Pygocentrus_nattereri
ENSG00000162437	RAVER2	93	81.395	ENSRNOG00000023812	Raver2	98	80.301	Rattus_norvegicus
ENSG00000162437	RAVER2	99	91.525	ENSRBIG00000044090	RAVER2	100	91.928	Rhinopithecus_bieti
ENSG00000162437	RAVER2	99	91.525	ENSRROG00000041867	RAVER2	90	98.390	Rhinopithecus_roxellana
ENSG00000162437	RAVER2	99	89.266	ENSSBOG00000023706	RAVER2	100	96.316	Saimiri_boliviensis_boliviensis
ENSG00000162437	RAVER2	99	71.508	ENSSHAG00000014568	RAVER2	100	74.675	Sarcophilus_harrisii
ENSG00000162437	RAVER2	86	43.137	ENSSFOG00015013015	raver2	70	51.149	Scleropages_formosus
ENSG00000162437	RAVER2	92	42.424	ENSSMAG00000020654	raver2	68	48.445	Scophthalmus_maximus
ENSG00000162437	RAVER2	92	42.424	ENSSDUG00000013065	raver2	69	48.693	Seriola_dumerili
ENSG00000162437	RAVER2	86	43.137	ENSSLDG00000002746	raver2	71	48.860	Seriola_lalandi_dorsalis
ENSG00000162437	RAVER2	99	66.667	ENSSPUG00000016441	RAVER2	97	69.466	Sphenodon_punctatus
ENSG00000162437	RAVER2	71	46.218	ENSSPAG00000004134	raver2	86	59.783	Stegastes_partitus
ENSG00000162437	RAVER2	95	88.754	ENSSSCG00000025672	-	95	88.788	Sus_scrofa
ENSG00000162437	RAVER2	98	62.500	ENSTGUG00000009973	RAVER2	100	64.248	Taeniopygia_guttata
ENSG00000162437	RAVER2	72	59.673	ENSTRUG00000018541	raver2	82	59.673	Takifugu_rubripes
ENSG00000162437	RAVER2	79	50.277	ENSTNIG00000018106	raver2	92	49.908	Tetraodon_nigroviridis
ENSG00000162437	RAVER2	88	82.895	ENSTBEG00000009004	RAVER2	100	82.895	Tupaia_belangeri
ENSG00000162437	RAVER2	99	86.441	ENSTTRG00000009692	RAVER2	83	89.583	Tursiops_truncatus
ENSG00000162437	RAVER2	99	77.401	ENSUAMG00000007847	RAVER2	90	84.323	Ursus_americanus
ENSG00000162437	RAVER2	98	83.429	ENSUMAG00000008489	RAVER2	93	89.491	Ursus_maritimus
ENSG00000162437	RAVER2	99	85.311	ENSVVUG00000013993	RAVER2	100	92.076	Vulpes_vulpes
ENSG00000162437	RAVER2	86	57.143	ENSXETG00000020406	raver2	79	53.539	Xenopus_tropicalis
ENSG00000162437	RAVER2	86	41.830	ENSXMAG00000002206	raver2	68	49.106	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005737	cytoplasm	-	IEA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	64807379	Missense_Mutation	NA	L529F	0.11
BLCA	chr1	64778071	Silent	NA	V255V	0.34
BLCA	chr1	64781489	Missense_Mutation	rs186869355	G299D	0.41	RRM_1
BRCA	chr1	64805087	Missense_Mutation	novel	H465D	0.09
BRCA	chr1	64789478	Silent	rs373293420	L357L	0.14
BRCA	chr1	64777823	Silent	NA	L173L	0.34
BRCA	chr1	64745287	Missense_Mutation	NA	E39K	0.21
CESC	chr1	64831140	3'UTR	novel		0.25
CESC	chr1	64777794	Missense_Mutation	rs199595651	R163H	0.3
CESC	chr1	64832116	3'UTR	novel		0.52
CESC	chr1	64832362	3'UTR	novel		0.37
CESC	chr1	64807349	Missense_Mutation	novel	E519K	0.1
COAD	chr1	64812789	Missense_Mutation	rs201820413	R578W	0.36
COAD	chr1	64830875	Missense_Mutation	novel	Y656N	0.4
COAD	chr1	64778008	Silent	novel	C234C	0.06
COAD	chr1	64830964	Frame_Shift_Del	novel	*K687Rfs15**	0.37
COAD	chr1	64777840	Silent	rs373913304	V178V	0.33
COAD	chr1	64803011	Missense_Mutation	NA	M381V	0.18
COAD	chr1	64807335	Missense_Mutation	rs114877918	T514M	0.35
COAD	chr1	64812742	Missense_Mutation	NA	A562V	0.45
COAD	chr1	64812789	Missense_Mutation	rs201820413	R578W	0.25
COAD	chr1	64807471	Silent	novel	S559S	0.35
COAD	chr1	64814830	Missense_Mutation	novel	D640G	0.1
COAD	chr1	64830964	Missense_Mutation	rs759218839	L685F	0.3
ESCA	chr1	64830964	Frame_Shift_Del	novel	*K687Rfs15**	0.21
ESCA	chr1	64803015	Missense_Mutation	novel	N382S	0.28
ESCA	chr1	64745301	Missense_Mutation	novel	D43E	0.2
GBM	chr1	64802976	Missense_Mutation	novel	A369V	0.5
HNSC	chr1	64805093	Missense_Mutation	novel	E467Q	0.19
HNSC	chr1	64812807	Missense_Mutation	novel	Y584H	0.18
HNSC	chr1	64812745	Missense_Mutation	novel	S563C	0.09
HNSC	chr1	64789475	Missense_Mutation	rs770009968	L356F	0.28
KIRC	chr1	64830996	3'UTR	novel		0.34
KIRP	chr1	64807271	Missense_Mutation	novel	N493H	0.36
LAML	chr1	64778001	Missense_Mutation	novel	C232Y	0.17
LGG	chr1	64807415	Missense_Mutation	novel	L541V	0.11
LGG	chr1	64768716	Nonsense_Mutation	rs757204301	R104*	0.22
LGG	chr1	64803046	Missense_Mutation	NA	L392F	0.15
LGG	chr1	64807268	Missense_Mutation	rs756061919	P492T	0.17
LIHC	chr1	64814750	Silent	NA	S613S	0.31
LIHC	chr1	64830949	Nonsense_Mutation	novel	Y680*	0.33
LIHC	chr1	64789442	Missense_Mutation	NA	K345E	0.35
LIHC	chr1	64777817	Missense_Mutation	novel	C171S	0.35
LIHC	chr1	64812822	Missense_Mutation	novel	S589G	0.47
LUAD	chr1	64777809	Missense_Mutation	rs572662102	I168T	0.08
LUAD	chr1	64777646	Missense_Mutation	novel	E114K	0.33
LUAD	chr1	64778023	Silent	novel	P239P	0.11
LUAD	chr1	64812833	Silent	novel	P592P	0.3
LUAD	chr1	64812814	Missense_Mutation	novel	N586I	0.06
LUAD	chr1	64768681	Missense_Mutation	novel	Y92S	0.15
LUAD	chr1	64805009	Missense_Mutation	NA	E439Q	0.41
LUSC	chr1	64807336	Silent	novel	T514T	0.12
LUSC	chr1	64805007	Missense_Mutation	NA	G438A	0.41
LUSC	chr1	64777918	Missense_Mutation	NA	L204F	0.25
LUSC	chr1	64777754	Missense_Mutation	novel	P150A	0.36
LUSC	chr1	64803027	Missense_Mutation	rs764101143	S386C	0.03
LUSC	chr1	64804770	Missense_Mutation	rs758901734	Q410E	0.18
LUSC	chr1	64777648	Silent	novel	E114E	0.55
LUSC	chr1	64777683	Missense_Mutation	novel	Y126C	0.48
LUSC	chr1	64814803	Missense_Mutation	novel	C631F	0.39
LUSC	chr1	64789476	Frame_Shift_Del	novel	*L357Yfs24**	0.85
LUSC	chr1	64777761	Missense_Mutation	novel	S152C	0.12
OV	chr1	64831235	3'UTR	rs535911153		0.54
PAAD	chr1	64802997	Missense_Mutation	novel	S376I	0.07
PRAD	chr1	64812790	Missense_Mutation	novel	R578Q	0.28
READ	chr1	64807228	Missense_Mutation	NA	Q478H	0.16
SARC	chr1	64777913	Frame_Shift_Ins	rs749647362	*L204Ifs3**	0.1
SKCM	chr1	64777694	Missense_Mutation	rs771478492	G130R	0.46
SKCM	chr1	64778048	Silent	rs371245537	L248L	0.4
SKCM	chr1	64781507	Missense_Mutation	NA	S305F	0.51
SKCM	chr1	64789400	Nonsense_Mutation	NA	Q331*	0.24
SKCM	chr1	64789418	Missense_Mutation	rs774421284	E337K	0.29
SKCM	chr1	64777847	Missense_Mutation	rs774986737	H181Y	0.55
SKCM	chr1	64831158	3'UTR	novel		0.43
SKCM	chr1	64802984	Missense_Mutation	NA	G372R	0.43
SKCM	chr1	64830965	Nonsense_Mutation	NA	K686*	0.52
SKCM	chr1	64807234	Silent	NA	T480T	0.4
SKCM	chr1	64807327	Silent	NA	Q511Q	0.37
STAD	chr1	64789502	Missense_Mutation	NA	A365T	0.11
STAD	chr1	64814803	Missense_Mutation	NA	C631Y	0.1
STAD	chr1	64830963	Frame_Shift_Ins	novel	*K688Efs7**	0.36
STAD	chr1	64777794	Missense_Mutation	rs199595651	R163H	0.37
STAD	chr1	64781379	Splice_Site	NA	X263_splice	0.39
STAD	chr1	64777686	Missense_Mutation	NA	S127F	0.38
STAD	chr1	64777661	Missense_Mutation	rs373988652	A119T	0.06
STAD	chr1	64807205	Splice_Site	NA	X471_splice	0.3
STAD	chr1	64777719	Missense_Mutation	NA	Q138R	0.21
UCEC	chr1	64805103	Missense_Mutation	NA	K470T	0.34
UCEC	chr1	64831299	3'UTR	novel		0.38
UCEC	chr1	64807353	Missense_Mutation	novel	G520E	0.28
UCEC	chr1	64781388	Missense_Mutation	novel	Q265H	0.52	RRM_1
UCEC	chr1	64830974	Nonsense_Mutation	rs753051685	R689*	0.32
UCEC	chr1	64745402	Missense_Mutation	novel	P77H	0.3
UCEC	chr1	64777700	Missense_Mutation	rs781074957	D132Y	0.34
UCEC	chr1	64832025	3'UTR	novel		0.14
UCEC	chr1	64777686	Frame_Shift_Ins	novel	R129*	0.44
UCEC	chr1	64807205	Splice_Site	novel	X471_splice	0.39
UCEC	chr1	64832244	3'UTR	novel		0.41
UCEC	chr1	64777842	Missense_Mutation	novel	T179I	0.24
UCEC	chr1	64768657	Missense_Mutation	NA	E84A	0.15
UCEC	chr1	64807460	Nonsense_Mutation	NA	E556*	0.33
UCEC	chr1	64781549	Missense_Mutation	NA	A319E	0.12
UCEC	chr1	64745423	Splice_Site	novel	X83_splice	0.34
UCEC	chr1	64768717	Missense_Mutation	NA	R104Q	0.32
UCEC	chr1	64807369	Silent	novel	S525S	0.26
UCEC	chr1	64830943	Silent	novel	A678A	0.29
UCEC	chr1	64781473	Missense_Mutation	novel	G294S	0.39	RRM_1
UCEC	chr1	64777828	Silent	novel	V174V	0.24
UCEC	chr1	64781487	Missense_Mutation	novel	K298N	0.28	RRM_1
UCEC	chr1	64814749	Missense_Mutation	novel	S613N	0.43
UCEC	chr1	64777775	Missense_Mutation	novel	E157K	0.56
UCEC	chr1	64831335	3'UTR	novel		0.51
UCEC	chr1	64789452	Missense_Mutation	novel	N348S	0.33
UCEC	chr1	64832299	3'UTR	novel		0.09
UCEC	chr1	64831417	3'UTR	novel		0.44
UCEC	chr1	64781560	Missense_Mutation	novel	A323T	0.29
UCEC	chr1	64814727	Missense_Mutation	novel	H606Y	0.26
UCEC	chr1	64814765	Silent	novel	I618I	0.19
UCEC	chr1	64777863	Missense_Mutation	rs377369065	G186V	0.42
UCEC	chr1	64833193	3'UTR	novel		0.33
UCEC	chr1	64777862	Nonsense_Mutation	novel	G186*	0.37
UCEC	chr1	64781534	Missense_Mutation	rs752817197	R314Q	0.35
UCEC	chr1	64781533	Nonsense_Mutation	rs765722380	R314*	0.5
UCEC	chr1	64831059	3'UTR	novel		0.44
UCEC	chr1	64804999	Silent	novel	G435G	0.08
UCEC	chr1	64768717	Missense_Mutation	NA	R104Q	0.08
UCEC	chr1	64807369	Silent	novel	S525S	0.42
UCEC	chr1	64805103	Missense_Mutation	NA	K470T	0.06
UCEC	chr1	64830852	Missense_Mutation	NA	R648I	0.25
UCEC	chr1	64768723	Splice_Site	novel	X106_splice	0.33
UCEC	chr1	64831480	3'UTR	novel		0.29
UCEC	chr1	64804829	Silent	novel	H429H	0.24
UCEC	chr1	64832299	3'UTR	novel		0.39
UCEC	chr1	64777639	Missense_Mutation	novel	L111F	0.47
UCEC	chr1	64789468	Silent	novel	L353L	0.35
UCEC	chr1	64832415	3'UTR	novel		0.41
UCEC	chr1	64777707	Missense_Mutation	novel	I134T	0.39
UCEC	chr1	64830893	Nonsense_Mutation	novel	E662*	0.4

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
COAD	DEL	0.2373	0.00038973
PRAD	DEL	0.1037	0.000642
TGCT	DEL	0.16	0.023574

Survival Analysis

Cancer	P-value	Q-value
MESO	0.0042	Kaplan-Meier Survival Analysis
HNSC	0.045	Kaplan-Meier Survival Analysis
LUSC	0.0012	Kaplan-Meier Survival Analysis
KIRP	0.033	Kaplan-Meier Survival Analysis
CESC	0.043	Kaplan-Meier Survival Analysis
READ	0.0052	Kaplan-Meier Survival Analysis
LAML	0.005	Kaplan-Meier Survival Analysis
LIHC	0.024	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742